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South Carolina

$67+ Cheap flights from Midway (MDW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — CHS
Dec 30 — Jan 61
Tue 12/30
Tue 1/6
1 adult, Economy
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Cheap flight deals from Midway to South Carolina

Keep the following information in mind while searching for Midway to South Carolina flight deals. Data was last updated November 30, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$162
(Expedia)

One-way from

$67
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$412

Good round-trip deal

$399 or less

Good one-way deal

$198 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
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From Chicago Midway to South Carolina
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One-way flight from Chicago Midway to South Carolina
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Highest demand for flights based on searches. 9% potential increase in price ($33 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Price to beat on a round-trip flight from Chicago Midway to South Carolina.
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Price to beat on a one-way flight from Chicago Midway to South Carolina.
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Find flight deals from Midway to South Carolina

Cheapest flights from Midway to South Carolina
Explore the most affordable flight options available from Midway to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 30, 2025.

This CheapOair deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:59 pmMDW - CLT
1 stop20h 42mFrontier
Sun 12/219:33 pmCLT - MDW
1 stop25h 25mFrontier
Deal found 11/28$164
This Southwest deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:30 pmMDW - CLT
Nonstop1h 50mSouthwest
Thu 1/85:50 pmCLT - MDW
Nonstop2h 05mSouthwest
Deal found 11/29$169
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:52 pmMDW - CLT
1 stop27h 08mMultiple Airlines
Mon 12/159:20 pmCLT - MDW
2 stops36h 26mMultiple Airlines
Deal found 11/30$177
This CheapOair deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:05 amMDW - CLT
1 stop9h 22mFrontier
Mon 12/1510:32 amCLT - MDW
1 stop12h 26mFrontier
Deal found 11/27$187
This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/153:10 pmMDW - CLT
1 stop17h 40mMultiple Airlines
Tue 12/239:38 pmCLT - MDW
2 stops16h 43mMultiple Airlines
Deal found 11/29$192
This Frontier deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:05 amMDW - CLT
1 stop11h 11mFrontier
Mon 12/83:07 pmCLT - MDW
1 stop8h 11mFrontier
Deal found 11/27$204
This Kiwi.com deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:15 amMDW - CLT
2 stops53h 26mMultiple Airlines
Thu 12/189:34 pmCLT - MDW
1 stop25h 24mMultiple Airlines
Deal found 11/28$205
This Mytrip deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:05 amMDW - CLT
1 stop11h 11mFrontier
Fri 12/53:07 pmCLT - MDW
1 stop7h 21mFrontier
Deal found 11/27$208
This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:44 amMDW - MYR
1 stop23h 16mMultiple Airlines
Thu 12/189:54 amMYR - MDW
2 stops13h 04mMultiple Airlines
Deal found 11/29$217
This Kiwi.com deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:44 amMDW - MYR
2 stops9h 04mMultiple Airlines
Wed 12/109:05 amMYR - MDW
1 stop28h 56mMultiple Airlines
Deal found 11/28$228
This Southwest deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:50 amMDW - GSP
1 stop6h 15mSouthwest
Tue 2/1010:05 amGSP - MDW
1 stop5h 50mSouthwest
Deal found 11/28$233
This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:44 amMDW - MYR
1 stop15h 15mMultiple Airlines
Tue 12/239:54 amMYR - MDW
2 stops13h 04mMultiple Airlines
Deal found 11/29$259

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 30, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South Carolina that are best for you.

Fly from

Midway

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 1/13

6:45 am-1:38 pm

1 stop5h 53m

Charlotte Douglas

Tue 1/20

9:30 am-12:51 pm

1 stop4h 21m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 1/9

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Sun 1/11

6:20 pm-7:25 pm

Nonstop2h 05m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 1/28

6:00 am-1:38 pm

1 stop6h 38m

Charlotte Douglas

Sun 2/1

6:00 am-8:52 am

1 stop3h 52m

$187

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 1/9

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Mon 1/12

5:50 pm-6:55 pm

Nonstop2h 05m

$188

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sun 1/11

9:32 am-4:05 pm

1 stop5h 33m

Charlotte Douglas

Mon 1/12

6:59 pm-10:07 pm

1 stop4h 08m

$197

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 1/9

6:45 am-1:38 pm

1 stop5h 53m

Charlotte Douglas

Sun 1/11

6:00 am-8:52 am

1 stop3h 52m

$197

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Wed 4/15

6:00 am-1:56 pm

1 stop6h 56m

Greenville

Sat 4/18

5:45 am-9:51 am

1 stop5h 06m

$215

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Sat 1/17

11:21 am-4:53 pm

1 stop4h 32m

Greenville

Wed 1/21

7:20 am-12:49 pm

1 stop6h 29m

$215

ChicagoMyrtle Beach

MDW - MYR

MDWMYR

Chicago Midway

Sun 12/14

7:44 am-8:00 am

1 stop23h 16m

Myrtle Beach Intl

Thu 12/18

9:54 am-9:58 pm

2 stops13h 04m

$217

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Tue 4/14

6:00 am-1:56 pm

1 stop6h 56m

Greenville

Sun 4/19

5:45 am-9:51 am

1 stop5h 06m

$222

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/29

Showing 1-10 of 60 results
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Best time to book a flight from Midway to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South Carolina

What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $379). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDW to SC?

Find hourly flight availability from Midway to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Chicago Midway Airport to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 39% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Chicago Midway Airport to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Midway to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Chicago Midway Airport to South Carolina flight should consider departing on Saturday afternoons when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 30, 2025.
Read through reviews of airlines operating flights from Chicago Midway Airport to South Carolina, such as Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,251 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,011 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from Midway to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to South Carolina?

    Airlines like Delta and Southwest fly from Chicago Midway Airport to South Carolina in about 1h 50m. The time it takes to get you to your destination can typically vary by up to 4h 03m. The distance from Chicago Midway Airport to South Carolina is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Chicago Midway Airport to South Carolina?

    While some choose either Chicago Midway - Charleston or Chicago Midway - Myrtle Beach Intl, Chicago Midway - Charlotte Douglas is the most popular route from Chicago Midway Airport to South Carolina.

  • What are the cheapest flights from Chicago Midway Airport to South Carolina?

    On average you can expect to pay $562 for a flight from Chicago Midway Airport to South Carolina. The cheapest flight overall is $364 while the most popular route, (Chicago Midway - Charlotte Douglas) is currently priced at $163.

  • Can I find deals for flights from Midway to South Carolina that include hotel bookings?

    Yes. In addition to deals on Midway to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South Carolina.

  • Can I find deals for business class flights from Midway to South Carolina?

    Yes. Cheapflights offers flight deals from Midway to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $379). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Midway to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Midway to South Carolina

Discover the top 2 airlines that operate flights from Midway to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$214Average$374FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$217Average$360FlexibilityNo cancel feeOn-time63%

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