$561+ Cheap flights from Panama City (PTY) to Spain
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Spain with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama City to SpainExplore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This Air Europa deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:30 pm -
Nonstop9h 35m
Fri 11/203:10 pm -
Nonstop10h 35m
Deal found 9/11![Air Europa logo]()
$727
This Air Europa deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:30 pm -
Nonstop9h 35m
Thu 11/193:10 pm -
Nonstop10h 35m
Deal found 9/11![Air Europa logo]()
$728
This Air Europa deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:25 pm -
Nonstop9h 50m
Wed 11/43:10 pm -
Nonstop10h 35m
Deal found 9/11![Air Europa logo]()
$729
This Air France deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:23 pm -
1 stop14h 52m
Thu 9/2412:20 pm -
1 stop14h 25m
Deal found 9/10![Air France logo]()
$730
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:35 pm -
Nonstop10h 05m
Fri 1/2212:00 pm -
Nonstop11h 05m
Deal found 9/11![Iberia logo]()
$732
This Avianca deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2010:05 am -
1 stop16h 05m
Tue 1/198:10 am -
1 stop15h 05m
Deal found 9/13![Avianca logo]()
$749
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:10 pm -
1 stop23h 15m
Mon 11/238:10 am -
1 stop23h 10m
Deal found 9/10![Avianca logo]()
$750
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:35 pm -
Nonstop10h 05m
Fri 11/2012:00 pm -
Nonstop11h 05m
Deal found 9/10![Iberia logo]()
$753
This Iberia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:35 pm -
Nonstop10h 05m
Sun 11/2212:00 pm -
Nonstop11h 05m
Deal found 9/10![Iberia logo]()
$754
This Air Europa deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:30 pm -
Nonstop9h 35m
Mon 11/163:10 pm -
Nonstop10h 35m
Deal found 9/11![Air Europa logo]()
$759
This Air Europa deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:30 pm -
Nonstop9h 35m
Sat 11/213:10 pm -
Nonstop10h 35m
Deal found 9/12![Air Europa logo]()
$760
This Air Europa deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop12h 30m
Mon 10/268:30 am -
1 stop17h 15m
Deal found 9/9![Air Europa logo]()
$779
Best flights from Panama City to SpainDiscover carefully curated flight deals from Panama City to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from Panama City to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This Air Europa deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:30 pm -
Nonstop9h 35m
Sun 11/223:10 pm -
Nonstop10h 35m
Deal found 9/12![Air Europa logo]()
$729
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/810:00 am -
1 stop16h 20m
Mon 2/1510:30 am -
2 stops39h 32m
Deal found 9/11![United Airlines logo]()
$769
This British Airways deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:35 pm -
1 stop16h 35m
Sat 11/216:00 pm -
1 stop29h 05m
Deal found 9/9![Iberia logo]()
$820
This KLM deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:46 am -
2 stops29h 24m
Tue 10/276:05 am -
2 stops20h 15m
Deal found 9/10![Multiple Airlines logo]()
$906
This Turkish Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/136:50 pm -
1 stop39h 50m
Wed 3/245:40 pm -
2 stops29h 30m
Deal found 9/13![Turkish Airlines logo]()
$910
This KLM deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:55 pm -
2 stops30h 20m
Mon 10/266:50 am -
3 stops28h 58m
Deal found 9/9![KLM logo]()
$1,009
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1010:00 am -
2 stops41h 00m
Sat 2/2010:30 am -
2 stops36h 42m
Deal found 9/12![United Airlines logo]()
$769
This Air Europa deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop12h 30m
Mon 10/268:30 am -
1 stop17h 15m
Deal found 9/9![Air Europa logo]()
$779
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/1410:00 am -
1 stop16h 20m
