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South Carolina

$54+ Cheap flights from Islip, NY (ISP) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — CHS
Apr 14 — Apr 211
Tue 4/14
Tue 4/21
1 adult, Economy
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Cheap flight deals from Islip to South Carolina

Cheapest flights from Islip to South Carolina
Explore the most affordable flight options available from Islip to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.

This Frontier deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:38 pm
ISP
-
MYR
Nonstop1h 43m
Frontier
Sat 6/134:11 pm
MYR
-
ISP
Nonstop1h 54m
Frontier
Deal found 3/11$108
This Booking.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:45 pm
ISP
-
CHS
Nonstop2h 12m
Breeze Airways
Fri 4/246:11 pm
CHS
-
ISP
Nonstop1h 54m
Breeze Airways
Deal found 3/13$115
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:09 pm
ISP
-
MYR
Nonstop1h 55m
Breeze Airways
Wed 6/173:39 pm
MYR
-
ISP
Nonstop1h 50m
Breeze Airways
Deal found 3/11$117
This Booking.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:43 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Fri 5/151:13 pm
CHS
-
ISP
Nonstop1h 57m
Breeze Airways
Deal found 3/14$120
This CheapOair deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:09 pm
ISP
-
MYR
Nonstop1h 55m
Breeze Airways
Sat 6/133:39 pm
MYR
-
ISP
Nonstop1h 50m
Breeze Airways
Deal found 3/15$122
This CheapOair deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:45 pm
ISP
-
CHS
Nonstop2h 12m
Breeze Airways
Fri 4/176:11 pm
CHS
-
ISP
Nonstop1h 54m
Breeze Airways
Deal found 3/12$122
This CheapOair deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:09 pm
ISP
-
MYR
Nonstop1h 55m
Breeze Airways
Wed 6/243:39 pm
MYR
-
ISP
Nonstop1h 50m
Breeze Airways
Deal found 3/13$127
This CheapOair deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:43 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Sat 5/911:36 am
CHS
-
ISP
Nonstop1h 57m
Breeze Airways
Deal found 3/15$127
This Booking.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:43 pm
ISP
-
CHS
Nonstop2h 08m
Breeze Airways
Mon 6/156:06 pm
CHS
-
ISP
Nonstop1h 57m
Breeze Airways
Deal found 3/15$130
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:09 pm
ISP
-
MYR
Nonstop1h 55m
Breeze Airways
Sat 5/303:39 pm
MYR
-
ISP
Nonstop1h 50m
Breeze Airways
Deal found 3/12$132
This CheapOair deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:45 pm
ISP
-
CHS
Nonstop2h 12m
Breeze Airways
Fri 4/246:11 pm
CHS
-
ISP
Nonstop1h 54m
Breeze Airways
Deal found 3/12$132
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:45 pm
ISP
-
CHS
Nonstop2h 12m
Breeze Airways
Fri 4/176:11 pm
CHS
-
ISP
Nonstop1h 54m
Breeze Airways
Deal found 3/12$137

Find flight deals from Islip to South Carolina

Keep the following information in mind while searching for Islip to South Carolina flight deals. Data was last updated March 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$108
(Frontier)

One-way from

$54
(Priceline)

Popular in

April

Cheapest in

September

Average price

$258

Good round-trip deal

$158 or less

Good one-way deal

$105 or less
Provider with most accurate pricing for New York (NYC)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York (NYC)-Myrtle Beach Intl flights.
Search Deals
From Islip Long Island to South Carolina
Search Deals
One-way flight from Islip Long Island to South Carolina
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Islip Long Island to South Carolina.
Search Deals
Price to beat on a one-way flight from Islip Long Island to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Islip to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Wed 6/3

