$407+ Cheap flights from Buffalo (BUF) to the Cayman Islands
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
Nov 3 — Nov 101
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Cayman Islands with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Cayman Islands
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Best
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Cheapest flights from Buffalo to Cayman IslandsExplore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
Explore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:00 am -
1 stop5h 58m
Sun 12/272:27 pm -
1 stop9h 28m
Deal found 9/30![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:52 pm -
1 stop16h 34m
Wed 12/1612:21 pm -
1 stop9h 38m
Deal found 9/29![American Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:44 pm -
1 stop16h 47m
Tue 12/291:06 pm -
1 stop10h 00m
Deal found 9/30![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:35 am -
1 stop10h 10m
Mon 12/2112:42 pm -
2 stops26h 29m
Deal found 9/30![American Airlines logo]()
$501
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:49 pm -
2 stops19h 46m
Mon 12/213:30 pm -
1 stop19h 10m
Deal found 9/30![American Airlines logo]()
$507
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:00 am -
2 stops14h 01m
Sun 12/273:20 pm -
1 stop8h 23m
Deal found 9/30![American Airlines logo]()
$511
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:00 am -
1 stop6h 25m
Sat 12/2612:55 pm -
1 stop11h 07m
Deal found 9/30![Delta logo]()
$519
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/212:50 pm -
1 stop25h 45m
Thu 12/245:45 pm -
2 stops27h 02m
Deal found 9/30![United Airlines logo]()
$537
Best flights from Buffalo to Cayman IslandsDiscover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
Discover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:36 pm -
1 stop15h 50m
Thu 12/171:06 pm -
1 stop10h 00m
Deal found 9/29![American Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2210:20 am -
1 stop6h 15m
Fri 12/255:45 pm -
2 stops16h 03m
Deal found 9/30![United Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/236:50 pm -
1 stop17h 14m
Sat 2/63:34 pm -
1 stop7h 54m
Deal found 10/3![American Airlines logo]()
$418
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/167:30 am -
2 stops12h 20m
Thu 1/2112:48 pm -
2 stops9h 35m
Deal found 10/2![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:52 pm -
1 stop16h 34m
Wed 12/168:15 am -
2 stops13h 44m
Deal found 9/29![American Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:58 pm -
2 stops22h 32m
Thu 10/294:45 pm -
2 stops30h 01m
Deal found 9/30![United Airlines logo]()
$552
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:44 pm -
2 stops17h 27m
Tue 12/2912:42 pm -
2 stops10h 24m
Deal found 10/4![American Airlines logo]()
$499
Last-minute flights from Buffalo to Cayman IslandsDiscover last-minute flight deals from Buffalo to Cayman Islands. Data last updated October 4, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Cayman Islands. Data last updated October 4, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:58 pm -
2 stops22h 32m
Thu 10/294:45 pm -
2 stops30h 01m
Deal found 9/29![United Airlines logo]()
$552
This CheapTicketsDeal deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapTicketsDeal is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:10 am -
1 stop7h 30m
Sat 11/282:25 pm -
1 stop10h 35m
Deal found 9/30![JetBlue logo]()
$731
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:56 am -
1 stop6h 09m
Sat 11/288:15 am -
2 stops15h 33m
Deal found 9/30![American Airlines logo]()
$923
This Booking.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:54 pm -
3 stops24h 56m
Sat 11/2811:25 am -
2 stops9h 05m
Deal found 9/30![Multiple Airlines logo]()
$1,374
This deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:00 am -
1 stop8h 00m
Sun 11/293:10 pm -
1 stop7h 23m
Deal found 9/30![JetBlue logo]()
$5,000
Find flight deals from Buffalo to Cayman Islands
Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated October 4, 2026.
Round-trip from | $407 (Delta) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 4, 2026.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Sun 12/13
7:36 pm-11:26 am
1 stop15h 50m
George Town Owen Roberts Intl
Thu 12/17
1:06 pm-11:06 pm
1 stop10h 00m
$417
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Sat 1/23
6:50 pm-12:04 pm
1 stop17h 14m
George Town Owen Roberts Intl
Sat 2/6
3:34 pm-11:28 pm
1 stop7h 54m
$418
Quickest round-trip
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Sat 1/16
7:30 am-7:50 pm
2 stops12h 20m
George Town Owen Roberts Intl
Thu 1/21
12:48 pm-10:23 pm
2 stops9h 35m
$422
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Sat 12/12
6:52 pm-11:26 am
1 stop16h 34m
George Town Owen Roberts Intl
Wed 12/16
8:15 am-9:59 pm
2 stops13h 44m
$422
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Thu 12/24
6:44 pm-12:11 pm
2 stops17h 27m
George Town Owen Roberts Intl
Tue 12/29
12:42 pm-11:06 pm
2 stops10h 24m
$499
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Tue 12/22
10:20 am-4:35 pm
1 stop6h 15m
George Town Owen Roberts Intl
Fri 12/25
5:45 pm-9:48 am
2 stops16h 03m
$537
BuffaloGeorge Town
BUF Buffalo - GCM George Town Owen Roberts Intl
BUFGCM
Buffalo
Tue 10/27
5:58 pm-3:30 pm
2 stops22h 32m
George Town Owen Roberts Intl
Thu 10/29
4:45 pm-11:46 pm
2 stops30h 01m
$552
Sorted by cheapest first
Best time to book a flight from Buffalo to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
BUF-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to the Cayman Islands
BUF-KY0
BUF-GCM
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Cayman Islands
Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated October 4, 2026.
Peruse reviews from past customers who have flown with American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.0
Entertainment
6.8
Crew
7.9
Food
6.4
Boarding
7.4
Comfort
7.2
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Overall
7.0
Entertainment
6.8
Crew
7.9
Food
6.4
Boarding
7.4
Comfort
7.2
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to Cayman Islands
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Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
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Buffalo and Cayman Islands flights
Browse other Buffalo and Cayman Islands flight options. Last updated on October 4, 2026.
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Top airline flying from Buffalo to Cayman Islands
Discover the top airline that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$325 | Average$555 | FlexibilityNo cancel fee | On-time71% |