HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cayman Islands

$146+ Cheap flights from St. Louis (STL) to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Cayman Islands with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from St. Louis to Cayman Islands

Cheapest flights from St. Louis to Cayman Islands
Explore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Air Canada deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/194:05 pmSTL - GCM
1 stop19h 20mAir Canada
Tue 12/21:30 pmGCM - STL
1 stop26h 59mAir Canada
Deal found 11/5$425
This Air Canada deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/194:05 pmSTL - GCM
1 stop19h 20mAir Canada
Thu 11/271:30 pmGCM - STL
1 stop26h 59mAir Canada
Deal found 11/5$435
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/278:20 amSTL - GCM
1 stop7h 10mUnited Airlines
Mon 12/15:45 pmGCM - STL
2 stops22h 55mUnited Airlines
Deal found 11/5$489
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:42 pmSTL - GCM
2 stops20h 48mUnited Airlines
Thu 12/115:45 pmGCM - STL
2 stops19h 30mUnited Airlines
Deal found 11/6$505
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amSTL - GCM
1 stop5h 35mDelta
Thu 12/111:50 pmGCM - STL
1 stop10h 52mDelta
Deal found 11/6$509
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:00 amSTL - GCM
1 stop9h 00mUnited Airlines
Sun 12/285:45 pmGCM - STL
2 stops19h 42mUnited Airlines
Deal found 11/6$514
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:08 pmSTL - GCM
1 stop20h 49mAmerican Airlines
Fri 11/143:10 pmGCM - STL
1 stop8h 57mAmerican Airlines
Deal found 11/5$518
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:00 amSTL - GCM
1 stop5h 35mDelta
Wed 11/121:50 pmGCM - STL
1 stop9h 08mDelta
Deal found 11/6$548

Cheap flight deals from St. Louis to Cayman Islands

Keep the following information in mind while searching for St. Louis to Cayman Islands flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$425
(Air Canada)

One-way from

$146
(Air Canada)

Popular in

March

Cheapest in

September

Average price

$544
Provider with most accurate pricing for Lambert-St Louis-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-George Town Owen Roberts Intl flights.
Search Deals
From Lambert-St Louis to Cayman Islands
Search Deals
One-way flight from Lambert-St Louis to Cayman Islands
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($65 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from St. Louis to the Cayman Islands that are best for you.

Fly from

St. Louis

Fly to

Cayman Islands

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 3/10

6:00 am-11:35 am

1 stop5h 35m

George Town Owen Roberts Intl

Wed 3/11

1:00 pm-7:14 pm

1 stop6h 14m

$484

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 2/22

6:30 am-1:45 pm

1 stop6h 15m

George Town Owen Roberts Intl

Thu 2/26

2:50 pm-10:00 pm

1 stop8h 10m

$484

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sun 2/22

6:15 pm-12:55 pm

2 stops17h 40m

George Town Owen Roberts Intl

Thu 2/26

1:50 pm-11:25 pm

1 stop10h 35m

$489

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 12/1

6:15 am-4:30 pm

1 stop9h 15m

George Town Owen Roberts Intl

Fri 12/5

5:45 pm-2:25 pm

2 stops21h 40m

$489

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Thu 11/27

8:20 am-4:30 pm

1 stop7h 10m

George Town Owen Roberts Intl

Mon 12/1

5:45 pm-3:40 pm

2 stops22h 55m

$489

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 1/13

7:00 am-8:25 pm

1 stop12h 25m

George Town Owen Roberts Intl

Mon 1/26

12:16 pm-6:34 pm

1 stop7h 18m

$509

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 1/3

5:05 am-3:10 pm

1 stop9h 05m

George Town Owen Roberts Intl

Thu 1/8

1:50 pm-9:25 pm

1 stop8h 35m

$509

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 12/19

6:30 am-1:45 pm

1 stop6h 15m

George Town Owen Roberts Intl

Sat 12/27

5:45 pm-12:27 pm

2 stops19h 42m

$561

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 11/25

6:00 am-12:35 pm

1 stop5h 35m

George Town Owen Roberts Intl

Thu 11/27

1:50 pm-9:58 pm

1 stop9h 08m

$564

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 3/10

5:28 am-1:19 pm

1 stop7h 51m

George Town Owen Roberts Intl

Wed 3/11

3:15 pm-9:22 am

2 stops18h 07m

$599

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 19 results
1
2

Best time to book a flight from St. Louis to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to the Cayman Islands

What is the cheapest month to book a flight from St. Louis to Cayman Islands?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $267). Flying from St. Louis to Cayman Islands in December is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated November 6, 2025.
Read through reviews of airlines operating flights from St. Louis to the Cayman Islands, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,007 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,040 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Cayman Islands?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Cayman Islands from St. Louis.

  • How long is the flight from St. Louis to Cayman Islands?

    Airlines like Delta, United Airlines, and Southwest fly from St. Louis to Cayman Islands in about 5h 35m. The time it takes to get you to your destination can typically vary by up to 12h 05m. The distance between St. Louis and Cayman Islands is about 1448 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from St. Louis to Cayman Islands one-way?

    The cheapest airlines for a one-way flight from St. Louis to Cayman Islands are Air Canada ($146), Delta ($270), and United Airlines ($325).

  • Can I find deals for flights from St. Louis to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cayman Islands.

  • Can I find deals for business class flights from St. Louis to Cayman Islands?

    Yes. Cheapflights offers flight deals from St. Louis to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Cayman Islands?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $267). Flying from St. Louis to Cayman Islands in December is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Luis Munoz Marin Intl flights
Kansas City to Luis Munoz Marin Intl flights
St. Louis to Punta Cana flights
Kansas City to Punta Cana flights
Kansas City to Saint Thomas Island flights
St. Louis to Oranjestad flights
Kansas City to George Town flights
St. Louis to Saint Thomas Island flights
Kansas City to Montego Bay flights
St. Louis to Montego Bay flights
Kansas City to Santo Domingo flights
Springfield to Luis Munoz Marin Intl flights
St. Louis to Simpson Bay flights
St. Louis to Georgetown flights
St. Louis to Castries flights
St. Louis to Nassau flights
Kansas City to Providenciales flights
Kansas City to Castries flights
Kansas City to Oranjestad flights
St. Louis to Bridgetown flights
Kansas City to Nassau flights
St. Louis to Santo Domingo flights
Kansas City to Simpson Bay flights
St. Louis to Willemstad flights
Springfield to Oranjestad flights
Kansas City to Willemstad flights
Kansas City to Christiansted flights
St. Louis to Christiansted flights
Kansas City to Gregory Town flights
St. Louis to Kralendijk flights
St. Louis to Kingston flights
Kansas City to Kingston flights
Springfield to Punta Cana flights
St. Louis to Providenciales flights
St. Louis to George Town flights
St. Louis to Santiago de los Caballeros flights
St. Louis to St. John's flights
Kansas City to Puerto Plata flights
St. Louis to Basseterre flights
Kansas City to Santiago de los Caballeros flights
St. Louis to Puerto Plata flights
Kansas City to St. John's flights
Kansas City to Road Town flights
Kansas City to The Valley flights
Springfield to Montego Bay flights
Kansas City to Bridgetown flights
St. Louis to St. George's flights
Kansas City to Marsh Harbour flights
Springfield to Nassau flights
Kansas City to Basseterre flights

Top 4 airlines flying from St. Louis to Cayman Islands

Discover the top 4 airlines that operate flights from St. Louis to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$266Average$613FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$424Average$607FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$429Average$581FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$469Average$698FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.