How long is the flight from Durham to Santiago de los Caballeros?

Departing from Durham to Santiago de los Caballeros will take you 11h 50m. Durham and Santiago de los Caballeros are separated by a distance of 1241 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines to fly from Durham to Santiago de los Caballeros one-way?

To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $162. American Airlines flights start at $162 while deals on Delta start at $205 one-way.

What is the cheapest day to fly from Durham to Santiago de los Caballeros?

Travelers seeking maximum savings on their Durham to Santiago de los Caballeros flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What are the most popular airlines that fly from Durham to Santiago de los Caballeros?

American Airlines, JetBlue and Delta are the most popular airlines when flying from Durham to Santiago de los Caballeros.

How far in advance should I book a flight from Durham to Santiago de los Caballeros?

Find a great deal and save up to 145% by booking at least 30 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Durham to Santiago de los Caballeros within the next two weeks, with the cheapest ticket starting at $442.

What is the cheapest month to fly from Durham to Santiago de los Caballeros?

The best pricing can be found in the month of November. Prices to Santiago de los Caballeros from Durham average $579. You can even find prices in November for less than $579, as users have found deals to Santiago de los Caballeros from as low as $266. The month of December appears to be one of the more expensive times to travel to Santiago de los Caballeros from Durham. Flying in the targeted month can save you up to 22%.

What airport do you fly into for flights to Santiago de los Caballeros from Durham?

Santiago de los Caballeros (STI) is the airport you will fly into if you book a flight from Durham to Santiago de los Caballeros. You should not have trouble finding flights to Santiago from Durham; the airport handles an average of 0 inbound flights from Durham per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Santiago de los Caballeros airport from Durham. It is only a 6.8 mi journey from Santiago (STI) to Santiago de los Caballeros’s city center.

How can I find direct flights from Durham to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santiago de los Caballeros.

Can I find deals for business class flights from Durham to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Durham to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$162+ Cheap Flights from Durham to Santiago de los Caballeros

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Durham to Santiago de los Caballeros are usually found in November or March, booked 29 days in advance, depart on a Tuesday or Monday and return on a Friday

Cheap flight deals from Durham to Santiago de los Caballeros

Round-trip from	$345 (Delta)
One-way from	$162 (United Airlines)
Popular in	December
Cheapest in	November
Average price	$496

From Durham to Santiago de los Caballeros

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One-way flight from Durham to Santiago de los Caballeros

Search Deals

Highest demand for flights based on searches. 0% potential increase in price ($3 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from Durham to Santiago de los Caballeros

Cheapest flights from Durham to Santiago de los Caballeros
Explore the most affordable flight options available from Durham to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

Mon 10/67:16 amRDU - STI

1 stop11h 50mDelta

Fri 10/248:31 pmSTI - RDU

1 stop14h 17mDelta

Deal found 9/15

$345

Sun 11/25:00 amRDU - STI

1 stop8h 33mAmerican Airlines

Sat 11/87:00 amSTI - RDU

1 stop16h 04mAmerican Airlines

Deal found 9/13

$347

Sat 9/277:10 amRDU - STI

1 stop12h 01mDelta

Tue 9/306:11 amSTI - RDU

1 stop8h 06mDelta

Deal found 9/14

$353

Thu 10/307:40 pmRDU - STI

2 stops16h 33mAmerican Airlines

Sun 11/24:35 pmSTI - RDU

2 stops17h 48mAmerican Airlines

Deal found 9/14

$356

Sun 10/54:32 pmRDU - STI

2 stops19h 41mAmerican Airlines

Thu 10/231:14 pmSTI - RDU

1 stop10h 42mAmerican Airlines

Deal found 9/14

$357

Tue 9/307:16 pmRDU - STI

2 stops17h 11mAmerican Airlines

Sun 10/51:29 pmSTI - RDU

2 stops21h 02mAmerican Airlines

Deal found 9/14

$358

Sun 10/52:55 pmRDU - STI

2 stops21h 18mAmerican Airlines

Fri 10/241:14 pmSTI - RDU

1 stop9h 00mAmerican Airlines

Deal found 9/15

$361

Fri 10/319:09 amRDU - STI

1 stop25h 29mSpirit Airlines

Sun 11/96:18 pmSTI - RDU

1 stop23h 06mSpirit Airlines

Deal found 9/14

$367

Fri 11/75:19 pmRDU - STI

1 stop22h 47mSpirit Airlines

Sun 11/96:18 pmSTI - RDU

1 stop23h 06mSpirit Airlines

Deal found 9/14

$372

Best flights from Durham to Santiago de los Caballeros
Discover carefully curated flight deals from Durham to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2025.

