$504+ Cheap flights from Panama City (PTY) to Spain
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
abr. 6 — abr. 131
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Panama City to Spain with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Spain
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to SpainExplore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 7, 2026.
Explore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 7, 2026.
This KLM deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/46:45 pm
PTY
- MAD
1 stop33h 30m
KLM
lun. 3/161:05 pm
MAD
- PTY
1 stop33h 25m
KLM
Deal found 3/2![KLM logo]()
$645
This Air France deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/272:27 pm
PTY
- MAD
1 stop14h 48m
Multiple Airlines
mié. 5/136:00 am
MAD
- PTY
1 stop17h 50m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$647
This Air France deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/302:27 pm
PTY
- MAD
1 stop14h 48m
Air France
mar. 5/1912:20 pm
MAD
- PTY
1 stop14h 25m
Air France
Deal found 3/2![Air France logo]()
$657
This Air France deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/292:27 pm
PTY
- MAD
1 stop14h 48m
Multiple Airlines
dom. 5/176:00 am
MAD
- PTY
1 stop17h 50m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$658
This Air France deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/272:27 pm
PTY
- MAD
1 stop14h 48m
Air France
sáb. 5/235:45 pm
MAD
- PTY
1 stop33h 00m
Air France
Deal found 3/7![Air France logo]()
$660
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/106:50 pm
PTY
- MAD
1 stop31h 40m
KLM
sáb. 5/161:05 pm
MAD
- PTY
1 stop34h 45m
KLM
Deal found 3/4![KLM logo]()
$661
This Air France deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/1010:10 pm
PTY
- MAD
1 stop28h 00m
Multiple Airlines
vie. 5/1510:25 am
MAD
- PTY
1 stop37h 25m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$664
This KLM deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/46:45 pm
PTY
- MAD
1 stop33h 30m
Multiple Airlines
mié. 3/186:00 am
MAD
- PTY
2 stops16h 30m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$665
This Air France deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/272:27 pm
PTY
- MAD
1 stop14h 48m
Air France
mar. 5/126:00 am
MAD
- PTY
2 stops17h 50m
Air France
Deal found 3/4![Air France logo]()
$668
This Air France deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/272:27 pm
PTY
- MAD
1 stop14h 48m
Air France
mié. 5/136:00 am
MAD
- PTY
2 stops17h 50m
Air France
Deal found 3/3![Air France logo]()
$669
This Air France deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/282:27 pm
PTY
- MAD
1 stop14h 48m
Air France
sáb. 5/305:45 pm
MAD
- PTY
1 stop33h 35m
Air France
Deal found 3/3![Air France logo]()
$671
This KLM deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/266:50 pm
PTY
- AGP
1 stop20h 20m
KLM
mié. 6/312:55 pm
AGP
- PTY
1 stop34h 55m
KLM
Deal found 3/5![KLM logo]()
$673
Best flights from Panama City to SpainDiscover carefully curated flight deals from Panama City to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated marzo 7, 2026.
Discover carefully curated flight deals from Panama City to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated marzo 7, 2026.
