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South Carolina

$59+ Cheap flights from Midway (MDW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — CHS
Jan 30 — Feb 61
Fri 1/30
Fri 2/6
1 adult, Economy
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Cheap flight deals from Midway to South Carolina

Cheapest flights from Midway to South Carolina
Explore the most affordable flight options available from Midway to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

This Southwest deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:35 amMDW - GSP
1 stop9h 30mSouthwest
Sat 1/38:00 pmGSP - MDW
1 stop4h 20mSouthwest
Deal found 12/29$315
This Southwest deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:35 amMDW - GSP
1 stop9h 30mSouthwest
Thu 1/14:45 pmGSP - MDW
1 stop5h 20mSouthwest
Deal found 12/28$343
This Southwest deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:35 amMDW - GSP
1 stop9h 30mSouthwest
Fri 1/24:20 pmGSP - MDW
1 stop5h 55mSouthwest
Deal found 12/29$362
This Southwest deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:00 amMDW - GSP
1 stop9h 40mSouthwest
Wed 12/314:45 pmGSP - MDW
1 stop5h 20mSouthwest
Deal found 12/29$399
This Southwest deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amMDW - GSP
1 stop6h 25mSouthwest
Wed 12/314:45 pmGSP - MDW
1 stop5h 20mSouthwest
Deal found 12/29$400
This Southwest deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:35 amMDW - GSP
1 stop9h 30mSouthwest
Sun 1/47:40 amGSP - MDW
2 stops6h 15mSouthwest
Deal found 12/29$407
This Southwest deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:00 amMDW - GSP
1 stop9h 40mSouthwest
Thu 1/14:45 pmGSP - MDW
1 stop5h 20mSouthwest
Deal found 12/29$444
This Kiwi.com deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:32 pmMDW - CLT
1 stop27h 37mMultiple Airlines
Mon 1/58:54 amCLT - MDW
2 stops38h 23mMultiple Airlines
Deal found 12/29$473
This Kiwi.com deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:32 pmMDW - CLT
1 stop27h 37mMultiple Airlines
Sat 1/310:22 pmCLT - MDW
1 stop16h 37mMultiple Airlines
Deal found 12/29$599
This Delta deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:29 amMDW - CLT
1 stop4h 32mDelta
Tue 1/611:35 amCLT - MDW
1 stop6h 59mDelta
Deal found 12/30$606
This Kiwi.com deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:32 pmMDW - CLT
1 stop27h 37mMultiple Airlines
Fri 1/22:51 pmCLT - MDW
1 stop8h 07mMultiple Airlines
Deal found 12/29$631
This Southwest deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:25 amMDW - MYR
1 stop5h 40mSouthwest
Mon 1/58:10 pmMYR - MDW
1 stop4h 20mSouthwest
Deal found 12/29$641

Find flight deals from Midway to South Carolina

Keep the following information in mind while searching for Midway to South Carolina flight deals. Data was last updated December 31, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$139
(Southwest)

One-way from

$59
(Southwest)

Popular in

December

Cheapest in

August

Average price

$484

Good round-trip deal

$437 or less

Good one-way deal

$183 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
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From Chicago Midway to South Carolina
Search Deals
One-way flight from Chicago Midway to South Carolina
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Highest demand for flights based on searches. 15% potential increase in price ($61 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Price to beat on a round-trip flight from Chicago Midway to South Carolina.
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Price to beat on a one-way flight from Chicago Midway to South Carolina.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South Carolina that are best for you.

Fly from

Midway

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 2/18

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Mon 2/23

6:20 pm-7:25 pm

Nonstop2h 05m

$158

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sun 1/18

8:19 pm-8:18 am

1 stop10h 59m

Charlotte Douglas

Thu 1/29

9:58 pm-7:52 pm

1 stop22h 54m

$164

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 1/30

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Sun 2/1

5:50 am-6:55 am

Nonstop2h 05m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 2/27

7:35 pm-10:30 pm

Nonstop1h 55m

Charlotte Douglas

Sun 3/1

5:35 am-6:35 am

Nonstop2h 00m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 2/26

9:30 am-12:25 pm

Nonstop1h 55m

Charlotte Douglas

Sun 3/1

5:35 am-6:35 am

Nonstop2h 00m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 2/14

2:30 pm-5:20 pm

Nonstop1h 50m

Charlotte Douglas

Mon 2/16

8:25 pm-9:30 pm

Nonstop2h 05m

$179

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 1/31

4:30 pm-11:54 pm

1 stop6h 24m

Charlotte Douglas

Sun 2/1

5:25 am-9:53 am

1 stop5h 28m

$187

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 1/28

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Wed 2/4

7:45 am-1:55 pm

2 stops7h 10m

$193

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 2/6

9:33 am-4:05 pm

1 stop5h 32m

Charlotte Douglas

Mon 2/9

9:30 am-12:46 pm

1 stop4h 16m

$197

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 1/28

9:33 am-4:05 pm

1 stop5h 32m

Charlotte Douglas

Sat 1/31

6:00 am-8:52 am

1 stop3h 52m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 60 results
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Best time to book a flight from Midway to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South Carolina

What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDW to SC?

Find hourly flight availability from Midway to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 31, 2025.

A simple way to save on the total cost of your ticket is to fly from Chicago Midway Airport to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 18% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Chicago Midway Airport to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Midway to South Carolina. Price data was last updated on August 10, 2025.

Travelers seeking maximum savings on their Chicago Midway Airport to South Carolina flight should consider departing on Saturday afternoons when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 31, 2025.
Read through reviews of airlines operating flights from Chicago Midway Airport to South Carolina, such as Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,251 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,013 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Midway to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to South Carolina?

    Airlines like Southwest, Frontier, and Delta fly from Chicago Midway Airport to South Carolina in about 1h 50m. The time it takes to get you to your destination can typically vary by up to 9h 09m. The distance from Chicago Midway Airport to South Carolina is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Chicago Midway Airport to South Carolina one-way?

    The cheapest airlines for a one-way flight from Chicago Midway Airport to South Carolina are Frontier ($89), Volaris ($107), and Southwest ($114).

  • What are the most popular routes from Chicago Midway Airport to South Carolina?

    While some choose either Chicago Midway - Charlotte Douglas or Chicago Midway - Myrtle Beach Intl, Chicago Midway - Charleston is the most popular route from Chicago Midway Airport to South Carolina.

  • What are the cheapest flights from Chicago Midway Airport to South Carolina?

    On average you can expect to pay $399 for a flight from Chicago Midway Airport to South Carolina. The cheapest flight overall is $313 while the most popular route, (Chicago Midway - Charleston) is currently priced at $246.

  • Can I find deals for flights from Midway to South Carolina that include hotel bookings?

    Yes. In addition to deals on Midway to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South Carolina.

  • Can I find deals for business class flights from Midway to South Carolina?

    Yes. Cheapflights offers flight deals from Midway to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Midway to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Midway to South Carolina

Discover the top 2 airlines that operate flights from Midway to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$214Average$374FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$217Average$355FlexibilityNo cancel feeOn-time63%

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