How long is the flight from Harlingen, Texas to Santiago de los Caballeros?

For as low as $653, American Airlines can have you in Santiago de los Caballeros from Harlingen, Texas in 24h 36m. Airlines will cover a distance of 1781 mi.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What is the cheapest time of day to fly from HRL to STI?

When flying from Harlingen, Texas to Santiago de los Caballeros, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Harlingen, Texas-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harlingen, Texas-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harlingen, Texas-Santiago de los Caballeros flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Harlingen, Texas-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harlingen, Texas-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

How can I find direct flights from Harlingen to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harlingen to Santiago de los Caballeros.

Can I find deals for business class flights from Harlingen to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Harlingen to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$563+ Flights from Harlingen, TX to Santiago de los Caballeros

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Cheap flight deals from Harlingen to Santiago de los Caballeros

Cheapest flights from Harlingen to Santiago de los Caballeros
Explore the most affordable flight options available from Harlingen to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

Fri 8/1410:02 am

HRL

STI

2 stops25h 29m

American Airlines

Mon 8/241:31 pm

STI

HRL

2 stops21h 01m

American Airlines

Deal found 1/27

$563

Thu 10/226:20 pm

HRL

STI

2 stops16h 50m

American Airlines

Mon 11/24:36 pm

STI

HRL

2 stops21h 02m

American Airlines

Deal found 1/27

$603

Thu 4/3010:47 am

HRL

STI

2 stops24h 36m

American Airlines

Mon 5/111:32 pm

STI

HRL

2 stops21h 45m

American Airlines

Deal found 1/27

$653

Tue 2/39:20 am

HRL

STI

2 stops12h 31m

United Airlines

Fri 2/612:52 pm

STI

HRL

2 stops24h 34m

United Airlines

Deal found 1/24

$723

Best flights from Harlingen to Santiago de los Caballeros
Discover carefully curated flight deals from Harlingen to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 27, 2026.

Thu 4/3010:47 am

HRL

STI

2 stops24h 36m

American Airlines

Mon 5/111:32 pm

STI

HRL

2 stops21h 45m

American Airlines

Deal found 1/27

$653

Last-minute flights from Harlingen to Santiago de los Caballeros
Discover last-minute flight deals from Harlingen to Santiago de los Caballeros. Data last updated January 27, 2026 and is based on user searches.

Tue 2/39:20 am

HRL

STI

2 stops12h 31m

United Airlines

Fri 2/612:52 pm

STI

HRL

2 stops24h 34m

United Airlines

Deal found 1/24

$723

Find flight deals from Harlingen to Santiago de los Caballeros

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars

Provider with most accurate pricing for Harlingen Valley Intl-Santiago de los Caballeros flight deals.

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Use the filters below to find and compare flights from Harlingen to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HarlingenSantiago de los Caballeros

HRL - STI

HRLSTI

Harlingen Valley Intl

Thu 4/30

10:47 am-12:23 pm

2 stops24h 36m

Santiago de los Caballeros

Mon 5/11

1:32 pm-10:17 am

2 stops21h 45m

$653

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Most accurate provider: When it comes to deals on Harlingen, Texas-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harlingen, Texas-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harlingen, Texas-Santiago de los Caballeros flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Harlingen, Texas-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harlingen, Texas-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harlingen to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Harlingen with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Harlingen, Texas to Santiago de los Caballeros?
For as low as $653, American Airlines can have you in Santiago de los Caballeros from Harlingen, Texas in 24h 36m. Airlines will cover a distance of 1781 mi.
Can I find deals for flights from Harlingen to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Harlingen to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Harlingen to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harlingen to Santiago de los Caballeros.
Can I find deals for business class flights from Harlingen to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Harlingen to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$563+ Cheap flights from Harlingen, TX (HRL) to Santiago de los Caballeros (STI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Harlingen to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Harlingen to Santiago de los Caballeros

Cheapest flights from Harlingen to Santiago de los CaballerosExplore the most affordable flight options available from Harlingen to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

Explore the most affordable flight options available from Harlingen to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

Find flight deals from Harlingen to Santiago de los Caballeros

Most accurate provider

Most trusted provider

Cheapflights Fare Finder

Use the filters below to find and compare flights from Harlingen to Santiago de los Caballeros that are best for you.

Best time to book a flight from Harlingen to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Harlingen with our price prediction graph.

Related info for your journey

Find useful and relevant information for your journey from Harlingen to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Harlingen, Texas to Santiago de los Caballeros?

Can I find deals for flights from Harlingen to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Harlingen to Santiago de los Caballeros?

Can I find deals for business class flights from Harlingen to Santiago de los Caballeros?

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Alternative routes for Harlingen to Santiago de los Caballeros

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Cheapest flights from Harlingen to Santiago de los Caballeros
Explore the most affordable flight options available from Harlingen to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.