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Syracuse

$148+ Cheap flights from Missouri to Syracuse (SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — SYR
Jul 7 — Jul 141
Tue 7/7
Tue 7/14
1 adult, Economy
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Cheap flight deals from Missouri to Syracuse

Cheapest flights from Missouri to Syracuse
Explore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 7, 2026.

This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:04 pm
STL
-
SYR
1 stop3h 54m
Delta
Tue 8/46:20 am
SYR
-
STL
1 stop4h 17m
Delta
Deal found 6/3$291
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:10 pm
STL
-
SYR
1 stop3h 47m
Delta
Sat 7/116:21 am
SYR
-
STL
1 stop4h 10m
Delta
Deal found 6/6$295
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:29 pm
STL
-
SYR
2 stops9h 15m
United Airlines
Sat 10/245:50 pm
SYR
-
STL
1 stop4h 31m
United Airlines
Deal found 6/6$296
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:48 pm
STL
-
SYR
1 stop4h 37m
American Airlines
Sat 8/158:12 pm
SYR
-
STL
1 stop4h 46m
American Airlines
Deal found 6/3$300
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
STL
-
SYR
2 stops7h 14m
United Airlines
Tue 8/256:00 am
SYR
-
STL
2 stops7h 02m
United Airlines
Deal found 6/2$301
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/239:22 am
STL
-
SYR
1 stop7h 02m
Delta
Tue 6/306:00 am
SYR
-
STL
1 stop6h 40m
Delta
Deal found 6/2$309
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2912:18 pm
MCI
-
SYR
1 stop5h 26m
Delta
Sat 9/56:00 am
SYR
-
MCI
1 stop6h 11m
Delta
Deal found 6/2$319
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:20 am
STL
-
SYR
1 stop5h 15m
Delta
Wed 6/246:11 am
SYR
-
STL
1 stop4h 21m
Delta
Deal found 6/3$324
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:06 pm
MCI
-
SYR
1 stop6h 15m
Delta
Sun 8/166:20 am
SYR
-
MCI
1 stop4h 25m
Delta
Deal found 6/4$329
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:45 am
STL
-
SYR
1 stop7h 26m
American Airlines
Wed 7/14:52 pm
SYR
-
STL
1 stop4h 40m
American Airlines
Deal found 6/6$334
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:22 pm
STL
-
SYR
1 stop4h 47m
Delta
Sun 6/216:11 am
SYR
-
STL
1 stop4h 21m
Delta
Deal found 6/3$339
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:40 pm
MCI
-
SYR
1 stop4h 18m
Delta
Tue 8/46:20 am
SYR
-
MCI
1 stop4h 25m
Delta
Deal found 6/2$339

Find flight deals from Missouri to Syracuse

Keep the following information in mind while searching for Missouri to Syracuse flight deals. Data was last updated June 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$291
(Delta)

One-way from

$148
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$336
Provider with most accurate pricing for Lambert-St Louis-Syracuse Hancock Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Syracuse Hancock Intl flights.
Search Deals
From Missouri to Syracuse Hancock Intl
Search Deals
One-way flight from Missouri to Syracuse Hancock Intl
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($71 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
Use the filters below to find and compare flights from Missouri to Syracuse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Tue 10/20

5:46 pm-11:45 pm

1 stop4h 59m

Syracuse Hancock Intl

Sat 10/24

7:50 am-1:03 pm

1 stop6h 13m

$291

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Sat 8/1

6:04 pm-10:58 pm

1 stop3h 54m

Syracuse Hancock Intl

Tue 8/4

6:20 am-9:37 am

1 stop4h 17m

$291

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Tue 10/20

1:29 pm-11:44 pm

2 stops9h 15m

Syracuse Hancock Intl

Sat 10/24

5:50 pm-9:21 pm

1 stop4h 31m

$296

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Sat 7/4

4:10 pm-10:57 pm

1 stop5h 47m

Syracuse Hancock Intl

Sat 7/11

11:19 am-6:07 pm

1 stop7h 48m

$369

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Sat 11/14

9:23 am-4:57 pm

1 stop6h 34m

Syracuse Hancock Intl

Tue 11/17

6:00 am-2:18 pm

2 stops9h 18m

$376

ColumbiaSyracuse

COU - SYR

COUSYR

Columbia Regional

Wed 9/2

10:55 am-4:52 pm

1 stop4h 57m

Syracuse Hancock Intl

Sat 9/5

5:48 pm-10:55 pm

1 stop6h 07m

$378

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Sun 8/2

5:40 pm-10:58 pm

1 stop4h 18m

Syracuse Hancock Intl

Sat 8/8

6:00 am-11:11 am

1 stop6h 11m

$379

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Wed 7/29

5:40 pm-10:58 pm

1 stop4h 18m

Syracuse Hancock Intl

Tue 8/4

6:20 am-9:45 am

1 stop4h 25m

$379

JoplinSyracuse

JLN - SYR

JLNSYR

Joplin

Wed 12/2

8:52 am-4:57 pm

1 stop7h 05m

Syracuse Hancock Intl

Sat 12/5

5:33 pm-11:19 pm

1 stop6h 46m

$404

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Sat 7/4

6:00 am-1:32 pm

1 stop6h 32m

Syracuse Hancock Intl

Fri 7/10

4:15 pm-11:25 pm

1 stop8h 10m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/3

Showing 1-10 of 45 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Syracuse

What is the cheapest month to book a flight from Missouri to Syracuse?

Currently, October is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $206). Flying from Missouri to Syracuse in March is currently the most expensive (average of $348). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Syracuse?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Syracuse from Missouri?

    Located just 4.8 mi from the city center, Syracuse Hancock Intl (SYR) is the airport most travelers will use when flying to Syracuse from Missouri.

  • How long is the flight from Missouri to Syracuse?

    There are many flights that can get you from Missouri to Syracuse in 3h 54m. Fly via American Airlines, Delta, or United Airlines to get the fastest option. The distance between Missouri and Syracuse is about 801 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Syracuse one-way?

    One-way options have recently been found by users for as low as $63 on American Airlines. Other airlines that offer cheap prices include Delta from $172 and United Airlines from $267 one-way.

  • What are the most popular routes from Missouri to Syracuse?

    While some choose either Lambert-St Louis - Syracuse Hancock Intl or Columbia Regional - Syracuse Hancock Intl, Kansas City - Syracuse Hancock Intl is the most popular route from Missouri to Syracuse.

  • Can I find deals for flights from Missouri to Syracuse that include hotel bookings?

    Yes. In addition to deals on Missouri to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Syracuse.

  • Can I find deals for business class flights from Missouri to Syracuse?

    Yes. Cheapflights offers flight deals from Missouri to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Syracuse?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $206). Flying from Missouri to Syracuse in March is currently the most expensive (average of $348). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
East Syracuse
Liverpool

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Alternative routes for Missouri to Syracuse

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Syracuse

Discover the top 3 airlines that operate flights from Missouri to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$246Average$418FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$376FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$268Average$374FlexibilityNo cancel feeOn-time69%

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