HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago de los Caballeros

$212+ Cheap flights from Missouri to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — STI
Aug 27 — Sep 31
Wed 8/27
Wed 9/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Santiago de los Caballeros

Keep the following information in mind while searching for Missouri to Santiago de los Caballeros flight deals. Data was last updated August 22, 2025.

Round-trip from

$494
(Kiwi.com)

One-way from

$212
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$581
From Missouri to Santiago de los Caballeros
Search Deals
One-way flight from Missouri to Santiago de los Caballeros
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($92 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Missouri to Santiago de los Caballeros

Cheapest flights from Missouri to Santiago de los Caballeros
Explore the most affordable flight options available from Missouri to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/510:57 amSTL - STI
1 stop22h 41mMultiple Airlines
Sun 10/1211:43 amSTI - STL
2 stops33h 38mMultiple Airlines
Deal found 8/21$494
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/249:59 amMCI - STI
1 stop13h 48mDelta
Sat 9/206:11 amSTI - MCI
1 stop13h 34mDelta
Deal found 8/21$531
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/103:48 pmMCI - STI
2 stops19h 25mAmerican Airlines
Fri 10/171:14 pmSTI - MCI
1 stop10h 45mAmerican Airlines
Deal found 8/21$582
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/56:00 pmSTL - STI
2 stops17h 03mDelta
Sun 10/126:00 amSTI - STL
2 stops15h 23mDelta
Deal found 8/21$644
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/109:50 amMCI - STI
1 stop13h 34mDelta
Fri 10/176:00 amSTI - MCI
1 stop11h 53mDelta
Deal found 8/20$650
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/55:28 amSTL - STI
1 stop5h 59mAmerican Airlines
Sun 10/121:14 pmSTI - STL
1 stop11h 42mAmerican Airlines
Deal found 8/21$650

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 22, 2025.
Use the filters below to find and compare flights from Missouri to Santiago de los Caballeros that are best for you.

Fly from

Missouri

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sun 10/5

10:57 am-10:38 am

1 stop22h 41m

Santiago de los Caballeros

Sun 10/12

11:43 am-8:21 pm

2 stops33h 38m

$494

Kansas CitySantiago de los Caballeros

MCI - STI

MCISTI

Kansas City

Mon 2/2

9:59 am-11:54 pm

1 stop11h 55m

Santiago de los Caballeros

Mon 2/9

6:35 am-6:08 pm

1 stop13h 33m

$525

Kansas CitySantiago de los Caballeros

MCI - STI

MCISTI

Kansas City

Sun 9/21

5:06 am-12:27 pm

1 stop6h 21m

Santiago de los Caballeros

Sat 9/27

1:29 pm-11:59 pm

1 stop11h 30m

$531

Kansas CitySantiago de los Caballeros

MCI - STI

MCISTI

Kansas City

Fri 10/10

3:48 pm-12:13 pm

2 stops19h 25m

Santiago de los Caballeros

Fri 10/17

1:14 pm-10:59 pm

1 stop10h 45m

$582

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sun 10/5

6:00 pm-12:03 pm

2 stops17h 03m

Santiago de los Caballeros

Sun 10/12

6:00 am-8:23 pm

2 stops15h 23m

$644

Kansas CitySantiago de los Caballeros

MCI - STI

MCISTI

Kansas City

Fri 10/10

9:50 am-12:24 am

1 stop13h 34m

Santiago de los Caballeros

Fri 10/17

6:00 am-4:53 pm

1 stop11h 53m

$650

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sun 10/5

5:28 am-12:27 pm

1 stop5h 59m

Santiago de los Caballeros

Sun 10/12

1:14 pm-11:56 pm

1 stop11h 42m

$650

Kansas CitySantiago de los Caballeros

MCI - STI

MCISTI

Kansas City

Sat 9/20

5:15 am-11:03 am

2 stops28h 48m

$212

Kansas CitySantiago de los Caballeros

MCI - STI

MCISTI

Kansas City

Sat 9/20

5:06 am-12:27 pm

1 stop6h 21m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Best time to book a flight from Missouri to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santiago de los Caballeros

What is the cheapest month to book a flight from Missouri to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Missouri to Santiago de los Caballeros (average of $347). Flying from Missouri to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago de los Caballeros from Missouri?

    Located just 6.8 mi from the city center, Santiago de los Caballeros (STI) is the airport most travelers will use when flying to Santiago de los Caballeros from Missouri.

  • How long is the flight from Missouri to Santiago de los Caballeros?

    A quick flight from Missouri to Santiago de los Caballeros can take about 6h 21m. Delta provides one of the quickest options available for as low as $531. Airlines will cover a distance of 1986 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Missouri to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santiago de los Caballeros.

  • Can I find deals for business class flights from Missouri to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Missouri to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from Missouri to Santiago de los Caballeros (average of $347). Flying from Missouri to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Santo Domingo flights
John F Kennedy Intl to Santiago de los Caballeros flights
John F Kennedy Intl to Punta Cana flights
Newark to Santiago de los Caballeros flights
Newark to Santo Domingo flights
Newark to Punta Cana flights
LaGuardia to Punta Cana flights
Dulles Intl to Punta Cana flights
Boston to Santo Domingo flights
Boston to Punta Cana flights
LaGuardia to Santo Domingo flights
LaGuardia to Santiago de los Caballeros flights
Atlanta to Punta Cana flights
O'Hare Intl to Punta Cana flights
Baltimore to Punta Cana flights
Boston to Santiago de los Caballeros flights
Fort Lauderdale to Santo Domingo flights
Fort Lauderdale to Punta Cana flights
Orlando to Santo Domingo flights
Miami to Santo Domingo flights
Philadelphia to Punta Cana flights
Reagan-National to Punta Cana flights
John F Kennedy Intl to Puerto Plata flights
Orlando to Punta Cana flights
Hobby to Punta Cana flights
Miami to Punta Cana flights
Orlando to Santiago de los Caballeros flights
Dallas/Fort Worth to Punta Cana flights
Atlanta to Santo Domingo flights
Norfolk to Punta Cana flights
Minneapolis to Punta Cana flights
Detroit to Punta Cana flights
Hobby to Santo Domingo flights
Dallas/Fort Worth to Santo Domingo flights
George Bush Intcntl to Punta Cana flights
Charlotte to Punta Cana flights
Dulles Intl to Santo Domingo flights
Midway to Punta Cana flights
Los Angeles to Punta Cana flights
San Francisco to Punta Cana flights
Baltimore to Santo Domingo flights
Philadelphia to Santo Domingo flights
LaGuardia to Puerto Plata flights
Denver to Punta Cana flights
Reagan-National to Santo Domingo flights
Indianapolis to Punta Cana flights
George Bush Intcntl to Santo Domingo flights
Miami to Santiago de los Caballeros flights
Seattle to Punta Cana flights
Burlington to Punta Cana flights

Top airline flying from Missouri to Santiago de los Caballeros

Discover the top airline that operate flights from Missouri to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$522Average$755FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.