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Antofagasta

$673+ Cheap flights from O'Hare Intl (ORD) to Antofagasta (ANF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — ANF
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Cheap flight deals from O'Hare Intl to Antofagasta

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Antofagasta (ANF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$930
(Mytrip)

One-way from

$673
(LATAM Airlines)
Provider with most accurate pricing for Chicago O'Hare Intl-Antofagasta Cerro Moreno flight deals.
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Provider most trusted by Cheapflights users for Chicago O'Hare Intl-Antofagasta Cerro Moreno flights.
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From Chicago O'Hare Intl to Antofagasta Cerro Moreno
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One-way flight from Chicago O'Hare Intl to Antofagasta Cerro Moreno
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Find flight deals from O'Hare Intl to Antofagasta

Cheapest flights from O'Hare Intl to Antofagasta
Explore the most affordable flight options available from O'Hare Intl to Antofagasta. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This Mytrip deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:26 pmORD - ANF
3 stops25h 10mMultiple Airlines
Tue 12/169:42 pmANF - ORD
2 stops25h 38mMultiple Airlines
Deal found 11/26$930
This Delta deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:45 amORD - ANF
2 stops26h 32mDelta
Wed 12/108:40 pmANF - ORD
2 stops45h 40mDelta
Deal found 11/24$995
This LATAM Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/610:36 amORD - ANF
2 stops22h 41mLATAM Airlines
Wed 12/108:07 pmANF - ORD
2 stops19h 36mLATAM Airlines
Deal found 11/23$1,385

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Antofagasta that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Antofagasta that are best for you.

Fly from

O'Hare Intl

Fly to

Antofagasta

Route

Depart

Return

Price

ChicagoAntofagasta

ORD - ANF

ORDANF

Chicago O'Hare Intl

Fri 12/12

3:26 pm-7:36 pm

3 stops25h 10m

Antofagasta Cerro Moreno

Tue 12/16

9:42 pm-8:20 pm

2 stops25h 38m

$930

ChicagoAntofagasta

ORD - ANF

ORDANF

Chicago O'Hare Intl

Sat 12/6

6:45 am-12:17 pm

2 stops26h 32m

Antofagasta Cerro Moreno

Wed 12/10

8:40 pm-3:20 pm

2 stops45h 40m

$995

ChicagoAntofagasta

ORD - ANF

ORDANF

Chicago O'Hare Intl

Sat 12/6

10:36 am-12:17 pm

2 stops22h 41m

Antofagasta Cerro Moreno

Wed 12/10

8:07 pm-12:43 pm

2 stops19h 36m

$1,385

ChicagoAntofagasta

ORD - ANF

ORDANF

Chicago O'Hare Intl

Mon 12/15

5:30 am-4:30 am

2 stops20h 00m

$673

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/24

  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Antofagasta flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Antofagasta flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Antofagasta flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Antofagasta flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Antofagasta flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Antofagasta

Have a flexible travel schedule? Discover the best time to fly to Antofagasta from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Antofagasta. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Antofagasta from Chicago O'Hare Intl?

    Located just 14.7 mi from the city center, Antofagasta Cerro Moreno is the airport most travelers will use when flying to Antofagasta from Chicago O'Hare Intl. Booking flights from Chicago O'Hare Intl to Cerro Moreno (ANF) should be relatively easy as there are 0 daily inbound flights from Chicago O'Hare Intl from 0 different airlines.

  • How long is the flight from Chicago O'Hare Intl Airport to Antofagasta?

    Airlines like Delta and LATAM Airlines fly from Chicago O'Hare Intl Airport to Antofagasta in about 22h 41m. The time it takes to get you to your destination can typically vary by up to 3h 51m. Chicago O'Hare Intl Airport and Antofagasta are separated by a distance of 4653 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from O'Hare Intl to Antofagasta that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Antofagasta flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Antofagasta?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Antofagasta.

  • Can I find deals for business class flights from O'Hare Intl to Antofagasta?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Antofagasta by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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