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Antofagasta

$330+ Cheap flights from O'Hare Intl (ORD) to Antofagasta (ANF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — ANF
Jan 29 — Feb 51
Thu 1/29
Thu 2/5
1 adult, Economy
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Cheap flight deals from O'Hare Intl to Antofagasta

Best flights from O'Hare Intl to Antofagasta
Discover carefully curated flight deals from O'Hare Intl to Antofagasta that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 30, 2025.

This LATAM Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:48 amORD - ANF
2 stops33h 18mLATAM Airlines
Mon 3/94:01 pmANF - ORD
2 stops23h 37mLATAM Airlines
Deal found 12/27$853

Find flight deals from O'Hare Intl to Antofagasta

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Antofagasta (ANF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$853
(LATAM Airlines)

One-way from

$330
(Kiwi.com)
Provider with most accurate pricing for Chicago O'Hare Intl-Antofagasta Cerro Moreno flight deals.
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Provider most trusted by Cheapflights users for Chicago O'Hare Intl-Antofagasta Cerro Moreno flights.
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From Chicago O'Hare Intl to Antofagasta Cerro Moreno
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One-way flight from Chicago O'Hare Intl to Antofagasta Cerro Moreno
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Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Antofagasta that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Antofagasta that are best for you.

Fly from

O'Hare Intl

Fly to

Antofagasta

Route

Depart

Return

Price

ChicagoAntofagasta

ORD - ANF

ORDANF

Chicago O'Hare Intl

Thu 3/5

9:48 am-10:06 pm

2 stops33h 18m

Antofagasta Cerro Moreno

Mon 3/9

4:01 pm-1:38 pm

2 stops23h 37m

$853

ChicagoAntofagasta

ORD - ANF

ORDANF

Chicago O'Hare Intl

Wed 1/21

9:23 am-8:20 am

3 stops43h 57m

$330

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Antofagasta flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Antofagasta flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Antofagasta flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Antofagasta flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Antofagasta flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Antofagasta

Have a flexible travel schedule? Discover the best time to fly to Antofagasta from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Antofagasta. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Antofagasta from Chicago O'Hare Intl?

    Located just 14.7 mi from the city center, Antofagasta Cerro Moreno is the airport most travelers will use when flying to Antofagasta from Chicago O'Hare Intl. Booking flights from Chicago O'Hare Intl to Cerro Moreno (ANF) should be relatively easy as there are 0 daily inbound flights from Chicago O'Hare Intl from 0 different airlines.

  • How long is the flight from Chicago O'Hare Intl Airport to Antofagasta?

    Airlines like LATAM Airlines fly from Chicago O'Hare Intl Airport to Antofagasta in about 33h 18m. The time it takes to get you to your destination can typically vary by up to . Chicago O'Hare Intl Airport and Antofagasta are separated by a distance of 4653 mi.

  • Can I find deals for flights from O'Hare Intl to Antofagasta that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Antofagasta flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Antofagasta?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Antofagasta.

  • Can I find deals for business class flights from O'Hare Intl to Antofagasta?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Antofagasta by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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