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Santo Domingo

$378+ Cheap flights from Louisville (SDF) to Santo Domingo (SDQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — SDQ
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Find cheap flights from Louisville to Santo Domingo with Cheapflights

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Cheap flight deals from Louisville to Santo Domingo

Cheapest flights from Louisville to Santo Domingo
Explore the most affordable flight options available from Louisville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/53:33 pm
SDF
-
SDQ
1 stop21h 47m
Spirit Airlines
Wed 3/182:59 am
SDQ
-
SDF
1 stop11h 34m
Spirit Airlines
Deal found 1/27$378
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/201:19 pm
SDF
-
SDQ
2 stops24h 01m
Spirit Airlines
Wed 2/253:32 pm
SDQ
-
SDF
1 stop24h 06m
Spirit Airlines
Deal found 1/26$399
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/53:33 pm
SDF
-
SDQ
2 stops18h 08m
Multiple Airlines
Wed 3/182:59 am
SDQ
-
SDF
1 stop11h 34m
Multiple Airlines
Deal found 1/27$434
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/209:30 am
SDF
-
SDQ
1 stop27h 50m
Multiple Airlines
Wed 2/253:32 pm
SDQ
-
SDF
1 stop24h 06m
Multiple Airlines
Deal found 1/26$453
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/111:19 pm
SDF
-
SDQ
2 stops16h 06m
Multiple Airlines
Sun 3/152:30 pm
SDQ
-
SDF
1 stop29h 58m
Multiple Airlines
Deal found 1/29$493
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:33 pm
SDF
-
SDQ
1 stop10h 05m
Spirit Airlines
Mon 4/62:30 pm
SDQ
-
SDF
1 stop21h 49m
Spirit Airlines
Deal found 1/28$500
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:10 pm
SDF
-
SDQ
1 stop17h 22m
Multiple Airlines
Tue 6/163:37 pm
SDQ
-
SDF
1 stop19h 53m
Multiple Airlines
Deal found 1/28$510
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:05 am
SDF
-
SDQ
1 stop17h 50m
Delta
Thu 6/187:25 pm
SDQ
-
SDF
1 stop15h 30m
Delta
Deal found 1/28$539
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:35 am
SDF
-
SDQ
1 stop12h 17m
Delta
Tue 4/72:37 pm
SDQ
-
SDF
1 stop6h 39m
Delta
Deal found 1/27$549
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 am
SDF
-
SDQ
2 stops10h 50m
American Airlines
Thu 3/192:16 pm
SDQ
-
SDF
2 stops10h 11m
American Airlines
Deal found 1/27$553
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/209:00 am
SDF
-
SDQ
2 stops13h 46m
United Airlines
Wed 2/256:00 am
SDQ
-
SDF
2 stops15h 09m
United Airlines
Deal found 1/26$578

Find flight deals from Louisville to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$378
(CheapOair)

Popular in

August

Cheapest in

November

Average price

$542
Provider with most accurate pricing for Louisville Intl-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Santo Domingo Las Americas flights.
Search Deals
From Louisville Intl to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Louisville to Santo Domingo that are best for you.

Fly from

Louisville

Fly to

Santo Domingo

Route

Depart

Return

Price

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 3/5

3:33 pm-2:20 pm

1 stop21h 47m

Santo Domingo Las Americas

Wed 3/18

2:59 am-2:33 pm

1 stop11h 34m

$378

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Fri 2/20

9:30 am-2:20 pm

1 stop27h 50m

Santo Domingo Las Americas

Wed 2/25

3:32 pm-2:38 pm

1 stop24h 06m

$453

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Wed 3/11

1:19 pm-5:25 am

2 stops16h 06m

Santo Domingo Las Americas

Sun 3/15

2:30 pm-8:28 pm

1 stop29h 58m

$493

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 4/2

3:33 pm-1:38 am

1 stop10h 05m

Santo Domingo Las Americas

Mon 4/6

2:30 pm-12:19 pm

1 stop21h 49m

$500

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Mon 6/8

9:10 pm-2:32 pm

1 stop17h 22m

Santo Domingo Las Americas

Tue 6/16

3:37 pm-11:30 am

1 stop19h 53m

$510

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Mon 6/8

6:05 am-11:55 pm

1 stop17h 50m

Santo Domingo Las Americas

Fri 6/19

6:00 am-8:57 pm

1 stop14h 57m

$539

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Mon 6/8

6:05 am-11:55 pm

1 stop17h 50m

Santo Domingo Las Americas

Thu 6/18

6:00 am-11:59 pm

2 stops17h 59m

$543

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Mon 6/8

5:45 pm-12:30 pm

2 stops18h 45m

Santo Domingo Las Americas

Tue 6/16

7:25 pm-1:49 pm

2 stops18h 24m

$543

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Mon 6/8

6:05 am-11:55 pm

1 stop17h 50m

Santo Domingo Las Americas

Wed 6/17

7:25 pm-1:49 pm

2 stops18h 24m

$543

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Compare providers for flights from Louisville to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Santo Domingo in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Santo Domingo

What is the cheapest month to book a flight from Louisville to Santo Domingo?

Currently, April is the cheapest month in which you can book a flight from Louisville to Santo Domingo (average of $322). Flying from Louisville to Santo Domingo in January is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with American Airlines from Louisville to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,205 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Crew

8.0

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,205 reviews
American Airlines
7.2
Good
11,205 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Crew

8.0

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Santo Domingo?

    Departing from Louisville to Santo Domingo will take you 21h 47m. Airlines will cover a distance of 1671 mi.

  • What is the cheapest airline to fly from Louisville to Santo Domingo round-trip?

    Flying on American Airlines is currently your cheapest option to Santo Domingo, with prices starting at $517. American Airlines is currently priced 10% below the average price you’ll pay for this route.

  • Can I find deals for flights from Louisville to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Louisville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Santo Domingo.

  • Can I find deals for business class flights from Louisville to Santo Domingo?

    Yes. Cheapflights offers flight deals from Louisville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Santo Domingo?

    Currently, April is the cheapest month in which you can book a flight from Louisville to Santo Domingo (average of $322). Flying from Louisville to Santo Domingo in January is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top airline flying from Louisville to Santo Domingo

Discover the top airline that operate flights from Louisville to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$517Average$566FlexibilityNo cancel feeOn-time71%

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