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$266+ Cheap flights from Des Moines (DSM) to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BRU
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Des Moines to Brussels

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$651
(United Airlines)

One-way from

$266
(Mytrip)
From Des Moines to Brussels
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One-way flight from Des Moines to Brussels
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Find flight deals from Des Moines to Brussels

Cheapest flights from Des Moines to Brussels
Explore the most affordable flight options available from Des Moines to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/153:25 pmDSM - BRU
1 stop10h 35mUnited Airlines
Tue 10/2110:00 amBRU - DSM
2 stops33h 19mUnited Airlines
Deal found 6/11$651
This Air Canada deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:15 amDSM - BRU
3 stops16h 50mAir Canada
Tue 10/2110:00 amBRU - DSM
3 stops18h 50mAir Canada
Deal found 6/11$687
This Gotogate deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/166:00 amDSM - BRU
2 stops19h 00mMultiple Airlines
Wed 7/232:25 pmBRU - DSM
2 stops15h 35mMultiple Airlines
Deal found 6/11$883
This Flighttix deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1611:25 amDSM - BRU
1 stop14h 35mLufthansa
Wed 7/2310:15 amBRU - DSM
1 stop19h 45mLufthansa
Deal found 6/10$893
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/235:30 amDSM - BRU
2 stops20h 10mDelta
Wed 7/308:00 amBRU - DSM
2 stops19h 57mDelta
Deal found 6/12$898
This Billigflug deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/236:40 pmDSM - BRU
1 stop31h 00mAir France
Wed 7/3010:45 amBRU - DSM
1 stop18h 48mAir France
Deal found 6/11$1,016
This Richmond deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Richmond is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2611:59 amDSM - BRU
1 stop13h 41mKLM
Sat 8/26:10 amBRU - DSM
2 stops21h 47mKLM
Deal found 6/11$1,098
This Iberia deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/710:03 amDSM - BRU
2 stops25h 52mIberia
Sat 7/127:05 amBRU - DSM
2 stops20h 30mIberia
Deal found 6/10$2,723

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Des Moines to Brussels that are best for you.

Fly from

Des Moines

Fly to

Brussels

Route

Depart

Return

Price

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 10/15

3:25 pm-9:00 am

1 stop10h 35m

Brussels Bruxelles-National

Tue 10/21

10:00 am-12:19 pm

2 stops33h 19m

$651

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 10/15

8:15 am-8:05 am

3 stops16h 50m

Brussels Bruxelles-National

Tue 10/21

10:00 am-9:50 pm

3 stops18h 50m

$687

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 7/16

6:00 am-8:00 am

2 stops19h 00m

Brussels Bruxelles-National

Wed 7/23

2:25 pm-11:00 pm

2 stops15h 35m

$883

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 7/16

11:25 am-9:00 am

1 stop14h 35m

Brussels Bruxelles-National

Wed 7/23

10:15 am-11:00 pm

1 stop19h 45m

$893

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 7/23

5:30 am-8:40 am

2 stops20h 10m

Brussels Bruxelles-National

Wed 7/30

8:00 am-8:57 pm

2 stops19h 57m

$898

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 7/23

6:40 pm-8:40 am

1 stop31h 00m

Brussels Bruxelles-National

Wed 7/30

10:45 am-10:33 pm

1 stop18h 48m

$1,016

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sat 7/26

11:59 am-8:40 am

1 stop13h 41m

Brussels Bruxelles-National

Sat 8/2

6:10 am-8:57 pm

2 stops21h 47m

$1,098

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Mon 7/7

10:03 am-6:55 pm

2 stops25h 52m

Brussels Bruxelles-National

Sat 7/12

7:05 am-8:35 pm

2 stops20h 30m

$2,723

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Fri 7/25

6:00 am-12:50 pm

2 stops23h 50m

$266

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sat 7/26

6:50 pm-8:00 am

2 stops30h 10m

$458

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 13 results
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Best time to book a flight from Des Moines to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Brussels

Rainfall in Brussels by month

Plan your trip to Brussels by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Brussels ranges from 1.6 - 3.1 inches per month. January is typically the wettest month, when rainfall can reach 3.1 in. August is typically the driest time to visit Brussels when rainfall is around 1.6 in.

Temperature in Brussels by month

Plan your trip to Brussels by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Brussels, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,358 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air France
7.5
Good
1,463 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air Canada
7.1
Good
9,531 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Brussels?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Brussels. 1 airline have flights from Des Moines to Brussels on a regular basis. Booking flights from Des Moines to Brussels should not be difficult; the airport handles an average of 0 outbound flights to Brussels per day.

  • What are the cheapest airlines flying from Des Moines to Brussels round-trip?

    According to our current data, United Airlines ($651), Air Canada ($687), and Lufthansa ($893) offers the cheapest pricing from Des Moines to Brussels.

  • What are the cheapest airlines to fly from Des Moines to Brussels one-way?

    The cheapest airlines for a one-way flight from Des Moines to Brussels are Air Canada ($458), United Airlines ($480), and Delta ($495).

  • Can I find deals for flights from Des Moines to Brussels that include hotel bookings?

    Yes. In addition to deals on Des Moines to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Brussels.

  • Can I find deals for business class flights from Des Moines to Brussels?

    Yes. Cheapflights offers flight deals from Des Moines to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Brussels?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Brussels (average of $614). Flying from Des Moines to Brussels in June is currently the most expensive (average of $1,096). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Bruxelles-National flights
Omaha to Bruxelles-National flights

Top airline flying from Des Moines to Brussels

Discover the top airline that operate flights from Des Moines to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$794Average$1,243FlexibilityNo cancel feeOn-time69%

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