$512+ Cheap flights from Panama City (PTY) to Spain
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
Nov 14 — Nov 211
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Spain with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama City to SpainExplore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 15, 2026.
Explore the most affordable flight options available from Panama City to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 15, 2026.
This Avianca deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/202:30 am -
1 stop23h 40m
Thu 1/288:10 am -
1 stop23h 10m
Deal found 10/10![Avianca logo]()
$750
This Air France deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:30 pm -
1 stop18h 35m
Fri 11/206:00 am -
1 stop20h 20m
Deal found 10/13![Air France logo]()
$753
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:00 am -
1 stop16h 20m
Fri 12/410:30 am -
2 stops39h 32m
Deal found 10/13![United Airlines logo]()
$763
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:41 pm -
2 stops38h 34m
Sun 11/223:10 pm -
2 stops34h 52m
Deal found 10/11![United Airlines logo]()
$764
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2011:55 pm -
1 stop26h 25m
Sat 1/161:35 pm -
2 stops36h 27m
Deal found 10/15![United Airlines logo]()
$766
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:00 am -
2 stops39h 45m
Sat 11/2111:00 am -
2 stops39h 02m
Deal found 10/13![United Airlines logo]()
$768
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:55 pm -
1 stop27h 35m
Sat 1/161:25 pm -
2 stops36h 37m
Deal found 10/13![United Airlines logo]()
$771
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:00 am -
1 stop17h 30m
Tue 12/81:25 pm -
2 stops31h 20m
Deal found 10/14![United Airlines logo]()
$775
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:00 am -
1 stop17h 30m
Mon 12/711:15 am -
2 stops33h 30m
Deal found 10/14![United Airlines logo]()
$777
This Air France deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:30 pm -
1 stop14h 40m
Wed 11/186:00 am -
1 stop20h 20m
Deal found 10/12![Air France logo]()
$778
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:41 pm -
2 stops33h 04m
Thu 12/1011:15 am -
2 stops33h 30m
Deal found 10/14![United Airlines logo]()
$781
This Avianca deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/282:30 am -
1 stop23h 40m
Sat 1/168:10 am -
1 stop15h 05m
Deal found 10/11![Avianca logo]()
$782
Best flights from Panama City to SpainDiscover carefully curated flight deals from Panama City to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 15, 2026.
Discover carefully curated flight deals from Panama City to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 15, 2026.
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2110:00 am -
1 stop16h 20m
Sat 1/161:35 pm -
2 stops36h 27m
Deal found 10/15![United Airlines logo]()
$766
This Gotogate deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:30 pm -
1 stop12h 45m
Tue 11/179:10 pm -
1 stop28h 35m
Deal found 10/13![Air Europa logo]()
$861
This KLM deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:45 pm -
1 stop18h 40m
Fri 11/206:05 am -
1 stop20h 15m
Deal found 10/12![Multiple Airlines logo]()
$876
This Turkish Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:00 pm -
1 stop36h 10m
Wed 1/205:40 pm -
2 stops29h 30m
Deal found 10/14![Turkish Airlines logo]()
$901
This KLM deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:45 pm -
1 stop15h 20m
Sun 2/148:55 pm -
1 stop25h 35m
Deal found 10/14![KLM logo]()
$921
This Iberia deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:13 pm -
2 stops21h 17m
Fri 11/61:25 pm -
2 stops30h 48m
Deal found 10/14![Iberia logo]()
$1,132
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/304:41 pm -
2 stops33h 04m
Sat 1/161:25 pm -
2 stops36h 37m
Deal found 10/13![United Airlines logo]()
$780
This Air Europa deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:30 pm -
1 stop12h 45m
Wed 11/188:40 am -
1 stop17h 05m
