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Santo Domingo

$414+ Cheap flights from Louisville (SDF) to Santo Domingo (SDQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — SDQ
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Louisville to Santo Domingo

Cheapest flights from Louisville to Santo Domingo
Explore the most affordable flight options available from Louisville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Expedia deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:05 amSDF - SDQ
1 stop20h 49mSpirit Airlines
Wed 12/243:59 amSDQ - SDF
1 stop21h 00mSpirit Airlines
Deal found 12/13$589
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:05 amSDF - SDQ
2 stops29h 25mMultiple Airlines
Wed 12/243:59 amSDQ - SDF
1 stop21h 00mMultiple Airlines
Deal found 12/13$672
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:00 amSDF - SDQ
1 stop7h 32mDelta
Sat 1/103:46 pmSDQ - SDF
1 stop9h 09mDelta
Deal found 12/13$825
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:24 pmSDF - SDQ
2 stops13h 43mAmerican Airlines
Sat 1/104:47 pmSDQ - SDF
1 stop19h 28mAmerican Airlines
Deal found 12/14$875
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:24 pmSDF - SDQ
2 stops13h 43mAmerican Airlines
Thu 12/254:51 pmSDQ - SDF
2 stops16h 59mAmerican Airlines
Deal found 12/13$879

Find flight deals from Louisville to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$414
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$779
Provider with most accurate pricing for Louisville Intl-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Santo Domingo Las Americas flights.
Search Deals
From Louisville Intl to Santo Domingo Las Americas
Search Deals
High demand for flights, 9% potential price rise
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Louisville to Santo Domingo that are best for you.

Fly from

Louisville

Fly to

Santo Domingo

Route

Depart

Return

Price

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Wed 1/28

1:55 pm-2:27 pm

2 stops23h 32m

Santo Domingo Las Americas

Wed 2/4

3:32 pm-2:41 pm

1 stop24h 09m

$414

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Wed 1/28

7:00 am-2:21 pm

1 stop6h 21m

Santo Domingo Las Americas

Wed 2/4

3:46 pm-11:50 pm

1 stop9h 04m

$518

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Wed 3/4

6:15 am-3:06 pm

1 stop7h 51m

Santo Domingo Las Americas

Thu 3/19

1:53 pm-11:59 pm

1 stop10h 06m

$518

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 3/5

6:00 am-3:06 pm

1 stop8h 06m

Santo Domingo Las Americas

Thu 3/19

3:18 pm-11:59 pm

1 stop8h 41m

$518

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Wed 3/4

5:30 am-11:59 pm

2 stops17h 29m

Santo Domingo Las Americas

Thu 3/19

4:05 pm-8:41 am

2 stops16h 36m

$522

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Wed 1/28

1:55 pm-2:27 pm

3 stops23h 32m

Santo Domingo Las Americas

Wed 2/4

12:41 pm-2:41 pm

3 stops27h 00m

$523

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Fri 5/8

7:00 am-1:21 pm

1 stop6h 21m

Santo Domingo Las Americas

Fri 5/15

2:45 pm-11:59 pm

1 stop9h 14m

$528

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Fri 5/8

8:58 am-9:50 pm

2 stops12h 52m

Santo Domingo Las Americas

Fri 5/15

7:55 am-12:14 am

2 stops16h 19m

$532

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Sat 6/6

7:00 am-2:10 pm

1 stop7h 10m

Santo Domingo Las Americas

Sat 6/13

6:00 am-10:09 pm

2 stops16h 09m

$542

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Mon 3/2

1:50 pm-11:46 pm

1 stop8h 56m

Santo Domingo Las Americas

Fri 3/6

4:18 pm-11:59 pm

1 stop8h 41m

$568

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Compare providers for flights from Louisville to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Santo Domingo in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Louisville-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Louisville-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Santo Domingo

What is the cheapest month to book a flight from Louisville to Santo Domingo?

Currently, April is the cheapest month in which you can book a flight from Louisville to Santo Domingo (average of $322). Flying from Louisville to Santo Domingo in January is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated December 15, 2025.
Peruse reviews from past customers who have flown with American Airlines from Louisville to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,052 reviews

Crew

8.0

Overall

7.2

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Food

6.5

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,052 reviews
American Airlines
7.2
Good
11,052 reviews

Crew

8.0

Overall

7.2

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Food

6.5

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Louisville to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Santo Domingo?

    Departing from Louisville to Santo Domingo will take you 6h 21m. Airlines will cover a distance of 1671 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Louisville to Santo Domingo round-trip?

    Flying on American Airlines is currently your cheapest option to Santo Domingo, with prices starting at $514. American Airlines is currently priced 15% below the average price you’ll pay for this route.

  • Can I find deals for flights from Louisville to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Louisville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Santo Domingo.

  • Can I find deals for business class flights from Louisville to Santo Domingo?

    Yes. Cheapflights offers flight deals from Louisville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Santo Domingo?

    Currently, April is the cheapest month in which you can book a flight from Louisville to Santo Domingo (average of $322). Flying from Louisville to Santo Domingo in January is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top airline flying from Louisville to Santo Domingo

Discover the top airline that operate flights from Louisville to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$514Average$566FlexibilityNo cancel feeOn-time71%

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