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$185+ Cheap flights from Harrisburg to Charleston (MDT - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find cheap flights from Harrisburg to Charleston with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Harrisburg to Charleston are usually found in August or May, booked 28 days in advance, depart on a Tuesday or Thursday and return on a Thursday

Cheap flight deals from Harrisburg to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

One-way from

$185
(Delta)

Popular in

December

Cheapest in

August

Average price

$333
Provider with most accurate pricing for Harrisburg-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Charleston flights.
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From Harrisburg to Charleston
Search Deals
One-way flight from Harrisburg to Charleston
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Harrisburg to Charleston

Cheapest flights from Harrisburg to Charleston
Explore the most affordable flight options available from Harrisburg to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/65:00 amMDT - CHS
1 stop3h 29mAmerican Airlines
Mon 11/107:12 pmCHS - MDT
1 stop4h 41mAmerican Airlines
Deal found 10/27$249
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/166:27 amMDT - CHS
1 stop3h 56mAmerican Airlines
Tue 11/188:00 amCHS - MDT
2 stops6h 29mAmerican Airlines
Deal found 10/28$274
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:30 amMDT - CHS
1 stop7h 25mUnited Airlines
Mon 11/2410:00 amCHS - MDT
1 stop3h 58mUnited Airlines
Deal found 10/27$277
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/245:40 amMDT - CHS
1 stop5h 55mAmerican Airlines
Fri 11/284:15 pmCHS - MDT
1 stop4h 43mAmerican Airlines
Deal found 10/26$280
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/118:15 amMDT - CHS
1 stop5h 40mUnited Airlines
Sat 11/1511:25 amCHS - MDT
1 stop5h 28mUnited Airlines
Deal found 10/27$319
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/118:15 amMDT - CHS
1 stop5h 40mUnited Airlines
Fri 11/1411:25 amCHS - MDT
1 stop7h 50mUnited Airlines
Deal found 10/28$339
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:15 amMDT - CHS
1 stop4h 11mAmerican Airlines
Sun 11/27:53 pmCHS - MDT
1 stop4h 26mAmerican Airlines
Deal found 10/27$349
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:31 pmMDT - CHS
1 stop21h 57mMultiple Airlines
Sun 12/149:49 pmCHS - MDT
2 stops19h 53mMultiple Airlines
Deal found 10/27$351
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:00 amMDT - CHS
1 stop3h 29mAmerican Airlines
Tue 12/28:00 amCHS - MDT
2 stops6h 29mAmerican Airlines
Deal found 10/28$364
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/72:55 pmMDT - CHS
1 stop6h 09mAmerican Airlines
Tue 11/117:12 pmCHS - MDT
1 stop4h 41mAmerican Airlines
Deal found 10/27$369
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:00 amMDT - CHS
1 stop3h 35mAmerican Airlines
Sat 12/278:08 pmCHS - MDT
1 stop4h 11mAmerican Airlines
Deal found 10/27$387

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Harrisburg to Charleston that are best for you.

Fly from

Harrisburg

Fly to

Charleston

Route

Depart

Return

Price

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Wed 12/10

6:00 am-10:46 am

1 stop4h 46m

Charleston

Sun 12/14

6:31 pm-11:13 pm

1 stop4h 42m

$249

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Thu 11/20

6:40 am-10:25 am

1 stop3h 45m

Charleston

Sat 11/22

7:53 pm-12:22 am

1 stop4h 29m

$249

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Thu 1/15

10:34 am-2:48 pm

1 stop4h 14m

Charleston

Sun 1/18

6:05 am-2:15 pm

1 stop8h 10m

$249

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Sat 11/8

6:30 am-1:55 pm

1 stop7h 25m

Charleston

Tue 11/11

10:00 am-1:58 pm

1 stop3h 58m

$249

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Thu 11/6

5:00 am-8:29 am

1 stop3h 29m

Charleston

Mon 11/10

5:39 pm-11:53 pm

1 stop6h 14m

$249

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Fri 12/5

6:00 am-10:46 am

1 stop4h 46m

Charleston

Mon 12/8

5:25 am-10:48 am

1 stop5h 23m

$249

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Thu 1/15

4:47 pm-9:11 pm

1 stop4h 24m

Charleston

Sun 1/18

8:00 am-2:38 pm

2 stops6h 38m

$254

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Wed 1/21

6:04 pm-2:31 pm

1 stop20h 27m

Charleston

Sun 1/25

8:59 pm-5:13 pm

1 stop20h 14m

$259

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Wed 1/7

3:03 pm-11:07 pm

2 stops8h 04m

Charleston

Sat 1/10

2:06 pm-8:14 pm

2 stops6h 08m

$259

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Mon 12/8

6:00 am-10:46 am

1 stop4h 46m

$185

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 14 results
1
2

Compare providers for flights from Harrisburg to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Charleston in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Harrisburg-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Harrisburg-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Charleston

How far ahead should I book a flight from Harrisburg to Charleston?

Use this chart to determine the optimal time to book a round-trip flight from Harrisburg to Charleston. Price data was last updated on October 24, 2025.

The price you pay for your flight from Harrisburg to Charleston may vary depending on when you book. For the best chance of a lower fare, look to book 28 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Harrisburg to Charleston?

Currently, June is the cheapest month in which you can book a flight from Harrisburg to Charleston (average of $84). Flying from Harrisburg to Charleston in November is currently the most expensive (average of $190). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to CHS?

Find hourly flight availability from Harrisburg to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

A simple way to save on the total cost of your ticket is to fly from Harrisburg to Charleston in the evening. If you’re flexible enough to do this you can expect to save up to 15% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated October 29, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Harrisburg to Charleston by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Charleston?

    Airlines like Delta, American Airlines, and United Airlines fly from Harrisburg to Charleston in about 3h 45m. The time it takes to get you to your destination can typically vary by up to 1h 01m. The distance between Harrisburg and Charleston is about 536 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Harrisburg to Charleston round-trip?

    According to our current data, American Airlines ($248), United Airlines ($248), and Delta ($253) offers the cheapest pricing from Harrisburg to Charleston. American Airlines is priced at 29% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Harrisburg to Charleston that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Charleston.

  • Can I find deals for business class flights from Harrisburg to Charleston?

    Yes. Cheapflights offers flight deals from Harrisburg to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Charleston?

    Currently, June is the cheapest month in which you can book a flight from Harrisburg to Charleston (average of $84). Flying from Harrisburg to Charleston in November is currently the most expensive (average of $190). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Isle of Palms
Santee
Mount Pleasant
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Harrisburg to Charleston

Discover the top 3 airlines that operate flights from Harrisburg to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$483FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$362FlexibilityNo cancel feeOn-time71%
DeltaCheapest$253Average$333FlexibilityNo cancel feeOn-timeN/A

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