$623+ Cheap flights from Panama City (PTY) to Spain
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
Sep 16 — Sep 231
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Spain with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama City to SpainExplore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
Explore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
This Avianca deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/292:55 am -
1 stop14h 25m
Thu 2/46:35 am -
1 stop16h 20m
Deal found 8/12![Avianca logo]()
$750
This Avianca deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:50 pm -
1 stop19h 15m
Wed 3/315:20 pm -
1 stop22h 55m
Deal found 8/13![Avianca logo]()
$751
This Avianca deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:50 pm -
1 stop19h 15m
Tue 4/132:20 am -
1 stop21h 40m
Deal found 8/12![Avianca logo]()
$752
This Air France deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:23 pm -
1 stop14h 52m
Wed 9/236:00 am -
1 stop17h 50m
Deal found 8/13![Multiple Airlines logo]()
$757
This Air France deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:23 pm -
1 stop14h 52m
Thu 9/176:00 am -
2 stops20h 45m
Deal found 8/16![Multiple Airlines logo]()
$761
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/189:45 am -
1 stop16h 15m
Sat 11/2111:00 am -
2 stops33h 45m
Deal found 8/16![United Airlines logo]()
$763
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:00 am -
1 stop16h 20m
Fri 12/410:30 am -
2 stops39h 32m
Deal found 8/14![United Airlines logo]()
$763
This KLM deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:55 pm -
2 stops18h 30m
Tue 10/1310:05 am -
1 stop16h 40m
Deal found 8/13![Multiple Airlines logo]()
$766
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3010:00 am -
1 stop16h 20m
Wed 12/301:35 pm -
2 stops45h 35m
Deal found 8/14![United Airlines logo]()
$767
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am -
1 stop16h 15m
Tue 10/2010:50 am -
1 stop15h 41m
Deal found 8/15![United Airlines logo]()
$768
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:45 am -
1 stop16h 15m
Wed 10/710:50 am -
1 stop15h 41m
Deal found 8/16![United Airlines logo]()
$770
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:55 am -
2 stops19h 20m
Tue 11/101:25 pm -
2 stops36h 37m
Deal found 8/15![United Airlines logo]()
$771
Best flights from Panama City to SpainDiscover carefully curated flight deals from Panama City to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
Discover carefully curated flight deals from Panama City to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:55 am -
2 stops41h 25m
Tue 12/110:30 am -
2 stops34h 15m
Deal found 8/12![United Airlines logo]()
$763
This Air Europa deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:25 pm -
1 stop13h 10m
Sat 10/108:30 pm -
1 stop29h 10m
Deal found 8/12![Air Europa logo]()
$851
This Turkish Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/310:00 pm -
1 stop19h 50m
Mon 2/812:20 pm -
2 stops34h 50m
Deal found 8/16![Turkish Airlines logo]()
$868
This Turkish Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3010:00 pm -
1 stop31h 15m
Mon 2/81:50 pm -
3 stops33h 20m
Deal found 8/14![Multiple Airlines logo]()
$999
This Iberia deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:16 pm -
2 stops36h 09m
Sun 10/116:15 pm -
2 stops49h 47m
Deal found 8/14![Iberia logo]()
$1,243
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/283:30 pm -
2 stops34h 30m
Thu 10/1510:50 am -
1 stop15h 41m
Deal found 8/12![United Airlines logo]()
$768
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/119:45 am -
1 stop16h 15m
Wed 10/2110:50 am -
1 stop15h 41m
Deal found 8/14![United Airlines logo]()
$772
This Air Europa deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:25 pm -
1 stop12h 30m
Thu 10/2212:45 pm -
1 stop12h 55m
Deal found 8/14![Air Europa logo]()
$861