Tue 1/2611:00 am -
2 stops38h 38m
Deal found 9/10![United Airlines logo]()
$769
This Air Europa deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:25 pm -
1 stop16h 55m
Tue 10/2712:35 pm -
1 stop13h 10m
Deal found 9/11![Air Europa logo]()
$780
This Iberia deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:55 am -
2 stops23h 00m
Sat 11/219:35 pm -
1 stop25h 30m
Deal found 9/9![Iberia logo]()
$898
This Turkish Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/106:50 pm -
1 stop40h 25m
Sat 2/206:30 pm -
2 stops28h 40m
Deal found 9/12![Turkish Airlines logo]()
$911
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/910:00 am -
1 stop17h 30m
Fri 2/1911:15 am -
2 stops33h 30m
Deal found 9/11![United Airlines logo]()
$773
This Air Europa deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:30 pm -
1 stop16h 35m
Sat 11/219:05 pm -
1 stop28h 40m
Deal found 9/9![Air Europa logo]()
$790
This Turkish Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/306:50 pm -
1 stop34h 25m
Mon 2/85:40 pm -
2 stops29h 30m
Deal found 9/9![Turkish Airlines logo]()
$912
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:41 pm -
2 stops34h 49m
Sun 11/221:25 pm -
2 stops36h 37m
Deal found 9/13![United Airlines logo]()
$780
This Air Europa deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:25 pm -
Nonstop9h 50m
Fri 10/233:05 pm -
Nonstop10h 35m
Deal found 9/10![Air Europa logo]()
$793
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2910:00 am -
1 stop17h 30m
Mon 3/111:15 am -
2 stops33h 30m
Deal found 9/11![United Airlines logo]()
$782
This Air France deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:23 pm -
2 stops19h 12m
Sun 10/112:55 pm -
2 stops32h 55m
Deal found 9/12![Multiple Airlines logo]()
$1,170
This Air Europa deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/189:30 pm -
Nonstop9h 35m
Wed 1/273:10 pm -
Nonstop10h 35m
Deal found 9/12![Air Europa logo]()
$825
This British Airways deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:35 pm -
1 stop14h 20m
Sun 11/86:25 am -
1 stop15h 40m
Deal found 9/9![Iberia logo]()
$1,105
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/34:41 pm -
2 stops34h 49m
Fri 3/511:00 am -
2 stops36h 12m
Deal found 9/11![United Airlines logo]()
$787
This KLM deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/710:30 pm -
2 stops39h 00m
Fri 2/267:00 pm -
3 stops39h 48m
Deal found 9/13![KLM logo]()
$1,306
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:34 am -
2 stops27h 01m
Tue 11/246:50 am -
2 stops18h 40m
Deal found 9/10![Iberia logo]()
$1,109
This Turkish Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/76:50 pm -
2 stops46h 40m
Fri 2/268:30 pm -
3 stops49h 40m
Deal found 9/10![Multiple Airlines logo]()
$1,234
This Air Europa deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/309:30 pm -
1 stop16h 50m
Mon 2/812:35 pm -
1 stop13h 10m
Deal found 9/12![Air Europa logo]()
$844
This Turkish Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:00 pm -
1 stop36h 35m
Mon 1/1111:40 am -
1 stop38h 25m
Deal found 9/10![Turkish Airlines logo]()
$1,129
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:41 pm -
2 stops34h 04m
Tue 11/106:25 am -
2 stops19h 37m
Deal found 9/11![United Airlines logo]()
$797
This KLM deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:45 pm -
1 stop18h 45m
Sun 11/87:00 pm -
2 stops30h 20m
Deal found 9/10![KLM logo]()
$1,321
This Air Europa deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/269:30 pm -
1 stop14h 25m
Mon 3/87:05 am -
1 stop17h 40m
Deal found 9/11![Air Europa logo]()
$870
Last-minute flights from Panama City to SpainDiscover last-minute flight deals from Panama City to Spain. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Spain. Data last updated September 14, 2026 and is based on user searches.