4:10 pm-8:45 pm

1 stop4h 35m

Charlotte Douglas

Mon 6/8

7:50 pm-11:35 pm

1 stop3h 45m

$187

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Wed 4/22

12:30 pm-5:45 pm

1 stop5h 15m

Charlotte Douglas

Mon 4/27

7:20 pm-11:30 pm

1 stop4h 10m

$187

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Wed 4/22

4:10 pm-8:45 pm

1 stop4h 35m

Charlotte Douglas

Sat 4/25

7:05 am-11:35 am

1 stop4h 30m

$197

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Mon 4/27

8:35 am-6:45 pm

2 stops10h 10m

Charlotte Douglas

Wed 4/29

5:35 pm-10:10 pm

1 stop4h 35m

$202

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Wed 5/6

4:10 pm-8:45 pm

1 stop4h 35m

Charlotte Douglas

Thu 5/14

7:20 pm-11:30 pm

1 stop4h 10m

$238

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Fri 7/17

8:43 pm-10:51 pm

Nonstop2h 08m

Charleston

Sun 7/19

3:53 pm-7:09 pm

1 stop3h 16m

$241

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Fri 4/10

8:45 pm-10:57 pm

Nonstop2h 12m

Charleston

Mon 4/13

6:11 pm-8:05 pm

Nonstop1h 54m

$260

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Fri 4/17

12:30 pm-6:20 pm

1 stop5h 50m

Charlotte Douglas

Mon 4/20

7:20 pm-11:30 pm

1 stop4h 10m

$263

IslipCharlotte

ISP - CLT

ISPCLT

Islip Long Island

Sun 4/12

6:05 am-10:10 am

1 stop4h 05m

Charlotte Douglas

Mon 4/13

7:20 pm-11:30 pm

1 stop4h 10m

$263
Quickest round-trip

IslipCharleston

ISP - CHS

ISPCHS

Islip Long Island

Fri 5/15

3:50 pm-5:58 pm

Nonstop2h 08m

Charleston

Mon 5/18

6:06 pm-8:03 pm

Nonstop1h 57m

$278

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/13

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
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6

Best time to book a flight from Islip to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to South Carolina

What is the cheapest month to book a flight from Islip, New York to South Carolina?

Currently, April is the cheapest month in which you can book a flight from Islip, New York to South Carolina (average of $53). Flying from Islip, New York to South Carolina in July is currently the most expensive (average of $79). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ISP to SC?

Find hourly flight availability from Islip to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 15, 2026.

Unlike at noon, when flights are generally more expensive, you can save up to 36% on flights from Islip, New York to South Carolina by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Islip, New York to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Islip to South Carolina. Price data was last updated on March 14, 2026.

Travelers seeking maximum savings on their Islip, New York to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Islip, New York to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 15, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andJetBlue from Islip to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
271 reviews

Boarding

8.3

Overall

8.1

Entertainment

6.6

Food

6.6

Crew

8.7

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.1
Very good
271 reviews
Breeze Airways
8.1
Very good
271 reviews

Boarding

8.3

Overall

8.1

Entertainment

6.6

Food

6.6

Crew

8.7

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Southwest
8.0
Very good
4,318 reviews
Breeze Airways
8.1
Very good
271 reviews

Boarding

8.3

Overall

8.1

Entertainment

6.6

Food

6.6

Crew

8.7

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
JetBlue
7.2
Good
2,906 reviews
Breeze Airways
8.1
Very good
271 reviews

Boarding

8.3

Overall

8.1

Entertainment

6.6

Food

6.6

Crew

8.7

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Frontier
5.7
Fair
3,030 reviews
Breeze Airways
8.1
Very good
271 reviews

Boarding

8.3

Overall

8.1

Entertainment

6.6

Food

6.6

Crew

8.7

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Islip to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Islip to South Carolina?

    For a flight from Islip to South Carolina, you will be flying from Long Island. Islip Long Island (ISP) is just 7.2 mi from the center of the city.

  • How popular is this Islip, New York to South Carolina flight route?

    This flight path from Islip Long Island to South Carolina was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Islip, New York to South Carolina?

    Departing from Islip, New York to South Carolina will take you 2h 08m. There are 666 mi between Islip, New York and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Islip, New York to South Carolina?

    The most popular flight routes from Islip, New York to South Carolina are Islip Long Island - Charleston, Islip Long Island - Myrtle Beach Intl and Islip Long Island - Charlotte Douglas.

  • What are the cheapest flights from Islip, New York to South Carolina?

    On average you can expect to pay $199 for a flight from Islip, New York to South Carolina. The cheapest flight overall is $102 while the most popular route, (Islip Long Island - Charleston) is currently priced at $115.

  • Can I find deals for flights from Islip to South Carolina that include hotel bookings?

    Yes. In addition to deals on Islip to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to South Carolina.

  • Can I find deals for business class flights from Islip to South Carolina?

    Yes. Cheapflights offers flight deals from Islip to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to South Carolina?

    Currently, April is the cheapest month in which you can book a flight from Islip, New York to South Carolina (average of $53). Flying from Islip, New York to South Carolina in July is currently the most expensive (average of $79). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Islip to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Islip to South Carolina

Discover the top 4 airlines that operate flights from Islip to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$98Average$228FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$108Average$191FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$162Average$362FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$226Average$416FlexibilityNo cancel feeOn-time63%

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