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Cayman Islands

$257+ Cheap flights from Des Moines (DSM) to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GCM
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Des Moines to Cayman Islands

Keep the following information in mind while searching for Des Moines to Cayman Islands flight deals. Data was last updated junio 12, 2025.

Round-trip from

$576
(American Airlines)

One-way from

$257
(Southwest)

Popular in

December

Cheapest in

August

Average price

$667
From Des Moines to Cayman Islands
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One-way flight from Des Moines to Cayman Islands
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Highest demand for flights based on searches. 13% potential increase in price ($108 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($44 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Des Moines to Cayman Islands

Cheapest flights from Des Moines to Cayman Islands
Explore the most affordable flight options available from Des Moines to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/146:11 pmDSM - GCM
1 stop17h 14mAmerican Airlines
mié. 9/1712:25 pmGCM - DSM
1 stop10h 42mAmerican Airlines
Deal found 6/10$576
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/47:30 amDSM - GCM
1 stop9h 50mMultiple Airlines
dom. 8/1012:40 pmGCM - DSM
1 stop25h 12mMultiple Airlines
Deal found 6/11$595
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/15:30 amDSM - GCM
1 stop5h 52mDelta
lun. 8/1112:52 pmGCM - DSM
1 stop9h 47mDelta
Deal found 6/11$660
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/46:02 amDSM - GCM
1 stop6h 28mUnited Airlines
mié. 8/131:35 pmGCM - DSM
1 stop8h 42mUnited Airlines
Deal found 6/11$700
This WestJet deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WestJet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/75:52 pmDSM - GCM
2 stops42h 53mWestJet
mar. 8/121:45 pmGCM - DSM
2 stops30h 45mWestJet
Deal found 6/11$3,791

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Des Moines to the Cayman Islands that are best for you.

Fly from

Des Moines

Fly to

Cayman Islands

Route

Depart

Return

Price

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

dom. 9/14

6:11 pm-11:25 am

1 stop17h 14m

George Town Owen Roberts Intl

mié. 9/17

12:25 pm-11:07 pm

1 stop10h 42m

$576

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

lun. 8/4

7:30 am-5:20 pm

1 stop9h 50m

George Town Owen Roberts Intl

dom. 8/10

12:40 pm-1:52 pm

1 stop25h 12m

$595

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

vie. 8/1

5:30 am-11:22 am

1 stop5h 52m

George Town Owen Roberts Intl

lun. 8/11

12:52 pm-10:39 pm

1 stop9h 47m

$660

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

lun. 8/4

6:02 am-12:30 pm

1 stop6h 28m

George Town Owen Roberts Intl

mié. 8/13

1:35 pm-10:17 pm

1 stop8h 42m

$700

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

jue. 8/7

5:52 pm-12:45 pm

2 stops42h 53m

George Town Owen Roberts Intl

mar. 8/12

1:45 pm-8:30 pm

2 stops30h 45m

$3,791

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

vie. 7/11

1:35 pm-10:35 am

2 stops21h 00m

$257

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

vie. 7/25

2:00 pm-12:45 pm

2 stops22h 45m

$301

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

vie. 7/11

5:30 am-11:22 am

1 stop5h 52m

$318

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

vie. 7/25

5:17 pm-9:50 am

1 stop16h 33m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from Des Moines to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to the Cayman Islands

What is the cheapest time of day to fly from DSM to KY?

Find hourly flight availability from Des Moines to Cayman Islands. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Cayman Islands as you normally would.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated junio 12, 2025.
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Crew

8.6

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Crew

8.6

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,950 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Crew

8.6

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Crew

8.6

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Crew

8.6

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
WestJet
7.2
Good
2,868 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Crew

8.6

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Cayman Islands?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Cayman Islands. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to Cayman Islands one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $257. Delta flights start at $318 while deals on American Airlines start at $319 one-way.

  • Can I find deals for flights from Des Moines to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Des Moines to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Cayman Islands.

  • Can I find deals for business class flights from Des Moines to Cayman Islands?

    Yes. Cheapflights offers flight deals from Des Moines to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Cayman Islands (average of $467). Flying from Des Moines to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Des Moines to Culebra flights
Omaha to Kingstown flights

Top 2 airlines flying from Des Moines to Cayman Islands

Discover the top 2 airlines that operate flights from Des Moines to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$457Average$605FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$542Average$635FlexibilityNo cancel feeOn-time71%

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