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Biloxi

$135+ Cheap flights from Knoxville (TYS) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/10. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Knoxville to Biloxi

Keep the following information in mind while searching for Knoxville to Biloxi flight deals. Data was last updated junio 12, 2025.

Round-trip from

$229
(American Airlines)

One-way from

$135
(Delta)

Popular in

July

Cheapest in

June

Average price

$233
From Knoxville McGhee Tyson to Biloxi
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One-way flight from Knoxville McGhee Tyson to Biloxi
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Highest demand for flights based on searches. 7% potential increase in price ($25 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Knoxville to Biloxi

Cheapest flights from Knoxville to Biloxi
Explore the most affordable flight options available from Knoxville to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/207:35 pmTYS - GPT
1 stop3h 49mAmerican Airlines
lun. 8/251:48 pmGPT - TYS
1 stop4h 06mAmerican Airlines
Deal found 6/11$229
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/105:30 amTYS - GPT
1 stop4h 24mDelta
jue. 7/176:00 pmGPT - TYS
1 stop4h 59mDelta
Deal found 6/12$279
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/253:10 pmTYS - GPT
1 stop22h 05mMultiple Airlines
dom. 6/2912:55 pmGPT - TYS
1 stop20h 14mMultiple Airlines
Deal found 6/10$380
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/209:30 amTYS - GPT
1 stop4h 57mUnited Airlines
lun. 8/255:15 pmGPT - TYS
2 stops19h 10mUnited Airlines
Deal found 6/10$408

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Knoxville to Biloxi that are best for you.

Fly from

Knoxville

Fly to

Biloxi

Route

Depart

Return

Price

KnoxvilleGulfport

TYS - GPT

TYSGPT

Knoxville McGhee Tyson

mié. 8/20

1:29 pm-4:17 pm

1 stop3h 48m

Gulfport Biloxi Regional

lun. 8/25

1:48 pm-6:54 pm

1 stop4h 06m

$229

KnoxvilleGulfport

TYS - GPT

TYSGPT

Knoxville McGhee Tyson

jue. 7/10

5:30 am-8:54 am

1 stop4h 24m

Gulfport Biloxi Regional

jue. 7/17

6:00 pm-11:59 pm

1 stop4h 59m

$279

KnoxvilleGulfport

TYS - GPT

TYSGPT

Knoxville McGhee Tyson

mié. 6/25

3:10 pm-12:15 pm

1 stop22h 05m

Gulfport Biloxi Regional

dom. 6/29

12:55 pm-10:09 am

1 stop20h 14m

$380

KnoxvilleGulfport

TYS - GPT

TYSGPT

Knoxville McGhee Tyson

mié. 8/20

9:30 am-1:27 pm

1 stop4h 57m

Gulfport Biloxi Regional

lun. 8/25

5:15 pm-1:25 pm

2 stops19h 10m

$408

KnoxvilleGulfport

TYS - GPT

TYSGPT

Knoxville McGhee Tyson

jue. 7/10

5:30 am-8:54 am

1 stop4h 24m

$135

KnoxvilleGulfport

TYS - GPT

TYSGPT

Knoxville McGhee Tyson

jue. 7/10

3:11 pm-7:45 am

2 stops17h 34m

$283

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Best time to book a flight from Knoxville to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Biloxi

What is the cheapest month to book a flight from Knoxville to Biloxi?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Biloxi (average of $256). Flying from Knoxville to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to B1L?

Find hourly flight availability from Knoxville to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from Knoxville to Biloxi, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Knoxville to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Biloxi. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to Biloxi flight should consider departing on Thursday mornings when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Biloxi by month

Plan your trip to Biloxi by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Biloxi ranges from 3.6 - 7.2 inches per month. July is typically the wettest month, when rainfall can reach 7.2 in. October is typically the driest time to visit Biloxi when rainfall is around 3.6 in.

Temperature in Biloxi by month

Plan your trip to Biloxi by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Biloxi, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 50.0 F).

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated junio 12, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines and American Airlines from Knoxville to Biloxi to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Overall

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Overall

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Overall

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Overall

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Biloxi?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Biloxi. You should not have trouble finding flights to Biloxi from McGhee Tyson; the airport handles an average of 0 outbound flights to Biloxi per day. You should also have plenty of airline options to choose from since 4 airlines have flights from the Knoxville airport to Biloxi. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • Can I find deals for flights from Knoxville to Biloxi that include hotel bookings?

    Yes. In addition to deals on Knoxville to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Biloxi.

  • Can I find deals for business class flights from Knoxville to Biloxi?

    Yes. Cheapflights offers flight deals from Knoxville to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Biloxi?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Biloxi (average of $256). Flying from Knoxville to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Biloxi

Discover the top 4 airlines that operate flights from Knoxville to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$71Average$88FlexibilityNo cancel feeOn-time88%
DeltaCheapest$218Average$407FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$435FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$253Average$408FlexibilityNo cancel feeOn-time69%

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