$399+ Cheap flights from Colorado to Santiago de los Caballeros (STI)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — STI
Mar 5 — Mar 121
1 adult, Economy
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Find cheap flights from Colorado to Santiago de los Caballeros with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Colorado to Santiago de los Caballeros
Cheapest
Best
Last-minute
Cheapest flights from Colorado to Santiago de los CaballerosExplore the most affordable flight options available from Colorado to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Colorado to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:15 am
COS
- STI
2 stops16h 07m
Delta
Mon 4/278:59 pm
STI
- COS
2 stops17h 18m
Delta
Deal found 2/2![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:39 pm
COS
- STI
2 stops20h 44m
American Airlines
Wed 4/291:32 pm
STI
- COS
2 stops28h 51m
American Airlines
Deal found 2/1![American Airlines logo]()
$415
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:59 pm
DEN
- STI
1 stop11h 49m
JetBlue
Tue 4/143:34 am
STI
- DEN
1 stop13h 56m
JetBlue
Deal found 2/1![JetBlue logo]()
$426
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:59 pm
DEN
- STI
1 stop12h 36m
JetBlue
Wed 3/118:29 am
STI
- DEN
2 stops15h 49m
JetBlue
Deal found 2/2![JetBlue logo]()
$440
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:55 am
COS
- STI
2 stops29h 38m
Delta
Sat 5/26:00 am
STI
- COS
2 stops31h 12m
Delta
Deal found 2/2![Delta logo]()
$455
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:22 pm
COS
- STI
2 stops22h 01m
American Airlines
Tue 4/281:32 pm
STI
- COS
2 stops24h 20m
American Airlines
Deal found 2/2![American Airlines logo]()
$473
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:22 pm
COS
- STI
2 stops22h 01m
American Airlines
Thu 4/301:32 pm
STI
- COS
2 stops28h 51m
American Airlines
Deal found 2/2![American Airlines logo]()
$491
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:41 am
COS
- STI
2 stops28h 42m
American Airlines
Thu 4/301:32 pm
STI
- COS
2 stops28h 51m
American Airlines
Deal found 2/2![American Airlines logo]()
$509
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:15 am
COS
- STI
2 stops16h 07m
Delta
Wed 4/296:00 am
STI
- COS
2 stops16h 20m
Delta
Deal found 2/2![Delta logo]()
$511
This KAYAK deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/611:40 am
DEN
- STI
1 stop12h 13m
JetBlue
Mon 2/1611:09 pm
STI
- DEN
1 stop13h 37m
JetBlue
Deal found 2/2![JetBlue logo]()
$542
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:13 pm
COS
- STI
2 stops17h 10m
American Airlines
Sun 4/261:32 pm
STI
- COS
2 stops25h 17m
American Airlines
Deal found 2/2![American Airlines logo]()
$551
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:35 pm
COS
- STI
2 stops16h 22m
United Airlines
Wed 9/236:00 am
STI
- COS
2 stops19h 59m
United Airlines
Deal found 2/2![United Airlines logo]()
$565
Best flights from Colorado to Santiago de los CaballerosDiscover carefully curated flight deals from Colorado to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Colorado to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:15 am
COS
- STI
2 stops16h 07m
Delta
Mon 4/278:59 pm
STI
- COS
2 stops17h 18m
Delta
Deal found 2/2![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:39 pm
COS
- STI
2 stops20h 44m
American Airlines
Wed 4/291:32 pm
STI
- COS
2 stops28h 51m
American Airlines
Deal found 2/1![American Airlines logo]()
$415
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:59 pm
DEN
- STI
1 stop11h 49m
JetBlue
Tue 4/143:34 am
STI
- DEN
1 stop13h 56m
JetBlue
Deal found 2/1![JetBlue logo]()
$426
This Orbitz deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2710:59 pm
DEN
- STI
2 stops30h 17m
Multiple Airlines
Sun 4/511:40 am
STI
- DEN
1 stop13h 13m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$606
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:59 pm
DEN
- STI
1 stop12h 36m
JetBlue
Wed 3/118:29 am
STI
- DEN
2 stops15h 49m
JetBlue
Deal found 2/2![JetBlue logo]()
$440
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:13 pm
COS
- STI
2 stops20h 57m
Delta
Sat 5/26:00 am
STI
- COS
2 stops31h 12m
Delta
Deal found 2/2![Delta logo]()
$455
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:41 am
COS
- STI
2 stops28h 42m
American Airlines
Tue 4/281:32 pm
STI
- COS
2 stops24h 20m
