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St. Louis

$953+ Cheap flights from Santiago (SCL) to St. Louis (STL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — STL
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheap flight deals from Santiago to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$953
(American Airlines)

Popular in

March

Cheapest in

November
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Lambert-St Louis flights.
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From Santiago Arturo Merino Benitez to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($25 potential savings vs. average RT price).
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Find flight deals from Santiago to St. Louis

Cheapest flights from Santiago to St. Louis
Explore the most affordable flight options available from Santiago to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/59:55 pmSCL - STL
2 stops22h 40mAmerican Airlines
Mon 8/251:01 pmSTL - SCL
2 stops17h 04mAmerican Airlines
Deal found 4/28$953
This eDestinos deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2311:05 pmSCL - STL
2 stops25h 31mLATAM Airlines
Mon 6/306:00 amSTL - SCL
2 stops22h 40mLATAM Airlines
Deal found 4/28$979
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/811:00 amSCL - STL
2 stops23h 41mDelta
Mon 7/146:00 amSTL - SCL
1 stop24h 00mDelta
Deal found 4/28$980
This Copa Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/72:23 amSCL - STL
2 stops32h 36mCopa Airlines
Mon 7/148:15 amSTL - SCL
2 stops19h 49mCopa Airlines
Deal found 4/28$1,844

Cheapflights Fare Finder

Customize your flight search to find flights from Santiago to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Santiago to St. Louis that are best for you.

Fly from

Santiago

Fly to

St. Louis

Route

Depart

Return

Price

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 6/5

9:55 pm-7:35 pm

2 stops22h 40m

Lambert-St Louis

Mon 8/25

1:01 pm-7:05 am

2 stops17h 04m

$953

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 6/23

11:05 pm-11:36 pm

2 stops25h 31m

Lambert-St Louis

Mon 6/30

6:00 am-5:40 am

2 stops22h 40m

$979

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 7/8

11:00 am-9:41 am

2 stops23h 41m

Lambert-St Louis

Mon 7/14

6:00 am-7:00 am

1 stop24h 00m

$980

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 7/7

2:23 am-9:59 am

2 stops32h 36m

Lambert-St Louis

Mon 7/14

8:15 am-5:04 am

2 stops19h 49m

$1,844

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Compare providers for flights from Santiago to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to St. Louis in April.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santiago-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santiago-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to St. Louis

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated April 29, 2025.
Delta
8.0
Very good
7,929 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
LATAM Airlines
7.5
Good
1,766 reviews
Delta
8.0
Very good
7,929 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.5
Good
1,410 reviews
Delta
8.0
Very good
7,929 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,929 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santiago to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santiago to St. Louis round-trip?

    According to our current data, American Airlines ($953), LATAM Airlines ($979), and Delta ($980) offers the cheapest pricing from Santiago to St. Louis. You may be able to fly from Santiago to St. Louis for 5% less than the average price by searching for these airlines.

  • Can I find deals for flights from Santiago to St. Louis that include hotel bookings?

    Yes. In addition to deals on Santiago to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to St. Louis.

  • Can I find deals for business class flights from Santiago to St. Louis?

    Yes. Cheapflights offers flight deals from Santiago to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Santiago to St. Louis (average of $311). Flying from Santiago to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Fenton
Maryland Heights
Fairview Heights
Collinsville
Wentzville
Eureka
St. Peters
Festus
Glencoe
Alton
Farmington

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Top 3 airlines flying from Santiago to St. Louis

Discover the top 3 airlines that operate flights from Santiago to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$782Average$962FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$782Average$1,120FlexibilityNo cancel feeOn-time71%
DeltaCheapest$843Average$1,019FlexibilityNo cancel feeOn-timeN/A

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