To save up to 20% on this flight, we recommend booking at least 25 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Dubuque to Sioux Falls from $420 1-2 weeks out and tickets from $449 for flights departing within the next 72 hours.
Flights from Dubuque to Sioux Falls lean towards being more expensive in October. Prices are generally better when you fly from Dubuque to Sioux Falls in August, with the cheapest ticket starting at $133.