$141+ Cheap flights from Missouri to Syracuse (SYR)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SYR
Oct 5 — Oct 121
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to SyracuseExplore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
Explore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
This CheapOair deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:30 pm -
1 stop23h 16m
Mon 10/265:31 pm -
1 stop6h 42m
Deal found 9/4![Frontier logo]()
$268
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:46 pm -
1 stop5h 12m
Sat 9/125:05 pm -
1 stop7h 37m
Deal found 9/3![Delta logo]()
$301
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:35 pm -
1 stop5h 20m
Sat 10/246:59 pm -
1 stop5h 55m
Deal found 9/1![Delta logo]()
$310
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:35 pm -
1 stop5h 20m
Sun 11/16:59 pm -
1 stop5h 55m
Deal found 9/3![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:00 am -
2 stops8h 12m
Sun 11/86:00 am -
1 stop5h 32m
Deal found 8/31![United Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop4h 40m
Wed 9/165:13 am -
1 stop6h 02m
Deal found 8/31![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:46 pm -
1 stop5h 00m
Wed 10/146:07 am -
1 stop5h 19m
Deal found 9/1![United Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
2 stops7h 14m
Wed 9/166:10 am -
1 stop6h 47m
Deal found 8/31![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:54 am -
1 stop7h 01m
Mon 9/215:40 pm -
1 stop4h 44m
Deal found 8/31![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:12 pm -
1 stop4h 53m
Sat 9/196:15 am -
1 stop5h 23m
Deal found 8/31![United Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:31 pm -
1 stop4h 26m
Sun 10/186:22 am -
1 stop4h 27m
Deal found 9/4![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:44 am -
2 stops8h 16m
Sat 9/196:00 am -
1 stop4h 56m
Deal found 8/31![American Airlines logo]()
$344
Best flights from Missouri to SyracuseDiscover carefully curated flight deals from Missouri to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
Discover carefully curated flight deals from Missouri to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:31 pm -
1 stop4h 26m
Tue 10/276:22 am -
1 stop4h 27m
Deal found 9/3![Delta logo]()
$301
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:00 am -
1 stop4h 45m
Sun 11/86:00 am -
1 stop7h 10m
Deal found 9/1![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:44 am -
2 stops10h 26m
Sat 9/1910:50 am -
2 stops10h 56m
Deal found 8/31![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:35 pm -
1 stop5h 20m
Sat 10/246:59 pm -
1 stop5h 55m
Deal found 9/1![Delta logo]()
$310
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:12 pm -
1 stop4h 53m
Sat 9/196:15 am -
1 stop5h 23m
Deal found 8/31![United Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:35 pm -
1 stop5h 20m
Sun 10/186:22 am -
1 stop4h 27m
Deal found 9/1![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:09 pm -
2 stops7h 38m
Sat 9/195:00 pm -
1 stop6h 32m
Deal found 8/31![American Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:43 am -
2 stops8h 24m
Sat 9/195:48 pm -
1 stop4h 45m
Deal found 8/31![United Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:14 pm -
2 stops7h 32m
Tue 10/206:07 am -
1 stop5h 19m
Deal found 9/4![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:19 pm -
1 stop7h 39m
Sat 9/195:05 pm -
1 stop5h 11m
Deal found 8/31![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:34 pm -
1 stop5h 24m
Mon 10/512:17 pm -
1 stop5h 37m
Deal found 8/31![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:18 pm -
1 stop5h 12m
Sat 1/98:00 am -
1 stop9h 03m
Deal found 9/1![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:35 pm -
1 stop5h 20m
Sun 10/186:22 am -
1 stop4h 27m
Deal found 9/4![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:59 pm -
1 stop7h 06m
Mon 9/215:48 pm -
1 stop6h 11m
