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$197+ Cheap flights from the Cayman Islands to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — BUF
Mar 9 — Mar 161
Mon 3/9
Mon 3/16
1 adult, Economy
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Cheap flight deals from Cayman Islands to Buffalo

One-way flights from Cayman Islands to Buffalo
Search for one-way flight options from Cayman Islands to Buffalo. Find affordable one-way fares based on user searches. Data last updated February 7, 2026.

This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:50 pm
GCM
-
BUF
1 stop29h 53m
United Airlines
Deal found 2/4$197
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1911:40 am
GCM
-
BUF
2 stops23h 09m
American Airlines
Deal found 2/4$241
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:40 pm
GCM
-
BUF
3 stops18h 07m
Multiple Airlines
Deal found 2/4$291
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2512:45 pm
GCM
-
BUF
1 stop8h 50m
Southwest
Deal found 2/3$332
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/201:25 pm
GCM
-
BUF
2 stops30h 21m
United Airlines
Deal found 2/4$333
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:50 pm
GCM
-
BUF
1 stop25h 52m
United Airlines
Deal found 2/4$341
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/211:00 pm
GCM
-
BUF
1 stop10h 14m
Delta
Deal found 2/4$373
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:45 am
GCM
-
BUF
2 stops14h 46m
American Airlines
Deal found 2/4$378
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/212:35 pm
GCM
-
BUF
2 stops19h 23m
American Airlines
Deal found 2/4$531

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cayman Islands to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from the Cayman Islands to Buffalo that are best for you.

Fly from

Cayman Islands

Fly to

Buffalo

Route

Depart

Return

Price

George TownBuffalo

GCM - BUF

GCMBUF

George Town Owen Roberts Intl

Thu 4/16

1:50 pm-8:43 pm

1 stop29h 53m

$197

George TownBuffalo

GCM - BUF

GCMBUF

George Town Owen Roberts Intl

Fri 4/17

1:50 pm-8:49 pm

1 stop29h 59m

$197

George TownBuffalo

GCM - BUF

GCMBUF

George Town Owen Roberts Intl

Thu 3/19

11:40 am-11:49 am

2 stops23h 09m

$241

George TownBuffalo

GCM - BUF

GCMBUF

George Town Owen Roberts Intl

Thu 6/25

12:45 pm-10:35 pm

1 stop8h 50m

$332

George TownBuffalo

GCM - BUF

GCMBUF

George Town Owen Roberts Intl

Fri 3/20

1:25 pm-8:46 pm

2 stops30h 21m

$333

George TownBuffalo

GCM - BUF

GCMBUF

George Town Owen Roberts Intl

Thu 6/25

1:35 pm-9:02 pm

2 stops30h 27m

$333

George TownBuffalo

GCM - BUF

GCMBUF

George Town Owen Roberts Intl

Thu 3/19

1:50 pm-4:42 pm

1 stop25h 52m

$341

George TownBuffalo

GCM - BUF

GCMBUF

George Town Owen Roberts Intl

Sat 3/21

1:00 pm-12:14 am

1 stop10h 14m

$373

George TownBuffalo

GCM - BUF

GCMBUF

George Town Owen Roberts Intl

Fri 3/20

7:45 am-11:31 pm

2 stops14h 46m

$378

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/4

Best time to book a flight from Cayman Islands to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Cayman Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the Cayman Islands to Buffalo
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Cayman Islands to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Cayman Islands?

    Located just 8.3 mi from the city center, Buffalo (BUF) is the airport most travelers will use when flying to Buffalo from Cayman Islands.

  • Can I find deals for flights from Cayman Islands to Buffalo that include hotel bookings?

    Yes. In addition to deals on Cayman Islands to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cayman Islands to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cayman Islands to Buffalo.

  • Can I find deals for business class flights from Cayman Islands to Buffalo?

    Yes. Cheapflights offers flight deals from Cayman Islands to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

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