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Cayman Islands

$356+ Cheap flights from Louisville (SDF) to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — GCM
Jan 21 — Jan 281
Wed 1/21
Wed 1/28
1 adult, Economy
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Cheap flight deals from Louisville to Cayman Islands

Cheapest flights from Louisville to Cayman Islands
Explore the most affordable flight options available from Louisville to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 22, 2025.

This Delta deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:30 amSDF - GCM
1 stop5h 57mDelta
Tue 12/301:52 pmGCM - SDF
1 stop6h 59mDelta
Deal found 12/20$714
This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:40 amSDF - GCM
2 stops10h 55mUnited Airlines
Tue 12/305:10 pmGCM - SDF
2 stops20h 03mUnited Airlines
Deal found 12/20$719
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:00 amSDF - GCM
1 stop8h 27mDelta
Mon 1/53:45 pmGCM - SDF
1 stop8h 10mDelta
Deal found 12/21$758
This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:24 pmSDF - GCM
1 stop16h 33mAmerican Airlines
Mon 1/53:35 pmGCM - SDF
1 stop7h 55mAmerican Airlines
Deal found 12/20$764

Find flight deals from Louisville to Cayman Islands

Keep the following information in mind while searching for Louisville to Cayman Islands flight deals. Data was last updated December 22, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$356
(Kiwi.com)

Popular in

October

Cheapest in

September

Average price

$676
Provider with most accurate pricing for Louisville Intl-George Town Owen Roberts Intl flight deals.
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Provider most trusted by Cheapflights users for Louisville Intl-George Town Owen Roberts Intl flights.
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From Louisville Intl to Cayman Islands
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High demand for flights, 3% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2025.
Use the filters below to find and compare flights from Louisville to the Cayman Islands that are best for you.

Fly from

Louisville

Fly to

Cayman Islands

Route

Depart

Return

Price

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Wed 1/21

1:55 pm-1:53 pm

2 stops23h 58m

George Town Owen Roberts Intl

Thu 2/5

2:49 pm-6:04 pm

1 stop27h 15m

$383

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Fri 1/23

7:51 pm-10:57 am

1 stop15h 06m

George Town Owen Roberts Intl

Wed 2/4

2:05 pm-7:39 pm

1 stop5h 34m

$406

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Mon 1/19

6:00 am-11:26 am

1 stop5h 26m

George Town Owen Roberts Intl

Sat 1/24

3:45 pm-11:59 pm

1 stop8h 14m

$406

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Sat 1/17

6:00 am-11:00 am

1 stop5h 00m

George Town Owen Roberts Intl

Mon 2/2

2:05 pm-8:56 pm

1 stop6h 51m

$406

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Fri 1/23

7:51 pm-10:57 am

1 stop15h 06m

George Town Owen Roberts Intl

Tue 2/3

2:05 pm-7:39 pm

1 stop5h 34m

$406

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Fri 2/6

7:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Sun 2/8

2:05 pm-11:50 pm

1 stop9h 45m

$406

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Sat 1/17

6:23 am-2:40 pm

1 stop8h 17m

George Town Owen Roberts Intl

Tue 2/3

2:05 pm-7:39 pm

1 stop5h 34m

$406

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Fri 1/23

6:23 am-2:40 pm

1 stop8h 17m

George Town Owen Roberts Intl

Sat 1/31

2:05 pm-11:50 pm

1 stop9h 45m

$406

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Thu 1/22

5:35 am-12:40 pm

1 stop7h 05m

George Town Owen Roberts Intl

Fri 2/6

2:05 pm-11:50 pm

1 stop9h 45m

$406

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Sun 1/18

7:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Fri 2/6

2:05 pm-11:50 pm

1 stop9h 45m

$406

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/19

Showing 1-10 of 12 results
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Best time to book a flight from Louisville to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to the Cayman Islands

What is the cheapest month to book a flight from Louisville to Cayman Islands?

Currently, April is the cheapest month in which you can book a flight from Louisville to Cayman Islands (average of $267). Flying from Louisville to Cayman Islands in December is currently the most expensive (average of $545). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated December 22, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Louisville to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,014 reviews

Boarding

8.1

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,014 reviews
Delta
7.9
Good
8,014 reviews

Boarding

8.1

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,052 reviews
Delta
7.9
Good
8,014 reviews

Boarding

8.1

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to Cayman Islands?

    Most people fly from Louisville Intl (SDF) if they book a flight from Louisville to Cayman Islands. Louisville Intl is conveniently located just 5.3 mi from Louisville’s city center.

  • How long is the flight from Louisville to Cayman Islands?

    Airlines like Delta fly from Louisville to Cayman Islands in about 15h 06m. The time it takes to get you to your destination can typically vary by up to . The distance from Louisville to Cayman Islands is about 1330 mi.

  • Can I find deals for flights from Louisville to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Louisville to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Cayman Islands.

  • Can I find deals for business class flights from Louisville to Cayman Islands?

    Yes. Cheapflights offers flight deals from Louisville to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Cayman Islands?

    Currently, April is the cheapest month in which you can book a flight from Louisville to Cayman Islands (average of $267). Flying from Louisville to Cayman Islands in December is currently the most expensive (average of $545). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Louisville to Cayman Islands

Discover the top 2 airlines that operate flights from Louisville to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$418Average$591FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$448Average$658FlexibilityNo cancel feeOn-time71%

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