$246+ Cheap flights from Missoula to Buffalo (MSO - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — BUF
May 2 — May 91
Round-trip
1 adult, Economy
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Find cheap flights from Missoula to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missoula to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missoula to BuffaloExplore the most affordable flight options available from Missoula to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.
Explore the most affordable flight options available from Missoula to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/161:08 pm
MSO
- BUF
1 stop6h 28m
American Airlines
Sat 5/236:00 am
BUF
- MSO
1 stop8h 49m
American Airlines
Deal found 4/1![American Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:40 pm
MSO
- BUF
1 stop5h 51m
United Airlines
Sat 10/247:00 am
BUF
- MSO
1 stop6h 34m
United Airlines
Deal found 3/29![United Airlines logo]()
$469
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:25 am
MSO
- BUF
2 stops14h 33m
United Airlines
Sun 8/97:00 am
BUF
- MSO
1 stop6h 32m
United Airlines
Deal found 3/31![United Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:25 am
MSO
- BUF
2 stops14h 33m
United Airlines
Tue 7/147:00 am
BUF
- MSO
1 stop6h 32m
United Airlines
Deal found 4/1![United Airlines logo]()
$586
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:18 pm
MSO
- BUF
1 stop7h 15m
American Airlines
Sun 1/36:00 am
BUF
- MSO
1 stop8h 48m
American Airlines
Deal found 3/30![American Airlines logo]()
$598
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/181:19 pm
MSO
- BUF
1 stop8h 55m
American Airlines
Mon 6/226:00 am
BUF
- MSO
1 stop8h 49m
American Airlines
Deal found 4/1![American Airlines logo]()
$604
Best flights from Missoula to BuffaloDiscover carefully curated flight deals from Missoula to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2026.
Discover carefully curated flight deals from Missoula to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2026.
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:45 am
MSO
- BUF
2 stops12h 51m
American Airlines
Sat 5/238:00 am
BUF
- MSO
1 stop6h 49m
American Airlines
Deal found 4/1![American Airlines logo]()
$455
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:25 am
MSO
- BUF
2 stops14h 33m
United Airlines
Sun 8/97:00 am
BUF
- MSO
1 stop6h 32m
United Airlines
Deal found 3/31![United Airlines logo]()
$578
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:05 pm
MSO
- BUF
2 stops15h 08m
Delta
Sat 5/236:25 am
BUF
- MSO
2 stops10h 15m
Delta
Deal found 4/1![Delta logo]()
$679
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:25 am
MSO
- BUF
2 stops14h 33m
United Airlines
Tue 7/147:00 am
BUF
- MSO
1 stop6h 32m
United Airlines
Deal found 4/1![United Airlines logo]()
$586
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:45 am
MSO
- BUF
1 stop7h 09m
American Airlines
Sun 8/96:30 am
BUF
- MSO
1 stop7h 46m
American Airlines
Deal found 3/29![American Airlines logo]()
$663
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/112:21 pm
MSO
- BUF
1 stop6h 37m
United Airlines
Tue 7/147:00 am
BUF
- MSO
1 stop6h 32m
United Airlines
Deal found 4/1![United Airlines logo]()
$614
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:45 am
MSO
- BUF
2 stops13h 45m
American Airlines
Tue 7/146:00 am
BUF
- MSO
2 stops12h 11m
American Airlines
Deal found 4/1![American Airlines logo]()
$664
Last-minute flights from Missoula to BuffaloDiscover last-minute flight deals from Missoula to Buffalo. Data last updated April 2, 2026 and is based on user searches.
Discover last-minute flight deals from Missoula to Buffalo. Data last updated April 2, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/161:08 pm
MSO
- BUF
1 stop6h 28m
American Airlines
Sat 5/236:00 am
BUF
- MSO
1 stop8h 49m
American Airlines
Deal found 4/1![American Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:05 pm
MSO
- BUF
2 stops15h 08m
Delta
Sat 5/236:25 am
BUF
- MSO
2 stops10h 15m
Delta
Deal found 4/1![Delta logo]()
$679
One-way flights from Missoula to BuffaloSearch for one-way flight options from Missoula to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 2, 2026.
