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$393+ Cheap flights from Madrid, Spain (MAD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/17. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — CHS
Jun 24 — Jul 11
Wed 6/24
Wed 7/1
1 adult, Economy
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Cheap flight deals from Madrid to South Carolina

Cheapest flights from Madrid to South Carolina
Explore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 25, 2026.

This Flighttix deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/62:05 pm
MAD
-
CHS
1 stop26h 54m
JetBlue
Thu 6/116:45 pm
CHS
-
MAD
1 stop10h 45m
JetBlue
Deal found 5/23$806
This eDestinos deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/112:40 pm
MAD
-
CLT
Nonstop9h 30m
Iberia
Mon 2/16:25 pm
CLT
-
MAD
1 stop13h 50m
Iberia
Deal found 5/23$828
This KAYAK deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:05 pm
MAD
-
SAV
1 stop25h 44m
JetBlue
Thu 6/189:18 am
SAV
-
MAD
1 stop20h 12m
JetBlue
Deal found 5/21$831
This eDestinos deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:00 am
MAD
-
CLT
1 stop14h 16m
Virgin Atlantic
Mon 2/111:45 am
CLT
-
MAD
2 stops14h 15m
Virgin Atlantic
Deal found 5/23$839
This Rumbo deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:30 pm
MAD
-
CLT
2 stops33h 32m
Scandinavian Airlines
Fri 10/236:00 am
CLT
-
MAD
2 stops23h 55m
Scandinavian Airlines
Deal found 5/24$857
This lol.travel deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:05 pm
MAD
-
CHS
1 stop26h 54m
JetBlue
Mon 6/152:02 pm
CHS
-
MAD
1 stop15h 28m
JetBlue
Deal found 5/24$864
This lol.travel deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/92:05 pm
MAD
-
CHS
1 stop26h 54m
JetBlue
Mon 6/156:45 pm
CHS
-
MAD
1 stop10h 45m
JetBlue
Deal found 5/21$877
This lol.travel deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:05 pm
MAD
-
SAV
1 stop32h 58m
JetBlue
Fri 6/129:18 am
SAV
-
MAD
1 stop20h 12m
JetBlue
Deal found 5/24$897
This Rumbo deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:35 pm
MAD
-
CLT
2 stops32h 27m
Scandinavian Airlines
Sun 9/134:30 pm
CLT
-
MAD
2 stops37h 30m
Scandinavian Airlines
Deal found 5/24$901
This lol.travel deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:05 pm
MAD
-
CHS
1 stop30h 59m
JetBlue
Mon 6/88:50 pm
CHS
-
MAD
1 stop32h 40m
JetBlue
Deal found 5/21$901
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:20 am
MAD
-
GSP
2 stops21h 09m
United Airlines
Sun 9/276:20 am
GSP
-
MAD
2 stops19h 45m
United Airlines
Deal found 5/23$903
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:05 am
MAD
-
CHS
2 stops23h 47m
United Airlines
Mon 6/82:47 pm
CHS
-
MAD
1 stop11h 18m
United Airlines
Deal found 5/21$903

Find flight deals from Madrid to South Carolina

Keep the following information in mind while searching for Madrid to South Carolina flight deals. Data was last updated May 25, 2026.

Round-trip from

$806
(Flighttix)

One-way from

$393
(Kiwi.com)
From Madrid Barajas to South Carolina
Search Deals
One-way flight from Madrid Barajas to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 25, 2026.
Use the filters below to find and compare flights from Madrid to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Thu 9/24

8:20 am-11:29 pm

2 stops21h 09m

Greenville

Sun 9/27

7:47 pm-8:05 am

1 stop30h 18m

$903

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Sat 6/6

10:50 am-11:34 pm

1 stop18h 44m

Greenville

Wed 6/10

7:40 pm-8:05 am

1 stop30h 25m

$909

MadridMyrtle Beach

MAD - MYR

MADMYR

Madrid Barajas

Wed 6/10

5:55 am-6:04 pm

2 stops18h 09m

Myrtle Beach Intl

Sun 6/14

11:24 am-8:50 am

2 stops15h 26m

$911

MadridMyrtle Beach

MAD - MYR

MADMYR

Madrid Barajas

Wed 6/10

10:25 am-10:37 am

2 stops30h 12m

Myrtle Beach Intl

Sun 6/14

12:38 pm-6:20 am

1 stop11h 42m

$912

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Mon 6/8

6:00 am-5:54 pm

2 stops17h 54m

Charleston

Mon 6/15

6:39 pm-4:25 pm

2 stops15h 46m

$913

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Sat 6/6

10:50 am-7:05 pm

2 stops14h 15m

Charleston

Thu 6/11

11:18 am-8:05 am

2 stops14h 47m

$917

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Sat 6/6

10:50 am-7:04 pm

2 stops14h 14m

Greenville

Wed 6/10

7:40 pm-8:05 am

1 stop30h 25m

$918

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Thu 9/17

11:15 am-7:35 pm

1 stop14h 20m

Savannah/Hilton Head

Mon 9/21

6:45 am-8:05 am

2 stops19h 20m

$918

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Fri 9/25

12:45 pm-2:17 pm

2 stops31h 32m

Charlotte Douglas

Sun 10/4

11:22 am-9:00 am

1 stop15h 38m

$948

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Wed 10/28

11:15 am-12:50 am

2 stops18h 35m

Charlotte Douglas

Sun 11/1

6:00 am-7:45 am

1 stop19h 45m

$958

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/24

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Madrid to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to South Carolina

What is the cheapest month to book a flight from Madrid to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $648). Flying from Madrid to South Carolina in July is currently the most expensive (average of $932). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Madrid to South Carolina?

Related info for your journey

Find useful and relevant information for your journey from Madrid to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madrid to South Carolina?

    Madrid Barajas (MAD) is the airport you will fly out of if you book a flight from Madrid to South Carolina. It is only a 8.5 mi journey to Barajas (MAD) from Madrid’s city center.

  • How long is the flight from Madrid to South Carolina?

    A quick flight from Madrid to South Carolina can take about 18h 44m. United Airlines provides one of the quickest options available for as low as $909. Madrid and South Carolina are separated by a distance of 4169 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madrid to South Carolina?

    When deciding which route to take from Madrid to South Carolina consider Madrid Barajas - Charlotte Douglas, Madrid Barajas - Charleston or Madrid Barajas - Savannah/Hilton Head as they are the most popular.

  • Can I find deals for flights from Madrid to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madrid to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to South Carolina.

  • Can I find deals for business class flights from Madrid to South Carolina?

    Yes. Cheapflights offers flight deals from Madrid to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $648). Flying from Madrid to South Carolina in July is currently the most expensive (average of $932). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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