How long is the flight from Missouri to Syracuse?

There are many flights that can get you from Missouri to Syracuse in 4h 30m. Fly via United Airlines, American Airlines, or Delta to get the fastest option. The distance between Missouri and Syracuse is about 801 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Syracuse ranges from 2.1 - 3.8 inches per month. July is typically the wettest month, when rainfall can reach 3.8 in. February is typically the driest time to visit Syracuse when rainfall is around 2.1 in.

If weather is an important factor for your trip to Syracuse, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What are the most popular routes from Missouri to Syracuse?

While some choose either Kansas City - Syracuse Hancock Intl or Springfield-Branson - Syracuse Hancock Intl, Lambert-St Louis - Syracuse Hancock Intl is the most popular route from Missouri to Syracuse.

What are the most popular airlines that fly from Missouri to Syracuse?

When booking a flight from Missouri to Syracuse, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

How far in advance should I book a flight from Missouri to Syracuse?

Travelers have found it’s best to book a flight 28 days in advance to save up to 80% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 28 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Missouri to Syracuse 1-2 weeks in advance for as low as $257, or $358 for flights within the next 24 hours.

What is the cheapest month to fly from Missouri to Syracuse?

Due to multiple factors, expect to potentially pay more when booking in February. For low rates, April can be a great choice for travel to Syracuse. Flights to Syracuse from Missouri in April are about $365 on average during April, but can be found for as low as $198.

What airport do you fly into for flights to Syracuse from Missouri?

Located just 4.8 mi from the city center, Syracuse Hancock Intl (SYR) is the airport most travelers will use when flying to Syracuse from Missouri.

Can I find deals for flights from Missouri to Syracuse that include hotel bookings?

Yes. In addition to deals on Missouri to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Syracuse?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Syracuse.

Can I find deals for business class flights from Missouri to Syracuse?

Yes. Cheapflights offers flight deals from Missouri to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$122+ Cheap Flights from Missouri to Syracuse

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Cheap flight deals from Missouri to Syracuse

Round-trip from	$249 (United Airlines)
One-way from	$142 (Kiwi.com)
Popular in	February
Cheapest in	April
Average price	$389

From Missouri to Syracuse Hancock Intl

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One-way flight from Missouri to Syracuse Hancock Intl

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Highest demand for flights based on searches. 6% potential increase in price ($24 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from Missouri to Syracuse

Cheapest flights from Missouri to Syracuse
Explore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Wed 10/86:08 pmSTL - SYR

