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Syracuse

$168+ Cheap flights from Missouri to Syracuse (SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SYR
apr. 8 — apr. 151
wo 4/8
wo 4/15
1 adult, Economy
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Cheap flight deals from Missouri to Syracuse

Cheapest flights from Missouri to Syracuse
Explore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on maart 9, 2026.

This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 4/155:59 pm
STL
-
SYR
1 stop4h 11m
Delta
za 4/185:50 am
SYR
-
STL
1 stop4h 58m
Delta
Deal found 3/6$271
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 3/276:30 pm
COU
-
SYR
1 stop4h 14m
American Airlines
di 3/315:15 am
SYR
-
COU
1 stop5h 13m
American Airlines
Deal found 3/5$278
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/135:59 pm
STL
-
SYR
1 stop4h 11m
Delta
za 4/185:50 am
SYR
-
STL
1 stop4h 58m
Delta
Deal found 3/6$280
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/135:59 pm
STL
-
SYR
1 stop4h 11m
Delta
do 4/235:50 am
SYR
-
STL
1 stop4h 52m
Delta
Deal found 3/6$289
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 4/299:58 am
MCI
-
SYR
1 stop6h 03m
United Airlines
di 5/55:45 pm
SYR
-
MCI
1 stop5h 19m
United Airlines
Deal found 3/4$289
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 3/245:15 pm
STL
-
SYR
1 stop4h 23m
Delta
di 3/315:50 am
SYR
-
STL
1 stop4h 56m
Delta
Deal found 3/8$294
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 4/282:33 pm
MCI
-
SYR
1 stop7h 45m
American Airlines
wo 5/136:15 pm
SYR
-
MCI
1 stop6h 03m
American Airlines
Deal found 3/5$299
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 9/66:02 am
STL
-
SYR
1 stop4h 17m
American Airlines
di 9/158:15 pm
SYR
-
STL
1 stop4h 05m
American Airlines
Deal found 3/6$300
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 5/16:17 am
MCI
-
SYR
1 stop6h 14m
United Airlines
za 5/92:27 pm
SYR
-
MCI
2 stops10h 25m
United Airlines
Deal found 3/6$304
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 8/16:45 am
STL
-
SYR
1 stop4h 08m
Delta
di 8/49:30 am
SYR
-
STL
1 stop4h 47m
Delta
Deal found 3/5$305
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 9/66:00 am
STL
-
SYR
2 stops7h 09m
United Airlines
di 9/155:44 pm
SYR
-
STL
1 stop4h 38m
United Airlines
Deal found 3/6$308
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 8/275:27 am
STL
-
SYR
1 stop6h 25m
American Airlines
zo 8/301:01 pm
SYR
-
STL
1 stop6h 17m
American Airlines
Deal found 3/6$309

Find flight deals from Missouri to Syracuse

Keep the following information in mind while searching for Missouri to Syracuse flight deals. Data was last updated maart 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$271
(Delta)

One-way from

$168
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$448
Provider with most accurate pricing for Lambert-St Louis-Syracuse Hancock Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Syracuse Hancock Intl flights.
Search Deals
From Missouri to Syracuse Hancock Intl
Search Deals
One-way flight from Missouri to Syracuse Hancock Intl
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated maart 9, 2026.
Use the filters below to find and compare flights from Missouri to Syracuse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

wo 4/15

5:59 pm-11:10 pm

1 stop4h 11m

Syracuse Hancock Intl

di 4/21

5:50 am-9:42 am

1 stop4h 52m

$271

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

wo 4/29

9:58 am-5:01 pm

1 stop6h 03m

Syracuse Hancock Intl

di 5/5

5:45 pm-10:04 pm

1 stop5h 19m

$289

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

ma 4/13

5:59 pm-11:10 pm

1 stop4h 11m

Syracuse Hancock Intl

zo 4/19

5:50 am-9:42 am

1 stop4h 52m

$289

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

za 8/29

6:05 am-12:05 pm

1 stop5h 00m

Syracuse Hancock Intl

za 9/5

6:20 am-2:02 pm

1 stop8h 42m

$299

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

vr 5/1

1:50 pm-11:21 pm

1 stop8h 31m

Syracuse Hancock Intl

za 5/9

6:15 am-10:33 am

1 stop5h 18m

$299

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

di 4/28

2:33 pm-11:18 pm

1 stop7h 45m

Syracuse Hancock Intl

wo 5/13

6:15 pm-11:18 pm

1 stop6h 03m

$299

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

vr 4/3

5:42 pm-11:09 pm

1 stop4h 27m

Syracuse Hancock Intl

zo 4/5

5:45 am-10:38 am

1 stop5h 53m

$299

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

vr 4/17

5:46 pm-11:10 pm

1 stop4h 24m

Syracuse Hancock Intl

ma 4/20

6:25 pm-11:50 pm

1 stop6h 25m

$299

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

vr 4/3

5:42 pm-11:09 pm

1 stop4h 27m

Syracuse Hancock Intl

za 4/4

11:43 am-7:19 pm

1 stop8h 36m

$323

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

di 6/9

3:36 pm-11:59 pm

1 stop7h 23m

Syracuse Hancock Intl

di 6/16

6:50 pm-11:55 pm

1 stop6h 05m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/4

Showing 1-10 of 51 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Syracuse

What is the cheapest month to book a flight from Missouri to Syracuse?

Currently, July is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $155). Flying from Missouri to Syracuse in March is currently the most expensive (average of $291). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Syracuse from Missouri?

    Located just 4.8 mi from the city center, Syracuse Hancock Intl (SYR) is the airport most travelers will use when flying to Syracuse from Missouri.

  • How long is the flight from Missouri to Syracuse?

    There are many flights that can get you from Missouri to Syracuse in 4h 11m. Fly via Delta, United Airlines, or American Airlines to get the fastest option. The distance between Missouri and Syracuse is about 801 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Syracuse one-way?

    One-way options have recently been found by users for as low as $63 on American Airlines. Other airlines that offer cheap prices include United Airlines from $134 and Frontier from $141 one-way.

  • What are the most popular routes from Missouri to Syracuse?

    While some choose either Kansas City - Syracuse Hancock Intl or Columbia Regional - Syracuse Hancock Intl, Lambert-St Louis - Syracuse Hancock Intl is the most popular route from Missouri to Syracuse.

  • Can I find deals for flights from Missouri to Syracuse that include hotel bookings?

    Yes. In addition to deals on Missouri to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Syracuse.

  • Can I find deals for business class flights from Missouri to Syracuse?

    Yes. Cheapflights offers flight deals from Missouri to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Syracuse?

    Currently, July is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $155). Flying from Missouri to Syracuse in March is currently the most expensive (average of $291). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
Liverpool
East Syracuse
Waterloo

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Alternative routes for Missouri to Syracuse

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Syracuse

Discover the top 3 airlines that operate flights from Missouri to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated maart 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$391FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$337FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$268Average$354FlexibilityNo cancel feeOn-time69%

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