How long is the flight from Mississippi to Santo Domingo?

Delta, Spirit Airlines, and United Airlines can get you from Mississippi to Santo Domingo in just under 7h 20m. Your travel time can differ by up to 10h 30m. There are 1692 mi between Mississippi and Santo Domingo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What are the most popular routes from Mississippi to Santo Domingo?

The most popular route from Mississippi to Santo Domingo is Memphis - Santo Domingo Las Americas. You may also consider Jackson-Evers Intl - Santo Domingo Las Americas or Baton Rouge Ryan - Santo Domingo Las Americas.

What is the cheapest time of day to fly from MS to SDQ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Santo Domingo as you normally would.

What airport do you fly into for flights to Santo Domingo from Mississippi?

Most people fly into Santo Domingo Las Americas (SDQ) if they book a flight to Santo Domingo from Mississippi. Las Americas is conveniently located just 17.5 mi from Santo Domingo’s city center.

Can I find deals for flights from Mississippi to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Mississippi to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mississippi to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Santo Domingo.

Can I find deals for business class flights from Mississippi to Santo Domingo?

Yes. Cheapflights offers flight deals from Mississippi to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$465+ Cheap Flights from Mississippi to Santo Domingo

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Cheap flight deals from Mississippi to Santo Domingo

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From Mississippi to Santo Domingo Las Americas

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Find flight deals from Mississippi to Santo Domingo

Cheapest flights from Mississippi to Santo Domingo
Explore the most affordable flight options available from Mississippi to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 10, 2025.

mié. 10/227:00 amMEM - SDQ

2 stops30h 48mMultiple Airlines

sáb. 10/253:59 pmSDQ - MEM

1 stop16h 28mMultiple Airlines

Deal found 10/9

$465

jue. 11/67:43 pmJAN - SDQ

2 stops18h 02mAmerican Airlines

jue. 11/131:19 pmSDQ - JAN

2 stops10h 37mAmerican Airlines

Deal found 10/9

$507

mar. 10/145:35 pmMEM - SDQ

1 stop17h 49mDelta

mar. 10/216:05 amSDQ - MEM

1 stop17h 05mDelta

Deal found 10/8

$515

lun. 12/153:16 pmMEM - SDQ

2 stops28h 24mMultiple Airlines

lun. 12/226:55 pmSDQ - MEM

1 stop26h 47mMultiple Airlines

Deal found 10/7

$519

dom. 10/129:36 amMEM - SDQ

2 stops13h 51mDelta

jue. 10/231:49 pmSDQ - MEM

2 stops21h 04mDelta

Deal found 10/8

$520

mié. 12/314:19 pmMEM - SDQ

1 stop7h 20mSpirit Airlines

jue. 1/88:01 amSDQ - MEM

1 stop9h 13mSpirit Airlines

Deal found 10/7

$524

jue. 10/166:19 amMEM - SDQ

1 stop11h 05mDelta

vie. 10/246:05 amSDQ - MEM

1 stop11h 31mDelta

Deal found 10/8

$525

sáb. 10/116:56 pmMEM - SDQ

2 stops13h 29mAmerican Airlines

sáb. 10/1810:25 amSDQ - MEM

2 stops14h 34mAmerican Airlines

Deal found 10/9

$530

vie. 10/247:00 amJAN - SDQ

2 stops17h 50mUnited Airlines

mar. 10/285:00 amSDQ - JAN

2 stops17h 59mUnited Airlines

Deal found 10/9

$530

jue. 10/166:19 amMEM - SDQ

1 stop11h 05mDelta

sáb. 10/256:05 amSDQ - MEM

1 stop10h 33mDelta

Deal found 10/8

$535

vie. 10/317:05 amMEM - SDQ

1 stop5h 36mDelta

dom. 11/27:05 amSDQ - MEM

1 stop11h 31mDelta

Deal found 10/9

$536

vie. 10/316:00 amMEM - SDQ

2 stops13h 30mAmerican Airlines

dom. 11/26:24 pmSDQ - MEM

2 stops17h 20mAmerican Airlines

Deal found 10/9

$546

Best flights from Mississippi to Santo Domingo
Discover carefully curated flight deals from Mississippi to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated octubre 10, 2025.

