$495+ Cheap flights from Panama City (PTY) to Spain
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
Mar 6 — Mar 131
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama City to SpainExplore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
Explore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
This Air France deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:27 pm
PTY
- MAD
1 stop14h 48m
Air France
Sun 6/76:00 am
MAD
- PTY
1 stop20h 45m
Air France
Deal found 2/4![Air France logo]()
$644
This Air France deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/42:27 pm
PTY
- MAD
1 stop14h 48m
Multiple Airlines
Mon 5/115:20 pm
MAD
- PTY
1 stop30h 30m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$645
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:50 pm
PTY
- MAD
1 stop34h 20m
Multiple Airlines
Tue 6/3012:20 pm
MAD
- PTY
1 stop14h 25m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$648
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:50 pm
PTY
- MAD
1 stop17h 45m
Multiple Airlines
Thu 6/255:45 pm
MAD
- PTY
1 stop33h 00m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$661
This Air France deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:27 pm
PTY
- MAD
2 stops19h 18m
Multiple Airlines
Fri 5/155:20 pm
MAD
- PTY
1 stop30h 30m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$664
This Air France deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:27 pm
PTY
- MAD
1 stop14h 48m
Air France
Tue 5/126:00 am
MAD
- PTY
2 stops17h 50m
Air France
Deal found 2/2![Air France logo]()
$666
This KLM deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1810:05 pm
PTY
- MAD
1 stop33h 35m
Multiple Airlines
Wed 2/256:00 am
MAD
- PTY
1 stop20h 10m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$667
This KLM deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:50 pm
PTY
- MAD
1 stop35h 50m
Multiple Airlines
Tue 6/1612:20 pm
MAD
- PTY
1 stop14h 25m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$668
This KLM deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:50 pm
PTY
- MAD
1 stop35h 50m
KLM
Wed 5/271:05 pm
MAD
- PTY
1 stop34h 45m
KLM
Deal found 2/2![KLM logo]()
$669
This KLM deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:55 pm
PTY
- AGP
1 stop17h 40m
Multiple Airlines
Wed 6/310:40 am
AGP
- PTY
1 stop37h 10m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$675
This Air France deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:15 pm
PTY
- MAD
1 stop36h 00m
Multiple Airlines
Mon 3/161:05 pm
MAD
- PTY
1 stop33h 25m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$677
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:45 pm
PTY
- BCN
1 stop15h 45m
Multiple Airlines
Wed 2/186:00 am
BCN
- PTY
1 stop20h 10m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$682
Best flights from Panama City to SpainDiscover carefully curated flight deals from Panama City to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
Discover carefully curated flight deals from Panama City to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
This Air France deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:55 pm
PTY
- AGP
1 stop17h 40m
Air France
Wed 6/36:00 am
AGP
- PTY
2 stops17h 50m
Air France
Deal found 2/4![Air France logo]()
$696
This Turkish Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/169:45 pm
PTY
- BCN
1 stop37h 20m
Turkish Airlines
Sun 6/712:10 pm
BCN
- PTY
1 stop39h 15m
Turkish Airlines
Deal found 2/2![Turkish Airlines logo]()
$702
This Air Europa deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:25 pm
PTY
- MAD
Nonstop9h 50m
Air Europa
Wed 4/293:05 pm
MAD
- PTY
Nonstop10h 35m
Air Europa
Deal found 2/2![Air Europa logo]()
$727
This KLM deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:55 pm
PTY
- AGP
2 stops17h 15m
Multiple Airlines
Wed 6/36:00 am
AGP
- PTY
2 stops17h 50m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$728
