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$274+ Cheap flights from Santa Fe to St. Louis (SAF - STL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — STL
Jan 25 — Feb 11
Sun 1/25
Sun 2/1
1 adult, Economy
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Cheap flight deals from Santa Fe to St. Louis

Best flights from Santa Fe to St. Louis
Discover carefully curated flight deals from Santa Fe to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 26, 2025.

This American Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/85:05 pmSAF - STL
1 stop4h 54mAmerican Airlines
Mon 1/123:37 pmSTL - SAF
1 stop6h 32mAmerican Airlines
Deal found 12/24$274
This United Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/710:45 amSAF - STL
2 stops11h 13mUnited Airlines
Sat 1/108:05 amSTL - SAF
2 stops9h 51mUnited Airlines
Deal found 12/24$289
This United Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/147:00 amSAF - STL
1 stop5h 14mUnited Airlines
Wed 2/182:45 pmSTL - SAF
1 stop6h 46mUnited Airlines
Deal found 12/24$369

Find flight deals from Santa Fe to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$274
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$612
Provider with most accurate pricing for Santa Fe-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Fe-Lambert-St Louis flights.
Search Deals
From Santa Fe to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($86 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
Use the filters below to find and compare flights from Santa Fe to St. Louis that are best for you.

Fly from

Santa Fe

Fly to

St. Louis

Route

Depart

Return

Price

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Thu 1/8

5:05 pm-10:59 pm

1 stop4h 54m

Lambert-St Louis

Mon 1/12

3:37 pm-9:09 pm

1 stop6h 32m

$274

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Wed 1/7

10:45 am-10:58 pm

2 stops11h 13m

Lambert-St Louis

Sat 1/10

8:05 am-4:56 pm

2 stops9h 51m

$289

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sat 2/14

7:00 am-1:14 pm

1 stop5h 14m

Lambert-St Louis

Wed 2/18

2:45 pm-8:31 pm

1 stop6h 46m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/24

Compare providers for flights from Santa Fe to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Fe to St. Louis in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Fe-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Fe-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Fe-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Fe-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Fe-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Fe to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to St. Louis

What is the cheapest month to book a flight from Santa Fe to St. Louis?

Currently, July is the cheapest month in which you can book a flight from Santa Fe to St. Louis (average of $118). Flying from Santa Fe to St. Louis in April is currently the most expensive (average of $344). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santa Fe to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated December 26, 2025.
See what other customers who have flown with United Airlines and American Airlines from Santa Fe to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,115 reviews

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,115 reviews
United Airlines
7.4
Good
9,115 reviews

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
American Airlines
7.2
Good
11,061 reviews
United Airlines
7.4
Good
9,115 reviews

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Fe to St. Louis?

    American Airlines and United Airlines can get you from Santa Fe to St. Louis in just under 4h 54m. Your travel time can differ by up to 6h 19m. There are 890 mi between Santa Fe and St. Louis. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Santa Fe to St. Louis round-trip?

    Cheapflights users have booked flights from Santa Fe to St. Louis round-trip from $244. Another airline that can offer you cheap pricing is United Airlines. American Airlines is 41% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santa Fe to St. Louis that include hotel bookings?

    Yes. In addition to deals on Santa Fe to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to St. Louis.

  • Can I find deals for business class flights from Santa Fe to St. Louis?

    Yes. Cheapflights offers flight deals from Santa Fe to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to St. Louis?

    Currently, July is the cheapest month in which you can book a flight from Santa Fe to St. Louis (average of $118). Flying from Santa Fe to St. Louis in April is currently the most expensive (average of $344). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus

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Top 2 airlines flying from Santa Fe to St. Louis

Discover the top 2 airlines that operate flights from Santa Fe to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$244Average$440FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$244Average$334FlexibilityNo cancel feeOn-time71%

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