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$141+ Cheap flights from Santo Domingo (SDQ) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CLO
ago. 25 — sep. 11
lun. 8/25
lun. 9/1
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl are usually found in September or January, booked 65 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Santo Domingo to Cali

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Cali (CLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated agosto 20, 2025.

Round-trip from

$332
(Copa Airlines)

One-way from

$141
(Kiwi.com)

Popular in

October

Cheapest in

September

Average price

$350
From Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
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One-way flight from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Santo Domingo to Cali

Cheapest flights from Santo Domingo to Cali
Explore the most affordable flight options available from Santo Domingo to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 20, 2025.

This Copa Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/308:57 amSDQ - CLO
1 stop6h 24mCopa Airlines
mar. 9/24:42 amCLO - SDQ
1 stop10h 35mCopa Airlines
Deal found 8/18$332
This Copa Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/2912:00 pmSDQ - CLO
1 stop12h 35mCopa Airlines
lun. 11/312:04 pmCLO - SDQ
1 stop13h 22mCopa Airlines
Deal found 8/18$333
This Avianca deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/75:45 pmSDQ - CLO
1 stop6h 55mAvianca
dom. 11/910:15 amCLO - SDQ
1 stop5h 35mAvianca
Deal found 8/19$337
This Avianca deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/315:45 pmSDQ - CLO
1 stop6h 55mAvianca
vie. 11/1410:55 amCLO - SDQ
1 stop4h 55mAvianca
Deal found 8/18$357
This Copa Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/1811:56 amSDQ - CLO
1 stop12h 26mCopa Airlines
lun. 9/224:42 amCLO - SDQ
1 stop5h 16mCopa Airlines
Deal found 8/19$374
This Avianca deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/206:10 pmSDQ - CLO
1 stop6h 34mAvianca
dom. 8/319:14 amCLO - SDQ
1 stop7h 01mAvianca
Deal found 8/18$381
This Priceline deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/75:45 pmSDQ - CLO
1 stop13h 25mAvianca
lun. 11/108:40 amCLO - SDQ
1 stop7h 10mAvianca
Deal found 8/19$392
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/75:45 pmSDQ - CLO
1 stop6h 55mMultiple Airlines
lun. 11/1010:08 pmCLO - SDQ
2 stops12h 17mMultiple Airlines
Deal found 8/19$393
This Avianca deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/175:45 pmSDQ - CLO
1 stop13h 25mAvianca
mié. 1/710:15 amCLO - SDQ
1 stop5h 35mAvianca
Deal found 8/18$421

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 20, 2025.
Use the filters below to find and compare flights from Santo Domingo to Cali that are best for you.

Fly from

Santo Domingo

Fly to

Cali

Route

Depart

Return

Price

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

sáb. 8/30

8:57 am-2:21 pm

1 stop6h 24m

Cali Alfonso B. Aragon Intl

mar. 9/2

4:42 am-4:17 pm

1 stop10h 35m

$332

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

mié. 10/1

8:58 am-5:29 pm

1 stop9h 31m

Cali Alfonso B. Aragon Intl

jue. 10/2

4:40 am-1:07 pm

1 stop7h 27m

$332

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

vie. 9/19

6:17 pm-11:22 pm

1 stop6h 05m

Cali Alfonso B. Aragon Intl

lun. 9/22

3:23 pm-2:36 am

1 stop10h 13m

$332

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

lun. 9/8

11:56 am-5:25 pm

1 stop6h 29m

Cali Alfonso B. Aragon Intl

dom. 9/14

3:23 pm-10:26 pm

1 stop6h 03m

$332

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

mar. 9/30

5:25 am-10:58 am

1 stop6h 33m

Cali Alfonso B. Aragon Intl

jue. 10/2

8:47 am-4:15 pm

1 stop6h 28m

$332

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

jue. 9/18

5:25 am-10:58 am

1 stop6h 33m

Cali Alfonso B. Aragon Intl

lun. 9/22

8:48 am-10:26 pm

1 stop12h 38m

$332

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

mié. 10/29

12:00 pm-11:35 pm

1 stop12h 35m

Cali Alfonso B. Aragon Intl

lun. 11/3

12:04 pm-2:26 am

1 stop13h 22m

$333

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

vie. 11/7

5:45 pm-6:10 am

1 stop13h 25m

Cali Alfonso B. Aragon Intl

dom. 11/9

10:15 am-4:50 pm

1 stop5h 35m

$337

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

vie. 10/31

5:45 pm-11:40 pm

1 stop6h 55m

Cali Alfonso B. Aragon Intl

vie. 11/14

10:55 am-4:50 pm

1 stop4h 55m

$357

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

dom. 2/8

7:35 am-12:28 pm

1 stop5h 53m

Cali Alfonso B. Aragon Intl

sáb. 2/14

8:22 am-6:41 pm

1 stop9h 19m

$364

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/20

Showing 1-10 of 15 results
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Best time to book a flight from Santo Domingo to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Cali

How far ahead should I book a flight from Santo Domingo to Cali?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Cali. Price data was last updated on August 8, 2025.

To ensure you get the cheapest price possible for a flight from Santo Domingo to Cali, you should look to book at least 65 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santo Domingo to Cali?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $351). Flying from Santo Domingo to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santo Domingo to Cali?

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated agosto 20, 2025.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Santo Domingo to Cali to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,510 reviews

Food

6.8

Entertainment

6.8

Boarding

7.8

Crew

8.1

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Copa Airlines
7.5
Good
1,510 reviews
Copa Airlines
7.5
Good
1,510 reviews

Food

6.8

Entertainment

6.8

Boarding

7.8

Crew

8.1

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Avianca
6.7
Okay
2,411 reviews
Copa Airlines
7.5
Good
1,510 reviews

Food

6.8

Entertainment

6.8

Boarding

7.8

Crew

8.1

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Cali?

    Airlines like Copa Airlines fly from Santo Domingo to Cali in about 6h 24m. The time it takes to get you to your destination can typically vary by up to . The distance from Santo Domingo to Cali is about 1123 mi.

  • What are the cheapest airlines flying from Santo Domingo to Cali round-trip?

    Flying on Copa Airlines is currently your cheapest option to Cali, with prices starting at $323. Another option worth looking into is Avianca, starting at $327 round trip. Copa Airlines is 8% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santo Domingo to Cali that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Cali.

  • Can I find deals for business class flights from Santo Domingo to Cali?

    Yes. Cheapflights offers flight deals from Santo Domingo to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Cali?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $351). Flying from Santo Domingo to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Santo Domingo to Cali

Discover the top 2 airlines that operate flights from Santo Domingo to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$323Average$350FlexibilityNo cancel feeOn-time70%
AviancaCheapest$327Average$373FlexibilityNo cancel feeOn-time71%

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