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Amarillo

$189+ Cheap flights from South Carolina to Amarillo (AMA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/4. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — AMA
Mar 13 — Mar 201
Fri 3/13
Fri 3/20
1 adult, Economy
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Cheap flight deals from South Carolina to Amarillo

Cheapest flights from South Carolina to Amarillo
Explore the most affordable flight options available from South Carolina to Amarillo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.

This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
GSP
-
AMA
1 stop5h 21m
United Airlines
Tue 6/23:15 pm
AMA
-
GSP
1 stop5h 56m
United Airlines
Deal found 2/10$407
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:06 pm
GSP
-
AMA
2 stops8h 53m
American Airlines
Tue 6/24:17 pm
AMA
-
GSP
1 stop5h 40m
American Airlines
Deal found 2/10$412
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:50 pm
GSP
-
AMA
2 stops10h 20m
Southwest
Tue 6/27:00 am
AMA
-
GSP
2 stops12h 00m
Southwest
Deal found 2/10$446
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:53 pm
GSP
-
AMA
1 stop5h 06m
American Airlines
Mon 6/296:00 am
AMA
-
GSP
1 stop6h 08m
American Airlines
Deal found 2/9$447
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:20 am
CHS
-
AMA
2 stops7h 10m
Southwest
Fri 3/2012:10 pm
AMA
-
CHS
1 stop7h 05m
Southwest
Deal found 2/11$492
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:01 am
GSP
-
AMA
1 stop6h 59m
American Airlines
Mon 3/210:20 am
AMA
-
GSP
1 stop4h 16m
American Airlines
Deal found 2/11$507
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/137:03 am
CHS
-
AMA
1 stop5h 57m
American Airlines
Fri 3/206:00 am
AMA
-
CHS
1 stop14h 35m
American Airlines
Deal found 2/11$521
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/264:25 pm
GSP
-
AMA
2 stops7h 45m
Southwest
Mon 3/210:00 am
AMA
-
GSP
2 stops9h 20m
Southwest
Deal found 2/11$523
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:45 pm
CHS
-
AMA
1 stop5h 21m
American Airlines
Sun 3/112:30 pm
AMA
-
CHS
1 stop5h 01m
American Airlines
Deal found 2/10$547
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:40 am
CHS
-
AMA
2 stops10h 50m
Southwest
Sun 3/12:30 pm
AMA
-
CHS
1 stop4h 40m
Southwest
Deal found 2/10$552
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2511:18 am
GSP
-
AMA
2 stops12h 12m
United Airlines
Mon 6/293:15 pm
AMA
-
GSP
1 stop5h 56m
United Airlines
Deal found 2/11$598
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:00 am
CHS
-
AMA
2 stops11h 56m
United Airlines
Mon 3/29:05 am
AMA
-
CHS
2 stops11h 22m
United Airlines
Deal found 2/11$764

Find flight deals from South Carolina to Amarillo

Keep the following information in mind while searching for South Carolina to Amarillo flight deals. Data was last updated February 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$407
(United Airlines)

One-way from

$189
(American Airlines)
Provider with most accurate pricing for Myrtle Beach Intl-Amarillo flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Amarillo flights.
Search Deals
From South Carolina to Amarillo
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One-way flight from South Carolina to Amarillo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Amarillo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from South Carolina to Amarillo that are best for you.

Fly from

South Carolina

Fly to

Amarillo

Route

Depart

Return

Price

GreenvilleAmarillo

GSP - AMA

GSPAMA

Greenville

Wed 5/27

7:00 am-11:21 am

1 stop5h 21m

Amarillo

Tue 6/2

3:15 pm-10:11 pm

1 stop5h 56m

$407

GreenvilleAmarillo

GSP - AMA

GSPAMA

Greenville

Wed 5/27

4:06 pm-11:59 pm

2 stops8h 53m

Amarillo

Tue 6/2

4:17 pm-10:57 pm

1 stop5h 40m

$412

GreenvilleAmarillo

GSP - AMA

GSPAMA

Greenville

Wed 5/27

12:50 pm-10:10 pm

2 stops10h 20m

Amarillo

Tue 6/2

7:00 am-8:00 pm

2 stops12h 00m

$446

GreenvilleAmarillo

GSP - AMA

GSPAMA

Greenville

Thu 6/25

6:29 am-12:47 pm

1 stop7h 18m

Amarillo

Mon 6/29

6:00 am-1:08 pm

1 stop6h 08m

$447

GreenvilleAmarillo

GSP - AMA

GSPAMA

Greenville

Thu 2/26

6:01 am-12:00 pm

1 stop6h 59m

Amarillo

Mon 3/2

10:20 am-3:36 pm

1 stop4h 16m

$507

GreenvilleAmarillo

GSP - AMA

GSPAMA

Greenville

Thu 2/26

4:25 pm-11:10 pm

2 stops7h 45m

Amarillo

Mon 3/2

10:00 am-8:20 pm

2 stops9h 20m

$523

CharlestonAmarillo

CHS - AMA

CHSAMA

Charleston

Wed 2/25

3:45 pm-8:06 pm

1 stop5h 21m

Amarillo

Sun 3/1

12:30 pm-6:31 pm

1 stop5h 01m

$547

CharlestonAmarillo

CHS - AMA

CHSAMA

Charleston

Wed 2/25

11:40 am-9:30 pm

2 stops10h 50m

Amarillo

Sun 3/1

2:30 pm-8:10 pm

1 stop4h 40m

$552

GreenvilleAmarillo

GSP - AMA

GSPAMA

Greenville

Thu 6/25

11:18 am-10:30 pm

2 stops12h 12m

Amarillo

Mon 6/29

3:15 pm-10:11 pm

1 stop5h 56m

$598

CharlestonAmarillo

CHS - AMA

CHSAMA

Charleston

Sat 4/4

7:19 pm-11:59 pm

1 stop5h 40m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/9

Showing 1-10 of 11 results
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Best time to book a flight from South Carolina to Amarillo

Have a flexible travel schedule? Discover the best time to fly to Amarillo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Amarillo

What is the cheapest time of day to fly from SC to AMA?

Find hourly flight availability from South Carolina to Amarillo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 11, 2026.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 22% on flights from South Carolina to Amarillo by exploring options for tickets at noon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Amarillo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Amarillo from South Carolina?

    If you book a flight to Amarillo from South Carolina, you will be flying to Amarillo, which is the city’s only airport. Amarillo (AMA) is located 6.9 mi from the center of Amarillo.

  • How long is the flight from South Carolina to Amarillo?

    A quick flight from South Carolina to Amarillo can take about 5h 21m. United Airlines provides one of the quickest options available for as low as $407. Airlines will cover a distance of 1100 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Amarillo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Amarillo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Amarillo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Amarillo.

  • Can I find deals for business class flights from South Carolina to Amarillo?

    Yes. Cheapflights offers flight deals from South Carolina to Amarillo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Amarillo?

Book flights to Amarillo if you plan to visit one of these locations
Dalhart
Dumas

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Alternative routes for South Carolina to Amarillo

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Amarillo

Discover the top airline that operate flights from South Carolina to Amarillo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$296Average$375FlexibilityNo cancel feeOn-time71%

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