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South Carolina

$102+ Cheap flights from Portland (PDX) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Portland to South Carolina

Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This CheapOair deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:48 pm
PDX
-
CLT
1 stop26h 06m
Frontier
Mon 4/207:49 pm
CLT
-
PDX
1 stop20h 13m
Frontier
Deal found 1/26$212
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:18 pm
PDX
-
CLT
2 stops36h 33m
Frontier
Sun 3/87:43 pm
CLT
-
PDX
1 stop18h 26m
Frontier
Deal found 1/25$218
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/612:04 pm
PDX
-
CLT
1 stop27h 24m
Frontier
Sun 3/87:43 pm
CLT
-
PDX
1 stop18h 26m
Frontier
Deal found 1/25$230
This CheapOair deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:48 pm
PDX
-
CLT
1 stop26h 06m
Frontier
Tue 5/57:49 pm
CLT
-
PDX
1 stop20h 13m
Frontier
Deal found 1/26$252
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2412:09 pm
PDX
-
CHS
1 stop8h 45m
Delta
Tue 3/104:51 pm
CHS
-
PDX
1 stop8h 17m
Delta
Deal found 1/26$257
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:18 pm
PDX
-
CLT
2 stops36h 33m
Frontier
Thu 3/127:43 pm
CLT
-
PDX
1 stop18h 26m
Frontier
Deal found 1/25$259
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/79:24 am
PDX
-
CLT
2 stops29h 24m
Frontier
Thu 3/127:43 pm
CLT
-
PDX
1 stop18h 26m
Frontier
Deal found 1/25$261
This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:48 am
PDX
-
CLT
1 stop28h 06m
Frontier
Thu 4/237:49 pm
CLT
-
PDX
1 stop18h 14m
Frontier
Deal found 1/27$267
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/612:04 pm
PDX
-
CLT
1 stop27h 24m
Frontier
Thu 3/127:43 pm
CLT
-
PDX
1 stop18h 26m
Frontier
Deal found 1/25$270
This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:48 am
PDX
-
CLT
1 stop28h 06m
Frontier
Mon 4/277:49 pm
CLT
-
PDX
1 stop20h 13m
Frontier
Deal found 1/27$273
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/612:04 pm
PDX
-
CLT
1 stop27h 24m
Frontier
Wed 3/111:59 pm
CLT
-
PDX
2 stops24h 10m
Frontier
Deal found 1/25$276
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/612:04 pm
PDX
-
CLT
2 stops22h 46m
Frontier
Sat 3/77:23 pm
CLT
-
PDX
1 stop17h 46m
Frontier
Deal found 1/25$281

Find flight deals from Portland to South Carolina

Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$212
(CheapOair)

One-way from

$102
(CheapOair)

Popular in

March

Cheapest in

September

Average price

$441
Provider with most accurate pricing for Portland-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Myrtle Beach Intl flights.
Search Deals
From Portland to South Carolina
Search Deals
One-way flight from Portland to South Carolina
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($45 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Portland

Fly to

South Carolina

Route

Depart

Return

Price

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Sat 2/28

9:45 pm-9:22 am

1 stop8h 37m

Charleston

Tue 3/10

5:27 am-10:30 am

1 stop8h 03m

$257

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Mon 2/23

9:45 pm-9:23 am

1 stop8h 38m

Charleston

Tue 3/10

4:51 pm-10:08 pm

1 stop8h 17m

$296

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Sun 3/1

11:59 pm-12:30 pm

1 stop9h 31m

Charleston

Sat 3/7

2:48 pm-8:40 pm

1 stop8h 52m

$331

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Mon 4/13

11:59 pm-11:44 am

1 stop8h 45m

Charleston

Tue 4/21

7:15 am-12:22 pm

1 stop8h 07m

$335

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Thu 6/11

9:45 pm-9:42 am

1 stop8h 57m

Charleston

Mon 6/15

5:55 pm-11:59 pm

1 stop9h 04m

$335

PortlandAugusta

PDX - AGS

PDXAGS

Portland

Mon 3/30

10:30 pm-9:16 am

1 stop7h 46m

Augusta Bush Field

Wed 4/8

3:00 pm-8:25 pm

1 stop8h 25m

$337

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Fri 5/8

5:45 pm-9:42 am

2 stops12h 57m

Charleston

Tue 5/12

2:25 pm-10:22 pm

2 stops10h 57m

$338

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Fri 5/1

11:59 pm-12:45 pm

2 stops9h 46m

Charleston

Fri 5/8

4:20 pm-11:42 pm

1 stop10h 22m

$340

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Thu 5/28

6:44 pm-10:01 am

2 stops12h 17m

Charleston

Tue 6/2

6:00 am-11:38 am

1 stop8h 38m

$340

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Fri 5/1

11:06 pm-11:20 am

1 stop9h 14m

Charleston

Fri 5/8

3:10 pm-11:41 pm

2 stops11h 31m

$340

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 60 results
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Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

What is the cheapest month to book a flight from Portland to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Portland to South Carolina (average of $183). Flying from Portland to South Carolina in March is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to SC?

Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 27, 2026.

One of the essential ways to save on airfare from Portland to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 43% on airfare.

What is the cheapest day to fly from Portland to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Portland to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their Portland to South Carolina flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 27, 2026.
See what other customers who have flown with Alaska Airlines, Southwest, and Delta from Portland to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,799 reviews

Crew

8.5

Food

7.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
Alaska Airlines
8.0
Very good
11,799 reviews
Alaska Airlines
8.0
Very good
11,799 reviews

Crew

8.5

Food

7.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
Southwest
8.0
Very good
4,268 reviews
Alaska Airlines
8.0
Very good
11,799 reviews

Crew

8.5

Food

7.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
Delta
7.9
Good
8,120 reviews
Alaska Airlines
8.0
Very good
11,799 reviews

Crew

8.5

Food

7.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
United Airlines
7.4
Good
9,206 reviews
Alaska Airlines
8.0
Very good
11,799 reviews

Crew

8.5

Food

7.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
American Airlines
7.2
Good
11,198 reviews
Alaska Airlines
8.0
Very good
11,799 reviews

Crew

8.5

Food

7.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading

Related info for your journey

Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to South Carolina?

    Portland (PDX), located 6.0 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.

  • How long is the flight from Portland to South Carolina?

    There are many flights that can get you from Portland to South Carolina in 8h 37m. Fly via Delta, American Airlines, or Southwest to get the fastest option. The distance between Portland and South Carolina is about 2405 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Portland to South Carolina one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $127. However, be on the lookout for offers from Delta and Alaska Airlines, as they are both options that can get you from Portland to South Carolina for a low price.

  • What are the most popular routes from Portland to South Carolina?

    While some choose either Portland - Charleston or Portland - Savannah/Hilton Head, Portland - Charlotte Douglas is the most popular route from Portland to South Carolina.

  • Can I find deals for flights from Portland to South Carolina that include hotel bookings?

    Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.

  • Can I find deals for business class flights from Portland to South Carolina?

    Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Portland to South Carolina (average of $183). Flying from Portland to South Carolina in March is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Portland to South Carolina

Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$162Average$449FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$254Average$459FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$284Average$526FlexibilityNo cancel feeOn-time71%
Alaska AirlinesCheapest$298Average$488FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$354Average$536FlexibilityNo cancel feeOn-time63%

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