Mon 10/67:16 amRDU - STI

1 stop11h 50mDelta

Fri 10/248:31 pmSTI - RDU

1 stop14h 17mDelta

Deal found 9/15

$345

Sun 11/27:03 amRDU - STI

2 stops12h 48mAmerican Airlines

Sat 11/87:00 amSTI - RDU

2 stops13h 04mAmerican Airlines

Deal found 9/14

$352

Sun 3/14:13 pmRDU - STI

1 stop11h 42mJetBlue

Thu 3/510:07 amSTI - RDU

1 stop7h 53mJetBlue

Deal found 9/13

$373

Mon 3/910:00 amRDU - STI

1 stop8h 16mDelta

Thu 3/126:00 amSTI - RDU

1 stop8h 21mDelta

Deal found 9/14

$347

Sun 10/54:32 pmRDU - STI

2 stops19h 41mAmerican Airlines

Wed 10/221:14 pmSTI - RDU

2 stops18h 57mAmerican Airlines

Deal found 9/14

$357

Sun 3/87:10 amRDU - STI

1 stop16h 17mDelta

Thu 3/126:00 amSTI - RDU

1 stop8h 21mDelta

Deal found 9/14

$347

Sun 10/54:20 pmRDU - STI

1 stop20h 30mJetBlue

Wed 10/225:50 amSTI - RDU

1 stop10h 50mJetBlue

Deal found 9/14

$395

Thu 11/65:25 pmRDU - STI

1 stop8h 33mJetBlue

Tue 11/114:41 amSTI - RDU

1 stop12h 34mJetBlue

Deal found 9/14

$399

Last-minute flights from Durham to Santiago de los Caballeros
Discover last-minute flight deals from Durham to Santiago de los Caballeros. Data last updated September 15, 2025 and is based on user searches.

Sat 9/277:10 amRDU - STI

1 stop12h 01mDelta

Tue 9/306:11 amSTI - RDU

1 stop8h 06mDelta

Deal found 9/14

$353

Tue 9/307:16 pmRDU - STI

2 stops17h 11mAmerican Airlines

Sun 10/51:29 pmSTI - RDU

2 stops21h 02mAmerican Airlines

Deal found 9/14

$358

Sun 10/54:32 pmRDU - STI

2 stops19h 41mAmerican Airlines

Wed 10/221:14 pmSTI - RDU

2 stops18h 57mAmerican Airlines

Deal found 9/14

$357

Sun 10/59:09 amRDU - STI

1 stop25h 29mSpirit Airlines

Thu 10/2311:43 amSTI - RDU

1 stop26h 37mSpirit Airlines

Deal found 9/14

$376

Mon 10/67:16 amRDU - STI

1 stop11h 50mDelta

Fri 10/248:31 pmSTI - RDU

1 stop14h 17mDelta

Deal found 9/15

$345

Fri 10/179:09 amRDU - STI

1 stop25h 29mMultiple Airlines

Mon 10/2711:43 amSTI - RDU

2 stops28h 56mMultiple Airlines

Deal found 9/15

$383

Thu 10/307:40 pmRDU - STI

2 stops16h 33mAmerican Airlines

Sun 11/24:35 pmSTI - RDU

2 stops17h 48mAmerican Airlines

Deal found 9/14

$356

Fri 10/319:09 amRDU - STI

1 stop25h 29mSpirit Airlines

Sun 11/96:18 pmSTI - RDU

1 stop23h 06mSpirit Airlines

Deal found 9/14

$367

One-way flights from Durham to Santiago de los Caballeros
Search for one-way flight options from Durham to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated September 15, 2025.

Sun 11/25:00 amRDU - STI

1 stop13h 51mAmerican Airlines

Deal found 9/14

$162

Wed 12/37:21 pmRDU - STI

2 stops19h 11mAmerican Airlines

Deal found 9/14

$168

Thu 9/252:25 pmRDU - STI

1 stop10h 09mDelta

Deal found 9/15

$205

Wed 12/36:20 amRDU - STI

3 stops33h 46mSpirit Airlines

Deal found 9/14

$228

Sun 11/25:00 amRDU - STI

3 stops28h 38mMultiple Airlines

Deal found 9/14

$230

Wed 9/245:16 pmRDU - STI

2 stops19h 11mAmerican Airlines

Deal found 9/13

$236

Wed 9/246:45 amRDU - STI

3 stops30h 14mMultiple Airlines

Deal found 9/13

$257

Thu 9/254:32 pmRDU - STI

2 stops19h 55mAmerican Airlines

Deal found 9/14

$323

Cheapflights Fare Finder

Use the filters below to find and compare flights from Durham to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Mon 10/6

