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South Carolina

$384+ Cheap flights from Madrid, Spain (MAD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — CHS
may. 18 — may. 251
lun. 5/18
lun. 5/25
1 adult, Economy
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Cheap flight deals from Madrid to South Carolina

Cheapest flights from Madrid to South Carolina
Explore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 18, 2026.

This Trip.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/115:55 am
MAD
-
CLT
2 stops22h 06m
Multiple Airlines
lun. 5/257:12 am
CLT
-
MAD
2 stops27h 58m
Multiple Airlines
Deal found 4/15$709
This Trip.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/121:40 pm
MAD
-
MYR
3 stops31h 08m
Multiple Airlines
mar. 5/1910:24 am
MYR
-
MAD
2 stops31h 56m
Multiple Airlines
Deal found 4/14$728
This Mytrip deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/2911:05 am
MAD
-
CLT
3 stops33h 31m
Multiple Airlines
dom. 5/310:16 am
CLT
-
MAD
2 stops23h 09m
Multiple Airlines
Deal found 4/13$759
This Trip.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/283:35 pm
MAD
-
CLT
1 stop31h 36m
Multiple Airlines
mar. 6/97:12 am
CLT
-
MAD
1 stop22h 08m
Multiple Airlines
Deal found 4/16$767
This Trip.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/206:05 pm
MAD
-
CLT
2 stops33h 56m
Multiple Airlines
lun. 5/47:12 am
CLT
-
MAD
2 stops21h 33m
Multiple Airlines
Deal found 4/18$796
This lol.travel deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/41:30 pm
MAD
-
CHS
1 stop25h 14m
JetBlue
vie. 5/84:36 pm
CHS
-
MAD
1 stop12h 54m
JetBlue
Deal found 4/14$811
This Flighttix deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/101:30 pm
MAD
-
CHS
1 stop25h 14m
JetBlue
sáb. 5/166:00 am
CHS
-
MAD
1 stop23h 30m
JetBlue
Deal found 4/17$830
This Trip.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/275:55 am
MAD
-
CLT
2 stops22h 06m
Multiple Airlines
mar. 6/97:12 am
CLT
-
MAD
2 stops41h 38m
Multiple Airlines
Deal found 4/14$838
This Priceline deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/292:05 pm
MAD
-
CHS
1 stop26h 54m
JetBlue
vie. 6/58:52 pm
CHS
-
MAD
1 stop32h 38m
JetBlue
Deal found 4/14$838
This eDestinos deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/79:50 am
MAD
-
GSP
1 stop19h 53m
Virgin Atlantic
lun. 5/1111:43 am
GSP
-
MAD
2 stops16h 12m
Virgin Atlantic
Deal found 4/17$840
This Rumbo deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/206:30 pm
MAD
-
CLT
2 stops33h 29m
Scandinavian Airlines
jue. 5/284:46 pm
CLT
-
MAD
2 stops18h 54m
Scandinavian Airlines
Deal found 4/17$848
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/303:25 pm
MAD
-
CLT
1 stop28h 18m
Multiple Airlines
lun. 5/45:30 pm
CLT
-
MAD
2 stops35h 15m
Multiple Airlines
Deal found 4/14$852

Find flight deals from Madrid to South Carolina

Keep the following information in mind while searching for Madrid to South Carolina flight deals. Data was last updated abril 18, 2026.

Round-trip from

$709
(Trip.com)

One-way from

$384
(Kiwi.com)
From Madrid Barajas to South Carolina
Search Deals
One-way flight from Madrid Barajas to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 18, 2026.
Use the filters below to find and compare flights from Madrid to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridMyrtle Beach

MAD - MYR

MADMYR

Madrid Barajas

mar. 5/12

1:40 pm-9:46 am

2 stops26h 06m

Myrtle Beach Intl

mar. 5/19

10:24 am-3:20 pm

2 stops22h 56m

$754

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

lun. 5/4

1:30 pm-11:04 am

1 stop27h 34m

Savannah/Hilton Head

vie. 5/8

8:29 pm-11:30 am

1 stop33h 01m

$878

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

mar. 6/2

10:50 am-11:52 pm

1 stop19h 02m

Savannah/Hilton Head

mar. 6/9

3:24 pm-9:00 am

1 stop11h 36m

$906

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

mar. 9/15

5:55 am-10:13 pm

2 stops22h 18m

Charleston

dom. 9/20

7:52 pm-8:05 am

1 stop30h 13m

$910

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

mié. 4/29

5:55 am-6:15 pm

2 stops18h 20m

Savannah/Hilton Head

dom. 5/3

7:15 pm-8:05 am

1 stop30h 50m

$910

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

jue. 6/18

8:20 am-9:17 pm

2 stops18h 57m

Greenville

lun. 8/31

10:25 am-8:05 am

1 stop15h 40m

$916

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

sáb. 5/2

5:55 am-6:25 pm

2 stops18h 30m

Savannah/Hilton Head

mié. 5/6

10:18 am-9:00 am

1 stop16h 42m

$916

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

jue. 6/18

6:00 am-7:00 pm

2 stops19h 00m

Greenville

lun. 8/31

6:45 am-9:55 am

2 stops21h 10m

$925

MadridSavannah

MAD - SAV

MADSAV

Madrid Barajas

jue. 5/7

11:15 am-7:26 pm

1 stop14h 11m

Savannah/Hilton Head

lun. 5/11

12:19 pm-9:00 am

2 stops14h 41m

$925

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

jue. 9/24

11:15 am-7:08 pm

1 stop13h 53m

Charleston

lun. 9/28

2:46 pm-8:05 am

1 stop11h 19m

$930

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Madrid to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to South Carolina

What is the cheapest month to book a flight from Madrid to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $648). Flying from Madrid to South Carolina in July is currently the most expensive (average of $920). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Madrid to South Carolina?

Related info for your journey

Find useful and relevant information for your journey from Madrid to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madrid to South Carolina?

    Madrid Barajas (MAD) is the airport you will fly out of if you book a flight from Madrid to South Carolina. It is only a 8.5 mi journey to Barajas (MAD) from Madrid’s city center.

  • How long is the flight from Madrid to South Carolina?

    A quick flight from Madrid to South Carolina can take about 19h 02m. JetBlue provides one of the quickest options available for as low as $906. Madrid and South Carolina are separated by a distance of 4219 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madrid to South Carolina?

    When deciding which route to take from Madrid to South Carolina consider Madrid Barajas - Charlotte Douglas, Madrid Barajas - Savannah/Hilton Head or Madrid Barajas - Charleston as they are the most popular.

  • Can I find deals for flights from Madrid to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madrid to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to South Carolina.

  • Can I find deals for business class flights from Madrid to South Carolina?

    Yes. Cheapflights offers flight deals from Madrid to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $648). Flying from Madrid to South Carolina in July is currently the most expensive (average of $920). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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