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Santiago de los Caballeros

$136+ Cheap flights from Durham, NC to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — STI
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheapflights Tip: The best prices from Durham to Santiago de los Caballeros are usually found in November or February, booked 89 days in advance, depart on a Tuesday or Monday and return on a Friday

Cheap flight deals from Durham to Santiago de los Caballeros

Cheapest flights from Durham to Santiago de los Caballeros
Explore the most affordable flight options available from Durham to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This Priceline deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/279:47 pmRDU - STI
1 stop12h 05mMultiple Airlines
Tue 12/3011:53 pmSTI - RDU
1 stop10h 06mMultiple Airlines
Deal found 12/16$475
This Priceline deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:30 amRDU - STI
1 stop6h 53mJetBlue
Wed 12/3111:53 pmSTI - RDU
1 stop10h 06mJetBlue
Deal found 12/16$505
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:57 pmRDU - STI
2 stops11h 45mMultiple Airlines
Sat 12/273:43 amSTI - RDU
1 stop14h 12mMultiple Airlines
Deal found 12/16$523
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:53 pmRDU - STI
2 stops9h 49mMultiple Airlines
Sun 12/283:43 amSTI - RDU
1 stop14h 12mMultiple Airlines
Deal found 12/16$624
This Trip.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:16 pmRDU - STI
1 stop9h 34mMultiple Airlines
Mon 12/293:43 amSTI - RDU
2 stops21h 30mMultiple Airlines
Deal found 12/16$641
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:45 amRDU - STI
1 stop15h 49mDelta
Mon 12/298:45 pmSTI - RDU
1 stop14h 47mDelta
Deal found 12/16$643
This Faresmojo deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:35 pmRDU - STI
1 stop14h 40mJetBlue
Sat 1/311:36 amSTI - RDU
1 stop7h 04mJetBlue
Deal found 12/16$644
This Expedia deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:34 pmRDU - STI
2 stops22h 14mJetBlue
Tue 1/209:30 amSTI - RDU
2 stops29h 20mJetBlue
Deal found 12/15$648
This Priceline deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:30 amRDU - STI
1 stop7h 23mJetBlue
Tue 12/3011:53 pmSTI - RDU
1 stop10h 06mJetBlue
Deal found 12/16$683

Find flight deals from Durham to Santiago de los Caballeros

Keep the following information in mind while searching for Durham to Santiago de los Caballeros flight deals. Data was last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$300
(American Airlines)

One-way from

$136
(Expedia)

Popular in

December

Cheapest in

November

Average price

$695
Provider with most accurate pricing for Raleigh-Durham-Santiago de los Caballeros flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Santiago de los Caballeros flights.
Search Deals
From Durham to Santiago de los Caballeros
Search Deals
One-way flight from Durham to Santiago de los Caballeros
Search Deals
High demand for flights, 2% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Durham to Santiago de los Caballeros that are best for you.

Fly from

Durham

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Wed 1/14

6:00 am-9:46 pm

1 stop14h 46m

Santiago de los Caballeros

Wed 1/21

6:00 am-9:39 pm

1 stop16h 39m

$300

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sat 1/31

11:51 am-9:46 pm

1 stop8h 55m

Santiago de los Caballeros

Wed 2/4

4:33 pm-11:59 pm

1 stop8h 26m

$300

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Mon 1/12

7:35 am-9:46 pm

1 stop13h 11m

Santiago de los Caballeros

Thu 1/22

6:00 am-6:54 pm

1 stop13h 54m

$300

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Wed 1/21

11:51 am-9:46 pm

1 stop8h 55m

Santiago de los Caballeros

Mon 1/26

4:33 pm-11:01 am

1 stop19h 28m

$307

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Thu 2/5

7:05 am-8:34 pm

1 stop12h 29m

Santiago de los Caballeros

Sun 2/8

9:59 pm-10:18 am

1 stop13h 19m

$318

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Thu 2/5

7:54 pm-3:32 pm

1 stop18h 38m

Santiago de los Caballeros

Thu 2/12

8:00 am-5:15 pm

1 stop10h 15m

$321

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sat 2/21

5:03 am-10:05 pm

2 stops16h 02m

Santiago de los Caballeros

Wed 2/25

8:00 am-5:35 pm

1 stop10h 35m

$334

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Thu 1/29

2:51 pm-12:25 am

1 stop8h 34m

Santiago de los Caballeros

Thu 2/5

12:12 pm-11:08 pm

1 stop11h 56m

$338

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sat 1/24

4:19 pm-12:49 pm

1 stop19h 30m

$136

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Thu 2/5

11:51 am-9:46 pm

1 stop8h 55m

$138

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 17 results
1
2

Best time to book a flight from Durham to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santiago de los Caballeros

How far ahead should I book a flight from Durham to Santiago de los Caballeros?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Santiago de los Caballeros. Price data was last updated on December 12, 2025.

The best time to book flights from Durham to Santiago de los Caballeros is 89 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Durham to Santiago de los Caballeros?

Currently, October is the cheapest month in which you can book a flight from Durham to Santiago de los Caballeros (average of $146). Flying from Durham to Santiago de los Caballeros in March is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to STI?

Find hourly flight availability from Durham to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

It’s optimal to fly from Durham to Santiago de los Caballeros in the afternoon. By choosing this option you can save up to 15% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated December 16, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Durham to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,010 reviews

Food

7.3

Entertainment

7.9

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,010 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Entertainment

7.9

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,094 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Entertainment

7.9

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Entertainment

7.9

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
JetBlue
7.2
Good
2,894 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Entertainment

7.9

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Durham to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago de los Caballeros from Durham?

    Santiago de los Caballeros (STI) is the airport you will fly into if you book a flight from Durham to Santiago de los Caballeros. You should not have trouble finding flights to Santiago from Durham; the airport handles an average of 0 inbound flights from Durham per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Santiago de los Caballeros airport from Durham. It is only a 6.8 mi journey from Santiago (STI) to Santiago de los Caballeros’s city center.

  • How long is the flight from Durham to Santiago de los Caballeros?

    Departing from Durham to Santiago de los Caballeros will take you 14h 46m. Durham and Santiago de los Caballeros are separated by a distance of 1241 mi.

  • What are the cheapest airlines to fly from Durham to Santiago de los Caballeros one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $199. JetBlue flights start at $200 while deals on United Airlines start at $204 one-way.

  • Can I find deals for flights from Durham to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Durham to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santiago de los Caballeros.

  • Can I find deals for business class flights from Durham to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Durham to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Santiago de los Caballeros?

    Currently, October is the cheapest month in which you can book a flight from Durham to Santiago de los Caballeros (average of $146). Flying from Durham to Santiago de los Caballeros in March is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Durham to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Durham to Santiago de los Caballeros

Discover the top 4 airlines that operate flights from Durham to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$180Average$436FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$299Average$607FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$349Average$500FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$394Average$640FlexibilityNo cancel feeOn-time71%

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