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$404+ Cheap flights from Madrid, Spain (MAD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — CHS
Jul 2 — Jul 91
Thu 7/2
Thu 7/9
1 adult, Economy
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Cheap flight deals from Madrid to South Carolina

Cheapest flights from Madrid to South Carolina
Explore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 2, 2026.

This JetBlue deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/172:05 pm
MAD
-
SAV
1 stop25h 44m
JetBlue
Sun 6/219:18 am
SAV
-
MAD
1 stop20h 12m
JetBlue
Deal found 6/1$666
This eDestinos deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/111:00 am
MAD
-
CLT
Nonstop9h 30m
Iberia
Mon 2/16:25 pm
CLT
-
MAD
1 stop13h 50m
Iberia
Deal found 5/29$829
This JetBlue deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/132:05 pm
MAD
-
SAV
1 stop25h 44m
JetBlue
Wed 6/179:18 am
SAV
-
MAD
1 stop20h 12m
JetBlue
Deal found 5/29$833
This eDestinos deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:00 am
MAD
-
CLT
1 stop30h 09m
Virgin Atlantic
Mon 2/111:45 am
CLT
-
MAD
2 stops14h 15m
Virgin Atlantic
Deal found 5/29$840
This Rumbo deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:40 am
MAD
-
CHS
2 stops19h 20m
TAP AIR PORTUGAL
Sat 12/1210:51 am
CHS
-
MAD
2 stops18h 29m
TAP AIR PORTUGAL
Deal found 5/29$849
This lol.travel deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/132:05 pm
MAD
-
SAV
1 stop25h 59m
JetBlue
Mon 7/209:38 am
SAV
-
MAD
1 stop19h 52m
JetBlue
Deal found 5/29$876
This TAP AIR PORTUGAL deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TAP AIR PORTUGAL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:05 am
MAD
-
CHS
2 stops29h 05m
TAP AIR PORTUGAL
Sat 9/124:00 pm
CHS
-
MAD
2 stops19h 00m
TAP AIR PORTUGAL
Deal found 6/2$885
This lol.travel deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/122:05 pm
MAD
-
CHS
1 stop27h 26m
JetBlue
Tue 6/166:45 pm
CHS
-
MAD
1 stop10h 45m
JetBlue
Deal found 5/29$892
This Mytrip deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:30 pm
MAD
-
CLT
3 stops28h 10m
Multiple Airlines
Mon 9/219:20 am
CLT
-
MAD
3 stops31h 45m
Multiple Airlines
Deal found 5/29$902
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am
MAD
-
CLT
2 stops18h 16m
Delta
Mon 2/11:15 pm
CLT
-
MAD
2 stops16h 15m
Delta
Deal found 5/29$904
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am
MAD
-
CHS
2 stops23h 59m
United Airlines
Mon 9/2111:10 am
CHS
-
MAD
2 stops14h 55m
United Airlines
Deal found 5/28$904
This KLM deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:05 am
MAD
-
CLT
2 stops17h 11m
Multiple Airlines
Mon 2/13:30 pm
CLT
-
MAD
2 stops14h 00m
Multiple Airlines
Deal found 6/1$905

Find flight deals from Madrid to South Carolina

Keep the following information in mind while searching for Madrid to South Carolina flight deals. Data was last updated June 2, 2026.

Round-trip from

$666
(JetBlue)

One-way from

$404
(Kiwi.com)
From Madrid Barajas to South Carolina
Search Deals
One-way flight from Madrid Barajas to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 2, 2026.
Use the filters below to find and compare flights from Madrid to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Sat 9/5

11:05 am-10:10 am

2 stops29h 05m

Charleston

Sat 9/12

4:00 pm-5:00 pm

2 stops19h 00m

$885

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Fri 9/18

8:25 am-11:59 pm

2 stops21h 34m

Charleston

Mon 9/21

7:00 am-9:00 am

1 stop20h 00m

$904

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Sat 9/5

5:55 am-9:34 pm

2 stops21h 39m

Charleston

Sat 9/12

10:19 am-8:05 am

1 stop15h 46m

$905

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Sun 11/1

7:05 am-6:16 pm

2 stops17h 11m

Charlotte Douglas

Mon 2/1

6:59 pm-8:00 am

1 stop31h 01m

$909

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Sun 9/6

6:00 am-8:34 pm

2 stops20h 34m

Charlotte Douglas

Mon 9/21

10:00 am-9:10 am

2 stops17h 10m

$916

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Fri 10/23

10:25 am-10:06 pm

2 stops17h 41m

Charlotte Douglas

Mon 11/2

6:59 pm-4:05 pm

2 stops15h 06m

$922

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

Sat 6/13

11:15 am-7:48 pm

1 stop14h 33m

Savannah/Hilton Head

Wed 6/17

12:10 pm-11:50 am

2 stops17h 40m

$926

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Sun 9/13

9:50 am-8:23 pm

1 stop16h 33m

Charlotte Douglas

Sat 10/10

4:30 pm-12:15 pm

1 stop13h 45m

$928

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Fri 6/12

6:00 am-9:48 pm

2 stops21h 48m

Greenville

Fri 7/10

7:44 pm-12:15 pm

1 stop10h 31m

$961

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Fri 8/21

11:05 am-10:10 am

2 stops29h 05m

Charleston

Sun 9/20

12:45 pm-12:40 pm

2 stops17h 55m

$1,022

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/29

Showing 1-10 of 59 resultsSorted by cheapest first
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Best time to book a flight from Madrid to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to South Carolina

What is the cheapest month to book a flight from Madrid to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $648). Flying from Madrid to South Carolina in August is currently the most expensive (average of $951). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Madrid to South Carolina?

Related info for your journey

Find useful and relevant information for your journey from Madrid to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madrid to South Carolina?

    Madrid Barajas (MAD) is the airport you will fly out of if you book a flight from Madrid to South Carolina. It is only a 8.5 mi journey to Barajas (MAD) from Madrid’s city center.

  • How long is the flight from Madrid to South Carolina?

    A quick flight from Madrid to South Carolina can take about 17h 11m. TAP AIR PORTUGAL provides one of the quickest options available for as low as $909. Madrid and South Carolina are separated by a distance of 4096 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madrid to South Carolina?

    When deciding which route to take from Madrid to South Carolina consider Madrid Barajas - Charlotte Douglas, Madrid Barajas - Charleston or Madrid Barajas - Greenville as they are the most popular.

  • Can I find deals for flights from Madrid to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madrid to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to South Carolina.

  • Can I find deals for business class flights from Madrid to South Carolina?

    Yes. Cheapflights offers flight deals from Madrid to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $648). Flying from Madrid to South Carolina in August is currently the most expensive (average of $951). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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