How long is the flight from St. Louis to Cayman Islands?

Airlines like Delta fly from St. Louis to Cayman Islands in about 5h 40m. The time it takes to get you to your destination can typically vary by up to . The distance between St. Louis and Cayman Islands is about 1448 mi.

What are the most popular airlines that fly from St. Louis to Cayman Islands?

Before booking your flight from St. Louis to Cayman Islands check out the most popular airlines for this route: American Airlines, Delta or United Airlines.

What is the cheapest time of day to fly from STL to KY?

When flying from St. Louis to Cayman Islands, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly from for flights from St. Louis to Cayman Islands?

Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Cayman Islands from St. Louis.

Can I find deals for flights from St. Louis to Cayman Islands that include hotel bookings?

Yes. In addition to deals on St. Louis to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Cayman Islands?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cayman Islands.

Can I find deals for business class flights from St. Louis to Cayman Islands?

Yes. Cheapflights offers flight deals from St. Louis to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$352+ Flights from St. Louis to the Cayman Islands

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Cheap flight deals from St. Louis to Cayman Islands

Cheapest flights from St. Louis to Cayman Islands
Explore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Thu 12/116:30 amSTL - GCM

2 stops9h 00mUnited Airlines

Thu 12/185:45 pmGCM - STL

1 stop17h 04mUnited Airlines

Deal found 12/10

$360

Thu 12/116:00 amSTL - GCM

2 stops13h 15mAmerican Airlines

Thu 12/183:45 pmGCM - STL

2 stops17h 50mAmerican Airlines

Deal found 12/10

$395

Best flights from St. Louis to Cayman Islands
Discover carefully curated flight deals from St. Louis to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Mon 1/266:00 amSTL - GCM

1 stop5h 40mDelta

Tue 2/32:05 pmGCM - STL

1 stop7h 32mDelta

Deal found 12/10

$352

Thu 1/86:30 amSTL - GCM

1 stop6h 15mUnited Airlines

Thu 1/152:25 pmGCM - STL

1 stop10h 34mUnited Airlines

Deal found 12/9

$375

Thu 1/88:13 amSTL - GCM

2 stops11h 07mAmerican Airlines

Thu 1/153:45 pmGCM - STL

2 stops18h 06mAmerican Airlines

Deal found 12/9

$388

Wed 1/286:00 amSTL - GCM

1 stop5h 40mDelta

Tue 2/32:05 pmGCM - STL

1 stop7h 32mDelta

Deal found 12/10

$352

Tue 1/276:52 amSTL - GCM

2 stops12h 28mAmerican Airlines

Tue 2/31:05 pmGCM - STL

2 stops10h 54mAmerican Airlines

Deal found 12/10

$398

Fri 1/233:45 pmSTL - GCM

2 stops20h 05mDelta

Tue 2/32:05 pmGCM - STL

1 stop10h 32mDelta

Deal found 12/10

$375

Mon 1/266:00 amSTL - GCM

1 stop5h 40mDelta

Mon 2/22:05 pmGCM - STL

1 stop7h 32mDelta

Deal found 12/10

$375

Sat 1/246:00 amSTL - GCM

1 stop5h 40mDelta

Tue 2/32:05 pmGCM - STL

1 stop7h 32mDelta

Deal found 12/10

$375

Wed 1/286:00 amSTL - GCM

1 stop5h 40mDelta

Sat 1/312:05 pmGCM - STL

1 stop6h 22mDelta

Deal found 12/10

$375

Sat 1/316:00 amSTL - GCM

1 stop7h 00mDelta

Fri 2/131:54 pmGCM - STL

1 stop10h 42mDelta

Deal found 12/9

$383

Sat 1/246:00 amSTL - GCM

1 stop7h 00mDelta

Sat 1/312:05 pmGCM - STL

1 stop6h 22mDelta

Deal found 12/10

$398

Fri 1/235:32 pmSTL - GCM

1 stop18h 18mDelta

Sat 1/312:05 pmGCM - STL

1 stop6h 22mDelta

Deal found 12/10

$398

Last-minute flights from St. Louis to Cayman Islands
Discover last-minute flight deals from St. Louis to Cayman Islands. Data last updated December 12, 2025 and is based on user searches.