This KLM deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:50 pm
PTY
- AGP
1 stop21h 10m
KLM
Mon 6/810:55 pm
AGP
- PTY
2 stops27h 50m
KLM
Deal found 2/4![KLM logo]()
$788
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/310:55 pm
PTY
- BCN
2 stops26h 25m
United Airlines
Mon 4/2012:00 pm
BCN
- PTY
2 stops33h 14m
United Airlines
Deal found 2/3![United Airlines logo]()
$844
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:55 pm
PTY
- VLC
2 stops32h 10m
Avianca
Mon 4/279:40 am
VLC
- PTY
2 stops30h 35m
Avianca
Deal found 2/1![Avianca logo]()
$989
This Iberia deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/249:05 pm
PTY
- SDR
1 stop29h 25m
Iberia
Thu 7/25:40 pm
SDR
- PTY
1 stop32h 55m
Iberia
Deal found 2/3![Iberia logo]()
$1,114
This Turkish Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:20 pm
PTY
- BCN
1 stop29h 25m
Turkish Airlines
Wed 4/227:35 am
BCN
- PTY
1 stop19h 50m
Turkish Airlines
Deal found 2/2![Turkish Airlines logo]()
$702
This FlightHub deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:25 pm
PTY
- AGP
1 stop16h 55m
Air Europa
Mon 6/85:05 pm
AGP
- PTY
1 stop32h 35m
Air Europa
Deal found 2/3![Air Europa logo]()
$735
This KLM deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:50 pm
PTY
- AGP
1 stop17h 25m
Multiple Airlines
Mon 4/277:30 pm
AGP
- PTY
2 stops28h 20m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$778
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:45 pm
PTY
- VLC
1 stop32h 20m
KLM
Wed 3/186:55 pm
VLC
- PTY
1 stop27h 35m
KLM
Deal found 2/3![KLM logo]()
$810
This Turkish Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:20 pm
PTY
- BCN
1 stop18h 00m
Turkish Airlines
Mon 5/47:35 am
BCN
- PTY
1 stop19h 50m
Turkish Airlines
Deal found 2/3![Turkish Airlines logo]()
$740
This Air Europa deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:25 pm
PTY
- VGO
1 stop12h 35m
Air Europa
Thu 4/2312:35 pm
VGO
- PTY
1 stop13h 05m
Air Europa
Deal found 2/3![Air Europa logo]()
$743
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:55 pm
PTY
- BCN
2 stops31h 20m
United Airlines
Wed 4/223:15 pm
BCN
- PTY
2 stops35h 16m
United Airlines
Deal found 2/3![United Airlines logo]()
$844
This KLM deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:55 pm
PTY
- BIO
1 stop28h 55m
Multiple Airlines
Mon 5/187:10 am
BIO
- PTY
2 stops16h 40m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$807
This Turkish Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:05 pm
PTY
- BCN
1 stop31h 40m
Turkish Airlines
Sat 5/97:35 am
BCN
- PTY
1 stop19h 50m
Turkish Airlines
Deal found 2/2![Turkish Airlines logo]()
$744
This Air Europa deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:25 pm
PTY
- MAD
Nonstop9h 50m
Air Europa
Wed 5/133:05 pm
MAD
- PTY
Nonstop10h 35m
Air Europa
Deal found 2/3![Air Europa logo]()
$759
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:55 pm
PTY
- BCN
2 stops26h 25m
United Airlines
Mon 4/2011:15 am
BCN
- PTY
2 stops39h 16m
United Airlines
Deal found 2/3![United Airlines logo]()
$844
This Avianca deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/202:55 am
PTY
- SCQ
2 stops23h 50m
Avianca
Sat 3/289:45 pm
SCQ
- PTY
2 stops22h 30m
Avianca
Deal found 2/4![Avianca logo]()
$995
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:45 pm
PTY
- VLC
1 stop19h 30m
KLM
Sat 2/2810:40 am
VLC
- PTY
1 stop35h 50m
KLM
Deal found 2/3![KLM logo]()
$905
This Turkish Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:20 pm
PTY
- BCN
1 stop29h 25m
Turkish Airlines
Sun 4/197:05 pm
BCN
- PTY
1 stop32h 20m
Turkish Airlines
Deal found 2/1![Turkish Airlines logo]()
$749
This Air Europa deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:25 pm
PTY
- IBZ
1 stop34h 45m
Air Europa
Wed 5/273:00 pm
IBZ
- PTY
1 stop34h 40m
Air Europa
Deal found 2/3![Air Europa logo]()
$762
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/203:30 pm
PTY
- MAD
2 stops34h 30m
United Airlines
Wed 5/2711:15 am
MAD
- PTY
