HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$351+ Cheap flights from Madrid, Spain (MAD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — CHS
May 3 — May 101
Sun 5/3
Sun 5/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Madrid to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Madrid to South Carolina

Cheapest flights from Madrid to South Carolina
Explore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2026.

This Trip.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:40 am
MAD
-
CLT
2 stops22h 13m
Multiple Airlines
Mon 4/2710:16 am
CLT
-
MAD
2 stops26h 54m
Multiple Airlines
Deal found 3/30$614
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:40 pm
MAD
-
CLT
3 stops34h 07m
Multiple Airlines
Sun 4/2610:16 am
CLT
-
MAD
2 stops25h 04m
Multiple Airlines
Deal found 3/30$630
This Trip.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:55 am
MAD
-
CLT
2 stops22h 06m
Multiple Airlines
Mon 4/2710:16 am
CLT
-
MAD
2 stops24h 54m
Multiple Airlines
Deal found 3/31$670
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:40 pm
MAD
-
CLT
3 stops34h 07m
Multiple Airlines
Wed 4/2910:16 am
CLT
-
MAD
2 stops29h 09m
Multiple Airlines
Deal found 3/31$673
This Trip.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1011:05 am
MAD
-
CHS
2 stops32h 39m
Multiple Airlines
Sat 5/162:39 pm
CHS
-
MAD
2 stops22h 31m
Multiple Airlines
Deal found 4/2$711
This JetBlue deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:30 pm
MAD
-
CHS
1 stop25h 34m
JetBlue
Thu 5/146:00 am
CHS
-
MAD
1 stop23h 30m
JetBlue
Deal found 4/3$724
This Expedia deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:30 pm
MAD
-
CHS
1 stop27h 55m
Multiple Airlines
Mon 11/22:30 pm
CHS
-
MAD
1 stop11h 30m
Multiple Airlines
Deal found 4/3$797
This Flighttix deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:30 pm
MAD
-
CHS
1 stop32h 07m
JetBlue
Wed 4/299:44 am
CHS
-
MAD
1 stop19h 46m
JetBlue
Deal found 3/30$802
This Flighttix deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:30 pm
MAD
-
CHS
1 stop13h 53m
JetBlue
Sat 5/164:36 pm
CHS
-
MAD
1 stop12h 54m
JetBlue
Deal found 4/2$807
This Justfly.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:30 pm
MAD
-
SAV
1 stop15h 48m
JetBlue
Sat 5/98:29 pm
SAV
-
MAD
1 stop33h 01m
JetBlue
Deal found 3/29$816
This Priceline deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:05 pm
MAD
-
CHS
1 stop26h 54m
JetBlue
Mon 6/88:51 pm
CHS
-
MAD
1 stop32h 39m
JetBlue
Deal found 4/3$818
This Expedia deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:05 pm
MAD
-
CHS
1 stop26h 54m
JetBlue
Mon 6/152:02 pm
CHS
-
MAD
1 stop15h 28m
JetBlue
Deal found 4/3$829

Find flight deals from Madrid to South Carolina

Keep the following information in mind while searching for Madrid to South Carolina flight deals. Data was last updated April 3, 2026.

Round-trip from

$614
(Trip.com)

One-way from

$351
(Kiwi.com)
From Madrid Barajas to South Carolina
Search Deals
One-way flight from Madrid Barajas to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Madrid to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Fri 4/17

6:00 am-6:54 pm

2 stops18h 54m

Savannah/Hilton Head

Mon 4/27

4:59 pm-4:45 pm

2 stops17h 46m

$879

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Fri 4/17

12:45 pm-9:27 am

1 stop26h 42m

Savannah/Hilton Head

Mon 4/27

3:18 pm-12:15 pm

1 stop14h 57m

$888

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Wed 4/15

1:00 pm-10:40 pm

1 stop15h 40m

Greenville

Sun 4/19

12:14 pm-9:05 am

1 stop14h 51m

$891

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 4/23

8:10 pm-11:08 am

2 stops44h 58m

Charleston

Wed 4/29

12:05 pm-9:55 am

1 stop15h 50m

$894

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Wed 4/15

8:25 am-9:37 am

2 stops31h 12m

Savannah/Hilton Head

Sun 4/19

5:40 am-8:05 am

1 stop20h 25m

$894

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Sat 5/2

5:55 am-6:25 pm

2 stops18h 30m

Savannah/Hilton Head

Sun 5/10

5:45 am-8:05 am

1 stop20h 20m

$896

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Thu 4/30

2:35 pm-9:48 pm

1 stop13h 13m

Savannah/Hilton Head

Sun 5/10

7:15 am-9:55 am

1 stop20h 40m

$899

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Thu 9/24

7:45 pm-10:39 pm

2 stops32h 54m

Savannah/Hilton Head

Mon 9/28

5:35 pm-6:55 pm

2 stops19h 20m

$900

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Fri 5/1

10:25 am-11:59 pm

2 stops19h 34m

Savannah/Hilton Head

Sun 5/10

7:59 pm-4:45 pm

2 stops14h 46m

$902

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Tue 9/1

6:00 am-4:54 pm

2 stops16h 54m

Charleston

Mon 9/7

5:25 pm-3:35 pm

2 stops16h 10m

$903

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/2

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Madrid to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to South Carolina

What is the cheapest month to book a flight from Madrid to South Carolina?

Currently, March is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $679). Flying from Madrid to South Carolina in July is currently the most expensive (average of $923). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Madrid to South Carolina?

Related info for your journey

Find useful and relevant information for your journey from Madrid to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madrid to South Carolina?

    Madrid Barajas (MAD) is the airport you will fly out of if you book a flight from Madrid to South Carolina. It is only a 8.5 mi journey to Barajas (MAD) from Madrid’s city center.

  • How long is the flight from Madrid to South Carolina?

    A quick flight from Madrid to South Carolina can take about 18h 54m. JetBlue provides one of the quickest options available for as low as $879. Madrid and South Carolina are separated by a distance of 4219 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madrid to South Carolina?

    When deciding which route to take from Madrid to South Carolina consider Madrid Barajas - Charlotte Douglas, Madrid Barajas - Charleston or Madrid Barajas - Myrtle Beach Intl as they are the most popular.

  • Can I find deals for flights from Madrid to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madrid to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to South Carolina.

  • Can I find deals for business class flights from Madrid to South Carolina?

    Yes. Cheapflights offers flight deals from Madrid to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to South Carolina?

    Currently, March is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $679). Flying from Madrid to South Carolina in July is currently the most expensive (average of $923). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.