This Turkish Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:20 pm -
1 stop17h 55m
Sun 10/1812:10 pm -
1 stop39h 15m
Deal found 8/14![Turkish Airlines logo]()
$868
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/34:41 pm -
2 stops34h 34m
Fri 3/511:15 am -
1 stop23h 55m
Deal found 8/12![United Airlines logo]()
$777
This Turkish Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/26:50 pm -
1 stop34h 05m
Fri 2/126:30 pm -
1 stop31h 35m
Deal found 8/16![Turkish Airlines logo]()
$869
This Air Europa deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:25 pm -
1 stop12h 50m
Wed 9/2312:30 pm -
1 stop13h 10m
Deal found 8/16![Air Europa logo]()
$893
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2910:00 am -
1 stop17h 15m
Sat 2/2711:15 am -
2 stops33h 30m
Deal found 8/12![United Airlines logo]()
$777
This KLM deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:55 pm -
1 stop18h 15m
Mon 10/196:30 am -
2 stops20h 15m
Deal found 8/16![Multiple Airlines logo]()
$1,050
This Air Europa deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:25 pm -
1 stop12h 30m
Sun 9/2712:45 pm -
1 stop12h 55m
Deal found 8/13![Air Europa logo]()
$894
This Turkish Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3010:00 pm -
1 stop36h 40m
Mon 2/85:40 pm -
1 stop32h 25m
Deal found 8/15![Turkish Airlines logo]()
$911
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2910:00 am -
1 stop17h 15m
Mon 3/111:15 am -
2 stops33h 30m
Deal found 8/14![United Airlines logo]()
$777
This Turkish Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2110:20 pm -
2 stops34h 35m
Wed 9/236:25 pm -
2 stops31h 05m
Deal found 8/13![Multiple Airlines logo]()
$1,067
This Air Europa deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:25 pm -
1 stop12h 30m
Thu 9/248:20 am -
1 stop17h 20m
Deal found 8/13![Air Europa logo]()
$894
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:45 am -
1 stop16h 15m
Fri 10/3011:00 am -
2 stops32h 45m
Deal found 8/16![United Airlines logo]()
$777
This Trip.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:00 pm -
1 stop30h 40m
Thu 12/35:35 pm -
1 stop32h 30m
Deal found 8/13![Turkish Airlines logo]()
$941
This British Airways deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:35 pm -
1 stop32h 45m
Sun 11/86:50 am -
1 stop15h 15m
Deal found 8/14![Iberia logo]()
$1,304
This Air Europa deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:25 pm -
1 stop16h 50m
Fri 9/2512:45 pm -
1 stop12h 55m
Deal found 8/13![Air Europa logo]()
$894
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:30 pm -
2 stops33h 50m
Mon 9/2111:15 am -
2 stops33h 59m
Deal found 8/14![United Airlines logo]()
$777
This Turkish Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:20 pm -
1 stop29h 15m
Mon 10/1211:35 am -
2 stops37h 50m
Deal found 8/14![Turkish Airlines logo]()
$955
This Air Europa deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:25 pm -
1 stop16h 50m
Thu 9/2412:45 pm -
1 stop12h 55m
Deal found 8/13![Air Europa logo]()
$894
This Air Europa deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:44 pm -
2 stops18h 21m
Sun 10/112:55 pm -
1 stop34h 45m
Deal found 8/15![Multiple Airlines logo]()
$1,199
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:30 am -
2 stops39h 30m
Fri 11/611:15 am -
2 stops33h 30m
Deal found 8/15![United Airlines logo]()
$780
This Turkish Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/1510:00 pm -
1 stop36h 35m
Sun 1/315:35 pm -
2 stops29h 35m
Deal found 8/16![Turkish Airlines logo]()
$1,000
This Expedia deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:35 pm -
1 stop25h 30m
Fri 1/86:25 am -
1 stop15h 40m
Deal found 8/15![Iberia logo]()
$1,478
Last-minute flights from Panama City to SpainDiscover last-minute flight deals from Panama City to Spain. Data last updated August 17, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Spain. Data last updated August 17, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:50 pm -