1 stop4h 30mAmerican Airlines

Wed 10/156:09 amSYR - STL

1 stop4h 47mAmerican Airlines

Deal found 9/10

$250

Wed 11/53:19 pmSGF - SYR

1 stop6h 29mAmerican Airlines

Tue 11/117:26 amSYR - SGF

1 stop8h 23mAmerican Airlines

Deal found 9/10

$251

Wed 11/53:35 pmSGF - SYR

1 stop7h 45mDelta

Tue 11/116:00 amSYR - SGF

2 stops10h 17mDelta

Deal found 9/10

$256

Thu 9/255:27 amSTL - SYR

1 stop4h 33mAmerican Airlines

Mon 9/295:32 amSYR - STL

1 stop5h 49mAmerican Airlines

Deal found 9/9

$259

Tue 12/96:00 amMCI - SYR

1 stop5h 18mUnited Airlines

Tue 1/68:00 amSYR - MCI

1 stop7h 27mUnited Airlines

Deal found 9/10

$259

Wed 12/1710:45 amSTL - SYR

1 stop4h 15mDelta

Tue 12/236:59 pmSYR - STL

1 stop5h 40mDelta

Deal found 9/10

$263

Thu 9/184:00 pmSTL - SYR

1 stop18h 22mFrontier

Mon 9/2212:12 pmSYR - STL

2 stops21h 54mFrontier

Deal found 9/11

$264

Wed 12/1011:36 amMCI - SYR

2 stops10h 43mUnited Airlines

Sat 1/172:45 pmSYR - MCI

2 stops8h 14mUnited Airlines

Deal found 9/9

$269

Fri 11/75:56 pmSTL - SYR

1 stop4h 27mAmerican Airlines

Sun 11/96:00 amSYR - STL

1 stop5h 28mAmerican Airlines

Deal found 9/10

$274

Thu 10/25:47 pmMCI - SYR

1 stop4h 55mUnited Airlines

Sun 10/56:15 amSYR - MCI

1 stop5h 22mUnited Airlines

Deal found 9/11

$274

Fri 10/246:52 pmSTL - SYR

1 stop4h 28mDelta

Mon 10/276:00 amSYR - STL

1 stop7h 35mDelta

Deal found 9/10

$275

Sat 12/135:12 pmMCI - SYR

1 stop5h 33mDelta

Thu 1/156:00 amSYR - MCI

1 stop4h 54mDelta

Deal found 9/10

$287

Best flights from Missouri to Syracuse
Discover carefully curated flight deals from Missouri to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2025.

Fri 10/33:23 pmSTL - SYR

1 stop5h 05mUnited Airlines

Sun 10/56:15 amSYR - STL

1 stop5h 34mUnited Airlines

Deal found 9/11

$249

Wed 10/86:08 pmSTL - SYR

1 stop4h 30mAmerican Airlines

Wed 10/156:09 amSYR - STL

1 stop4h 47mAmerican Airlines

Deal found 9/10

$250

Wed 2/1811:45 amSGF - SYR

1 stop5h 06mDelta

Sat 2/2111:55 amSYR - SGF

1 stop5h 34mDelta

Deal found 9/11

$251

Thu 9/184:00 pmSTL - SYR

1 stop18h 22mFrontier

Mon 9/2212:12 pmSYR - STL

2 stops21h 54mFrontier

Deal found 9/11

$264

Wed 11/53:19 pmSGF - SYR

1 stop6h 29mAmerican Airlines

Tue 11/117:26 amSYR - SGF

1 stop8h 23mAmerican Airlines

Deal found 9/10

$251

Wed 11/53:35 pmSGF - SYR

1 stop7h 45mDelta

Tue 11/116:00 amSYR - SGF

2 stops10h 17mDelta

Deal found 9/10

$256

Wed 12/101:30 pmMCI - SYR

1 stop8h 45mUnited Airlines

Sat 1/178:00 amSYR - MCI

1 stop7h 27mUnited Airlines

Deal found 9/9

$259

Thu 9/255:27 amSTL - SYR

1 stop4h 33mAmerican Airlines

Mon 9/295:32 amSYR - STL

1 stop5h 49mAmerican Airlines

Deal found 9/9

$259

Sat 2/285:40 pmMCI - SYR

1 stop4h 21mDelta

Tue 3/36:00 amSYR - MCI

1 stop4h 54mDelta

Deal found 9/8

$259

Tue 12/93:25 pmMCI - SYR

1 stop4h 46mUnited Airlines

Tue 1/64:57 pmSYR - MCI

1 stop6h 02mUnited Airlines

Deal found 9/10

$259

Wed 12/103:33 pmMCI - SYR

1 stop7h 20mAmerican Airlines

Sat 1/176:05 amSYR - MCI

1 stop5h 26mAmerican Airlines

Deal found 9/9

$259

Thu 12/111:40 pmMCI - SYR

1 stop8h 35mUnited Airlines

Sat 1/178:00 amSYR - MCI

2 stops9h 08mUnited Airlines

Deal found 9/9

$264

Last-minute flights from Missouri to Syracuse
Discover last-minute flight deals from Missouri to Syracuse. Data last updated September 11, 2025 and is based on user searches.

