$207+ Cheap flights from Midland (MAF) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — CHS
Nov 5 — Nov 121
Round-trip
1 adult, Economy
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Find cheap flights from Midland to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Midland to South Carolina
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Cheapest flights from Midland to South CarolinaExplore the most affordable flight options available from Midland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 6, 2026.
Explore the most affordable flight options available from Midland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 6, 2026.
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:50 am -
2 stops7h 20m
Tue 11/107:05 am -
2 stops7h 55m
Deal found 10/5![Southwest logo]()
$299
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
1 stop6h 33m
Tue 11/105:17 pm -
1 stop6h 37m
Deal found 10/4![American Airlines logo]()
$453
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:13 am -
1 stop6h 26m
Wed 11/113:29 pm -
1 stop7h 03m
Deal found 10/4![American Airlines logo]()
$457
This Southwest deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:00 am -
2 stops7h 35m
Wed 11/1111:00 am -
2 stops7h 40m
Deal found 10/4![Southwest logo]()
$467
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:00 am -
2 stops11h 11m
Wed 11/1811:27 am -
2 stops13h 16m
Deal found 10/1![United Airlines logo]()
$475
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/223:10 pm -
2 stops7h 10m
Sun 2/216:15 am -
2 stops9h 30m
Deal found 10/2![Southwest logo]()
$476
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:13 am -
1 stop5h 07m
Mon 11/95:10 pm -
1 stop7h 42m
Deal found 10/4![American Airlines logo]()
$477
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/213:10 pm -
2 stops7h 10m
Mon 12/286:45 am -
2 stops8h 45m
Deal found 10/5![Southwest logo]()
$513
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/205:00 am -
2 stops10h 54m
Fri 2/266:30 am -
2 stops10h 45m
Deal found 10/6![United Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/222:27 pm -
1 stop6h 22m
Sun 2/217:00 am -
1 stop5h 27m
Deal found 10/2![United Airlines logo]()
$731
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:03 am -
1 stop7h 27m
Mon 11/95:10 pm -
1 stop7h 42m
Deal found 10/4![American Airlines logo]()
$830
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:16 pm -
2 stops8h 37m
Mon 11/95:10 pm -
1 stop7h 42m
Deal found 10/4![American Airlines logo]()
$835
Best flights from Midland to South CarolinaDiscover carefully curated flight deals from Midland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 6, 2026.
Discover carefully curated flight deals from Midland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 6, 2026.
This Southwest deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:50 am -
2 stops7h 20m
Tue 11/107:05 am -
2 stops7h 55m
Deal found 10/4![Southwest logo]()
$447
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
1 stop6h 33m
Tue 11/105:17 pm -
1 stop6h 37m
Deal found 10/4![American Airlines logo]()
$453
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:00 am -
2 stops11h 11m
Wed 11/1811:27 am -
2 stops13h 16m
Deal found 10/1![United Airlines logo]()
$475
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:13 am -
1 stop6h 26m
Wed 11/113:29 pm -
1 stop7h 03m
Deal found 10/4![American Airlines logo]()
$457
This Southwest deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:00 am -
2 stops7h 35m
Wed 11/1111:00 am -
2 stops7h 40m
Deal found 10/4![Southwest logo]()
$467
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/47:25 am -
2 stops9h 30m
Wed 3/101:25 pm -
1 stop9h 35m
Deal found 10/5![Southwest logo]()
$468
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/223:10 pm -
2 stops7h 10m
Sun 2/216:15 am -
2 stops9h 30m
Deal found 10/2![Southwest logo]()
$476
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:38 pm -
2 stops9h 19m
Mon 11/95:10 pm -
1 stop7h 42m
Deal found 10/4![American Airlines logo]()
$569
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/205:00 am -
2 stops10h 54m
Fri 2/266:30 am -
2 stops10h 45m
Deal found 10/6![United Airlines logo]()
$657
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/213:10 pm -
2 stops7h 10m
Mon 12/286:45 am -
2 stops8h 45m
Deal found 10/5![Southwest logo]()
$513
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/222:27 pm -
1 stop6h 22m
Sun 2/217:00 am -
1 stop5h 27m
Deal found 10/2![United Airlines logo]()
$731
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:00 am -
3 stops11h 08m
Mon 11/92:52 pm -
2 stops9h 51m
Deal found 10/4![United Airlines logo]()
$1,283
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:41 am -
3 stops10h 21m
Mon 11/92:52 pm -
2 stops9h 51m
Deal found 10/4![United Airlines logo]()
$1,423
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:41 am -
2 stops8h 27m
Mon 11/910:16 am -
3 stops12h 42m
Deal found 10/4![United Airlines logo]()
$1,527
Last-minute flights from Midland to South CarolinaDiscover last-minute flight deals from Midland to South Carolina. Data last updated October 6, 2026 and is based on user searches.