2 stops38h 22m
United Airlines
Deal found 2/4![United Airlines logo]()
$849
This KLM deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/312:20 pm
PTY
- VLC
2 stops19h 30m
Multiple Airlines
Mon 8/313:30 pm
VLC
- PTY
1 stop32h 20m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$882
This Turkish Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:45 pm
PTY
- MAD
1 stop33h 35m
Turkish Airlines
Tue 3/242:25 pm
MAD
- PTY
1 stop35h 25m
Turkish Airlines
Deal found 2/2![Turkish Airlines logo]()
$755
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:45 am
PTY
- MAD
1 stop16h 15m
United Airlines
Sat 5/911:15 am
MAD
- PTY
2 stops33h 59m
United Airlines
Deal found 2/3![United Airlines logo]()
$849
This Trip.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:20 pm
PTY
- SCQ
1 stop32h 25m
Iberia
Sat 3/289:45 pm
SCQ
- PTY
1 stop28h 15m
Iberia
Deal found 2/4![Iberia logo]()
$1,145
This FlightHub deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:25 pm
PTY
- AGP
1 stop12h 50m
Air Europa
Sun 6/148:35 am
AGP
- PTY
1 stop17h 05m
Air Europa
Deal found 2/2![Air Europa logo]()
$789
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/79:55 pm
PTY
- SVQ
1 stop18h 30m
Multiple Airlines
Wed 4/2210:05 am
SVQ
- PTY
1 stop37h 45m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$890
Last-minute flights from Panama City to SpainDiscover last-minute flight deals from Panama City to Spain. Data last updated February 4, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Spain. Data last updated February 4, 2026 and is based on user searches.
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:45 pm
PTY
- BCN
1 stop15h 45m
Multiple Airlines
Wed 2/186:00 am
BCN
- PTY
1 stop20h 10m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$682
This KLM deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:45 pm
PTY
- BCN
1 stop15h 45m
KLM
Wed 2/185:25 pm
BCN
- PTY
1 stop29h 05m
KLM
Deal found 2/4![KLM logo]()
$685
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:45 pm
PTY
- MAD
1 stop15h 20m
KLM
Fri 2/207:05 am
MAD
- PTY
1 stop15h 25m
KLM
Deal found 2/3![KLM logo]()
$709
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:45 pm
PTY
- BCN
1 stop15h 45m
KLM
Sun 2/151:00 pm
BCN
- PTY
1 stop33h 30m
KLM
Deal found 2/3![KLM logo]()
$748
This KLM deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:45 pm
PTY
- MAD
1 stop15h 20m
Multiple Airlines
Sat 2/146:45 pm
MAD
- PTY
1 stop31h 25m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$741
This KLM deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1110:05 pm
PTY
- MAD
1 stop30h 10m
Multiple Airlines
Wed 2/256:00 am
MAD
- PTY
1 stop20h 10m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$693
This KLM deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1110:05 pm
PTY
- MAD
1 stop30h 10m
KLM
Tue 2/176:00 am
MAD
- PTY
1 stop16h 30m
KLM
Deal found 2/2![KLM logo]()
$702
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1110:05 pm
PTY
- MAD
1 stop30h 10m
KLM
Wed 2/257:05 am
MAD
- PTY
1 stop18h 50m
KLM
Deal found 2/3![KLM logo]()
$717
This KLM deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1110:05 pm
PTY
- MAD
1 stop30h 10m
KLM
Sat 2/287:05 am
MAD
- PTY
1 stop15h 25m
KLM
Deal found 2/4![KLM logo]()
$754
This Turkish Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/169:45 pm
PTY
- BCN
1 stop37h 20m
Turkish Airlines
Sun 6/712:10 pm
BCN
- PTY
1 stop39h 15m
Turkish Airlines
Deal found 2/2![Turkish Airlines logo]()
$702
This Air France deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1710:20 pm
PTY
- BCN
1 stop18h 35m
Air France
Tue 3/179:55 am
BCN
- PTY
1 stop16h 15m
Air France
Deal found 2/3![Air France logo]()
$712
This Turkish Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:45 pm
PTY
- BCN
1 stop31h 00m
Turkish Airlines
Tue 2/2412:05 pm
BCN
- PTY
2 stops35h 00m
Turkish Airlines
Deal found 2/2![Turkish Airlines logo]()
$741