7:16 am-7:06 pm

1 stop11h 50m

Santiago de los Caballeros

Fri 10/24

8:31 pm-10:48 am

1 stop14h 17m

$345

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Mon 3/9

10:00 am-6:16 pm

1 stop8h 16m

Santiago de los Caballeros

Thu 3/12

6:00 am-2:21 pm

1 stop8h 21m

$347

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sun 3/8

7:10 am-11:27 pm

1 stop16h 17m

Santiago de los Caballeros

Thu 3/12

6:00 am-2:21 pm

1 stop8h 21m

$347

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sun 11/2

7:03 am-8:51 pm

2 stops12h 48m

Santiago de los Caballeros

Sat 11/8

7:00 am-7:04 pm

2 stops13h 04m

$352

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sun 10/5

4:32 pm-12:13 pm

2 stops19h 41m

Santiago de los Caballeros

Wed 10/22

1:14 pm-8:11 am

2 stops18h 57m

$357

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sun 3/1

4:13 pm-4:55 am

1 stop11h 42m

Santiago de los Caballeros

Thu 3/5

10:07 am-5:00 pm

1 stop7h 53m

$373

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sun 10/5

4:20 pm-12:50 pm

1 stop20h 30m

Santiago de los Caballeros

Wed 10/22

5:50 am-4:40 pm

1 stop10h 50m

$395

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Thu 11/6

5:25 pm-2:58 am

1 stop8h 33m

Santiago de los Caballeros

Tue 11/11

4:41 am-4:15 pm

1 stop12h 34m

$399

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Wed 12/3

3:15 pm-11:51 pm

1 stop7h 36m

$162

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sun 11/2

11:16 am-8:51 pm

2 stops8h 35m

$162

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 18 results

Best time to book a flight from Durham to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Durham with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santiago de los Caballeros

How far ahead should I book a flight from Durham to Santiago de los Caballeros?

The best time to book flights from Durham to Santiago de los Caballeros is 29 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Durham to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Durham to Santiago de los Caballeros (average of $347). Flying from Durham to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to STI?

When flying from Durham to Santiago de los Caballeros, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Santiago de los Caballeros

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Durham to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,954 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,954 reviews

Delta

8.0

Very good

7,954 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,929 reviews

Delta

8.0

Very good

7,954 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,954 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

JetBlue

7.2

Good

2,912 reviews

Delta

8.0

Very good

7,954 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly into for flights to Santiago de los Caballeros from Durham?
Santiago de los Caballeros (STI) is the airport you will fly into if you book a flight from Durham to Santiago de los Caballeros. You should not have trouble finding flights to Santiago from Durham; the airport handles an average of 0 inbound flights from Durham per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Santiago de los Caballeros airport from Durham. It is only a 6.8 mi journey from Santiago (STI) to Santiago de los Caballeros’s city center.
How long is the flight from Durham to Santiago de los Caballeros?
Departing from Durham to Santiago de los Caballeros will take you 11h 50m. Durham and Santiago de los Caballeros are separated by a distance of 1241 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines to fly from Durham to Santiago de los Caballeros one-way?
To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $162. American Airlines flights start at $162 while deals on Delta start at $205 one-way.
Can I find deals for flights from Durham to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Durham to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Durham to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santiago de los Caballeros.
Can I find deals for business class flights from Durham to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Durham to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Durham to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from Durham to Santiago de los Caballeros (average of $347). Flying from Durham to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Durham to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$180	Average$452	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$376	Average$634	FlexibilityNo cancel fee	On-time69%
JetBlue	Cheapest$403	Average$575	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$448	Average$732	FlexibilityNo cancel fee	On-time71%

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$162+ Cheap flights from Durham, NC to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Durham to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Durham to Santiago de los Caballeros are usually found in November or March, booked 29 days in advance, depart on a Tuesday or Monday and return on a Friday

Cheap flight deals from Durham to Santiago de los Caballeros

Keep the following information in mind while searching for Durham to Santiago de los Caballeros flight deals. Data was last updated September 15, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Durham to Santiago de los Caballeros

Cheapest flights from Durham to Santiago de los CaballerosExplore the most affordable flight options available from Durham to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

Explore the most affordable flight options available from Durham to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Durham to Santiago de los Caballeros that are best for you.

Best time to book a flight from Durham to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Durham with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santiago de los Caballeros

How far ahead should I book a flight from Durham to Santiago de los Caballeros?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Santiago de los Caballeros. Price data was last updated on September 12, 2025.

What is the cheapest month to book a flight from Durham to Santiago de los Caballeros?

What is the cheapest time of day to fly from DU8 to STI?

Find hourly flight availability from Durham to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Reviews of airlines servicing Santiago de los Caballeros

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Durham to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Durham to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santiago de los Caballeros from Durham?

How long is the flight from Durham to Santiago de los Caballeros?

What are the cheapest airlines to fly from Durham to Santiago de los Caballeros one-way?

Can I find deals for flights from Durham to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Durham to Santiago de los Caballeros?

Can I find deals for business class flights from Durham to Santiago de los Caballeros?

What is the cheapest month to book a flight from Durham to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Durham to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Durham to Santiago de los Caballeros

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Cheapest flights from Durham to Santiago de los Caballeros
Explore the most affordable flight options available from Durham to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.