HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cayman Islands

$499+ Cheap flights from Greenville (GSP) to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — GCM
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greenville to Cayman Islands with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Greenville to Cayman Islands

Keep the following information in mind while searching for Greenville to Cayman Islands flight deals. Data was last updated April 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$499
(American Airlines)

Popular in

February

Cheapest in

December

Average price

$488
Provider with most accurate pricing for Greenville-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-George Town Owen Roberts Intl flights.
Search Deals
From Greenville to Cayman Islands
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($86 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Greenville to Cayman Islands

Cheapest flights from Greenville to Cayman Islands
Explore the most affordable flight options available from Greenville to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/97:16 pmGSP - GCM
2 stops16h 54mAmerican Airlines
Sat 8/1612:10 pmGCM - GSP
2 stops10h 47mAmerican Airlines
Deal found 4/29$499
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/227:35 amGSP - GCM
1 stop4h 45mDelta
Thu 5/2912:35 pmGCM - GSP
1 stop6h 40mDelta
Deal found 4/30$532

Cheapflights Fare Finder

Customize your flight search to find flights from Greenville to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Greenville to the Cayman Islands that are best for you.

Fly from

Greenville

Fly to

Cayman Islands

Route

Depart

Return

Price

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Sat 8/9

7:16 pm-11:10 am

2 stops16h 54m

George Town Owen Roberts Intl

Sat 8/16

12:10 pm-11:57 pm

2 stops10h 47m

$499

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Thu 5/22

7:35 am-11:20 am

1 stop4h 45m

George Town Owen Roberts Intl

Thu 5/29

12:35 pm-8:15 pm

1 stop6h 40m

$532

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Best time to book a flight from Greenville to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to the Cayman Islands

What is the cheapest month to book a flight from Greenville to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from Greenville to Cayman Islands (average of $467). Flying from Greenville to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated April 30, 2025.
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Cayman Islands?

    Located just 10.4 mi from the city center, Greenville (GSP) is the airport most travelers will use when flying to Cayman Islands from Greenville.

  • Can I find deals for flights from Greenville to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Greenville to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Cayman Islands.

  • Can I find deals for business class flights from Greenville to Cayman Islands?

    Yes. Cheapflights offers flight deals from Greenville to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Greenville to Cayman Islands (average of $467). Flying from Greenville to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Greenville to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Luis Munoz Marin Intl flights
Charlotte to Punta Cana flights
Charlotte to Montego Bay flights
Charlotte to Oranjestad flights
Charlotte to Saint Thomas Island flights
Charleston to Luis Munoz Marin Intl flights
Charlotte to Nassau flights
Charlotte to Simpson Bay flights
Charlotte to Castries flights
Charlotte to Providenciales flights
Charlotte to Bridgetown flights
Charleston to Montego Bay flights
Greenville to Luis Munoz Marin Intl flights
Charlotte to Santo Domingo flights
Savannah to Luis Munoz Marin Intl flights
Charlotte to Willemstad flights
Greenville to Montego Bay flights
Charlotte to Santiago de los Caballeros flights
Charleston to Saint Thomas Island flights
Charleston to Punta Cana flights
Charlotte to Marsh Harbour flights
Savannah to Montego Bay flights
Charlotte to George Town flights
Charlotte to Puerto Plata flights
Greenville to Nassau flights
Charlotte to Christiansted flights
Charleston to Nassau flights
Charleston to Oranjestad flights
Charlotte to St. George's flights
Charleston to Providenciales flights
Myrtle Beach to Oranjestad flights
Myrtle Beach to Montego Bay flights
Myrtle Beach to Luis Munoz Marin Intl flights
Augusta to Saint Thomas Island flights
Columbia to Saint Thomas Island flights
Charlotte to St. John's flights
Charleston to Bridgetown flights
Savannah to Nassau flights
Columbia to Luis Munoz Marin Intl flights
Greenville to Punta Cana flights
Charleston to Santo Domingo flights
Charlotte to Georgetown flights
Greenville to Oranjestad flights
Greenville to Saint Thomas Island flights
Savannah to Providenciales flights
Columbia to Montego Bay flights
Myrtle Beach to Nassau flights
Myrtle Beach to Punta Cana flights
Savannah to Oranjestad flights
Columbia to Oranjestad flights

Top airline flying from Greenville to Cayman Islands

Discover the top airline that operate flights from Greenville to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$446Average$580FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.