Deal found 10/13![Air Europa logo]()
$862
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2711:55 pm -
1 stop26h 25m
Sun 1/2411:00 am -
2 stops33h 45m
Deal found 10/13![United Airlines logo]()
$817
This Turkish Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:00 pm -
1 stop31h 15m
Wed 1/202:55 pm -
3 stops32h 15m
Deal found 10/14![Multiple Airlines logo]()
$914
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:00 am -
1 stop16h 20m
Fri 12/410:30 am -
2 stops39h 32m
Deal found 10/10![United Airlines logo]()
$819
This Turkish Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2810:00 pm -
1 stop31h 15m
Mon 12/145:40 pm -
2 stops29h 30m
Deal found 10/13![Turkish Airlines logo]()
$1,031
This Air Europa deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:30 pm -
1 stop19h 40m
Fri 11/2010:00 am -
1 stop14h 45m
Deal found 10/10![Air Europa logo]()
$944
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:00 am -
2 stops28h 15m
Mon 12/711:15 am -
2 stops33h 30m
Deal found 10/10![United Airlines logo]()
$820
This Travelocity deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:13 pm -
2 stops26h 22m
Fri 11/201:25 pm -
2 stops31h 09m
Deal found 10/12![Iberia logo]()
$1,136
This KLM deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1710:30 pm -
2 stops18h 55m
Sat 1/166:00 am -
3 stops29h 48m
Deal found 10/10![KLM logo]()
$1,151
This KLM deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1710:30 pm -
1 stop18h 55m
Sat 1/166:00 am -
3 stops29h 48m
Deal found 10/10![Multiple Airlines logo]()
$1,071
This Air Europa deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:30 pm -
1 stop12h 50m
Wed 12/3012:35 pm -
1 stop13h 10m
Deal found 10/15![Air Europa logo]()
$989
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:00 am -
1 stop17h 30m
Sun 12/1311:00 am -
2 stops39h 02m
Deal found 10/14![United Airlines logo]()
$823
This Turkish Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:00 pm -
1 stop30h 55m
Wed 1/136:25 pm -
2 stops28h 45m
Deal found 10/11![Turkish Airlines logo]()
$1,128
This Iberia deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:55 am -
2 stops33h 55m
Fri 11/209:30 pm -
2 stops28h 05m
Deal found 10/10![Iberia logo]()
$1,139
This KLM deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/196:45 pm -
1 stop22h 40m
Sat 1/166:00 am -
3 stops29h 48m
Deal found 10/11![KLM logo]()
$1,210
This Air Europa deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/229:30 pm -
1 stop16h 50m
Thu 11/2612:35 pm -
1 stop13h 10m
Deal found 10/14![Air Europa logo]()
$1,002
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:41 pm -
2 stops57h 04m
Sat 12/1211:15 am -
2 stops33h 30m
Deal found 10/10![United Airlines logo]()
$834
This Turkish Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:50 pm -
2 stops36h 35m
Fri 1/155:40 pm -
1 stop32h 25m
Deal found 10/12![Multiple Airlines logo]()
$1,144
This Turkish Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:00 pm -
1 stop37h 25m
Sun 1/36:25 pm -
1 stop31h 40m
Deal found 10/14![Turkish Airlines logo]()
$1,175
This Air Europa deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:30 pm -
1 stop18h 25m
Sun 11/229:55 am -
1 stop14h 50m
Deal found 10/12![Air Europa logo]()
$1,039
This SmartFares deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/304:33 pm -
2 stops36h 12m
Fri 1/158:30 pm -
2 stops45h 56m
Deal found 10/12![Iberia logo]()
$1,262
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2811:55 pm -
1 stop26h 25m
Sat 1/3011:00 am -
2 stops33h 45m
Deal found 10/13![United Airlines logo]()
$870
This KLM deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:45 pm -
1 stop15h 25m
Thu 1/145:55 am -
1 stop20h 25m
Deal found 10/13![Multiple Airlines logo]()
$1,188
Last-minute flights from Panama City to SpainDiscover last-minute flight deals from Panama City to Spain. Data last updated October 15, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Spain. Data last updated October 15, 2026 and is based on user searches.