1 stop19h 15m
Wed 3/315:20 pm -
1 stop22h 55m
Deal found 8/13![Avianca logo]()
$751
This Avianca deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:50 pm -
1 stop19h 15m
Tue 4/132:20 am -
1 stop21h 40m
Deal found 8/12![Avianca logo]()
$752
This Air France deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:23 pm -
1 stop14h 52m
Thu 9/176:00 am -
2 stops20h 45m
Deal found 8/16![Multiple Airlines logo]()
$761
This Air France deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:23 pm -
1 stop14h 52m
Wed 9/236:00 am -
1 stop17h 50m
Deal found 8/13![Multiple Airlines logo]()
$757
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:00 am -
2 stops20h 15m
Wed 10/711:15 am -
2 stops39h 16m
Deal found 8/13![United Airlines logo]()
$763
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:30 pm -
2 stops34h 30m
Mon 9/2810:50 am -
1 stop15h 41m
Deal found 8/17![United Airlines logo]()
$771
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:00 am -
2 stops20h 15m
Sat 10/31:15 pm -
2 stops37h 16m
Deal found 8/13![United Airlines logo]()
$771
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:30 pm -
2 stops33h 35m
Wed 9/2310:50 am -
1 stop15h 41m
Deal found 8/14![United Airlines logo]()
$777
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:45 am -
1 stop16h 15m
Tue 10/61:30 pm -
2 stops37h 01m
Deal found 8/15![United Airlines logo]()
$776
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:45 am -
1 stop16h 15m
Thu 10/810:50 am -
1 stop15h 41m
Deal found 8/15![United Airlines logo]()
$768
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:45 am -
1 stop16h 15m
Wed 10/710:50 am -
1 stop15h 41m
Deal found 8/16![United Airlines logo]()
$770
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:45 am -
1 stop16h 15m
Sat 10/1710:50 am -
1 stop15h 41m
Deal found 8/12![United Airlines logo]()
$772
One-way flights from Panama City to SpainSearch for one-way flight options from Panama City to Spain. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
Search for one-way flight options from Panama City to Spain. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
This Mytrip deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:10 am -
2 stops16h 35m
Deal found 8/12![Multiple Airlines logo]()
$623
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:35 pm -
3 stops36h 05m
Deal found 8/12![Multiple Airlines logo]()
$624
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:30 am -
3 stops21h 05m
Deal found 8/13![Multiple Airlines logo]()
$633
This Air France deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/122:24 pm -
1 stop14h 51m
Deal found 8/12![Air France logo]()
$642
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:25 am -
3 stops35h 35m
Deal found 8/12![Multiple Airlines logo]()
$645
This British Airways deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:05 pm -
Nonstop10h 05m
Deal found 8/16![Iberia logo]()
$648
This Iberia deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:05 pm -
1 stop19h 15m
Deal found 8/13![Iberia logo]()
$665
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1210:25 am -
3 stops50h 15m
Deal found 8/14![Multiple Airlines logo]()
$685
This SmartFares deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:25 pm -
1 stop16h 55m
Deal found 8/15![Air Europa logo]()
$687
This Air Europa deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:30 pm -
1 stop13h 10m
Deal found 8/14![Air Europa logo]()
$689
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:11 am -
3 stops48h 59m
Deal found 8/15![Multiple Airlines logo]()
$695
This Air Europa deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:25 pm -
1 stop17h 05m
Deal found 8/13![Air Europa logo]()
$704
Find flight deals from Panama City to Spain
Keep the following information in mind while searching for Panama City to Spain flight deals. Data was last updated August 17, 2026.
