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Sao Paulo

$326+ Cheap flights from Missouri to Sao Paulo, Brazil (SAO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAO
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Missouri to Sao Paulo

Cheapest flights from Missouri to Sao Paulo
Explore the most affordable flight options available from Missouri to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Avianca Connect deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:45 am
MCI
-
GRU
2 stops21h 40m
Multiple Airlines
Mon 4/61:20 am
GRU
-
MCI
2 stops24h 33m
Multiple Airlines
Deal found 1/31$665
This Gurufare deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:06 am
STL
-
GRU
2 stops30h 49m
GOL
Thu 5/149:55 pm
GRU
-
STL
2 stops26h 29m
GOL
Deal found 2/1$760
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:41 am
STL
-
GRU
1 stop18h 09m
Multiple Airlines
Tue 5/121:20 am
GRU
-
STL
2 stops23h 59m
Multiple Airlines
Deal found 2/1$761
This Mytrip deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:45 am
MCI
-
GRU
2 stops32h 30m
Multiple Airlines
Wed 3/259:40 pm
GRU
-
MCI
2 stops28h 13m
Multiple Airlines
Deal found 2/1$766
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:06 am
STL
-
GRU
2 stops33h 54m
GOL
Tue 5/126:00 am
GRU
-
STL
2 stops18h 24m
GOL
Deal found 2/1$770
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
-
GRU
1 stop14h 01m
Multiple Airlines
Tue 3/105:25 pm
GRU
-
STL
2 stops31h 54m
Multiple Airlines
Deal found 2/1$788
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:51 pm
STL
-
GRU
1 stop12h 59m
Multiple Airlines
Wed 3/254:25 am
GRU
-
STL
2 stops32h 06m
Multiple Airlines
Deal found 2/1$790
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:06 am
STL
-
GRU
2 stops24h 09m
GOL
Tue 5/126:00 am
GRU
-
STL
2 stops18h 24m
GOL
Deal found 2/1$798
This FlightHub deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:06 am
STL
-
CGH
2 stops21h 24m
GOL
Tue 5/126:30 am
CGH
-
STL
2 stops17h 54m
GOL
Deal found 2/1$810
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:41 am
STL
-
GRU
1 stop18h 09m
Multiple Airlines
Mon 5/1111:10 am
GRU
-
STL
2 stops38h 09m
Multiple Airlines
Deal found 2/1$816
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:41 am
STL
-
GRU
1 stop18h 09m
Multiple Airlines
Mon 5/111:20 am
GRU
-
STL
2 stops23h 59m
Multiple Airlines
Deal found 2/1$821
This Mytrip deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
MCI
-
GRU
3 stops32h 05m
Multiple Airlines
Sun 5/174:05 am
GRU
-
MCI
3 stops33h 02m
Multiple Airlines
Deal found 2/1$832

Find flight deals from Missouri to Sao Paulo

Keep the following information in mind while searching for Missouri to Sao Paulo flight deals. Data was last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$665
(Avianca Connect)

One-way from

$326
(Kiwi.com)

Popular in

January

Cheapest in

April

Average price

$1,178
Provider with most accurate pricing for Lambert-St Louis-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Sao Paulo (SAO) flights.
Search Deals
From Missouri to Sao Paulo (SAO)
Search Deals
One-way flight from Missouri to Sao Paulo (SAO)
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($174 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Missouri to Sao Paulo that are best for you.

Fly from

Missouri

Fly to

Sao Paulo

Route

Depart

Return

Price

Kansas CitySao Paulo

MCI - GRU

MCIGRU

Kansas City

Wed 4/1

5:45 am-5:25 am

2 stops21h 40m

Sao Paulo Guarulhos Intl

Mon 4/6

1:20 am-11:53 pm

2 stops24h 33m

$665

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Mon 4/13

11:06 am-7:55 pm

2 stops30h 49m

Sao Paulo Guarulhos Intl

Thu 5/14

9:55 pm-10:24 pm

2 stops26h 29m

$760

Kansas CitySao Paulo

MCI - GRU

MCIGRU

Kansas City

Wed 3/18

5:45 am-4:15 pm

2 stops32h 30m

Sao Paulo Guarulhos Intl

Wed 3/25

9:40 pm-11:53 pm

2 stops28h 13m

$766

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Tue 3/3

3:49 pm-8:50 am

1 stop14h 01m

Sao Paulo Guarulhos Intl

Tue 3/10

5:25 pm-11:19 pm

2 stops31h 54m

$788

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Wed 4/15

4:55 pm-4:50 am

1 stop33h 55m

Sao Paulo Guarulhos Intl

Tue 5/12

1:20 am-11:19 pm

2 stops23h 59m

$788

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Wed 3/18

4:51 pm-7:50 am

1 stop12h 59m

Sao Paulo Guarulhos Intl

Wed 3/25

4:25 am-10:31 am

2 stops32h 06m

$790

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Wed 4/15

11:06 am-1:15 pm

2 stops24h 09m

Sao Paulo Guarulhos Intl

Tue 5/12

6:00 am-10:24 pm

2 stops18h 24m

$798

St. LouisSao Paulo

STL - CGH

STLCGH

Lambert-St Louis

Mon 4/13

11:06 am-10:30 am

2 stops21h 24m

Sao Paulo Congonhas

Tue 5/12

6:30 am-10:24 pm

2 stops17h 54m

$810

Kansas CitySao Paulo

MCI - GRU

MCIGRU

Kansas City

Fri 5/8

6:00 am-4:05 pm

3 stops32h 05m

Sao Paulo Guarulhos Intl

Sun 5/17

4:05 am-11:07 am

3 stops33h 02m

$832

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Tue 4/14

11:06 am-10:00 pm

2 stops32h 54m

Sao Paulo Guarulhos Intl

Wed 5/13

4:45 pm-10:24 pm

2 stops31h 39m

$836

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

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Best time to book a flight from Missouri to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Sao Paulo

What is the cheapest month to book a flight from Missouri to Sao Paulo?

Currently, July is the cheapest month in which you can book a flight from Missouri to Sao Paulo (average of $465). Flying from Missouri to Sao Paulo in January is currently the most expensive (average of $1,300). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Sao Paulo?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Sao Paulo?

    For as low as $760, GOL can have you in Sao Paulo from Missouri in 30h 49m. The distance from Missouri to Sao Paulo is about 5146 mi.

  • What are the most popular routes from Missouri to Sao Paulo?

    While some choose either Lambert-St Louis - Sao Paulo Guarulhos Intl or Lambert-St Louis - Sao Paulo Congonhas, Kansas City - Sao Paulo Guarulhos Intl is the most popular route from Missouri to Sao Paulo.

  • Can I find deals for flights from Missouri to Sao Paulo that include hotel bookings?

    Yes. In addition to deals on Missouri to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Sao Paulo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Sao Paulo.

  • Can I find deals for business class flights from Missouri to Sao Paulo?

    Yes. Cheapflights offers flight deals from Missouri to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Sao Paulo?

    Currently, July is the cheapest month in which you can book a flight from Missouri to Sao Paulo (average of $465). Flying from Missouri to Sao Paulo in January is currently the most expensive (average of $1,300). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Sao Paulo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Missouri to Sao Paulo

Discover the top 5 airlines that operate flights from Missouri to Sao Paulo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
Air CanadaCheapest$758Average$767FlexibilityNo cancel feeOn-time67%
United AirlinesCheapest$864Average$1,088FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$1,044Average$1,397FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$1,064Average$1,348FlexibilityNo cancel feeOn-time71%
DeltaCheapest$1,068Average$1,158FlexibilityNo cancel feeOn-timeN/A

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