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$135+ Cheap flights from Santo Domingo (SDQ) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CLO
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl are usually found in September or January, booked 65 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Santo Domingo to Cali

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Cali (CLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$334
(Copa Airlines)

One-way from

$135
(Kiwi.com)

Popular in

October

Cheapest in

September

Average price

$334
From Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
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One-way flight from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
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Highest demand for flights based on searches. 1% potential increase in price ($5 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santo Domingo to Cali

Cheapest flights from Santo Domingo to Cali
Explore the most affordable flight options available from Santo Domingo to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:58 amSDQ - CLO
1 stop15h 37mCopa Airlines
Mon 11/312:04 pmCLO - SDQ
1 stop13h 22mCopa Airlines
Deal found 9/15$334
This Avianca deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:45 pmSDQ - CLO
1 stop6h 55mAvianca
Sun 11/98:20 amCLO - SDQ
1 stop7h 30mAvianca
Deal found 9/15$338
This Priceline deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:10 pmSDQ - CLO
1 stop5h 42mAvianca
Sun 9/287:52 amCLO - SDQ
1 stop8h 23mAvianca
Deal found 9/16$346
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/307:35 amSDQ - CLO
1 stop5h 53mMultiple Airlines
Mon 12/19:23 pmCLO - SDQ
1 stop15h 27mMultiple Airlines
Deal found 9/16$354
This Avianca deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:45 pmSDQ - CLO
1 stop6h 25mAvianca
Fri 11/149:50 amCLO - SDQ
1 stop6h 00mAvianca
Deal found 9/15$358
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/68:55 amSDQ - CLO
1 stop6h 16mCopa Airlines
Sat 11/84:52 amCLO - SDQ
1 stop5h 06mCopa Airlines
Deal found 9/16$421
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2511:45 amSDQ - CLO
1 stop6h 32mMultiple Airlines
Sun 9/288:13 amCLO - SDQ
2 stops13h 04mMultiple Airlines
Deal found 9/16$423
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:58 amSDQ - CLO
1 stop9h 31mCopa Airlines
Mon 11/34:52 amCLO - SDQ
1 stop10h 23mCopa Airlines
Deal found 9/16$443

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Santo Domingo to Cali that are best for you.

Fly from

Santo Domingo

Fly to

Cali

Route

Depart

Return

Price

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Wed 10/29

8:58 am-11:35 pm

1 stop15h 37m

Cali Alfonso B. Aragon Intl

Mon 11/3

12:04 pm-2:26 am

1 stop13h 22m

$334

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Fri 11/7

5:45 pm-11:40 pm

1 stop6h 55m

Cali Alfonso B. Aragon Intl

Sun 11/9

8:20 am-4:50 pm

1 stop7h 30m

$338

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Fri 10/31

5:45 pm-11:10 pm

1 stop6h 25m

Cali Alfonso B. Aragon Intl

Fri 11/14

9:50 am-4:50 pm

1 stop6h 00m

$358

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Sun 11/30

7:35 am-12:28 pm

1 stop5h 53m

Cali Alfonso B. Aragon Intl

Mon 12/1

10:50 pm-1:49 pm

2 stops13h 59m

$385

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Thu 11/6

11:55 am-5:29 pm

1 stop6h 34m

Cali Alfonso B. Aragon Intl

Sat 11/8

4:52 am-10:58 am

1 stop5h 06m

$421

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Sat 10/18

2:10 am-7:15 am

1 stop6h 05m

$135

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Sun 10/19

7:40 am-8:28 am

1 stop25h 48m

$141

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Mon 11/10

5:45 pm-11:10 pm

1 stop6h 25m

$162

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Sun 11/30

6:00 am-2:11 pm

1 stop9h 11m

$179

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Wed 10/15

4:25 pm-6:38 am

1 stop15h 13m

$196

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Santo Domingo to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Cali

How far ahead should I book a flight from Santo Domingo to Cali?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Cali. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from Santo Domingo to Cali, you should look to book at least 65 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santo Domingo to Cali?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $351). Flying from Santo Domingo to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated September 17, 2025.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Santo Domingo to Cali to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,533 reviews

Overall

7.6

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Crew

8.1

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,533 reviews
Copa Airlines
7.6
Good
1,533 reviews

Overall

7.6

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Crew

8.1

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,436 reviews
Copa Airlines
7.6
Good
1,533 reviews

Overall

7.6

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Crew

8.1

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Cali?

    Airlines like Copa Airlines and Avianca fly from Santo Domingo to Cali in about 6h 55m. The time it takes to get you to your destination can typically vary by up to 8h 42m. The distance from Santo Domingo to Cali is about 1123 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Santo Domingo to Cali round-trip?

    Flying on Copa Airlines is currently your cheapest option to Cali, with prices starting at $327. Another option worth looking into is Avianca, starting at $327 round trip. Copa Airlines is 7% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santo Domingo to Cali that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Cali.

  • Can I find deals for business class flights from Santo Domingo to Cali?

    Yes. Cheapflights offers flight deals from Santo Domingo to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Cali?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $351). Flying from Santo Domingo to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Santo Domingo to Cali

Discover the top 2 airlines that operate flights from Santo Domingo to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$327Average$350FlexibilityNo cancel feeOn-time70%
AviancaCheapest$327Average$369FlexibilityNo cancel feeOn-time71%

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