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Santo Domingo

$337+ Cheap flights from Louisville (SDF) to Santo Domingo (SDQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — SDQ
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Louisville to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$337
(Cheapflightsfares)

Popular in

December

Cheapest in

January

Average price

$544
From Louisville Intl to Santo Domingo Las Americas
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Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Louisville to Santo Domingo

Cheapest flights from Louisville to Santo Domingo
Explore the most affordable flight options available from Louisville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:55 amSDF - SDQ
1 stop5h 55mSpirit Airlines
Sun 11/96:55 pmSDQ - SDF
1 stop16h 04mSpirit Airlines
Deal found 9/9$337
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/56:58 pmSDF - SDQ
1 stop21h 09mSpirit Airlines
Sun 10/123:54 pmSDQ - SDF
1 stop18h 58mSpirit Airlines
Deal found 9/8$340
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/56:58 pmSDF - SDQ
1 stop21h 09mMultiple Airlines
Sun 10/128:58 amSDQ - SDF
2 stops25h 54mMultiple Airlines
Deal found 9/8$409
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/48:23 amSDF - SDQ
2 stops26h 33mMultiple Airlines
Sun 10/53:54 pmSDQ - SDF
1 stop18h 58mMultiple Airlines
Deal found 9/10$410
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/208:23 amSDF - SDQ
1 stop6h 19mSpirit Airlines
Sat 9/273:47 pmSDQ - SDF
2 stops17h 32mSpirit Airlines
Deal found 9/11$415
This Mytrip deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/48:23 amSDF - SDQ
1 stop6h 19mSpirit Airlines
Sun 10/53:54 pmSDQ - SDF
3 stops27h 21mSpirit Airlines
Deal found 9/10$437
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/56:58 pmSDF - SDQ
1 stop21h 09mMultiple Airlines
Sat 10/113:59 pmSDQ - SDF
2 stops40h 59mMultiple Airlines
Deal found 9/8$439
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/56:58 pmSDF - SDQ
1 stop21h 09mMultiple Airlines
Fri 10/105:12 pmSDQ - SDF
2 stops15h 23mMultiple Airlines
Deal found 9/8$445
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:55 amSDF - SDQ
1 stop5h 55mMultiple Airlines
Sun 11/96:10 amSDQ - SDF
2 stops28h 49mMultiple Airlines
Deal found 9/9$446

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Louisville to Santo Domingo that are best for you.

Fly from

Louisville

Fly to

Santo Domingo

Route

Depart

Return

Price

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 11/6

10:55 am-5:50 pm

1 stop5h 55m

Santo Domingo Las Americas

Sun 11/9

6:55 pm-9:59 am

1 stop16h 04m

$337

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Sat 10/4

8:23 am-10:56 am

2 stops26h 33m

Santo Domingo Las Americas

Sun 10/5

3:54 pm-10:52 am

1 stop18h 58m

$410

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Sat 10/4

8:23 am-2:42 pm

1 stop6h 19m

Santo Domingo Las Americas

Sun 10/5

3:54 pm-7:15 pm

3 stops27h 21m

$437

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 11/6

10:55 am-5:50 pm

1 stop5h 55m

Santo Domingo Las Americas

Sun 11/9

6:10 am-9:59 am

2 stops28h 49m

$446

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Mon 3/2

12:40 pm-11:59 pm

2 stops10h 19m

Santo Domingo Las Americas

Fri 3/6

8:00 pm-11:37 am

2 stops16h 37m

$572

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Sun 3/8

6:31 am-10:00 pm

1 stop15h 29m

Santo Domingo Las Americas

Sun 3/15

5:45 am-12:14 am

1 stop18h 29m

$625

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 2/5

1:50 pm-11:46 pm

1 stop8h 56m

Santo Domingo Las Americas

Mon 2/9

2:53 pm-11:23 pm

1 stop9h 30m

$627

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Louisville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Santo Domingo

What is the cheapest month to book a flight from Louisville to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Louisville to Santo Domingo (average of $362). Flying from Louisville to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Louisville to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Louisville to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Santo Domingo?

    Departing from Louisville to Santo Domingo will take you 5h 55m. Airlines will cover a distance of 1671 mi.

  • What are the cheapest airlines flying from Louisville to Santo Domingo round-trip?

    Flying on Delta is currently your cheapest option to Santo Domingo, with prices starting at $513. Another option worth looking into is American Airlines, starting at $514 round trip. Delta is currently priced 24% below the average price you’ll pay for this route.

  • Can I find deals for flights from Louisville to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Louisville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Santo Domingo.

  • Can I find deals for business class flights from Louisville to Santo Domingo?

    Yes. Cheapflights offers flight deals from Louisville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Louisville to Santo Domingo (average of $362). Flying from Louisville to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Louisville to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Louisville to Santo Domingo

Discover the top 2 airlines that operate flights from Louisville to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$513Average$650FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$514Average$568FlexibilityNo cancel feeOn-time71%

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