This Air France deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:23 pm -
1 stop14h 52m
Tue 9/226:00 am -
1 stop17h 50m
Deal found 9/13![Multiple Airlines logo]()
$758
This Air France deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:23 pm -
1 stop14h 52m
Thu 9/2412:20 pm -
1 stop14h 25m
Deal found 9/10![Air France logo]()
$730
This Air France deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:23 pm -
1 stop14h 52m
Fri 9/256:00 am -
2 stops20h 45m
Deal found 9/10![Multiple Airlines logo]()
$762
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/119:45 am -
1 stop16h 15m
Wed 10/2110:50 am -
1 stop15h 41m
Deal found 9/9![United Airlines logo]()
$772
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:45 am -
2 stops38h 05m
Fri 10/3011:00 am -
2 stops38h 02m
Deal found 9/11![United Airlines logo]()
$771
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/189:45 am -
1 stop16h 15m
Mon 11/211:00 am -
2 stops39h 02m
Deal found 9/12![United Airlines logo]()
$767
This Air Europa deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:25 pm -
Nonstop9h 50m
Wed 11/43:10 pm -
Nonstop10h 35m
Deal found 9/11![Air Europa logo]()
$729
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:05 am -
1 stop14h 05m
Thu 11/128:10 am -
1 stop15h 05m
Deal found 9/10![Avianca logo]()
$750
This Air Europa deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:30 pm -
Nonstop9h 35m
Fri 11/63:10 pm -
Nonstop10h 35m
Deal found 9/12![Air Europa logo]()
$759
This Air Europa deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:30 pm -
Nonstop9h 35m
Sat 11/73:10 pm -
Nonstop10h 35m
Deal found 9/11![Air Europa logo]()
$761
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:30 pm -
Nonstop9h 35m
Thu 11/53:10 pm -
Nonstop10h 35m
Deal found 9/10![Air Europa logo]()
$760
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:30 am -
1 stop17h 45m
Sat 11/711:00 am -
2 stops39h 02m
Deal found 9/10![United Airlines logo]()
$768
One-way flights from Panama City to SpainSearch for one-way flight options from Panama City to Spain. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from Panama City to Spain. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This Air Europa deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:30 pm -
1 stop13h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Air Europa logo]()
$561
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:05 pm -
3 stops48h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$569
This Air Europa deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop29h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Air Europa logo]()
$570
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:50 pm -
1 stop32h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Aeromexico logo]()
$603
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:05 pm -
3 stops41h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$603
This KLM deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:45 pm -
1 stop15h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![KLM logo]()
$606
This KLM deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:55 pm -
1 stop15h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![KLM logo]()
$608
This Air France deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:55 pm -
1 stop14h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Air France logo]()
$609
This FlightHub deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:39 pm -
2 stops20h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$625
This Air France deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:24 pm -
1 stop14h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Air France logo]()
$630
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2710:25 am -
3 stops41h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$631
This KLM deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:50 pm -
1 stop21h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![KLM logo]()
$635
Find flight deals from Panama City to Spain
Keep the following information in mind while searching for Panama City to Spain flight deals. Data was last updated September 14, 2026.
