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South Carolina

$307+ Cheap flights from Madrid, Spain (MAD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — CHS
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Madrid to South Carolina

Cheapest flights from Madrid to South Carolina
Explore the most affordable flight options available from Madrid to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Iberia deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/101:00 pmMAD - CLT
Nonstop9h 25mIberia
Thu 2/58:25 pmCLT - MAD
1 stop11h 50mIberia
Deal found 12/2$664
This Cheapflightsfares deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/101:00 pmMAD - CLT
Nonstop9h 25mFinnair
Thu 2/54:10 pmCLT - MAD
Nonstop7h 35mFinnair
Deal found 12/2$674
This Iberia deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2912:30 pmMAD - CLT
1 stop13h 32mIberia
Thu 1/228:25 pmCLT - MAD
1 stop11h 50mIberia
Deal found 12/2$693
This British Airways deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/151:00 pmMAD - CLT
Nonstop9h 25mBritish Airways
Fri 3/64:27 pmCLT - MAD
1 stop10h 28mBritish Airways
Deal found 12/2$695
This Iberia deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:00 pmMAD - CLT
Nonstop9h 20mIberia
Sun 1/116:25 pmCLT - MAD
1 stop31h 30mIberia
Deal found 12/2$718
This Rumbo deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:15 amMAD - CHS
1 stop14h 05mVirgin Atlantic
Fri 1/166:00 amCHS - MAD
1 stop20h 00mVirgin Atlantic
Deal found 12/4$802
This KLM deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2911:15 amMAD - CLT
1 stop15h 04mMultiple Airlines
Thu 1/226:53 pmCLT - MAD
2 stops14h 27mMultiple Airlines
Deal found 12/2$819
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2911:15 amMAD - CLT
1 stop16h 56mDelta
Thu 1/222:25 pmCLT - MAD
1 stop11h 35mDelta
Deal found 12/3$822
This KLM deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:15 amMAD - CHS
1 stop27h 27mMultiple Airlines
Fri 1/1612:00 pmCHS - MAD
2 stops15h 10mMultiple Airlines
Deal found 12/4$822
This Delta deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:00 amMAD - CHS
2 stops20h 39mDelta
Fri 1/1612:00 pmCHS - MAD
2 stops17h 30mDelta
Deal found 12/4$895
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:15 amMAD - MYR
1 stop31h 20mUnited Airlines
Mon 12/151:16 pmMYR - MAD
1 stop13h 59mUnited Airlines
Deal found 12/4$1,035
This Delta deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:15 amMAD - MYR
1 stop12h 46mDelta
Mon 12/152:40 pmMYR - MAD
2 stops18h 40mDelta
Deal found 12/4$1,093

Find flight deals from Madrid to South Carolina

Keep the following information in mind while searching for Madrid to South Carolina flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$552
(Mytrip)

One-way from

$307
(Kiwi.com)
Provider with most accurate pricing for Madrid Barajas-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Madrid Barajas-Myrtle Beach Intl flights.
Search Deals
From Madrid Barajas to South Carolina
Search Deals
One-way flight from Madrid Barajas to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Madrid to South Carolina that are best for you.

Fly from

Madrid

Fly to

South Carolina

Route

Depart

Return

Price

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Sun 1/18

12:10 pm-4:10 pm

2 stops34h 00m

Charleston

Sun 1/25

5:05 pm-5:10 pm

2 stops18h 05m

$560

MadridCharlotte

MAD - CLT

MADCLT

Madrid Barajas

Fri 1/16

1:15 pm-9:42 pm

1 stop14h 27m

Charlotte Douglas

Fri 1/23

6:30 pm-12:40 pm

1 stop12h 10m

$675

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 1/15

2:55 pm-5:36 pm

3 stops32h 41m

Charleston

Mon 1/19

5:05 pm-8:20 pm

3 stops21h 15m

$729

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 1/15

6:00 am-5:59 pm

2 stops17h 59m

Charleston

Mon 1/19

6:00 am-9:15 am

1 stop21h 15m

$740

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Tue 2/3

11:00 am-10:24 pm

2 stops17h 24m

Greenville

Tue 2/10

3:05 pm-11:30 am

2 stops14h 25m

$745

MadridGreenville

MAD - GSP

MADGSP

Madrid Barajas

Tue 2/3

12:40 pm-8:48 pm

1 stop14h 08m

Greenville

Tue 2/10

7:00 am-5:50 am

1 stop16h 50m

$753

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 1/15

12:40 pm-9:11 pm

1 stop14h 31m

Charleston

Mon 1/19

10:59 am-8:55 am

1 stop15h 56m

$756

MadridCharleston

MAD - CHS

MADCHS

Madrid Barajas

Thu 2/19

11:15 am-6:12 pm

1 stop12h 57m

Charleston

Mon 2/23

6:00 am-9:15 am

2 stops21h 15m

$756

MadridMyrtle Beach

MAD - MYR

MADMYR

Madrid Barajas

Wed 2/18

11:00 am-12:11 pm

2 stops31h 11m

Myrtle Beach Intl

Sun 2/22

6:00 am-3:20 pm

2 stops27h 20m

$768

MadridMyrtle Beach

MAD - MYR

MADMYR

Madrid Barajas

Wed 2/18

10:00 am-11:57 pm

2 stops19h 57m

Myrtle Beach Intl

Sun 2/22

10:31 am-9:15 am

1 stop16h 44m

$776

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 53 results
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Best time to book a flight from Madrid to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to South Carolina

What is the cheapest month to book a flight from Madrid to South Carolina?

Currently, January is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $579). Flying from Madrid to South Carolina in July is currently the most expensive (average of $923). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Madrid to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madrid to South Carolina?

    Madrid Barajas (MAD) is the airport you will fly out of if you book a flight from Madrid to South Carolina. It is only a 8.5 mi journey to Barajas (MAD) from Madrid’s city center.

  • How long is the flight from Madrid to South Carolina?

    A quick flight from Madrid to South Carolina can take about 14h 08m. British Airways provides one of the quickest options available for as low as $753. Madrid and South Carolina are separated by a distance of 4169 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Madrid to South Carolina?

    When deciding which route to take from Madrid to South Carolina consider Madrid Barajas - Charlotte Douglas, Madrid Barajas - Charleston or Madrid Barajas - Greenville as they are the most popular.

  • Can I find deals for flights from Madrid to South Carolina that include hotel bookings?

    Yes. In addition to deals on Madrid to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to South Carolina.

  • Can I find deals for business class flights from Madrid to South Carolina?

    Yes. Cheapflights offers flight deals from Madrid to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Madrid to South Carolina (average of $579). Flying from Madrid to South Carolina in July is currently the most expensive (average of $923). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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