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South Carolina

$76+ Cheap flights from Portland (PDX) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Portland to South Carolina

Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:15 pmPDX - CHS
1 stop8h 35mAmerican Airlines
Wed 12/107:00 amCHS - PDX
1 stop8h 59mAmerican Airlines
Deal found 10/27$275
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/812:32 amPDX - CHS
2 stops11h 43mDelta
Sat 12/135:00 pmCHS - PDX
1 stop8h 19mDelta
Deal found 10/28$280
This Alaska Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:49 pmPDX - CHS
1 stop21h 35mAlaska Airlines
Tue 12/167:24 pmCHS - PDX
1 stop17h 08mAlaska Airlines
Deal found 10/28$284
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/211:20 pmPDX - CHS
1 stop8h 26mDelta
Wed 12/1012:51 pmCHS - PDX
2 stops12h 19mDelta
Deal found 10/28$302
This Alaska Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/51:34 pmPDX - CHS
1 stop25h 50mAlaska Airlines
Mon 12/87:24 pmCHS - PDX
1 stop17h 08mAlaska Airlines
Deal found 10/29$304
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:30 pmPDX - CHS
2 stops12h 16mDelta
Tue 12/163:15 pmCHS - PDX
2 stops10h 25mDelta
Deal found 10/28$306
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:30 pmPDX - CHS
2 stops12h 16mDelta
Mon 12/1512:51 pmCHS - PDX
2 stops12h 49mDelta
Deal found 10/29$326
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:51 pmPDX - GSP
2 stops27h 32mMultiple Airlines
Fri 12/1210:01 amGSP - PDX
1 stop25h 52mMultiple Airlines
Deal found 10/27$330
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:47 pmPDX - CLT
1 stop19h 35mFrontier
Fri 1/212:17 pmCLT - PDX
1 stop26h 35mFrontier
Deal found 10/28$335
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2112:47 pmPDX - CLT
1 stop19h 35mFrontier
Thu 1/19:27 amCLT - PDX
2 stops37h 23mFrontier
Deal found 10/28$340
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:47 pmPDX - CLT
1 stop19h 35mFrontier
Tue 12/302:22 pmCLT - PDX
2 stops27h 38mFrontier
Deal found 10/28$342
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/103:26 pmPDX - CLT
2 stops22h 22mFrontier
Thu 11/136:07 pmCLT - PDX
1 stop20h 49mFrontier
Deal found 10/26$350

Cheap flight deals from Portland to South Carolina

Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$275
(American Airlines)

One-way from

$76
(CheapOair)

Popular in

December

Cheapest in

February

Average price

$529
Provider with most accurate pricing for Portland-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Myrtle Beach Intl flights.
Search Deals
From Portland to South Carolina
Search Deals
One-way flight from Portland to South Carolina
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($15 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Portland

Fly to

South Carolina

Route

Depart

Return

Price

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Tue 12/2

10:15 pm-9:50 am

1 stop8h 35m

Charleston

Wed 12/10

7:00 am-12:59 pm

1 stop8h 59m

$275

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Mon 12/8

12:32 am-1:43 pm

2 stops10h 11m

Charleston

Sat 12/13

6:00 am-12:40 pm

2 stops9h 40m

$285

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Sat 2/14

9:45 pm-9:52 am

1 stop9h 07m

Greenville

Tue 2/17

3:00 pm-10:22 pm

2 stops10h 22m

$300

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Tue 12/2

11:20 pm-10:46 am

1 stop8h 26m

Charleston

Wed 12/10

12:51 pm-10:10 pm

2 stops12h 19m

$302

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Wed 2/25

6:00 am-5:31 pm

1 stop8h 31m

Charleston

Sun 3/1

6:45 pm-12:03 am

1 stop8h 18m

$304

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Fri 12/12

5:49 pm-6:24 pm

1 stop21h 35m

Charleston

Mon 12/15

7:24 pm-1:50 pm

1 stop21h 26m

$304

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Sun 1/11

9:45 pm-9:19 am

1 stop8h 34m

Charleston

Sat 1/17

12:00 pm-8:27 pm

1 stop11h 27m

$305

PortlandColumbia

PDX - CAE

PDXCAE

Portland

Fri 2/6

10:15 pm-9:42 am

1 stop8h 27m

Columbia Metropolitan

Mon 2/9

4:57 pm-10:11 pm

1 stop8h 14m

$309

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Fri 12/12

11:20 pm-10:46 am

1 stop8h 26m

Charleston

Tue 12/16

8:00 am-4:00 pm

2 stops11h 00m

$310

PortlandColumbia

PDX - CAE

PDXCAE

Portland

Fri 2/6

7:51 pm-10:17 am

2 stops11h 26m

Columbia Metropolitan

Mon 2/9

5:07 pm-10:32 pm

1 stop8h 25m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results
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Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

What is the cheapest month to book a flight from Portland to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Portland to South Carolina (average of $183). Flying from Portland to South Carolina in December is currently the most expensive (average of $317). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to SC?

Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

One of the essential ways to save on airfare from Portland to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 26% on airfare.

What is the cheapest day to fly from Portland to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Portland to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Portland to South Carolina flight should consider departing on Monday afternoons when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 29, 2025.
See what other customers who have flown with Alaska Airlines, Southwest, and Delta from Portland to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,210 reviews

Comfort

7.8

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.
Alaska Airlines
8.0
Very good
11,210 reviews
Alaska Airlines
8.0
Very good
11,210 reviews

Comfort

7.8

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.
Southwest
8.0
Very good
4,241 reviews
Alaska Airlines
8.0
Very good
11,210 reviews

Comfort

7.8

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.
Delta
7.9
Good
7,992 reviews
Alaska Airlines
8.0
Very good
11,210 reviews

Comfort

7.8

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.
United Airlines
7.4
Good
8,999 reviews
Alaska Airlines
8.0
Very good
11,210 reviews

Comfort

7.8

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.
American Airlines
7.2
Good
11,032 reviews
Alaska Airlines
8.0
Very good
11,210 reviews

Comfort

7.8

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.

Related info for your journey

Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to South Carolina?

    Portland (PDX), located 6.0 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.

  • How long is the flight from Portland to South Carolina?

    There are many flights that can get you from Portland to South Carolina in 8h 31m. Fly via American Airlines, Delta, or Alaska Airlines to get the fastest option. The distance between Portland and South Carolina is about 2405 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Portland to South Carolina one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $106. However, be on the lookout for offers from American Airlines and Southwest, as they are both options that can get you from Portland to South Carolina for a low price.

  • What are the most popular routes from Portland to South Carolina?

    While some choose either Portland - Charleston or Portland - Savannah/Hilton Head, Portland - Charlotte Douglas is the most popular route from Portland to South Carolina.

  • Can I find deals for flights from Portland to South Carolina that include hotel bookings?

    Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.

  • Can I find deals for business class flights from Portland to South Carolina?

    Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Portland to South Carolina (average of $183). Flying from Portland to South Carolina in December is currently the most expensive (average of $317). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Portland to South Carolina

Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$465FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$273Average$566FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$274Average$455FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$284Average$537FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$366Average$540FlexibilityNo cancel feeOn-time63%

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