$388+ Cheap flights from St. Louis (STL) to the Cayman Islands
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
jan 4 — jan 111
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Cayman Islands
Cheapest flights from St. Louis to Cayman IslandsExplore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on dezembro 5, 2025.
Explore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on dezembro 5, 2025.
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 12/196:00 amSTL - GCM
1 stop9h 00mUnited Airlines
ter 12/235:45 pmGCM - STL
1 stop17h 04mUnited Airlines
Deal found 12/3![United Airlines logo]()
$516
Find flight deals from St. Louis to Cayman Islands
Keep the following information in mind while searching for St. Louis to Cayman Islands flight deals. Data was last updated dezembro 5, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $388 (American Airlines) |
Popular in | March |
Cheapest in | September |
Average price | $661 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated dezembro 5, 2025.
Use the filters below to find and compare flights from St. Louis to the Cayman Islands that are best for you.
Fly from
St. Louis
Fly to
Cayman Islands
Route
Depart
Return
Price
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
sáb 4/18
7:03 pm-10:45 am
2 stops15h 42m
George Town Owen Roberts Intl
sáb 5/2
3:20 pm-8:55 am
1 stop17h 35m
$388
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
ter 1/20
10:00 am-8:20 pm
1 stop9h 20m
George Town Owen Roberts Intl
sáb 1/24
12:35 pm-10:44 pm
1 stop11h 09m
$391
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
sáb 2/7
5:04 pm-11:50 am
2 stops17h 46m
George Town Owen Roberts Intl
sáb 2/14
12:37 pm-11:02 pm
1 stop11h 25m
$396
Best time to book a flight from St. Louis to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to the Cayman Islands
What is the cheapest month to book a flight from St. Louis to Cayman Islands?
Currently, August is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $267). Flying from St. Louis to Cayman Islands in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Cayman Islands
Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated dezembro 5, 2025.
Read through reviews of airlines operating flights from St. Louis to the Cayman Islands, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to Cayman Islands
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from St. Louis to Cayman Islands
Discover the top 4 airlines that operate flights from St. Louis to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated dezembro 5, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$266 | Average$613 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$424 | Average$606 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$429 | Average$581 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$469 | Average$724 | FlexibilityNo cancel fee | On-time69% |