How long is the flight from Missouri to Sao Paulo?

For as low as $1,060, Air Canada can have you in Sao Paulo from Missouri in 12h 47m. The distance from Missouri to Sao Paulo is about 5332 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Sao Paulo ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit Sao Paulo when rainfall is around 0.8 in.

If weather is an important factor for your trip to Sao Paulo, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

What are the most popular routes from Missouri to Sao Paulo?

While some choose either Lambert-St Louis - Sao Paulo Guarulhos Intl or Lambert-St Louis - Sao Paulo Viracopos, Kansas City - Sao Paulo Guarulhos Intl is the most popular route from Missouri to Sao Paulo.

What are the most popular airlines that fly from Missouri to Sao Paulo?

The most popular airlines flying from Missouri to Sao Paulo are LATAM Airlines, United Airlines and Delta. Something to consider prior to booking your flight.

Can I find deals for flights from Missouri to Sao Paulo that include hotel bookings?

Yes. In addition to deals on Missouri to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Sao Paulo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Sao Paulo.

Can I find deals for business class flights from Missouri to Sao Paulo?

Yes. Cheapflights offers flight deals from Missouri to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$406+ Flights from Missouri to Sao Paulo, Brazil

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Cheap flight deals from Missouri to Sao Paulo

Cheapest flights from Missouri to Sao Paulo
Explore the most affordable flight options available from Missouri to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Mon 12/224:27 pmSTL - GRU

1 stop13h 23mMultiple Airlines

Sun 1/118:15 amGRU - STL

2 stops41h 18mMultiple Airlines

Deal found 12/16

$1,226

Wed 12/1711:36 amMCI - GRU

2 stops18h 19mUnited Airlines

Wed 12/249:45 pmGRU - MCI

1 stop15h 58mUnited Airlines

Deal found 12/16

$1,320

Sat 12/206:15 pmMCI - GRU

3 stops43h 00mMultiple Airlines

Wed 12/318:15 amGRU - MCI

3 stops35h 55mMultiple Airlines

Deal found 12/16

$1,361

Sat 12/205:46 pmMCI - GRU

2 stops24h 04mCopa Airlines

Sun 12/211:40 amGRU - MCI

2 stops21h 02mCopa Airlines

Deal found 12/16

$1,432

Thu 12/189:30 amSTL - GRU

2 stops17h 15mLATAM Airlines

Mon 12/2911:45 pmGRU - STL

1 stop19h 43mLATAM Airlines

Deal found 12/17

$1,456

Wed 12/249:47 amSTL - GRU

2 stops18h 38mLATAM Airlines

Wed 12/3110:40 amGRU - STL

1 stop15h 58mLATAM Airlines

Deal found 12/18

$1,472

Wed 12/244:52 pmSTL - GRU

1 stop14h 03mDelta

Wed 12/319:00 pmGRU - STL

1 stop22h 59mDelta

Deal found 12/17

$1,480

Thu 12/183:10 pmSTL - GRU

2 stops16h 10mUnited Airlines

Mon 12/2910:15 pmGRU - STL

2 stops19h 11mUnited Airlines

Deal found 12/17

$1,485

Sat 12/2011:05 amSTL - GRU

1 stop17h 10mUnited Airlines

Mon 12/2210:25 pmGRU - STL

1 stop14h 43mUnited Airlines

Deal found 12/16

$1,493

Sun 12/215:13 pmSTL - GRU

1 stop33h 27mLATAM Airlines

Tue 12/304:30 pmGRU - STL

2 stops19h 28mLATAM Airlines

Deal found 12/16

$1,528

Sat 12/2012:55 pmSTL - GRU

3 stops22h 15mLATAM Airlines

Mon 12/2210:55 pmGRU - STL

2 stops16h 26mLATAM Airlines

Deal found 12/16

$1,551

Sat 12/205:55 amSTL - GRU

2 stops27h 50mLATAM Airlines

Wed 12/3110:40 amGRU - STL

1 stop15h 58mLATAM Airlines

Deal found 12/16

$1,558

Best flights from Missouri to Sao Paulo
Discover carefully curated flight deals from Missouri to Sao Paulo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Sat 3/74:05 pmSTL - GRU

