What are the cheapest airlines flying from Mexico City to Cali round-trip?

Flying on Copa Airlines is currently your cheapest option to Cali, with prices starting at $270. Additional round-trip tickets that might be worth considering are offered by Aeromexico and Avianca, with the lowest prices starting at $273 and $297, respectively. Copa Airlines is currently priced 26% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Mexico City to Cali one-way?

The cheapest airlines for a one-way flight from Mexico City to Cali are Avianca ($144), Copa Airlines ($182), and Aeromexico ($259).

What is the cheapest day to fly from Mexico City to Cali?

Travelers seeking maximum savings on their Mexico City to Cali flight should consider departing on Friday mornings when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Cali ranges from 1.2 - 5.5 inches per month. April is typically the wettest month, when rainfall can reach 5.5 in. July is typically the driest time to visit Cali when rainfall is around 1.2 in.

If weather is an important factor for your trip to Cali, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What are the cheapest flights from Mexico City to Cali?

Looking at all options, your cheapest flight can be booked for $258. While the most popular route (Mexico City Benito Juarez - Cali Alfonso B. Aragon Intl) can be booked for $332 on average our data indicates $286 when flying from Mexico City to Cali.

What are the most popular airlines that fly from Mexico City to Cali?

Aeromexico, Avianca and Copa Airlines are the most popular airlines when flying from Mexico City to Cali.

What is the cheapest day to fly round-trip from Mexico City to Cali?

Travelers have found that booking a Sunday departure is the best way to save up to 2% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

How far in advance should I book a flight from Mexico City to Cali?

To save on the cost of your flight from Mexico City to Cali, book at least 17 days before your planned departure. Booking around this time can save you about 64% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $400 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $458.

What is the cheapest month to fly from Mexico City to Cali?

Flights from Mexico City to Cali lean towards being more expensive in December. Prices are generally better when you fly from Mexico City to Cali in May, with the cheapest ticket starting at $264.

Can I find deals for flights from Mexico City to Cali that include hotel bookings?

Yes. In addition to deals on Mexico City to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mexico City to Cali?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Cali.

Can I find deals for business class flights from Mexico City to Cali?

Yes. Cheapflights offers flight deals from Mexico City to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$144+ Flights from Mexico City to Cali

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Mexico City Benito Juarez to Cali Alfonso B. Aragon Intl are usually found in May or July, booked 86 days in advance, depart on a Monday or Tuesday and return on a Tuesday

Cheap flight deals from Mexico City to Cali

Round-trip from	$270 (Copa Airlines)
One-way from	$144 (Kiwi.com)
Popular in	December
Cheapest in	May
Average price	$324
Good one-way deal	$258 or less

From Mexico City Benito Juarez to Cali Alfonso B. Aragon Intl

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One-way flight from Mexico City Benito Juarez to Cali Alfonso B. Aragon Intl

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Highest demand for flights based on searches. 15% potential increase in price ($68 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

Search Deals

Price to beat on a one-way flight from Mexico City Benito Juarez to Cali Alfonso B. Aragon Intl.

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Find flight deals from Mexico City to Cali

Cheapest flights from Mexico City to Cali
Explore the most affordable flight options available from Mexico City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Sun 9/71:40 amMEX - CLO

1 stop11h 41mCopa Airlines

Wed 10/812:01 pmCLO - MEX

1 stop13h 59mCopa Airlines

Deal found 7/28

$270

Sat 9/131:05 pmMEX - CLO

Nonstop4h 54mAeromexico

Sat 9/208:30 amCLO - MEX

Nonstop4h 35mAeromexico

Deal found 7/30

$273

Sat 8/304:55 amMEX - CLO

1 stop7h 43mAvianca

Fri 9/58:27 pmCLO - MEX

1 stop7h 38mAvianca

Deal found 7/30

$297

Fri 8/2912:40 amMEX - CLO

2 stops17h 24mMultiple Airlines

Fri 9/57:24 pmCLO - MEX

1 stop8h 41mMultiple Airlines

Deal found 7/29

$401

Sat 12/204:00 pmMEX - CLO

2 stops23h 30mLATAM Airlines

Sun 1/111:35 pmCLO - MEX

2 stops25h 15mLATAM Airlines

Deal found 7/29

$417

Best flights from Mexico City to Cali
Discover carefully curated flight deals from Mexico City to Cali that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2025.

