Cape Cod and the Islands

$233+ Cheap flights from South Carolina to Cape Cod and the Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MVY
Mar 6 — Mar 131
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Cheap flight deals from South Carolina to Cape Cod and the Islands

Cheapest flights from South Carolina to Cape Cod and the Islands
Explore the most affordable flight options available from South Carolina to Cape Cod and the Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This JetBlue deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:00 am
CHS
-
MVY
1 stop5h 01m
JetBlue
Tue 8/1111:25 am
MVY
-
CHS
1 stop7h 40m
JetBlue
Deal found 2/3$233
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:00 am
CHS
-
MVY
2 stops11h 25m
American Airlines
Tue 8/112:07 pm
MVY
-
CHS
1 stop6h 57m
American Airlines
Deal found 2/2$277
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/159:27 am
CLT
-
ACK
1 stop7h 07m
American Airlines
Sat 8/2212:50 pm
ACK
-
CLT
Nonstop2h 20m
American Airlines
Deal found 2/3$283
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:00 am
CHS
-
ACK
1 stop4h 23m
JetBlue
Sat 8/293:38 pm
ACK
-
CHS
1 stop4h 42m
JetBlue
Deal found 2/2$295
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:20 am
SAV
-
MVY
1 stop4h 41m
JetBlue
Tue 9/111:25 am
MVY
-
SAV
1 stop7h 36m
JetBlue
Deal found 2/2$358
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/111:00 am
CHS
-
MVY
1 stop5h 01m
JetBlue
Wed 8/511:25 am
MVY
-
CHS
1 stop7h 40m
JetBlue
Deal found 2/2$364
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:05 am
CHS
-
ACK
2 stops11h 23m
American Airlines
Sun 8/25:42 pm
ACK
-
CHS
1 stop4h 59m
American Airlines
Deal found 2/2$384
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:28 am
CLT
-
ACK
1 stop5h 06m
American Airlines
Sat 8/12:19 pm
ACK
-
CLT
1 stop6h 28m
American Airlines
Deal found 2/2$409
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:51 am
GSP
-
MVY
1 stop4h 05m
American Airlines
Mon 6/2912:26 pm
MVY
-
GSP
1 stop5h 56m
American Airlines
Deal found 2/2$422
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/159:20 am
CLT
-
ACK
1 stop7h 08m
American Airlines
Sun 7/192:19 pm
ACK
-
CLT
1 stop6h 28m
American Airlines
Deal found 2/2$424
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/19:20 am
CLT
-
ACK
1 stop4h 29m
American Airlines
Sat 8/810:29 am
ACK
-
CLT
1 stop10h 51m
American Airlines
Deal found 2/2$431
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:54 am
CLT
-
MVY
1 stop11h 11m
American Airlines
Sun 7/127:35 pm
MVY
-
CLT
1 stop10h 50m
American Airlines
Deal found 2/3$443

Find flight deals from South Carolina to Cape Cod and the Islands

Keep the following information in mind while searching for South Carolina to Cape Cod and the Islands flight deals. Data was last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$364
(JetBlue)

One-way from

$243
(Delta)

Popular in

December

Cheapest in

February

Average price

$96
Provider with most accurate pricing for Myrtle Beach Intl-Boston Logan Intl flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Boston Logan Intl flights.
From South Carolina to Cape Cod and the Islands
One-way flight from South Carolina to Cape Cod and the Islands
Highest demand for flights based on searches. 39% potential increase in price ($128 potential increase over avg. RT price).
Cheapest flight prices on average. 10% potential price decrease ($19 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cape Cod and the Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from South Carolina to Cape Cod and the Islands that are best for you.

Fly from

South Carolina

Fly to

Cape Cod and the Islands

Route

Depart

Return

Price

CharlestonWest Tisbury

CHS - MVY

CHSMVY

Charleston

Sat 8/1

11:00 am-4:01 pm

1 stop5h 01m

West Tisbury Martha's Vineyard

Wed 8/5

11:25 am-7:05 pm

1 stop7h 40m

$364

CharlestonNantucket

CHS - ACK

CHSACK

Charleston

Thu 7/30

5:05 am-4:28 pm

2 stops11h 23m

Nantucket Memorial

Sun 8/2

5:42 pm-10:41 pm

1 stop4h 59m

$384

CharlotteNantucket

CLT - ACK

CLTACK

Charlotte Douglas

Sat 7/25

9:28 am-2:34 pm

1 stop5h 06m

Nantucket Memorial

Sat 8/1

2:19 pm-8:47 pm

1 stop6h 28m

$409

GreenvilleWest Tisbury

GSP - MVY

GSPMVY

Greenville

Thu 6/25

7:51 am-11:56 am

1 stop4h 05m

West Tisbury Martha's Vineyard

Mon 6/29

12:26 pm-6:22 pm

1 stop5h 56m

$422

CharlotteWest Tisbury

CLT - MVY

CLTMVY

Charlotte Douglas

Wed 7/8

7:54 am-7:05 pm

1 stop11h 11m

West Tisbury Martha's Vineyard

Sun 7/12

7:35 pm-6:25 am

1 stop10h 50m

$443

CharlotteNantucket

CLT - ACK

CLTACK

Charlotte Douglas

Sat 8/1

9:53 am-12:19 pm

Nonstop2h 26m

Nantucket Memorial

Sat 8/8

10:29 am-7:06 pm

1 stop8h 37m

$459

CharlotteNantucket

CLT - ACK

CLTACK

Charlotte Douglas

Sat 5/30

7:00 am-11:27 am

1 stop4h 27m

Nantucket Memorial

Fri 6/5

3:57 pm-11:53 pm

2 stops7h 56m

$474

CharlotteNantucket

CLT - ACK

CLTACK

Charlotte Douglas

Wed 6/24

9:20 am-1:49 pm

1 stop4h 29m

Nantucket Memorial

Mon 6/29

10:24 am-5:00 pm

1 stop6h 36m

$503

SavannahHyannis

SAV - HYA

SAVHYA

Savannah/Hilton Head

Fri 2/27

12:39 pm-5:20 pm

1 stop4h 41m

Hyannis Barnstable

Mon 3/2

7:05 am-11:49 am

1 stop4h 44m

$565

SavannahWest Tisbury

SAV - MVY

SAVMVY

Savannah/Hilton Head

Fri 2/27

12:39 pm-6:50 pm

1 stop6h 11m

West Tisbury Martha's Vineyard

Mon 3/2

7:09 am-11:49 am

1 stop4h 40m

$684

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 42 results
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Best time to book a flight from South Carolina to Cape Cod and the Islands

Have a flexible travel schedule? Discover the best time to fly to Cape Cod and the Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Cape Cod and the Islands
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cape Cod and the Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from South Carolina to Cape Cod and the Islands?

    For as low as $474, JetBlue can have you in Cape Cod and the Islands from South Carolina in 4h 27m. Airlines will cover a distance of 722 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from South Carolina to Cape Cod and the Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cape Cod and the Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cape Cod and the Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cape Cod and the Islands.

  • Can I find deals for business class flights from South Carolina to Cape Cod and the Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cape Cod and the Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Cape Cod and the Islands

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to Cape Cod and the Islands

Discover the top 2 airlines that operate flights from South Carolina to Cape Cod and the Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$157Average$430FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$211Average$342FlexibilityNo cancel feeOn-time71%

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