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Syracuse

$169+ Cheap flights from Missouri to Syracuse (SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SYR
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Missouri to Syracuse

Cheapest flights from Missouri to Syracuse
Explore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Delta deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:32 pm
SGF
-
SYR
1 stop5h 35m
Delta
Tue 2/2412:05 pm
SYR
-
SGF
1 stop5h 42m
Delta
Deal found 1/18$251
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:05 pm
SGF
-
SYR
1 stop4h 39m
American Airlines
Tue 2/246:00 am
SYR
-
SGF
2 stops8h 49m
American Airlines
Deal found 1/18$256
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:37 am
STL
-
SYR
1 stop5h 38m
American Airlines
Tue 3/34:11 pm
SYR
-
STL
1 stop7h 53m
American Airlines
Deal found 1/19$260
This United Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/410:10 am
STL
-
SYR
1 stop5h 05m
United Airlines
Sun 2/88:00 am
SYR
-
STL
1 stop7h 30m
United Airlines
Deal found 1/18$274
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/49:45 am
STL
-
SYR
1 stop6h 29m
Delta
Sat 2/75:50 am
SYR
-
STL
1 stop4h 44m
Delta
Deal found 1/20$279
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:38 pm
MCI
-
SYR
1 stop4h 33m
Delta
Sat 4/185:20 pm
SYR
-
MCI
1 stop4h 25m
Delta
Deal found 1/20$279
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/274:22 pm
MCI
-
SYR
1 stop6h 24m
American Airlines
Sat 3/73:25 pm
SYR
-
MCI
2 stops9h 34m
American Airlines
Deal found 1/19$284
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/310:50 am
MCI
-
SYR
1 stop4h 37m
American Airlines
Tue 2/175:00 pm
SYR
-
MCI
1 stop7h 00m
American Airlines
Deal found 1/20$294
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/36:30 am
STL
-
SYR
2 stops6h 37m
United Airlines
Sat 2/77:03 am
SYR
-
STL
2 stops8h 25m
United Airlines
Deal found 1/19$299
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/275:00 am
MCI
-
SYR
1 stop5h 11m
American Airlines
Sat 4/117:01 am
SYR
-
MCI
1 stop7h 46m
American Airlines
Deal found 1/20$303
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/26:35 am
STL
-
SYR
1 stop4h 26m
Delta
Sat 2/75:50 am
SYR
-
STL
1 stop4h 44m
Delta
Deal found 1/21$309
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/31:42 pm
MCI
-
SYR
1 stop8h 31m
United Airlines
Sat 2/74:57 pm
SYR
-
MCI
1 stop6h 02m
United Airlines
Deal found 1/19$309

Find flight deals from Missouri to Syracuse

Keep the following information in mind while searching for Missouri to Syracuse flight deals. Data was last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$251
(Delta)

One-way from

$169
(Kiwi.com)

Popular in

May

Cheapest in

September

Average price

$348
Provider with most accurate pricing for Lambert-St Louis-Syracuse Hancock Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Syracuse Hancock Intl flights.
Search Deals
From Missouri to Syracuse Hancock Intl
Search Deals
One-way flight from Missouri to Syracuse Hancock Intl
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Missouri to Syracuse that are best for you.

Fly from

Missouri

Fly to

Syracuse

Route

Depart

Return

Price

SpringfieldSyracuse

SGF - SYR

SGFSYR

Springfield-Branson

Tue 2/17

5:32 pm-12:07 am

1 stop5h 35m

Syracuse Hancock Intl

Tue 2/24

12:05 pm-4:47 pm

1 stop5h 42m

$251

SpringfieldSyracuse

SGF - SYR

SGFSYR

Springfield-Branson

Tue 2/17

6:05 pm-11:44 pm

1 stop4h 39m

Syracuse Hancock Intl

Tue 2/24

6:00 am-1:49 pm

2 stops8h 49m

$256

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Thu 2/26

9:37 am-4:15 pm

1 stop5h 38m

Syracuse Hancock Intl

Tue 3/3

4:11 pm-11:04 pm

1 stop7h 53m

$260

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Wed 2/4

10:10 am-4:15 pm

1 stop5h 05m

Syracuse Hancock Intl

Sun 2/8

8:00 am-2:30 pm

1 stop7h 30m

$274

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Wed 2/4

10:10 am-4:15 pm

1 stop5h 05m

Syracuse Hancock Intl

Sat 2/7

8:00 am-2:28 pm

1 stop7h 28m

$279

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Mon 2/2

5:56 pm-11:13 pm

1 stop4h 17m

Syracuse Hancock Intl

Sat 2/7

12:41 pm-4:37 pm

1 stop4h 56m

$279

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Wed 2/4

5:56 pm-11:13 pm

1 stop4h 17m

Syracuse Hancock Intl

Sat 2/7

5:50 am-9:34 am

1 stop4h 44m

$279

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Tue 2/3

5:56 pm-11:13 pm

1 stop4h 17m

Syracuse Hancock Intl

Sat 2/7

3:00 pm-7:27 pm

1 stop5h 27m

$279

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Tue 4/14

5:38 pm-11:11 pm

1 stop4h 33m

Syracuse Hancock Intl

Sat 4/18

5:20 pm-8:45 pm

1 stop4h 25m

$279

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Tue 4/14

5:42 pm-11:09 pm

1 stop4h 27m

Syracuse Hancock Intl

Sun 4/19

5:45 pm-10:19 pm

1 stop5h 34m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 38 results
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Best time to book a flight from Missouri to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Syracuse

What is the cheapest month to book a flight from Missouri to Syracuse?

Currently, July is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $155). Flying from Missouri to Syracuse in December is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Syracuse from Missouri?

    Located just 4.8 mi from the city center, Syracuse Hancock Intl (SYR) is the airport most travelers will use when flying to Syracuse from Missouri.

  • How long is the flight from Missouri to Syracuse?

    There are many flights that can get you from Missouri to Syracuse in 4h 39m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. The distance between Missouri and Syracuse is about 995 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Missouri to Syracuse?

    While some choose either Lambert-St Louis - Syracuse Hancock Intl or Springfield-Branson - Syracuse Hancock Intl, Kansas City - Syracuse Hancock Intl is the most popular route from Missouri to Syracuse.

  • Can I find deals for flights from Missouri to Syracuse that include hotel bookings?

    Yes. In addition to deals on Missouri to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Syracuse.

  • Can I find deals for business class flights from Missouri to Syracuse?

    Yes. Cheapflights offers flight deals from Missouri to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Syracuse?

    Currently, July is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $155). Flying from Missouri to Syracuse in December is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
Liverpool
East Syracuse
Waterloo

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Alternative routes for Missouri to Syracuse

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Syracuse

Discover the top 3 airlines that operate flights from Missouri to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$412FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$326FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$268Average$367FlexibilityNo cancel feeOn-time69%

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