Sun 9/72:00 amMEX - CLO

1 stop7h 58mCopa Airlines

Wed 10/83:23 pmCLO - MEX

1 stop9h 52mCopa Airlines

Deal found 7/30

$270

Sat 9/131:05 pmMEX - CLO

Nonstop4h 54mAeromexico

Sat 9/208:30 amCLO - MEX

Nonstop4h 35mAeromexico

Deal found 7/30

$273

Sat 8/304:55 amMEX - CLO

1 stop7h 43mAvianca

Fri 9/58:27 pmCLO - MEX

1 stop7h 38mAvianca

Deal found 7/30

$297

Fri 8/2912:40 amMEX - CLO

2 stops17h 24mMultiple Airlines

Fri 9/57:24 pmCLO - MEX

1 stop8h 41mMultiple Airlines

Deal found 7/29

$401

Sat 12/204:00 pmMEX - CLO

2 stops23h 30mLATAM Airlines

Sun 1/111:35 pmCLO - MEX

2 stops25h 15mLATAM Airlines

Deal found 7/29

$417

Last-minute flights from Mexico City to Cali
Discover last-minute flight deals from Mexico City to Cali. Data last updated July 30, 2025 and is based on user searches.

Mon 8/49:50 amMEX - CLO

1 stop6h 35mCopa Airlines

Mon 8/2512:01 pmCLO - MEX

1 stop13h 14mCopa Airlines

Deal found 7/29

$424

Wed 8/61:15 pmMEX - CLO

Nonstop4h 39mAeromexico

Wed 8/138:31 amCLO - MEX

Nonstop4h 34mAeromexico

Deal found 7/29

$360

Fri 8/84:55 amMEX - CLO

1 stop8h 25mAvianca

Fri 10/104:24 amCLO - MEX

1 stop8h 41mAvianca

Deal found 7/30

$407

Fri 8/83:10 pmMEX - CLO

2 stops15h 19mLATAM Airlines

Fri 10/102:26 pmCLO - MEX

2 stops24h 24mLATAM Airlines

Deal found 7/30

$730

Wed 8/134:40 amMEX - CLO

2 stops11h 45mUnited Airlines

Fri 8/154:42 amCLO - MEX

2 stops11h 58mUnited Airlines

Deal found 7/29

$2,997

Fri 8/225:50 amMEX - CLO

1 stop7h 31mCopa Airlines

Fri 9/193:23 pmCLO - MEX

1 stop10h 37mCopa Airlines

Deal found 7/27

$270

Fri 8/221:15 pmMEX - CLO

Nonstop4h 39mAeromexico

Tue 8/268:31 amCLO - MEX

Nonstop4h 24mAeromexico

Deal found 7/29

$308

Fri 8/2211:20 amMEX - CLO

2 stops25h 00mAmerican Airlines

Tue 8/262:20 pmCLO - MEX

1 stop20h 35mAmerican Airlines

Deal found 7/28

$2,557

Fri 8/2912:40 amMEX - CLO

2 stops17h 24mMultiple Airlines

Fri 9/57:24 pmCLO - MEX

1 stop8h 41mMultiple Airlines

Deal found 7/29

$401

Sat 8/304:55 amMEX - CLO

1 stop7h 43mAvianca

Fri 9/58:27 pmCLO - MEX

1 stop7h 38mAvianca

Deal found 7/30

$297

Sat 8/303:10 pmMEX - CLO

2 stops22h 33mLATAM Airlines

Fri 9/53:37 pmCLO - MEX

2 stops23h 13mLATAM Airlines

Deal found 7/30

$559

One-way flights from Mexico City to Cali
Search for one-way flight options from Mexico City to Cali. Find affordable one-way fares based on user searches. Data last updated July 30, 2025.