Round-trip from | $750 (Avianca) |
|---|---|
One-way from | $623 (Mytrip) |
Popular in | January |
Cheapest in | May |
Average price | $972 |
Good round-trip deal | $903 or less |
Good one-way deal | $688 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from Panama City to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityBarcelona
PTY Panama City Tocumen Intl - BCN Barcelona-El Prat
PTYBCN
Panama City Tocumen Intl
Sat 11/21
8:55 am-8:20 am
2 stops41h 25m
Barcelona-El Prat
Tue 12/1
10:30 am-2:45 pm
2 stops34h 15m
$763
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Mon 9/28
3:30 pm-9:00 am
2 stops34h 30m
Madrid Barajas
Thu 10/15
10:50 am-7:31 pm
1 stop15h 41m
$768
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Sun 10/11
9:45 am-9:00 am
1 stop16h 15m
Madrid Barajas
Wed 10/21
10:50 am-7:31 pm
1 stop15h 41m
$772
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Wed 2/3
4:41 pm-9:15 am
2 stops34h 34m
Madrid Barajas
Fri 3/5
11:15 am-5:10 am
1 stop23h 55m
$777
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Fri 1/29
10:00 am-9:15 am
1 stop17h 15m
Madrid Barajas
Sat 2/27
11:15 am-2:45 pm
2 stops33h 30m
$777
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Fri 1/29
10:00 am-9:15 am
1 stop17h 15m
Madrid Barajas
Mon 3/1
11:15 am-2:45 pm
2 stops33h 30m
$777
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Wed 10/14
9:45 am-9:00 am
1 stop16h 15m
Madrid Barajas
Fri 10/30
11:00 am-1:45 pm
2 stops32h 45m
$777
Panama CityBarcelona
PTY Panama City Tocumen Intl - BCN Barcelona-El Prat
PTYBCN
Panama City Tocumen Intl
Fri 9/11
3:30 pm-8:20 am
2 stops33h 50m
Barcelona-El Prat
Mon 9/21
11:15 am-2:14 pm
2 stops33h 59m
$777
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Sun 10/25
9:30 am-7:00 am
2 stops39h 30m
Madrid Barajas
Fri 11/6
11:15 am-2:45 pm
2 stops33h 30m
$780
Panama CityBarcelona
PTY Panama City Tocumen Intl - BCN Barcelona-El Prat
PTYBCN
Panama City Tocumen Intl
Wed 10/7
8:25 pm-4:35 pm
1 stop13h 10m
Barcelona-El Prat
Sat 10/10
8:30 pm-6:40 pm
1 stop29h 10m
$851
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Panama City to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Panama City with our price prediction graph.
PTY-BCN
PTY-AGP
PTY-IBZ
PTY-MAD
PTY-BIO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Spain
PTY-ES0
PTY-BCN
PTY-AGP
PTY-IBZ
PTY-MAD
What is the cheapest month to book a flight from Panama City to Spain?
Currently, February is the cheapest month in which you can book a flight from Panama City to Spain (average of $764). Flying from Panama City to Spain in July is currently the most expensive (average of $973). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to ES?
Find hourly flight availability from Panama City to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 17, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Spain as you normally would.
Weekly flight availability from Panama City to Spain
Explore weekly flight availability from Panama City to Spain. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 17, 2026.
The most flights from PTY to ES0 are scheduled on a Monday (10 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (4 on average).
How often are flights from Panama City to Spain delayed?
About 12% of weekly flights between Panama City and Spain have experienced delays in the past year, with the average delay time being 148 minutes.
What is the most punctual flight time for Panama City to Spain flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Spain flights?
Over the last year, Air Europa have had the lowest number of delays on this route, with just 9% of flights being delayed.
How far ahead should I book a flight from Panama City to Spain?
Booking 90 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Spain. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Spain
Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated August 17, 2026.
Get a feel of what it's like to fly with Air France,United Airlines, andAir Europa from Panama City to Spain by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.2
Overall
7.5
Entertainment
7.0
Boarding
7.5
Food
7.1
Comfort
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Crew
8.2
Overall
7.5
Entertainment
7.0
Boarding
7.5
Food
7.1
Comfort
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Crew
8.2
Overall
7.5
Entertainment
7.0
Boarding
7.5
Food
7.1
Comfort
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Crew
8.2
Overall
7.5
Entertainment
7.0
Boarding
7.5
Food
7.1
Comfort
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Crew
8.2
Overall
7.5
Entertainment
7.0
Boarding
7.5
Food
7.1
Comfort
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Crew
8.2
Overall
7.5
Entertainment
7.0
Boarding
7.5
Food
7.1
Comfort
7.4
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Related info for your journey
Find useful and relevant information for your journey from Panama City to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama City to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Spain by cabin class
Find flights from Panama City to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Spain flights
Browse other Panama City and Spain flight options. Last updated on August 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 8 airlines flying from Panama City to Spain
Discover the top 8 airlines that operate flights from Panama City to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$508 | Average$1,317 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$618 | Average$1,189 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$644 | Average$900 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$658 | Average$1,103 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$666 | Average$914 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$671 | Average$977 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$698 | Average$784 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$763 | Average$860 | FlexibilityNo cancel fee | On-time69% |