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South Carolina

$314+ Cheap flights from Madrid, Spain (MAD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — CHS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Madrid to South Carolina

Keep the following information in mind while searching for Madrid to South Carolina flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$565
(United Airlines)

One-way from

$314
(Kiwi.com)
Provider with most accurate pricing for Madrid Barajas-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Madrid Barajas-Myrtle Beach Intl flights.
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From Madrid Barajas to South Carolina
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One-way flight from Madrid Barajas to South Carolina
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Find flight deals from Madrid to South Carolina

Cheapest flights from Madrid to South Carolina
Explore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amMAD - CLT
2 stops40h 55mUnited Airlines
Sat 11/1510:43 amCLT - MAD
2 stops39h 17mUnited Airlines
Deal found 10/30$565
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:35 pmMAD - CLT
3 stops34h 33mMultiple Airlines
Wed 11/195:45 amCLT - MAD
2 stops28h 25mMultiple Airlines
Deal found 10/30$604
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:00 pmMAD - CHS
2 stops25h 56mMultiple Airlines
Mon 11/177:00 amCHS - MAD
3 stops22h 00mMultiple Airlines
Deal found 10/30$604
This flugladen.de deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flugladen.de is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:10 amMAD - CLT
2 stops41h 47mMultiple Airlines
Wed 11/2610:13 amCLT - MAD
2 stops41h 07mMultiple Airlines
Deal found 10/30$644
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:00 amMAD - CLT
2 stops19h 10mMultiple Airlines
Mon 12/151:57 pmCLT - MAD
2 stops22h 48mMultiple Airlines
Deal found 10/29$735
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:30 pmMAD - MYR
2 stops31h 24mMultiple Airlines
Tue 11/259:22 amMYR - MAD
1 stop20h 03mMultiple Airlines
Deal found 10/29$769
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amMAD - CHS
2 stops23h 42mUnited Airlines
Mon 11/1711:25 amCHS - MAD
2 stops15h 50mUnited Airlines
Deal found 10/30$796
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:35 amMAD - SAV
2 stops21h 21mUnited Airlines
Tue 11/182:20 pmSAV - MAD
1 stop11h 45mUnited Airlines
Deal found 10/30$796
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:55 amMAD - CHS
2 stops19h 35mUnited Airlines
Wed 12/104:38 pmCHS - MAD
2 stops33h 27mUnited Airlines
Deal found 10/29$798
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:00 amMAD - MYR
2 stops29h 30mDelta
Tue 11/2511:29 amMYR - MAD
2 stops21h 51mDelta
Deal found 10/30$804
This KLM deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:00 amMAD - CHS
1 stop16h 32mKLM
Mon 11/1712:53 pmCHS - MAD
1 stop13h 07mKLM
Deal found 10/30$812
This KLM deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1410:00 amMAD - SAV
1 stop17h 19mKLM
Tue 11/183:08 pmSAV - MAD
1 stop12h 07mKLM
Deal found 10/30$812

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Madrid to South Carolina that are best for you.

Fly from

Madrid

Fly to

South Carolina

Route

Depart

Return

Price

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Thu 11/13

6:00 am-4:55 pm

2 stops40h 55m

Charlotte Douglas

Sat 11/15

10:43 am-8:00 am

2 stops39h 17m

$565

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 11/13

12:00 pm-7:56 am

2 stops25h 56m

Charleston

Mon 11/17

7:00 am-11:00 am

3 stops22h 00m

$604

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Fri 2/20

6:00 am-6:12 pm

2 stops18h 12m

Charleston

Tue 2/24

10:20 am-9:15 am

2 stops16h 55m

$756

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Fri 2/20

6:00 am-11:44 pm

2 stops23h 44m

Charleston

Tue 2/24

11:15 am-9:15 am

1 stop16h 00m

$763

MadridMyrtle Beach

MAD - MYR

MADMYR

Madrid Barajas

Thu 11/20

6:30 pm-7:54 pm

2 stops31h 24m

Myrtle Beach Intl

Tue 11/25

9:22 am-11:25 am

1 stop20h 03m

$769

MadridMyrtle Beach

MAD - MYR

MADMYR

Madrid Barajas

Thu 3/5

10:00 am-11:35 pm

2 stops19h 35m

Myrtle Beach Intl

Mon 3/9

6:45 pm-3:20 pm

2 stops15h 35m

$773

MadridMyrtle Beach

MAD - MYR

MADMYR

Madrid Barajas

Thu 3/5

11:15 am-11:35 pm

1 stop18h 20m

Myrtle Beach Intl

Mon 3/9

10:55 am-8:05 am

1 stop16h 10m

$777

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 11/13

6:00 am-11:42 pm

2 stops23h 42m

Charleston

Mon 11/17

11:25 am-9:15 am

2 stops15h 50m

$796

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Fri 11/14

8:35 am-11:56 pm

2 stops21h 21m

Savannah/Hilton Head

Tue 11/18

2:20 pm-8:05 am

1 stop11h 45m

$796

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Wed 12/3

5:55 am-7:30 pm

2 stops19h 35m

Charleston

Wed 12/10

7:47 pm-8:05 am

1 stop30h 18m

$798

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 53 results
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Best time to book a flight from Madrid to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to South Carolina

What is the cheapest month to book a flight from Madrid to South Carolina?

Currently, January is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $579). Flying from Madrid to South Carolina in July is currently the most expensive (average of $923). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Madrid to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madrid to South Carolina?

    Madrid Barajas (MAD) is the airport you will fly out of if you book a flight from Madrid to South Carolina. It is only a 8.5 mi journey to Barajas (MAD) from Madrid’s city center.

  • How long is the flight from Madrid to South Carolina?

    A quick flight from Madrid to South Carolina can take about 19h 35m. United Airlines provides one of the quickest options available for as low as $773. Madrid and South Carolina are separated by a distance of 4050 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madrid to South Carolina?

    When deciding which route to take from Madrid to South Carolina consider Madrid Barajas - Charlotte Douglas, Madrid Barajas - Charleston or Madrid Barajas - Myrtle Beach Intl as they are the most popular.

  • Can I find deals for flights from Madrid to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madrid to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to South Carolina.

  • Can I find deals for business class flights from Madrid to South Carolina?

    Yes. Cheapflights offers flight deals from Madrid to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $579). Flying from Madrid to South Carolina in July is currently the most expensive (average of $923). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Madrid to South Carolina

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