Tue 8/1211:20 pmMEX - CLO

1 stop7h 15mAvianca

Deal found 7/28

$144

Mon 8/41:40 amMEX - CLO

1 stop11h 41mCopa Airlines

Deal found 7/30

$182

Sun 9/712:40 amMEX - CLO

2 stops29h 30mMultiple Airlines

Deal found 7/28

$192

Sat 8/2312:50 pmMEX - CLO

Nonstop4h 39mAeromexico

Deal found 7/30

$259

Fly from

Fly to

Route

Depart

Return

Price

Mexico CityCali

MEX - CLO

MEXCLO

Mexico City Benito Juarez

Sun 9/7

2:00 am-10:58 am

1 stop7h 58m

Cali Alfonso B. Aragon Intl

Wed 10/8

3:23 pm-12:15 am

1 stop9h 52m

$270

Mexico CityCali

MEX - CLO

MEXCLO

Mexico City Benito Juarez

Sat 9/13

1:05 pm-6:59 pm

Nonstop4h 54m

Cali Alfonso B. Aragon Intl

Sat 9/20

8:30 am-12:05 pm

Nonstop4h 35m

$273

Mexico CityCali

MEX - CLO

MEXCLO

Mexico City Benito Juarez

Sat 8/30

4:55 am-1:38 pm

1 stop7h 43m

Cali Alfonso B. Aragon Intl

Fri 9/5

8:27 pm-3:05 am

1 stop7h 38m

$297

Mexico CityCali

MEX - CLO

MEXCLO

Mexico City Benito Juarez

Fri 8/29

12:40 am-7:04 pm

2 stops17h 24m

Cali Alfonso B. Aragon Intl

Fri 9/5

7:24 pm-3:05 am

1 stop8h 41m

$401

Mexico CityCali

MEX - CLO

MEXCLO

Mexico City Benito Juarez

Sat 12/20

4:00 pm-4:30 pm

2 stops23h 30m

Cali Alfonso B. Aragon Intl

Sun 1/11

1:35 pm-1:50 pm

2 stops25h 15m

$417

Mexico CityCali

MEX - CLO

MEXCLO

Mexico City Benito Juarez

Tue 8/12

11:20 pm-7:35 am

1 stop7h 15m

$144

Mexico CityCali

MEX - CLO

MEXCLO

Mexico City Benito Juarez

Mon 8/4

1:40 am-2:21 pm

1 stop11h 41m

$182

Mexico CityCali

MEX - CLO

MEXCLO

Mexico City Benito Juarez

Sun 9/7

12:40 am-7:10 am

2 stops29h 30m

$192

Mexico CityCali

MEX - CLO

MEXCLO

Mexico City Benito Juarez

Sat 8/23

12:50 pm-6:29 pm

Nonstop4h 39m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Mexico City to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Mexico City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Cali

How far ahead should I book a flight from Mexico City to Cali?

The best time to book flights from Mexico City to Cali is 86 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Mexico City to Cali?

Currently, January is the cheapest month in which you can book a flight from Mexico City to Cali (average of $351). Flying from Mexico City to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to CLO?

It’s optimal to fly from Mexico City to Cali in the morning. By choosing this option you can save up to 29% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Cali

Peruse reviews from past customers who have flown with LATAM Airlines, Copa Airlines, and Aeromexico from Mexico City to Cali to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

LATAM Airlines

7.5

Good

1,822 reviews

Reviews

1 / 20

4.0

Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.

