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Sioux Falls

$400+ Cheap flights from Medford to Sioux Falls (MFR - FSD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — FSD
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
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Cheap flight deals from Medford to Sioux Falls

Cheapest flights from Medford to Sioux Falls
Explore the most affordable flight options available from Medford to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1211:13 am
MFR
-
FSD
2 stops9h 51m
Delta
Mon 3/164:23 pm
FSD
-
MFR
2 stops9h 24m
Delta
Deal found 2/11$429
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2612:35 pm
MFR
-
FSD
1 stop6h 04m
United Airlines
Mon 3/25:00 pm
FSD
-
MFR
1 stop6h 18m
United Airlines
Deal found 2/11$434
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:36 pm
MFR
-
FSD
2 stops14h 06m
United Airlines
Sun 5/176:00 am
FSD
-
MFR
2 stops7h 47m
United Airlines
Deal found 2/9$452
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:55 am
MFR
-
FSD
2 stops10h 46m
Delta
Mon 3/24:19 pm
FSD
-
MFR
2 stops8h 53m
Delta
Deal found 2/11$459
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:02 am
MFR
-
FSD
1 stop5h 53m
United Airlines
Sun 2/155:00 pm
FSD
-
MFR
1 stop6h 22m
United Airlines
Deal found 2/10$469
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:00 am
MFR
-
FSD
1 stop5h 54m
United Airlines
Mon 3/165:10 pm
FSD
-
MFR
1 stop6h 08m
United Airlines
Deal found 2/11$491
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:34 pm
MFR
-
FSD
2 stops24h 12m
United Airlines
Sat 10/319:14 am
FSD
-
MFR
1 stop5h 55m
United Airlines
Deal found 2/8$533
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2411:30 am
MFR
-
FSD
2 stops9h 25m
Delta
Sat 2/284:19 pm
FSD
-
MFR
2 stops8h 36m
Delta
Deal found 2/9$540
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:00 am
MFR
-
FSD
1 stop13h 04m
United Airlines
Mon 7/279:28 am
FSD
-
MFR
2 stops28h 36m
United Airlines
Deal found 2/11$547

Find flight deals from Medford to Sioux Falls

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Sioux Falls (FSD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$429
(Delta)

One-way from

$400
(United Airlines)

Popular in

July

Cheapest in

April

Average price

$359
Provider with most accurate pricing for Medford-Sioux Falls Joe Foss Field flight deals.
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Provider most trusted by Cheapflights users for Medford-Sioux Falls Joe Foss Field flights.
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From Medford to Sioux Falls Joe Foss Field
Search Deals
One-way flight from Medford to Sioux Falls Joe Foss Field
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($116 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in February 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Medford to Sioux Falls that are best for you.

Fly from

Medford

Fly to

Sioux Falls

Route

Depart

Return

Price

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Thu 3/12

11:13 am-11:04 pm

2 stops9h 51m

Sioux Falls Joe Foss Field

Mon 3/16

4:23 pm-11:47 pm

2 stops9h 24m

$429

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Fri 5/15

6:36 pm-10:42 am

2 stops14h 06m

Sioux Falls Joe Foss Field

Sun 5/17

6:00 am-11:47 am

2 stops7h 47m

$452

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Thu 2/26

12:35 pm-8:39 pm

1 stop6h 04m

Sioux Falls Joe Foss Field

Mon 3/2

11:21 am-9:18 pm

2 stops11h 57m

$453

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Thu 2/26

6:55 am-7:41 pm

2 stops10h 46m

Sioux Falls Joe Foss Field

Mon 3/2

4:19 pm-11:12 pm

2 stops8h 53m

$459

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Thu 3/12

5:00 am-12:54 pm

1 stop5h 54m

Sioux Falls Joe Foss Field

Mon 3/16

5:10 pm-9:18 pm

1 stop6h 08m

$491

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Tue 2/24

11:30 am-10:55 pm

2 stops9h 25m

Sioux Falls Joe Foss Field

Sat 2/28

4:19 pm-10:55 pm

2 stops8h 36m

$540

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Wed 7/22

5:00 am-8:04 pm

1 stop13h 04m

Sioux Falls Joe Foss Field

Mon 7/27

9:28 am-12:04 pm

2 stops28h 36m

$547

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Tue 2/24

5:02 am-12:55 pm

1 stop5h 53m

Sioux Falls Joe Foss Field

Sat 2/28

5:00 pm-9:18 pm

1 stop6h 18m

$569

MedfordSioux Falls

MFR - FSD

MFRFSD

Medford

Sat 2/28

2:00 pm-11:49 pm

2 stops7h 49m

$400

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/9

Compare providers for flights from Medford to Sioux Falls

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Sioux Falls in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medford-Sioux Falls flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Sioux Falls flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Sioux Falls flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medford-Sioux Falls flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Sioux Falls flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Medford to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Sioux Falls

Get insights into the airlines that provide service to Sioux Falls. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sioux Falls. Reviews last updated February 12, 2026.
See what other customers who have flown with United Airlines from Medford to Sioux Falls have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,276 reviews

Comfort

7.3

Food

6.6

Entertainment

7.1

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,276 reviews
United Airlines
7.4
Good
9,276 reviews

Comfort

7.3

Food

6.6

Entertainment

7.1

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Medford to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Medford to Sioux Falls?

    Departing from Medford to Sioux Falls will take you 9h 51m. Medford and Sioux Falls are separated by a distance of 1317 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Medford to Sioux Falls round-trip?

    Cheapflights users have booked flights from Medford to Sioux Falls round-trip from $244. Users have found that United Airlines is 51% cheaper than the other options available to this destination.

  • Can I find deals for flights from Medford to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Medford to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Sioux Falls.

  • Can I find deals for business class flights from Medford to Sioux Falls?

    Yes. Cheapflights offers flight deals from Medford to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Marshall

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Top airline flying from Medford to Sioux Falls

Discover the top airline that operate flights from Medford to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$244Average$525FlexibilityNo cancel feeOn-time69%

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