$403+ Cheap flights from Madrid, Spain (MAD) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — CHS
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Madrid to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Madrid to South CarolinaExplore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This lol.travel deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:00 pm -
Nonstop9h 25m
Mon 11/167:08 am -
1 stop19h 42m
Deal found 9/7![Finnair logo]()
$725
This lol.travel deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:00 pm -
Nonstop9h 25m
Mon 11/169:05 am -
1 stop17h 45m
Deal found 9/6![Finnair logo]()
$741
This Finnair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1712:40 pm -
Nonstop9h 30m
Tue 1/128:15 pm -
1 stop12h 00m
Deal found 9/5![Multiple Airlines logo]()
$752
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:05 am -
2 stops20h 05m
Sat 1/164:30 pm -
2 stops19h 15m
Deal found 9/5![Delta logo]()
$755
This Expedia deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:00 pm -
Nonstop9h 25m
Wed 11/186:25 pm -
1 stop13h 10m
Deal found 9/6![Iberia logo]()
$756
This Expedia deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/171:15 pm -
1 stop12h 19m
Tue 1/128:15 pm -
1 stop12h 00m
Deal found 9/5![British Airways logo]()
$757
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1712:40 pm -
Nonstop9h 30m
Tue 1/123:45 pm -
Nonstop8h 00m
Deal found 9/5![American Airlines logo]()
$759
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:20 am -
2 stops16h 52m
Tue 1/125:24 pm -
2 stops18h 21m
Deal found 9/5![Delta logo]()
$760
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:05 am -
2 stops17h 14m
Fri 1/155:35 pm -
2 stops18h 10m
Deal found 9/6![Delta logo]()
$806
This Air France deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/159:20 am -
1 stop18h 03m
Fri 1/157:25 am -
1 stop17h 55m
Deal found 9/6![Multiple Airlines logo]()
$823
This Flighttix deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:45 pm -
2 stops17h 14m
Sun 9/276:30 am -
2 stops18h 20m
Deal found 9/7![Air Canada logo]()
$919
This Flighttix deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:45 pm -
2 stops26h 28m
Sun 9/273:00 pm -
1 stop11h 05m
Deal found 9/7![Multiple Airlines logo]()
$920
Best flights from Madrid to South CarolinaDiscover carefully curated flight deals from Madrid to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Madrid to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This British Airways deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1812:40 pm -
Nonstop9h 30m
Mon 2/223:45 pm -
Nonstop8h 00m
Deal found 9/8![British Airways logo]()
$729
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:05 am -
2 stops18h 40m
Sun 11/299:47 am -
1 stop17h 58m
Deal found 9/8![Delta logo]()
$788
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:30 pm -
2 stops51h 56m
Mon 10/59:15 am -
1 stop17h 35m
Deal found 9/8![United Airlines logo]()
$828
This Finnair deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:40 pm -
Nonstop9h 15m
Mon 11/22:54 pm -
1 stop11h 56m
Deal found 9/4![Multiple Airlines logo]()
$890
This Virgin Atlantic deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:50 am -
1 stop14h 23m
Wed 10/282:15 pm -
1 stop14h 30m
Deal found 9/5![Virgin Atlantic logo]()
$935
This British Airways deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:00 pm -
Nonstop9h 25m
Mon 11/1611:00 am -
1 stop12h 50m
Deal found 9/7![British Airways logo]()
$787
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:50 am -
2 stops17h 04m
Thu 11/264:59 pm -
1 stop10h 46m
Deal found 9/9![Delta logo]()
$788
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1811:15 am -
1 stop29h 06m
Mon 2/222:30 pm -
1 stop12h 45m
Deal found 9/6![United Airlines logo]()
$877
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/16:05 am -
2 stops21h 41m
Sat 3/135:25 pm -
2 stops15h 55m
Deal found 9/4![Delta logo]()
$806
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2111:15 am -
1 stop18h 10m
Mon 1/258:30 am -
2 stops18h 45m
Deal found 9/6![United Airlines logo]()
$877
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:05 am -
2 stops17h 14m
Fri 1/155:35 pm -
2 stops18h 10m
Deal found 9/6![Delta logo]()
$806
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:15 am -
1 stop17h 45m
Mon 11/162:51 pm -
1 stop10h 54m
Deal found 9/6![United Airlines logo]()
$935
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:50 am -
1 stop14h 23m
Wed 10/2810:52 am -
2 stops19h 38m
Deal found 9/5![Delta logo]()
$932
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:15 am -
1 stop29h 06m
Mon 11/1611:27 am -
1 stop15h 48m
Deal found 9/6![United Airlines logo]()
$935
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:35 pm -
1 stop27h 45m
Tue 9/296:00 am -
1 stop24h 15m
Deal found 9/9![Delta logo]()
$936
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:05 am -
2 stops21h 10m
Sun 10/1111:00 am -
2 stops15h 05m
Deal found 9/7![United Airlines logo]()
$961
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:55 am -
2 stops21h 20m
Tue 10/273:05 pm -
1 stop11h 40m
Deal found 9/5![United Airlines logo]()
$962
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:20 am -
2 stops21h 39m
Sat 10/179:54 am -
1 stop17h 06m
Deal found 9/8![United Airlines logo]()
$962
Last-minute flights from Madrid to South CarolinaDiscover last-minute flight deals from Madrid to South Carolina. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Madrid to South Carolina. Data last updated September 9, 2026 and is based on user searches.
