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$132+ Cheap flights from Santo Domingo (SDQ) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CLO
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl are usually found in August or September, booked 51 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Santo Domingo to Cali

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Cali (CLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$351
(Copa Airlines)

One-way from

$132
(Mytrip)

Popular in

October

Cheapest in

August

Average price

$350
From Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
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One-way flight from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
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Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Santo Domingo to Cali

Cheapest flights from Santo Domingo to Cali
Explore the most affordable flight options available from Santo Domingo to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/208:55 amSDQ - CLO
1 stop9h 30mCopa Airlines
Sun 8/314:41 amCLO - SDQ
1 stop7h 29mCopa Airlines
Deal found 6/10$351
This Avianca deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:15 pmSDQ - CLO
1 stop14h 06mAvianca
Sun 11/99:10 amCLO - SDQ
1 stop7h 10mAvianca
Deal found 6/11$354
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/16:10 pmSDQ - CLO
1 stop5h 42mMultiple Airlines
Tue 8/129:05 amCLO - SDQ
2 stops10h 10mMultiple Airlines
Deal found 6/10$411
This FlightHub deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/242:45 amSDQ - CLO
1 stop11h 40mSpirit Airlines
Mon 9/82:20 pmCLO - SDQ
1 stop10h 21mSpirit Airlines
Deal found 6/10$497
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/710:15 amSDQ - CLO
1 stop11h 30mAmerican Airlines
Thu 7/1012:30 amCLO - SDQ
1 stop7h 45mAmerican Airlines
Deal found 6/11$1,537

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Santo Domingo to Cali that are best for you.

Fly from

Santo Domingo

Fly to

Cali

Route

Depart

Return

Price

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Thu 7/3

5:23 am-2:22 pm

1 stop9h 59m

Cali Alfonso B. Aragon Intl

Sun 8/3

4:41 am-10:59 am

1 stop5h 18m

$351

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Fri 11/7

6:15 pm-11:06 pm

1 stop5h 51m

Cali Alfonso B. Aragon Intl

Sun 11/9

9:54 am-5:20 pm

1 stop6h 26m

$354

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Tue 7/1

6:10 pm-10:52 pm

1 stop5h 42m

Cali Alfonso B. Aragon Intl

Tue 8/12

9:05 am-8:15 pm

2 stops10h 10m

$411

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Sun 8/24

2:45 am-1:25 pm

1 stop11h 40m

Cali Alfonso B. Aragon Intl

Mon 9/8

2:20 pm-1:41 am

1 stop10h 21m

$497

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Mon 7/7

10:15 am-8:45 pm

1 stop11h 30m

Cali Alfonso B. Aragon Intl

Thu 7/10

12:30 am-9:15 am

1 stop7h 45m

$1,537

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Sat 8/30

7:40 am-8:38 pm

1 stop13h 58m

$132

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Thu 7/17

5:23 am-2:22 pm

1 stop9h 59m

$166

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Mon 11/10

11:50 am-6:04 pm

1 stop7h 14m

$170

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Thu 8/28

2:45 am-1:25 pm

1 stop11h 40m

$350

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Santo Domingo to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Cali

How far ahead should I book a flight from Santo Domingo to Cali?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Cali. Price data was last updated on June 9, 2025.

To ensure you get the cheapest price possible for a flight from Santo Domingo to Cali, you should look to book at least 51 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santo Domingo to Cali?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $351). Flying from Santo Domingo to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Cali by month

Plan your trip to Cali by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Cali ranges from 1.2 - 5.5 inches per month. April is typically the wettest month, when rainfall can reach 5.5 in. July is typically the driest time to visit Cali when rainfall is around 1.2 in.

Temperature in Cali by month

Plan your trip to Cali by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Cali, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated June 12, 2025.
Read through reviews of airlines operating flights from Santo Domingo to Cali, such as Copa Airlines, American Airlines and Avianca. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,451 reviews

Food

6.8

Boarding

7.8

Entertainment

6.8

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Copa Airlines
7.5
Good
1,451 reviews
Copa Airlines
7.5
Good
1,451 reviews

Food

6.8

Boarding

7.8

Entertainment

6.8

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.5
Good
1,451 reviews

Food

6.8

Boarding

7.8

Entertainment

6.8

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Avianca
6.7
Okay
2,345 reviews
Copa Airlines
7.5
Good
1,451 reviews

Food

6.8

Boarding

7.8

Entertainment

6.8

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Spirit Airlines
6.3
Okay
8,052 reviews
Copa Airlines
7.5
Good
1,451 reviews

Food

6.8

Boarding

7.8

Entertainment

6.8

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santo Domingo to Cali round-trip?

    Flying on Copa Airlines is currently your cheapest option to Cali, with prices starting at $351. Additional round-trip tickets that might be worth considering are offered by Avianca and Spirit Airlines, with the lowest prices starting at $354 and $497, respectively.

  • Can I find deals for flights from Santo Domingo to Cali that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Cali.

  • Can I find deals for business class flights from Santo Domingo to Cali?

    Yes. Cheapflights offers flight deals from Santo Domingo to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Cali?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $351). Flying from Santo Domingo to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Santo Domingo to Cali

Discover the top 2 airlines that operate flights from Santo Domingo to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$323Average$350FlexibilityNo cancel feeOn-time70%
AviancaCheapest$325Average$359FlexibilityNo cancel feeOn-time71%

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