Cayman Islands

$131+ Cheap flights from St. Louis (STL) to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Feb 7 — Feb 141
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Cheap flight deals from St. Louis to Cayman Islands

Keep the following information in mind while searching for St. Louis to Cayman Islands flight deals. Data was last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$361
(Air Canada)

One-way from

$131
(Delta)

Popular in

March

Cheapest in

September

Average price

$571
Provider with most accurate pricing for Lambert-St Louis-George Town Owen Roberts Intl flight deals.
Provider most trusted by Cheapflights users for Lambert-St Louis-George Town Owen Roberts Intl flights.
From Lambert-St Louis to Cayman Islands
One-way flight from Lambert-St Louis to Cayman Islands
Highest demand for flights based on searches. 9% potential increase in price ($66 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Average for round-trip flights in January 2026

Find flight deals from St. Louis to Cayman Islands

Cheapest flights from St. Louis to Cayman Islands
Explore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Air Canada deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:05 pmSTL - GCM
1 stop19h 05mAir Canada
Sat 5/212:25 pmGCM - STL
1 stop7h 39mAir Canada
Deal found 1/7$361
This Air Canada deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/104:05 pmSTL - GCM
1 stop19h 20mAir Canada
Tue 1/131:30 pmGCM - STL
1 stop26h 59mAir Canada
Deal found 1/6$380
This Delta deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:00 amSTL - GCM
1 stop5h 24mDelta
Mon 4/2712:45 pmGCM - STL
1 stop10h 48mDelta
Deal found 1/6$392
This Air Canada deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/54:05 pmSTL - GCM
1 stop19h 20mAir Canada
Mon 2/91:30 pmGCM - STL
1 stop26h 59mAir Canada
Deal found 1/7$395
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 amSTL - GCM
1 stop6h 30mUnited Airlines
Tue 4/281:35 pmGCM - STL
2 stops19h 00mUnited Airlines
Deal found 1/8$448
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:25 amSTL - GCM
1 stop6h 20mUnited Airlines
Fri 2/202:50 pmGCM - STL
1 stop7h 50mUnited Airlines
Deal found 1/7$462
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:11 pmSTL - GCM
2 stops17h 21mAmerican Airlines
Sat 5/22:10 pmGCM - STL
2 stops9h 38mAmerican Airlines
Deal found 1/7$467
This American Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:54 pmSTL - GCM
2 stops18h 17mAmerican Airlines
Tue 4/2812:00 pmGCM - STL
2 stops20h 28mAmerican Airlines
Deal found 1/8$473
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:54 pmSTL - GCM
2 stops18h 17mAmerican Airlines
Mon 4/2712:00 pmGCM - STL
1 stop10h 24mAmerican Airlines
Deal found 1/6$492
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:40 amSTL - GCM
1 stop6h 50mUnited Airlines
Thu 5/211:35 pmGCM - STL
1 stop8h 31mUnited Airlines
Deal found 1/7$514

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from St. Louis to the Cayman Islands that are best for you.

Fly from

St. Louis

Fly to

Cayman Islands

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Thu 4/23

4:05 pm-11:10 am

1 stop19h 05m

George Town Owen Roberts Intl

Tue 4/28

12:30 pm-3:24 pm

1 stop26h 54m

$361

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/18

4:05 pm-11:10 am

1 stop19h 05m

George Town Owen Roberts Intl

Sat 5/2

12:25 pm-8:04 pm

1 stop7h 39m

$361

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Wed 4/22

6:00 am-11:24 am

1 stop5h 24m

George Town Owen Roberts Intl

Mon 4/27

12:45 pm-11:33 pm

1 stop10h 48m

$392

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Thu 4/23

6:00 am-12:30 pm

1 stop6h 30m

George Town Owen Roberts Intl

Tue 4/28

1:35 pm-8:35 am

2 stops19h 00m

$448

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 2/16

6:25 am-1:45 pm

1 stop6h 20m

George Town Owen Roberts Intl

Fri 2/20

2:50 pm-9:40 pm

1 stop7h 50m

$462

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/18

6:11 pm-11:32 am

2 stops17h 21m

George Town Owen Roberts Intl

Sat 5/2

4:03 pm-8:57 am

2 stops16h 54m

$467

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 2/23

6:00 am-12:29 pm

1 stop5h 29m

$131

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 2/22

6:00 am-12:29 pm

1 stop5h 29m

$131

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 2/23

8:22 pm-4:05 pm

2 stops18h 43m

$165

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 2/23

6:00 am-8:15 pm

2 stops13h 15m

$226

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Showing 1-10 of 14 results
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Best time to book a flight from St. Louis to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to the Cayman Islands

What is the cheapest month to book a flight from St. Louis to Cayman Islands?

Currently, April is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $241). Flying from St. Louis to Cayman Islands in June is currently the most expensive (average of $499). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated January 8, 2026.
Read through reviews of airlines operating flights from St. Louis to the Cayman Islands, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Crew

8.6

Food

7.0

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Boarding

8.1

Crew

8.6

Food

7.0

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Boarding

8.1

Crew

8.6

Food

7.0

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Boarding

8.1

Crew

8.6

Food

7.0

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Boarding

8.1

Crew

8.6

Food

7.0

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from St. Louis to Cayman Islands?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Cayman Islands from St. Louis.

  • How long is the flight from St. Louis to Cayman Islands?

    Airlines like Air Canada fly from St. Louis to Cayman Islands in about 19h 05m. The time it takes to get you to your destination can typically vary by up to . The distance between St. Louis and Cayman Islands is about 1448 mi.

  • Can I find deals for flights from St. Louis to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cayman Islands.

  • Can I find deals for business class flights from St. Louis to Cayman Islands?

    Yes. Cheapflights offers flight deals from St. Louis to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Cayman Islands?

    Currently, April is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $241). Flying from St. Louis to Cayman Islands in June is currently the most expensive (average of $499). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from St. Louis to Cayman Islands

Discover the top 4 airlines that operate flights from St. Louis to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$605FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$365Average$730FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$429Average$581FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$439Average$612FlexibilityNo cancel feeOn-time71%

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