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South Carolina

$61+ Cheap flights from Midway (MDW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — CHS
mar. 18 — mar. 251
mié. 3/18
mié. 3/25
1 adult, Economy
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Cheap flight deals from Midway to South Carolina

Cheapest flights from Midway to South Carolina
Explore the most affordable flight options available from Midway to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 16, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/137:30 am
MDW
-
CLT
1 stop12h 03m
Multiple Airlines
lun. 5/189:28 pm
CLT
-
MDW
1 stop16h 32m
Multiple Airlines
Deal found 2/12$144
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/127:30 am
MDW
-
CLT
1 stop5h 22m
Multiple Airlines
lun. 3/169:17 pm
CLT
-
MDW
1 stop16h 45m
Multiple Airlines
Deal found 2/12$145
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/56:15 am
MDW
-
CLT
1 stop10h 35m
Multiple Airlines
lun. 3/99:07 pm
CLT
-
MDW
1 stop16h 55m
Multiple Airlines
Deal found 2/12$155
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/156:00 am
MDW
-
GSP
1 stop5h 21m
Delta
sáb. 4/186:51 am
GSP
-
MDW
1 stop4h 05m
Delta
Deal found 2/13$157
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/287:30 am
MDW
-
CLT
1 stop12h 03m
Multiple Airlines
mié. 4/298:05 pm
CLT
-
MDW
1 stop12h 59m
Multiple Airlines
Deal found 2/16$158
This Priceline deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/169:14 am
MDW
-
CLT
1 stop6h 32m
Frontier
lun. 4/204:31 pm
CLT
-
MDW
1 stop6h 50m
Frontier
Deal found 2/16$160
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/127:30 am
MDW
-
CLT
1 stop11h 31m
Multiple Airlines
jue. 3/197:00 am
CLT
-
MDW
1 stop7h 41m
Multiple Airlines
Deal found 2/12$161
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/107:30 am
MDW
-
CLT
1 stop5h 13m
Multiple Airlines
jue. 3/127:00 am
CLT
-
MDW
1 stop7h 41m
Multiple Airlines
Deal found 2/15$166
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/99:51 pm
MDW
-
CLT
1 stop9h 12m
Frontier
vie. 3/139:32 pm
CLT
-
MDW
1 stop17h 09m
Frontier
Deal found 2/12$170
This Super.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/28:15 am
MDW
-
CLT
1 stop12h 32m
Frontier
mié. 3/42:46 pm
CLT
-
MDW
1 stop24h 40m
Frontier
Deal found 2/13$171
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/169:51 pm
MDW
-
CLT
1 stop9h 12m
Multiple Airlines
mié. 3/189:17 pm
CLT
-
MDW
1 stop16h 45m
Multiple Airlines
Deal found 2/13$172
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/177:30 am
MDW
-
CLT
1 stop15h 23m
Multiple Airlines
mar. 3/2411:12 am
CLT
-
MDW
1 stop8h 01m
Multiple Airlines
Deal found 2/15$174

Find flight deals from Midway to South Carolina

Keep the following information in mind while searching for Midway to South Carolina flight deals. Data was last updated febrero 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$144
(Kiwi.com)

One-way from

$61
(Trip.com)

Popular in

December

Cheapest in

August

Average price

$386

Good round-trip deal

$306 or less

Good one-way deal

$313 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
Search Deals
From Chicago Midway to South Carolina
Search Deals
One-way flight from Chicago Midway to South Carolina
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($59 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals
Price to beat on a round-trip flight from Chicago Midway to South Carolina.
Search Deals
Price to beat on a one-way flight from Chicago Midway to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 16, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to South Carolina that are best for you.

