HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cayman Islands

$484+ Cheap flights from Louisville (SDF) to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — GCM
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Louisville to Cayman Islands with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Louisville to Cayman Islands

Cheapest flights from Louisville to Cayman Islands
Explore the most affordable flight options available from Louisville to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:30 amSDF - GCM
1 stop5h 57mDelta
Wed 12/313:42 pmGCM - SDF
1 stop8h 14mDelta
Deal found 11/3$484
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/187:05 amSDF - GCM
1 stop5h 30mDelta
Wed 12/31:50 pmGCM - SDF
1 stop10h 09mDelta
Deal found 11/2$554
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:00 amSDF - GCM
1 stop6h 36mDelta
Wed 12/311:52 pmGCM - SDF
1 stop10h 04mDelta
Deal found 11/3$557
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:00 amSDF - GCM
1 stop6h 45mUnited Airlines
Mon 12/15:45 pmGCM - SDF
2 stops17h 47mUnited Airlines
Deal found 11/2$559
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:07 pmSDF - GCM
1 stop19h 38mUnited Airlines
Mon 12/15:45 pmGCM - SDF
2 stops17h 47mUnited Airlines
Deal found 11/2$566
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:07 pmSDF - GCM
2 stops22h 23mUnited Airlines
Mon 12/15:45 pmGCM - SDF
2 stops26h 43mUnited Airlines
Deal found 11/2$599
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2810:50 amSDF - GCM
1 stop26h 55mUnited Airlines
Wed 12/312:50 pmGCM - SDF
1 stop7h 40mUnited Airlines
Deal found 11/3$602
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:05 amSDF - GCM
1 stop8h 40mSpirit Airlines
Thu 1/12:40 pmGCM - SDF
1 stop9h 19mSpirit Airlines
Deal found 11/3$605
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:10 amSDF - GCM
1 stop9h 20mUnited Airlines
Wed 12/35:45 pmGCM - SDF
1 stop28h 12mUnited Airlines
Deal found 11/2$606
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:24 pmSDF - GCM
1 stop16h 33mAmerican Airlines
Mon 1/53:45 pmGCM - SDF
1 stop8h 14mAmerican Airlines
Deal found 11/3$609

Cheap flight deals from Louisville to Cayman Islands

Keep the following information in mind while searching for Louisville to Cayman Islands flight deals. Data was last updated November 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$484
(American Airlines)

Popular in

October

Cheapest in

September

Average price

$479
Provider with most accurate pricing for Louisville Intl-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-George Town Owen Roberts Intl flights.
Search Deals
From Louisville Intl to Cayman Islands
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Louisville to the Cayman Islands that are best for you.

