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South Carolina

$108+ Cheap flights from Portland (PDX) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Portland to South Carolina

Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Booking.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:47 pmPDX - CLT
1 stop19h 35mFrontier
Sat 1/37:32 pmCLT - PDX
1 stop19h 11mFrontier
Deal found 12/10$382
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:52 pmPDX - SAV
1 stop8h 51mUnited Airlines
Sat 1/102:05 pmSAV - PDX
1 stop10h 44mUnited Airlines
Deal found 12/10$437
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:52 pmPDX - SAV
1 stop8h 51mUnited Airlines
Tue 1/136:40 amSAV - PDX
2 stops15h 16mUnited Airlines
Deal found 12/10$442
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:52 pmPDX - SAV
1 stop8h 51mUnited Airlines
Mon 1/123:28 pmSAV - PDX
1 stop10h 25mUnited Airlines
Deal found 12/10$450
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:59 pmPDX - CLT
Nonstop4h 51mAmerican Airlines
Wed 12/316:15 pmCLT - PDX
1 stop9h 44mAmerican Airlines
Deal found 12/10$466
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:52 pmPDX - SAV
1 stop8h 51mUnited Airlines
Sun 1/113:54 pmSAV - PDX
1 stop20h 51mUnited Airlines
Deal found 12/10$476
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1110:15 pmPDX - CLT
Nonstop4h 44mAmerican Airlines
Sat 12/136:26 pmCLT - PDX
Nonstop5h 41mAmerican Airlines
Deal found 12/11$483
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/137:00 amPDX - CLT
1 stop7h 05mUnited Airlines
Thu 12/186:22 amCLT - PDX
1 stop9h 58mUnited Airlines
Deal found 12/10$498
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:15 amPDX - CLT
1 stop7h 10mDelta
Sat 12/136:00 amCLT - PDX
1 stop7h 44mDelta
Deal found 12/10$503
This Southwest deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:00 amPDX - CLT
2 stops10h 10mSouthwest
Mon 12/225:45 amCLT - PDX
2 stops14h 05mSouthwest
Deal found 12/10$506
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1110:15 pmPDX - CLT
Nonstop4h 44mAmerican Airlines
Mon 12/155:19 amCLT - PDX
1 stop8h 45mAmerican Airlines
Deal found 12/11$513
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/188:35 amPDX - CLT
1 stop10h 14mAmerican Airlines
Tue 12/236:38 pmCLT - PDX
Nonstop5h 41mAmerican Airlines
Deal found 12/11$515

Find flight deals from Portland to South Carolina

Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$230
(Kiwi.com)

One-way from

$108
(Kiwi.com)

Popular in

March

Cheapest in

February

Average price

$542
Provider with most accurate pricing for Portland-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Myrtle Beach Intl flights.
Search Deals
From Portland to South Carolina
Search Deals
One-way flight from Portland to South Carolina
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Portland

Fly to

South Carolina

Route

Depart

Return

Price

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Thu 1/15

5:00 am-3:05 pm

1 stop7h 05m

Charleston

Sat 1/31

1:13 pm-6:56 pm

1 stop8h 43m

$276

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Thu 1/15

6:30 am-8:55 pm

2 stops11h 25m

Charleston

Sat 1/31

9:00 am-8:50 pm

2 stops14h 50m

$286

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Mon 2/2

11:01 pm-6:40 pm

1 stop16h 39m

Charleston

Wed 2/4

10:18 am-8:27 pm

2 stops13h 09m

$294

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Mon 3/2

6:00 am-5:32 pm

1 stop8h 32m

Charleston

Wed 3/4

6:32 pm-11:44 pm

1 stop8h 12m

$304

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Tue 2/3

7:00 am-8:02 pm

1 stop10h 02m

Charleston

Thu 2/5

4:41 pm-10:32 pm

1 stop8h 51m

$305

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Sat 1/17

6:50 am-4:53 pm

1 stop7h 03m

Greenville

Tue 1/20

10:06 am-8:40 pm

2 stops13h 34m

$312

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Sat 1/17

6:00 am-7:07 pm

2 stops10h 07m

Greenville

Tue 1/20

6:25 am-11:45 am

1 stop8h 20m

$312

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Mon 2/2

5:00 pm-9:26 am

2 stops13h 26m

Charleston

Wed 2/4

9:00 am-8:40 pm

2 stops14h 40m

$315

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Fri 1/23

12:35 pm-10:34 pm

1 stop6h 59m

Charleston

Mon 1/26

2:37 pm-8:24 pm

1 stop8h 47m

$335

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Fri 1/30

9:45 pm-9:26 am

1 stop8h 41m

Charleston

Mon 2/2

5:18 pm-10:15 pm

1 stop7h 57m

$335

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 60 results
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Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

What is the cheapest month to book a flight from Portland to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Portland to South Carolina (average of $183). Flying from Portland to South Carolina in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to SC?

Find hourly flight availability from Portland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from Portland to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 26% on airfare.

What is the cheapest day to fly from Portland to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Portland to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Portland to South Carolina flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 12, 2025.
See what other customers who have flown with Alaska Airlines, Southwest, and Delta from Portland to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,432 reviews

Entertainment

7.0

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Comfort

7.8

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.
Alaska Airlines
8.0
Very good
11,432 reviews
Alaska Airlines
8.0
Very good
11,432 reviews

Entertainment

7.0

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Comfort

7.8

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.
Southwest
7.9
Good
4,253 reviews
Alaska Airlines
8.0
Very good
11,432 reviews

Entertainment

7.0

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Comfort

7.8

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.
Delta
7.9
Good
8,008 reviews
Alaska Airlines
8.0
Very good
11,432 reviews

Entertainment

7.0

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Comfort

7.8

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.
United Airlines
7.4
Good
9,095 reviews
Alaska Airlines
8.0
Very good
11,432 reviews

Entertainment

7.0

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Comfort

7.8

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.
American Airlines
7.2
Good
11,050 reviews
Alaska Airlines
8.0
Very good
11,432 reviews

Entertainment

7.0

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Comfort

7.8

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.

Related info for your journey

Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to South Carolina?

    Portland (PDX), located 6.0 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.

  • How long is the flight from Portland to South Carolina?

    There are many flights that can get you from Portland to South Carolina in 7h 05m. Fly via United Airlines, Delta, or American Airlines to get the fastest option. The distance between Portland and South Carolina is about 2405 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Portland to South Carolina one-way?

    The cheapest airline one-way is Alaska Airlines, with whom users have recently found tickets for as low as $126. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Portland to South Carolina for a low price.

  • What are the most popular routes from Portland to South Carolina?

    While some choose either Portland - Charleston or Portland - Savannah/Hilton Head, Portland - Charlotte Douglas is the most popular route from Portland to South Carolina.

  • Can I find deals for flights from Portland to South Carolina that include hotel bookings?

    Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.

  • Can I find deals for business class flights from Portland to South Carolina?

    Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Portland to South Carolina (average of $183). Flying from Portland to South Carolina in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Portland to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Portland to South Carolina

Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$455FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$273Average$431FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$274Average$454FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$284Average$529FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$366Average$525FlexibilityNo cancel feeOn-time63%

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