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Cayman Islands

$337+ Cheap flights from St. Louis (STL) to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from St. Louis to Cayman Islands

Cheapest flights from St. Louis to Cayman Islands
Explore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:00 amSTL - GCM
1 stop5h 35mDelta
Thu 12/181:50 pmGCM - STL
1 stop9h 07mDelta
Deal found 11/11$346
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:58 pmSTL - GCM
1 stop16h 31mAmerican Airlines
Thu 12/183:45 pmGCM - STL
2 stops17h 50mAmerican Airlines
Deal found 11/11$351
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:00 amSTL - GCM
1 stop5h 35mDelta
Thu 11/201:50 pmGCM - STL
1 stop10h 54mDelta
Deal found 11/12$384
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:30 amSTL - GCM
2 stops9h 00mUnited Airlines
Wed 11/195:45 pmGCM - STL
2 stops21h 39mUnited Airlines
Deal found 11/12$389
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:15 amSTL - GCM
1 stop14h 13mAmerican Airlines
Sun 11/163:10 pmGCM - STL
1 stop9h 55mAmerican Airlines
Deal found 11/11$534
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:24 pmSTL - GCM
2 stops21h 56mUnited Airlines
Sun 11/165:45 pmGCM - STL
2 stops47h 02mUnited Airlines
Deal found 11/11$556
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/226:00 amSTL - GCM
1 stop5h 25mDelta
Thu 11/271:50 pmGCM - STL
1 stop9h 08mDelta
Deal found 11/12$591
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:27 pmSTL - GCM
3 stops22h 08mUnited Airlines
Thu 12/185:45 pmGCM - STL
2 stops19h 42mUnited Airlines
Deal found 11/11$595
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/237:03 pmSTL - GCM
2 stops16h 21mAmerican Airlines
Thu 11/271:25 pmGCM - STL
1 stop10h 09mAmerican Airlines
Deal found 11/12$626
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/205:00 amSTL - GCM
1 stop8h 14mAmerican Airlines
Fri 11/283:10 pmGCM - STL
1 stop9h 55mAmerican Airlines
Deal found 11/12$643

Cheap flight deals from St. Louis to Cayman Islands

Keep the following information in mind while searching for St. Louis to Cayman Islands flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$337
(Delta)

Popular in

March

Cheapest in

September

Average price

$544
Provider with most accurate pricing for Lambert-St Louis-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-George Town Owen Roberts Intl flights.
Search Deals
From Lambert-St Louis to Cayman Islands
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from St. Louis to the Cayman Islands that are best for you.

Fly from

St. Louis

Fly to

Cayman Islands

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Wed 1/28

2:05 pm-11:39 pm

1 stop10h 34m

$337

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

6:10 am-2:40 pm

1 stop7h 30m

George Town Owen Roberts Intl

Mon 2/2

2:05 pm-11:39 pm

1 stop10h 34m

$337

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

6:10 am-2:40 pm

1 stop7h 30m

George Town Owen Roberts Intl

Tue 2/3

2:05 pm-11:39 pm

1 stop10h 34m

$337

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 1/24

7:10 am-2:00 pm

1 stop5h 50m

George Town Owen Roberts Intl

Sat 1/31

2:05 pm-7:27 pm

1 stop6h 22m

$337

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Tue 2/3

2:05 pm-8:39 pm

1 stop7h 34m

$337

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 1/24

6:00 am-2:00 pm

1 stop7h 00m

George Town Owen Roberts Intl

Thu 1/29

2:05 pm-8:39 pm

1 stop7h 34m

$337

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Thu 1/29

2:05 pm-8:39 pm

1 stop7h 34m

$337

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

5:56 pm-11:19 am

1 stop16h 23m

George Town Owen Roberts Intl

Sat 1/31

2:05 pm-7:27 pm

1 stop6h 22m

$337

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Sat 1/31

2:05 pm-7:27 pm

1 stop6h 22m

$346

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 3/10

6:00 am-11:35 am

1 stop5h 35m

George Town Owen Roberts Intl

Wed 3/11

1:00 pm-7:14 pm

1 stop6h 14m

$346

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 11 results
1
2

Best time to book a flight from St. Louis to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to the Cayman Islands

What is the cheapest month to book a flight from St. Louis to Cayman Islands?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $267). Flying from St. Louis to Cayman Islands in December is currently the most expensive (average of $553). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated November 13, 2025.
Read through reviews of airlines operating flights from St. Louis to the Cayman Islands, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,007 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,017 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,051 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Cayman Islands?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Cayman Islands from St. Louis.

  • How long is the flight from St. Louis to Cayman Islands?

    Airlines like Delta fly from St. Louis to Cayman Islands in about 5h 40m. The time it takes to get you to your destination can typically vary by up to . The distance between St. Louis and Cayman Islands is about 1448 mi.

  • Can I find deals for flights from St. Louis to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cayman Islands.

  • Can I find deals for business class flights from St. Louis to Cayman Islands?

    Yes. Cheapflights offers flight deals from St. Louis to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Cayman Islands?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $267). Flying from St. Louis to Cayman Islands in December is currently the most expensive (average of $553). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from St. Louis to Cayman Islands

Discover the top 4 airlines that operate flights from St. Louis to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$266Average$613FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$424Average$607FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$429Average$581FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$469Average$698FlexibilityNo cancel feeOn-time69%

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