$91+ Cheap flights from Portland (PDX) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
Apr 12 — Apr 191
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Portland to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to South CarolinaExplore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:58 am
PDX
- CLT
1 stop27h 56m
Frontier
Tue 4/217:49 pm
CLT
- PDX
1 stop19h 03m
Frontier
Deal found 3/8![Frontier logo]()
$175
This CheapOair deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:38 pm
PDX
- CLT
1 stop27h 16m
Frontier
Tue 5/57:49 pm
CLT
- PDX
1 stop20h 13m
Frontier
Deal found 3/9![Frontier logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:38 pm
PDX
- CLT
2 stops31h 14m
Frontier
Sat 5/95:47 pm
CLT
- PDX
1 stop20h 16m
Frontier
Deal found 3/9![Frontier logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:05 pm
PDX
- CLT
2 stops46h 51m
Frontier
Sat 5/95:47 pm
CLT
- PDX
1 stop20h 16m
Frontier
Deal found 3/9![Frontier logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:58 am
PDX
- CLT
1 stop27h 56m
Frontier
Sat 4/185:51 pm
CLT
- PDX
1 stop19h 29m
Frontier
Deal found 3/11![Frontier logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:58 am
PDX
- CLT
2 stops18h 20m
Multiple Airlines
Tue 4/217:49 pm
CLT
- PDX
1 stop19h 03m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$230
This Booking.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:58 am
PDX
- CLT
1 stop27h 56m
Frontier
Fri 4/176:30 pm
CLT
- PDX
1 stop20h 12m
Frontier
Deal found 3/11![Frontier logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:58 am
PDX
- CLT
2 stops19h 59m
Frontier
Tue 4/147:49 pm
CLT
- PDX
1 stop18h 49m
Frontier
Deal found 3/10![Frontier logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:58 am
PDX
- CLT
2 stops19h 59m
Frontier
Sat 4/185:51 pm
CLT
- PDX
1 stop19h 29m
Frontier
Deal found 3/10![Frontier logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:48 am
PDX
- CLT
1 stop26h 08m
Frontier
Sat 5/95:47 pm
CLT
- PDX
1 stop20h 16m
Frontier
Deal found 3/9![Frontier logo]()
$242
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:05 am
PDX
- CHS
1 stop7h 54m
United Airlines
Sat 4/182:53 pm
CHS
- PDX
1 stop8h 49m
United Airlines
Deal found 3/12![United Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/44:06 pm
PDX
- CHS
1 stop25h 29m
Allegiant Air
Sat 6/138:48 pm
CHS
- PDX
1 stop20h 00m
Allegiant Air
Deal found 3/12![Allegiant Air logo]()
$291
Best flights from Portland to South CarolinaDiscover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
Discover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:05 pm
PDX
- CHS
2 stops11h 46m
Delta
Sat 5/26:25 am
CHS
- PDX
2 stops12h 13m
Delta
Deal found 3/8![Delta logo]()
$323
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:55 pm
PDX
- CHS
1 stop10h 22m
United Airlines
Mon 5/186:53 pm
CHS
- PDX
1 stop8h 02m
United Airlines
Deal found 3/8![United Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:30 am
PDX
- CLT
2 stops11h 15m
Southwest
Wed 5/61:45 pm
CLT
- PDX
2 stops11h 15m
Southwest
Deal found 3/9![Southwest logo]()
$369
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:23 pm
PDX
- AGS
1 stop9h 11m
American Airlines
Sat 4/253:03 pm
AGS
- PDX
1 stop9h 00m
American Airlines
Deal found 3/9![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:59 pm
PDX
- MYR
1 stop7h 19m
United Airlines
Tue 4/283:15 pm
MYR
- PDX
1 stop10h 19m
United Airlines
Deal found 3/12![United Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:05 pm
PDX
- CHS
2 stops11h 46m
Delta
Tue 4/215:20 am
CHS
- PDX
2 stops10h 29m
Delta
Deal found 3/8![Delta logo]()
$370
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:55 pm
PDX
- GSP
2 stops10h 15m
Southwest
Wed 6/35:05 pm
GSP
- PDX
2 stops9h 05m
Southwest
Deal found 3/9![Southwest logo]()
$377
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:59 pm
PDX
- GSP
1 stop6h 47m
United Airlines
Wed 4/155:41 pm
GSP
- PDX
1 stop7h 53m
United Airlines
Deal found 3/10![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:40 am
PDX
- MYR
1 stop7h 53m
American Airlines
Wed 4/224:52 pm
MYR
- PDX
1 stop8h 57m
American Airlines
Deal found 3/8![American Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1011:00 pm
