HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$99+ Cheap flights from Portland (PDX) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Portland to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Portland to South Carolina

Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated June 12, 2025.

Round-trip from

$247
(Mytrip)

One-way from

$99
(Delta)

Popular in

October

Cheapest in

February

Average price

$461
From Portland to South Carolina
Search Deals
One-way flight from Portland to South Carolina
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Portland to South Carolina

Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/298:46 amPDX - MYR
1 stop24h 01mMultiple Airlines
Fri 9/55:54 pmMYR - PDX
2 stops22h 36mMultiple Airlines
Deal found 6/11$247
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1911:01 pmPDX - CHS
1 stop9h 30mAmerican Airlines
Tue 8/262:40 pmCHS - PDX
1 stop9h 35mAmerican Airlines
Deal found 6/12$255
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/189:30 pmPDX - AGS
1 stop8h 48mDelta
Tue 7/225:50 pmAGS - PDX
1 stop6h 59mDelta
Deal found 6/11$277
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/106:20 amPDX - CAE
2 stops14h 21mDelta
Sat 9/205:10 pmCAE - PDX
1 stop8h 22mDelta
Deal found 6/11$282
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:00 amPDX - GSP
2 stops11h 16mDelta
Sat 10/116:45 amGSP - PDX
1 stop7h 11mDelta
Deal found 6/11$282
This Booking.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/123:10 pmPDX - CLT
2 stops15h 52mSpirit Airlines
Wed 7/169:28 pmCLT - PDX
1 stop14h 50mSpirit Airlines
Deal found 6/9$282
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/189:22 amPDX - CHS
1 stop19h 44mMultiple Airlines
Mon 7/219:38 amCHS - PDX
3 stops31h 37mMultiple Airlines
Deal found 6/11$286
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/183:10 pmPDX - CLT
1 stop19h 30mMultiple Airlines
Sun 7/272:56 pmCLT - PDX
1 stop27h 51mMultiple Airlines
Deal found 6/10$288
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:00 amPDX - SAV
1 stop11h 26mDelta
Mon 12/83:50 pmSAV - PDX
1 stop9h 42mDelta
Deal found 6/12$297
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:15 amPDX - MYR
1 stop8h 10mSouthwest
Thu 11/202:55 pmMYR - PDX
1 stop7h 25mSouthwest
Deal found 6/11$297
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/45:30 amPDX - GSP
1 stop8h 33mAmerican Airlines
Tue 8/125:43 pmGSP - PDX
1 stop8h 16mAmerican Airlines
Deal found 6/11$298
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/259:22 amPDX - SAV
1 stop10h 23mMultiple Airlines
Mon 7/2812:00 pmSAV - PDX
3 stops29h 15mMultiple Airlines
Deal found 6/11$299