mié. 10/227:00 amMEM - SDQ

2 stops30h 48mMultiple Airlines

sáb. 10/253:59 pmSDQ - MEM

1 stop16h 28mMultiple Airlines

Deal found 10/9

$465

dom. 3/17:20 pmMEM - SDQ

2 stops16h 10mDelta

jue. 3/53:40 pmSDQ - MEM

1 stop6h 50mDelta

Deal found 10/7

$522

mié. 12/314:19 pmMEM - SDQ

1 stop7h 20mSpirit Airlines

jue. 1/88:01 amSDQ - MEM

1 stop9h 13mSpirit Airlines

Deal found 10/7

$524

vie. 10/247:00 amJAN - SDQ

2 stops17h 50mUnited Airlines

mar. 10/285:00 amSDQ - JAN

2 stops17h 59mUnited Airlines

Deal found 10/9

$530

vie. 1/94:19 pmMEM - SDQ

1 stop7h 20mMultiple Airlines

lun. 1/197:05 pmSDQ - MEM

2 stops46h 09mMultiple Airlines

Deal found 10/7

$520

lun. 3/235:45 amJAN - SDQ

1 stop6h 30mDelta

jue. 3/267:00 pmSDQ - JAN

2 stops17h 27mDelta

Deal found 10/7

$522

jue. 2/194:19 pmMEM - SDQ

1 stop7h 20mSpirit Airlines

dom. 2/226:55 pmSDQ - MEM

2 stops22h 19mSpirit Airlines

Deal found 10/9

$533

mié. 10/226:00 amMEM - SDQ

1 stop6h 41mDelta

sáb. 10/256:05 amSDQ - MEM

1 stop11h 31mDelta

Deal found 10/9

$525

mar. 12/308:27 pmMEM - SDQ

1 stop19h 23mMultiple Airlines

sáb. 1/106:55 pmSDQ - MEM

1 stop16h 55mMultiple Airlines

Deal found 10/7

$563

lun. 12/154:19 pmMEM - SDQ

1 stop7h 20mSpirit Airlines

lun. 12/228:01 amSDQ - MEM

1 stop9h 13mSpirit Airlines

Deal found 10/7

$564

dom. 12/217:50 pmJAN - SDQ

2 stops17h 59mAmerican Airlines

dom. 1/46:51 pmSDQ - JAN

2 stops19h 14mAmerican Airlines

Deal found 10/9

$1,287

vie. 10/317:05 amMEM - SDQ

1 stop5h 36mDelta

dom. 11/27:05 amSDQ - MEM

1 stop11h 31mDelta

Deal found 10/9

$536

mar. 3/106:00 amBTR - SDQ

1 stop6h 15mDelta

mié. 3/112:40 pmSDQ - BTR

1 stop8h 24mDelta

Deal found 10/7

$558

jue. 11/65:32 amJAN - SDQ

1 stop7h 09mDelta

jue. 11/133:57 pmSDQ - JAN

1 stop6h 37mDelta

Deal found 10/9

$829

vie. 10/245:32 amJAN - SDQ

1 stop7h 09mDelta

mar. 10/282:56 pmSDQ - JAN

1 stop8h 54mDelta

Deal found 10/9

$1,002

Last-minute flights from Mississippi to Santo Domingo
Discover last-minute flight deals from Mississippi to Santo Domingo. Data last updated octubre 10, 2025 and is based on user searches.

sáb. 10/116:56 pmMEM - SDQ

2 stops13h 29mAmerican Airlines

sáb. 10/1810:25 amSDQ - MEM

2 stops14h 34mAmerican Airlines

Deal found 10/9

$530

dom. 10/128:05 amMEM - SDQ

2 stops15h 22mDelta

mar. 10/216:05 amSDQ - MEM

1 stop10h 33mDelta

Deal found 10/8

$520

mar. 10/147:05 amMEM - SDQ

1 stop5h 36mDelta

mié. 10/222:56 pmSDQ - MEM

1 stop9h 00mDelta

Deal found 10/8

$515

jue. 10/166:19 amMEM - SDQ

1 stop11h 05mDelta

vie. 10/246:05 amSDQ - MEM

1 stop11h 31mDelta

Deal found 10/8

$525

jue. 10/166:19 amMEM - SDQ

1 stop11h 05mDelta

sáb. 10/256:05 amSDQ - MEM

1 stop10h 33mDelta

Deal found 10/8

$535

vie. 10/1712:24 pmBTR - SDQ

2 stops20h 01mAmerican Airlines

vie. 10/244:20 pmSDQ - BTR

2 stops19h 27mAmerican Airlines

Deal found 10/9

$575

sáb. 10/182:57 pmMEM - SDQ

2 stops22h 51mSpirit Airlines

lun. 10/205:12 pmSDQ - MEM

2 stops27h 33mSpirit Airlines

Deal found 10/8

$556

mié. 10/227:00 amMEM - SDQ

2 stops30h 48mMultiple Airlines

sáb. 10/253:59 pmSDQ - MEM

1 stop16h 28mMultiple Airlines

Deal found 10/9

$465

vie. 10/247:00 amJAN - SDQ

2 stops17h 50mUnited Airlines

mar. 10/285:00 amSDQ - JAN

2 stops17h 59mUnited Airlines

Deal found 10/9

$530

vie. 10/317:05 amMEM - SDQ

1 stop5h 36mDelta

dom. 11/27:05 amSDQ - MEM

1 stop11h 31mDelta

Deal found 10/9

$536

vie. 10/316:00 amMEM - SDQ

2 stops13h 30mAmerican Airlines

dom. 11/26:24 pmSDQ - MEM

2 stops17h 20mAmerican Airlines

Deal found 10/9

$546

jue. 11/67:43 pmJAN - SDQ

2 stops18h 02mAmerican Airlines

jue. 11/131:19 pmSDQ - JAN

2 stops10h 37mAmerican Airlines

Deal found 10/9

$507

One-way flights from Mississippi to Santo Domingo
Search for one-way flight options from Mississippi to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated octubre 10, 2025.