PDX
- CAE
1 stop7h 25m
Delta
Tue 7/212:59 pm
CAE
- PDX
1 stop10h 04m
Delta
Deal found 3/9![Delta logo]()
$371
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:55 pm
PDX
- SAV
1 stop8h 00m
Southwest
Tue 5/122:20 pm
SAV
- PDX
2 stops11h 40m
Southwest
Deal found 3/8![Southwest logo]()
$378
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:30 pm
PDX
- CAE
1 stop7h 26m
United Airlines
Tue 7/145:27 pm
CAE
- PDX
1 stop9h 26m
United Airlines
Deal found 3/9![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:55 pm
PDX
- SAV
2 stops10h 45m
Southwest
Tue 4/142:20 pm
SAV
- PDX
2 stops11h 50m
Southwest
Deal found 3/12![Southwest logo]()
$383
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:15 pm
PDX
- GSP
2 stops9h 54m
Delta
Sat 4/185:40 am
GSP
- PDX
1 stop8h 01m
Delta
Deal found 3/11![Delta logo]()
$402
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:14 pm
PDX
- GSP
2 stops11h 41m
United Airlines
Wed 4/85:41 pm
GSP
- PDX
1 stop7h 53m
United Airlines
Deal found 3/11![United Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/279:47 pm
PDX
- AGS
1 stop7h 42m
American Airlines
Wed 6/34:00 pm
AGS
- PDX
1 stop9h 53m
American Airlines
Deal found 3/11![American Airlines logo]()
$470
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:10 am
PDX
- CHS
2 stops11h 10m
Southwest
Sun 5/316:55 pm
CHS
- PDX
1 stop8h 10m
Southwest
Deal found 3/8![Southwest logo]()
$402
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:55 pm
PDX
- AGS
1 stop7h 21m
Delta
Sat 4/255:40 am
AGS
- PDX
2 stops10h 09m
Delta
Deal found 3/8![Delta logo]()
$404
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/610:56 pm
PDX
- SAV
1 stop8h 20m
United Airlines
Tue 4/147:00 am
SAV
- PDX
1 stop8h 34m
United Airlines
Deal found 3/12![United Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:10 am
PDX
- SAV
2 stops10h 10m
Southwest
Sat 5/165:20 pm
SAV
- PDX
1 stop7h 45m
Southwest
Deal found 3/11![Southwest logo]()
$403
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:47 pm
PDX
- AGS
1 stop7h 42m
American Airlines
Sat 6/64:00 pm
AGS
- PDX
1 stop8h 38m
American Airlines
Deal found 3/13![American Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:03 pm
PDX
- CAE
2 stops12h 42m
United Airlines
Sat 5/305:27 pm
CAE
- PDX
1 stop9h 26m
United Airlines
Deal found 3/10![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:05 am
PDX
- MYR
2 stops13h 59m
Delta
Wed 4/2212:05 pm
MYR
- PDX
2 stops12h 37m
Delta
Deal found 3/9![Delta logo]()
$415
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:30 pm
PDX
- CHS
1 stop7h 46m
United Airlines
Fri 6/1211:31 am
CHS
- PDX
1 stop10h 16m
United Airlines
Deal found 3/9![United Airlines logo]()
$375
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:10 am
PDX
- CLT
1 stop13h 50m
Southwest
Sat 5/238:10 am
CLT
- PDX
1 stop7h 25m
Southwest
Deal found 3/8![Southwest logo]()
$413
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:40 am
PDX
- GSP
1 stop6h 45m
Delta
Mon 9/73:42 pm
GSP
- PDX
2 stops10h 59m
Delta
Deal found 3/8![Delta logo]()
$417
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:51 am
PDX
- CHS
1 stop7h 57m
United Airlines
Thu 7/2311:31 am
CHS
- PDX
1 stop10h 16m
United Airlines
Deal found 3/10![United Airlines logo]()
$375
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:40 am
PDX
- CLT
1 stop12h 15m
Southwest
Sat 5/238:10 am
CLT
- PDX
1 stop7h 25m
Southwest
Deal found 3/8![Southwest logo]()
$413
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:06 pm
PDX
- CHS
1 stop6h 53m
Delta
Fri 6/56:00 am
CHS
- PDX
1 stop8h 46m
Delta
Deal found 3/12![Delta logo]()
$425
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:59 pm
PDX
- GSP
1 stop6h 48m
United Airlines
Sat 5/26:36 am
GSP
- PDX
2 stops11h 21m
United Airlines
Deal found 3/12![United Airlines logo]()
$378
Last-minute flights from Portland to South CarolinaDiscover last-minute flight deals from Portland to South Carolina. Data last updated March 13, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to South Carolina. Data last updated March 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:58 am
PDX
- CLT
2 stops19h 59m
Frontier
Tue 4/147:49 pm
CLT
- PDX
