South Carolina

$92+ Cheap flights from Portland (PDX) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
oct. 11 — oct. 181
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Cheap flight deals from Portland to South Carolina

Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

$221
(American Airlines)

One-way from

$92
(Southwest)

Popular in

December

Cheapest in

February

Average price

$426
From Portland to South Carolina
One-way flight from Portland to South Carolina
Highest demand for flights based on searches. 1% potential increase in price ($10 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from Portland to South Carolina

Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/287:12 amPDX - CHS
1 stop10h 48mDelta
mié. 11/56:00 amCHS - PDX
1 stop9h 06mDelta
Deal found 9/9$197
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/17:12 amPDX - CHS
1 stop10h 48mDelta
mié. 11/56:00 amCHS - PDX
1 stop9h 06mDelta
Deal found 9/9$209
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/811:59 pmPDX - CHS
1 stop8h 57mAmerican Airlines
sáb. 11/157:00 amCHS - PDX
1 stop9h 06mAmerican Airlines
Deal found 9/11$221
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/287:12 amPDX - CHS
1 stop10h 48mDelta
lun. 11/36:00 amCHS - PDX
1 stop9h 06mDelta
Deal found 9/9$223
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/712:40 amPDX - CHS
2 stops12h 31mDelta
sáb. 11/158:05 amCHS - PDX
1 stop7h 47mDelta
Deal found 9/11$226
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/310:15 pmPDX - CHS
1 stop8h 31mAmerican Airlines
sáb. 11/84:15 pmCHS - PDX
1 stop8h 00mAmerican Airlines
Deal found 9/10$235
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/312:10 pmPDX - CHS
1 stop6h 49mDelta
mié. 11/512:50 pmCHS - PDX
1 stop11h 14mDelta
Deal found 9/9$236
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1210:15 pmPDX - CHS
1 stop7h 23mAmerican Airlines
mar. 12/163:21 pmCHS - PDX
1 stop11h 02mAmerican Airlines
Deal found 9/10$237
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/35:07 pmPDX - CHS
2 stops14h 13mDelta
sáb. 11/86:00 amCHS - PDX
1 stop9h 06mDelta
Deal found 9/9$240
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/3111:58 pmPDX - CHS
2 stops10h 25mAmerican Airlines
mié. 11/53:21 pmCHS - PDX
1 stop11h 05mAmerican Airlines
Deal found 9/10$241
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/2911:58 pmPDX - SAV
1 stop8h 31mAmerican Airlines
mar. 11/43:52 pmSAV - PDX
1 stop8h 31mAmerican Airlines
Deal found 9/10$249
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/2812:40 amPDX - SAV
2 stops10h 48mDelta
mar. 11/45:47 pmSAV - PDX
1 stop7h 21mDelta
Deal found 9/10$254

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Portland

Fly to

South Carolina

Route

Depart

Return

Price

PortlandCharleston

PDX - CHS

PDXCHS

Portland

mar. 10/28

7:12 am-9:00 pm

1 stop10h 48m

Charleston

mar. 11/4

2:30 pm-7:06 pm

1 stop7h 36m

$197

PortlandCharleston

PDX - CHS

PDXCHS

Portland

vie. 11/7

12:40 am-4:11 pm

2 stops12h 31m

Charleston

sáb. 11/15

8:05 am-12:52 pm

1 stop7h 47m

$226

PortlandCharleston

PDX - CHS

PDXCHS

Portland

lun. 11/3

10:15 pm-9:46 am

1 stop8h 31m

Charleston

sáb. 11/8

4:15 pm-9:15 pm

1 stop8h 00m

$235

PortlandCharleston

PDX - CHS

PDXCHS

Portland

lun. 11/3

5:07 pm-10:20 am

2 stops14h 13m

Charleston

sáb. 11/8

6:00 am-12:06 pm

1 stop9h 06m

$240

PortlandCharleston

PDX - CHS

PDXCHS

Portland

vie. 10/31

5:07 pm-10:21 am

2 stops14h 14m

Charleston

mié. 11/5

5:35 am-2:38 pm

2 stops12h 03m

$246

PortlandCharleston

PDX - CHS

PDXCHS

Portland

sáb. 11/1

2:10 pm-11:59 pm

1 stop6h 49m

Charleston

mar. 11/4

12:50 pm-9:04 pm

1 stop11h 14m

$250

PortlandGreenville

PDX - GSP

PDXGSP

Portland

mié. 10/1

5:01 pm-9:13 am

2 stops13h 12m

Greenville

sáb. 10/11

5:16 pm-10:08 pm

1 stop7h 52m

$254

PortlandSavannah

PDX - SAV

PDXSAV

Portland

mar. 10/28

12:40 am-2:28 pm

2 stops10h 48m

Savannah/Hilton Head

mar. 11/4

5:40 am-12:50 pm

2 stops10h 10m

$259

PortlandGreenville

PDX - GSP

PDXGSP

Portland

mié. 10/8

5:07 pm-8:59 am

2 stops12h 52m

Greenville

mié. 10/15

9:54 am-7:00 pm

2 stops12h 06m

$259

PortlandCharleston

PDX - CHS

PDXCHS

Portland

dom. 11/2

7:12 am-9:00 pm

1 stop10h 48m

Charleston

sáb. 11/8

6:00 am-12:06 pm

1 stop9h 06m

$263

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 60 results
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Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

What is the cheapest month to book a flight from Portland to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Portland to South Carolina (average of $217). Flying from Portland to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to SC?

Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

When flying from Portland to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated septiembre 11, 2025.
See what other customers who have flown with Alaska Airlines, Southwest, and Delta from Portland to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

8.0

Comfort

7.8

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Overall

8.0

Comfort

7.8

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Overall

8.0

Comfort

7.8

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
8.0
Very good

Overall

8.0

Comfort

7.8

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Overall

8.0

Comfort

7.8

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Overall

8.0

Comfort

7.8

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Portland to South Carolina?

    Portland (PDX), located 6.0 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.

  • How long is the flight from Portland to South Carolina?

    There are many flights that can get you from Portland to South Carolina in 8h 31m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. The distance between Portland and South Carolina is about 2405 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Portland to South Carolina one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $97. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Portland to South Carolina for a low price.

  • What are the most popular routes from Portland to South Carolina?

  • Can I find deals for flights from Portland to South Carolina that include hotel bookings?

    Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.

  • Can I find deals for business class flights from Portland to South Carolina?

    Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Portland to South Carolina (average of $217). Flying from Portland to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Portland to South Carolina

Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$258Average$464FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$273Average$573FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$274Average$495FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$284Average$517FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$354Average$543FlexibilityNo cancel feeOn-time63%

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