This KLM deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/266:50 pm
PTY
- AGP
1 stop20h 20m
KLM
mié. 6/312:55 pm
AGP
- PTY
1 stop34h 55m
KLM
Deal found 3/5![KLM logo]()
$673
This KLM deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/176:50 pm
PTY
- BCN
1 stop30h 55m
Multiple Airlines
lun. 6/86:10 am
BCN
- PTY
1 stop20h 35m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$709
This Air Europa deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/238:25 pm
PTY
- IBZ
1 stop34h 40m
Air Europa
mié. 5/272:55 pm
IBZ
- PTY
1 stop34h 45m
Air Europa
Deal found 3/2![Air Europa logo]()
$735
This Turkish Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/810:20 pm
PTY
- BIO
1 stop29h 50m
Turkish Airlines
mar. 4/1412:10 pm
BIO
- PTY
2 stops37h 15m
Turkish Airlines
Deal found 3/4![Turkish Airlines logo]()
$829
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/127:55 am
PTY
- MAD
2 stops41h 10m
United Airlines
vie. 4/2411:15 am
MAD
- PTY
2 stops38h 22m
United Airlines
Deal found 3/2![United Airlines logo]()
$849
This Iberia deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/151:27 pm
PTY
- SDR
2 stops20h 33m
Iberia
sáb. 8/159:35 pm
SDR
- PTY
1 stop29h 00m
Iberia
Deal found 3/7![Iberia logo]()
$1,004
This FlightHub deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/65:55 pm
PTY
- SCQ
2 stops36h 10m
Avianca
dom. 7/199:45 pm
SCQ
- PTY
2 stops34h 20m
Avianca
Deal found 3/4![Avianca logo]()
$1,256
This KLM deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/206:50 pm
PTY
- SVQ
1 stop18h 45m
Multiple Airlines
lun. 4/276:30 am
SVQ
- PTY
1 stop20h 15m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$713
This KLM deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/206:50 pm
PTY
- SVQ
1 stop18h 45m
KLM
lun. 4/276:30 am
SVQ
- PTY
2 stops17h 20m
KLM
Deal found 3/6![KLM logo]()
$734
This Air Europa deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/38:25 pm
PTY
- AGP
1 stop19h 35m
Air Europa
lun. 6/812:35 pm
AGP
- PTY
1 stop13h 05m
Air Europa
Deal found 3/3![Air Europa logo]()
$746
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/269:55 pm
PTY
- AGP
1 stop17h 40m
Multiple Airlines
mié. 6/310:40 am
AGP
- PTY
1 stop37h 10m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$743
This Air Europa deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/38:25 pm
PTY
- VLC
1 stop12h 50m
Air Europa
mié. 5/612:35 pm
VLC
- PTY
1 stop13h 05m
Air Europa
Deal found 3/4![Air Europa logo]()
$750
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/77:55 am
PTY
- MAD
2 stops41h 10m
United Airlines
jue. 6/411:15 am
MAD
- PTY
2 stops35h 57m
United Airlines
Deal found 3/2![United Airlines logo]()
$849
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/316:50 pm
PTY
- VLC
1 stop30h 35m
KLM
jue. 4/304:00 pm
VLC
- PTY
1 stop31h 50m
KLM
Deal found 3/4![KLM logo]()
$810
This Air Europa deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/98:25 pm
PTY
- SVQ
1 stop17h 05m
Air Europa
sáb. 6/139:15 pm
SVQ
- PTY
1 stop28h 25m
Air Europa
Deal found 3/4![Air Europa logo]()
$756
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/289:45 am
PTY
- BCN
1 stop16h 15m
United Airlines
sáb. 5/912:15 pm
BCN
- PTY
2 stops38h 16m
United Airlines
Deal found 3/2![United Airlines logo]()
$852
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/302:28 pm
PTY
- VLC
2 stops18h 47m
Multiple Airlines
jue. 4/308:45 pm
VLC
- PTY
1 stop27h 05m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$789
This KLM deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/316:50 pm
PTY
- VLC
1 stop30h 35m
KLM
mar. 4/79:20 pm
VLC
- PTY
1 stop26h 30m
KLM
Deal found 3/3![KLM logo]()
$851
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/19:45 am
PTY
- BCN
1 stop16h 15m
United Airlines
vie. 5/1512:15 pm
BCN
- PTY
2 stops38h 16m
United Airlines
Deal found 3/2![United Airlines logo]()
$852
This Air Europa deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/218:25 pm
PTY
- BCN
1 stop13h 10m
Air Europa
sáb. 5/3011:50 am
BCN
- PTY
1 stop13h 50m
Air Europa
Deal found 3/7![Air Europa logo]()
$787
This Turkish Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/98:05 pm
PTY
- SVQ
1 stop38h 30m
Turkish Airlines
sáb. 6/1311:35 am
SVQ
- PTY
2 stops37h 50m
Turkish Airlines
Deal found 3/3![Turkish Airlines logo]()
$1,057
This Turkish Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/2010:20 pm
PTY
- BIO
1 stop36h 00m
Multiple Airlines
dom. 4/2612:45 pm
BIO
- PTY
2 stops38h 40m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$838
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/229:45 am
