HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$68+ Cheap flights from Midway (MDW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — CHS
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Midway to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Midway to South Carolina

Keep the following information in mind while searching for Midway to South Carolina flight deals. Data was last updated January 15, 2026.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$158
(Southwest)

One-way from

$68
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$360

Good round-trip deal

$427 or less

Good one-way deal

$183 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
Search Deals
From Chicago Midway to South Carolina
Search Deals
One-way flight from Chicago Midway to South Carolina
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($69 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Chicago Midway to South Carolina.
Search Deals
Price to beat on a one-way flight from Chicago Midway to South Carolina.
Search Deals

Find flight deals from Midway to South Carolina

Cheapest flights from Midway to South Carolina
Explore the most affordable flight options available from Midway to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This Southwest deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/181:30 pm
MDW
-
CLT
Nonstop1h 50m
Southwest
Sat 2/216:25 pm
CLT
-
MDW
Nonstop2h 05m
Southwest
Deal found 1/13$139
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:15 am
MDW
-
CLT
1 stop10h 35m
Frontier
Sun 2/2210:50 am
CLT
-
MDW
1 stop27h 18m
Frontier
Deal found 1/13$155
This Southwest deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/282:30 pm
MDW
-
CLT
Nonstop1h 50m
Southwest
Sun 3/15:35 am
CLT
-
MDW
Nonstop2h 00m
Southwest
Deal found 1/12$158
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1912:22 pm
MDW
-
CLT
2 stops18h 36m
Multiple Airlines
Sun 2/2210:50 am
CLT
-
MDW
1 stop27h 18m
Multiple Airlines
Deal found 1/13$163
This Southwest deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/142:30 pm
MDW
-
CLT
Nonstop1h 50m
Southwest
Sat 2/146:25 pm
CLT
-
MDW
Nonstop2h 05m
Southwest
Deal found 1/14$169
This Expedia deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/288:00 am
MDW
-
CLT
1 stop6h 53m
Frontier
Sun 3/19:38 am
CLT
-
MDW
1 stop12h 51m
Frontier
Deal found 1/12$170
This Southwest deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/129:30 am
MDW
-
CLT
Nonstop1h 55m
Southwest
Sun 2/156:20 pm
CLT
-
MDW
Nonstop2h 05m
Southwest
Deal found 1/13$177
This Delta deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:00 am
MDW
-
CLT
1 stop6h 38m
Delta
Wed 2/181:11 pm
CLT
-
MDW
1 stop5h 26m
Delta
Deal found 1/13$178
This CheapOair deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/28:15 am
MDW
-
CLT
1 stop10h 28m
Frontier
Thu 3/52:21 pm
CLT
-
MDW
1 stop24h 20m
Frontier
Deal found 1/13$180
This Expedia deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/269:45 am
MDW
-
CLT
1 stop10h 16m
Frontier
Thu 1/299:58 pm
CLT
-
MDW
1 stop22h 54m
Frontier
Deal found 1/13$181
This Southwest deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/101:15 pm
MDW
-
GSP
1 stop5h 35m
Southwest
Tue 2/178:20 am
GSP
-
MDW
1 stop4h 45m
Southwest
Deal found 1/13$215
This Delta deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/512:46 pm
MDW
-
AGS
1 stop5h 06m
Delta
Mon 2/97:33 pm
AGS
-
MDW
1 stop3h 49m
Delta
Deal found 1/13$215

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to South Carolina that are best for you.

