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Cape Cod and the Islands

$279+ Cheap flights from South Carolina to Cape Cod and the Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ACK
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from South Carolina to Cape Cod and the Islands

Keep the following information in mind while searching for South Carolina to Cape Cod and the Islands flight deals. Data was last updated September 16, 2025.

Round-trip from

$430
(JetBlue)

One-way from

$279
(Kiwi.com)

Popular in

November

Cheapest in

February

Average price

$175
From South Carolina to Cape Cod and the Islands
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One-way flight from South Carolina to Cape Cod and the Islands
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Highest demand for flights based on searches. 12% potential increase in price ($21 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from South Carolina to Cape Cod and the Islands

Cheapest flights from South Carolina to Cape Cod and the Islands
Explore the most affordable flight options available from South Carolina to Cape Cod and the Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:00 amCHS - ACK
1 stop6h 21mJetBlue
Mon 10/135:27 pmACK - CHS
2 stops15h 27mJetBlue
Deal found 9/15$509
This United deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:00 amCHS - PVC
2 stops14h 18mMultiple Airlines
Tue 10/216:45 amPVC - CHS
2 stops9h 55mMultiple Airlines
Deal found 9/14$510
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:36 pmCLT - HYA
2 stops19h 09mMultiple Airlines
Sun 10/510:29 amHYA - CLT
1 stop5h 34mMultiple Airlines
Deal found 9/13$532
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3010:46 amCLT - HYA
2 stops25h 20mMultiple Airlines
Sat 10/41:15 pmHYA - CLT
1 stop26h 48mMultiple Airlines
Deal found 9/15$601
This United deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:00 amCLT - HYA
2 stops11h 39mMultiple Airlines
Sun 12/712:07 pmHYA - CLT
2 stops21h 55mMultiple Airlines
Deal found 9/13$629
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/259:29 amCHS - MVY
1 stop6h 21mJetBlue
Mon 12/111:40 amMVY - CHS
1 stop7h 45mJetBlue
Deal found 9/15$634
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1411:10 amCHS - PVC
2 stops9h 08mJetBlue
Tue 10/216:45 amPVC - CHS
1 stop5h 20mJetBlue
Deal found 9/14$639
This United deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:00 amCHS - MVY
2 stops9h 50mMultiple Airlines
Mon 12/15:00 pmMVY - CHS
2 stops22h 10mMultiple Airlines
Deal found 9/15$695
This JetBlue deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:43 amCHS - MVY
1 stop5h 07mJetBlue
Mon 11/101:34 pmMVY - CHS
1 stop6h 08mJetBlue
Deal found 9/15$729
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:34 pmCLT - MVY
1 stop16h 31mMultiple Airlines
Sun 9/285:39 pmMVY - CLT
2 stops27h 58mMultiple Airlines
Deal found 9/14$736
This JetBlue deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:00 amCHS - PVC
1 stop6h 48mJetBlue
Mon 10/136:45 amPVC - CHS
1 stop5h 20mJetBlue
Deal found 9/14$745
This JetBlue deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/298:00 amCHS - ACK
1 stop5h 21mJetBlue
Fri 10/38:26 amACK - CHS
1 stop7h 50mJetBlue
Deal found 9/14$769

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cape Cod and the Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from South Carolina to Cape Cod and the Islands that are best for you.

Fly from

South Carolina

Fly to

Cape Cod and the Islands

Route

Depart

Return

Price

CharlestonNantucket

CHS - ACK

CHSACK

Charleston

Sat 10/11

7:00 am-1:21 pm

1 stop6h 21m

Nantucket Memorial

Mon 10/13

5:27 pm-8:54 am

2 stops15h 27m

$509

CharlestonProvincetown

CHS - PVC

CHSPVC

Charleston

Tue 10/14

6:00 am-8:18 pm

2 stops14h 18m

Provincetown

Tue 10/21

6:45 am-4:40 pm

2 stops9h 55m

$510

CharlotteHyannis

CLT - HYA

CLTHYA

Charlotte Douglas

Fri 10/3

5:36 pm-12:45 pm

2 stops19h 09m

Hyannis Barnstable

Sun 10/5

10:29 am-4:03 pm

1 stop5h 34m

$532

CharlotteHyannis

CLT - HYA

CLTHYA

Charlotte Douglas

Tue 9/30

10:46 am-12:06 pm

2 stops25h 20m

Hyannis Barnstable

Sat 10/4

1:15 pm-4:03 pm

1 stop26h 48m

$601

CharlotteHyannis

CLT - HYA

CLTHYA

Charlotte Douglas

Fri 12/5

7:00 am-6:39 pm

2 stops11h 39m

Hyannis Barnstable

Sun 12/7

12:07 pm-10:02 am

2 stops21h 55m

$629

CharlestonWest Tisbury

CHS - MVY

CHSMVY

Charleston

Tue 11/25

9:29 am-3:50 pm

1 stop6h 21m

West Tisbury Martha's Vineyard

Mon 12/1

11:40 am-7:25 pm

1 stop7h 45m

$634

CharlestonProvincetown

CHS - PVC

CHSPVC

Charleston

Tue 10/14

11:10 am-8:18 pm

2 stops9h 08m

Provincetown

Tue 10/21

6:45 am-12:05 pm

1 stop5h 20m

$639

CharlestonWest Tisbury

CHS - MVY

CHSMVY

Charleston

Tue 11/25

6:00 am-3:50 pm

2 stops9h 50m

West Tisbury Martha's Vineyard

Mon 12/1

5:00 pm-3:10 pm

2 stops22h 10m

$695

CharlestonWest Tisbury

CHS - MVY

CHSMVY

Charleston

Fri 11/7

10:43 am-3:50 pm

1 stop5h 07m

West Tisbury Martha's Vineyard

Mon 11/10

1:34 pm-7:42 pm

1 stop6h 08m

$729

CharlotteWest Tisbury

CLT - MVY

CLTMVY

Charlotte Douglas

Fri 9/26

3:34 pm-8:05 am

1 stop16h 31m

West Tisbury Martha's Vineyard

Sun 9/28

5:39 pm-9:37 pm

2 stops27h 58m

$736

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 34 results
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Best time to book a flight from South Carolina to Cape Cod and the Islands

Have a flexible travel schedule? Discover the best time to fly to Cape Cod and the Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Cape Cod and the Islands
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cape Cod and the Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Cape Cod and the Islands?

    For as low as $509, JetBlue can have you in Cape Cod and the Islands from South Carolina in 6h 21m. Airlines will cover a distance of 796 mi.

  • Can I find deals for flights from South Carolina to Cape Cod and the Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cape Cod and the Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cape Cod and the Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cape Cod and the Islands.

  • Can I find deals for business class flights from South Carolina to Cape Cod and the Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cape Cod and the Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for South Carolina to Cape Cod and the Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Cape Cod and the Islands

Discover the top 2 airlines that operate flights from South Carolina to Cape Cod and the Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$190Average$435FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$211Average$338FlexibilityNo cancel feeOn-time71%

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