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Santo Domingo

$215+ Cheap flights from Mississippi to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SDQ
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Mississippi to Santo Domingo

Keep the following information in mind while searching for Mississippi to Santo Domingo flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$399
(Kiwi.com)

One-way from

$215
(Kiwi.com)
Provider with most accurate pricing for Jackson-Evers Intl-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Santo Domingo Las Americas flights.
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From Mississippi to Santo Domingo Las Americas
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One-way flight from Mississippi to Santo Domingo Las Americas
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Find flight deals from Mississippi to Santo Domingo

Cheapest flights from Mississippi to Santo Domingo
Explore the most affordable flight options available from Mississippi to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/116:34 pmMEM - SDQ
1 stop20h 11mMultiple Airlines
Fri 5/164:50 pmSDQ - MEM
1 stop15h 42mMultiple Airlines
Deal found 4/30$399
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/175:35 amMEM - SDQ
1 stop8h 45mAmerican Airlines
Fri 7/42:35 pmSDQ - MEM
1 stop10h 33mAmerican Airlines
Deal found 4/29$465
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1711:00 amMEM - SDQ
2 stops12h 37mDelta
Fri 7/46:00 amSDQ - MEM
2 stops15h 59mDelta
Deal found 4/30$479
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/210:12 amJAN - SDQ
2 stops11h 28mAmerican Airlines
Thu 6/1210:13 amSDQ - JAN
2 stops14h 40mAmerican Airlines
Deal found 4/30$514
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/24:08 pmMEM - SDQ
1 stop8h 42mUnited Airlines
Thu 6/123:20 pmSDQ - MEM
1 stop9h 22mUnited Airlines
Deal found 4/30$555
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/211:07 amJAN - SDQ
2 stops12h 12mDelta
Thu 6/122:46 pmSDQ - JAN
1 stop9h 48mDelta
Deal found 4/30$600
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1312:04 pmBTR - SDQ
2 stops12h 46mUnited Airlines
Thu 5/151:10 pmSDQ - BTR
2 stops33h 38mUnited Airlines
Deal found 4/29$731
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/136:00 amBTR - SDQ
1 stop6h 16mDelta
Thu 5/152:41 pmSDQ - BTR
1 stop8h 28mDelta
Deal found 4/29$1,699

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Mississippi to Santo Domingo that are best for you.

Fly from

Mississippi

Fly to

Santo Domingo

Route

Depart

Return

Price

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Sun 5/11

6:34 pm-3:45 pm

1 stop20h 11m

Santo Domingo Las Americas

Fri 5/16

4:50 pm-7:32 am

1 stop15h 42m

$399

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Tue 6/17

5:35 am-3:20 pm

1 stop8h 45m

Santo Domingo Las Americas

Fri 7/4

2:35 pm-12:08 am

1 stop10h 33m

$465

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Tue 6/17

11:00 am-12:37 am

2 stops12h 37m

Santo Domingo Las Americas

Fri 7/4

6:00 am-8:59 pm

2 stops15h 59m

$479

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

Mon 6/2

10:12 am-10:40 pm

2 stops11h 28m

Santo Domingo Las Americas

Thu 6/12

10:13 am-11:53 pm

2 stops14h 40m

$514

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Mon 6/2

4:08 pm-1:50 am

1 stop8h 42m

Santo Domingo Las Americas

Thu 6/12

3:20 pm-11:42 pm

1 stop9h 22m

$555

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

Mon 6/2

11:07 am-12:19 am

2 stops12h 12m

Santo Domingo Las Americas

Thu 6/12

2:46 pm-11:34 pm

1 stop9h 48m

$600

Baton RougeSanto Domingo

BTR - SDQ

BTRSDQ

Baton Rouge Ryan

Tue 5/13

12:04 pm-1:50 am

2 stops12h 46m

Santo Domingo Las Americas

Thu 5/15

1:10 pm-9:48 pm

2 stops33h 38m

$731

Baton RougeSanto Domingo

BTR - SDQ

BTRSDQ

Baton Rouge Ryan

Tue 5/13

6:00 am-1:16 pm

1 stop6h 16m

Santo Domingo Las Americas

Thu 5/15

2:41 pm-10:09 pm

1 stop8h 28m

$1,699

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Tue 6/10

5:14 pm-3:00 pm

2 stops20h 46m

$215

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Tue 6/10

5:14 pm-2:45 am

3 stops32h 31m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 11 results
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Best time to book a flight from Mississippi to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Santo Domingo

Rainfall in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

Temperature in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated May 1, 2025.
See what other customers who have flown with Delta, United Airlines and American Airlines from Mississippi to Santo Domingo have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Spirit Airlines
6.3
Okay
7,963 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santo Domingo from Mississippi?

    Most people fly into Santo Domingo Las Americas (SDQ) if they book a flight to Santo Domingo from Mississippi. Las Americas is conveniently located just 17.5 mi from Santo Domingo’s city center.

  • What are the most popular routes from Mississippi to Santo Domingo?

    The most popular route from Mississippi to Santo Domingo is Memphis - Santo Domingo Las Americas. You may also consider Jackson-Evers Intl - Santo Domingo Las Americas or Baton Rouge Ryan - Santo Domingo Las Americas.

  • Can I find deals for flights from Mississippi to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Mississippi to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Santo Domingo.

  • Can I find deals for business class flights from Mississippi to Santo Domingo?

    Yes. Cheapflights offers flight deals from Mississippi to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Mississippi to Santo Domingo (average of $362). Flying from Mississippi to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Mississippi to Santo Domingo

Discover the top airline that operate flights from Mississippi to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$454Average$454FlexibilityNo cancel feeOn-time71%

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