$376+ Cheap flights from Madrid, Spain (MAD) to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — STL
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Madrid to St. LouisExplore the most affordable flight options available from Madrid to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from Madrid to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am
MAD
- STL
2 stops21h 37m
Delta
Sat 11/282:18 pm
STL
- MAD
2 stops14h 12m
Delta
Deal found 3/5![Delta logo]()
$829
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:25 am
MAD
- STL
2 stops17h 19m
Delta
Sun 4/2611:42 am
STL
- MAD
1 stop17h 33m
Delta
Deal found 3/6![Delta logo]()
$832
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
MAD
- STL
2 stops21h 44m
Delta
Sun 4/266:48 am
STL
- MAD
2 stops20h 07m
Delta
Deal found 3/5![Delta logo]()
$833
This lol.travel deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:35 pm
MAD
- STL
1 stop15h 42m
Finnair
Mon 4/135:21 pm
STL
- MAD
1 stop13h 09m
Finnair
Deal found 3/7![Finnair logo]()
$836
This Iberia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:00 pm
MAD
- STL
1 stop16h 59m
Iberia
Mon 4/138:03 pm
STL
- MAD
1 stop29h 17m
Iberia
Deal found 3/9![Iberia logo]()
$838
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
MAD
- STL
2 stops24h 14m
Delta
Wed 4/221:46 pm
STL
- MAD
2 stops15h 29m
Delta
Deal found 3/5![Delta logo]()
$842
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:55 am
MAD
- STL
1 stop14h 30m
United Airlines
Sun 4/2612:15 pm
STL
- MAD
1 stop12h 50m
United Airlines
Deal found 3/9![United Airlines logo]()
$849
This Sembo deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sembo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:55 am
MAD
- STL
1 stop14h 30m
Multiple Airlines
Fri 7/3112:10 pm
STL
- MAD
1 stop11h 40m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$850
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
MAD
- STL
2 stops18h 56m
Delta
Thu 6/115:00 pm
STL
- MAD
2 stops15h 35m
Delta
Deal found 3/6![Delta logo]()
$851
Best flights from Madrid to St. LouisDiscover carefully curated flight deals from Madrid to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from Madrid to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
MAD
- STL
2 stops24h 14m
Delta
Wed 4/221:03 pm
STL
- MAD
1 stop16h 12m
Delta
Deal found 3/5![Delta logo]()
$833
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:55 am
MAD
- STL
1 stop14h 30m
United Airlines
Sun 4/2611:15 am
STL
- MAD
2 stops14h 45m
United Airlines
Deal found 3/9![United Airlines logo]()
$849
This Finnair deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/73:55 pm
MAD
- STL
1 stop23h 59m
Multiple Airlines
Tue 4/148:54 am
STL
- MAD
1 stop16h 26m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$855
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:45 pm
MAD
- STL
1 stop28h 49m
Delta
Sun 4/266:00 am
STL
- MAD
1 stop23h 15m
Delta
Deal found 3/6![Delta logo]()
$837
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:00 am
MAD
- STL
1 stop14h 25m
United Airlines
Tue 4/710:00 am
STL
- MAD
2 stops15h 05m
United Airlines
Deal found 3/6![United Airlines logo]()
$852
Last-minute flights from Madrid to St. LouisDiscover last-minute flight deals from Madrid to St. Louis. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from Madrid to St. Louis. Data last updated March 10, 2026 and is based on user searches.