Cheapflights Fare Finder

Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Portland

Fly to

South Carolina

Route

Depart

Return

Price

PortlandMyrtle Beach

PDX - MYR

PDXMYR

Portland

Fri 8/29

8:46 am-11:47 am

1 stop24h 01m

Myrtle Beach Intl

Fri 9/5

5:54 pm-1:30 pm

2 stops22h 36m

$247

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Tue 8/19

11:01 pm-11:31 am

1 stop9h 30m

Charleston

Tue 8/26

7:06 am-12:54 pm

1 stop8h 48m

$255

PortlandAugusta

PDX - AGS

PDXAGS

Portland

Fri 7/18

9:30 pm-9:18 am

1 stop8h 48m

Augusta Bush Field

Tue 7/22

5:50 pm-9:49 pm

1 stop6h 59m

$277

PortlandCharlotte

PDX - CLT

PDXCLT

Portland

Sat 7/12

3:10 pm-10:02 am

2 stops15h 52m

Charlotte Douglas

Wed 7/16

9:28 pm-9:18 am

1 stop14h 50m

$282

PortlandColumbia

PDX - CAE

PDXCAE

Portland

Wed 9/10

6:20 am-11:41 pm

2 stops14h 21m

Columbia Metropolitan

Sat 9/20

5:10 pm-10:32 pm

1 stop8h 22m

$282

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Wed 10/1

6:00 am-8:16 pm

2 stops11h 16m

Greenville

Sat 10/11

6:45 am-10:56 am

1 stop7h 11m

$282

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Fri 7/18

9:22 am-8:06 am

1 stop19h 44m

Charleston

Mon 7/21

9:38 am-2:15 pm

3 stops31h 37m

$286

PortlandCharlotte

PDX - CLT

PDXCLT

Portland

Fri 7/18

3:10 pm-1:40 pm

1 stop19h 30m

Charlotte Douglas

Sun 7/27

2:56 pm-3:47 pm

1 stop27h 51m

$288

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Mon 8/4

5:30 am-5:03 pm

1 stop8h 33m

Greenville

Tue 8/12

5:43 pm-10:59 pm

1 stop8h 16m

$298

PortlandSavannah

PDX - SAV

PDXSAV

Portland

Fri 7/25

9:22 am-10:45 pm

1 stop10h 23m

Savannah/Hilton Head

Mon 7/28

12:00 pm-2:15 pm

3 stops29h 15m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

What is the cheapest month to book a flight from Portland to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Portland to South Carolina (average of $217). Flying from Portland to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to SC?

Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Portland to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 12, 2025.
Read reviews from past customers who have flown Alaska Airlines, Southwest and Delta from Portland to South Carolina. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,946 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
JetBlue
7.3
Good
2,925 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to South Carolina?

    Portland (PDX), located 6.0 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.

  • What are the cheapest airlines to fly from Portland to South Carolina one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $99. However, be on the lookout for offers from Allegiant Air and Spirit Airlines, as they are both options that can get you from Portland to South Carolina for a low price.

  • What are the most popular routes from Portland to South Carolina?

    While some choose either Portland - Charleston or Portland - Greenville, Portland - Charlotte Douglas is the most popular route from Portland to South Carolina.

  • Can I find deals for flights from Portland to South Carolina that include hotel bookings?

    Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.

  • Can I find deals for business class flights from Portland to South Carolina?

    Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Portland to South Carolina (average of $217). Flying from Portland to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Portland to Los Angeles flights
Portland to John F Kennedy Intl flights
Portland to Las Vegas flights
Portland to O'Hare Intl flights
Portland to Newark flights
Portland to Denver flights
Portland to Dallas/Fort Worth flights
Portland to Honolulu flights
Portland to Santa Ana flights
Portland to San Diego flights
Portland to Sky Harbor Intl flights
Portland to Orlando flights
Portland to San Francisco flights
Portland to LaGuardia flights
Portland to Boston flights
Portland to Ontario flights
Portland to Kahului flights
Portland to Burbank flights
Boise to Seattle flights
Portland to San Jose flights
Portland to Minneapolis flights
Portland to Reagan-National flights
Portland to Detroit flights
Portland to Atlanta flights
Portland to Nashville flights
Portland to Hobby flights
Portland to Dulles Intl flights
Portland to Kailua-Kona flights
Portland to Salt Lake City flights
Portland to George Bush Intcntl flights
Boise to Las Vegas flights
Portland to Sacramento flights
Portland to Albuquerque flights
Portland to Austin flights
Portland to Reno flights
Portland to Midway flights
Portland to Baltimore flights
Boise to Los Angeles flights
Boise to Denver flights
Boise to O'Hare Intl flights
Portland to Omaha flights
Portland to New Orleans flights
Portland to Anchorage flights
Portland to Miami flights
Portland to Kansas City flights
Portland to Lihue flights
Portland to Palm Springs flights
Eugene to Los Angeles flights
Boise to San Diego flights
Portland to Philadelphia flights

Top 6 airlines flying from Portland to South Carolina

Discover the top 6 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$166Average$257FlexibilityNo cancel feeOn-time65%
DeltaCheapest$254Average$497FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$273Average$575FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$276Average$515FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$289Average$520FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$366Average$557FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.