Fly from

Midway

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 2/28

2:30 pm-5:20 pm

Nonstop1h 50m

Charlotte Douglas

Sun 3/1

5:35 am-6:35 am

Nonstop2h 00m

$158

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 2/14

2:30 pm-5:20 pm

Nonstop1h 50m

Charlotte Douglas

Sat 2/14

6:25 pm-7:30 pm

Nonstop2h 05m

$169

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 2/12

9:30 am-12:25 pm

Nonstop1h 55m

Charlotte Douglas

Sun 2/15

6:20 pm-7:25 pm

Nonstop2h 05m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 2/7

6:25 am-1:00 pm

1 stop5h 35m

Charlotte Douglas

Sat 2/14

6:00 am-8:54 am

1 stop3h 54m

$178

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 2/28

9:34 am-4:05 pm

1 stop5h 31m

Charlotte Douglas

Sun 3/1

5:25 am-9:54 am

1 stop5h 29m

$187

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 2/14

11:06 am-4:04 pm

1 stop3h 58m

Charlotte Douglas

Mon 2/16

9:30 am-12:46 pm

1 stop4h 16m

$187

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 2/13

7:35 pm-10:30 pm

Nonstop1h 55m

Charlotte Douglas

Mon 2/16

8:25 pm-9:30 pm

Nonstop2h 05m

$188

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 2/14

11:06 am-6:12 pm

1 stop6h 06m

Charlotte Douglas

Tue 2/17

2:26 pm-5:45 pm

1 stop4h 19m

$197

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 2/5

6:00 pm-8:50 pm

Nonstop1h 50m

Charlotte Douglas

Fri 2/13

8:25 pm-9:30 pm

Nonstop2h 05m

$197

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 2/13

6:40 pm-11:49 pm

1 stop4h 09m

Charlotte Douglas

Mon 2/16

9:30 am-12:46 pm

1 stop4h 16m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/13

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Midway to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South Carolina

What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDW to SC?

Find hourly flight availability from Midway to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 15, 2026.

A simple way to save on the total cost of your ticket is to fly from Chicago Midway Airport to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 19% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Chicago Midway Airport to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Midway to South Carolina. Price data was last updated on January 10, 2026.

Travelers seeking maximum savings on their Chicago Midway Airport to South Carolina flight should consider departing on Saturday afternoons when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 15, 2026.
Read through reviews of airlines operating flights from Chicago Midway Airport to South Carolina, such as Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,258 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,258 reviews
Southwest
8.0
Very good
4,258 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,048 reviews
Southwest
8.0
Very good
4,258 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Midway to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to South Carolina?

    Airlines like Southwest and Delta fly from Chicago Midway Airport to South Carolina in about 1h 50m. The time it takes to get you to your destination can typically vary by up to 3h 45m. The distance from Chicago Midway Airport to South Carolina is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Chicago Midway Airport to South Carolina one-way?

    The cheapest airlines for a one-way flight from Chicago Midway Airport to South Carolina are Frontier ($89), Volaris ($112), and Southwest ($114).

  • What are the most popular routes from Chicago Midway Airport to South Carolina?

    While some choose either Chicago Midway - Savannah/Hilton Head or Chicago Midway - Charleston, Chicago Midway - Charlotte Douglas is the most popular route from Chicago Midway Airport to South Carolina.

  • Can I find deals for flights from Midway to South Carolina that include hotel bookings?

    Yes. In addition to deals on Midway to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South Carolina.

  • Can I find deals for business class flights from Midway to South Carolina?

    Yes. Cheapflights offers flight deals from Midway to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Midway to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Las Vegas flights
O'Hare Intl to Sky Harbor Intl flights
O'Hare Intl to Dallas/Fort Worth flights
O'Hare Intl to John F Kennedy Intl flights
O'Hare Intl to Fort Lauderdale flights
O'Hare Intl to Miami flights
O'Hare Intl to Orlando flights
O'Hare Intl to Los Angeles flights
O'Hare Intl to Denver flights
O'Hare Intl to Tampa flights
Midway to Miami flights
O'Hare Intl to San Francisco flights
O'Hare Intl to Fort Myers flights
O'Hare Intl to Seattle flights
Midway to Fort Lauderdale flights
O'Hare Intl to West Palm Beach flights
O'Hare Intl to LaGuardia flights
Midway to Dallas/Fort Worth flights
O'Hare Intl to Newark flights
Midway to Sky Harbor Intl flights
Midway to Las Vegas flights
O'Hare Intl to Atlanta flights
Midway to Orlando flights
O'Hare Intl to New Orleans flights
O'Hare Intl to Sarasota flights
O'Hare Intl to Santa Ana flights
O'Hare Intl to Honolulu flights
O'Hare Intl to Austin flights
O'Hare Intl to Salt Lake City flights
O'Hare Intl to San Diego flights
O'Hare Intl to Baltimore flights
O'Hare Intl to Ontario flights
Midway to Los Angeles flights
O'Hare Intl to Dulles Intl flights
O'Hare Intl to Boston flights
Midway to Newark flights
O'Hare Intl to Nashville flights
O'Hare Intl to Reagan-National flights
Midway to John F Kennedy Intl flights
Midway to Tampa flights
O'Hare Intl to Love Field flights
O'Hare Intl to George Bush Intcntl flights
Midway to Fort Myers flights
O'Hare Intl to Philadelphia flights
Midway to LaGuardia flights
O'Hare Intl to Key West flights
Midway to Atlanta flights
O'Hare Intl to Charleston flights
Midway to West Palm Beach flights
O'Hare Intl to Palm Springs flights

Top 2 airlines flying from Midway to South Carolina

Discover the top 2 airlines that operate flights from Midway to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$118Average$374FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$217Average$348FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.