2 stops37h 55mAir Canada

Wed 3/119:30 pmGRU - STL

1 stop19h 59mAir Canada

Deal found 12/15

$772

Wed 4/16:00 amMCI - GRU

1 stop21h 00mMultiple Airlines

Sun 4/263:40 amGRU - MCI

2 stops22h 19mMultiple Airlines

Deal found 12/16

$808

Sun 3/226:20 pmSTL - GRU

1 stop34h 00mGOL

Sat 4/46:00 amGRU - STL

2 stops17h 51mGOL

Deal found 12/17

$992

Wed 4/16:13 pmMCI - GRU

1 stop12h 47mAmerican Airlines

Thu 4/3010:00 pmGRU - MCI

1 stop22h 07mAmerican Airlines

Deal found 12/16

$1,060

Mon 3/3010:28 amMCI - GRU

2 stops17h 02mLATAM Airlines

Thu 4/308:15 amGRU - MCI

2 stops17h 40mLATAM Airlines

Deal found 12/16

$1,072

Wed 4/16:00 amMCI - GRU

1 stop21h 00mMultiple Airlines

Fri 5/14:10 amGRU - MCI

2 stops21h 49mMultiple Airlines

Deal found 12/16

$821

Mon 3/164:05 pmSTL - GRU

2 stops38h 55mAir Canada

Sun 3/229:15 pmGRU - STL

2 stops44h 14mAir Canada

Deal found 12/17

$845

Thu 1/155:04 pmMCI - GRU

2 stops31h 46mMultiple Airlines

Thu 1/2912:55 pmGRU - MCI

1 stop30h 14mMultiple Airlines

Deal found 12/17

$922

Tue 3/3110:28 amMCI - GRU

2 stops20h 12mLATAM Airlines

Tue 4/2811:45 pmGRU - MCI

2 stops26h 10mLATAM Airlines

Deal found 12/16

$1,072

Fri 3/64:05 pmSTL - GRU

2 stops37h 55mAir Canada

Fri 3/209:15 pmGRU - STL

2 stops20h 14mAir Canada

Deal found 12/17

$1,002

Sun 1/115:11 pmSTL - VCP

2 stops23h 44mMultiple Airlines

Sun 1/2510:10 amVCP - STL

1 stop26h 11mMultiple Airlines

Deal found 12/16

$954

Sat 3/213:22 pmSTL - VCP

2 stops15h 38mAmerican Airlines

Sat 3/287:40 pmVCP - STL

2 stops17h 22mAmerican Airlines

Deal found 12/15

$1,172

Tue 3/315:50 amMCI - GRU

1 stop21h 50mLATAM Airlines

Mon 4/278:35 pmGRU - MCI

1 stop23h 23mLATAM Airlines

Deal found 12/16

$1,072

Sat 2/146:07 pmSTL - VCP

2 stops37h 53mGOL

Sat 2/215:55 pmVCP - STL

2 stops19h 31mGOL

Deal found 12/16

$1,204

Mon 3/309:33 amMCI - GRU

1 stop21h 17mLATAM Airlines

Sun 5/39:30 pmGRU - MCI

2 stops28h 25mLATAM Airlines

Deal found 12/16

$1,072

Sat 2/145:05 amSTL - CGH

2 stops26h 05mGOL

