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$55+ Cheap flights from Midway (MDW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — CHS
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from Midway to South Carolina

Keep the following information in mind while searching for Midway to South Carolina flight deals. Data was last updated November 6, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$110
(CheapOair)

One-way from

$55
(Priceline)

Popular in

November

Cheapest in

January

Average price

$407

Good round-trip deal

$339 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
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From Chicago Midway to South Carolina
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One-way flight from Chicago Midway to South Carolina
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Highest demand for flights based on searches. 14% potential increase in price ($54 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Price to beat on a round-trip flight from Chicago Midway to South Carolina.
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Find flight deals from Midway to South Carolina

Cheapest flights from Midway to South Carolina
Explore the most affordable flight options available from Midway to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This CheapOair deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/83:10 pmMDW - CLT
1 stop17h 40mFrontier
Thu 12/1110:33 pmCLT - MDW
1 stop25h 06mFrontier
Deal found 11/6$110
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:05 amMDW - CLT
1 stop9h 22mFrontier
Mon 12/153:07 pmCLT - MDW
1 stop8h 11mFrontier
Deal found 11/4$124
This Booking.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:41 pmMDW - CLT
1 stop10h 13mFrontier
Fri 11/2111:56 amCLT - MDW
1 stop12h 33mFrontier
Deal found 11/4$128
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:05 amMDW - CLT
1 stop9h 22mFrontier
Sun 12/143:07 pmCLT - MDW
1 stop6h 38mFrontier
Deal found 11/4$138
This Booking.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:05 amMDW - CLT
1 stop9h 22mFrontier
Sun 12/75:44 pmCLT - MDW
1 stop18h 24mFrontier
Deal found 11/4$139
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2312:25 pmMDW - CLT
1 stop21h 36mFrontier
Thu 11/2710:47 amCLT - MDW
1 stop6h 43mFrontier
Deal found 11/3$141
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/62:59 pmMDW - CLT
1 stop20h 42mFrontier
Sun 12/75:44 pmCLT - MDW
1 stop18h 24mFrontier
Deal found 11/4$142
This Booking.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:59 pmMDW - CLT
1 stop20h 42mFrontier
Sun 12/143:07 pmCLT - MDW
1 stop6h 38mFrontier
Deal found 11/5$143
This Frontier deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/228:29 pmMDW - CLT
1 stop10h 25mFrontier
Wed 11/2610:13 amCLT - MDW
1 stop7h 44mFrontier
Deal found 11/6$144
This Booking.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2312:25 pmMDW - CLT
1 stop21h 36mFrontier
Mon 11/243:00 pmCLT - MDW
1 stop8h 17mFrontier
Deal found 11/4$145
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:20 amMDW - MYR
1 stop12h 34mMultiple Airlines
Mon 11/246:15 amMYR - MDW
2 stops12h 00mMultiple Airlines
Deal found 11/5$235
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:05 amMDW - CHS
2 stops24h 21mMultiple Airlines
Mon 11/246:13 pmCHS - MDW
1 stop18h 29mMultiple Airlines
Deal found 11/6$235

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South Carolina that are best for you.

Fly from

Midway

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 12/2

6:00 pm-8:50 pm

Nonstop1h 50m

Charlotte Douglas

Tue 12/9

6:10 am-7:15 am

Nonstop2h 05m

$149

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 12/10

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Thu 12/11

6:10 am-7:15 am

Nonstop2h 05m

$151

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 12/11

6:00 pm-8:50 pm

Nonstop1h 50m

Charlotte Douglas

Mon 12/15

8:30 am-1:45 pm

1 stop6h 15m

$173

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Mon 12/8

8:10 am-5:40 pm

1 stop8h 30m

Charlotte Douglas

Thu 12/11

6:10 am-7:15 am

Nonstop2h 05m

$173

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 12/4

11:25 am-5:40 pm

1 stop5h 15m

Charlotte Douglas

Mon 12/8

6:10 am-7:15 am

Nonstop2h 05m

$173

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 2/24

6:00 am-11:02 am

1 stop4h 02m

Charlotte Douglas

Wed 2/25

6:00 am-8:54 am

1 stop3h 54m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 12/5

11:25 am-5:40 pm

1 stop5h 15m

Charlotte Douglas

Sun 12/7

5:50 am-6:50 am

Nonstop2h 00m

$183

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 12/12

9:10 am-7:00 pm

1 stop8h 50m

Charlotte Douglas

Mon 12/15

8:30 am-1:00 pm

2 stops5h 30m

$194

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 12/4

11:25 am-5:40 pm

1 stop5h 15m

Charlotte Douglas

Sun 12/7

5:50 am-6:50 am

Nonstop2h 00m

$200

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 11/19

6:00 am-10:55 am

1 stop3h 55m

Charlotte Douglas

Thu 11/27

6:00 am-8:54 am

1 stop3h 54m

$213

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 60 results
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6

Best time to book a flight from Midway to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South Carolina

What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $163). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $379). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDW to SC?

Find hourly flight availability from Midway to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

A simple way to save on the total cost of your ticket is to fly from Chicago Midway Airport to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 42% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Chicago Midway Airport to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Midway to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Chicago Midway Airport to South Carolina flight should consider departing on Saturday afternoons when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 6, 2025.
Read through reviews of airlines operating flights from Chicago Midway Airport to South Carolina, such as Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Midway to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to South Carolina?

    Airlines like Southwest and Delta fly from Chicago Midway Airport to South Carolina in about 1h 50m. The time it takes to get you to your destination can typically vary by up to 3h 21m. The distance from Chicago Midway Airport to South Carolina is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Chicago Midway Airport to South Carolina one-way?

    The cheapest airlines for a one-way flight from Chicago Midway Airport to South Carolina are Southwest ($70), Frontier ($76), and Delta ($108).

  • What are the most popular routes from Chicago Midway Airport to South Carolina?

    While some choose either Chicago Midway - Charleston or Chicago Midway - Savannah/Hilton Head, Chicago Midway - Charlotte Douglas is the most popular route from Chicago Midway Airport to South Carolina.

  • What are the cheapest flights from Chicago Midway Airport to South Carolina?

    On average you can expect to pay $549 for a flight from Chicago Midway Airport to South Carolina. The cheapest flight overall is $399 while the most popular route, (Chicago Midway - Charlotte Douglas) is currently priced at $139.

  • Can I find deals for flights from Midway to South Carolina that include hotel bookings?

    Yes. In addition to deals on Midway to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South Carolina.

  • Can I find deals for business class flights from Midway to South Carolina?

    Yes. Cheapflights offers flight deals from Midway to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $163). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $379). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Midway to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Midway to South Carolina

Discover the top 2 airlines that operate flights from Midway to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$214Average$368FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$217Average$364FlexibilityNo cancel feeOn-time63%

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