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$274+ Cheap flights from Santa Fe to St. Louis (SAF - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/28. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — STL
Jul 9 — Jul 161
Thu 7/9
Thu 7/16
1 adult, Economy
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Cheap flight deals from Santa Fe to St. Louis

Cheapest flights from Santa Fe to St. Louis
Explore the most affordable flight options available from Santa Fe to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.

This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:13 pm
SAF
-
STL
1 stop5h 46m
American Airlines
Mon 6/295:29 am
STL
-
SAF
1 stop5h 09m
American Airlines
Deal found 6/5$314
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:25 pm
SAF
-
STL
1 stop7h 25m
American Airlines
Mon 11/166:00 am
STL
-
SAF
1 stop7h 24m
American Airlines
Deal found 6/6$324
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:13 pm
SAF
-
STL
1 stop5h 46m
American Airlines
Mon 6/295:18 pm
STL
-
SAF
1 stop5h 41m
American Airlines
Deal found 6/8$334
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:13 pm
SAF
-
STL
1 stop5h 46m
American Airlines
Sun 7/55:32 am
STL
-
SAF
1 stop5h 09m
American Airlines
Deal found 6/8$364
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:35 pm
SAF
-
STL
1 stop7h 17m
American Airlines
Sun 9/205:43 am
STL
-
SAF
1 stop5h 00m
American Airlines
Deal found 6/6$403
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:21 pm
SAF
-
STL
1 stop4h 25m
United Airlines
Tue 9/15:10 am
STL
-
SAF
1 stop5h 36m
United Airlines
Deal found 6/3$431
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:13 pm
SAF
-
STL
1 stop5h 46m
American Airlines
Sun 6/145:29 am
STL
-
SAF
1 stop5h 09m
American Airlines
Deal found 6/3$450
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:45 am
SAF
-
STL
2 stops11h 40m
United Airlines
Mon 11/164:30 pm
STL
-
SAF
1 stop6h 31m
United Airlines
Deal found 6/6$488

Find flight deals from Santa Fe to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$314
(American Airlines)

One-way from

$274
(American Airlines)
Provider with most accurate pricing for Santa Fe-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Santa Fe-Lambert-St Louis flights.
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From Santa Fe to Lambert-St Louis
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One-way flight from Santa Fe to Lambert-St Louis
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Santa Fe to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sat 7/4

6:50 am-2:05 pm

1 stop6h 15m

Lambert-St Louis

Fri 7/10

5:30 am-9:41 am

1 stop5h 11m

$324

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Fri 6/26

5:13 pm-11:59 pm

1 stop5h 46m

Lambert-St Louis

Mon 6/29

5:18 pm-9:59 pm

1 stop5h 41m

$334

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Fri 9/18

12:35 pm-8:52 pm

1 stop7h 17m

Lambert-St Louis

Sun 9/20

5:43 am-9:43 am

1 stop5h 00m

$403
Quickest round-trip

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sat 8/29

3:21 pm-8:46 pm

1 stop4h 25m

Lambert-St Louis

Tue 9/1

5:10 am-9:46 am

1 stop5h 36m

$431

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Wed 11/11

10:45 am-11:25 pm

2 stops11h 40m

Lambert-St Louis

Mon 11/16

4:30 pm-10:01 pm

1 stop6h 31m

$488
Cheapest one-way

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sun 6/28

6:05 am-12:49 pm

1 stop5h 44m

$274
Quickest one-way

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Mon 6/29

6:55 am-1:12 pm

1 stop5h 17m

$274

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Tue 6/30

5:13 pm-11:59 pm

1 stop5h 46m

$274

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sun 8/9

7:10 am-2:45 pm

1 stop6h 35m

$350

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Tue 6/30

10:30 am-9:26 pm

2 stops9h 56m

$355

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/7

Showing 1-10 of 11 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Santa Fe-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Fe-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Fe-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Fe-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Fe-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Fe to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Fe to St. Louis?

    American Airlines and United Airlines can get you from Santa Fe to St. Louis in just under 4h 25m. Your travel time can differ by up to 1h 50m. There are 890 mi between Santa Fe and St. Louis. This flight may include one or multiple stops.

  • Can I find deals for flights from Santa Fe to St. Louis that include hotel bookings?

    Yes. In addition to deals on Santa Fe to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to St. Louis.

  • Can I find deals for business class flights from Santa Fe to St. Louis?

    Yes. Cheapflights offers flight deals from Santa Fe to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
O'Fallon
Edwardsville
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus

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