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Cayman Islands

$106+ Cheap flights from St. Louis (STL) to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Feb 19 — Feb 261
Thu 2/19
Thu 2/26
1 adult, Economy
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Cheap flight deals from St. Louis to Cayman Islands

Cheapest flights from St. Louis to Cayman Islands
Explore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

This Delta deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:00 am
STL
-
GCM
1 stop5h 29m
Delta
Wed 3/41:54 pm
GCM
-
STL
1 stop6h 45m
Delta
Deal found 1/18$317
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:00 am
STL
-
GCM
2 stops13h 15m
American Airlines
Wed 3/112:35 pm
GCM
-
STL
2 stops9h 13m
American Airlines
Deal found 1/18$322
This Delta deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:56 pm
STL
-
GCM
1 stop16h 33m
Delta
Wed 3/41:54 pm
GCM
-
STL
1 stop10h 42m
Delta
Deal found 1/18$352
This Delta deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:35 pm
STL
-
GCM
1 stop18h 26m
Delta
Tue 3/31:54 pm
GCM
-
STL
1 stop10h 42m
Delta
Deal found 1/18$377
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:11 pm
STL
-
GCM
2 stops17h 21m
American Airlines
Sat 5/22:10 pm
GCM
-
STL
2 stops18h 13m
American Airlines
Deal found 1/18$382
This Air Canada deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:05 pm
STL
-
GCM
1 stop19h 05m
Air Canada
Sat 5/212:25 pm
GCM
-
STL
1 stop7h 39m
Air Canada
Deal found 1/19$384
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:36 pm
STL
-
GCM
1 stop18h 59m
American Airlines
Wed 3/412:58 pm
GCM
-
STL
2 stops11h 50m
American Airlines
Deal found 1/18$388
This Delta deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:56 pm
STL
-
GCM
1 stop16h 33m
Delta
Mon 3/21:54 pm
GCM
-
STL
1 stop7h 47m
Delta
Deal found 1/18$412
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/146:00 am
STL
-
GCM
1 stop7h 15m
Delta
Sat 2/213:56 pm
GCM
-
STL
1 stop8h 27m
Delta
Deal found 1/19$437
This Air Canada deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/284:05 pm
STL
-
GCM
1 stop19h 20m
Air Canada
Thu 2/261:30 pm
GCM
-
STL
1 stop26h 59m
Air Canada
Deal found 1/18$438
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:00 am
STL
-
GCM
2 stops13h 15m
American Airlines
Mon 2/2312:50 pm
GCM
-
STL
2 stops11h 58m
American Airlines
Deal found 1/18$443
This Air Canada deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/314:05 pm
STL
-
GCM
1 stop19h 20m
Air Canada
Tue 2/241:30 pm
GCM
-
STL
1 stop26h 59m
Air Canada
Deal found 1/18$449

Find flight deals from St. Louis to Cayman Islands

Keep the following information in mind while searching for St. Louis to Cayman Islands flight deals. Data was last updated January 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$377
(American Airlines)

One-way from

$106
(Delta)

Popular in

March

Cheapest in

September

Average price

$571
Provider with most accurate pricing for Lambert-St Louis-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-George Town Owen Roberts Intl flights.
Search Deals
From Lambert-St Louis to Cayman Islands
Search Deals
One-way flight from Lambert-St Louis to Cayman Islands
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from St. Louis to the Cayman Islands that are best for you.

Fly from

St. Louis

Fly to

Cayman Islands

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/18

6:53 pm-11:32 am

1 stop16h 39m

George Town Owen Roberts Intl

Sat 5/2

3:13 pm-11:04 pm

1 stop7h 51m

$377

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 2/20

6:10 am-2:40 pm

1 stop7h 30m

George Town Owen Roberts Intl

Fri 2/27

1:54 pm-8:41 pm

1 stop7h 47m

$377

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Thu 3/5

6:06 am-8:15 pm

2 stops13h 09m

George Town Owen Roberts Intl

Thu 3/12

7:45 am-11:58 pm

1 stop16h 13m

$382

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 2/21

6:00 am-12:29 pm

1 stop5h 29m

George Town Owen Roberts Intl

Mon 3/2

1:54 pm-8:41 pm

1 stop7h 47m

$437

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 2/14

7:10 am-2:15 pm

1 stop6h 05m

George Town Owen Roberts Intl

Sat 2/21

3:56 pm-11:23 pm

1 stop8h 27m

$437

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Wed 1/28

4:05 pm-12:25 pm

1 stop19h 20m

George Town Owen Roberts Intl

Tue 2/24

1:30 pm-3:29 pm

1 stop26h 59m

$438

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 1/31

4:05 pm-12:25 pm

1 stop19h 20m

George Town Owen Roberts Intl

Tue 2/24

1:30 pm-3:29 pm

1 stop26h 59m

$449

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 1/31

4:05 pm-12:25 pm

1 stop19h 20m

George Town Owen Roberts Intl

Thu 2/19

1:30 pm-3:29 pm

1 stop26h 59m

$459

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 2/14

6:00 am-4:20 pm

1 stop9h 20m

George Town Owen Roberts Intl

Sat 2/21

5:45 pm-10:36 am

2 stops17h 51m

$512

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 2/23

9:36 am-8:15 pm

2 stops9h 39m

$106

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/18

Showing 1-10 of 18 results
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2

Best time to book a flight from St. Louis to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to the Cayman Islands

What is the cheapest month to book a flight from St. Louis to Cayman Islands?

Currently, April is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $258). Flying from St. Louis to Cayman Islands in March is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated January 20, 2026.
Read through reviews of airlines operating flights from St. Louis to the Cayman Islands, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,076 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,180 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,164 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Cayman Islands?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Cayman Islands from St. Louis.

  • How long is the flight from St. Louis to Cayman Islands?

    Airlines like American Airlines and Delta fly from St. Louis to Cayman Islands in about 7h 30m. The time it takes to get you to your destination can typically vary by up to 9h 09m. The distance between St. Louis and Cayman Islands is about 1448 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from St. Louis to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cayman Islands.

  • Can I find deals for business class flights from St. Louis to Cayman Islands?

    Yes. Cheapflights offers flight deals from St. Louis to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Cayman Islands?

    Currently, April is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $258). Flying from St. Louis to Cayman Islands in March is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from St. Louis to Cayman Islands

Discover the top 4 airlines that operate flights from St. Louis to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$605FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$365Average$698FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$429Average$595FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$458Average$624FlexibilityNo cancel feeOn-time71%

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