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Cayman Islands

$446+ Cheap flights from St. Louis (STL) to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from St. Louis to Cayman Islands

Keep the following information in mind while searching for St. Louis to Cayman Islands flight deals. Data was last updated September 15, 2025.

Round-trip from

$446
(Delta)

Popular in

March

Cheapest in

September

Average price

$468
From Lambert-St Louis to Cayman Islands
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($56 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from St. Louis to Cayman Islands

Cheapest flights from St. Louis to Cayman Islands
Explore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2112:51 pmSTL - GCM
1 stop22h 29mAmerican Airlines
Tue 10/2812:25 pmGCM - STL
1 stop10h 40mAmerican Airlines
Deal found 9/14$447
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:52 amSTL - GCM
1 stop6h 18mAmerican Airlines
Wed 11/121:20 pmGCM - STL
1 stop10h 07mAmerican Airlines
Deal found 9/15$460
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/185:20 amSTL - GCM
1 stop6h 05mAmerican Airlines
Sat 10/258:25 amGCM - STL
1 stop15h 31mAmerican Airlines
Deal found 9/15$474
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:00 amSTL - GCM
1 stop5h 35mDelta
Mon 10/2712:55 pmGCM - STL
1 stop10h 46mDelta
Deal found 9/14$536
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:00 amSTL - GCM
1 stop5h 35mDelta
Mon 10/2712:55 pmGCM - STL
1 stop10h 46mDelta
Deal found 9/14$538
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/195:23 amSTL - GCM
1 stop5h 47mAmerican Airlines
Fri 10/3112:25 pmGCM - STL
1 stop6h 21mAmerican Airlines
Deal found 9/14$540

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from St. Louis to the Cayman Islands that are best for you.

Fly from

St. Louis

Fly to

Cayman Islands

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Wed 1/28

2:00 pm-11:40 pm

1 stop10h 40m

$446

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 11/7

6:52 am-2:10 pm

1 stop6h 18m

George Town Owen Roberts Intl

Wed 11/12

1:20 pm-11:07 pm

2 stops10h 47m

$464

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 2/20

6:45 am-1:45 pm

1 stop6h 00m

George Town Owen Roberts Intl

Fri 2/27

2:50 pm-9:00 pm

1 stop7h 10m

$501

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

7:05 pm-11:00 am

1 stop14h 55m

George Town Owen Roberts Intl

Thu 1/29

2:00 pm-8:39 pm

1 stop7h 39m

$501

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

7:05 pm-11:00 am

1 stop14h 55m

George Town Owen Roberts Intl

Tue 2/3

2:00 pm-11:40 pm

1 stop10h 40m

$501

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

7:05 pm-12:50 pm

2 stops16h 45m

George Town Owen Roberts Intl

Fri 1/30

3:45 pm-11:10 pm

1 stop8h 25m

$505

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 1/24

7:30 am-1:47 pm

1 stop5h 17m

George Town Owen Roberts Intl

Thu 1/29

2:00 pm-8:39 pm

1 stop7h 39m

$530

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 2/20

9:39 am-7:51 pm

2 stops9h 12m

George Town Owen Roberts Intl

Fri 2/27

2:00 pm-9:44 pm

1 stop8h 44m

$549

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 10/19

6:15 am-12:30 pm

1 stop6h 15m

George Town Owen Roberts Intl

Mon 10/27

4:45 pm-3:47 pm

2 stops23h 02m

$550

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 3/10

6:00 am-11:35 am

1 stop5h 35m

George Town Owen Roberts Intl

Wed 3/11

1:00 pm-8:39 pm

1 stop7h 39m

$556

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from St. Louis to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to the Cayman Islands

What is the cheapest month to book a flight from St. Louis to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $467). Flying from St. Louis to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated September 15, 2025.
Read through reviews of airlines operating flights from St. Louis to the Cayman Islands, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,929 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Cayman Islands?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Cayman Islands from St. Louis.

  • How long is the flight from St. Louis to Cayman Islands?

    Airlines like Delta, American Airlines, and United Airlines fly from St. Louis to Cayman Islands in about 5h 35m. The time it takes to get you to your destination can typically vary by up to 43m. The distance between St. Louis and Cayman Islands is about 1448 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from St. Louis to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cayman Islands.

  • Can I find deals for business class flights from St. Louis to Cayman Islands?

    Yes. Cheapflights offers flight deals from St. Louis to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $467). Flying from St. Louis to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from St. Louis to Cayman Islands

Discover the top 4 airlines that operate flights from St. Louis to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$605FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$429Average$585FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$439Average$611FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$698FlexibilityNo cancel feeOn-time69%

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