HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$234+ Cheap flights from Santo Domingo (SDQ) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — SCL
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santo Domingo to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Santo Domingo Las Americas to Santiago Arturo Merino Benitez are usually found in October or July, booked 67 days in advance, depart on a Wednesday or Monday and return on a Monday

Cheap flight deals from Santo Domingo to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated junio 12, 2025.

Round-trip from

$473
(Arajet)

One-way from

$234
(Arajet)

Popular in

February

Cheapest in

October

Average price

$573
From Santo Domingo Las Americas to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Santo Domingo Las Americas to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($116 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Santo Domingo to Santiago

Cheapest flights from Santo Domingo to Santiago
Explore the most affordable flight options available from Santo Domingo to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Arajet deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/142:05 pmSDQ - SCL
1 stop12h 30mMultiple Airlines
dom. 8/173:35 amSCL - SDQ
1 stop11h 45mMultiple Airlines
Deal found 6/10$473
This Priceline deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/1711:45 amSDQ - SCL
1 stop10h 45mAvianca
jue. 7/246:10 amSCL - SDQ
1 stop11h 05mAvianca
Deal found 6/11$548
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/138:55 amSDQ - SCL
1 stop14h 13mCopa Airlines
sáb. 8/162:23 amSCL - SDQ
1 stop20h 04mCopa Airlines
Deal found 6/10$736
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/66:00 amSDQ - SCL
2 stops25h 50mUnited Airlines
dom. 11/1610:45 pmSCL - SDQ
2 stops26h 01mUnited Airlines
Deal found 6/10$1,982
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/56:00 amSDQ - SCL
2 stops25h 00mDelta
mar. 8/128:40 pmSCL - SDQ
1 stop16h 42mDelta
Deal found 6/10$2,524
This Iberia deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/1210:13 amSDQ - SCL
2 stops45h 07mIberia
lun. 6/167:00 pmSCL - SDQ
2 stops49h 45mIberia
Deal found 6/10$3,395
This British Airways deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/1110:15 amSDQ - SCL
2 stops45h 20mBritish Airways
dom. 7/132:55 pmSCL - SDQ
2 stops54h 00mBritish Airways
Deal found 6/9$3,483

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Santo Domingo to Santiago that are best for you.

Fly from

Santo Domingo

Fly to

Santiago

Route

Depart

Return

Price

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

jue. 8/14

2:05 pm-2:35 am

1 stop12h 30m

Santiago Arturo Merino Benitez

dom. 8/17

3:35 am-3:20 pm

1 stop11h 45m

$473

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

jue. 7/17

11:45 am-10:30 pm

1 stop10h 45m

Santiago Arturo Merino Benitez

jue. 7/24

6:10 am-5:15 pm

1 stop11h 05m

$548

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

mié. 8/13

8:55 am-11:08 pm

1 stop14h 13m

Santiago Arturo Merino Benitez

sáb. 8/16

2:23 am-10:27 pm

1 stop20h 04m

$736

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

jue. 11/6

6:00 am-8:50 am

2 stops25h 50m

Santiago Arturo Merino Benitez

dom. 11/16

10:45 pm-11:46 pm

2 stops26h 01m

$1,982

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

mar. 8/5

6:00 am-7:00 am

2 stops25h 00m

Santiago Arturo Merino Benitez

mar. 8/12

2:10 pm-1:22 pm

2 stops23h 12m

$2,524

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

vie. 7/11

10:15 am-7:35 am

2 stops45h 20m

Santiago Arturo Merino Benitez

dom. 7/13

2:55 pm-8:55 pm

2 stops54h 00m

$3,483

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

jue. 7/3

10:13 am-7:20 am

2 stops45h 07m

Santiago Arturo Merino Benitez

jue. 7/10

7:00 pm-8:55 pm

2 stops49h 55m

$3,614

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

jue. 8/14

2:05 pm-2:35 am

1 stop12h 30m

$234

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

mar. 6/17

6:10 pm-4:35 am

1 stop10h 25m

$278

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

lun. 6/23

10:13 am-7:20 am

2 stops45h 07m

$1,696

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 11 results
1
2

Best time to book a flight from Santo Domingo to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Santiago

How far ahead should I book a flight from Santo Domingo to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Santiago. Price data was last updated on June 9, 2025.

The best time to book flights from Santo Domingo to Santiago is 67 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santo Domingo to Santiago?

Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Santiago (average of $752). Flying from Santo Domingo to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to SCL?

Find hourly flight availability from Santo Domingo to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Santo Domingo to Santiago at noon. If you’re flexible enough to do this you can expect to save up to 18% on your trip compared to booking a flight in the morning.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated junio 12, 2025.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Anonymous,Sep 2023

LGA - SYR

No A/C bad landing by pilot kinda scary. Not because of weather
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Anonymous,Sep 2023

LGA - SYR

No A/C bad landing by pilot kinda scary. Not because of weather
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Anonymous,Sep 2023

LGA - SYR

No A/C bad landing by pilot kinda scary. Not because of weather
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Anonymous,Sep 2023

LGA - SYR

No A/C bad landing by pilot kinda scary. Not because of weather
Iberia
7.0
Good
2,776 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Anonymous,Sep 2023

LGA - SYR

No A/C bad landing by pilot kinda scary. Not because of weather
Avianca
6.7
Okay
2,345 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Anonymous,Sep 2023

LGA - SYR

No A/C bad landing by pilot kinda scary. Not because of weather

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santo Domingo to Santiago round-trip?

    According to our current data, Avianca ($548), Copa Airlines ($736), and United Airlines ($1,982) offers the cheapest pricing from Santo Domingo to Santiago. Avianca is 9% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Santo Domingo to Santiago one-way?

    For one-way options, check prices for Avianca. According to our data, you can fly for as low as $278. Users have also found prices from $1,696 and $14,353 on Iberia and Delta, respectively.

  • Can I find deals for flights from Santo Domingo to Santiago that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Santiago.

  • Can I find deals for business class flights from Santo Domingo to Santiago?

    Yes. Cheapflights offers flight deals from Santo Domingo to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Santiago (average of $752). Flying from Santo Domingo to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santo Domingo to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Punta Cana to Santiago flights

Top 2 airlines flying from Santo Domingo to Santiago

Discover the top 2 airlines that operate flights from Santo Domingo to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$348Average$566FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$437Average$656FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.