American Airlines
Deal found 2/2![American Airlines logo]()
$473
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:55 am
COS
- STI
2 stops29h 38m
Delta
Sat 5/26:00 am
STI
- COS
2 stops31h 12m
Delta
Deal found 2/2![Delta logo]()
$455
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:22 pm
COS
- STI
2 stops22h 01m
American Airlines
Tue 4/281:32 pm
STI
- COS
2 stops24h 20m
American Airlines
Deal found 2/2![American Airlines logo]()
$473
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:15 am
COS
- STI
2 stops16h 07m
Delta
Mon 4/278:59 pm
STI
- COS
2 stops17h 18m
Delta
Deal found 2/2![Delta logo]()
$455
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:15 am
COS
- STI
2 stops27h 55m
Delta
Fri 5/18:59 pm
STI
- COS
2 stops28h 07m
Delta
Deal found 2/2![Delta logo]()
$455
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:55 am
COS
- STI
2 stops29h 38m
Delta
Mon 4/278:59 pm
STI
- COS
2 stops17h 18m
Delta
Deal found 2/2![Delta logo]()
$455
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 am
DEN
- STI
2 stops12h 30m
American Airlines
Wed 3/117:00 am
STI
- DEN
2 stops17h 40m
American Airlines
Deal found 2/2![American Airlines logo]()
$583
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:55 am
COS
- STI
2 stops29h 38m
Delta
Wed 4/296:00 am
STI
- COS
2 stops16h 20m
Delta
Deal found 2/2![Delta logo]()
$455
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:15 am
COS
- STI
2 stops16h 07m
Delta
Fri 5/18:59 pm
STI
- COS
2 stops28h 07m
Delta
Deal found 2/2![Delta logo]()
$455
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:50 pm
DEN
- STI
1 stop17h 30m
Delta
Thu 6/256:15 am
STI
- DEN
2 stops19h 30m
Delta
Deal found 2/1![Delta logo]()
$583
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/812:35 am
DEN
- STI
2 stops16h 40m
Delta
Wed 4/156:00 am
STI
- DEN
2 stops15h 05m
Delta
Deal found 2/1![Delta logo]()
$587
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:40 am
DEN
- STI
1 stop10h 35m
Delta
Sat 4/46:00 am
STI
- DEN
1 stop15h 36m
Delta
Deal found 2/2![Delta logo]()
$587
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2711:55 pm
DEN
- STI
1 stop17h 20m
Delta
Sat 4/46:00 am
STI
- DEN
1 stop15h 36m
Delta
Deal found 2/2![Delta logo]()
$587
Last-minute flights from Colorado to Santiago de los CaballerosDiscover last-minute flight deals from Colorado to Santiago de los Caballeros. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Colorado to Santiago de los Caballeros. Data last updated February 3, 2026 and is based on user searches.
This KAYAK deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/611:40 am
DEN
- STI
1 stop12h 13m
JetBlue
Mon 2/1611:09 pm
STI
- DEN
1 stop13h 37m
JetBlue
Deal found 2/2![JetBlue logo]()
$542
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:40 am
DEN
- STI
1 stop15h 10m
Delta
Mon 2/166:39 am
STI
- DEN
1 stop18h 42m
Delta
Deal found 2/1![Delta logo]()
$587
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:59 pm
DEN
- STI
1 stop12h 36m
JetBlue
Wed 3/118:29 am
STI
- DEN
2 stops15h 49m
JetBlue
Deal found 2/2![JetBlue logo]()
$440
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:59 pm
DEN
- STI
2 stops18h 31m
American Airlines
Wed 3/117:00 am
STI
- DEN
2 stops14h 04m
American Airlines
Deal found 2/2![American Airlines logo]()
$583
This Orbitz deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2710:59 pm
DEN
- STI
2 stops30h 17m
Multiple Airlines
Sun 4/511:40 am
STI
- DEN
1 stop13h 13m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$606
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2711:59 pm
DEN
- STI
2 stops18h 30m
American Airlines
Sun 4/51:30 pm
STI
- DEN
2 stops20h 50m
American Airlines
Deal found 2/2![American Airlines logo]()
$651
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:14 pm
DEN
- STI
2 stops30h 35m
Multiple Airlines
Sun 4/511:40 am
STI
- DEN
1 stop13h 13m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$609
Find flight deals from Colorado to Santiago de los Caballeros
Keep the following information in mind while searching for Colorado to Santiago de los Caballeros flight deals. Data was last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $399 (Delta) |
Popular in | December |
Cheapest in | October |
Average price | $542 |
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Colorado to Santiago de los Caballeros that are best for you.