This KLM deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:50 pm -
1 stop14h 35m
Sun 4/116:20 am -
1 stop17h 30m
Deal found 10/11![KLM logo]()
$834
This Air France deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:30 pm -
1 stop18h 35m
Fri 11/206:00 am -
1 stop20h 20m
Deal found 10/13![Air France logo]()
$753
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:41 pm -
2 stops38h 34m
Sun 11/223:10 pm -
2 stops34h 52m
Deal found 10/11![United Airlines logo]()
$764
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:00 am -
2 stops39h 45m
Mon 11/2311:15 am -
2 stops33h 30m
Deal found 10/13![United Airlines logo]()
$768
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:00 am -
1 stop17h 30m
Tue 11/241:25 pm -
2 stops36h 37m
Deal found 10/14![United Airlines logo]()
$771
This Air France deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:30 pm -
1 stop14h 40m
Wed 11/186:00 am -
1 stop20h 20m
Deal found 10/12![Air France logo]()
$778
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:00 am -
1 stop17h 30m
Sat 11/216:25 am -
2 stops19h 37m
Deal found 10/14![United Airlines logo]()
$787
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:00 am -
1 stop17h 30m
Tue 12/81:25 pm -
2 stops31h 20m
Deal found 10/14![United Airlines logo]()
$775
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:00 am -
1 stop17h 30m
Mon 12/711:15 am -
2 stops33h 30m
Deal found 10/14![United Airlines logo]()
$777
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:41 pm -
2 stops33h 04m
Thu 12/1011:15 am -
2 stops33h 30m
Deal found 10/14![United Airlines logo]()
$781
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:00 am -
1 stop16h 20m
Fri 12/410:30 am -
2 stops39h 32m
Deal found 10/13![United Airlines logo]()
$763
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:00 am -
2 stops40h 00m
Fri 12/1111:15 am -
2 stops33h 30m
Deal found 10/13![United Airlines logo]()
$780
One-way flights from Panama City to SpainSearch for one-way flight options from Panama City to Spain. Find affordable one-way fares based on user searches. Data last updated October 15, 2026.
Search for one-way flight options from Panama City to Spain. Find affordable one-way fares based on user searches. Data last updated October 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:30 pm -
Nonstop9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Air Europa logo]()
$512
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:30 pm -
Nonstop9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Air Europa logo]()
$520
This Cheapflightsfares deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:30 pm -
Nonstop9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Air Europa logo]()
$524
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:31 pm -
2 stops44h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$573
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:25 pm -
Nonstop9h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Air Europa logo]()
$578
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:33 pm -
2 stops29h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Multiple Airlines logo]()
$584
This FlightHub deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:33 pm -
2 stops23h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Multiple Airlines logo]()
$589
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:33 pm -
2 stops29h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Multiple Airlines logo]()
$602
This KLM deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:45 pm -
1 stop15h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![KLM logo]()
$617
This KLM deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:45 pm -
1 stop15h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![KLM logo]()
$618
This Air France deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:30 pm -
1 stop14h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Air France logo]()
$619
This KLM deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:45 pm -
1 stop15h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![KLM logo]()
$621
Find flight deals from Panama City to Spain
Keep the following information in mind while searching for Panama City to Spain flight deals. Data was last updated October 15, 2026.
Round-trip from | $750 (Avianca) |
|---|---|
One-way from | $512 (Kiwi.com) |
Popular in | January |
Cheapest in | May |
Average price | $910 |
Good round-trip deal | $827 or less |
Good one-way deal | $653 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 15, 2026.
