$264+ Cheap flights from Santa Fe to St. Louis (SAF - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/29. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — STL
Aug 2 — Aug 91
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
One-way
Cheapest flights from Santa Fe to St. LouisExplore the most affordable flight options available from Santa Fe to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2026.
Explore the most affordable flight options available from Santa Fe to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2026.
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:11 pm
SAF
- STL
1 stop6h 48m
American Airlines
Sun 11/17:29 am
STL
- SAF
1 stop6h 30m
American Airlines
Deal found 7/1![American Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:51 am
SAF
- STL
1 stop6h 02m
American Airlines
Sat 7/185:28 pm
STL
- SAF
1 stop5h 36m
American Airlines
Deal found 6/29![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:20 pm
SAF
- STL
1 stop4h 14m
United Airlines
Sat 10/318:33 am
STL
- SAF
2 stops9h 37m
United Airlines
Deal found 7/1![United Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 pm
SAF
- STL
1 stop4h 57m
United Airlines
Sun 7/195:10 am
STL
- SAF
1 stop5h 34m
United Airlines
Deal found 6/29![United Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:20 pm
SAF
- STL
1 stop4h 14m
United Airlines
Sat 10/318:33 am
STL
- SAF
2 stops9h 37m
United Airlines
Deal found 7/1![United Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am
SAF
- STL
1 stop4h 43m
United Airlines
Tue 12/84:30 pm
STL
- SAF
1 stop6h 31m
United Airlines
Deal found 7/2![United Airlines logo]()
$426
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:22 pm
SAF
- STL
2 stops7h 38m
United Airlines
Mon 8/311:36 pm
STL
- SAF
1 stop4h 35m
United Airlines
Deal found 7/1![United Airlines logo]()
$453
Best flights from Santa Fe to St. LouisDiscover carefully curated flight deals from Santa Fe to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2026.
Discover carefully curated flight deals from Santa Fe to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2026.
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:20 pm
SAF
- STL
1 stop4h 14m
United Airlines
Sat 10/318:33 am
STL
- SAF
2 stops9h 37m
United Airlines
Deal found 7/1![United Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:23 pm
SAF
- STL
1 stop5h 35m
American Airlines
Sat 7/189:44 am
STL
- SAF
2 stops10h 12m
American Airlines
Deal found 6/29![American Airlines logo]()
$515
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am
SAF
- STL
1 stop4h 43m
United Airlines
Tue 12/84:30 pm
STL
- SAF
1 stop6h 31m
United Airlines
Deal found 7/1![United Airlines logo]()
$426
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:22 pm
SAF
- STL
2 stops7h 38m
United Airlines
Mon 8/311:36 pm
STL
- SAF
1 stop4h 35m
United Airlines
Deal found 7/1![United Airlines logo]()
$453
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/131:22 pm
SAF
- STL
2 stops9h 07m
United Airlines
Sun 7/195:10 am
STL
- SAF
1 stop5h 34m
United Airlines
Deal found 6/29![United Airlines logo]()
$583
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:20 pm
SAF
- STL
2 stops6h 49m
United Airlines
Sun 11/16:00 am
STL
- SAF
2 stops12h 10m
United Airlines
Deal found 7/1![United Airlines logo]()
$741
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1410:30 am
SAF
- STL
2 stops9h 56m
United Airlines
Sat 7/187:20 am
STL
- SAF
2 stops10h 52m
United Airlines
Deal found 6/29![United Airlines logo]()
$800
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:05 am
SAF
- STL
2 stops7h 41m
United Airlines
Mon 7/206:00 am
STL
- SAF
2 stops9h 44m
United Airlines
Deal found 7/1![United Airlines logo]()
$1,027
Last-minute flights from Santa Fe to St. LouisDiscover last-minute flight deals from Santa Fe to St. Louis. Data last updated July 3, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Fe to St. Louis. Data last updated July 3, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 pm
SAF
- STL
1 stop4h 57m
United Airlines
Sun 7/195:10 am
STL
- SAF
1 stop5h 34m
United Airlines
Deal found 6/29![United Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1312:58 pm
SAF
- STL
2 stops10h 18m
American Airlines
Sun 7/199:44 am
STL
- SAF
2 stops10h 12m
American Airlines
Deal found 6/29![American Airlines logo]()
$1,012
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:51 am
SAF
- STL
1 stop6h 02m
American Airlines
Sat 7/185:28 pm
STL
- SAF
1 stop5h 36m
American Airlines
Deal found 6/29![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1410:30 am
SAF
- STL
2 stops9h 56m
United Airlines
Sat 7/187:20 am
STL
- SAF
2 stops10h 52m
United Airlines
Deal found 6/29![United Airlines logo]()
$800
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:23 pm
SAF
- STL
1 stop5h 29m
American Airlines
Mon 7/209:44 am
STL
- SAF
2 stops10h 12m
American Airlines
Deal found 7/1![American Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:05 am
SAF
- STL
2 stops7h 41m
United Airlines
Mon 7/206:00 am
STL
- SAF
2 stops9h 44m
United Airlines
Deal found 7/1![United Airlines logo]()
$1,027
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:40 am
SAF
- STL
1 stop6h 34m
American Airlines
Mon 8/315:42 am
STL
- SAF
1 stop7h 25m
American Airlines
Deal found 7/1![American Airlines logo]()
$304
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:22 pm
SAF
- STL
2 stops7h 38m
United Airlines
Mon 8/311:36 pm
STL
- SAF
1 stop4h 35m
United Airlines
Deal found 7/1![United Airlines logo]()
$453
One-way flights from Santa Fe to St. LouisSearch for one-way flight options from Santa Fe to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 3, 2026.