Round-trip from | $702 (Expedia) |
|---|---|
One-way from | $561 (Air Europa) |
Popular in | January |
Cheapest in | May |
Average price | $941 |
Good round-trip deal | $885 or less |
Good one-way deal | $777 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from Panama City to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityBarcelona
PTY Panama City Tocumen Intl - BCN Barcelona-El Prat
PTYBCN
Panama City Tocumen Intl
Mon 10/19
8:25 pm-4:35 pm
1 stop13h 10m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$561
Panama CityBarcelona
PTY Panama City Tocumen Intl - BCN Barcelona-El Prat
PTYBCN
Panama City Tocumen Intl
Wed 10/28
9:30 pm-4:40 pm
1 stop13h 10m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$561
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Mon 10/12
9:55 pm-11:25 pm
2 stops18h 30m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$641
Panama CityBarcelona
PTY Panama City Tocumen Intl - BCN Barcelona-El Prat
PTYBCN
Panama City Tocumen Intl
Fri 10/9
9:05 pm-7:30 pm
1 stop15h 25m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$647
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Fri 10/9
9:05 pm-2:10 pm
Nonstop10h 05m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$650
Panama CityBarcelona
PTY Panama City Tocumen Intl - BCN Barcelona-El Prat
PTYBCN
Panama City Tocumen Intl
Mon 10/19
6:50 pm-6:50 pm
1 stop17h 00m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$654
Panama CityIbiza
PTY Panama City Tocumen Intl - IBZ Ibiza
PTYIBZ
Panama City Tocumen Intl
Fri 10/9
9:33 pm-8:00 pm
2 stops39h 27m
Ibiza
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$659
Panama CityIbiza
PTY Panama City Tocumen Intl - IBZ Ibiza
PTYIBZ
Panama City Tocumen Intl
Fri 10/9
9:05 pm-8:55 pm
1 stop16h 50m
Ibiza
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$665
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Fri 1/22
4:00 pm-6:05 pm
2 stops20h 05m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$670
Quickest round-trip
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Fri 1/22
9:30 pm-1:05 pm
Nonstop9h 35m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$673
Showing 1-10 of 51 resultsSorted by cheapest first
Best time to book a flight from Panama City to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Panama City with our price prediction graph.
PTY-BCN
PTY-MAD
PTY-IBZ
PTY-BIO
PTY-AGP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Spain
PTY-ES0
PTY-BCN
PTY-MAD
PTY-IBZ
PTY-BIO
What is the cheapest month to book a flight from Panama City to Spain?
Currently, February is the cheapest month in which you can book a flight from Panama City to Spain (average of $766). Flying from Panama City to Spain in July is currently the most expensive (average of $973). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to ES?
Find hourly flight availability from Panama City to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 14, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Spain as you normally would.
Weekly flight availability from Panama City to Spain
Explore weekly flight availability from Panama City to Spain. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 14, 2026.
The most flights from PTY to ES0 are scheduled on a Friday (10 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (5 on average).
How often are flights from Panama City to Spain delayed?
About 12% of weekly flights between Panama City and Spain have experienced delays in the past year, with the average delay time being 146 minutes.
What is the most punctual flight time for Panama City to Spain flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Spain flights?
Over the last year, Air Europa have had the lowest number of delays on this route, with just 9% of flights being delayed.
How far ahead should I book a flight from Panama City to Spain?
Booking 90 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Spain. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Spain
Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated September 14, 2026.
Get a feel of what it's like to fly with Air France,United Airlines, andIberia from Panama City to Spain by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.0
Overall
7.5
Crew
8.2
Comfort
7.4
Food
7.1
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Entertainment
7.0
Overall
7.5
Crew
8.2
Comfort
7.4
Food
7.1
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Entertainment
7.0
Overall
7.5
Crew
8.2
Comfort
7.4
Food
7.1
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Entertainment
7.0
Overall
7.5
Crew
8.2
Comfort
7.4
Food
7.1
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Entertainment
7.0
Overall
7.5
Crew
8.2
Comfort
7.4
Food
7.1
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Entertainment
7.0
Overall
7.5
Crew
8.2
Comfort
7.4
Food
7.1
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Related info for your journey
Find useful and relevant information for your journey from Panama City to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama City to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Spain by cabin class
Find flights from Panama City to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Spain flights
Browse other Panama City and Spain flight options. Last updated on September 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 8 airlines flying from Panama City to Spain
Discover the top 8 airlines that operate flights from Panama City to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$567 | Average$845 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$618 | Average$1,154 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$644 | Average$900 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$658 | Average$1,103 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$666 | Average$916 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$667 | Average$969 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$728 | Average$1,347 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$763 | Average$869 | FlexibilityNo cancel fee | On-time69% |