Fly from

Louisville

Fly to

Cayman Islands

Route

Depart

Return

Price

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Sat 1/10

7:11 pm-11:26 am

1 stop16h 15m

George Town Owen Roberts Intl

Fri 1/16

12:16 pm-10:12 pm

1 stop9h 56m

$484

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Tue 12/30

8:30 am-2:27 pm

1 stop5h 57m

George Town Owen Roberts Intl

Wed 12/31

3:42 pm-11:56 pm

1 stop8h 14m

$484

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Mon 1/19

5:35 am-12:40 pm

1 stop7h 05m

George Town Owen Roberts Intl

Sat 1/24

3:25 pm-11:50 pm

1 stop8h 25m

$509

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Mon 1/19

6:32 pm-12:05 pm

2 stops17h 33m

George Town Owen Roberts Intl

Sat 1/24

3:51 pm-11:19 pm

1 stop7h 28m

$514

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Tue 11/18

7:05 am-12:35 pm

1 stop5h 30m

George Town Owen Roberts Intl

Wed 12/3

1:50 pm-11:59 pm

1 stop10h 09m

$554

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Wed 11/19

7:05 am-12:35 pm

1 stop5h 30m

George Town Owen Roberts Intl

Thu 11/27

1:50 pm-11:00 pm

1 stop9h 10m

$554

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Wed 11/19

6:00 am-12:35 pm

1 stop6h 35m

George Town Owen Roberts Intl

Wed 12/3

1:50 pm-11:59 pm

1 stop10h 09m

$554

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Tue 11/18

6:00 am-12:35 pm

1 stop6h 35m

George Town Owen Roberts Intl

Thu 11/27

1:50 pm-11:00 pm

1 stop9h 10m

$554

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Mon 12/29

6:00 am-12:36 pm

1 stop6h 36m

George Town Owen Roberts Intl

Wed 12/31

1:52 pm-11:56 pm

1 stop10h 04m

$557

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Sat 11/22

7:00 am-1:45 pm

1 stop6h 45m

George Town Owen Roberts Intl

Mon 12/1

5:45 pm-11:32 am

2 stops17h 47m

$559

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Best time to book a flight from Louisville to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to the Cayman Islands

What is the cheapest month to book a flight from Louisville to Cayman Islands?

Currently, April is the cheapest month in which you can book a flight from Louisville to Cayman Islands (average of $327). Flying from Louisville to Cayman Islands in December is currently the most expensive (average of $532). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated November 4, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Louisville to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Crew

8.5

Overall

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Crew

8.5

Overall

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
8,997 reviews
Delta
7.9
Good
8,002 reviews

Crew

8.5

Overall

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,038 reviews
Delta
7.9
Good
8,002 reviews

Crew

8.5

Overall

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to Cayman Islands?

    Most people fly from Louisville Intl (SDF) if they book a flight from Louisville to Cayman Islands. Louisville Intl is conveniently located just 5.3 mi from Louisville’s city center.

  • How long is the flight from Louisville to Cayman Islands?

    Airlines like American Airlines and Delta fly from Louisville to Cayman Islands in about 5h 57m. The time it takes to get you to your destination can typically vary by up to 10h 18m. The distance from Louisville to Cayman Islands is about 1330 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Louisville to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Louisville to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Cayman Islands.

  • Can I find deals for business class flights from Louisville to Cayman Islands?

    Yes. Cheapflights offers flight deals from Louisville to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Cayman Islands?

    Currently, April is the cheapest month in which you can book a flight from Louisville to Cayman Islands (average of $327). Flying from Louisville to Cayman Islands in December is currently the most expensive (average of $532). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Louisville to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
Cincinnati to Luis Munoz Marin Intl flights
Cincinnati to Saint Thomas Island flights
Nashville to Luis Munoz Marin Intl flights
Louisville to Luis Munoz Marin Intl flights
Cincinnati to Punta Cana flights
Nashville to Punta Cana flights
Nashville to Oranjestad flights
Cincinnati to Oranjestad flights
Nashville to Saint Thomas Island flights
Cincinnati to Nassau flights
Nashville to Nassau flights
Knoxville to Luis Munoz Marin Intl flights
Nashville to Providenciales flights
Cincinnati to Montego Bay flights
Lexington to Luis Munoz Marin Intl flights
Cincinnati to Willemstad flights
Louisville to Punta Cana flights
Cincinnati to Santiago de los Caballeros flights
Louisville to Providenciales flights
Cincinnati to Puerto Plata flights
Cincinnati to Simpson Bay flights
Knoxville to Oranjestad flights
Nashville to Willemstad flights
Lexington to Nassau flights
Knoxville to Montego Bay flights
Cincinnati to Santo Domingo flights
Lexington to Simpson Bay flights
Louisville to Saint Thomas Island flights
Lexington to Punta Cana flights
Nashville to Montego Bay flights
Lexington to Montego Bay flights
Nashville to Santo Domingo flights
Nashville to Castries flights
Cincinnati to George Town flights
Cincinnati to Providenciales flights
Blountville to Montego Bay flights
Blountville to Luis Munoz Marin Intl flights
Nashville to Road Town flights
Knoxville to Castries flights
Cincinnati to Road Town flights
Nashville to Gregory Town flights
Nashville to George Town flights
Cincinnati to St. John's flights
Cincinnati to Christiansted flights
Lexington to Santo Domingo flights
Knoxville to Providenciales flights
Cincinnati to Castries flights
Lexington to Saint Thomas Island flights
Knoxville to Saint Thomas Island flights
Louisville to George Town flights

Top 3 airlines flying from Louisville to Cayman Islands

Discover the top 3 airlines that operate flights from Louisville to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$418Average$483FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$439Average$568FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$475Average$619FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.