Cayman Islands

$131+ Cheap flights from St. Louis (STL) to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
May 7 — May 141
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Cayman Islands with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from St. Louis to Cayman Islands

Cheapest flights from St. Louis to Cayman Islands
Explore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.

This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
STL
-
GCM
1 stop6h 30m
United Airlines
Tue 5/51:35 pm
GCM
-
STL
1 stop8h 55m
United Airlines
Deal found 4/5$461
This Air Canada deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:05 pm
STL
-
GCM
1 stop18h 50m
Air Canada
Sat 5/210:55 am
GCM
-
STL
1 stop9h 14m
Air Canada
Deal found 4/6$463
This Air Canada deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:55 am
STL
-
GCM
1 stop26h 30m
Air Canada
Sat 8/810:40 am
GCM
-
STL
1 stop9h 27m
Air Canada
Deal found 4/3$465
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:24 am
STL
-
GCM
1 stop7h 46m
American Airlines
Wed 5/1312:00 pm
GCM
-
STL
2 stops10h 19m
American Airlines
Deal found 4/6$471
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:54 pm
STL
-
GCM
2 stops16h 06m
American Airlines
Fri 5/2212:33 pm
GCM
-
STL
1 stop6h 27m
American Airlines
Deal found 4/3$525
This Orbitz deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/288:40 am
STL
-
GCM
1 stop26h 45m
Air Canada
Sat 7/410:55 am
GCM
-
STL
1 stop9h 12m
Air Canada
Deal found 4/6$545
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:30 pm
STL
-
GCM
2 stops17h 40m
Southwest
Tue 5/261:05 pm
GCM
-
STL
2 stops19h 55m
Southwest
Deal found 4/4$556

Find flight deals from St. Louis to Cayman Islands

Keep the following information in mind while searching for St. Louis to Cayman Islands flight deals. Data was last updated April 7, 2026.

Round-trip from

$461
(United Airlines)

One-way from

$131
(Air Canada)

Popular in

December

Cheapest in

September

Average price

$497
From Lambert-St Louis to Cayman Islands
One-way flight from Lambert-St Louis to Cayman Islands
Highest demand for flights based on searches. 0% potential increase in price ($5 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from St. Louis to the Cayman Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/18

4:05 pm-10:55 am

1 stop18h 50m

George Town Owen Roberts Intl

Sat 5/2

10:55 am-12:06 pm

1 stop25h 11m

$463

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Thu 4/30

6:00 am-12:30 pm

1 stop6h 30m

George Town Owen Roberts Intl

Tue 5/5

1:35 pm-8:39 am

2 stops19h 04m

$466

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 5/19

5:30 am-12:10 pm

1 stop6h 40m

George Town Owen Roberts Intl

Tue 5/26

1:05 pm-9:00 am

2 stops19h 55m

$525

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/25

6:00 am-12:00 pm

1 stop6h 00m

George Town Owen Roberts Intl

Wed 4/29

1:25 pm-11:36 pm

1 stop10h 11m

$564

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/25

6:30 am-1:30 pm

1 stop7h 00m

George Town Owen Roberts Intl

Wed 4/29

1:35 pm-8:39 am

2 stops19h 04m

$569
Quickest round-trip

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 5/29

6:00 am-11:54 am

1 stop5h 54m

George Town Owen Roberts Intl

Wed 6/3

1:19 pm-9:38 pm

1 stop8h 19m

$579

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 5/4

6:00 am-12:30 pm

1 stop6h 30m

George Town Owen Roberts Intl

Wed 5/6

1:35 pm-10:30 pm

1 stop8h 55m

$581

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 7/26

7:55 pm-11:25 am

2 stops15h 30m

George Town Owen Roberts Intl

Wed 7/29

12:02 pm-11:32 pm

2 stops11h 30m

$584
Cheapest one-way

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 5/15

7:05 am-10:00 am

1 stop26h 55m

$131
Quickest one-way

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 5/15

8:30 pm-12:30 pm

2 stops16h 00m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/2

Sorted by cheapest first

Best time to book a flight from St. Louis to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to the Cayman Islands

What is the cheapest month to book a flight from St. Louis to Cayman Islands?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $248). Flying from St. Louis to Cayman Islands in June is currently the most expensive (average of $570). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated April 7, 2026.
Read through reviews of airlines operating flights from St. Louis to the Cayman Islands, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from St. Louis to Cayman Islands?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Cayman Islands from St. Louis.

  • How long is the flight from St. Louis to Cayman Islands?

    Airlines like United Airlines and Air Canada fly from St. Louis to Cayman Islands in about 6h 30m. The time it takes to get you to your destination can typically vary by up to 12h 20m. The distance between St. Louis and Cayman Islands is about 1448 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from St. Louis to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cayman Islands.

  • Can I find deals for business class flights from St. Louis to Cayman Islands?

    Yes. Cheapflights offers flight deals from St. Louis to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Cayman Islands?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $248). Flying from St. Louis to Cayman Islands in June is currently the most expensive (average of $570). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from St. Louis to Cayman Islands

Discover the top 4 airlines that operate flights from St. Louis to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$190Average$597FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$364Average$625FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$424Average$622FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$429Average$578FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.