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South Carolina

$138+ Cheap flights from Santo Domingo (SDQ) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CHS
ago. 19 — ago. 261
mar. 8/19
mar. 8/26
1 adult, Economy
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Cheap flight deals from Santo Domingo to South Carolina

Keep the following information in mind while searching for Santo Domingo to South Carolina flight deals. Data was last updated agosto 14, 2025.

Round-trip from

$314
(Mytrip)

One-way from

$138
(SmartFares)
From Santo Domingo Las Americas to South Carolina
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One-way flight from Santo Domingo Las Americas to South Carolina
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Find flight deals from Santo Domingo to South Carolina

Cheapest flights from Santo Domingo to South Carolina
Explore the most affordable flight options available from Santo Domingo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 14, 2025.

This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/295:05 pmSDQ - CLT
1 stop16h 17mSpirit Airlines
lun. 10/66:15 amCLT - SDQ
1 stop9h 52mSpirit Airlines
Deal found 8/13$314
This SmartFares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/55:05 pmSDQ - CLT
1 stop16h 17mSpirit Airlines
lun. 9/155:45 amCLT - SDQ
1 stop10h 15mSpirit Airlines
Deal found 8/12$319
This eDestinos deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/95:05 pmSDQ - CLT
1 stop5h 54mSpirit Airlines
mié. 9/2410:46 amCLT - SDQ
1 stop5h 14mSpirit Airlines
Deal found 8/13$329
This CheapOair deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/273:47 pmSDQ - CLT
1 stop7h 12mSpirit Airlines
jue. 10/166:00 amCLT - SDQ
1 stop8h 56mSpirit Airlines
Deal found 8/13$331
This Cheapflightsfares deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/225:05 pmSDQ - CLT
1 stop6h 50mSpirit Airlines
lun. 9/85:45 amCLT - SDQ
1 stop10h 15mSpirit Airlines
Deal found 8/13$336
This FlightHub deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/301:01 pmSDQ - CLT
1 stop8h 58mSpirit Airlines
dom. 9/710:17 amCLT - SDQ
1 stop5h 43mSpirit Airlines
Deal found 8/11$337
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/63:47 pmSDQ - CLT
1 stop17h 35mSpirit Airlines
sáb. 9/205:45 amCLT - SDQ
1 stop8h 57mSpirit Airlines
Deal found 8/14$339
This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/115:05 pmSDQ - CLT
1 stop5h 54mSpirit Airlines
dom. 9/145:45 amCLT - SDQ
1 stop10h 15mSpirit Airlines
Deal found 8/12$342
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/263:45 amSDQ - CHS
1 stop13h 29mDelta
dom. 1/116:00 amCHS - SDQ
1 stop11h 35mDelta
Deal found 8/13$534
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/2910:25 amSDQ - CAE
2 stops13h 34mAmerican Airlines
dom. 9/77:15 amCAE - SDQ
2 stops13h 15mAmerican Airlines
Deal found 8/12$584
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/276:55 pmSDQ - CHS
1 stop16h 50mMultiple Airlines
dom. 1/1111:40 amCHS - SDQ
2 stops27h 49mMultiple Airlines
Deal found 8/13$589
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/272:20 pmSDQ - CHS
2 stops10h 51mAmerican Airlines
dom. 1/117:13 amCHS - SDQ
2 stops7h 22mAmerican Airlines
Deal found 8/13$826

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
Use the filters below to find and compare flights from Santo Domingo to South Carolina that are best for you.

Fly from

Santo Domingo

Fly to

South Carolina

Route

Depart

Return

Price

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

lun. 9/29

5:05 pm-9:22 am

1 stop16h 17m

Charlotte Douglas

lun. 10/6

6:15 am-4:07 pm

1 stop9h 52m

$314

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

vie. 9/5

5:05 pm-9:22 am

1 stop16h 17m

Charlotte Douglas

lun. 9/15

5:45 am-4:00 pm

1 stop10h 15m

$319

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

sáb. 9/6

3:47 pm-10:59 pm

1 stop7h 12m

Charlotte Douglas

sáb. 9/20

5:45 am-2:42 pm

1 stop8h 57m

$319

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

mar. 9/9

5:05 pm-10:59 pm

1 stop5h 54m

Charlotte Douglas

mié. 9/24

10:46 am-4:00 pm

1 stop5h 14m

$329

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

jue. 10/9

4:01 pm-9:59 pm

1 stop5h 58m

Charlotte Douglas

lun. 10/13

3:34 pm-2:56 pm

1 stop23h 22m

$330

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

sáb. 9/27

3:47 pm-10:59 pm

1 stop7h 12m

Charlotte Douglas

jue. 10/16

6:00 am-2:56 pm

1 stop8h 56m

$331

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

sáb. 8/30

1:01 pm-9:59 pm

1 stop8h 58m

Charlotte Douglas

dom. 9/7

10:17 am-4:00 pm

1 stop5h 43m

$337

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

jue. 2/5

4:18 pm-11:19 pm

1 stop8h 01m

Charleston

sáb. 2/7

2:30 pm-11:46 pm

1 stop8h 16m

$488

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

mié. 2/4

2:35 am-11:19 am

1 stop9h 44m

Charleston

sáb. 2/7

12:05 pm-10:23 pm

1 stop9h 18m

$488

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

sáb. 12/27

7:00 am-4:14 pm

1 stop10h 14m

Charleston

dom. 1/11

6:00 am-6:35 pm

1 stop11h 35m

$534

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 28 results
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Best time to book a flight from Santo Domingo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to South Carolina

What is the cheapest time of day to fly from SDQ to SC?

Find hourly flight availability from Santo Domingo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 14, 2025.

When flying from Santo Domingo to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated agosto 14, 2025.
Peruse reviews from past customers who have flown with Delta from Santo Domingo to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to South Carolina?

    Santo Domingo Las Americas (SDQ) is the airport you will fly out of if you book a flight from Santo Domingo to South Carolina. It is only a 17.5 mi journey to Las Americas (SDQ) from Santo Domingo’s city center.

  • What are the most popular routes from Santo Domingo to South Carolina?

    While some choose either Santo Domingo Las Americas - Charleston or Santo Domingo Las Americas - Columbia Metropolitan, Santo Domingo Las Americas - Charlotte Douglas is the most popular route from Santo Domingo to South Carolina.

  • Can I find deals for flights from Santo Domingo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to South Carolina.

  • Can I find deals for business class flights from Santo Domingo to South Carolina?

    Yes. Cheapflights offers flight deals from Santo Domingo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Santo Domingo to South Carolina (average of $217). Flying from Santo Domingo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Santo Domingo to Los Angeles flights

Top airline flying from Santo Domingo to South Carolina

Discover the top airline that operate flights from Santo Domingo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$264Average$466FlexibilityNo cancel feeOn-timeN/A

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