Deal found 8/31![United Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/233:00 pm -
1 stop5h 30m
Tue 1/266:00 am -
1 stop5h 55m
Deal found 8/31![United Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
2 stops7h 07m
Fri 1/16:00 am -
1 stop5h 44m
Deal found 9/4![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/183:58 pm -
1 stop6h 55m
Sat 1/26:00 am -
1 stop4h 50m
Deal found 8/31![Delta logo]()
$493
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:50 pm -
1 stop4h 53m
Tue 11/310:17 am -
2 stops8h 08m
Deal found 8/31![United Airlines logo]()
$448
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:39 pm -
1 stop4h 39m
Mon 10/266:59 pm -
1 stop5h 57m
Deal found 9/4![Delta logo]()
$524
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:00 am -
1 stop4h 45m
Tue 11/105:20 pm -
1 stop5h 15m
Deal found 9/1![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:37 pm -
1 stop8h 44m
Tue 9/225:48 pm -
1 stop5h 14m
Deal found 9/3![United Airlines logo]()
$451
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:19 am -
1 stop4h 35m
Wed 10/282:55 pm -
2 stops9h 03m
Deal found 9/4![United Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:55 am -
1 stop5h 51m
Wed 9/2312:11 pm -
1 stop5h 01m
Deal found 9/3![United Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/61:41 pm -
1 stop8h 42m
Sat 1/98:00 am -
1 stop9h 23m
Deal found 9/2![United Airlines logo]()
$479
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/93:13 pm -
1 stop5h 17m
Tue 1/126:00 am -
1 stop5h 37m
Deal found 9/4![United Airlines logo]()
$559
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:01 am -
1 stop27h 44m
Wed 11/118:00 am -
1 stop16h 44m
Deal found 9/2![United Airlines logo]()
$698
Last-minute flights from Missouri to SyracuseDiscover last-minute flight deals from Missouri to Syracuse. Data last updated September 5, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Syracuse. Data last updated September 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop4h 40m
Wed 9/165:13 am -
1 stop6h 02m
Deal found 8/31![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
2 stops7h 14m
Wed 9/166:10 am -
1 stop6h 47m
Deal found 8/31![United Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:46 pm -
1 stop5h 12m
Sat 9/125:05 pm -
1 stop7h 37m
Deal found 9/3![Delta logo]()
$301
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:12 pm -
1 stop4h 53m
Sat 9/196:15 am -
1 stop5h 23m
Deal found 8/31![United Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:44 am -
2 stops8h 16m
Sat 9/196:00 am -
1 stop4h 56m
Deal found 8/31![American Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:00 am -
1 stop4h 40m
Sat 9/195:00 pm -
1 stop5h 44m
Deal found 8/31![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:54 am -
1 stop7h 01m
Mon 9/215:40 pm -
1 stop4h 44m
Deal found 8/31![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:46 pm -
1 stop5h 00m
Wed 10/146:07 am -
1 stop5h 19m
Deal found 9/1![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:35 pm -
1 stop5h 20m
Sat 10/246:59 pm -
1 stop5h 55m
Deal found 9/1![Delta logo]()
$310
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:31 pm -
1 stop4h 26m
Sun 10/186:22 am -
1 stop4h 27m
Deal found 9/4![Delta logo]()
$339
This CheapOair deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:30 pm -
1 stop23h 16m
Mon 10/265:31 pm -
1 stop6h 42m
Deal found 9/4![Frontier logo]()
$268
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:35 pm -
1 stop5h 20m
Sun 11/16:59 pm -
1 stop5h 55m
Deal found 9/2![Delta logo]()
$319
One-way flights from Missouri to SyracuseSearch for one-way flight options from Missouri to Syracuse. Find affordable one-way fares based on user searches. Data last updated September 5, 2026.
Search for one-way flight options from Missouri to Syracuse. Find affordable one-way fares based on user searches. Data last updated September 5, 2026.