Sat 2/216:35 amCGH - STL

2 stops30h 51mGOL

Deal found 12/16

$1,210

Tue 3/3110:28 amMCI - GRU

2 stops20h 12mLATAM Airlines

Wed 4/2911:45 pmGRU - MCI

2 stops24h 40mLATAM Airlines

Deal found 12/16

$1,072

Fri 3/67:52 amSTL - VCP

1 stop18h 48mMultiple Airlines

Fri 3/2010:10 amVCP - STL

1 stop22h 57mMultiple Airlines

Deal found 12/17

$1,089

Sat 3/213:22 pmSTL - CGH

2 stops19h 13mGOL

Sat 3/286:35 amCGH - STL

2 stops34h 49mGOL

Deal found 12/15

$1,246

Wed 3/259:33 amMCI - GRU

1 stop18h 22mLATAM Airlines

Mon 4/610:50 pmGRU - MCI

1 stop22h 32mLATAM Airlines

Deal found 12/18

$1,072

Mon 3/305:50 amMCI - GRU

2 stops21h 40mLATAM Airlines

Wed 4/2911:45 pmGRU - MCI

2 stops23h 18mLATAM Airlines

Deal found 12/16

$1,072

Mon 3/163:22 pmSTL - CGH

2 stops16h 38mGOL

Sun 3/228:00 pmCGH - STL

2 stops16h 32mGOL

Deal found 12/17

$1,502

Sun 1/115:20 pmSTL - VCP

2 stops47h 20mGOL

Sun 1/258:20 pmVCP - STL

2 stops30h 39mGOL

Deal found 12/16

$1,537

Fri 3/63:31 pmSTL - VCP

2 stops24h 29mGOL

Fri 3/207:40 pmVCP - STL

2 stops16h 56mGOL

Deal found 12/17

$1,561

Fri 3/63:31 pmSTL - CGH

2 stops19h 39mGOL

Fri 3/206:10 pmCGH - STL

2 stops18h 26mGOL

Deal found 12/17

$1,567

Sun 1/113:37 pmSTL - CGH

2 stops19h 48mGOL

Sun 1/255:40 pmCGH - STL

2 stops20h 25mGOL

Deal found 12/16

$1,583

Sat 3/218:53 pmSTL - VCP

1 stop30h 47mMultiple Airlines

Sat 3/2810:45 pmVCP - STL

2 stops18h 26mMultiple Airlines

Deal found 12/15

$2,276

Sat 3/78:17 amSTL - VCP

2 stops18h 23mUnited Airlines

Wed 3/1110:45 pmVCP - STL

2 stops24h 57mUnited Airlines

Deal found 12/15

$7,014

Fri 1/23:30 pmSTL - VCP

2 stops24h 45mGOL

Mon 1/129:50 amVCP - STL

2 stops26h 18mGOL

Deal found 12/16

$2,026

Fri 1/23:30 pmSTL - CGH

2 stops19h 40mGOL

Mon 1/126:00 amCGH - STL

2 stops20h 59mGOL

Deal found 12/16

$2,207

Last-minute flights from Missouri to Sao Paulo
Discover last-minute flight deals from Missouri to Sao Paulo. Data last updated December 18, 2025 and is based on user searches.

