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South Carolina

$149+ Cheap flights from Santo Domingo (SDQ) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CHS
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Santo Domingo to South Carolina

Keep the following information in mind while searching for Santo Domingo to South Carolina flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

$300
(Kiwi.com)

One-way from

$149
(Priceline)
From Santo Domingo Las Americas to South Carolina
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One-way flight from Santo Domingo Las Americas to South Carolina
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Find flight deals from Santo Domingo to South Carolina

Cheapest flights from Santo Domingo to South Carolina
Explore the most affordable flight options available from Santo Domingo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/163:54 pmSDQ - CHS
1 stop17h 12mSpirit Airlines
vie. 11/75:40 pmCHS - SDQ
1 stop23h 10mSpirit Airlines
Deal found 9/10$300
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/225:05 pmSDQ - CLT
1 stop16h 17mSpirit Airlines
vie. 10/310:17 amCLT - SDQ
1 stop5h 43mSpirit Airlines
Deal found 9/11$302
This Cheapflightsfares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/125:05 pmSDQ - CLT
1 stop16h 17mSpirit Airlines
lun. 9/155:45 amCLT - SDQ
1 stop10h 15mSpirit Airlines
Deal found 9/10$303
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/195:05 pmSDQ - CLT
1 stop5h 54mSpirit Airlines
dom. 9/215:45 amCLT - SDQ
1 stop10h 15mSpirit Airlines
Deal found 9/11$305
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/163:54 pmSDQ - CLT
1 stop7h 34mSpirit Airlines
vie. 10/245:45 amCLT - SDQ
1 stop10h 22mSpirit Airlines
Deal found 9/11$321
This Cheapflightsfares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/273:47 pmSDQ - CLT
1 stop7h 12mSpirit Airlines
jue. 10/165:45 amCLT - SDQ
1 stop9h 03mSpirit Airlines
Deal found 9/10$324
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/195:05 pmSDQ - CLT
1 stop16h 17mSpirit Airlines
lun. 9/295:45 amCLT - SDQ
1 stop10h 15mSpirit Airlines
Deal found 9/11$334
This Cheapflightsfares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/263:54 pmSDQ - CLT
1 stop7h 34mSpirit Airlines
dom. 11/25:45 amCLT - SDQ
1 stop9h 03mSpirit Airlines
Deal found 9/10$345
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/166:18 amSDQ - CHS
2 stops26h 48mMultiple Airlines
vie. 11/75:40 pmCHS - SDQ
1 stop23h 10mMultiple Airlines
Deal found 9/10$352
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1010:19 amSDQ - CLT
1 stop12h 38mMultiple Airlines
mar. 12/27:31 pmCLT - SDQ
1 stop19h 55mMultiple Airlines
Deal found 9/11$359
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/195:05 pmSDQ - CLT
1 stop16h 17mSpirit Airlines
mar. 9/3010:46 amCLT - SDQ
1 stop5h 14mSpirit Airlines
Deal found 9/11$362
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/710:25 amSDQ - CHS
2 stops10h 18mAmerican Airlines
dom. 12/76:00 amCHS - SDQ
1 stop5h 28mAmerican Airlines
Deal found 9/11$410

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Santo Domingo to South Carolina that are best for you.

Fly from

Santo Domingo

Fly to

South Carolina

Route

Depart

Return

Price

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

jue. 10/16

3:54 pm-9:06 am

1 stop17h 12m

Charleston

vie. 11/7

5:40 pm-5:50 pm

1 stop23h 10m

$300

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

lun. 9/22

5:05 pm-9:22 am

1 stop16h 17m

Charlotte Douglas

vie. 10/3

10:17 am-4:00 pm

1 stop5h 43m

$302

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

sáb. 9/27

3:47 pm-10:59 pm

1 stop7h 12m

Charlotte Douglas

jue. 10/16

5:45 am-2:48 pm

1 stop9h 03m

$324

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

dom. 10/26

3:54 pm-11:28 pm

1 stop7h 34m

Charlotte Douglas

dom. 11/2

5:45 am-3:48 pm

1 stop9h 03m

$350

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

jue. 10/16

6:18 am-9:06 am

2 stops26h 48m

Charleston

vie. 11/7

5:40 pm-5:50 pm

1 stop23h 10m

$352

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

lun. 11/10

10:19 am-9:57 pm

1 stop12h 38m

Charlotte Douglas

mar. 12/2

7:31 pm-4:26 pm

1 stop19h 55m

$359

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

sáb. 11/8

6:55 pm-12:59 am

1 stop7h 04m

Charlotte Douglas

mar. 12/2

7:31 pm-4:26 pm

1 stop19h 55m

$363

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

mar. 11/18

6:55 pm-12:59 am

1 stop7h 04m

Charlotte Douglas

mar. 2/3

5:45 am-5:50 pm

1 stop11h 05m

$366

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

jue. 11/13

3:35 pm-9:57 pm

1 stop7h 22m

Charlotte Douglas

jue. 11/27

7:31 pm-5:25 am

1 stop8h 54m

$402

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

mar. 10/7

10:25 am-8:43 pm

2 stops10h 18m

Charleston

dom. 12/7

6:00 am-12:28 pm

1 stop5h 28m

$410

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 31 results
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Best time to book a flight from Santo Domingo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to South Carolina

What is the cheapest time of day to fly from SDQ to SC?

Find hourly flight availability from Santo Domingo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

When flying from Santo Domingo to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Santo Domingo to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated septiembre 11, 2025.
Peruse reviews from past customers who have flown with Delta from Santo Domingo to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to South Carolina?

    Santo Domingo Las Americas (SDQ) is the airport you will fly out of if you book a flight from Santo Domingo to South Carolina. It is only a 17.5 mi journey to Las Americas (SDQ) from Santo Domingo’s city center.

  • How long is the flight from Santo Domingo to South Carolina?

    Spirit Airlines, American Airlines, and United Airlines can get you from Santo Domingo to South Carolina in just under 10h 18m. Your travel time can differ by up to 7h 52m. The distance between Santo Domingo and South Carolina is about 1187 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Santo Domingo to South Carolina one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $149. Delta flights start at $216 while deals on American Airlines start at $222 one-way.

  • What are the most popular routes from Santo Domingo to South Carolina?

    While some choose either Santo Domingo Las Americas - Charleston or Santo Domingo Las Americas - Columbia Metropolitan, Santo Domingo Las Americas - Charlotte Douglas is the most popular route from Santo Domingo to South Carolina.

  • Can I find deals for flights from Santo Domingo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to South Carolina.

  • Can I find deals for business class flights from Santo Domingo to South Carolina?

    Yes. Cheapflights offers flight deals from Santo Domingo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Santo Domingo to South Carolina (average of $217). Flying from Santo Domingo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Santo Domingo to South Carolina

Discover the top airline that operate flights from Santo Domingo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$494Average$494FlexibilityNo cancel feeOn-timeN/A

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