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Cheap flights from Santo Domingo (SDQ) to Santiago (SCL)

SDQ — SCL
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
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Find flight deals from Santo Domingo to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$625
(Kiwi.com)

One-way from

$259
(Trip.com)

Popular in

January

Cheapest in

October

Average price

$780
Provider with most accurate pricing for Santo Domingo Las Americas-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Santiago Arturo Merino Benitez flights.
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From Santo Domingo Las Americas to Santiago Arturo Merino Benitez
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One-way flight from Santo Domingo Las Americas to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 17% potential increase in price ($136 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in February 2026
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  • Most accurate provider: When it comes to deals on Santo Domingo-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Santiago

How far ahead should I book a flight from Santo Domingo to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Santiago. Price data was last updated on February 6, 2026.

The best time to book flights from Santo Domingo to Santiago is 67 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santo Domingo to Santiago?

Currently, September is the cheapest month in which you can book a flight from Santo Domingo to Santiago (average of $239). Flying from Santo Domingo to Santiago in January is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santo Domingo to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated February 13, 2026.
Get a feel of what it's like to fly with Copa Airlines and Avianca from Santo Domingo to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,559 reviews

Comfort

7.4

Overall

7.5

Crew

8.1

Entertainment

6.8

Food

6.8

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
Copa Airlines
7.5
Good
1,559 reviews
Copa Airlines
7.5
Good
1,559 reviews

Comfort

7.4

Overall

7.5

Crew

8.1

Entertainment

6.8

Food

6.8

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
Avianca
6.5
Okay
2,495 reviews
Copa Airlines
7.5
Good
1,559 reviews

Comfort

7.4

Overall

7.5

Crew

8.1

Entertainment

6.8

Food

6.8

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Santiago?

    There are many flights that can get you from Santo Domingo to Santiago in 10h 45m. Fly via Avianca to get the fastest option. The distance between Santo Domingo and Santiago is about 3579 mi.

  • What are the cheapest airlines flying from Santo Domingo to Santiago round-trip?

    According to our current data, Copa Airlines ($281), and Avianca ($321) offers the cheapest pricing from Santo Domingo to Santiago. Copa Airlines is 56% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santo Domingo to Santiago that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Santiago.

  • Can I find deals for business class flights from Santo Domingo to Santiago?

    Yes. Cheapflights offers flight deals from Santo Domingo to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Santiago?

    Currently, September is the cheapest month in which you can book a flight from Santo Domingo to Santiago (average of $239). Flying from Santo Domingo to Santiago in January is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Santo Domingo to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Punta Cana to Santiago flights

Top 2 airlines flying from Santo Domingo to Santiago

Discover the top 2 airlines that operate flights from Santo Domingo to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$281Average$744FlexibilityNo cancel feeOn-time70%
AviancaCheapest$321Average$607FlexibilityNo cancel feeOn-time71%

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