LATAM Airlines

7.5

Good

1,822 reviews

LATAM Airlines

7.5

Good

1,822 reviews

Reviews

1 / 20

4.0

Okay

Duane,Jun 2025

GRU - MAD

Copa Airlines

7.5

Good

1,493 reviews

LATAM Airlines

7.5

Good

1,822 reviews

Reviews

1 / 20

4.0

Okay

Duane,Jun 2025

GRU - MAD

Aeromexico

7.5

Good

1,721 reviews

LATAM Airlines

7.5

Good

1,822 reviews

Reviews

1 / 20

4.0

Okay

Duane,Jun 2025

GRU - MAD

Avianca

6.7

Okay

2,387 reviews

LATAM Airlines

7.5

Good

1,822 reviews

Reviews

1 / 20

4.0

Okay

Duane,Jun 2025

GRU - MAD

Related info for your journey

What are the cheapest airlines flying from Mexico City to Cali round-trip?
Flying on Copa Airlines is currently your cheapest option to Cali, with prices starting at $270. Additional round-trip tickets that might be worth considering are offered by Aeromexico and Avianca, with the lowest prices starting at $273 and $297, respectively. Copa Airlines is currently priced 26% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Mexico City to Cali one-way?
The cheapest airlines for a one-way flight from Mexico City to Cali are Avianca ($144), Copa Airlines ($182), and Aeromexico ($259).
What are the cheapest flights from Mexico City to Cali?
Looking at all options, your cheapest flight can be booked for $258. While the most popular route (Mexico City Benito Juarez - Cali Alfonso B. Aragon Intl) can be booked for $332 on average our data indicates $286 when flying from Mexico City to Cali.
Can I find deals for flights from Mexico City to Cali that include hotel bookings?
Yes. In addition to deals on Mexico City to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mexico City to Cali?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Cali.
Can I find deals for business class flights from Mexico City to Cali?
Yes. Cheapflights offers flight deals from Mexico City to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Mexico City to Cali?
Currently, January is the cheapest month in which you can book a flight from Mexico City to Cali (average of $351). Flying from Mexico City to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Mexico City to Cali

Mexico City to Jose Maria Cordova Intl flights

Mexico City to Bogotá flights

Mexico City to Cartagena flights

Mexico City to Barranquilla flights

Mexico City to Armenia flights

Mexico City to Pereira flights

Other flights to Cali

Top 3 airlines flying from Mexico City to Cali

Airline	Cheapest	Average	Flexibility	On-time
Aeromexico	Cheapest$169	Average$304	FlexibilityNo cancel fee	On-timeN/A
Copa Airlines	Cheapest$286	Average$416	FlexibilityNo cancel fee	On-time70%
Avianca	Cheapest$288	Average$436	FlexibilityNo cancel fee	On-time71%

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$144+ Cheap flights from Mexico City (MEX) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Mexico City to Cali with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Mexico City Benito Juarez to Cali Alfonso B. Aragon Intl are usually found in May or July, booked 86 days in advance, depart on a Monday or Tuesday and return on a Tuesday

Cheap flight deals from Mexico City to Cali

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good one-way deal

Find flight deals from Mexico City to Cali

Cheapest flights from Mexico City to CaliExplore the most affordable flight options available from Mexico City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Explore the most affordable flight options available from Mexico City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mexico City to Cali that are best for you.

Best time to book a flight from Mexico City to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Mexico City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Cali

How far ahead should I book a flight from Mexico City to Cali?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Cali. Price data was last updated on July 25, 2025.

What is the cheapest month to book a flight from Mexico City to Cali?

What is the cheapest time of day to fly from MEX to CLO?

Find hourly flight availability from Mexico City to Cali. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated July 30, 2025.

Peruse reviews from past customers who have flown with LATAM Airlines, Copa Airlines, and Aeromexico from Mexico City to Cali to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Mexico City to Cali round-trip?

What are the cheapest airlines to fly from Mexico City to Cali one-way?

What are the cheapest flights from Mexico City to Cali?

Can I find deals for flights from Mexico City to Cali that include hotel bookings?

How can I find direct flights from Mexico City to Cali?

Can I find deals for business class flights from Mexico City to Cali?

What is the cheapest month to book a flight from Mexico City to Cali?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mexico City to Cali

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Mexico City to Cali

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Cheapest flights from Mexico City to Cali
Explore the most affordable flight options available from Mexico City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.