Wed 12/1711:36 amMCI - GRU

2 stops18h 19mUnited Airlines

Wed 12/249:45 pmGRU - MCI

1 stop15h 58mUnited Airlines

Deal found 12/16

$1,320

Sat 12/206:15 pmMCI - GRU

3 stops43h 00mMultiple Airlines

Wed 12/318:15 amGRU - MCI

3 stops35h 55mMultiple Airlines

Deal found 12/16

$1,361

Mon 12/224:27 pmSTL - GRU

1 stop13h 23mMultiple Airlines

Sun 1/118:15 amGRU - STL

2 stops41h 18mMultiple Airlines

Deal found 12/16

$1,226

Mon 1/59:55 amSTL - GRU

1 stop18h 20mUnited Airlines

Mon 1/199:45 pmGRU - STL

1 stop19h 45mUnited Airlines

Deal found 12/17

$1,360

Sun 1/115:11 pmSTL - VCP

2 stops23h 44mMultiple Airlines

Sun 1/2510:10 amVCP - STL

1 stop26h 11mMultiple Airlines

Deal found 12/16

$954

Sun 1/116:02 pmSTL - GRU

1 stop33h 18mGOL

Sun 1/259:40 amGRU - STL

2 stops17h 19mGOL

Deal found 12/16

$1,251

Sun 1/113:11 pmSTL - GRU

1 stop13h 04mUnited Airlines

Sun 1/259:30 pmGRU - STL

1 stop16h 11mUnited Airlines

Deal found 12/16

$1,363

Thu 1/155:04 pmMCI - GRU

2 stops31h 46mMultiple Airlines

Thu 1/2912:55 pmGRU - MCI

1 stop30h 14mMultiple Airlines

Deal found 12/17

$922

Thu 1/158:00 amMCI - GRU

2 stops19h 30mCopa Airlines

Wed 1/283:10 amGRU - MCI

2 stops19h 46mCopa Airlines

Deal found 12/17

$1,219

Thu 1/155:50 amMCI - GRU

1 stop20h 50mLATAM Airlines

Thu 1/299:15 pmGRU - MCI

1 stop22h 58mLATAM Airlines

Deal found 12/17

$1,222

Sun 1/185:04 pmMCI - GRU

3 stops29h 31mMultiple Airlines

Wed 1/213:55 amGRU - MCI

3 stops33h 36mMultiple Airlines

Deal found 12/17

$970

Sun 1/186:30 pmMCI - GRU

2 stops36h 50mUnited Airlines

Thu 1/2210:15 pmGRU - MCI

1 stop18h 56mUnited Airlines

Deal found 12/17

$1,345

One-way flights from Missouri to Sao Paulo
Search for one-way flight options from Missouri to Sao Paulo. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Thu 12/2510:42 amSTL - GRU

2 stops19h 08mMultiple Airlines

Deal found 12/16

$406

Wed 12/245:19 pmSTL - GRU

2 stops36h 31mMultiple Airlines

Deal found 12/16

$413

Wed 5/207:30 amSTL - GRU

1 stop23h 35mAir Canada

Deal found 12/17

$465

Fri 2/208:17 pmSTL - GRU

3 stops27h 53mMultiple Airlines

Deal found 12/16

$474

Wed 12/249:50 amSTL - VCP

3 stops30h 30mMultiple Airlines

Deal found 12/16

$533

Thu 12/2510:42 amSTL - VCP

2 stops29h 03mMultiple Airlines

Deal found 12/16

$553

Wed 5/201:30 pmSTL - GRU

2 stops16h 20mDelta

Deal found 12/17

$558

Wed 5/206:05 pmSTL - CGH

2 stops15h 10mAmerican Airlines

Deal found 12/17

$564

Tue 2/106:02 pmSTL - GRU

2 stops25h 53mGOL

Deal found 12/16

$569

Wed 12/244:27 pmSTL - CGH

3 stops36h 08mMultiple Airlines

Deal found 12/16

$596

Fri 2/202:47 pmSTL - VCP

3 stops39h 13mMultiple Airlines

Deal found 12/16

$623

Tue 2/104:05 pmSTL - GRU

1 stop15h 30mAir Canada

Deal found 12/17

$630

Find flight deals from Missouri to Sao Paulo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$697 (Kiwi.com)
One-way from	$406 (Kiwi.com)
Popular in	December
Cheapest in	April
Average price	$1,437

Provider with most accurate pricing for Lambert-St Louis-Sao Paulo (SAO) flight deals.

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Provider most trusted by Cheapflights users for Lambert-St Louis-Sao Paulo (SAO) flights.

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From Missouri to Sao Paulo (SAO)

Search Deals

One-way flight from Missouri to Sao Paulo (SAO)

Search Deals

Highest demand for flights based on searches. 14% potential increase in price ($197 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($28 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Sat 3/7

