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$141+ Cheap flights from Santo Domingo (SDQ) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CLO
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl are usually found in September or January, booked 65 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Santo Domingo to Cali

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Cali (CLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$301
(Copa Airlines)

One-way from

$141
(Copa Airlines)

Popular in

October

Cheapest in

September

Average price

$410
Provider with most accurate pricing for Santo Domingo Las Americas-Cali Alfonso B. Aragon Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Cali Alfonso B. Aragon Intl flights.
Search Deals
From Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
Search Deals
One-way flight from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Santo Domingo to Cali

Cheapest flights from Santo Domingo to Cali
Explore the most affordable flight options available from Santo Domingo to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:39 pmSDQ - CLO
1 stop5h 58mCopa Airlines
Mon 11/178:48 amCLO - SDQ
1 stop12h 37mCopa Airlines
Deal found 10/28$301
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:08 pmSDQ - CLO
1 stop14h 03mMultiple Airlines
Mon 1/195:20 pmCLO - SDQ
1 stop6h 14mMultiple Airlines
Deal found 10/28$336
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:55 amSDQ - CLO
1 stop6h 34mCopa Airlines
Tue 12/163:11 pmCLO - SDQ
1 stop6h 45mCopa Airlines
Deal found 10/28$339
This Copa Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/611:55 amSDQ - CLO
1 stop6h 34mCopa Airlines
Sat 11/84:52 amCLO - SDQ
1 stop5h 06mCopa Airlines
Deal found 10/27$365
This Priceline deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2712:20 pmSDQ - CLO
1 stop8h 10mAvianca
Sun 11/307:55 amCLO - SDQ
1 stop7h 55mAvianca
Deal found 10/27$367
This Avianca deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/175:45 pmSDQ - CLO
1 stop6h 25mAvianca
Thu 11/208:40 amCLO - SDQ
1 stop7h 10mAvianca
Deal found 10/26$407
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/313:55 amSDQ - CLO
1 stop28h 19mMultiple Airlines
Sun 11/27:40 pmCLO - SDQ
1 stop27h 54mMultiple Airlines
Deal found 10/27$412

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Santo Domingo to Cali that are best for you.

Fly from

Santo Domingo

Fly to

Cali

Route

Depart

Return

Price

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Fri 11/14

2:15 pm-11:37 pm

1 stop10h 22m

Cali Alfonso B. Aragon Intl

Mon 11/17

3:12 pm-10:25 pm

1 stop6h 13m

$301

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Mon 11/10

8:55 am-2:11 pm

1 stop6h 16m

Cali Alfonso B. Aragon Intl

Mon 11/17

3:12 pm-2:26 am

1 stop10h 14m

$301

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Sat 1/17

8:50 am-5:37 pm

1 stop9h 47m

Cali Alfonso B. Aragon Intl

Thu 1/22

12:03 pm-10:55 pm

1 stop9h 52m

$301

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Mon 1/19

8:50 am-2:10 pm

1 stop6h 20m

Cali Alfonso B. Aragon Intl

Wed 1/21

12:03 pm-6:05 pm

1 stop5h 02m

$301

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Thu 3/12

11:56 am-5:49 pm

1 stop6h 53m

Cali Alfonso B. Aragon Intl

Sun 3/15

5:03 am-1:11 pm

1 stop7h 08m

$301

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Wed 11/26

8:55 am-5:29 pm

1 stop9h 34m

Cali Alfonso B. Aragon Intl

Sun 11/30

3:12 pm-10:25 pm

1 stop6h 13m

$301

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Sat 11/22

11:55 am-11:37 pm

1 stop12h 42m

Cali Alfonso B. Aragon Intl

Sat 11/29

8:48 am-10:25 pm

1 stop12h 37m

$301

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Sat 11/15

11:55 am-5:29 pm

1 stop6h 34m

Cali Alfonso B. Aragon Intl

Sat 11/22

12:04 pm-10:25 pm

1 stop9h 21m

$301

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Mon 11/10

8:55 am-5:29 pm

1 stop9h 34m

$141

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Sun 11/30

8:55 am-11:37 pm

1 stop15h 42m

$141

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 14 results
1
2

Compare providers for flights from Santo Domingo to Cali

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to Cali in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-Cali flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santo Domingo-Cali flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santo Domingo-Cali flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Cali flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Cali flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Cali

How far ahead should I book a flight from Santo Domingo to Cali?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Cali. Price data was last updated on October 24, 2025.

To ensure you get the cheapest price possible for a flight from Santo Domingo to Cali, you should look to book at least 65 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santo Domingo to Cali?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $250). Flying from Santo Domingo to Cali in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated October 28, 2025.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Santo Domingo to Cali to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,562 reviews

Crew

8.1

Boarding

7.8

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,562 reviews
Copa Airlines
7.6
Good
1,562 reviews

Crew

8.1

Boarding

7.8

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,468 reviews
Copa Airlines
7.6
Good
1,562 reviews

Crew

8.1

Boarding

7.8

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Cali?

    Airlines like Copa Airlines fly from Santo Domingo to Cali in about 10h 22m. The time it takes to get you to your destination can typically vary by up to . The distance from Santo Domingo to Cali is about 1123 mi.

  • What are the cheapest airlines flying from Santo Domingo to Cali round-trip?

    Flying on Copa Airlines is currently your cheapest option to Cali, with prices starting at $327. Another option worth looking into is Avianca, starting at $327 round trip. Copa Airlines is 7% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santo Domingo to Cali that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Cali.

  • Can I find deals for business class flights from Santo Domingo to Cali?

    Yes. Cheapflights offers flight deals from Santo Domingo to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Cali?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $250). Flying from Santo Domingo to Cali in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Santo Domingo to Cali

Discover the top 2 airlines that operate flights from Santo Domingo to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$327Average$350FlexibilityNo cancel feeOn-time70%
AviancaCheapest$327Average$356FlexibilityNo cancel feeOn-time71%

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