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South Carolina

$65+ Cheap flights from Midway (MDW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — CHS
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Midway to South Carolina

Cheapest flights from Midway to South Carolina
Explore the most affordable flight options available from Midway to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Southwest deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:30 pmMDW - CLT
Nonstop1h 50mSouthwest
Tue 1/65:50 pmCLT - MDW
Nonstop2h 05mSouthwest
Deal found 12/14$149
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:29 amMDW - CLT
1 stop5h 32mDelta
Wed 12/311:05 pmCLT - MDW
1 stop5h 21mDelta
Deal found 12/14$177
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:29 amMDW - CLT
1 stop5h 32mDelta
Tue 1/61:13 pmCLT - MDW
1 stop4h 16mDelta
Deal found 12/13$178
This Southwest deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 pmMDW - CLT
Nonstop1h 50mSouthwest
Sat 1/101:05 pmCLT - MDW
1 stop5h 15mSouthwest
Deal found 12/14$188
This Southwest deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:30 pmMDW - CLT
Nonstop1h 50mSouthwest
Thu 1/87:45 amCLT - MDW
2 stops7h 10mSouthwest
Deal found 12/14$193
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:29 amMDW - CLT
1 stop5h 32mDelta
Fri 1/96:00 amCLT - MDW
1 stop3h 52mDelta
Deal found 12/13$207
This CheapOair deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:32 pmMDW - CLT
1 stop24h 06mFrontier
Sat 1/108:46 pmCLT - MDW
1 stop27h 13mFrontier
Deal found 12/14$208
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 pmMDW - CLT
Nonstop1h 50mSouthwest
Tue 1/65:50 pmCLT - MDW
Nonstop2h 05mSouthwest
Deal found 12/13$219
This Expedia deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:00 amMDW - CLT
1 stop7h 42mFrontier
Thu 1/88:46 pmCLT - MDW
1 stop27h 23mFrontier
Deal found 12/14$242
This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:10 pmMDW - CHS
1 stop16h 27mMultiple Airlines
Wed 1/72:15 pmCHS - MDW
2 stops22h 16mMultiple Airlines
Deal found 12/12$252
This Delta deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amMDW - GSP
1 stop6h 14mDelta
Tue 12/167:25 amGSP - MDW
1 stop6h 09mDelta
Deal found 12/12$293
This Southwest deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:40 amMDW - CHS
1 stop9h 25mSouthwest
Wed 1/71:45 pmCHS - MDW
1 stop9h 05mSouthwest
Deal found 12/12$299

Find flight deals from Midway to South Carolina

Keep the following information in mind while searching for Midway to South Carolina flight deals. Data was last updated December 15, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$139
(Southwest)

One-way from

$65
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$479

Good round-trip deal

$437 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
Search Deals
From Chicago Midway to South Carolina
Search Deals
One-way flight from Chicago Midway to South Carolina
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($58 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Chicago Midway to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South Carolina that are best for you.

Fly from

Midway

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 12/25

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Tue 1/6

5:50 pm-6:55 pm

Nonstop2h 05m

$149

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 1/15

6:00 pm-8:50 pm

Nonstop1h 50m

Charlotte Douglas

Sun 1/18

8:25 am-2:15 pm

1 stop6h 50m

$168

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 1/13

6:45 am-1:38 pm

1 stop5h 53m

Charlotte Douglas

Sun 1/18

11:35 am-5:34 pm

1 stop6h 59m

$178

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 1/14

9:55 am-5:15 pm

1 stop6h 20m

Charlotte Douglas

Wed 1/21

5:50 pm-6:55 pm

Nonstop2h 05m

$179

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 1/22

5:01 pm-10:38 am

2 stops16h 37m

Charlotte Douglas

Mon 1/26

11:12 am-7:58 pm

1 stop9h 46m

$181

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 1/16

8:04 pm-12:22 pm

1 stop15h 18m

Charlotte Douglas

Tue 1/20

11:35 am-12:05 pm

2 stops25h 30m

$181

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 1/15

6:45 am-1:38 pm

1 stop5h 53m

Charlotte Douglas

Sun 1/18

1:13 pm-4:29 pm

1 stop4h 16m

$187

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 1/14

9:32 am-4:05 pm

1 stop5h 33m

Charlotte Douglas

Mon 1/19

6:59 pm-10:22 pm

1 stop4h 23m

$187

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 1/21

10:46 am-4:02 pm

1 stop4h 16m

Charlotte Douglas

Sun 1/25

12:59 pm-5:55 pm

1 stop5h 56m

$187

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 1/16

12:30 pm-5:40 pm

1 stop4h 10m

Charlotte Douglas

Tue 1/20

5:50 pm-6:55 pm

Nonstop2h 05m

$188

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 60 results
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Best time to book a flight from Midway to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South Carolina

What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $483). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDW to SC?

Find hourly flight availability from Midway to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

A simple way to save on the total cost of your ticket is to fly from Chicago Midway Airport to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 39% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Chicago Midway Airport to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Midway to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Chicago Midway Airport to South Carolina flight should consider departing on Saturday afternoons when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 15, 2025.
Read through reviews of airlines operating flights from Chicago Midway Airport to South Carolina, such as Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Food

7.0

Comfort

8.0

Overall

7.9

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Food

7.0

Comfort

8.0

Overall

7.9

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,250 reviews

Food

7.0

Comfort

8.0

Overall

7.9

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Midway to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to South Carolina?

    Airlines like Southwest and Delta fly from Chicago Midway Airport to South Carolina in about 1h 50m. The time it takes to get you to your destination can typically vary by up to 4h 03m. The distance from Chicago Midway Airport to South Carolina is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Chicago Midway Airport to South Carolina?

    While some choose either Chicago Midway - Charlotte Douglas or Chicago Midway - Myrtle Beach Intl, Chicago Midway - Charleston is the most popular route from Chicago Midway Airport to South Carolina.

  • Can I find deals for flights from Midway to South Carolina that include hotel bookings?

    Yes. In addition to deals on Midway to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South Carolina.

  • Can I find deals for business class flights from Midway to South Carolina?

    Yes. Cheapflights offers flight deals from Midway to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $483). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Midway to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Midway to South Carolina

Discover the top 2 airlines that operate flights from Midway to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$214Average$374FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$217Average$358FlexibilityNo cancel feeOn-time63%

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