Fly from

Midway

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

mié. 4/15

6:00 am-12:21 pm

1 stop5h 21m

Greenville

sáb. 4/18

6:51 am-9:56 am

1 stop4h 05m

$157

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

lun. 4/27

6:55 pm-9:50 pm

Nonstop1h 55m

Charlotte Douglas

jue. 4/30

7:00 pm-8:05 pm

Nonstop2h 05m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

mar. 3/17

11:19 am-12:55 pm

1 stop24h 36m

Charlotte Douglas

mar. 3/24

7:48 pm-6:13 pm

1 stop23h 25m

$192

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

sáb. 3/14

9:35 am-4:19 pm

1 stop5h 44m

Charlotte Douglas

sáb. 3/21

6:00 am-8:53 am

1 stop3h 53m

$192

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

vie. 3/6

6:00 am-11:13 am

1 stop4h 13m

Greenville

mar. 3/10

5:40 am-9:56 am

1 stop5h 16m

$193

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

vie. 5/22

12:51 pm-8:13 pm

1 stop6h 22m

Greenville

lun. 5/25

1:00 pm-4:17 pm

1 stop4h 17m

$193

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

jue. 5/7

6:30 am-1:29 pm

1 stop5h 59m

Charlotte Douglas

dom. 5/10

6:58 am-9:51 am

1 stop3h 53m

$197

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

lun. 4/27

12:52 pm-8:16 pm

1 stop6h 24m

Charlotte Douglas

jue. 4/30

6:00 am-8:47 am

1 stop3h 47m

$197

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

vie. 4/24

5:21 pm-11:53 pm

1 stop5h 32m

Charlotte Douglas

dom. 4/26

6:46 am-9:56 am

1 stop4h 10m

$197

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

mar. 4/21

9:27 am-3:59 pm

1 stop5h 32m

Charlotte Douglas

vie. 4/24

6:00 am-8:47 am

1 stop3h 47m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/12

Showing 1-10 of 60 results
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Best time to book a flight from Midway to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South Carolina

What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDW to SC?

Find hourly flight availability from Midway to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 16, 2026.

A simple way to save on the total cost of your ticket is to fly from Chicago Midway Airport to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 21% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Chicago Midway Airport to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Midway to South Carolina. Price data was last updated on February 7, 2026.

Travelers seeking maximum savings on their Chicago Midway Airport to South Carolina flight should consider departing on Saturday afternoons when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated febrero 16, 2026.
Read through reviews of airlines operating flights from Chicago Midway Airport to South Carolina, such as Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,285 reviews

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,285 reviews
Southwest
8.0
Very good
4,285 reviews

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,204 reviews
Southwest
8.0
Very good
4,285 reviews

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Midway to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to South Carolina?

    Airlines like Delta, Southwest, and Frontier fly from Chicago Midway Airport to South Carolina in about 1h 55m. The time it takes to get you to your destination can typically vary by up to 22h 41m. The distance from Chicago Midway Airport to South Carolina is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Chicago Midway Airport to South Carolina one-way?

    The cheapest airlines for a one-way flight from Chicago Midway Airport to South Carolina are Volaris ($91), Southwest ($121), and Frontier ($144).

  • What are the most popular routes from Chicago Midway Airport to South Carolina?

    While some choose either Chicago Midway - Savannah/Hilton Head or Chicago Midway - Charlotte Douglas, Chicago Midway - Charleston is the most popular route from Chicago Midway Airport to South Carolina.

  • What are the cheapest flights from Chicago Midway Airport to South Carolina?

    On average you can expect to pay $337 for a flight from Chicago Midway Airport to South Carolina. The cheapest flight overall is $122 while the most popular route, (Chicago Midway - Charleston) is currently priced at $162.

  • Can I find deals for flights from Midway to South Carolina that include hotel bookings?

    Yes. In addition to deals on Midway to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South Carolina.

  • Can I find deals for business class flights from Midway to South Carolina?

    Yes. Cheapflights offers flight deals from Midway to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Midway to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Midway to South Carolina

Discover the top 2 airlines that operate flights from Midway to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$118Average$374FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$153Average$346FlexibilityNo cancel feeOn-time63%

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