Thu 12/116:30 amSTL - GCM

2 stops9h 00mUnited Airlines

Thu 12/185:45 pmGCM - STL

1 stop17h 04mUnited Airlines

Deal found 12/10

$360

Thu 12/116:00 amSTL - GCM

2 stops13h 15mAmerican Airlines

Thu 12/183:45 pmGCM - STL

2 stops17h 50mAmerican Airlines

Deal found 12/10

$395

Tue 1/66:00 amSTL - GCM

1 stop5h 40mDelta

Sat 1/103:25 pmGCM - STL

1 stop9h 14mDelta

Deal found 12/11

$383

Thu 1/88:13 amSTL - GCM

2 stops11h 07mAmerican Airlines

Thu 1/153:45 pmGCM - STL

2 stops18h 06mAmerican Airlines

Deal found 12/9

$388

Sat 1/106:00 amSTL - GCM

1 stop9h 20mUnited Airlines

Sun 1/182:50 pmGCM - STL

1 stop7h 23mUnited Airlines

Deal found 12/10

$406

Fri 1/235:32 pmSTL - GCM

1 stop18h 18mDelta

Tue 2/32:05 pmGCM - STL

1 stop10h 32mDelta

Deal found 12/10

$375

Sat 1/244:05 pmSTL - GCM

1 stop19h 20mAir Canada

Thu 1/291:30 pmGCM - STL

1 stop26h 59mAir Canada

Deal found 12/10

$391

Sat 1/246:00 amSTL - GCM

1 stop7h 00mDelta

Sat 1/312:05 pmGCM - STL

1 stop6h 22mDelta

Deal found 12/10

$398

Mon 1/266:00 amSTL - GCM

1 stop5h 40mDelta

Tue 2/32:05 pmGCM - STL

1 stop7h 32mDelta

Deal found 12/10

$352

Sat 1/315:04 pmSTL - GCM

2 stops17h 46mAmerican Airlines

Mon 2/163:45 pmGCM - STL

1 stop19h 41mAmerican Airlines

Deal found 12/9

$399

Find flight deals from St. Louis to Cayman Islands

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$352 (Delta)
Popular in	March
Cheapest in	September
Average price	$662

Provider with most accurate pricing for Lambert-St Louis-George Town Owen Roberts Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-George Town Owen Roberts Intl flights.

Search Deals

From Lambert-St Louis to Cayman Islands

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($69 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to the Cayman Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Tue 2/3

2:05 pm-8:37 pm

1 stop7h 32m

$352

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Wed 1/28

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Tue 2/3

2:05 pm-8:37 pm

1 stop7h 32m

$352

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Thu 1/8

6:30 am-1:45 pm

1 stop6h 15m

George Town Owen Roberts Intl

Thu 1/15

2:25 pm-11:59 pm

1 stop10h 34m

$375

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Fri 1/23

3:45 pm-12:50 pm

2 stops20h 05m

George Town Owen Roberts Intl

Tue 2/3

2:05 pm-11:37 pm

1 stop10h 32m

$375

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 1/26

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Mon 2/2

2:05 pm-8:37 pm

1 stop7h 32m

$375

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 1/24

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Tue 2/3

2:05 pm-8:37 pm

1 stop7h 32m

$375

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Wed 1/28

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Sat 1/31

2:05 pm-7:27 pm

1 stop6h 22m

$375

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 1/31

6:00 am-2:00 pm

1 stop7h 00m

George Town Owen Roberts Intl

Fri 2/13

1:54 pm-11:36 pm

1 stop10h 42m

$383

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Thu 1/8

8:13 am-8:20 pm

2 stops11h 07m

George Town Owen Roberts Intl

Thu 1/15

3:45 pm-8:51 am

2 stops18h 06m

$388

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Tue 1/27

6:52 am-8:20 pm

2 stops12h 28m

George Town Owen Roberts Intl

Tue 2/3

1:05 pm-10:59 pm

2 stops10h 54m

$398

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 12 results

Best time to book a flight from St. Louis to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to the Cayman Islands

What is the cheapest month to book a flight from St. Louis to Cayman Islands?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $267). Flying from St. Louis to Cayman Islands in December is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Read through reviews of airlines operating flights from St. Louis to the Cayman Islands, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,253 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,008 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,095 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,050 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airport do you fly from for flights from St. Louis to Cayman Islands?
Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to Cayman Islands from St. Louis.
How long is the flight from St. Louis to Cayman Islands?
Airlines like Delta fly from St. Louis to Cayman Islands in about 5h 40m. The time it takes to get you to your destination can typically vary by up to . The distance between St. Louis and Cayman Islands is about 1448 mi.
Can I find deals for flights from St. Louis to Cayman Islands that include hotel bookings?
Yes. In addition to deals on St. Louis to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Cayman Islands?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cayman Islands.
Can I find deals for business class flights from St. Louis to Cayman Islands?
Yes. Cheapflights offers flight deals from St. Louis to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Cayman Islands?
Currently, August is the cheapest month in which you can book a flight from St. Louis to Cayman Islands (average of $267). Flying from St. Louis to Cayman Islands in December is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from St. Louis to Cayman Islands

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$266	Average$613	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$424	Average$606	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$429	Average$581	FlexibilityNo cancel fee	On-time63%
United Airlines	Cheapest$469	Average$724	FlexibilityNo cancel fee	On-time69%

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$352+ Cheap flights from St. Louis (STL) to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Cayman Islands with Cheapflights

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Cheap flight deals from St. Louis to Cayman Islands

Cheapest flights from St. Louis to Cayman IslandsExplore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from St. Louis to Cayman Islands

Keep the following information in mind while searching for St. Louis to Cayman Islands flight deals. Data was last updated December 12, 2025.

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to the Cayman Islands that are best for you.

Best time to book a flight from St. Louis to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to the Cayman Islands

What is the cheapest month to book a flight from St. Louis to Cayman Islands?

Reviews of airlines servicing Cayman Islands

Read through reviews of airlines operating flights from St. Louis to the Cayman Islands, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from St. Louis to Cayman Islands?

How long is the flight from St. Louis to Cayman Islands?

Can I find deals for flights from St. Louis to Cayman Islands that include hotel bookings?

How can I find direct flights from St. Louis to Cayman Islands?

Can I find deals for business class flights from St. Louis to Cayman Islands?

What is the cheapest month to book a flight from St. Louis to Cayman Islands?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from St. Louis to Cayman Islands

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Cheapest flights from St. Louis to Cayman Islands
Explore the most affordable flight options available from St. Louis to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.