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Syracuse

$149+ Cheap flights from Missouri to Syracuse (SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SYR
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Missouri to Syracuse

Cheapest flights from Missouri to Syracuse
Explore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:45 pm
STL
-
SYR
1 stop4h 11m
Delta
Tue 8/411:25 am
SYR
-
STL
1 stop6h 15m
Delta
Deal found 2/1$251
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:06 am
STL
-
SYR
1 stop4h 33m
American Airlines
Tue 3/37:01 am
SYR
-
STL
1 stop7h 15m
American Airlines
Deal found 2/1$260
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:30 pm
STL
-
SYR
1 stop5h 28m
Delta
Mon 9/76:50 pm
SYR
-
STL
1 stop5h 47m
Delta
Deal found 2/2$269
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/172:06 pm
STL
-
SYR
1 stop7h 37m
American Airlines
Sat 2/215:24 pm
SYR
-
STL
1 stop5h 13m
American Airlines
Deal found 2/1$279
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:48 pm
MCI
-
SYR
1 stop6h 11m
Delta
Sun 3/155:50 am
SYR
-
MCI
1 stop5h 01m
Delta
Deal found 2/3$279
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:22 pm
SGF
-
SYR
1 stop7h 30m
Delta
Wed 5/205:35 am
SYR
-
SGF
2 stops10h 00m
Delta
Deal found 2/2$284
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:58 pm
MCI
-
SYR
1 stop7h 59m
American Airlines
Sat 3/73:25 pm
SYR
-
MCI
2 stops9h 34m
American Airlines
Deal found 2/1$284
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:00 am
MCI
-
SYR
1 stop5h 00m
Delta
Sun 3/295:50 am
SYR
-
MCI
1 stop5h 01m
Delta
Deal found 2/1$291
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:41 am
STL
-
SYR
2 stops11h 33m
United Airlines
Sun 3/86:25 am
SYR
-
STL
1 stop7h 02m
United Airlines
Deal found 2/1$307
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:05 pm
SGF
-
SYR
1 stop4h 39m
American Airlines
Sat 2/216:00 am
SYR
-
SGF
1 stop6h 18m
American Airlines
Deal found 2/2$309
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1712:37 pm
MCI
-
SYR
1 stop6h 37m
United Airlines
Sat 2/212:47 pm
SYR
-
MCI
1 stop6h 19m
United Airlines
Deal found 2/2$309
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:45 am
MCI
-
SYR
2 stops28h 38m
Multiple Airlines
Mon 3/1611:37 am
SYR
-
MCI
1 stop24h 52m
Multiple Airlines
Deal found 2/3$323

Find flight deals from Missouri to Syracuse

Keep the following information in mind while searching for Missouri to Syracuse flight deals. Data was last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$251
(Delta)

One-way from

$149
(Kiwi.com)

Popular in

May

Cheapest in

September

Average price

$354
Provider with most accurate pricing for Lambert-St Louis-Syracuse Hancock Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Syracuse Hancock Intl flights.
Search Deals
From Missouri to Syracuse Hancock Intl
Search Deals
One-way flight from Missouri to Syracuse Hancock Intl
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($3 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Missouri to Syracuse that are best for you.

Fly from

Missouri

Fly to

Syracuse

Route

Depart

Return

Price

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Sat 8/1

5:45 pm-10:56 pm

1 stop4h 11m

Syracuse Hancock Intl

Tue 8/4

11:25 am-4:40 pm

1 stop6h 15m

$251

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Thu 2/26

6:06 am-11:39 am

1 stop4h 33m

Syracuse Hancock Intl

Tue 3/3

7:01 am-1:16 pm

1 stop7h 15m

$260

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Fri 5/29

1:13 pm-9:19 pm

1 stop7h 06m

Syracuse Hancock Intl

Tue 6/2

5:44 pm-9:11 pm

1 stop4h 27m

$260

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Fri 5/29

10:43 am-5:50 pm

1 stop6h 07m

Syracuse Hancock Intl

Tue 6/2

6:00 am-12:23 pm

1 stop7h 23m

$260

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Wed 5/27

5:15 pm-11:52 pm

1 stop5h 37m

Syracuse Hancock Intl

Sun 5/31

6:59 pm-11:59 pm

1 stop6h 00m

$260

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Tue 2/17

2:06 pm-10:43 pm

1 stop7h 37m

Syracuse Hancock Intl

Sat 2/21

5:24 pm-9:37 pm

1 stop5h 13m

$279

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Fri 3/27

6:00 am-12:00 pm

1 stop5h 00m

Syracuse Hancock Intl

Sat 4/11

12:16 pm-4:55 pm

1 stop5h 39m

$279

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Thu 6/11

5:40 am-2:11 pm

1 stop7h 31m

Syracuse Hancock Intl

Wed 6/17

6:00 am-12:21 pm

1 stop7h 21m

$279

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Tue 6/9

5:26 pm-11:59 pm

1 stop5h 33m

Syracuse Hancock Intl

Wed 6/17

6:50 pm-11:55 pm

1 stop6h 05m

$279

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Sat 6/6

5:12 pm-11:52 pm

1 stop5h 40m

Syracuse Hancock Intl

Wed 6/17

6:50 pm-11:55 pm

1 stop6h 05m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 36 results
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Best time to book a flight from Missouri to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Syracuse

What is the cheapest month to book a flight from Missouri to Syracuse?

Currently, July is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $155). Flying from Missouri to Syracuse in December is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Syracuse from Missouri?

    Located just 4.8 mi from the city center, Syracuse Hancock Intl (SYR) is the airport most travelers will use when flying to Syracuse from Missouri.

  • How long is the flight from Missouri to Syracuse?

    There are many flights that can get you from Missouri to Syracuse in 4h 11m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. The distance between Missouri and Syracuse is about 801 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Missouri to Syracuse?

    While some choose either Lambert-St Louis - Syracuse Hancock Intl or Springfield-Branson - Syracuse Hancock Intl, Kansas City - Syracuse Hancock Intl is the most popular route from Missouri to Syracuse.

  • Can I find deals for flights from Missouri to Syracuse that include hotel bookings?

    Yes. In addition to deals on Missouri to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Syracuse.

  • Can I find deals for business class flights from Missouri to Syracuse?

    Yes. Cheapflights offers flight deals from Missouri to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Syracuse?

    Currently, July is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $155). Flying from Missouri to Syracuse in December is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
Liverpool
East Syracuse
Waterloo

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Alternative routes for Missouri to Syracuse

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Syracuse

Discover the top 3 airlines that operate flights from Missouri to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$413FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$333FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$268Average$369FlexibilityNo cancel feeOn-time69%

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