Thu 9/184:00 pmSTL - SYR

1 stop18h 22mFrontier

Mon 9/2212:12 pmSYR - STL

2 stops21h 54mFrontier

Deal found 9/11

$264

Thu 9/255:27 amSTL - SYR

1 stop4h 33mAmerican Airlines

Mon 9/295:32 amSYR - STL

1 stop5h 49mAmerican Airlines

Deal found 9/9

$259

Thu 9/253:23 pmMCI - SYR

1 stop5h 05mUnited Airlines

Mon 9/296:15 amSYR - MCI

1 stop5h 22mUnited Airlines

Deal found 9/10

$289

Thu 10/25:47 pmMCI - SYR

1 stop4h 55mUnited Airlines

Sun 10/56:15 amSYR - MCI

1 stop5h 22mUnited Airlines

Deal found 9/11

$274

Wed 10/86:08 pmSTL - SYR

1 stop4h 30mAmerican Airlines

Wed 10/156:09 amSYR - STL

1 stop4h 47mAmerican Airlines

Deal found 9/10

$250

Wed 10/85:38 pmMCI - SYR

1 stop4h 44mAmerican Airlines

Wed 10/227:42 amSYR - MCI

1 stop5h 13mAmerican Airlines

Deal found 9/9

$259

Wed 10/153:35 pmSGF - SYR

1 stop7h 45mDelta

Tue 10/216:14 amSYR - SGF

2 stops9h 36mDelta

Deal found 9/11

$290

Thu 10/235:15 amMCI - SYR

1 stop12h 12mMultiple Airlines

Sun 10/268:57 pmSYR - MCI

2 stops23h 56mMultiple Airlines

Deal found 9/11

$288

Fri 10/246:52 pmSTL - SYR

1 stop4h 28mDelta

Mon 10/276:00 amSYR - STL

1 stop7h 35mDelta

Deal found 9/10

$275

Fri 10/244:05 pmSGF - SYR

1 stop6h 24mAmerican Airlines

Sun 11/25:00 amSYR - SGF

1 stop6h 36mAmerican Airlines

Deal found 9/10

$289

Fri 10/245:40 pmSTL - SYR

1 stop4h 26mDelta

Sun 10/266:39 pmSYR - STL

1 stop6h 02mDelta

Deal found 9/10

$307

Fri 10/315:34 amMCI - SYR

2 stops8h 15mAmerican Airlines

Wed 11/56:00 amSYR - MCI

1 stop9h 06mAmerican Airlines

Deal found 9/10

$302

One-way flights from Missouri to Syracuse
Search for one-way flight options from Missouri to Syracuse. Find affordable one-way fares based on user searches. Data last updated September 11, 2025.