PTY
- MAD
1 stop16h 15m
United Airlines
lun. 5/412:45 pm
MAD
- PTY
2 stops37h 46m
United Airlines
Deal found 3/7![United Airlines logo]()
$856
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/316:50 pm
PTY
- VLC
1 stop30h 35m
KLM
lun. 5/46:35 am
VLC
- PTY
2 stops20h 10m
KLM
Deal found 3/4![KLM logo]()
$858
This Iberia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/249:05 pm
PTY
- SDR
1 stop29h 25m
Iberia
jue. 7/25:40 pm
SDR
- PTY
1 stop32h 55m
Iberia
Deal found 3/5![Iberia logo]()
$1,160
This Air Europa deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/168:25 pm
PTY
- BCN
1 stop13h 10m
Air Europa
vie. 6/268:30 pm
BCN
- PTY
1 stop29h 10m
Air Europa
Deal found 3/2![Air Europa logo]()
$799
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/216:50 pm
PTY
- BCN
1 stop20h 55m
Multiple Airlines
sáb. 5/306:10 pm
BCN
- PTY
1 stop33h 10m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$855
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/2010:55 pm
PTY
- MAD
2 stops24h 55m
United Airlines
mié. 5/2010:50 am
MAD
- PTY
1 stop15h 41m
United Airlines
Deal found 3/2![United Airlines logo]()
$857
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/209:55 pm
PTY
- BIO
2 stops17h 50m
KLM
dom. 4/2612:00 pm
BIO
- PTY
1 stop35h 50m
KLM
Deal found 3/4![KLM logo]()
$879
This Air Europa deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 6/78:25 pm
PTY
- TFN
1 stop14h 30m
Air Europa
jue. 6/119:55 am
TFN
- PTY
1 stop14h 45m
Air Europa
Deal found 3/3![Air Europa logo]()
$829
Last-minute flights from Panama City to SpainDiscover last-minute flight deals from Panama City to Spain. Data last updated marzo 7, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Spain. Data last updated marzo 7, 2026 and is based on user searches.
This Air France deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/172:27 pm
PTY
- MAD
1 stop14h 48m
Multiple Airlines
sáb. 4/258:30 pm
MAD
- PTY
1 stop27h 20m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$685
This Air France deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/202:27 pm
PTY
- MAD
1 stop14h 48m
Multiple Airlines
sáb. 4/258:30 pm
MAD
- PTY
1 stop27h 20m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$676
This Air France deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/272:27 pm
PTY
- MAD
1 stop14h 48m
Multiple Airlines
sáb. 5/238:30 pm
MAD
- PTY
1 stop27h 20m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$647
This Air France deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/272:27 pm
PTY
- MAD
1 stop14h 48m
Multiple Airlines
mié. 5/136:00 am
MAD
- PTY
1 stop17h 50m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$648
This Air France deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/272:27 pm
PTY
- MAD
1 stop14h 48m
Air France
sáb. 5/235:45 pm
MAD
- PTY
1 stop33h 00m
Air France
Deal found 3/7![Air France logo]()
$660
This Air France deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/272:27 pm
PTY
- MAD
1 stop14h 48m
Air France
mar. 5/126:00 am
MAD
- PTY
2 stops17h 50m
Air France
Deal found 3/4![Air France logo]()
$668
This Air France deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/272:27 pm
PTY
- MAD
1 stop14h 48m
Air France
mié. 5/136:00 am
MAD
- PTY
2 stops17h 50m
Air France
Deal found 3/3![Air France logo]()
$669
This Air France deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/282:27 pm
PTY
- MAD
1 stop14h 48m
Air France
sáb. 5/305:45 pm
MAD
- PTY
1 stop33h 35m
Air France
Deal found 3/3![Air France logo]()
$671
This Air France deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/282:27 pm
PTY
- BCN
1 stop15h 23m
Air France
sáb. 5/912:20 pm
BCN
- PTY
1 stop14h 25m
Air France
Deal found 3/6![Air France logo]()
$710
This Air France deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/292:27 pm
PTY
- MAD
1 stop14h 48m
Multiple Airlines
dom. 5/176:00 am
MAD
- PTY
1 stop17h 50m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$658
This Air France deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/302:27 pm
PTY
- MAD
1 stop14h 48m
Air France
mar. 5/1912:20 pm
MAD
- PTY
1 stop14h 25m
Air France
Deal found 3/2![Air France logo]()
$657
This Air France deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/302:27 pm
PTY
- MAD
1 stop14h 48m
Air France
mié. 5/66:00 am
MAD
- PTY
2 stops17h 50m
Air France
Deal found 3/5![Air France logo]()
$677
One-way flights from Panama City to SpainSearch for one-way flight options from Panama City to Spain. Find affordable one-way fares based on user searches. Data last updated marzo 7, 2026.