This lol.travel deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:35 pm
MAD
- STL
1 stop15h 42m
Finnair
Mon 4/135:21 pm
STL
- MAD
1 stop13h 09m
Finnair
Deal found 3/7![Finnair logo]()
$836
This Iberia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:00 pm
MAD
- STL
1 stop16h 59m
Iberia
Mon 4/138:03 pm
STL
- MAD
1 stop29h 17m
Iberia
Deal found 3/9![Iberia logo]()
$838
This Booking.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:05 pm
MAD
- STL
2 stops17h 06m
Lufthansa
Mon 4/1311:37 am
STL
- MAD
1 stop14h 23m
Lufthansa
Deal found 3/7![Lufthansa logo]()
$857
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
MAD
- STL
2 stops24h 14m
Delta
Wed 4/221:46 pm
STL
- MAD
2 stops15h 29m
Delta
Deal found 3/5![Delta logo]()
$842
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
MAD
- STL
2 stops21h 44m
Delta
Sun 4/266:48 am
STL
- MAD
2 stops20h 07m
Delta
Deal found 3/5![Delta logo]()
$833
This Iberia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:45 am
MAD
- STL
1 stop17h 32m
Iberia
Sun 4/268:03 pm
STL
- MAD
1 stop29h 17m
Iberia
Deal found 3/5![Iberia logo]()
$856
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:25 am
MAD
- STL
2 stops17h 19m
Delta
Sun 4/2611:42 am
STL
- MAD
1 stop17h 33m
Delta
Deal found 3/6![Delta logo]()
$832
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:55 am
MAD
- STL
1 stop14h 30m
United Airlines
Sun 4/2612:15 pm
STL
- MAD
1 stop12h 50m
United Airlines
Deal found 3/9![United Airlines logo]()
$849
This Booking.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:20 am
MAD
- STL
2 stops21h 51m
Lufthansa
Mon 4/2712:15 pm
STL
- MAD
1 stop12h 50m
Lufthansa
Deal found 3/10![Lufthansa logo]()
$855
One-way flights from Madrid to St. LouisSearch for one-way flight options from Madrid to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from Madrid to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:10 pm
MAD
- STL
3 stops42h 37m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:30 am
MAD
- STL
3 stops34h 25m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$406
This Gurufare deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:40 am
MAD
- STL
2 stops16h 29m
WestJet
Deal found 3/9![WestJet logo]()
$425
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/910:10 am
MAD
- STL
3 stops51h 40m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$426
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:20 am
MAD
- STL
3 stops32h 27m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$431
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:25 pm
MAD
- STL
3 stops50h 09m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$475
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:00 pm
MAD
- STL
3 stops54h 45m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$502
Find flight deals from Madrid to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $832 (Delta) |
One-way from | $376 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $834 |
Cheapflights Fare Finder
Customize your flight search to find flights from Madrid to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Madrid to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MadridSt. Louis
MAD - STL
MADSTL
Madrid Barajas
Fri 4/17
6:00 am-11:14 pm
2 stops24h 14m
Lambert-St Louis
Wed 4/22
1:03 pm-12:15 pm
1 stop16h 12m
$833
MadridSt. Louis
MAD - STL
MADSTL
Madrid Barajas
Tue 4/21
12:45 pm-10:34 am
1 stop28h 49m
Lambert-St Louis
Sun 4/26
6:00 am-12:15 pm
1 stop23h 15m
$837
Quickest round-trip
MadridSt. Louis
MAD - STL
MADSTL
Madrid Barajas
Wed 4/22
5:55 am-1:25 pm
1 stop14h 30m
Lambert-St Louis
Sun 4/26
11:15 am-9:00 am
2 stops14h 45m
$849
MadridSt. Louis
MAD - STL
MADSTL
Madrid Barajas
Fri 4/3
6:00 am-1:25 pm
1 stop14h 25m
Lambert-St Louis
Tue 4/7
10:00 am-8:05 am
2 stops15h 05m
$852
MadridSt. Louis
MAD - STL
MADSTL
Madrid Barajas
Tue 4/7
3:55 pm-8:54 am
1 stop23h 59m
Lambert-St Louis
Tue 4/14
8:54 am-8:20 am
1 stop16h 26m
$855
Cheapest one-way
MadridSt. Louis
MAD - STL
MADSTL
Madrid Barajas
Thu 5/28
8:10 pm-7:47 am
3 stops42h 37m
$376
MadridSt. Louis
MAD - STL
MADSTL
Madrid Barajas
Fri 5/29
6:20 am-7:47 am
3 stops32h 27m
$431
MadridSt. Louis
MAD - STL
MADSTL
Madrid Barajas
Wed 5/13
1:35 pm-10:19 pm
1 stop15h 44m
$535
MadridSt. Louis
MAD - STL
MADSTL
Madrid Barajas
Wed 5/13
11:45 am-10:19 pm
1 stop17h 34m
$535
MadridSt. Louis
MAD - STL
MADSTL
Madrid Barajas
Sat 6/6
6:00 pm-11:57 pm
2 stops36h 57m
$536
Showing 1-10 of 11 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Madrid-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Madrid-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Madrid-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Madrid-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Madrid to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Madrid with our price prediction graph.
MAD-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to St. Louis
What is the cheapest month to book a flight from Madrid to St. Louis?
Currently, April is the cheapest month in which you can book a flight from Madrid to St. Louis (average of $678). Flying from Madrid to St. Louis in October is currently the most expensive (average of $1,180). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Madrid to St. Louis?
Related info for your journey
Find useful and relevant information for your journey from Madrid to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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