1 stop18h 49m
Frontier
Deal found 3/10![Frontier logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:58 am
PDX
- CLT
2 stops19h 59m
Frontier
Sat 4/185:51 pm
CLT
- PDX
1 stop19h 29m
Frontier
Deal found 3/10![Frontier logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:58 am
PDX
- CLT
1 stop27h 56m
Frontier
Tue 4/217:49 pm
CLT
- PDX
1 stop19h 03m
Frontier
Deal found 3/8![Frontier logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:58 am
PDX
- CLT
1 stop27h 56m
Frontier
Sat 4/185:51 pm
CLT
- PDX
1 stop19h 29m
Frontier
Deal found 3/11![Frontier logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:58 am
PDX
- CLT
2 stops18h 20m
Multiple Airlines
Tue 4/217:49 pm
CLT
- PDX
1 stop19h 03m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$230
This Booking.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:58 am
PDX
- CLT
1 stop27h 56m
Frontier
Fri 4/176:30 pm
CLT
- PDX
1 stop20h 12m
Frontier
Deal found 3/11![Frontier logo]()
$233
This Booking.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:58 am
PDX
- CLT
1 stop27h 56m
Frontier
Thu 4/166:18 pm
CLT
- PDX
1 stop19h 45m
Frontier
Deal found 3/10![Frontier logo]()
$243
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:05 am
PDX
- CHS
1 stop7h 54m
United Airlines
Sat 4/182:53 pm
CHS
- PDX
1 stop8h 49m
United Airlines
Deal found 3/12![United Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:28 pm
PDX
- CHS
1 stop9h 06m
American Airlines
Sat 4/182:59 pm
CHS
- PDX
1 stop9h 04m
American Airlines
Deal found 3/11![American Airlines logo]()
$295
This CheapOair deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:38 pm
PDX
- CLT
1 stop27h 16m
Frontier
Tue 5/57:49 pm
CLT
- PDX
1 stop20h 13m
Frontier
Deal found 3/9![Frontier logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:38 pm
PDX
- CLT
2 stops31h 14m
Frontier
Sat 5/95:47 pm
CLT
- PDX
1 stop20h 16m
Frontier
Deal found 3/9![Frontier logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:05 pm
PDX
- CLT
2 stops46h 51m
Frontier
Sat 5/95:47 pm
CLT
- PDX
1 stop20h 16m
Frontier
Deal found 3/9![Frontier logo]()
$227
One-way flights from Portland to South CarolinaSearch for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
Search for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:38 pm
PDX
- CLT
1 stop27h 16m
Frontier
Deal found 3/12![Frontier logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:48 pm
PDX
- CLT
1 stop26h 06m
Frontier
Deal found 3/13![Frontier logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:48 am
PDX
- CLT
1 stop26h 04m
Frontier
Deal found 3/9![Frontier logo]()
$100
This Booking.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:15 am
PDX
- CLT
1 stop27h 08m
Frontier
Deal found 3/10![Frontier logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:44 pm
PDX
- SAV
1 stop29h 53m
Allegiant Air
Deal found 3/8![Allegiant Air logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:48 am
PDX
- CLT
1 stop28h 06m
Frontier
Deal found 3/10![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:44 pm
PDX
- SAV
1 stop29h 54m
Allegiant Air
Deal found 3/9![Allegiant Air logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:27 pm
PDX
- CLT
1 stop27h 27m
Frontier
Deal found 3/9![Frontier logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:45 pm
PDX
- CLT
2 stops27h 09m
Frontier
Deal found 3/8![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:27 pm
PDX
- CLT
2 stops17h 45m
Frontier
Deal found 3/8![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:48 pm
PDX
- CLT
2 stops22h 48m
Frontier
Deal found 3/9![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:44 pm
PDX
- SAV
1 stop29h 54m
Allegiant Air
Deal found 3/11![Allegiant Air logo]()
$137
Find flight deals from Portland to South Carolina
Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated March 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $175 (Kiwi.com) |
One-way from | $91 (Kiwi.com) |
Popular in | April |
Cheapest in | January |
Average price | $475 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Mon 4/27
6:05 pm-8:51 am
2 stops11h 46m
Charleston
Sat 5/2
6:25 am-3:38 pm
2 stops12h 13m
$323
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Thu 5/14
