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South Carolina

$317+ Cheap flights from Madrid, Spain (MAD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — CHS
Apr 5 — Apr 121
Sun 4/5
Sun 4/12
1 adult, Economy
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Cheap flight deals from Madrid to South Carolina

Cheapest flights from Madrid to South Carolina
Explore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 6, 2026.

This Mytrip deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:10 pm
MAD
-
CLT
2 stops33h 49m
Multiple Airlines
Wed 4/2210:16 am
CLT
-
MAD
2 stops24h 44m
Multiple Airlines
Deal found 3/1$542
This Mytrip deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1610:20 am
MAD
-
CHS
3 stops29h 49m
Multiple Airlines
Mon 3/2312:04 pm
CHS
-
MAD
2 stops27h 16m
Multiple Airlines
Deal found 3/1$612
This Trip.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:40 am
MAD
-
CLT
2 stops35h 12m
Multiple Airlines
Mon 3/309:18 am
CLT
-
MAD
2 stops33h 02m
Multiple Airlines
Deal found 3/4$638
This JetBlue deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:30 pm
MAD
-
CHS
1 stop13h 53m
JetBlue
Wed 4/296:00 am
CHS
-
MAD
1 stop23h 30m
JetBlue
Deal found 3/5$655
This Mytrip deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:40 am
MAD
-
CLT
2 stops22h 19m
Multiple Airlines
Fri 4/249:32 pm
CLT
-
MAD
3 stops30h 33m
Multiple Airlines
Deal found 3/3$676
This Mytrip deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:55 am
MAD
-
CLT
3 stops22h 06m
Multiple Airlines
Sat 4/257:12 am
CLT
-
MAD
2 stops17h 38m
Multiple Airlines
Deal found 3/4$678
This Trip.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:55 am
MAD
-
CLT
1 stop18h 58m
Multiple Airlines
Mon 3/309:18 am
CLT
-
MAD
2 stops19h 12m
Multiple Airlines
Deal found 3/2$689
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:35 pm
MAD
-
CLT
1 stop14h 24m
Multiple Airlines
Mon 5/1110:16 am
CLT
-
MAD
2 stops45h 04m
Multiple Airlines
Deal found 3/4$697
This Mytrip deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/910:05 am
MAD
-
CLT
2 stops19h 48m
Multiple Airlines
Thu 4/2310:16 am
CLT
-
MAD
2 stops26h 24m
Multiple Airlines
Deal found 3/3$703
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/23:35 pm
MAD
-
CLT
1 stop14h 09m
Multiple Airlines
Mon 5/1110:16 am
CLT
-
MAD
2 stops45h 04m
Multiple Airlines
Deal found 3/4$709
This Mytrip deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:05 am
MAD
-
CLT
2 stops30h 40m
Multiple Airlines
Fri 4/246:30 am
CLT
-
MAD
2 stops32h 55m
Multiple Airlines
Deal found 3/3$712
This Trip.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:35 pm
MAD
-
MYR
1 stop21h 26m
Multiple Airlines
Thu 4/232:23 pm
MYR
-
MAD
1 stop17h 07m
Multiple Airlines
Deal found 3/2$721

Find flight deals from Madrid to South Carolina

Keep the following information in mind while searching for Madrid to South Carolina flight deals. Data was last updated March 6, 2026.

Round-trip from

$542
(Mytrip)

One-way from

$317
(Kiwi.com)
From Madrid Barajas to South Carolina
Search Deals
One-way flight from Madrid Barajas to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 6, 2026.
Use the filters below to find and compare flights from Madrid to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Mon 3/16

10:20 am-11:09 am

3 stops29h 49m

Charleston

Mon 3/23

12:04 pm-8:20 pm

2 stops27h 16m

$612

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 4/23

6:05 am-6:28 pm

2 stops18h 23m

Charleston

Wed 4/29

11:22 am-8:05 am

2 stops14h 43m

$799

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 4/23

6:05 am-6:28 pm

2 stops18h 23m

Charleston

Mon 4/27

8:00 am-9:00 am

2 stops19h 00m

$799

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Sat 4/18

5:55 am-6:11 pm

2 stops18h 16m

Savannah/Hilton Head

Sat 4/25

9:15 am-9:00 am

2 stops17h 45m

$799

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Fri 4/17

6:00 am-6:15 pm

2 stops18h 15m

Savannah/Hilton Head

Mon 4/27

9:50 am-8:05 am

1 stop16h 15m

$799

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Fri 4/3

6:00 am-10:16 am

2 stops34h 16m

Savannah/Hilton Head

Sun 4/12

5:40 am-8:05 am

1 stop20h 25m

$800

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Wed 4/8

5:55 am-8:47 pm

2 stops20h 52m

Greenville

Tue 7/7

6:00 am-8:05 am

2 stops20h 05m

$811

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Thu 4/16

6:05 am-8:47 pm

2 stops20h 42m

Greenville

Wed 7/15

10:49 am-8:05 am

2 stops15h 16m

$812

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Wed 4/15

5:55 am-7:19 pm

2 stops19h 24m

Savannah/Hilton Head

Wed 4/22

2:25 pm-8:05 am

1 stop11h 40m

$812

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Thu 4/9

6:05 am-11:59 pm

2 stops23h 54m

Savannah/Hilton Head

Sun 4/12

5:40 am-8:05 am

1 stop20h 25m

$812

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/2

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Madrid to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to South Carolina

What is the cheapest month to book a flight from Madrid to South Carolina?

Currently, March is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $680). Flying from Madrid to South Carolina in July is currently the most expensive (average of $923). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Madrid to South Carolina?

Related info for your journey

Find useful and relevant information for your journey from Madrid to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madrid to South Carolina?

    Madrid Barajas (MAD) is the airport you will fly out of if you book a flight from Madrid to South Carolina. It is only a 8.5 mi journey to Barajas (MAD) from Madrid’s city center.

  • How long is the flight from Madrid to South Carolina?

    A quick flight from Madrid to South Carolina can take about 12h 01m. United Airlines provides one of the quickest options available for as low as $820. Madrid and South Carolina are separated by a distance of 4169 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madrid to South Carolina?

    When deciding which route to take from Madrid to South Carolina consider Madrid Barajas - Charlotte Douglas, Madrid Barajas - Savannah/Hilton Head or Madrid Barajas - Charleston as they are the most popular.

  • Can I find deals for flights from Madrid to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madrid to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to South Carolina.

  • Can I find deals for business class flights from Madrid to South Carolina?

    Yes. Cheapflights offers flight deals from Madrid to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to South Carolina?

    Currently, March is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $680). Flying from Madrid to South Carolina in July is currently the most expensive (average of $923). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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