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South Carolina

$66+ Cheap flights from Midway (MDW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — CHS
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheap flight deals from Midway to South Carolina

Keep the following information in mind while searching for Midway to South Carolina flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$139
(Southwest)

One-way from

$66
(Southwest)

Popular in

December

Cheapest in

September

Average price

$228

Good round-trip deal

$301 or less

Good one-way deal

$184 or less
From Chicago Midway to South Carolina
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One-way flight from Chicago Midway to South Carolina
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Highest demand for flights based on searches. 8% potential increase in price ($31 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Chicago Midway to South Carolina.
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Price to beat on a one-way flight from Chicago Midway to South Carolina.
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Find flight deals from Midway to South Carolina

Cheapest flights from Midway to South Carolina
Explore the most affordable flight options available from Midway to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/126:00 pmMDW - CLT
Nonstop1h 50mSouthwest
sáb. 11/151:10 pmCLT - MDW
Nonstop2h 05mSouthwest
Deal found 9/14$139
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/76:30 amMDW - CLT
1 stop6h 30mFrontier
lun. 11/1011:37 amCLT - MDW
1 stop6h 38mFrontier
Deal found 9/14$143
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/31:49 pmMDW - CLT
1 stop6h 36mFrontier
lun. 10/69:11 amCLT - MDW
1 stop10h 32mFrontier
Deal found 9/14$144
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/291:49 pmMDW - CLT
1 stop6h 36mFrontier
vie. 10/39:11 amCLT - MDW
1 stop10h 32mFrontier
Deal found 9/14$145
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/268:35 pmMDW - MYR
Nonstop1h 55mSouthwest
sáb. 11/16:05 amMYR - MDW
Nonstop2h 10mSouthwest
Deal found 9/14$147
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/316:30 amMDW - CLT
1 stop6h 30mFrontier
dom. 11/27:38 pmCLT - MDW
1 stop5h 52mFrontier
Deal found 9/14$150
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/139:15 amMDW - MYR
1 stop5h 54mFrontier
dom. 11/164:59 pmMYR - MDW
1 stop22h 34mFrontier
Deal found 9/13$151
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/1611:49 amMDW - CLT
1 stop5h 44mFrontier
dom. 10/198:59 amCLT - MDW
1 stop9h 28mFrontier
Deal found 9/15$151
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/1410:10 amMDW - MYR
2 stops8h 35mSouthwest
mar. 10/217:10 amMYR - MDW
Nonstop2h 10mSouthwest
Deal found 9/14$152
This Booking.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/1112:30 pmMDW - CLT
1 stop21h 39mFrontier
lun. 10/138:55 amCLT - MDW
1 stop13h 05mFrontier
Deal found 9/14$152
This Booking.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/26:30 amMDW - CLT
1 stop12h 21mFrontier
sáb. 10/42:01 pmCLT - MDW
1 stop20h 17mFrontier
Deal found 9/14$153
This Trip.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/258:15 amMDW - CLT
1 stop4h 42mFrontier
dom. 9/289:11 amCLT - MDW
1 stop10h 32mFrontier
Deal found 9/15$155

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South Carolina that are best for you.

Fly from

Midway

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

jue. 11/13

6:30 am-2:00 pm

1 stop6h 30m

Charlotte Douglas

dom. 11/16

7:38 pm-12:30 am

1 stop5h 52m

$150

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

dom. 10/19

8:25 pm-11:15 pm

Nonstop1h 50m

Charlotte Douglas

mar. 10/21

6:00 am-6:55 am

Nonstop1h 55m

$151

ChicagoMyrtle Beach

MDW - MYR

MDWMYR

Chicago Midway

jue. 11/13

9:15 am-4:09 pm

1 stop5h 54m

Myrtle Beach Intl

dom. 11/16

4:59 pm-2:33 pm

1 stop22h 34m

$151

ChicagoMyrtle Beach

MDW - MYR

MDWMYR

Chicago Midway

mar. 10/14

10:10 am-7:45 pm

2 stops8h 35m

Myrtle Beach Intl

mar. 10/21

7:10 am-8:20 am

Nonstop2h 10m

$152

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

mié. 11/12

6:00 pm-8:50 pm

Nonstop1h 50m

Charlotte Douglas

sáb. 11/15

8:15 am-1:55 pm

1 stop6h 40m

$161

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

sáb. 10/25

6:30 am-7:50 pm

2 stops12h 20m

Charlotte Douglas

mar. 10/28

6:00 am-6:55 am

Nonstop1h 55m

$172

ChicagoMyrtle Beach

MDW - MYR

MDWMYR

Chicago Midway

sáb. 10/25

8:20 am-6:45 pm

2 stops9h 25m

Myrtle Beach Intl

vie. 11/28

8:15 pm-11:30 pm

1 stop4h 15m

$178

ChicagoMyrtle Beach

MDW - MYR

MDWMYR

Chicago Midway

vie. 11/14

9:30 am-7:30 pm

2 stops9h 00m

Myrtle Beach Intl

lun. 11/17

2:55 pm-4:05 pm

Nonstop2h 10m

$184

ChicagoMyrtle Beach

MDW - MYR

MDWMYR

Chicago Midway

mié. 11/12

12:47 pm-5:55 pm

1 stop4h 08m

Myrtle Beach Intl

mié. 11/19

6:50 pm-11:32 pm

1 stop5h 42m

$197

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

mié. 10/8

10:35 am-6:30 pm

1 stop6h 55m

Charlotte Douglas

sáb. 10/11

12:56 pm-6:25 pm

1 stop6h 29m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
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Best time to book a flight from Midway to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South Carolina

What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $217). Flying from Chicago Midway Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDW to SC?

Find hourly flight availability from Midway to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

When flying from Chicago Midway Airport to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated septiembre 15, 2025.
Read through reviews of airlines operating flights from Chicago Midway Airport to South Carolina, such as Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Midway to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to South Carolina?

    Airlines like Frontier, Southwest, and Delta fly from Chicago Midway Airport to South Carolina in about 1h 50m. The time it takes to get you to your destination can typically vary by up to 4h 40m. The distance from Chicago Midway Airport to South Carolina is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Chicago Midway Airport to South Carolina?

    While some choose either Chicago Midway - Charlotte Douglas or Chicago Midway - Savannah/Hilton Head, Chicago Midway - Charleston is the most popular route from Chicago Midway Airport to South Carolina.

  • What are the cheapest flights from Chicago Midway Airport to South Carolina?

    On average you can expect to pay $504 for a flight from Chicago Midway Airport to South Carolina. The cheapest flight overall is $128 while the most popular route, (Chicago Midway - Charleston) is currently priced at $228.

  • Can I find deals for flights from Midway to South Carolina that include hotel bookings?

    Yes. In addition to deals on Midway to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South Carolina.

  • Can I find deals for business class flights from Midway to South Carolina?

    Yes. Cheapflights offers flight deals from Midway to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Chicago Midway Airport to South Carolina (average of $217). Flying from Chicago Midway Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Midway to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Midway to South Carolina

Discover the top 2 airlines that operate flights from Midway to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$214Average$372FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$217Average$365FlexibilityNo cancel feeOn-time63%

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