Discover last-minute flight deals from Midland to South Carolina. Data last updated October 6, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:00 am -
2 stops10h 57m
Fri 10/2310:22 am -
2 stops12h 36m
Deal found 10/4![United Airlines logo]()
$1,067
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:50 am -
2 stops7h 20m
Tue 11/107:05 am -
2 stops7h 55m
Deal found 10/5![Southwest logo]()
$299
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
1 stop6h 33m
Tue 11/105:17 pm -
1 stop6h 37m
Deal found 10/4![American Airlines logo]()
$453
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:13 am -
1 stop5h 07m
Mon 11/95:10 pm -
1 stop7h 42m
Deal found 10/4![American Airlines logo]()
$477
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:00 am -
3 stops11h 08m
Mon 11/92:52 pm -
2 stops9h 51m
Deal found 10/4![United Airlines logo]()
$1,283
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:03 am -
1 stop7h 27m
Mon 11/95:10 pm -
1 stop7h 42m
Deal found 10/4![American Airlines logo]()
$830
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:16 pm -
2 stops8h 37m
Mon 11/95:10 pm -
1 stop7h 42m
Deal found 10/4![American Airlines logo]()
$835
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:41 am -
3 stops10h 21m
Mon 11/92:52 pm -
2 stops9h 51m
Deal found 10/4![United Airlines logo]()
$1,423
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:13 am -
1 stop6h 26m
Wed 11/113:29 pm -
1 stop7h 03m
Deal found 10/4![American Airlines logo]()
$457
This Southwest deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:00 am -
2 stops7h 35m
Wed 11/1111:00 am -
2 stops7h 40m
Deal found 10/4![Southwest logo]()
$467
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:00 am -
2 stops11h 11m
Wed 11/1811:27 am -
2 stops13h 16m
Deal found 10/1![United Airlines logo]()
$475
One-way flights from Midland to South CarolinaSearch for one-way flight options from Midland to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 6, 2026.
Search for one-way flight options from Midland to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 6, 2026.
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:00 am -
1 stop7h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![American Airlines logo]()
$207
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:55 am -
1 stop7h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![American Airlines logo]()
$229
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:00 am -
2 stops8h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![United Airlines logo]()
$234
Find flight deals from Midland to South Carolina
Keep the following information in mind while searching for Midland to South Carolina flight deals. Data was last updated October 6, 2026.
Round-trip from | $299 (Southwest) |
|---|---|
One-way from | $207 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Midland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 6, 2026.
Use the filters below to find and compare flights from Midland to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
MidlandGreenville
MAF Midland Intl - GSP Greenville
MAFGSP
Midland Intl
Sat 10/24
5:00 am-1:28 pm
1 stop7h 28m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$207
MidlandGreenville
MAF Midland Intl - GSP Greenville
MAFGSP
Midland Intl
Sun 10/25
7:55 am-4:35 pm
1 stop7h 40m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$229
MidlandGreenville
MAF Midland Intl - GSP Greenville
MAFGSP
Midland Intl
Sun 10/25
5:00 am-2:16 pm
2 stops8h 16m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$234
MidlandGreenville
MAF Midland Intl - GSP Greenville
MAFGSP
Midland Intl
Tue 11/3
5:50 am-2:10 pm
2 stops7h 20m
Greenville
Tue 11/10
7:05 am-2:00 pm
2 stops7h 55m
$447
MidlandGreenville
MAF Midland Intl - GSP Greenville
MAFGSP
Midland Intl
Tue 11/3
6:00 am-1:33 pm
1 stop6h 33m
Greenville
Tue 11/10
5:17 pm-10:54 pm
1 stop6h 37m
$453
MidlandCharleston
MAF Midland Intl - CHS Charleston
MAFCHS
Midland Intl
Tue 11/10
7:13 am-2:39 pm
1 stop6h 26m
Charleston
Wed 11/11
3:29 pm-9:32 pm
1 stop7h 03m
$457
MidlandCharleston
MAF Midland Intl - CHS Charleston
MAFCHS
Midland Intl
Tue 11/10
11:00 am-7:35 pm
2 stops7h 35m
Charleston
Wed 11/11
11:00 am-5:40 pm
2 stops7h 40m
$467
MidlandCharleston
MAF Midland Intl - CHS Charleston
MAFCHS
Midland Intl
Thu 3/4
7:25 am-5:55 pm
2 stops9h 30m
Charleston
Wed 3/10
1:25 pm-10:00 pm
1 stop9h 35m
$468
MidlandMyrtle Beach
MAF Midland Intl - MYR Myrtle Beach Intl
MAFMYR
Midland Intl
Tue 11/17
5:00 am-5:11 pm
2 stops11h 11m
Myrtle Beach Intl
Wed 11/18
11:27 am-11:43 pm
2 stops13h 16m
$475
MidlandGreenville
MAF Midland Intl - GSP Greenville
MAFGSP
Midland Intl
Tue 12/22
3:10 pm-11:20 pm
2 stops7h 10m
Greenville
Sun 2/21
6:15 am-2:45 pm
2 stops9h 30m
$476
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Midland to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Midland with our price prediction graph.
MAF-GSP
MAF-CHS
MAF-MYR
MAF-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Midland to South Carolina
MAF-USSC
MAF-GSP
MAF-CHS
MAF-MYR
MAF-CAE
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 6, 2026.
Peruse reviews from past customers who have flown with Southwest and American Airlines from Midland to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Comfort
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Comfort
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Midland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Midland to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Midland to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Midland and South Carolina flights
Browse other Midland and South Carolina flight options. Last updated on October 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Midland to South Carolina flights
Consider these flights traveling from Midland to South Carolina.
Top 2 airlines flying from Midland to South Carolina
Discover the top 2 airlines that operate flights from Midland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$372 | Average$390 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$540 | Average$817 | FlexibilityNo cancel fee | On-time71% |