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$141+ Cheap flights from Santo Domingo (SDQ) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CLO
Dec 11 — Dec 181
Thu 12/11
Thu 12/18
1 adult, Economy
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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl are usually found in September or January, booked 49 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Santo Domingo to Cali

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Cali (CLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 11, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$301
(Copa Airlines)

One-way from

$141
(Copa Airlines)

Popular in

October

Cheapest in

September

Average price

$353
Provider with most accurate pricing for Santo Domingo Las Americas-Cali Alfonso B. Aragon Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Cali Alfonso B. Aragon Intl flights.
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From Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
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One-way flight from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
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Highest demand for flights based on searches. 1% potential increase in price ($5 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Santo Domingo to Cali

Cheapest flights from Santo Domingo to Cali
Explore the most affordable flight options available from Santo Domingo to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 11, 2025.

This Copa Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:00 amSDQ - CLO
1 stop9h 11mCopa Airlines
Mon 12/112:04 pmCLO - SDQ
1 stop13h 22mCopa Airlines
Deal found 11/10$301
This Copa Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:55 amSDQ - CLO
1 stop15h 42mCopa Airlines
Wed 12/173:11 pmCLO - SDQ
1 stop6h 45mCopa Airlines
Deal found 11/10$339
This Copa Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/268:55 amSDQ - CLO
1 stop6h 16mCopa Airlines
Tue 12/165:01 amCLO - SDQ
1 stop7h 11mCopa Airlines
Deal found 11/9$389
This Avianca deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:45 pmSDQ - CLO
1 stop14h 25mAvianca
Wed 1/78:20 amCLO - SDQ
1 stop7h 30mAvianca
Deal found 11/11$405
This Priceline deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:45 pmSDQ - CLO
1 stop6h 25mAvianca
Thu 1/15:05 amCLO - SDQ
1 stop5h 20mAvianca
Deal found 11/10$422
This Copa Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1011:55 amSDQ - CLO
1 stop6h 34mCopa Airlines
Mon 11/173:12 pmCLO - SDQ
1 stop10h 14mCopa Airlines
Deal found 11/9$428
This Avianca deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/285:45 pmSDQ - CLO
1 stop13h 25mAvianca
Mon 12/110:15 amCLO - SDQ
1 stop5h 35mAvianca
Deal found 11/10$430
This Avianca deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:20 pmSDQ - CLO
1 stop8h 35mAvianca
Mon 12/298:20 amCLO - SDQ
1 stop7h 30mAvianca
Deal found 11/10$463
This Copa Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:55 amSDQ - CLO
1 stop6h 34mCopa Airlines
Wed 11/194:52 amCLO - SDQ
1 stop10h 23mCopa Airlines
Deal found 11/9$491
This Avianca deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:45 pmSDQ - CLO
1 stop14h 00mAvianca
Mon 12/298:20 amCLO - SDQ
1 stop7h 30mAvianca
Deal found 11/9$510

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 11, 2025.
Use the filters below to find and compare flights from Santo Domingo to Cali that are best for you.

Fly from

Santo Domingo

Fly to

Cali

Route

Depart

Return

Price

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Mon 2/9

8:50 am-2:10 pm

1 stop6h 20m

Cali Alfonso B. Aragon Intl

Thu 2/12

3:11 pm-10:39 pm

1 stop6h 28m

$301

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Fri 12/12

8:55 am-2:11 pm

1 stop6h 16m

Cali Alfonso B. Aragon Intl

Sat 1/17

12:03 pm-6:05 pm

1 stop5h 02m

$301

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Thu 11/27

6:00 am-2:11 pm

1 stop9h 11m

Cali Alfonso B. Aragon Intl

Mon 12/1

12:04 pm-2:26 am

1 stop13h 22m

$301

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Mon 2/9

7:25 pm-9:37 am

2 stops15h 12m

Cali Alfonso B. Aragon Intl

Thu 2/12

9:22 pm-1:55 pm

1 stop15h 33m

$334

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Wed 12/10

8:55 am-11:37 pm

1 stop15h 42m

Cali Alfonso B. Aragon Intl

Wed 12/17

3:11 pm-10:56 pm

1 stop6h 45m

$339

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Wed 11/26

8:55 am-2:11 pm

1 stop6h 16m

Cali Alfonso B. Aragon Intl

Tue 12/16

5:01 am-1:12 pm

1 stop7h 11m

$389

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Mon 4/6

12:10 pm-5:37 pm

1 stop6h 27m

Cali Alfonso B. Aragon Intl

Fri 4/10

5:03 am-1:09 pm

1 stop7h 06m

$403

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Wed 12/17

5:45 pm-6:45 am

1 stop14h 00m

Cali Alfonso B. Aragon Intl

Wed 1/7

8:20 am-4:50 pm

1 stop7h 30m

$405

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Wed 12/10

12:40 pm-11:37 pm

1 stop11h 57m

$141

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Thu 12/25

12:20 pm-11:10 pm

1 stop11h 50m

$183

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/8

Showing 1-10 of 11 results
1
2

Compare providers for flights from Santo Domingo to Cali

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to Cali in November.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-Cali flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santo Domingo-Cali flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santo Domingo-Cali flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Cali flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Cali flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Cali

How far ahead should I book a flight from Santo Domingo to Cali?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Cali. Price data was last updated on November 7, 2025.

To ensure you get the cheapest price possible for a flight from Santo Domingo to Cali, you should look to book at least 49 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santo Domingo to Cali?

Currently, November is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $194). Flying from Santo Domingo to Cali in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated November 11, 2025.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Santo Domingo to Cali to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,562 reviews

Comfort

7.4

Food

6.9

Entertainment

6.8

Boarding

7.8

Crew

8.1

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,562 reviews
Copa Airlines
7.6
Good
1,562 reviews

Comfort

7.4

Food

6.9

Entertainment

6.8

Boarding

7.8

Crew

8.1

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,473 reviews
Copa Airlines
7.6
Good
1,562 reviews

Comfort

7.4

Food

6.9

Entertainment

6.8

Boarding

7.8

Crew

8.1

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Cali?

    Airlines like Copa Airlines fly from Santo Domingo to Cali in about 6h 20m. The time it takes to get you to your destination can typically vary by up to . The distance from Santo Domingo to Cali is about 1123 mi.

  • What are the cheapest airlines flying from Santo Domingo to Cali round-trip?

    Flying on Copa Airlines is currently your cheapest option to Cali, with prices starting at $327. Another option worth looking into is Avianca, starting at $327 round trip. Copa Airlines is 7% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Santo Domingo to Cali one-way?

    One-way options have recently been found by users for as low as $141 on Copa Airlines. Other airlines that offer cheap prices include Avianca from $183 and Spirit Airlines from $346 one-way.

  • Can I find deals for flights from Santo Domingo to Cali that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Cali.

  • Can I find deals for business class flights from Santo Domingo to Cali?

    Yes. Cheapflights offers flight deals from Santo Domingo to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Cali?

    Currently, November is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $194). Flying from Santo Domingo to Cali in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Santo Domingo to Cali

Discover the top 2 airlines that operate flights from Santo Domingo to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$327Average$350FlexibilityNo cancel feeOn-time70%
AviancaCheapest$327Average$356FlexibilityNo cancel feeOn-time71%

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