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South Carolina

$185+ Cheap flights from Gainesville (GNV) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — CHS
Jan 2 — Jan 91
Fri 1/2
Fri 1/9
1 adult, Economy
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Cheap flight deals from Gainesville to South Carolina

Cheapest flights from Gainesville to South Carolina
Explore the most affordable flight options available from Gainesville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 3, 2025.

This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/161:43 pmGNV - CLT
1 stop4h 45mDelta
Thu 1/16:00 amCLT - GNV
1 stop3h 28mDelta
Deal found 12/2$320
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:45 amGNV - CLT
1 stop4h 08mDelta
Sat 1/36:00 amCLT - GNV
1 stop3h 28mDelta
Deal found 12/2$335
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:15 pmGNV - CLT
1 stop4h 55mDelta
Wed 12/317:05 amCLT - GNV
1 stop4h 15mDelta
Deal found 12/2$347
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:00 amGNV - CLT
1 stop4h 45mDelta
Sat 1/36:00 amCLT - GNV
1 stop3h 28mDelta
Deal found 12/2$350
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/167:04 pmGNV - CLT
1 stop4h 38mDelta
Wed 12/317:05 amCLT - GNV
1 stop4h 15mDelta
Deal found 12/2$352
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:40 pmGNV - CLT
Nonstop1h 50mAmerican Airlines
Sat 1/38:58 pmCLT - GNV
Nonstop1h 42mAmerican Airlines
Deal found 12/2$360
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:40 pmGNV - CLT
Nonstop1h 50mAmerican Airlines
Thu 1/18:58 pmCLT - GNV
Nonstop1h 42mAmerican Airlines
Deal found 12/2$380
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amGNV - CLT
1 stop3h 48mDelta
Thu 1/16:00 amCLT - GNV
1 stop3h 28mDelta
Deal found 12/2$387
This Delta deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:00 amGNV - CLT
1 stop4h 45mDelta
Sat 12/206:00 amCLT - GNV
1 stop3h 28mDelta
Deal found 12/1$392
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1710:10 amGNV - MYR
1 stop3h 45mDelta
Sun 12/216:00 amMYR - GNV
1 stop5h 20mDelta
Deal found 12/2$407
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amGNV - MYR
2 stops8h 44mAmerican Airlines
Sun 12/216:00 amMYR - GNV
1 stop4h 52mAmerican Airlines
Deal found 12/2$412
This Delta deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amGNV - MYR
1 stop3h 35mDelta
Wed 12/1710:32 amMYR - GNV
1 stop4h 24mDelta
Deal found 11/30$421

Find flight deals from Gainesville to South Carolina

Keep the following information in mind while searching for Gainesville to South Carolina flight deals. Data was last updated December 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$215
(American Airlines)

One-way from

$185
(Delta)
Provider with most accurate pricing for Gainesville Regional-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Myrtle Beach Intl flights.
Search Deals
From Gainesville Regional to South Carolina
Search Deals
One-way flight from Gainesville Regional to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from Gainesville to South Carolina that are best for you.

Fly from

Gainesville

Fly to

South Carolina

Route

Depart

Return

Price

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Fri 1/30

6:58 pm-8:44 pm

Nonstop1h 46m

Charlotte Douglas

Sun 2/1

9:45 pm-11:30 pm

Nonstop1h 45m

$215

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Fri 1/16

6:35 am-8:19 am

Nonstop1h 44m

Charlotte Douglas

Sun 1/18

9:45 pm-11:30 pm

Nonstop1h 45m

$215

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Sat 1/31

6:35 am-8:19 am

Nonstop1h 44m

Charlotte Douglas

Sun 2/1

9:45 pm-11:30 pm

Nonstop1h 45m

$215

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Sat 2/21

10:13 am-4:04 pm

1 stop5h 51m

Charlotte Douglas

Sat 2/28

6:59 pm-10:42 pm

1 stop3h 43m

$235

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Fri 1/16

2:12 pm-6:10 pm

1 stop3h 58m

Charlotte Douglas

Mon 1/19

5:25 am-9:24 am

1 stop3h 59m

$235

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Fri 1/30

10:11 am-4:02 pm

1 stop5h 51m

Charlotte Douglas

Sun 2/1

1:13 pm-6:10 pm

1 stop4h 57m

$235

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Fri 1/16

6:35 am-8:19 am

Nonstop1h 44m

Charlotte Douglas

Mon 1/19

6:55 pm-11:57 pm

1 stop5h 02m

$235

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Fri 1/16

10:11 am-4:02 pm

1 stop5h 51m

Charlotte Douglas

Sun 1/18

4:54 pm-10:29 pm

1 stop5h 35m

$235

GainesvilleCharlotte

GNV - CLT

GNVCLT

Gainesville Regional

Fri 2/20

6:00 am-11:36 am

1 stop5h 36m

Charlotte Douglas

Sat 2/21

8:50 pm-10:36 pm

Nonstop1h 46m

$235

GainesvilleGreenville

GNV - GSP

GNVGSP

Gainesville Regional

Sat 1/31

6:00 am-11:08 am

1 stop5h 08m

Greenville

Wed 2/4

6:50 am-12:26 pm

1 stop5h 36m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/30

Showing 1-10 of 25 results
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Best time to book a flight from Gainesville to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to South Carolina

What is the cheapest month to book a flight from Gainesville to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Gainesville to South Carolina (average of $42). Flying from Gainesville to South Carolina in January is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to SC?

Find hourly flight availability from Gainesville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 3, 2025.

It’s optimal to fly from Gainesville to South Carolina at noon. By choosing this option you can save up to 36% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 3, 2025.
Read through reviews of airlines operating flights from Gainesville to South Carolina, such as Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Gainesville to South Carolina?

    If you book a flight to South Carolina from Gainesville, you will be flying from Gainesville Regional, which is the city’s only airport. Gainesville Regional (GNV) is located 4.2 mi from the center of Gainesville.

  • How long is the flight from Gainesville to South Carolina?

    Departing from Gainesville to South Carolina will take you 1h 46m. The distance between Gainesville and South Carolina is about 390 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Gainesville to South Carolina?

    Most travelers choose Gainesville Regional - Charlotte Douglas, Gainesville Regional - Greenville or Gainesville Regional - Myrtle Beach Intl when deciding on the best route from Gainesville to South Carolina.

  • Can I find deals for flights from Gainesville to South Carolina that include hotel bookings?

    Yes. In addition to deals on Gainesville to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to South Carolina.

  • Can I find deals for business class flights from Gainesville to South Carolina?

    Yes. Cheapflights offers flight deals from Gainesville to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Gainesville to South Carolina (average of $42). Flying from Gainesville to South Carolina in January is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Gainesville to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Gainesville to South Carolina

Discover the top airline that operate flights from Gainesville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$351Average$442FlexibilityNo cancel feeOn-timeN/A

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