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Sao Paulo

$301+ Cheap flights from Missouri to Sao Paulo, Brazil (SAO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAO
Nov 2 — Nov 91
Sun 11/2
Sun 11/9
1 adult, Economy
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Cheap flight deals from Missouri to Sao Paulo

Keep the following information in mind while searching for Missouri to Sao Paulo flight deals. Data was last updated October 3, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$644
(Mytrip)

One-way from

$301
(Kiwi.com)

Popular in

June

Cheapest in

April

Average price

$1,118
Provider with most accurate pricing for Lambert-St Louis-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Sao Paulo (SAO) flights.
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From Missouri to Sao Paulo (SAO)
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One-way flight from Missouri to Sao Paulo (SAO)
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Highest demand for flights based on searches. 3% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Missouri to Sao Paulo

Cheapest flights from Missouri to Sao Paulo
Explore the most affordable flight options available from Missouri to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 3, 2025.

This Mytrip deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:15 pmSTL - VCP
1 stop22h 05mMultiple Airlines
Sat 11/1511:20 pmVCP - STL
1 stop20h 56mMultiple Airlines
Deal found 10/2$644
This Air Canada deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/154:05 pmSTL - GRU
2 stops37h 55mAir Canada
Sat 11/229:45 pmGRU - STL
2 stops20h 44mAir Canada
Deal found 10/1$763
This Air Canada deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:05 pmSTL - GRU
2 stops37h 55mAir Canada
Wed 11/199:45 pmGRU - STL
2 stops20h 44mAir Canada
Deal found 10/2$764
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:15 amSTL - GRU
2 stops17h 25mMultiple Airlines
Mon 12/112:55 pmGRU - STL
1 stop14h 02mMultiple Airlines
Deal found 10/1$871
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2010:20 amMCI - GRU
2 stops16h 55mDelta
Mon 12/111:45 pmGRU - MCI
1 stop20h 45mDelta
Deal found 10/1$945
This Mytrip deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/14:05 pmSTL - GRU
2 stops38h 55mMultiple Airlines
Sat 11/155:25 pmGRU - STL
2 stops26h 51mMultiple Airlines
Deal found 10/2$976
This Gotogate deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/89:15 amSTL - GRU
1 stop22h 00mAir Canada
Thu 10/169:00 pmGRU - STL
2 stops44h 18mAir Canada
Deal found 10/2$999
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/293:25 pmMCI - GRU
1 stop15h 10mDelta
Sat 12/64:30 pmGRU - MCI
2 stops19h 49mDelta
Deal found 10/1$1,025
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/292:49 pmMCI - GRU
1 stop14h 21mAmerican Airlines
Fri 12/512:15 amGRU - MCI
2 stops17h 51mAmerican Airlines
Deal found 10/1$1,030
This KAYAK deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:50 amMCI - GRU
2 stops20h 55mLATAM Airlines
Tue 12/29:15 pmGRU - MCI
1 stop15h 04mLATAM Airlines
Deal found 10/2$1,037
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2710:15 amMCI - GRU
1 stop20h 40mDelta
Tue 12/27:30 amGRU - MCI
2 stops18h 13mDelta
Deal found 10/1$1,045
This Mytrip deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/154:05 pmSTL - GRU
2 stops37h 55mMultiple Airlines
Sat 11/227:30 amGRU - STL
3 stops34h 59mMultiple Airlines
Deal found 9/30$1,064

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 3, 2025.
Use the filters below to find and compare flights from Missouri to Sao Paulo that are best for you.

