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$240+ Cheap flights from Santa Fe to St. Louis (SAF - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — STL
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Santa Fe to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$244
(United Airlines)

One-way from

$240
(United Airlines)

Popular in

June

Cheapest in

September

Average price

$249
From Santa Fe to Lambert-St Louis
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One-way flight from Santa Fe to Lambert-St Louis
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Highest demand for flights based on searches. 15% potential increase in price ($66 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santa Fe to St. Louis

Cheapest flights from Santa Fe to St. Louis
Explore the most affordable flight options available from Santa Fe to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:59 pmSAF - STL
1 stop4h 59mUnited Airlines
Sun 10/125:15 amSTL - SAF
1 stop5h 09mUnited Airlines
Deal found 9/14$244
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/110:45 amSAF - STL
1 stop4h 47mUnited Airlines
Sun 10/55:15 amSTL - SAF
1 stop5h 09mUnited Airlines
Deal found 9/16$254
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:59 pmSAF - STL
1 stop4h 59mUnited Airlines
Sun 9/284:50 pmSTL - SAF
1 stop6h 13mUnited Airlines
Deal found 9/15$620

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Santa Fe to St. Louis that are best for you.

Fly from

Santa Fe

Fly to

St. Louis

Route

Depart

Return

Price

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Wed 10/1

6:15 am-11:52 am

1 stop4h 37m

Lambert-St Louis

Sun 10/5

5:18 am-9:33 am

1 stop5h 15m

$254

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Wed 10/1

10:45 am-4:32 pm

1 stop4h 47m

Lambert-St Louis

Sun 10/5

5:15 am-9:24 am

1 stop5h 09m

$254

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sat 2/28

10:45 am-4:34 pm

1 stop4h 49m

Lambert-St Louis

Tue 3/3

2:45 pm-8:50 pm

1 stop7h 05m

$344

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sat 2/28

7:22 pm-9:27 am

2 stops13h 05m

Lambert-St Louis

Tue 3/3

5:27 am-9:26 am

1 stop4h 59m

$376

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Fri 10/10

5:59 pm-2:27 pm

2 stops19h 28m

Lambert-St Louis

Sun 10/12

5:15 am-9:24 am

1 stop5h 09m

$479

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sun 10/19

5:59 pm-11:58 pm

1 stop4h 59m

$240

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Mon 9/22

5:18 pm-10:50 pm

1 stop4h 32m

$359

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sun 9/21

7:00 am-12:43 pm

1 stop4h 43m

$435

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Mon 9/22

7:00 am-6:23 pm

2 stops10h 23m

$445

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Best time to book a flight from Santa Fe to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to St. Louis

What is the cheapest month to book a flight from Santa Fe to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Santa Fe to St. Louis (average of $311). Flying from Santa Fe to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 16, 2025.
See what other customers who have flown with United Airlines and American Airlines from Santa Fe to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,924 reviews

Boarding

7.7

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,924 reviews
United Airlines
7.4
Good
8,924 reviews

Boarding

7.7

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,924 reviews

Boarding

7.7

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Fe to St. Louis?

    American Airlines and United Airlines can get you from Santa Fe to St. Louis in just under 4h 37m. Your travel time can differ by up to 10m. There are 890 mi between Santa Fe and St. Louis. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Santa Fe to St. Louis round-trip?

    Cheapflights users have booked flights from Santa Fe to St. Louis round-trip from $248. Another airline that can offer you cheap pricing is United Airlines. American Airlines is 32% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santa Fe to St. Louis that include hotel bookings?

    Yes. In addition to deals on Santa Fe to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to St. Louis.

  • Can I find deals for business class flights from Santa Fe to St. Louis?

    Yes. Cheapflights offers flight deals from Santa Fe to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Santa Fe to St. Louis (average of $311). Flying from Santa Fe to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Santa Fe to St. Louis

Discover the top 2 airlines that operate flights from Santa Fe to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$329FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$254Average$369FlexibilityNo cancel feeOn-time69%

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