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$261+ Cheap flights from Medford to Sioux Falls (MFR - FSD)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — FSD
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Medford to Sioux Falls

Cheapest flights from Medford to Sioux Falls
Explore the most affordable flight options available from Medford to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/912:41 pmMFR - FSD
2 stops8h 31mDelta
Wed 12/171:30 pmFSD - MFR
2 stops11h 32mDelta
Deal found 11/11$261
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/93:00 pmMFR - FSD
1 stop6h 32mAmerican Airlines
Wed 12/172:35 pmFSD - MFR
1 stop7h 56mAmerican Airlines
Deal found 11/11$285
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1912:50 pmMFR - FSD
1 stop5h 10mUnited Airlines
Fri 12/268:50 amFSD - MFR
1 stop6h 35mUnited Airlines
Deal found 11/12$384
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/185:20 amMFR - FSD
1 stop6h 41mAmerican Airlines
Sat 11/222:50 pmFSD - MFR
1 stop6h 45mAmerican Airlines
Deal found 11/13$439
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:00 amMFR - FSD
1 stop5h 51mUnited Airlines
Wed 12/178:00 amFSD - MFR
2 stops15h 29mUnited Airlines
Deal found 11/13$453

Cheap flight deals from Medford to Sioux Falls

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Sioux Falls (FSD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$261
(Delta)

Popular in

July

Cheapest in

January

Average price

$552
Provider with most accurate pricing for Medford-Sioux Falls Joe Foss Field flight deals.
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Provider most trusted by Cheapflights users for Medford-Sioux Falls Joe Foss Field flights.
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From Medford to Sioux Falls Joe Foss Field
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($128 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Medford to Sioux Falls that are best for you.

Fly from

Medford

Fly to

Sioux Falls

Route

Depart

Return

Price

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Tue 12/9

12:41 pm-11:12 pm

2 stops8h 31m

Sioux Falls Joe Foss Field

Wed 12/17

1:30 pm-11:02 pm

2 stops11h 32m

$261

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Tue 12/9

3:00 pm-11:32 pm

1 stop6h 32m

Sioux Falls Joe Foss Field

Wed 12/17

2:35 pm-8:31 pm

1 stop7h 56m

$285

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Thu 4/9

12:40 pm-8:35 pm

1 stop5h 55m

Sioux Falls Joe Foss Field

Sat 4/18

5:50 am-11:34 am

2 stops7h 44m

$292

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Fri 2/20

5:25 am-2:28 pm

1 stop7h 03m

Sioux Falls Joe Foss Field

Tue 2/24

2:58 pm-9:20 pm

1 stop8h 22m

$340

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Fri 2/20

6:25 pm-10:46 am

2 stops14h 21m

Sioux Falls Joe Foss Field

Tue 2/24

5:00 pm-9:18 pm

1 stop6h 18m

$380

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Fri 12/19

12:50 pm-8:00 pm

1 stop5h 10m

Sioux Falls Joe Foss Field

Fri 12/26

8:50 am-1:25 pm

1 stop6h 35m

$384

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Tue 12/9

5:00 am-12:51 pm

1 stop5h 51m

Sioux Falls Joe Foss Field

Wed 12/17

8:00 am-9:29 pm

2 stops15h 29m

$453

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Compare providers for flights from Medford to Sioux Falls

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Sioux Falls in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medford-Sioux Falls flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Medford-Sioux Falls flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Medford-Sioux Falls flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medford-Sioux Falls flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Sioux Falls flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Medford to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Sioux Falls

How much does it cost to fly round-trip from Medford to Sioux Falls?

Reviews of airlines servicing Sioux Falls

Get insights into the airlines that provide service to Sioux Falls. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sioux Falls. Reviews last updated November 13, 2025.
See what other customers who have flown with United Airlines from Medford to Sioux Falls have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,017 reviews

Entertainment

7.1

Comfort

7.3

Food

6.6

Crew

8.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,017 reviews
United Airlines
7.4
Good
9,017 reviews

Entertainment

7.1

Comfort

7.3

Food

6.6

Crew

8.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Medford to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Medford to Sioux Falls?

    Departing from Medford to Sioux Falls will take you 5h 55m. Medford and Sioux Falls are separated by a distance of 1317 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Medford to Sioux Falls round-trip?

    Cheapflights users have booked flights from Medford to Sioux Falls round-trip from $298. Users have found that United Airlines is 39% cheaper than the other options available to this destination.

  • Can I find deals for flights from Medford to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Medford to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Sioux Falls.

  • Can I find deals for business class flights from Medford to Sioux Falls?

    Yes. Cheapflights offers flight deals from Medford to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Marshall

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Top airline flying from Medford to Sioux Falls

Discover the top airline that operate flights from Medford to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$298Average$508FlexibilityNo cancel feeOn-time69%

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