This lol.travel deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:00 pm -
Nonstop9h 15m
Wed 9/3011:35 am -
1 stop12h 00m
Deal found 9/9![Finnair logo]()
$773
This Finnair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:00 pm -
Nonstop9h 15m
Wed 9/304:15 pm -
1 stop12h 00m
Deal found 9/8![Multiple Airlines logo]()
$787
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:25 am -
1 stop13h 10m
Wed 9/3011:35 am -
1 stop12h 00m
Deal found 9/9![Iberia logo]()
$792
This Flighttix deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:45 pm -
2 stops17h 14m
Sun 9/276:30 am -
2 stops18h 20m
Deal found 9/7![Air Canada logo]()
$919
This Flighttix deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:45 pm -
2 stops26h 28m
Sun 9/273:00 pm -
1 stop11h 05m
Deal found 9/7![Multiple Airlines logo]()
$920
This lol.travel deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:00 pm -
Nonstop9h 15m
Mon 10/56:28 pm -
1 stop13h 02m
Deal found 9/8![Finnair logo]()
$790
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:25 am -
2 stops31h 19m
Fri 10/3011:27 am -
2 stops39h 18m
Deal found 9/8![United Airlines logo]()
$921
This British Airways deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:00 pm -
Nonstop9h 15m
Mon 11/25:05 pm -
2 stops19h 30m
Deal found 9/9![British Airways logo]()
$798
This British Airways deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:30 pm -
1 stop26h 18m
Tue 11/33:34 pm -
2 stops14h 41m
Deal found 9/9![British Airways logo]()
$786
This British Airways deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:30 pm -
1 stop23h 55m
Sun 11/810:49 pm -
1 stop28h 36m
Deal found 9/9![British Airways logo]()
$793
This British Airways deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:00 pm -
Nonstop9h 15m
Thu 11/58:26 pm -
2 stops18h 04m
Deal found 9/9![British Airways logo]()
$780
This British Airways deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:00 pm -
Nonstop9h 15m
Thu 11/54:00 pm -
Nonstop7h 45m
Deal found 9/9![British Airways logo]()
$788
One-way flights from Madrid to South CarolinaSearch for one-way flight options from Madrid to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Madrid to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/71:10 pm -
2 stops48h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:45 am -
3 stops45h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$424
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/91:55 pm -
3 stops48h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$446
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:00 pm -
2 stops46h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$452
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:45 pm -
2 stops42h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$473
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:40 pm -
3 stops40h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$543
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:15 pm -
2 stops43h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$544
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:45 am -
3 stops55h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$549
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:25 pm -
2 stops50h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$564
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:05 pm -
2 stops26h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Delta logo]()
$588
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:30 pm -
3 stops57h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$596
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:45 pm -
3 stops24h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$600
Find flight deals from Madrid to South Carolina
Keep the following information in mind while searching for Madrid to South Carolina flight deals. Data was last updated September 9, 2026.
Round-trip from | $658 (eDestinos) |
|---|---|
One-way from | $403 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Madrid to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Madrid to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MadridCharleston
MAD Madrid Barajas - CHS Charleston
MADCHS
Madrid Barajas
Wed 9/30
10:40 pm-8:48 am
3 stops40h 08m
Charleston
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$543
MadridCharleston
MAD Madrid Barajas - CHS Charleston
MADCHS
Madrid Barajas
Mon 10/26
8:10 pm-8:38 am
3 stops41h 28m
Charleston
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$565
MadridCharleston
MAD Madrid Barajas - CHS Charleston
MADCHS
Madrid Barajas
Sat 9/19
3:10 pm-8:48 am
3 stops47h 38m
Charleston
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$569
MadridCharlotte
MAD Madrid Barajas - CLT Charlotte Douglas
MADCLT
Madrid Barajas
Thu 1/7
6:05 am-10:16 pm
2 stops22h 11m
Charlotte Douglas
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$575
MadridCharlotte
MAD Madrid Barajas - CLT Charlotte Douglas
MADCLT
Madrid Barajas
Tue 3/2
6:05 am-9:50 pm
2 stops21h 45m
Charlotte Douglas
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$575
MadridCharlotte
MAD Madrid Barajas - CLT Charlotte Douglas
MADCLT
Madrid Barajas
Mon 3/8
12:20 pm-11:53 pm
1 stop17h 33m
Charlotte Douglas
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$580
MadridCharleston
MAD Madrid Barajas - CHS Charleston
MADCHS
Madrid Barajas
Wed 12/9
2:55 pm-10:36 pm
3 stops37h 41m
Charleston
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$582
MadridCharleston
MAD Madrid Barajas - CHS Charleston
MADCHS
Madrid Barajas
Tue 10/27
1:05 pm-10:10 am
2 stops26h 05m
Charleston
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$588
MadridCharleston
MAD Madrid Barajas - CHS Charleston
MADCHS
Madrid Barajas
Tue 10/27
4:30 pm-10:32 am
1 stop23h 02m
Charleston
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$589
MadridGreenville
MAD Madrid Barajas - GSP Greenville
MADGSP
Madrid Barajas
Sat 10/3
3:30 pm-6:40 pm
3 stops57h 10m
Greenville
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
$596
Showing 1-10 of 45 resultsSorted by cheapest first
Best time to book a flight from Madrid to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madrid with our price prediction graph.
MAD-CLT
MAD-CHS
MAD-MYR
MAD-SAV
MAD-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to South Carolina
MAD-USSC
MAD-CLT
MAD-CHS
MAD-MYR
MAD-SAV
What is the cheapest month to book a flight from Madrid to South Carolina?
Currently, March is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $701). Flying from Madrid to South Carolina in August is currently the most expensive (average of $1,352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Madrid to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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