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$373+ Cheap flights from Des Moines (DSM) to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BRU
ago 4 — ago 111
seg 8/4
seg 8/11
1 adult, Economy
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Cheap flight deals from Des Moines to Brussels

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julho 30, 2025.

Round-trip from

$660
(FlightHub)

One-way from

$373
(Kiwi.com)
From Des Moines to Brussels
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One-way flight from Des Moines to Brussels
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Find flight deals from Des Moines to Brussels

Cheapest flights from Des Moines to Brussels
Explore the most affordable flight options available from Des Moines to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julho 30, 2025.

This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 10/1710:52 amDSM - BRU
2 stops39h 48mScandinavian Airlines
dom 10/263:10 pmBRU - DSM
2 stops37h 33mScandinavian Airlines
Deal found 7/29$660
This Ticket deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 9/138:00 amDSM - BRU
2 stops17h 05mAir Canada
sáb 9/2010:00 amBRU - DSM
2 stops14h 14mAir Canada
Deal found 7/30$746
This British Airways deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 9/116:09 pmDSM - BRU
2 stops17h 41mBritish Airways
qui 9/1810:50 amBRU - DSM
2 stops16h 31mBritish Airways
Deal found 7/30$752
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 9/118:00 amDSM - BRU
1 stop18h 00mUnited Airlines
qui 9/1810:00 amBRU - DSM
2 stops35h 10mUnited Airlines
Deal found 7/30$753
This Booking.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 9/1311:35 amDSM - BRU
2 stops37h 30mMultiple Airlines
sáb 9/2012:45 pmBRU - DSM
2 stops40h 00mMultiple Airlines
Deal found 7/30$803
This Flysmarter deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 9/1311:35 amDSM - BRU
1 stop14h 25mLufthansa
sáb 9/2010:15 amBRU - DSM
1 stop13h 59mLufthansa
Deal found 7/30$832
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 10/171:48 pmDSM - BRU
2 stops14h 37mAmerican Airlines
dom 10/2611:20 amBRU - DSM
3 stops18h 03mAmerican Airlines
Deal found 7/29$1,056

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julho 30, 2025.
Use the filters below to find and compare flights from Des Moines to Brussels that are best for you.

Fly from

Des Moines

Fly to

Brussels

Route

Depart

Return

Price

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

sex 10/17

10:52 am-9:40 am

2 stops39h 48m

Brussels Bruxelles-National

dom 10/26

3:10 pm-10:43 pm

2 stops37h 33m

$660

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

sáb 9/13

8:00 am-8:05 am

2 stops17h 05m

Brussels Bruxelles-National

sáb 9/20

10:00 am-5:14 pm

2 stops14h 14m

$746

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

qui 9/11

6:09 pm-6:50 pm

2 stops17h 41m

Brussels Bruxelles-National

qui 9/18

10:50 am-8:21 pm

2 stops16h 31m

$752

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

qui 9/11

8:00 am-9:00 am

1 stop18h 00m

Brussels Bruxelles-National

qui 9/18

10:00 am-2:10 pm

2 stops35h 10m

$753

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

sáb 9/13

3:25 pm-8:05 am

2 stops33h 40m

Brussels Bruxelles-National

sáb 9/20

12:45 pm-9:45 pm

2 stops40h 00m

$803

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

sáb 9/13

11:35 am-9:00 am

1 stop14h 25m

Brussels Bruxelles-National

sáb 9/20

10:15 am-5:14 pm

1 stop13h 59m

$832

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

sex 10/17

1:48 pm-11:25 am

2 stops14h 37m

Brussels Bruxelles-National

dom 10/26

11:20 am-11:23 pm

3 stops18h 03m

$1,056

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

qua 9/3

10:14 am-4:55 pm

3 stops47h 41m

$373

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

qua 9/3

4:19 pm-8:25 pm

2 stops21h 06m

$473

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

qua 9/3

1:10 pm-9:00 am

1 stop12h 50m

$565

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 11 results
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Best time to book a flight from Des Moines to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Brussels
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated julho 30, 2025.
See what other customers who have flown with United Airlines, Scandinavian Airlines, and American Airlines from Des Moines to Brussels have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,896 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
United Airlines
7.4
Good
8,896 reviews
United Airlines
7.4
Good
8,896 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
Scandinavian Airlines
7.3
Good
1,453 reviews
United Airlines
7.4
Good
8,896 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,896 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
Air Canada
7.1
Good
9,837 reviews
United Airlines
7.4
Good
8,896 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
Lufthansa
6.8
Okay
7,269 reviews
United Airlines
7.4
Good
8,896 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Brussels?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Brussels. 1 airline have flights from Des Moines to Brussels on a regular basis. Booking flights from Des Moines to Brussels should not be difficult; the airport handles an average of 0 outbound flights to Brussels per day.

  • What are the cheapest airlines flying from Des Moines to Brussels round-trip?

    According to our current data, Scandinavian Airlines ($660), Air Canada ($746), and British Airways ($752) offers the cheapest pricing from Des Moines to Brussels.

  • What are the cheapest airlines to fly from Des Moines to Brussels one-way?

    The cheapest airlines for a one-way flight from Des Moines to Brussels are British Airways ($473), Lufthansa ($565), and United Airlines ($608).

  • Can I find deals for flights from Des Moines to Brussels that include hotel bookings?

    Yes. In addition to deals on Des Moines to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Brussels.

  • Can I find deals for business class flights from Des Moines to Brussels?

    Yes. Cheapflights offers flight deals from Des Moines to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Brussels?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Brussels (average of $614). Flying from Des Moines to Brussels in June is currently the most expensive (average of $1,081). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Bruxelles-National flights
Omaha to Bruxelles-National flights

Top airline flying from Des Moines to Brussels

Discover the top airline that operate flights from Des Moines to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julho 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$794Average$1,240FlexibilityNo cancel feeOn-time69%

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