Search for one-way flight options from Panama City to Spain. Find affordable one-way fares based on user searches. Data last updated marzo 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 4/1811:25 am
PTY
- MAD
1 stop21h 00m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$504
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/85:30 am
PTY
- MAD
3 stops30h 40m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 4/2511:25 am
PTY
- MAD
1 stop21h 00m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$528
This Avianca deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/1110:10 am
PTY
- MAD
1 stop15h 55m
Avianca
Deal found 3/2![Avianca logo]()
$539
This Avianca deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/25:55 pm
PTY
- MAD
1 stop23h 25m
Avianca
Deal found 3/4![Avianca logo]()
$540
This Mytrip deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/159:45 am
PTY
- MAD
3 stops28h 35m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$544
This Avianca deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/211:25 am
PTY
- MAD
2 stops29h 55m
Avianca
Deal found 3/4![Avianca logo]()
$549
This Avianca deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/1611:25 am
PTY
- MAD
2 stops29h 55m
Avianca
Deal found 3/4![Avianca logo]()
$553
This FlightHub deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/173:05 am
PTY
- MAD
1 stop14h 15m
Avianca
Deal found 3/4![Avianca logo]()
$560
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/179:33 pm
PTY
- BCN
3 stops39h 22m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$580
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/169:33 pm
PTY
- BCN
1 stop32h 27m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$596
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/157:50 pm
PTY
- AGP
3 stops39h 40m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$626
Find flight deals from Panama City to Spain
Keep the following information in mind while searching for Panama City to Spain flight deals. Data was last updated marzo 7, 2026.
Round-trip from | $647 (Air France) |
|---|---|
One-way from | $504 (Kiwi.com) |
Popular in | January |
Cheapest in | October |
Average price | $864 |
Good round-trip deal | $758 or less |
Good one-way deal | $636 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 7, 2026.
Use the filters below to find and compare flights from Panama City to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityMálaga
PTY - AGP
PTYAGP
Panama City Tocumen Intl
mar. 5/26
6:50 pm-10:10 pm
1 stop20h 20m
Malaga
mié. 6/3
12:55 pm-4:50 pm
1 stop34h 55m
$673
Panama CityBarcelona
PTY - BCN
PTYBCN
Panama City Tocumen Intl
dom. 5/17
6:50 pm-8:45 am
1 stop30h 55m
Barcelona-El Prat
lun. 6/8
6:10 am-7:45 pm
1 stop20h 35m
$709
Panama CitySeville
PTY - SVQ
PTYSVQ
Panama City Tocumen Intl
lun. 4/20
6:50 pm-8:35 pm
1 stop18h 45m
Sevilla
lun. 4/27
6:30 am-7:45 pm
1 stop20h 15m
$713
Panama CitySeville
PTY - SVQ
PTYSVQ
Panama City Tocumen Intl
lun. 4/20
6:50 pm-8:35 pm
1 stop18h 45m
Sevilla
lun. 4/27
6:30 am-4:50 pm
2 stops17h 20m
$734
Panama CityIbiza
PTY - IBZ
PTYIBZ
Panama City Tocumen Intl
sáb. 5/23
8:25 pm-2:05 pm
1 stop34h 40m
Ibiza
mié. 5/27
2:55 pm-6:40 pm
1 stop34h 45m
$735
Panama CityMálaga
PTY - AGP
PTYAGP
Panama City Tocumen Intl
mar. 5/26
9:55 pm-10:35 pm
1 stop17h 40m
Malaga
mié. 6/3
10:40 am-4:50 pm
1 stop37h 10m
$743
Panama CityMálaga
PTY - AGP
PTYAGP
Panama City Tocumen Intl
mié. 6/3
8:25 pm-11:00 pm
1 stop19h 35m
Malaga
lun. 6/8
12:35 pm-6:40 pm
1 stop13h 05m
$746
Quickest round-trip
Panama CityValencia
PTY - VLC
PTYVLC
Panama City Tocumen Intl
dom. 5/3
8:25 pm-4:15 pm
1 stop12h 50m
Valencia
mié. 5/6
12:35 pm-6:40 pm
1 stop13h 05m
$750
Panama CitySeville
PTY - SVQ
PTYSVQ
Panama City Tocumen Intl
mar. 6/9
8:25 pm-8:30 pm