Thu 10/235:15 amMCI - SYR

1 stop12h 12mMultiple Airlines

Deal found 9/11

$142

Wed 10/227:02 pmMCI - SYR

2 stops15h 19mFrontier

Deal found 9/11

$146

Thu 10/2311:32 amSTL - SYR

2 stops28h 46mFrontier

Deal found 9/10

$159

Thu 10/237:52 pmSTL - SYR

3 stops44h 19mMultiple Airlines

Deal found 9/10

$164

Sun 9/2110:35 amSTL - SYR

2 stops23h 47mMultiple Airlines

Deal found 9/10

$176

Sun 9/285:15 amMCI - SYR

2 stops29h 07mMultiple Airlines

Deal found 9/11

$178

Mon 11/249:50 amSTL - SYR

2 stops22h 38mMultiple Airlines

Deal found 9/9

$180

Wed 10/221:30 pmMCI - SYR

1 stop8h 59mAmerican Airlines

Deal found 9/11

$184

Sun 9/211:52 pmSTL - SYR

1 stop25h 51mFrontier

Deal found 9/10

$191

Sat 9/275:15 amMCI - SYR

2 stops50h 07mMultiple Airlines

Deal found 9/10

$197

Thu 1/151:44 pmMCI - SYR

1 stop18h 52mMultiple Airlines

Deal found 9/10

$198

Wed 10/298:40 pmSTL - SYR

2 stops22h 27mMultiple Airlines

Deal found 9/10

$210

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Fri 10/3

3:23 pm-9:28 pm

1 stop5h 05m

Syracuse Hancock Intl

Sun 10/5

6:15 am-10:49 am

1 stop5h 34m

$249

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Wed 10/8

6:08 pm-11:38 pm

1 stop4h 30m

Syracuse Hancock Intl

Wed 10/15

6:09 am-9:56 am

1 stop4h 47m

$250

SpringfieldSyracuse

SGF - SYR

SGFSYR

Springfield-Branson

Wed 2/18

11:45 am-5:51 pm

1 stop5h 06m

Syracuse Hancock Intl

Sat 2/21

11:55 am-4:29 pm

1 stop5h 34m

$251

SpringfieldSyracuse

SGF - SYR

SGFSYR

Springfield-Branson

Wed 11/5

3:19 pm-10:48 pm

1 stop6h 29m

Syracuse Hancock Intl

Tue 11/11

7:26 am-2:49 pm

1 stop8h 23m

$251

SpringfieldSyracuse

SGF - SYR

SGFSYR

Springfield-Branson

Wed 11/5

3:35 pm-12:20 am

1 stop7h 45m

Syracuse Hancock Intl

Tue 11/11

6:00 am-3:17 pm

2 stops10h 17m

$256

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Wed 12/10

1:30 pm-11:15 pm

1 stop8h 45m

Syracuse Hancock Intl

Sat 1/17

8:00 am-2:27 pm

1 stop7h 27m

$259

St. LouisSyracuse

STL - SYR

STLSYR

Lambert-St Louis

Thu 9/25

5:27 am-11:00 am

1 stop4h 33m

Syracuse Hancock Intl

Mon 9/29

5:32 am-10:21 am

1 stop5h 49m

$259

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Sat 2/28

5:40 pm-11:01 pm

1 stop4h 21m

Syracuse Hancock Intl

Tue 3/3

6:00 am-9:54 am

1 stop4h 54m

$259

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Tue 12/9

3:25 pm-9:11 pm

1 stop4h 46m

Syracuse Hancock Intl

Tue 1/6

4:57 pm-9:59 pm

1 stop6h 02m

$259

Kansas CitySyracuse

MCI - SYR

MCISYR

Kansas City

Wed 12/10

3:33 pm-11:53 pm

1 stop7h 20m

Syracuse Hancock Intl

Sat 1/17

6:05 am-10:31 am

1 stop5h 26m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 48 results

...

Best time to book a flight from Missouri to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Syracuse

What is the cheapest month to book a flight from Missouri to Syracuse?

Currently, January is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $272). Flying from Missouri to Syracuse in July is currently the most expensive (average of $387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SYR?

When flying from Missouri to Syracuse, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

What airport do you fly into for flights to Syracuse from Missouri?
Located just 4.8 mi from the city center, Syracuse Hancock Intl (SYR) is the airport most travelers will use when flying to Syracuse from Missouri.
How long is the flight from Missouri to Syracuse?
There are many flights that can get you from Missouri to Syracuse in 4h 30m. Fly via United Airlines, American Airlines, or Delta to get the fastest option. The distance between Missouri and Syracuse is about 801 mi. This flight may include one or multiple stops.
What are the most popular routes from Missouri to Syracuse?
While some choose either Kansas City - Syracuse Hancock Intl or Springfield-Branson - Syracuse Hancock Intl, Lambert-St Louis - Syracuse Hancock Intl is the most popular route from Missouri to Syracuse.
Can I find deals for flights from Missouri to Syracuse that include hotel bookings?
Yes. In addition to deals on Missouri to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Syracuse?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Syracuse.
Can I find deals for business class flights from Missouri to Syracuse?
Yes. Cheapflights offers flight deals from Missouri to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Syracuse?
Currently, January is the cheapest month in which you can book a flight from Missouri to Syracuse (average of $272). Flying from Missouri to Syracuse in July is currently the most expensive (average of $387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Cicero

East Syracuse

Waterloo

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Top 3 airlines flying from Missouri to Syracuse

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$198	Average$384	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$236	Average$336	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$248	Average$441	FlexibilityNo cancel fee	On-time69%

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$122+ Cheap flights from Missouri to Syracuse (SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Syracuse

Keep the following information in mind while searching for Missouri to Syracuse flight deals. Data was last updated September 11, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Missouri to Syracuse

Cheapest flights from Missouri to SyracuseExplore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Explore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Syracuse that are best for you.

Best time to book a flight from Missouri to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Syracuse

What is the cheapest month to book a flight from Missouri to Syracuse?

What is the cheapest time of day to fly from MO to SYR?

Find hourly flight availability from Missouri to Syracuse. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Syracuse from Missouri?

How long is the flight from Missouri to Syracuse?

What are the most popular routes from Missouri to Syracuse?

Can I find deals for flights from Missouri to Syracuse that include hotel bookings?

How can I find direct flights from Missouri to Syracuse?

Can I find deals for business class flights from Missouri to Syracuse?

What is the cheapest month to book a flight from Missouri to Syracuse?

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Alternative routes for Missouri to Syracuse

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Top 3 airlines flying from Missouri to Syracuse

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Cheapest flights from Missouri to Syracuse
Explore the most affordable flight options available from Missouri to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.