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South Carolina

$321+ Cheap flights from Madrid, Spain (MAD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — CHS
dic. 13 — dic. 201
sáb. 12/13
sáb. 12/20
1 adult, Economy
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Cheap flight deals from Madrid to South Carolina

Keep the following information in mind while searching for Madrid to South Carolina flight deals. Data was last updated noviembre 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$631
(Kiwi.com)

One-way from

$321
(Kiwi.com)
Provider with most accurate pricing for Madrid Barajas-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Madrid Barajas-Myrtle Beach Intl flights.
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From Madrid Barajas to South Carolina
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One-way flight from Madrid Barajas to South Carolina
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Find flight deals from Madrid to South Carolina

Cheapest flights from Madrid to South Carolina
Explore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/103:35 pmMAD - CLT
1 stop27h 27mMultiple Airlines
jue. 2/59:07 pmCLT - MAD
2 stops37h 23mMultiple Airlines
Deal found 11/11$631
This Trip.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2710:00 amMAD - CHS
1 stop27h 26mMultiple Airlines
lun. 12/18:31 amCHS - MAD
1 stop17h 29mMultiple Airlines
Deal found 11/12$692
This Mytrip deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/912:10 pmMAD - CLT
3 stops29h 54mMultiple Airlines
vie. 12/128:55 amCLT - MAD
3 stops26h 15mMultiple Airlines
Deal found 11/13$705
This Mytrip deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/1612:10 pmMAD - CLT
3 stops29h 54mMultiple Airlines
vie. 1/3011:12 amCLT - MAD
2 stops27h 43mMultiple Airlines
Deal found 11/11$775
This Mytrip deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1112:10 pmMAD - CLT
2 stops29h 54mMultiple Airlines
vie. 1/303:15 pmCLT - MAD
2 stops19h 55mMultiple Airlines
Deal found 11/11$776
This Mytrip deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1710:20 amMAD - CLT
3 stops30h 43mMultiple Airlines
jue. 1/89:21 amCLT - MAD
3 stops30h 09mMultiple Airlines
Deal found 11/13$783
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/116:00 amMAD - CLT
2 stops18h 50mLufthansa
vie. 1/306:50 pmCLT - MAD
1 stop22h 45mLufthansa
Deal found 11/11$792
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/265:55 amMAD - SAV
2 stops24h 01mUnited Airlines
dom. 11/309:45 amSAV - MAD
1 stop16h 20mUnited Airlines
Deal found 11/11$792
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2012:10 pmMAD - MYR
2 stops37h 44mMultiple Airlines
mar. 11/258:59 pmMYR - MAD
1 stop32h 26mMultiple Airlines
Deal found 11/11$798
This Mytrip deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/141:00 pmMAD - CLT
2 stops24h 47mMultiple Airlines
vie. 11/283:01 pmCLT - MAD
2 stops21h 04mMultiple Airlines
Deal found 11/13$799
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2711:15 amMAD - CHS
2 stops33h 54mUnited Airlines
lun. 12/17:45 pmCHS - MAD
1 stop30h 20mUnited Airlines
Deal found 11/11$808
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/2811:15 amMAD - SAV
1 stop18h 41mUnited Airlines
mar. 12/210:15 amSAV - MAD
2 stops17h 00mUnited Airlines
Deal found 11/12$809

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 13, 2025.
Use the filters below to find and compare flights from Madrid to South Carolina that are best for you.

Fly from

Madrid

Fly to

South Carolina

Route

Depart

Return

Price

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

jue. 11/27

10:00 am-7:26 am

1 stop27h 26m

Charleston

lun. 12/1

8:31 am-8:00 am

1 stop17h 29m

$692

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

mar. 2/3

1:15 pm-8:59 pm

1 stop13h 44m

Greenville

mar. 2/10

12:06 pm-8:55 am

2 stops14h 49m

$750

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

lun. 2/2

12:55 am-8:56 pm

1 stop26h 01m

Greenville

mar. 2/10

6:00 am-8:55 am

1 stop20h 55m

$750

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

jue. 2/19

6:00 am-7:24 pm

2 stops19h 24m

Greenville

sáb. 3/7

5:00 pm-8:05 am

2 stops33h 05m

$752

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

vie. 2/20

6:00 am-6:12 pm

2 stops18h 12m

Charleston

mar. 2/24

10:20 am-9:15 am

2 stops16h 55m

$752

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

vie. 2/20

11:15 am-6:12 pm

1 stop12h 57m

Charleston

mar. 2/24

11:15 am-9:15 am

1 stop16h 00m

$773

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

lun. 1/26

6:00 am-9:16 pm

2 stops21h 16m

Charlotte Douglas

mié. 2/4

2:20 pm-9:15 am

1 stop12h 55m

$777

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

mar. 1/27

6:00 am-9:16 pm

2 stops21h 16m

Charlotte Douglas

jue. 2/5

2:20 pm-9:15 am

1 stop12h 55m

$777

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

mié. 1/21

8:30 am-9:16 pm

2 stops18h 46m

Charlotte Douglas

lun. 2/9

2:20 pm-9:15 am

1 stop12h 55m

$777

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

vie. 2/20

8:35 am-1:52 pm

2 stops35h 17m

Charleston

jue. 3/19

4:50 pm-8:05 am

2 stops58h 15m

$781

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 53 results
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Best time to book a flight from Madrid to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to South Carolina

What is the cheapest month to book a flight from Madrid to South Carolina?

Currently, January is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $579). Flying from Madrid to South Carolina in July is currently the most expensive (average of $923). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Madrid to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madrid to South Carolina?

    Madrid Barajas (MAD) is the airport you will fly out of if you book a flight from Madrid to South Carolina. It is only a 8.5 mi journey to Barajas (MAD) from Madrid’s city center.

  • How long is the flight from Madrid to South Carolina?

    A quick flight from Madrid to South Carolina can take about 13h 44m. American Airlines provides one of the quickest options available for as low as $750. Madrid and South Carolina are separated by a distance of 4169 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madrid to South Carolina?

    When deciding which route to take from Madrid to South Carolina consider Madrid Barajas - Charlotte Douglas, Madrid Barajas - Charleston or Madrid Barajas - Myrtle Beach Intl as they are the most popular.

  • Can I find deals for flights from Madrid to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madrid to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to South Carolina.

  • Can I find deals for business class flights from Madrid to South Carolina?

    Yes. Cheapflights offers flight deals from Madrid to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $579). Flying from Madrid to South Carolina in July is currently the most expensive (average of $923). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Madrid to South Carolina

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