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South Carolina

$165+ Cheap flights from Santo Domingo (SDQ) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CHS
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheap flight deals from Santo Domingo to South Carolina

Keep the following information in mind while searching for Santo Domingo to South Carolina flight deals. Data was last updated April 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$300
(Mytrip)

One-way from

$165
(eDestinos)
Provider with most accurate pricing for Santo Domingo Las Americas-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Myrtle Beach Intl flights.
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From Santo Domingo Las Americas to South Carolina
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One-way flight from Santo Domingo Las Americas to South Carolina
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Find flight deals from Santo Domingo to South Carolina

Cheapest flights from Santo Domingo to South Carolina
Explore the most affordable flight options available from Santo Domingo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/291:05 pmSDQ - CLT
1 stop20h 05mFrontier
Tue 8/124:07 pmCLT - SDQ
1 stop25h 18mFrontier
Deal found 4/29$300
This Booking.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1712:58 pmSDQ - CLT
1 stop20h 06mMultiple Airlines
Tue 8/1911:52 amCLT - SDQ
1 stop13h 49mMultiple Airlines
Deal found 4/29$347
This eDestinos deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/214:05 pmSDQ - CLT
1 stop5h 55mSpirit Airlines
Mon 5/268:50 amCLT - SDQ
1 stop6h 55mSpirit Airlines
Deal found 4/29$353
This Cheapflightsfares deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/73:50 pmSDQ - CHS
1 stop16h 48mSpirit Airlines
Sat 6/219:42 amCHS - SDQ
1 stop4h 57mSpirit Airlines
Deal found 4/29$374
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/94:50 pmSDQ - CHS
1 stop15h 48mMultiple Airlines
Tue 5/206:00 amCHS - SDQ
2 stops17h 11mMultiple Airlines
Deal found 4/29$407
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/710:13 amSDQ - CHS
2 stops9h 32mAmerican Airlines
Sat 6/217:34 pmCHS - SDQ
1 stop13h 39mAmerican Airlines
Deal found 4/29$502
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/96:10 amSDQ - CLT
2 stops14h 52mDelta
Wed 9/245:30 amCLT - SDQ
2 stops12h 21mDelta
Deal found 4/29$513
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/107:00 amSDQ - CLT
1 stop7h 00mAmerican Airlines
Fri 7/255:17 amCLT - SDQ
1 stop15h 38mAmerican Airlines
Deal found 4/28$521
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/65:00 amSDQ - CAE
2 stops12h 38mAmerican Airlines
Thu 5/1510:45 amCAE - SDQ
2 stops11h 55mAmerican Airlines
Deal found 4/29$537
This JetBlue deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/99:04 pmSDQ - CHS
1 stop12h 50mJetBlue
Wed 5/2110:57 amCHS - SDQ
1 stop13h 55mJetBlue
Deal found 4/29$591
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/67:00 amSDQ - CHS
2 stops14h 31mDelta
Tue 5/207:00 amCHS - SDQ
1 stop11h 28mDelta
Deal found 4/29$596
This Copa Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/12:07 pmSDQ - CLT
2 stops19h 41mCopa Airlines
Thu 7/106:00 amCLT - SDQ
2 stops20h 45mCopa Airlines
Deal found 4/29$608

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Santo Domingo to South Carolina that are best for you.

