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$285+ Cheap flights from Knoxville to Tucson (TYS - TUS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — TUS
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Knoxville to Tucson

Cheapest flights from Knoxville to Tucson
Explore the most affordable flight options available from Knoxville to Tucson. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:29 amTYS - TUS
1 stop9h 40mDelta
Fri 12/121:49 pmTUS - TYS
1 stop7h 39mDelta
Deal found 11/12$398
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:24 amTYS - TUS
2 stops10h 47mAmerican Airlines
Fri 12/124:54 pmTUS - TYS
1 stop5h 05mAmerican Airlines
Deal found 11/12$403
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:10 amTYS - TUS
1 stop6h 29mAmerican Airlines
Mon 12/110:29 amTUS - TYS
1 stop4h 59mAmerican Airlines
Deal found 11/12$473
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:10 amTYS - TUS
1 stop6h 29mAmerican Airlines
Thu 12/44:42 pmTUS - TYS
1 stop5h 08mAmerican Airlines
Deal found 11/12$546
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:23 amTYS - TUS
1 stop6h 17mAmerican Airlines
Sun 12/286:00 amTUS - TYS
1 stop7h 56mAmerican Airlines
Deal found 11/11$602

Cheap flight deals from Knoxville to Tucson

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Tucson (TUS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$359
(Delta)

One-way from

$285
(Kiwi.com)

Popular in

October

Cheapest in

January

Average price

$491
Provider with most accurate pricing for Knoxville McGhee Tyson-Tucson flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Tucson flights.
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From Knoxville McGhee Tyson to Tucson
Search Deals
One-way flight from Knoxville McGhee Tyson to Tucson
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($107 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Tucson that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Knoxville to Tucson that are best for you.

Fly from

Knoxville

Fly to

Tucson

Route

Depart

Return

Price

KnoxvilleTucson

TYS - TUS

TYSTUS

Knoxville McGhee Tyson

Wed 2/11

11:58 am-4:44 pm

1 stop6h 46m

Tucson

Wed 2/18

4:03 pm-11:50 pm

1 stop5h 47m

$359

KnoxvilleTucson

TYS - TUS

TYSTUS

Knoxville McGhee Tyson

Wed 2/11

12:21 pm-9:47 pm

2 stops11h 26m

Tucson

Wed 2/18

12:53 pm-12:13 am

2 stops9h 20m

$369

KnoxvilleTucson

TYS - TUS

TYSTUS

Knoxville McGhee Tyson

Tue 12/9

6:00 pm-11:45 pm

1 stop7h 45m

Tucson

Fri 12/12

3:04 pm-11:18 pm

1 stop6h 14m

$398

KnoxvilleTucson

TYS - TUS

TYSTUS

Knoxville McGhee Tyson

Tue 12/9

5:24 am-2:11 pm

2 stops10h 47m

Tucson

Fri 12/12

9:09 am-5:27 pm

1 stop6h 18m

$403

KnoxvilleTucson

TYS - TUS

TYSTUS

Knoxville McGhee Tyson

Mon 1/12

12:19 pm-8:32 pm

2 stops10h 13m

Tucson

Fri 1/16

9:56 am-10:47 pm

2 stops10h 51m

$421

KnoxvilleTucson

TYS - TUS

TYSTUS

Knoxville McGhee Tyson

Mon 11/17

8:00 am-1:35 pm

1 stop7h 35m

$285

KnoxvilleTucson

TYS - TUS

TYSTUS

Knoxville McGhee Tyson

Sun 11/16

6:35 am-2:08 pm

1 stop9h 33m

$384

KnoxvilleTucson

TYS - TUS

TYSTUS

Knoxville McGhee Tyson

Mon 11/17

3:17 pm-10:59 pm

2 stops9h 42m

$389

KnoxvilleTucson

TYS - TUS

TYSTUS

Knoxville McGhee Tyson

Sun 11/16

5:05 am-11:43 am

2 stops8h 38m

$389

KnoxvilleTucson

TYS - TUS

TYSTUS

Knoxville McGhee Tyson

Sun 11/16

9:54 am-1:35 pm

3 stops29h 41m

$574

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Compare providers for flights from Knoxville to Tucson

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Tucson in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Tucson flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Tucson flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Tucson flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Tucson flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Tucson flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Tucson

Have a flexible travel schedule? Discover the best time to fly to Tucson from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Tucson

What is the cheapest month to book a flight from Knoxville to Tucson?

Currently, May is the cheapest month in which you can book a flight from Knoxville to Tucson (average of $138). Flying from Knoxville to Tucson in June is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to TUS?

Find hourly flight availability from Knoxville to Tucson. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Tucson in the afternoon. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Tucson

Get insights into the airlines that provide service to Tucson. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Tucson. Reviews last updated November 13, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Tucson to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,017 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Tucson. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Tucson?

    Delta and American Airlines can get you from Knoxville to Tucson in just under 6h 46m. Your travel time can differ by up to 4h 40m. Airlines will cover a distance of 1559 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Tucson round-trip?

    American Airlines, at $258, was found to be the cheapest airline from Knoxville to Tucson.Alternate airlines to your destination round-trip include Delta and United Airlines. American Airlines is 39% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Tucson that include hotel bookings?

    Yes. In addition to deals on Knoxville to Tucson flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Tucson?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Tucson.

  • Can I find deals for business class flights from Knoxville to Tucson?

    Yes. Cheapflights offers flight deals from Knoxville to Tucson by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Tucson?

    Currently, May is the cheapest month in which you can book a flight from Knoxville to Tucson (average of $138). Flying from Knoxville to Tucson in June is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Tucson?

Book flights to Tucson if you plan to visit one of these locations
Sierra Vista
Green Valley

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Top 3 airlines flying from Knoxville to Tucson

Discover the top 3 airlines that operate flights from Knoxville to Tucson. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$366FlexibilityNo cancel feeOn-time71%
DeltaCheapest$288Average$313FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$332Average$536FlexibilityNo cancel feeOn-time69%

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