10:55 pm-12:17 pm
1 stop10h 22m
Charleston
Mon 5/18
6:53 pm-11:55 pm
1 stop8h 02m
$355
PortlandMyrtle Beach
PDX - MYR
PDXMYR
Portland
Tue 4/21
11:59 pm-10:18 am
1 stop7h 19m
Myrtle Beach Intl
Tue 4/28
3:15 pm-10:34 pm
1 stop10h 19m
$367
Quickest round-trip
PortlandGreenville
PDX - GSP
PDXGSP
Portland
Wed 4/8
11:59 pm-9:46 am
1 stop6h 47m
Greenville
Wed 4/15
5:41 pm-10:34 pm
1 stop7h 53m
$367
PortlandCharlotte
PDX - CLT
PDXCLT
Portland
Tue 4/28
6:30 am-8:45 pm
2 stops11h 15m
Charlotte Douglas
Wed 5/6
1:45 pm-10:00 pm
2 stops11h 15m
$369
PortlandColumbia
PDX - CAE
PDXCAE
Portland
Sat 6/6
11:30 pm-9:56 am
1 stop7h 26m
Columbia Metropolitan
Tue 7/14
5:27 pm-11:53 pm
1 stop9h 26m
$369
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Mon 4/13
6:05 pm-8:51 am
2 stops11h 46m
Charleston
Tue 4/21
5:20 am-12:49 pm
2 stops10h 29m
$370
PortlandColumbia
PDX - CAE
PDXCAE
Portland
Fri 7/10
11:00 pm-9:25 am
1 stop7h 25m
Columbia Metropolitan
Tue 7/21
2:59 pm-10:03 pm
1 stop10h 04m
$371
PortlandGreenville
PDX - GSP
PDXGSP
Portland
Wed 4/1
7:14 pm-9:55 am
2 stops11h 41m
Greenville
Wed 4/8
5:41 pm-10:34 pm
1 stop7h 53m
$372
PortlandSavannah
PDX - SAV
PDXSAV
Portland
Mon 4/6
10:56 pm-10:16 am
1 stop8h 20m
Savannah/Hilton Head
Tue 4/14
7:00 am-12:34 pm
1 stop8h 34m
$373
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Portland to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
PDX-CLT
PDX-CHS
PDX-SAV
PDX-GSP
PDX-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to South Carolina
PDX-USSC
PDX-CLT
PDX-CHS
PDX-SAV
PDX-GSP
What is the cheapest month to book a flight from Portland to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Portland to South Carolina (average of $171). Flying from Portland to South Carolina in March is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PDX to SC?
Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 13, 2026.
One of the essential ways to save on airfare from Portland to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 43% on airfare.
What is the cheapest day to fly from Portland to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Portland to South Carolina. Price data was last updated on March 30, 2025.
Travelers seeking maximum savings on their Portland to South Carolina flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 13, 2026.
See what other customers who have flown with Alaska Airlines,Southwest, andDelta from Portland to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Food
7.1
Comfort
7.8
Overall
8.0
Entertainment
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Crew
8.5
Boarding
8.1
Food
7.1
Comfort
7.8
Overall
8.0
Entertainment
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Crew
8.5
Boarding
8.1
Food
7.1
Comfort
7.8
Overall
8.0
Entertainment
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Crew
8.5
Boarding
8.1
Food
7.1
Comfort
7.8
Overall
8.0
Entertainment
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Crew
8.5
Boarding
8.1
Food
7.1
Comfort
7.8
Overall
8.0
Entertainment
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Crew
8.5
Boarding
8.1
Food
7.1
Comfort
7.8
Overall
8.0
Entertainment
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Related info for your journey
Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Portland to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to South Carolina by cabin class
Find flights from Portland to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and South Carolina flights
Browse other Portland and South Carolina flight options. Last updated on March 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to South Carolina flights
Consider these flights traveling from Portland to South Carolina.
Top 5 airlines flying from Portland to South Carolina
Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$162 | Average$440 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$266 | Average$452 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$284 | Average$530 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$298 | Average$525 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$329 | Average$540 | FlexibilityNo cancel fee | On-time63% |