Fly from

Missouri

Fly to

Sao Paulo

Route

Depart

Return

Price

St. LouisSao Paulo

STL - VCP

STLVCP

Lambert-St Louis

Sat 11/1

7:15 pm-7:20 pm

1 stop22h 05m

Sao Paulo Viracopos

Sat 11/15

11:20 pm-5:16 pm

1 stop20h 56m

$644

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Wed 11/12

4:05 pm-9:00 am

2 stops37h 55m

Sao Paulo Guarulhos Intl

Wed 11/19

9:45 pm-3:29 pm

2 stops20h 44m

$764

St. LouisSao Paulo

STL - VCP

STLVCP

Lambert-St Louis

Thu 1/22

4:05 pm-6:45 pm

2 stops23h 40m

Sao Paulo Viracopos

Sun 2/1

6:05 pm-3:29 pm

2 stops24h 24m

$786

St. LouisSao Paulo

STL - CGH

STLCGH

Lambert-St Louis

Thu 1/22

4:05 pm-7:35 pm

2 stops24h 30m

Sao Paulo Congonhas

Sun 2/1

6:00 pm-3:29 pm

2 stops24h 29m

$787

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Sat 11/15

4:05 pm-9:00 am

2 stops37h 55m

Sao Paulo Guarulhos Intl

Sat 11/22

9:30 pm-3:29 pm

1 stop20h 59m

$838

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Thu 11/20

6:15 am-2:40 am

2 stops17h 25m

Sao Paulo Guarulhos Intl

Mon 12/1

12:55 pm-11:57 pm

1 stop14h 02m

$871

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Mon 1/12

6:09 pm-8:05 am

1 stop34h 56m

Sao Paulo Guarulhos Intl

Wed 3/25

6:00 am-11:37 pm

2 stops19h 37m

$936

Kansas CitySao Paulo

MCI - GRU

MCIGRU

Kansas City

Thu 11/20

10:20 am-6:15 am

2 stops16h 55m

Sao Paulo Guarulhos Intl

Mon 12/1

11:45 pm-5:30 pm

1 stop20h 45m

$945

St. LouisSao Paulo

STL - CGH

STLCGH

Lambert-St Louis

Mon 1/12

3:37 pm-2:25 pm

2 stops19h 48m

Sao Paulo Congonhas

Wed 3/25

6:30 am-10:04 pm

2 stops17h 34m

$947

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Sun 3/29

11:30 am-1:10 pm

2 stops23h 40m

Sao Paulo Guarulhos Intl

Tue 3/31

10:00 pm-2:02 pm

1 stop18h 02m

$958

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/1

Showing 1-10 of 45 results
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Best time to book a flight from Missouri to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Sao Paulo

What is the cheapest month to book a flight from Missouri to Sao Paulo?

Currently, September is the cheapest month in which you can book a flight from Missouri to Sao Paulo (average of $668). Flying from Missouri to Sao Paulo in December is currently the most expensive (average of $1,209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SAO?

Find hourly flight availability from Missouri to Sao Paulo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Sao Paulo as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Sao Paulo?

    For as low as $945, Air Canada can have you in Sao Paulo from Missouri in 16h 55m. The distance from Missouri to Sao Paulo is about 5332 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Sao Paulo one-way?

    One-way options have recently been found by users for as low as $558 on Delta. Other airlines that offer cheap prices include LATAM Airlines from $652 and Air Canada from $731 one-way.

  • What are the most popular routes from Missouri to Sao Paulo?

    While some choose either Lambert-St Louis - Sao Paulo Guarulhos Intl or Lambert-St Louis - Sao Paulo Congonhas, Kansas City - Sao Paulo Guarulhos Intl is the most popular route from Missouri to Sao Paulo.

  • Can I find deals for flights from Missouri to Sao Paulo that include hotel bookings?

    Yes. In addition to deals on Missouri to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Sao Paulo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Sao Paulo.

  • Can I find deals for business class flights from Missouri to Sao Paulo?

    Yes. Cheapflights offers flight deals from Missouri to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Sao Paulo?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Sao Paulo (average of $668). Flying from Missouri to Sao Paulo in December is currently the most expensive (average of $1,209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Sao Paulo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Missouri to Sao Paulo

Discover the top 5 airlines that operate flights from Missouri to Sao Paulo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$756Average$1,170FlexibilityNo cancel feeOn-time81%
Air CanadaCheapest$758Average$766FlexibilityNo cancel feeOn-time67%
American AirlinesCheapest$761Average$1,258FlexibilityNo cancel feeOn-time71%
DeltaCheapest$858Average$1,161FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$864Average$1,187FlexibilityNo cancel feeOn-time69%

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