HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$379+ Cheap flights from Madrid, Spain (MAD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — CHS
Aug 19 — Aug 261
Wed 8/19
Wed 8/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Madrid to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Madrid to South Carolina

Cheapest flights from Madrid to South Carolina
Explore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 20, 2026.

This Ovago deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/92:05 pm
MAD
-
SAV
1 stop25h 59m
JetBlue
Sat 8/158:51 pm
SAV
-
MAD
1 stop32h 39m
JetBlue
Deal found 7/17$652
This lol.travel deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:05 pm
MAD
-
CHS
1 stop33h 41m
JetBlue
Sat 9/123:04 pm
CHS
-
MAD
1 stop14h 26m
JetBlue
Deal found 7/19$680
This Ovago deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/92:05 pm
MAD
-
CHS
1 stop34h 15m
JetBlue
Sat 8/156:40 pm
CHS
-
MAD
1 stop10h 50m
JetBlue
Deal found 7/17$704
This lol.travel deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:05 pm
MAD
-
CHS
1 stop33h 55m
JetBlue
Mon 9/76:42 pm
CHS
-
MAD
1 stop10h 48m
JetBlue
Deal found 7/17$736
This lol.travel deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:00 pm
MAD
-
CLT
Nonstop9h 20m
Finnair
Wed 9/98:35 am
CLT
-
MAD
1 stop15h 00m
Finnair
Deal found 7/18$764
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am
MAD
-
GSP
2 stops21h 26m
Delta
Wed 9/166:57 pm
GSP
-
MAD
2 stops14h 38m
Delta
Deal found 7/15$769
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
MAD
-
GSP
2 stops17h 46m
Delta
Thu 9/246:57 pm
GSP
-
MAD
2 stops15h 48m
Delta
Deal found 7/19$771
This KLM deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
MAD
-
CHS
2 stops16h 32m
Multiple Airlines
Thu 9/2412:55 pm
CHS
-
MAD
2 stops14h 15m
Multiple Airlines
Deal found 7/19$771
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:00 am
MAD
-
CHS
2 stops19h 50m
Delta
Mon 9/76:43 pm
CHS
-
MAD
2 stops16h 02m
Delta
Deal found 7/17$772
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:05 am
MAD
-
CHS
2 stops20h 37m
Delta
Sun 11/85:30 am
CHS
-
MAD
2 stops20h 30m
Delta
Deal found 7/19$774
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:50 am
MAD
-
CHS
1 stop16h 54m
Delta
Wed 9/235:33 pm
CHS
-
MAD
2 stops17h 12m
Delta
Deal found 7/19$776
This Air France deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1810:05 am
MAD
-
CHS
2 stops16h 10m
Air France
Thu 9/2412:55 pm
CHS
-
MAD
2 stops14h 15m
Air France
Deal found 7/19$777

Find flight deals from Madrid to South Carolina

Keep the following information in mind while searching for Madrid to South Carolina flight deals. Data was last updated July 20, 2026.

Round-trip from

$652
(Ovago)

One-way from

$379
(lol.travel)
From Madrid Barajas to South Carolina
Search Deals
One-way flight from Madrid Barajas to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 20, 2026.
Use the filters below to find and compare flights from Madrid to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Wed 9/16

6:00 am-4:32 pm

2 stops16h 32m

Charleston

Thu 9/24

12:55 pm-9:10 am

2 stops14h 15m

$771

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 9/17

6:00 am-4:28 pm

2 stops16h 28m

Charleston

Fri 9/25

3:15 pm-11:20 am

2 stops14h 05m

$771

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Sun 11/1

6:05 am-9:42 pm

2 stops20h 37m

Charleston

Sun 11/8

5:30 am-8:00 am

2 stops20h 30m

$774

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Wed 9/16

9:50 am-8:37 pm

1 stop16h 47m

Greenville

Thu 9/24

6:57 pm-3:35 pm

2 stops14h 38m

$776

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Wed 9/16

9:50 am-8:44 pm

1 stop16h 54m

Charleston

Wed 9/23

5:33 pm-4:45 pm

2 stops17h 12m

$776

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Thu 9/10

1:00 pm-4:15 pm

Nonstop9h 15m

Charlotte Douglas

Mon 9/14

8:25 pm-9:40 am

1 stop31h 15m

$815
Quickest round-trip

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Thu 10/15

12:40 pm-4:00 pm

Nonstop9h 20m

Charlotte Douglas

Thu 10/29

4:45 pm-5:45 am

Nonstop8h 00m

$824

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Thu 8/27

1:00 pm-4:20 pm

Nonstop9h 20m

Charlotte Douglas

Wed 9/9

4:15 pm-10:15 am

1 stop12h 00m

$825

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Thu 8/27

1:00 pm-4:20 pm

Nonstop9h 20m

Charlotte Douglas

Wed 9/9

8:35 am-5:35 am

1 stop15h 00m

$827

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Thu 10/15

6:00 am-6:35 pm

2 stops18h 35m

Charlotte Douglas

Sat 10/24

1:09 pm-12:30 pm

2 stops17h 21m

$828

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/18

Showing 1-10 of 56 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Madrid to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to South Carolina

What is the cheapest month to book a flight from Madrid to South Carolina?

Currently, March is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $701). Flying from Madrid to South Carolina in December is currently the most expensive (average of $1,230). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Madrid to South Carolina?

Related info for your journey

Find useful and relevant information for your journey from Madrid to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madrid to South Carolina?

    Madrid Barajas (MAD) is the airport you will fly out of if you book a flight from Madrid to South Carolina. It is only a 8.5 mi journey to Barajas (MAD) from Madrid’s city center.

  • How long is the flight from Madrid to South Carolina?

    A quick flight from Madrid to South Carolina can take about 9h 15m. JetBlue provides one of the quickest options available for as low as $815. Madrid and South Carolina are separated by a distance of 4096 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madrid to South Carolina?

    When deciding which route to take from Madrid to South Carolina consider Madrid Barajas - Charlotte Douglas, Madrid Barajas - Charleston or Madrid Barajas - Savannah/Hilton Head as they are the most popular.

  • Can I find deals for flights from Madrid to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madrid to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to South Carolina.

  • Can I find deals for business class flights from Madrid to South Carolina?

    Yes. Cheapflights offers flight deals from Madrid to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to South Carolina?

    Currently, March is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $701). Flying from Madrid to South Carolina in December is currently the most expensive (average of $1,230). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.