One-way flights from Panama City to SpainSearch for one-way flight options from Panama City to Spain. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
Search for one-way flight options from Panama City to Spain. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/62:55 am
PTY
- MAD
3 stops35h 25m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$495
This Avianca deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:50 pm
PTY
- MAD
1 stop13h 35m
Avianca
Deal found 2/2![Avianca logo]()
$515
This Avianca deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:45 am
PTY
- MAD
1 stop17h 05m
Avianca
Deal found 2/3![Avianca logo]()
$519
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/222:55 am
PTY
- MAD
3 stops35h 25m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$533
This FlightHub deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/62:55 am
PTY
- MAD
1 stop19h 40m
Avianca
Deal found 2/3![Avianca logo]()
$539
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:50 pm
PTY
- MAD
1 stop13h 35m
Avianca
Deal found 2/3![Avianca logo]()
$541
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:50 pm
PTY
- BCN
3 stops36h 30m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$541
This deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/139:45 am
PTY
- MAD
1 stop12h 50m
Avianca
Deal found 2/2![Avianca logo]()
$545
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:45 am
PTY
- MAD
3 stops26h 20m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$556
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1010:25 am
PTY
- SVQ
3 stops46h 40m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$556
This Avianca deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/102:55 pm
PTY
- SVQ
2 stops35h 35m
Avianca
Deal found 2/3![Avianca logo]()
$562
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:55 pm
PTY
- BCN
3 stops33h 40m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$573
Find flight deals from Panama City to Spain
Keep the following information in mind while searching for Panama City to Spain flight deals. Data was last updated February 4, 2026.
Round-trip from | $644 (Air France) |
|---|---|
One-way from | $495 (Mytrip) |
Popular in | January |
Cheapest in | October |
Average price | $800 |
Good round-trip deal | $726 or less |
Good one-way deal | $811 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Panama City to Spain that are best for you.
Fly from
Panama City
Fly to
Spain
Route
Depart
Return
Price
Panama CityMálaga
PTY - AGP
PTYAGP
Panama City Tocumen Intl
Tue 5/26
9:55 pm-10:35 pm
1 stop17h 40m
Malaga
Wed 6/3
6:00 am-4:50 pm
2 stops17h 50m
$696
Panama CityBarcelona
PTY - BCN
PTYBCN
Panama City Tocumen Intl
Mon 2/16
9:45 pm-5:05 pm
1 stop37h 20m
Barcelona-El Prat
Sun 6/7
12:10 pm-8:25 pm
1 stop39h 15m
$702
Panama CityBarcelona
PTY - BCN
PTYBCN
Panama City Tocumen Intl
Wed 4/15
10:20 pm-10:45 am
1 stop29h 25m
Barcelona-El Prat
Wed 4/22
7:35 am-8:25 pm
1 stop19h 50m
$702
Panama CityMadrid
PTY - MAD
PTYMAD
Panama City Tocumen Intl
Wed 4/22
8:25 pm-1:15 pm
Nonstop9h 50m
Madrid Barajas
Wed 4/29
3:05 pm-6:40 pm
Nonstop10h 35m
$727
Panama CityMálaga
PTY - AGP
PTYAGP
Panama City Tocumen Intl
Tue 5/26
9:55 pm-10:10 pm
2 stops17h 15m
Malaga
Wed 6/3
6:00 am-4:50 pm
2 stops17h 50m
$728
Panama CityMálaga
PTY - AGP
PTYAGP
Panama City Tocumen Intl
Wed 6/3
8:25 pm-8:20 pm
1 stop16h 55m
Malaga
Mon 6/8
5:05 pm-6:40 pm
1 stop32h 35m
$735
Panama CityBarcelona
PTY - BCN
PTYBCN
Panama City Tocumen Intl
Wed 4/22
10:20 pm-11:20 pm
1 stop18h 00m
Barcelona-El Prat
Mon 5/4
7:35 am-8:25 pm
1 stop19h 50m
$740
Panama CityVigo
PTY - VGO
PTYVGO
Panama City Tocumen Intl
Sun 4/19
8:25 pm-4:00 pm
1 stop12h 35m
Vigo
Thu 4/23
12:35 pm-6:40 pm
1 stop13h 05m
$743
Panama CityBarcelona
PTY - BCN
PTYBCN
Panama City Tocumen Intl
Tue 4/28
8:05 pm-10:45 am
1 stop31h 40m
Barcelona-El Prat
Sat 5/9
7:35 am-8:25 pm
1 stop19h 50m
$744
Panama CityBarcelona
PTY - BCN
PTYBCN
