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Santiago de los Caballeros

$315+ Cheap flights from Charleston (CHS) to Santiago de los Caballeros (STI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STI
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Charleston to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 18, 2025.

Round-trip from

$315
(FlightHub)

Popular in

December

Cheapest in

February

Average price

$758
From Charleston to Santiago de los Caballeros
Search Deals
Highest demand for flights based on searches. 43% potential increase in price ($503 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($57 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Charleston to Santiago de los Caballeros

Cheapest flights from Charleston to Santiago de los Caballeros
Explore the most affordable flight options available from Charleston to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/510:31 amCHS - STI
1 stop24h 37mSpirit Airlines
Sat 10/2512:13 pmSTI - CHS
1 stop21h 13mSpirit Airlines
Deal found 8/17$315
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:00 amCHS - STI
1 stop6h 40mDelta
Fri 9/266:11 amSTI - CHS
1 stop16h 05mDelta
Deal found 8/17$429
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:00 amCHS - STI
1 stop13h 06mDelta
Tue 11/186:45 amSTI - CHS
1 stop15h 06mDelta
Deal found 8/16$431
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/225:38 amCHS - STI
1 stop15h 10mAmerican Airlines
Fri 8/291:31 pmSTI - CHS
1 stop10h 52mAmerican Airlines
Deal found 8/17$459
This Expedia deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/59:40 amCHS - STI
2 stops27h 10mJetBlue
Fri 10/243:20 amSTI - CHS
1 stop14h 45mJetBlue
Deal found 8/17$537
This JetBlue deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1611:10 amCHS - STI
1 stop6h 54mJetBlue
Thu 9/253:20 amSTI - CHS
1 stop14h 25mJetBlue
Deal found 8/17$626

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Charleston to Santiago de los Caballeros that are best for you.

Fly from

Charleston

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sun 10/5

10:31 am-11:08 am

1 stop24h 37m

Santiago de los Caballeros

Sat 10/25

12:13 pm-9:26 am

1 stop21h 13m

$315

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Fri 9/19

6:00 am-7:11 pm

1 stop13h 11m

Santiago de los Caballeros

Mon 9/29

8:40 pm-12:07 pm

1 stop15h 27m

$429

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Fri 10/3

12:51 pm-12:34 am

1 stop11h 43m

Santiago de los Caballeros

Mon 10/6

6:00 am-5:51 pm

1 stop11h 51m

$429

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 9/16

6:00 am-12:40 pm

1 stop6h 40m

Santiago de los Caballeros

Fri 9/26

6:11 am-10:16 pm

1 stop16h 05m

$429

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 11/5

6:15 am-3:38 pm

1 stop8h 23m

Santiago de los Caballeros

Mon 11/17

4:41 am-1:19 pm

1 stop9h 38m

$431

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sat 1/10

9:37 am-9:24 pm

1 stop10h 47m

Santiago de los Caballeros

Sat 1/17

4:35 pm-11:12 pm

1 stop7h 37m

$431

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 11/5

6:00 am-8:06 pm

1 stop13h 06m

Santiago de los Caballeros

Tue 11/18

6:45 am-8:51 pm

1 stop15h 06m

$431

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Fri 9/19

7:28 pm-12:27 pm

2 stops16h 59m

Santiago de los Caballeros

Mon 9/29

1:29 pm-10:24 am

2 stops20h 55m

$433

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sun 10/5

6:38 pm-12:13 pm

2 stops17h 35m

Santiago de los Caballeros

Sat 10/25

1:14 pm-10:26 am

2 stops21h 12m

$433

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Best time to book a flight from Charleston to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santiago de los Caballeros

What is the cheapest month to book a flight from Charleston to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Charleston to Santiago de los Caballeros (average of $347). Flying from Charleston to Santiago de los Caballeros in July is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated August 18, 2025.
Read through reviews of airlines operating flights from Charleston to Santiago de los Caballeros, such as American Airlines and JetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Overall

7.2

Food

6.5

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Overall

7.2

Food

6.5

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
JetBlue
7.2
Good
2,915 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Overall

7.2

Food

6.5

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Santiago de los Caballeros?

    A quick flight from Charleston to Santiago de los Caballeros can take about 13h 11m. Spirit Airlines provides one of the quickest options available for as low as $429. The distance from Charleston to Santiago de los Caballeros is about 1098 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Charleston to Santiago de los Caballeros round-trip?

    Currently priced at $371, JetBlue will fly you from Charleston to Santiago de los Caballeros and back. In addition to JetBlue, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $500. JetBlue is 42% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Charleston to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Charleston to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santiago de los Caballeros.

  • Can I find deals for business class flights from Charleston to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Charleston to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from Charleston to Santiago de los Caballeros (average of $347). Flying from Charleston to Santiago de los Caballeros in July is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Charleston to Santiago de los Caballeros

Discover the top 2 airlines that operate flights from Charleston to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$371Average$565FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$500Average$775FlexibilityNo cancel feeOn-time71%

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