This Trip.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:30 pm -
1 stop23h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:35 pm -
2 stops38h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:30 pm -
2 stops18h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$250
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:40 pm -
1 stop4h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:34 pm -
1 stop5h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:32 am -
1 stop6h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
2 stops7h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![United Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:48 pm -
1 stop8h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:08 am -
2 stops9h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Delta logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:39 pm -
2 stops25h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$324
This KAYAK deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:01 am -
1 stop4h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![American Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:32 pm -
3 stops25h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Allegiant Air logo]()
$377
Find flight deals from Missouri to Syracuse
Keep the following information in mind while searching for Missouri to Syracuse flight deals. Data was last updated September 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $268 (CheapOair) |
One-way from | $141 (Trip.com) |
Popular in | March |
Cheapest in | September |
Average price | $294 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
Use the filters below to find and compare flights from Missouri to Syracuse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSyracuse
STL Lambert-St Louis - SYR Syracuse Hancock Intl
STLSYR
Lambert-St Louis
Fri 10/9
6:35 pm-10:08 am
2 stops38h 33m
Syracuse Hancock Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$153
St. LouisSyracuse
STL Lambert-St Louis - SYR Syracuse Hancock Intl
STLSYR
Lambert-St Louis
Thu 10/22
5:53 pm-2:40 pm
3 stops43h 47m
Syracuse Hancock Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$265
St. LouisSyracuse
STL Lambert-St Louis - SYR Syracuse Hancock Intl
STLSYR
Lambert-St Louis
Thu 10/22
5:40 pm-11:29 pm
1 stop4h 49m
Syracuse Hancock Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$274
St. LouisSyracuse
STL Lambert-St Louis - SYR Syracuse Hancock Intl
STLSYR
Lambert-St Louis
Tue 10/13
5:31 pm-10:57 pm
1 stop4h 26m
Syracuse Hancock Intl
Tue 10/27
6:22 am-9:49 am
1 stop4h 27m
$301
SpringfieldSyracuse
SGF Springfield-Branson - SYR Syracuse Hancock Intl
SGFSYR
Springfield-Branson
Wed 9/30
6:00 am-11:53 am
1 stop4h 53m
Syracuse Hancock Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$309
SpringfieldSyracuse
SGF Springfield-Branson - SYR Syracuse Hancock Intl
SGFSYR
Springfield-Branson
Mon 9/28
5:34 pm-11:58 pm
1 stop5h 24m
Syracuse Hancock Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$309
Kansas CitySyracuse
MCI Kansas City - SYR Syracuse Hancock Intl
MCISYR
Kansas City
Wed 11/25
10:32 am-6:03 pm
1 stop6h 31m
Syracuse Hancock Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$309
St. LouisSyracuse
STL Lambert-St Louis - SYR Syracuse Hancock Intl
STLSYR
Lambert-St Louis
Fri 10/16
5:35 pm-11:55 pm
1 stop5h 20m
Syracuse Hancock Intl
Sat 10/24
6:59 pm-11:54 pm
1 stop5h 55m
$310
Kansas CitySyracuse
MCI Kansas City - SYR Syracuse Hancock Intl
MCISYR
Kansas City
Fri 10/2
1:48 pm-11:32 pm
1 stop8h 44m
Syracuse Hancock Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$319
St. LouisSyracuse
STL Lambert-St Louis - SYR Syracuse Hancock Intl
STLSYR
Lambert-St Louis
Thu 11/5
5:00 am-10:45 am
1 stop4h 45m
Syracuse Hancock Intl
Sun 11/8
6:00 am-12:10 pm
1 stop7h 10m
$319
Showing 1-10 of 47 resultsSorted by cheapest first
Best time to book a flight from Missouri to Syracuse
Have a flexible travel schedule? Discover the best time to fly to Syracuse from Missouri with our price prediction graph.
STL-SYR
MCI-SYR
COU-SYR
SGF-SYR
JLN-SYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Syracuse
USMO-SYR
STL-SYR
MCI-SYR
COU-SYR
SGF-SYR
What is the cheapest month to book a flight from Missouri to Syracuse?
Currently, September is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $318). Flying from Missouri to Syracuse in July is currently the most expensive (average of $573). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Syracuse?
Airfare is below average for this route at the moment.
Missouri to Syracuse flights typically cost between $294 and $318 in October.The cheapest round-trip price found within the last 5 days was $268 on Frontier (Oct 22-Oct 26).
Related info for your journey
Find useful and relevant information for your journey from Missouri to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Syracuse?
Book flights to Syracuse if you plan to visit one of these locationsEast Syracuse
Liverpool
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Alternative routes for Missouri to Syracuse
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Missouri and Syracuse flights
Browse other Missouri and Syracuse flight options. Last updated on September 5, 2026.
Popular flight searches
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Other flights to Syracuse
Explore flights to Syracuse departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 5, 2026.
Missouri to Syracuse flights
Consider these flights traveling from Missouri to Syracuse.
Top 3 airlines flying from Missouri to Syracuse
Discover the top 3 airlines that operate flights from Missouri to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$191 | Average$404 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$246 | Average$442 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$434 | FlexibilityNo cancel fee | On-timeN/A |