Search for one-way flight options from Santa Fe to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 3, 2026.
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:48 am
SAF
- STL
1 stop8h 36m
American Airlines
Deal found 7/1![American Airlines logo]()
$264
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:22 pm
SAF
- STL
2 stops8h 37m
United Airlines
Deal found 7/1![United Airlines logo]()
$274
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:22 pm
SAF
- STL
2 stops21h 40m
United Airlines
Deal found 7/1![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 pm
SAF
- STL
2 stops17h 02m
United Airlines
Deal found 7/1![United Airlines logo]()
$563
Find flight deals from Santa Fe to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $304 (American Airlines) |
One-way from | $264 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Fe to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from Santa Fe to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa FeSt. Louis
SAF - STL
SAFSTL
Santa Fe
Wed 10/28
3:20 pm-8:34 pm
1 stop4h 14m
Lambert-St Louis
Sat 10/31
8:33 am-5:10 pm
2 stops9h 37m
$361
Quickest round-trip
Santa FeSt. Louis
SAF - STL
SAFSTL
Santa Fe
Sat 12/5
7:00 am-12:43 pm
1 stop4h 43m
Lambert-St Louis
Tue 12/8
4:30 pm-10:01 pm
1 stop6h 31m
$426
Santa FeSt. Louis
SAF - STL
SAFSTL
Santa Fe
Sat 8/29
1:22 pm-10:00 pm
2 stops7h 38m
Lambert-St Louis
Mon 8/31
1:36 pm-5:11 pm
1 stop4h 35m
$453
Santa FeSt. Louis
SAF - STL
SAFSTL
Santa Fe
Tue 7/14
5:23 pm-11:58 pm
1 stop5h 35m
Lambert-St Louis
Sat 7/18
9:44 am-6:56 pm
2 stops10h 12m
$515
Santa FeSt. Louis
SAF - STL
SAFSTL
Santa Fe
Mon 7/13
1:22 pm-11:29 pm
2 stops9h 07m
Lambert-St Louis
Sun 7/19
5:10 am-9:44 am
1 stop5h 34m
$583
Santa FeSt. Louis
SAF - STL
SAFSTL
Santa Fe
Wed 10/28
3:20 pm-11:09 pm
2 stops6h 49m
Lambert-St Louis
Sun 11/1
6:00 am-5:10 pm
2 stops12h 10m
$741
Santa FeSt. Louis
SAF - STL
SAFSTL
Santa Fe
Tue 7/14
10:30 am-9:26 pm
2 stops9h 56m
Lambert-St Louis
Sat 7/18
7:20 am-5:12 pm
2 stops10h 52m
$800
Santa FeSt. Louis
SAF - STL
SAFSTL
Santa Fe
Thu 7/16
7:05 am-3:46 pm
2 stops7h 41m
Lambert-St Louis
Mon 7/20
6:00 am-2:44 pm
2 stops9h 44m
$1,027
Cheapest one-way
Quickest one-way
Santa FeSt. Louis
SAF - STL
SAFSTL
Santa Fe
Sat 8/29
10:30 am-4:34 pm
1 stop5h 04m
$264
Santa FeSt. Louis
SAF - STL
SAFSTL
Santa Fe
Mon 8/24
6:48 am-4:24 pm
1 stop8h 36m
$264
Showing 1-10 of 11 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santa Fe-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Fe-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Fe-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Fe-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Fe-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Fe to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Fe with our price prediction graph.
SAF-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 3, 2026.
See what other customers who have flown with American Airlines from Santa Fe to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Crew
7.9
Overall
7.1
Boarding
7.5
Entertainment
6.8
Food
6.4
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Comfort
7.2
Crew
7.9
Overall
7.1
Boarding
7.5
Entertainment
6.8
Food
6.4
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from Santa Fe to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Alton
Farmington
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Santa Fe and St. Louis flights
Browse other Santa Fe and St. Louis flight options. Last updated on July 3, 2026.
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Browse through other flights departing from Santa Fe. Flights are based on user searches made on Cheapflights and were last updated on July 3, 2026.
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Top airline flying from Santa Fe to St. Louis
Discover the top airline that operate flights from Santa Fe to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$319 | Average$364 | FlexibilityNo cancel fee | On-time71% |