Panama City Tocumen Intl
Wed 4/1
10:20 pm-10:45 am
1 stop29h 25m
Barcelona-El Prat
Sun 4/19
7:05 pm-8:25 pm
1 stop32h 20m
$749
Showing 1-10 of 60 results
Best time to book a flight from Panama City to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Panama City with our price prediction graph.
PTY-BCN
PTY-MAD
PTY-AGP
PTY-VLC
PTY-SDR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Spain
PTY-ES0
PTY-BCN
PTY-MAD
PTY-AGP
PTY-VLC
What is the cheapest month to book a flight from Panama City to Spain?
Currently, November is the cheapest month in which you can book a flight from Panama City to Spain (average of $155). Flying from Panama City to Spain in December is currently the most expensive (average of $702). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to ES?
Find hourly flight availability from Panama City to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 4, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Spain as you normally would.
Weekly flight availability from Panama City to Spain
Explore weekly flight availability from Panama City to Spain. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 4, 2026.
The most flights from PTY to ES0 are scheduled on a Monday (10 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (5 on average).
How often are flights from Panama City to Spain delayed?
About 12% of weekly flights between Panama City and Spain have experienced delays in the past year, with the average delay time being 140 minutes.
What is the most punctual flight time for Panama City to Spain flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Sunday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Spain flights?
Over the last year, Pascan have had the lowest number of delays on this route, with just 6% of flights being delayed.
Reviews of airlines servicing Spain
Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated February 4, 2026.
Get a feel of what it's like to fly with Air France, Turkish Airlines, and Iberia from Panama City to Spain by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.1
Entertainment
7.0
Boarding
7.4
Comfort
7.3
Overall
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Food
7.0
Crew
8.1
Entertainment
7.0
Boarding
7.4
Comfort
7.3
Overall
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Food
7.0
Crew
8.1
Entertainment
7.0
Boarding
7.4
Comfort
7.3
Overall
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Food
7.0
Crew
8.1
Entertainment
7.0
Boarding
7.4
Comfort
7.3
Overall
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Food
7.0
Crew
8.1
Entertainment
7.0
Boarding
7.4
Comfort
7.3
Overall
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Food
7.0
Crew
8.1
Entertainment
7.0
Boarding
7.4
Comfort
7.3
Overall
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Related info for your journey
Find useful and relevant information for your journey from Panama City to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama City to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Spain by cabin class
Find flights from Panama City to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Spain flights
Browse other Panama City and Spain flight options. Last updated on February 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 7 airlines flying from Panama City to Spain
Discover the top 7 airlines that operate flights from Panama City to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$623 | Average$1,031 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$654 | Average$1,080 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$666 | Average$895 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$670 | Average$886 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$695 | Average$841 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$698 | Average$773 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$722 | Average$1,269 | FlexibilityNo cancel fee | On-time70% |