Fly from

Santo Domingo

Fly to

South Carolina

Route

Depart

Return

Price

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Tue 7/29

1:05 pm-9:10 am

1 stop20h 05m

Charlotte Douglas

Tue 8/12

4:07 pm-5:25 pm

1 stop25h 18m

$300

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Tue 6/17

12:58 pm-9:04 am

1 stop20h 06m

Charlotte Douglas

Tue 8/19

11:52 am-1:41 am

1 stop13h 49m

$347

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Wed 5/21

4:05 pm-10:00 pm

1 stop5h 55m

Charlotte Douglas

Mon 5/26

8:50 am-3:45 pm

1 stop6h 55m

$353

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Sat 6/7

3:50 pm-8:38 am

1 stop16h 48m

Charleston

Sat 6/21

9:42 am-2:39 pm

1 stop4h 57m

$374

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 5/9

4:50 pm-8:38 am

1 stop15h 48m

Charleston

Tue 5/20

6:00 am-11:11 pm

2 stops17h 11m

$407

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Sat 6/7

7:10 pm-10:23 am

2 stops15h 13m

Charleston

Sat 6/21

8:30 pm-9:13 am

2 stops12h 43m

$502

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Tue 9/9

6:10 am-9:02 pm

2 stops14h 52m

Charlotte Douglas

Wed 9/24

5:30 am-5:51 pm

2 stops12h 21m

$513

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Tue 6/10

7:00 am-2:00 pm

1 stop7h 00m

Charlotte Douglas

Fri 7/25

5:17 am-8:55 pm

1 stop15h 38m

$521

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 5/9

9:04 pm-9:54 am

1 stop12h 50m

Charleston

Wed 5/21

10:57 am-12:52 am

1 stop13h 55m

$591

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 5/9

2:41 pm-10:35 pm

1 stop7h 54m

Charleston

Tue 5/20

12:18 pm-12:19 am

1 stop12h 01m

$596

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 27 results
1
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Best time to book a flight from Santo Domingo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to South Carolina

What is the cheapest time of day to fly from SDQ to SC?

Find hourly flight availability from Santo Domingo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

When flying from Santo Domingo to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 29, 2025.
See what other customers who have flown with Delta, Copa Airlines and United Airlines from Santo Domingo to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,936 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.5
Good
1,411 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
JetBlue
7.3
Good
2,922 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to South Carolina?

    Santo Domingo Las Americas (SDQ) is the airport you will fly out of if you book a flight from Santo Domingo to South Carolina. It is only a 17.5 mi journey to Las Americas (SDQ) from Santo Domingo’s city center.

  • What are the cheapest airlines to fly from Santo Domingo to South Carolina one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $165. Frontier flights start at $166 while deals on Delta start at $310 one-way.

  • What are the most popular routes from Santo Domingo to South Carolina?

    While some choose either Santo Domingo Las Americas - Charleston or Santo Domingo Las Americas - Columbia Metropolitan, Santo Domingo Las Americas - Charlotte Douglas is the most popular route from Santo Domingo to South Carolina.

  • Can I find deals for flights from Santo Domingo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to South Carolina.

  • Can I find deals for business class flights from Santo Domingo to South Carolina?

    Yes. Cheapflights offers flight deals from Santo Domingo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Santo Domingo to South Carolina (average of $217). Flying from Santo Domingo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Santo Domingo to John F Kennedy Intl flights
Santo Domingo to Newark flights
Santiago de los Caballeros to John F Kennedy Intl flights
Santiago de los Caballeros to Newark flights
Santo Domingo to Boston flights
Santo Domingo to LaGuardia flights
Santo Domingo to Orlando flights
Santo Domingo to Miami flights
Santo Domingo to Fort Lauderdale flights
Punta Cana to John F Kennedy Intl flights
Punta Cana to Newark flights
Santo Domingo to Atlanta flights
Santiago de los Caballeros to Orlando flights
Santiago de los Caballeros to LaGuardia flights
Santo Domingo to Dallas/Fort Worth flights
Santiago de los Caballeros to Boston flights
Santiago de los Caballeros to Miami flights
Puerto Plata to John F Kennedy Intl flights
Punta Cana to LaGuardia flights
Santo Domingo to O'Hare Intl flights
Punta Cana to Orlando flights
Punta Cana to Boston flights
Punta Cana to Atlanta flights
Santo Domingo to Los Angeles flights
Santo Domingo to Charlotte flights
Santo Domingo to Philadelphia flights
Punta Cana to O'Hare Intl flights
Punta Cana to Fort Lauderdale flights
Santo Domingo to Tampa flights
Santo Domingo to Love Field flights
Santo Domingo to Las Vegas flights
Santo Domingo to Hobby flights
Santiago de los Caballeros to Fort Lauderdale flights
Santo Domingo to Dulles Intl flights
Santo Domingo to Raleigh flights
Punta Cana to Philadelphia flights
Punta Cana to Dallas/Fort Worth flights
Santiago de los Caballeros to Dallas/Fort Worth flights
Santo Domingo to Reagan-National flights
Santo Domingo to Baltimore flights
Punta Cana to Hobby flights
Santo Domingo to George Bush Intcntl flights
Punta Cana to Miami flights
Punta Cana to George Bush Intcntl flights
Punta Cana to Dulles Intl flights
Santo Domingo to Midway flights
Santiago de los Caballeros to Philadelphia flights
Santo Domingo to West Palm Beach flights
Punta Cana to Las Vegas flights
Santo Domingo to Cleveland flights

Top 2 airlines flying from Santo Domingo to South Carolina

Discover the top 2 airlines that operate flights from Santo Domingo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$449Average$494FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$525Average$575FlexibilityNo cancel feeOn-time71%

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