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South Carolina

$59+ Cheap flights from Midway (MDW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — CHS
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Midway to South Carolina

Cheapest flights from Midway to South Carolina
Explore the most affordable flight options available from Midway to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This Delta deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:29 amMDW - CLT
1 stop4h 32mDelta
Thu 1/16:00 amCLT - MDW
1 stop4h 05mDelta
Deal found 12/22$177
This Delta deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:29 amMDW - CLT
1 stop4h 32mDelta
Tue 1/65:50 pmCLT - MDW
1 stop5h 17mDelta
Deal found 12/22$213
This Southwest deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:25 amMDW - CLT
1 stop5h 15mSouthwest
Thu 1/16:10 amCLT - MDW
Nonstop2h 05mSouthwest
Deal found 12/22$289
This Southwest deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:35 amMDW - CLT
1 stop5h 45mSouthwest
Tue 1/65:50 pmCLT - MDW
Nonstop2h 05mSouthwest
Deal found 12/22$294
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:10 pmMDW - CHS
1 stop16h 27mMultiple Airlines
Wed 1/72:15 pmCHS - MDW
2 stops22h 16mMultiple Airlines
Deal found 12/22$297
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:29 amMDW - CLT
1 stop4h 32mDelta
Sun 1/46:00 amCLT - MDW
1 stop3h 49mDelta
Deal found 12/21$317
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:10 pmMDW - CLT
1 stop26h 14mFrontier
Tue 1/68:46 pmCLT - MDW
2 stops26h 31mFrontier
Deal found 12/22$341
This Southwest deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:25 amMDW - CLT
1 stop5h 15mSouthwest
Sun 1/41:00 pmCLT - MDW
2 stops7h 35mSouthwest
Deal found 12/21$348
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:10 pmMDW - GSP
1 stop18h 43mMultiple Airlines
Mon 1/58:58 pmGSP - MDW
2 stops26h 19mMultiple Airlines
Deal found 12/22$390
This Southwest deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:25 pmMDW - CHS
1 stop5h 15mSouthwest
Wed 1/71:45 pmCHS - MDW
1 stop9h 05mSouthwest
Deal found 12/21$404
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:10 pmMDW - MYR
1 stop26h 27mMultiple Airlines
Sun 1/49:54 amMYR - MDW
2 stops37h 18mMultiple Airlines
Deal found 12/21$412
This Delta deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:29 pmMDW - SAV
1 stop3h 37mDelta
Sun 1/45:30 amSAV - MDW
1 stop4h 35mDelta
Deal found 12/20$415

Find flight deals from Midway to South Carolina

Keep the following information in mind while searching for Midway to South Carolina flight deals. Data was last updated December 23, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$158
(Southwest)

One-way from

$59
(Southwest)

Popular in

December

Cheapest in

August

Average price

$484

Good round-trip deal

$437 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
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From Chicago Midway to South Carolina
Search Deals
One-way flight from Chicago Midway to South Carolina
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($61 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Chicago Midway to South Carolina.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South Carolina that are best for you.

Fly from

Midway

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sun 1/18

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Thu 1/22

5:50 pm-6:55 pm

Nonstop2h 05m

$158

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 1/21

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Wed 1/28

5:50 pm-6:55 pm

Nonstop2h 05m

$169

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 2/18

6:00 am-11:00 am

1 stop4h 00m

Charlotte Douglas

Tue 2/24

5:25 am-9:54 am

1 stop5h 29m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 2/21

11:06 am-6:12 pm

1 stop6h 06m

Charlotte Douglas

Tue 2/24

7:55 am-11:59 am

1 stop5h 04m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 1/23

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Sun 1/25

6:20 pm-7:25 pm

Nonstop2h 05m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 12/31

9:29 am-3:01 pm

1 stop4h 32m

Charlotte Douglas

Thu 1/1

10:08 am-2:44 pm

1 stop5h 36m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 1/21

9:32 am-4:05 pm

1 stop5h 33m

Charlotte Douglas

Wed 1/28

12:59 pm-5:55 pm

1 stop5h 56m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 2/20

6:40 pm-11:49 pm

1 stop4h 09m

Charlotte Douglas

Sat 2/21

6:59 pm-10:31 pm

1 stop4h 32m

$187

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 1/28

9:33 am-4:05 pm

1 stop5h 32m

Charlotte Douglas

Sun 2/1

5:25 am-9:53 am

1 stop5h 28m

$187

ChicagoMyrtle Beach

MDW - MYR

MDWMYR

Chicago Midway

Thu 1/15

6:30 pm-2:42 pm

1 stop19h 12m

Myrtle Beach Intl

Sun 1/18

10:00 am-12:02 am

1 stop15h 02m

$194

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 60 results
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Best time to book a flight from Midway to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South Carolina

What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDW to SC?

Find hourly flight availability from Midway to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

A simple way to save on the total cost of your ticket is to fly from Chicago Midway Airport to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 38% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Chicago Midway Airport to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Midway to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Chicago Midway Airport to South Carolina flight should consider departing on Saturday afternoons when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 23, 2025.
Read through reviews of airlines operating flights from Chicago Midway Airport to South Carolina, such as Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,253 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,253 reviews
Southwest
8.0
Very good
4,253 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,014 reviews
Southwest
8.0
Very good
4,253 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Midway to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to South Carolina?

    Airlines like Southwest and Delta fly from Chicago Midway Airport to South Carolina in about 1h 50m. The time it takes to get you to your destination can typically vary by up to 2h 10m. The distance from Chicago Midway Airport to South Carolina is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Chicago Midway Airport to South Carolina one-way?

    The cheapest airlines for a one-way flight from Chicago Midway Airport to South Carolina are Volaris ($107), Southwest ($114), and Frontier ($215).

  • What are the most popular routes from Chicago Midway Airport to South Carolina?

    While some choose either Chicago Midway - Charlotte Douglas or Chicago Midway - Savannah/Hilton Head, Chicago Midway - Charleston is the most popular route from Chicago Midway Airport to South Carolina.

  • Can I find deals for flights from Midway to South Carolina that include hotel bookings?

    Yes. In addition to deals on Midway to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South Carolina.

  • Can I find deals for business class flights from Midway to South Carolina?

    Yes. Cheapflights offers flight deals from Midway to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $134). Flying from Chicago Midway Airport to South Carolina in December is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Midway to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Midway to South Carolina

Discover the top 2 airlines that operate flights from Midway to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$214Average$374FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$217Average$354FlexibilityNo cancel feeOn-time63%

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