4:05 pm-9:00 am

2 stops37h 55m

Sao Paulo Guarulhos Intl

Wed 3/11

9:30 pm-3:29 pm

1 stop19h 59m

$772

Kansas CitySao Paulo

MCI - GRU

MCIGRU

Kansas City

Wed 4/1

6:00 am-5:00 am

1 stop21h 00m

Sao Paulo Guarulhos Intl

Sun 4/26

3:40 am-11:59 pm

2 stops22h 19m

$808

Kansas CitySao Paulo

MCI - GRU

MCIGRU

Kansas City

Wed 4/1

6:00 am-5:00 am

1 stop21h 00m

Sao Paulo Guarulhos Intl

Fri 5/1

4:10 am-11:59 pm

2 stops21h 49m

$821

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Mon 3/16

4:05 pm-9:00 am

2 stops38h 55m

Sao Paulo Guarulhos Intl

Sun 3/22

9:15 pm-3:29 pm

2 stops44h 14m

$845

Kansas CitySao Paulo

MCI - GRU

MCIGRU

Kansas City

Thu 1/15

5:04 pm-3:50 am

2 stops31h 46m

Sao Paulo Guarulhos Intl

Thu 1/29

12:55 pm-4:09 pm

1 stop30h 14m

$922

St. LouisSao Paulo

STL - VCP

STLVCP

Lambert-St Louis

Sun 1/11

5:11 pm-7:55 pm

2 stops23h 44m

Sao Paulo Viracopos

Sun 1/25

10:10 am-9:21 am

1 stop26h 11m

$954

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Sun 3/22

6:20 pm-6:20 am

1 stop34h 00m

Sao Paulo Guarulhos Intl

Sat 4/4

6:00 am-9:51 pm

2 stops17h 51m

$992

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Fri 3/6

4:05 pm-9:00 am

2 stops37h 55m

Sao Paulo Guarulhos Intl

Fri 3/20

9:15 pm-3:29 pm

2 stops20h 14m

$1,002

Kansas CitySao Paulo

MCI - GRU

MCIGRU

Kansas City

Wed 4/1

6:13 pm-9:00 am

1 stop12h 47m

Sao Paulo Guarulhos Intl

Thu 4/30

10:00 pm-6:07 pm

1 stop22h 07m

$1,060

Kansas CitySao Paulo

MCI - GRU

MCIGRU

Kansas City

Mon 3/30

10:28 am-5:30 am

2 stops17h 02m

Sao Paulo Guarulhos Intl

Thu 4/30

8:15 am-11:55 pm

2 stops17h 40m

$1,072

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 56 results

...

Best time to book a flight from Missouri to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Sao Paulo

What is the cheapest month to book a flight from Missouri to Sao Paulo?

Currently, July is the cheapest month in which you can book a flight from Missouri to Sao Paulo (average of $465). Flying from Missouri to Sao Paulo in October is currently the most expensive (average of $1,178). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SAO?

A simple way to save on the total cost of your ticket is to fly from Missouri to Sao Paulo at noon. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight in the morning.

Related info for your journey

How long is the flight from Missouri to Sao Paulo?
For as low as $1,060, Air Canada can have you in Sao Paulo from Missouri in 12h 47m. The distance from Missouri to Sao Paulo is about 5332 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the most popular routes from Missouri to Sao Paulo?
While some choose either Lambert-St Louis - Sao Paulo Guarulhos Intl or Lambert-St Louis - Sao Paulo Viracopos, Kansas City - Sao Paulo Guarulhos Intl is the most popular route from Missouri to Sao Paulo.
Can I find deals for flights from Missouri to Sao Paulo that include hotel bookings?
Yes. In addition to deals on Missouri to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Sao Paulo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Sao Paulo.
Can I find deals for business class flights from Missouri to Sao Paulo?
Yes. Cheapflights offers flight deals from Missouri to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Sao Paulo?
Currently, July is the cheapest month in which you can book a flight from Missouri to Sao Paulo (average of $465). Flying from Missouri to Sao Paulo in October is currently the most expensive (average of $1,178). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Missouri to Sao Paulo

Airline	Cheapest	Average	Flexibility	On-time
LATAM Airlines	Cheapest$756	Average$1,277	FlexibilityNo cancel fee	On-time81%
Air Canada	Cheapest$758	Average$767	FlexibilityNo cancel fee	On-time67%
American Airlines	Cheapest$761	Average$1,300	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$796	Average$1,248	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$858	Average$1,164	FlexibilityNo cancel fee	On-timeN/A

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$406+ Cheap flights from Missouri to Sao Paulo, Brazil (SAO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Sao Paulo

Cheapest flights from Missouri to Sao PauloExplore the most affordable flight options available from Missouri to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Missouri to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Missouri to Sao Paulo

Keep the following information in mind while searching for Missouri to Sao Paulo flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Sao Paulo that are best for you.

Best time to book a flight from Missouri to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Sao Paulo

What is the cheapest month to book a flight from Missouri to Sao Paulo?

What is the cheapest time of day to fly from MO to SAO?

Find hourly flight availability from Missouri to Sao Paulo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Missouri to Sao Paulo?

What are the most popular routes from Missouri to Sao Paulo?

Can I find deals for flights from Missouri to Sao Paulo that include hotel bookings?

How can I find direct flights from Missouri to Sao Paulo?

Can I find deals for business class flights from Missouri to Sao Paulo?

What is the cheapest month to book a flight from Missouri to Sao Paulo?

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Alternative routes for Missouri to Sao Paulo

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Missouri to Sao Paulo

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Cheapest flights from Missouri to Sao Paulo
Explore the most affordable flight options available from Missouri to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.