Use the filters below to find and compare flights from Panama City to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Tue 12/1
9:31 pm-12:25 am
2 stops44h 54m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$573
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Wed 11/4
6:45 pm-4:05 pm
1 stop15h 20m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$617
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Tue 12/1
6:45 pm-4:05 pm
1 stop15h 20m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$617
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Fri 11/27
6:45 pm-4:05 pm
1 stop15h 20m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$617
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Fri 12/4
6:45 pm-4:05 pm
1 stop15h 20m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$618
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Wed 11/18
6:45 pm-4:05 pm
1 stop15h 20m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$618
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Thu 11/19
6:45 pm-11:35 pm
1 stop22h 50m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$618
Quickest round-trip
Panama CityBarcelona
PTY Panama City Tocumen Intl - BCN Barcelona-El Prat
PTYBCN
Panama City Tocumen Intl
Wed 10/28
9:30 pm-4:40 pm
1 stop13h 10m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$624
Panama CityBarcelona
PTY Panama City Tocumen Intl - BCN Barcelona-El Prat
PTYBCN
Panama City Tocumen Intl
Wed 10/28
6:35 pm-5:10 pm
1 stop16h 35m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$650
Panama CityBarcelona
PTY Panama City Tocumen Intl - BCN Barcelona-El Prat
PTYBCN
Panama City Tocumen Intl
Wed 1/13
10:25 am-12:45 am
3 stops32h 20m
Barcelona-El Prat
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$673
Showing 1-10 of 57 resultsSorted by cheapest first
Best time to book a flight from Panama City to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Panama City with our price prediction graph.
PTY-MAD
PTY-BCN
PTY-LPA
PTY-VLC
PTY-AGP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Spain
PTY-ES0
PTY-MAD
PTY-BCN
PTY-LPA
PTY-VLC
What is the cheapest month to book a flight from Panama City to Spain?
Currently, February is the cheapest month in which you can book a flight from Panama City to Spain (average of $771). Flying from Panama City to Spain in July is currently the most expensive (average of $973). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to ES?
Find hourly flight availability from Panama City to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 15, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Spain as you normally would.
Weekly flight availability from Panama City to Spain
Explore weekly flight availability from Panama City to Spain. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 15, 2026.
The most flights from PTY to ES0 are scheduled on a Monday (5 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (4 on average).
How often are flights from Panama City to Spain delayed?
About 13% of weekly flights between Panama City and Spain have experienced delays in the past year, with the average delay time being 153 minutes.
What is the most punctual flight time for Panama City to Spain flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Spain flights?
Over the last year, Air Europa have had the lowest number of delays on this route, with just 10% of flights being delayed.
How far ahead should I book a flight from Panama City to Spain?
Booking 90 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Spain. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Spain
Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated October 15, 2026.
Get a feel of what it's like to fly with Air France,United Airlines, andAir Europa from Panama City to Spain by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.5
Crew
8.2
Food
7.1
Comfort
7.4
Entertainment
7.0
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Overall
7.5
Crew
8.2
Food
7.1
Comfort
7.4
Entertainment
7.0
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Overall
7.5
Crew
8.2
Food
7.1
Comfort
7.4
Entertainment
7.0
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Overall
7.5
Crew
8.2
Food
7.1
Comfort
7.4
Entertainment
7.0
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Overall
7.5
Crew
8.2
Food
7.1
Comfort
7.4
Entertainment
7.0
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Overall
7.5
Crew
8.2
Food
7.1
Comfort
7.4
Entertainment
7.0
Boarding
7.5
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Related info for your journey
Find useful and relevant information for your journey from Panama City to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama City to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Spain by cabin class
Find flights from Panama City to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Spain flights
Browse other Panama City and Spain flight options. Last updated on October 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 8 airlines flying from Panama City to Spain
Discover the top 8 airlines that operate flights from Panama City to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$567 | Average$866 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$618 | Average$1,154 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$644 | Average$900 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$658 | Average$749 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$666 | Average$917 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$696 | Average$981 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$763 | Average$873 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$1,292 | Average$1,396 | FlexibilityNo cancel fee | On-time70% |