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Santiago de los Caballeros

$142+ Cheap flights from Missouri to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — STI
nov. 28 — dic. 51
vie. 11/28
vie. 12/5
1 adult, Economy
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Cheap flight deals from Missouri to Santiago de los Caballeros

Keep the following information in mind while searching for Missouri to Santiago de los Caballeros flight deals. Data was last updated octubre 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$418
(Kiwi.com)

One-way from

$142
(Priceline)

Popular in

February

Cheapest in

April

Average price

$559
Provider with most accurate pricing for Lambert-St Louis-Santiago de los Caballeros flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Santiago de los Caballeros flights.
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From Missouri to Santiago de los Caballeros
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One-way flight from Missouri to Santiago de los Caballeros
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Highest demand for flights based on searches. 14% potential increase in price ($117 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Missouri to Santiago de los Caballeros

Cheapest flights from Missouri to Santiago de los Caballeros
Explore the most affordable flight options available from Missouri to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 29, 2025.

This CheapOair deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/286:15 pmMCI - STI
1 stop6h 27mSpirit Airlines
sáb. 1/106:18 pmSTI - MCI
2 stops20h 21mSpirit Airlines
Deal found 10/28$631
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/286:36 pmMCI - STI
2 stops17h 48mAmerican Airlines
sáb. 1/106:00 amSTI - MCI
2 stops19h 12mAmerican Airlines
Deal found 10/27$650
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/286:35 pmMCI - STI
2 stops27h 16mUnited Airlines
vie. 10/315:00 amSTI - MCI
2 stops17h 50mUnited Airlines
Deal found 10/28$663
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/135:30 pmSTL - STI
2 stops20h 02mAmerican Airlines
sáb. 12/203:24 pmSTI - STL
1 stop9h 11mAmerican Airlines
Deal found 10/28$667
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/175:54 pmSTL - STI
2 stops21h 33mAmerican Airlines
mié. 12/246:57 amSTI - STL
1 stop11h 41mAmerican Airlines
Deal found 10/26$742
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/283:03 pmSTL - STI
2 stops20h 10mAmerican Airlines
mié. 11/124:35 pmSTI - STL
2 stops17h 52mAmerican Airlines
Deal found 10/27$1,146

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
Use the filters below to find and compare flights from Missouri to Santiago de los Caballeros that are best for you.

Fly from

Missouri

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

Kansas CitySantiago de los Caballeros

MCI - STI

MCISTI

Kansas City

jue. 1/22

1:44 pm-5:06 pm

2 stops25h 22m

Santiago de los Caballeros

jue. 1/29

6:18 pm-11:08 am

1 stop18h 50m

$418

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

mié. 1/14

12:00 pm-12:50 am

2 stops10h 50m

Santiago de los Caballeros

vie. 1/23

6:39 am-8:45 pm

2 stops16h 06m

$522

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

lun. 1/12

12:00 pm-12:50 am

2 stops10h 50m

Santiago de los Caballeros

mié. 1/21

6:39 am-8:45 pm

2 stops16h 06m

$522

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

mar. 1/13

10:19 am-12:50 am

2 stops12h 31m

Santiago de los Caballeros

vie. 1/23

6:39 am-8:45 pm

2 stops16h 06m

$522

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

mar. 1/13

10:19 am-12:50 am

2 stops12h 31m

Santiago de los Caballeros

mié. 1/21

6:39 am-8:45 pm

2 stops16h 06m

$522

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

lun. 1/12

10:19 am-12:50 am

2 stops12h 31m

Santiago de los Caballeros

vie. 1/23

6:39 am-8:45 pm

2 stops16h 06m

$522

Kansas CitySantiago de los Caballeros

MCI - STI

MCISTI

Kansas City

jue. 1/22

9:57 am-12:50 am

1 stop12h 53m

Santiago de los Caballeros

mar. 1/27

6:39 am-7:19 pm

1 stop14h 40m

$526

Kansas CitySantiago de los Caballeros

MCI - STI

MCISTI

Kansas City

jue. 1/22

9:57 am-8:34 pm

1 stop8h 37m

Santiago de los Caballeros

jue. 1/29

6:39 am-7:19 pm

1 stop14h 40m

$526

Kansas CitySantiago de los Caballeros

MCI - STI

MCISTI

Kansas City

sáb. 1/3

6:15 pm-2:42 am

1 stop6h 27m

Santiago de los Caballeros

vie. 1/16

6:18 pm-12:39 pm

2 stops20h 21m

$532

Kansas CitySantiago de los Caballeros

MCI - STI

MCISTI

Kansas City

lun. 3/9

9:59 am-11:27 pm

1 stop12h 28m

Santiago de los Caballeros

jue. 3/12

6:00 am-6:08 pm

1 stop13h 08m

$534

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 21 results
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Best time to book a flight from Missouri to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santiago de los Caballeros

What is the cheapest month to book a flight from Missouri to Santiago de los Caballeros?

Currently, April is the cheapest month in which you can book a flight from Missouri to Santiago de los Caballeros (average of $374). Flying from Missouri to Santiago de los Caballeros in June is currently the most expensive (average of $527). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago de los Caballeros from Missouri?

    Located just 6.8 mi from the city center, Santiago de los Caballeros (STI) is the airport most travelers will use when flying to Santiago de los Caballeros from Missouri.

  • How long is the flight from Missouri to Santiago de los Caballeros?

    A quick flight from Missouri to Santiago de los Caballeros can take about 10h 50m. Spirit Airlines provides one of the quickest options available for as low as $522. Airlines will cover a distance of 1782 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Missouri to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santiago de los Caballeros.

  • Can I find deals for business class flights from Missouri to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Missouri to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Santiago de los Caballeros?

    Currently, April is the cheapest month in which you can book a flight from Missouri to Santiago de los Caballeros (average of $374). Flying from Missouri to Santiago de los Caballeros in June is currently the most expensive (average of $527). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Missouri to Santiago de los Caballeros

Discover the top airline that operate flights from Missouri to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$522Average$749FlexibilityNo cancel feeOn-time71%

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