Fly from
Colorado
Fly to
Santiago de los Caballeros
Route
Depart
Return
Price
Colorado SpringsSantiago de los Caballeros
COS - STI
COSSTI
Colorado Springs
Tue 4/14
6:15 am-12:22 am
2 stops16h 07m
Santiago de los Caballeros
Mon 4/27
8:59 pm-12:17 pm
2 stops17h 18m
$399
Colorado SpringsSantiago de los Caballeros
COS - STI
COSSTI
Colorado Springs
Wed 4/15
1:39 pm-12:23 pm
2 stops20h 44m
Santiago de los Caballeros
Wed 4/29
1:32 pm-4:23 pm
2 stops28h 51m
$415
DenverSantiago de los Caballeros
DEN - STI
DENSTI
Denver Intl
Thu 4/9
11:59 pm-1:48 pm
1 stop11h 49m
Santiago de los Caballeros
Tue 4/14
3:34 am-3:30 pm
1 stop13h 56m
$426
DenverSantiago de los Caballeros
DEN - STI
DENSTI
Denver Intl
Thu 3/5
11:59 pm-3:35 pm
1 stop12h 36m
Santiago de los Caballeros
Wed 3/11
8:29 am-10:18 pm
2 stops15h 49m
$440
Colorado SpringsSantiago de los Caballeros
COS - STI
COSSTI
Colorado Springs
Wed 4/15
1:13 pm-12:10 pm
2 stops20h 57m
Santiago de los Caballeros
Sat 5/2
6:00 am-11:12 am
2 stops31h 12m
$455
Colorado SpringsSantiago de los Caballeros
COS - STI
COSSTI
Colorado Springs
Tue 4/14
11:55 am-7:33 pm
2 stops29h 38m
Santiago de los Caballeros
Sat 5/2
6:00 am-11:12 am
2 stops31h 12m
$455
Colorado SpringsSantiago de los Caballeros
COS - STI
COSSTI
Colorado Springs
Mon 4/13
6:15 am-12:22 am
2 stops16h 07m
Santiago de los Caballeros
Mon 4/27
8:59 pm-12:17 pm
2 stops17h 18m
$455
Colorado SpringsSantiago de los Caballeros
COS - STI
COSSTI
Colorado Springs
Wed 4/15
6:15 am-12:10 pm
2 stops27h 55m
Santiago de los Caballeros
Fri 5/1
8:59 pm-11:06 pm
2 stops28h 07m
$455
Colorado SpringsSantiago de los Caballeros
COS - STI
COSSTI
Colorado Springs
Sat 4/18
11:55 am-7:33 pm
2 stops29h 38m
Santiago de los Caballeros
Mon 4/27
8:59 pm-12:17 pm
2 stops17h 18m
$455
Colorado SpringsSantiago de los Caballeros
COS - STI
COSSTI
Colorado Springs
Tue 4/14
11:55 am-7:33 pm
2 stops29h 38m
Santiago de los Caballeros
Wed 4/29
6:00 am-8:20 pm
2 stops16h 20m
$455
Showing 1-10 of 19 results
Best time to book a flight from Colorado to Santiago de los Caballeros
Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Colorado with our price prediction graph.
DEN-STI
COS-STI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to Santiago de los Caballeros
USCO-STI
DEN-STI
COS-STI
What is the cheapest month to book a flight from Colorado to Santiago de los Caballeros?
Currently, October is the cheapest month in which you can book a flight from Colorado to Santiago de los Caballeros (average of $253). Flying from Colorado to Santiago de los Caballeros in August is currently the most expensive (average of $522). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Colorado to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Colorado to Santiago de los Caballeros
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Complete your trip
Complete your trip to Santiago de los Caballeros by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Colorado to Santiago de los Caballeros, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Colorado and Santiago de los Caballeros flights
Browse other Colorado and Santiago de los Caballeros flight options. Last updated on February 3, 2026.
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Other flights to Santiago de los Caballeros
Explore flights to Santiago de los Caballeros departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 3, 2026.
Colorado to Santiago de los Caballeros flights
Consider these flights traveling from Colorado to Santiago de los Caballeros.
Top 2 airlines flying from Colorado to Santiago de los Caballeros
Discover the top 2 airlines that operate flights from Colorado to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$244 | Average$549 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$413 | Average$643 | FlexibilityNo cancel fee | On-time71% |