1 stop17h 05m
Sevilla
sáb. 6/13
9:15 pm-6:40 pm
1 stop28h 25m
$756
Panama CityBarcelona
PTY - BCN
PTYBCN
Panama City Tocumen Intl
jue. 5/21
8:25 pm-4:35 pm
1 stop13h 10m
Barcelona-El Prat
sáb. 5/30
11:50 am-6:40 pm
1 stop13h 50m
$787
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Panama City to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Panama City with our price prediction graph.
PTY-MAD
PTY-BCN
PTY-VLC
PTY-AGP
PTY-IBZ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Spain
PTY-ES0
PTY-MAD
PTY-BCN
PTY-VLC
PTY-AGP
What is the cheapest month to book a flight from Panama City to Spain?
Currently, November is the cheapest month in which you can book a flight from Panama City to Spain (average of $155). Flying from Panama City to Spain in December is currently the most expensive (average of $703). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to ES?
Find hourly flight availability from Panama City to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated marzo 7, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Spain as you normally would.
How often are flights from Panama City to Spain delayed?
About 12% of weekly flights between Panama City and Spain have experienced delays in the past year, with the average delay time being 139 minutes.
What is the most punctual flight time for Panama City to Spain flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Sunday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Spain flights?
Over the last year, Air Europa have had the lowest number of delays on this route, with just 11% of flights being delayed.
Reviews of airlines servicing Spain
Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated marzo 7, 2026.
Get a feel of what it's like to fly with Air France, Turkish Airlines, and Iberia from Panama City to Spain by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.4
Comfort
7.3
Overall
7.4
Food
7.0
Entertainment
7.0
Crew
8.1
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Boarding
7.4
Comfort
7.3
Overall
7.4
Food
7.0
Entertainment
7.0
Crew
8.1
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Boarding
7.4
Comfort
7.3
Overall
7.4
Food
7.0
Entertainment
7.0
Crew
8.1
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Boarding
7.4
Comfort
7.3
Overall
7.4
Food
7.0
Entertainment
7.0
Crew
8.1
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Boarding
7.4
Comfort
7.3
Overall
7.4
Food
7.0
Entertainment
7.0
Crew
8.1
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Boarding
7.4
Comfort
7.3
Overall
7.4
Food
7.0
Entertainment
7.0
Crew
8.1
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Related info for your journey
Find useful and relevant information for your journey from Panama City to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top regions
Alternative routes for Panama City to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Spain by cabin class
Find flights from Panama City to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Spain flights
Browse other Panama City and Spain flight options. Last updated on marzo 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 7 airlines flying from Panama City to Spain
Discover the top 7 airlines that operate flights from Panama City to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$623 | Average$1,077 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$652 | Average$1,097 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$666 | Average$905 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$674 | Average$909 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$685 | Average$807 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$698 | Average$763 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$722 | Average$1,269 | FlexibilityNo cancel fee | On-time70% |