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$401+ Cheap flights from Madrid, Spain (MAD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — CHS
Jun 11 — Jun 181
Thu 6/11
Thu 6/18
1 adult, Economy
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Cheap flight deals from Madrid to South Carolina

Cheapest flights from Madrid to South Carolina
Explore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.

This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:50 am
MAD
-
CLT
1 stop28h 45m
United Airlines
Sun 6/76:40 pm
CLT
-
MAD
2 stops19h 10m
United Airlines
Deal found 5/12$740
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:05 pm
MAD
-
CHS
1 stop28h 05m
JetBlue
Sat 9/124:00 pm
CHS
-
MAD
1 stop13h 30m
JetBlue
Deal found 5/9$740
This lol.travel deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:05 pm
MAD
-
CHS
1 stop33h 45m
JetBlue
Wed 7/16:45 pm
CHS
-
MAD
1 stop10h 45m
JetBlue
Deal found 5/10$831
This Lufthansa deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:25 am
MAD
-
CLT
2 stops16h 37m
Lufthansa
Tue 6/92:53 pm
CLT
-
MAD
1 stop11h 12m
Lufthansa
Deal found 5/9$849
This Lufthansa deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:15 am
MAD
-
CLT
1 stop18h 44m
Lufthansa
Sun 10/410:30 am
CLT
-
MAD
1 stop15h 35m
Lufthansa
Deal found 5/7$864
This FlightHub deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:35 pm
MAD
-
CLT
2 stops33h 17m
Scandinavian Airlines
Sun 6/76:00 am
CLT
-
MAD
2 stops29h 40m
Scandinavian Airlines
Deal found 5/11$865
This Rumbo deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:35 pm
MAD
-
CLT
2 stops32h 24m
Scandinavian Airlines
Mon 6/14:46 pm
CLT
-
MAD
2 stops20h 09m
Scandinavian Airlines
Deal found 5/12$866
This Rumbo deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:30 pm
MAD
-
CLT
2 stops33h 29m
Scandinavian Airlines
Sat 6/65:30 pm
CLT
-
MAD
2 stops18h 15m
Scandinavian Airlines
Deal found 5/10$871
This Flighttix deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:05 pm
MAD
-
CHS
1 stop26h 54m
JetBlue
Thu 6/44:01 pm
CHS
-
MAD
1 stop13h 29m
JetBlue
Deal found 5/9$879
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:05 pm
MAD
-
CHS
1 stop28h 05m
JetBlue
Fri 7/246:42 pm
CHS
-
MAD
1 stop10h 48m
JetBlue
Deal found 5/9$889
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am
MAD
-
GSP
2 stops18h 49m
Delta
Wed 2/245:05 pm
GSP
-
MAD
2 stops18h 35m
Delta
Deal found 5/11$892
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:00 am
MAD
-
GSP
2 stops17h 21m
Delta
Tue 2/233:42 pm
GSP
-
MAD
2 stops17h 38m
Delta
Deal found 5/11$897

Find flight deals from Madrid to South Carolina

Keep the following information in mind while searching for Madrid to South Carolina flight deals. Data was last updated May 12, 2026.

Round-trip from

$740
(United Airlines)

One-way from

$401
(Kiwi.com)
From Madrid Barajas to South Carolina
Search Deals
One-way flight from Madrid Barajas to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Madrid to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Tue 6/2

8:25 am-7:02 pm

2 stops16h 37m

Charlotte Douglas

Tue 6/9

2:53 pm-8:05 am

1 stop11h 12m

$849

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Mon 11/2

10:00 am-9:21 pm

2 stops17h 21m

Greenville

Tue 2/23

3:42 pm-3:20 pm

2 stops17h 38m

$897

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Fri 5/22

6:00 am-11:52 pm

2 stops23h 52m

Savannah/Hilton Head

Tue 8/4

3:24 pm-9:00 am

1 stop11h 36m

$913

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Tue 11/3

6:00 am-9:58 pm

2 stops21h 58m

Greenville

Thu 2/25

3:42 pm-11:30 am

2 stops13h 48m

$915

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Mon 11/2

1:05 pm-11:37 pm

2 stops16h 32m

Greenville

Thu 2/25

7:55 pm-5:40 pm

2 stops15h 45m

$916

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Sat 6/6

10:50 am-11:56 pm

1 stop19h 06m

Charleston

Fri 6/12

3:34 pm-9:00 am

1 stop11h 26m

$925

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 5/28

10:25 am-10:02 pm

2 stops17h 37m

Charleston

Mon 6/1

6:38 pm-4:25 pm

2 stops15h 47m

$926

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Fri 5/22

12:45 pm-9:39 pm

1 stop14h 54m

Savannah/Hilton Head

Tue 8/4

5:52 pm-9:55 am

1 stop34h 03m

$928

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 10/15

11:15 am-11:59 pm

2 stops18h 44m

Charleston

Mon 10/19

2:46 pm-8:05 am

1 stop11h 19m

$928

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Sat 5/23

11:15 am-11:56 pm

2 stops18h 41m

Charleston

Sat 6/6

6:00 am-9:00 am

1 stop21h 00m

$928

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/12

Showing 1-10 of 54 resultsSorted by cheapest first
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Best time to book a flight from Madrid to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to South Carolina

What is the cheapest month to book a flight from Madrid to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $648). Flying from Madrid to South Carolina in July is currently the most expensive (average of $920). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Madrid to South Carolina?

Related info for your journey

Find useful and relevant information for your journey from Madrid to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madrid to South Carolina?

    Madrid Barajas (MAD) is the airport you will fly out of if you book a flight from Madrid to South Carolina. It is only a 8.5 mi journey to Barajas (MAD) from Madrid’s city center.

  • How long is the flight from Madrid to South Carolina?

    A quick flight from Madrid to South Carolina can take about 16h 37m. Lufthansa provides one of the quickest options available for as low as $849. Madrid and South Carolina are separated by a distance of 4096 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madrid to South Carolina?

    When deciding which route to take from Madrid to South Carolina consider Madrid Barajas - Charlotte Douglas, Madrid Barajas - Charleston or Madrid Barajas - Greenville as they are the most popular.

  • Can I find deals for flights from Madrid to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madrid to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to South Carolina.

  • Can I find deals for business class flights from Madrid to South Carolina?

    Yes. Cheapflights offers flight deals from Madrid to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $648). Flying from Madrid to South Carolina in July is currently the most expensive (average of $920). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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