jue. 12/185:10 amBTR - SDQ

2 stops16h 36mUnited Airlines

Deal found 10/8

$980

sáb. 12/209:35 amBTR - SDQ

2 stops12h 11mUnited Airlines

Deal found 10/8

$1,997

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

mié. 10/22

7:00 am-2:48 pm

2 stops30h 48m

Santo Domingo Las Americas

sáb. 10/25

3:59 pm-7:27 am

1 stop16h 28m

$465

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

vie. 1/9

4:19 pm-1:39 am

1 stop7h 20m

Santo Domingo Las Americas

lun. 1/19

7:05 pm-3:14 pm

2 stops46h 09m

$520

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

dom. 3/1

7:20 pm-1:30 pm

2 stops16h 10m

Santo Domingo Las Americas

jue. 3/5

3:40 pm-8:30 pm

1 stop6h 50m

$522

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

lun. 3/23

5:45 am-1:15 pm

1 stop6h 30m

Santo Domingo Las Americas

jue. 3/26

7:00 pm-11:27 am

2 stops17h 27m

$522

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

mié. 12/31

4:19 pm-1:39 am

1 stop7h 20m

Santo Domingo Las Americas

jue. 1/8

8:01 am-3:14 pm

1 stop9h 13m

$524

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

mié. 10/22

6:00 am-1:41 pm

1 stop6h 41m

Santo Domingo Las Americas

sáb. 10/25

6:05 am-4:36 pm

1 stop11h 31m

$525

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

vie. 10/24

7:00 am-1:50 am

2 stops17h 50m

Santo Domingo Las Americas

mar. 10/28

5:00 am-9:59 pm

2 stops17h 59m

$530

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

jue. 2/19

4:19 pm-1:39 am

1 stop7h 20m

Santo Domingo Las Americas

dom. 2/22

6:55 pm-3:14 pm

2 stops22h 19m

$533

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

vie. 10/31

7:05 am-1:41 pm

1 stop5h 36m

Santo Domingo Las Americas

dom. 11/2

7:05 am-4:36 pm

1 stop11h 31m

$536

Baton RougeSanto Domingo

BTR - SDQ

BTRSDQ

Baton Rouge Ryan

mar. 3/10

6:00 am-1:15 pm

1 stop6h 15m

Santo Domingo Las Americas

mié. 3/11

2:40 pm-10:04 pm

1 stop8h 24m

$558

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/8

Showing 1-10 of 17 results

Best time to book a flight from Mississippi to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Mississippi with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Santo Domingo

No data available for this route at this time. Please check back soon.

Related info for your journey

What airport do you fly into for flights to Santo Domingo from Mississippi?
Most people fly into Santo Domingo Las Americas (SDQ) if they book a flight to Santo Domingo from Mississippi. Las Americas is conveniently located just 17.5 mi from Santo Domingo’s city center.
How long is the flight from Mississippi to Santo Domingo?
Delta, Spirit Airlines, and United Airlines can get you from Mississippi to Santo Domingo in just under 7h 20m. Your travel time can differ by up to 10h 30m. There are 1692 mi between Mississippi and Santo Domingo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the most popular routes from Mississippi to Santo Domingo?
The most popular route from Mississippi to Santo Domingo is Memphis - Santo Domingo Las Americas. You may also consider Jackson-Evers Intl - Santo Domingo Las Americas or Baton Rouge Ryan - Santo Domingo Las Americas.
Can I find deals for flights from Mississippi to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Mississippi to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mississippi to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Santo Domingo.
Can I find deals for business class flights from Mississippi to Santo Domingo?
Yes. Cheapflights offers flight deals from Mississippi to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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$465+ Cheap flights from Mississippi to Santo Domingo (SDQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Mississippi to Santo Domingo with Cheapflights

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Cheap flight deals from Mississippi to Santo Domingo

Keep the following information in mind while searching for Mississippi to Santo Domingo flight deals. Data was last updated octubre 10, 2025.

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Find flight deals from Mississippi to Santo Domingo

Cheapest flights from Mississippi to Santo DomingoExplore the most affordable flight options available from Mississippi to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 10, 2025.

Explore the most affordable flight options available from Mississippi to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 10, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to Santo Domingo that are best for you.

Best time to book a flight from Mississippi to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Mississippi with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Santo Domingo

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santo Domingo from Mississippi?

How long is the flight from Mississippi to Santo Domingo?

What are the most popular routes from Mississippi to Santo Domingo?

Can I find deals for flights from Mississippi to Santo Domingo that include hotel bookings?

How can I find direct flights from Mississippi to Santo Domingo?

Can I find deals for business class flights from Mississippi to Santo Domingo?

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Cheapest flights from Mississippi to Santo Domingo
Explore the most affordable flight options available from Mississippi to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 10, 2025.