Search for one-way flight options from Missoula to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:46 pm
MSO
- BUF
3 stops45h 08m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$246
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:34 pm
MSO
- BUF
1 stop6h 29m
United Airlines
Deal found 3/30![United Airlines logo]()
$311
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/1412:34 pm
MSO
- BUF
1 stop6h 29m
United Airlines
Deal found 3/31![United Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:45 am
MSO
- BUF
2 stops12h 38m
American Airlines
Deal found 4/1![American Airlines logo]()
$453
Find flight deals from Missoula to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Missoula (MSO) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $395 (American Airlines) |
One-way from | $246 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Missoula to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from Missoula to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MissoulaBuffalo
MSO - BUF
MSOBUF
Missoula Johnson-Bell Field
Sat 5/16
6:45 am-9:36 pm
2 stops12h 51m
Buffalo
Sat 5/23
8:00 am-12:49 pm
1 stop6h 49m
$455
MissoulaBuffalo
MSO - BUF
MSOBUF
Missoula Johnson-Bell Field
Sat 8/1
6:25 am-10:58 pm
2 stops14h 33m
Buffalo
Sun 8/9
7:00 am-11:32 am
1 stop6h 32m
$578
MissoulaBuffalo
MSO - BUF
MSOBUF
Missoula Johnson-Bell Field
Thu 7/9
6:25 am-10:58 pm
2 stops14h 33m
Buffalo
Tue 7/14
7:00 am-11:32 am
1 stop6h 32m
$586
Quickest round-trip
MissoulaBuffalo
MSO - BUF
MSOBUF
Missoula Johnson-Bell Field
Sat 7/11
2:21 pm-10:58 pm
1 stop6h 37m
Buffalo
Tue 7/14
7:00 am-11:32 am
1 stop6h 32m
$614
MissoulaBuffalo
MSO - BUF
MSOBUF
Missoula Johnson-Bell Field
Sat 8/1
6:45 am-3:54 pm
1 stop7h 09m
Buffalo
Sun 8/9
6:30 am-12:16 pm
1 stop7h 46m
$663
MissoulaBuffalo
MSO - BUF
MSOBUF
Missoula Johnson-Bell Field
Sat 7/11
6:45 am-10:30 pm
2 stops13h 45m
Buffalo
Tue 7/14
6:00 am-4:11 pm
2 stops12h 11m
$664
MissoulaBuffalo
MSO - BUF
MSOBUF
Missoula Johnson-Bell Field
Sat 5/16
6:05 pm-11:13 am
2 stops15h 08m
Buffalo
Sat 5/23
6:25 am-2:40 pm
2 stops10h 15m
$679
Cheapest one-way
Quickest one-way
MissoulaBuffalo
MSO - BUF
MSOBUF
Missoula Johnson-Bell Field
Sun 6/14
12:34 pm-9:03 pm
1 stop6h 29m
$361
MissoulaBuffalo
MSO - BUF
MSOBUF
Missoula Johnson-Bell Field
Sun 6/14
6:45 am-9:23 pm
2 stops12h 38m
$453
MissoulaBuffalo
MSO - BUF
MSOBUF
Missoula Johnson-Bell Field
Mon 6/1
12:34 pm-9:03 pm
1 stop6h 29m
$929
Sorted by cheapest first
Compare providers for flights from Missoula to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Missoula to Buffalo in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Missoula-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Missoula-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Missoula-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Missoula-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Missoula-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Missoula to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missoula with our price prediction graph.
MSO-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated April 2, 2026.
Read through reviews of airlines operating flights from Missoula to Buffalo, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Boarding
7.7
Overall
7.4
Food
6.6
Comfort
7.3
Crew
8.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Entertainment
7.1
Boarding
7.7
Overall
7.4
Food
6.6
Comfort
7.3
Crew
8.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Entertainment
7.1
Boarding
7.7
Overall
7.4
Food
6.6
Comfort
7.3
Crew
8.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Related info for your journey
Find useful and relevant information for your journey from Missoula to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 2, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
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Missoula and Buffalo flights
Browse other Missoula and Buffalo flight options. Last updated on April 2, 2026.
Other flights from Missoula
Browse through other flights departing from Missoula. Flights are based on user searches made on Cheapflights and were last updated on April 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Missoula to Buffalo
Discover the top 2 airlines that operate flights from Missoula to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$474 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$288 | Average$508 | FlexibilityNo cancel fee | On-time69% |