$301+ Cheap flights from Santiago (SCL) to Santo Domingo (SDQ)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SDQ
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santiago to Santo Domingo
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One-way
Cheapest flights from Santiago to Santo DomingoExplore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:10 am -
1 stop10h 40m
Sun 11/1512:45 pm -
1 stop11h 20m
Deal found 10/28![Avianca logo]()
$560
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:30 am -
1 stop11h 20m
Mon 11/2312:45 pm -
1 stop16h 00m
Deal found 10/28![Avianca logo]()
$569
This FlightHub deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:15 pm -
1 stop26h 35m
Thu 12/1712:45 pm -
1 stop25h 25m
Deal found 10/28![Avianca logo]()
$572
This Copa Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:07 am -
1 stop22h 51m
Thu 1/78:52 am -
1 stop20h 05m
Deal found 10/29![Copa Airlines logo]()
$574
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:48 am -
1 stop10h 22m
Sat 12/52:14 pm -
1 stop12h 29m
Deal found 10/29![Copa Airlines logo]()
$582
This Arajet deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:00 am -
1 stop12h 20m
Thu 1/72:05 pm -
1 stop12h 30m
Deal found 10/25![Multiple Airlines logo]()
$594
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/141:07 am -
1 stop10h 55m
Tue 12/152:14 pm -
1 stop12h 29m
Deal found 10/30![Copa Airlines logo]()
$597
This Justfly.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:30 am -
1 stop29h 20m
Mon 11/166:45 pm -
1 stop29h 20m
Deal found 10/28![Avianca logo]()
$603
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:10 am -
1 stop16h 40m
Sat 11/2112:45 pm -
1 stop11h 20m
Deal found 10/29![Avianca logo]()
$608
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/221:07 am -
1 stop22h 51m
Sun 1/317:05 pm -
1 stop27h 36m
Deal found 10/30![Copa Airlines logo]()
$620
This FlightHub deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:15 pm -
1 stop26h 35m
Fri 11/2012:45 pm -
1 stop11h 20m
Deal found 10/29![Avianca logo]()
$626
Best flights from Santiago to Santo DomingoDiscover carefully curated flight deals from Santiago to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Santiago to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:07 am -
1 stop18h 51m
Thu 12/1012:43 pm -
1 stop16h 09m
Deal found 10/28![Copa Airlines logo]()
$574
This Copa Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:07 am -
1 stop22h 01m
Fri 12/1112:43 pm -
1 stop13h 05m
Deal found 10/29![Copa Airlines logo]()
$574
This Copa Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/812:20 pm -
1 stop28h 53m
Sun 12/137:03 pm -
1 stop24h 08m
Deal found 10/29![Copa Airlines logo]()
$574
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/281:31 am -
1 stop11h 11m
Mon 1/1112:42 pm -
1 stop13h 11m
Deal found 10/30![Copa Airlines logo]()
$597
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:15 pm -
1 stop28h 57m
Thu 11/192:20 pm -
1 stop12h 18m
Deal found 10/28![Copa Airlines logo]()
$597
This Copa Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/121:07 am -
1 stop11h 35m
Tue 1/58:52 am -
1 stop20h 05m
Deal found 10/29![Copa Airlines logo]()
$597
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/141:07 am -
1 stop10h 55m
Tue 12/152:14 pm -
1 stop12h 29m
Deal found 10/30![Copa Airlines logo]()
$597
This Copa Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:07 am -
1 stop22h 01m
Wed 1/1312:42 pm -
1 stop16h 15m
Deal found 10/27![Copa Airlines logo]()
$620
Last-minute flights from Santiago to Santo DomingoDiscover last-minute flight deals from Santiago to Santo Domingo. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to Santo Domingo. Data last updated October 30, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:30 am -
1 stop11h 20m
Sat 11/76:45 pm -
1 stop10h 00m
Deal found 10/29![Avianca logo]()
$682
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:10 am -
1 stop10h 40m
Sun 11/1512:45 pm -
1 stop11h 20m
Deal found 10/28![Avianca logo]()
$560
This Justfly.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:30 am -
1 stop29h 20m
Mon 11/166:45 pm -
1 stop29h 20m
Deal found 10/28![Avianca logo]()
$603
This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:15 pm -
1 stop20h 35m
Tue 11/1712:45 pm -
1 stop16h 00m
Deal found 10/26![Avianca logo]()
$651
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:10 am -
1 stop16h 40m
Sat 11/2112:45 pm -
1 stop11h 20m
Deal found 10/29![Avianca logo]()
$608
This FlightHub deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:15 pm -
1 stop26h 35m
Fri 11/2012:45 pm -
1 stop11h 20m
Deal found 10/29![Avianca logo]()
$626
This Avianca deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/152:10 am -
1 stop10h 40m
Mon 11/166:45 pm -
1 stop10h 00m
Deal found 10/25![Avianca logo]()
$633
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:30 am -
1 stop11h 20m
Mon 11/2312:45 pm -
1 stop16h 00m
Deal found 10/28![Avianca logo]()
$569
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2712:15 pm -
1 stop24h 30m
Fri 12/47:03 pm -
1 stop24h 08m
Deal found 10/28![Copa Airlines logo]()
$574
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:48 am -
1 stop10h 22m
Sat 12/52:14 pm -
1 stop12h 29m
Deal found 10/29![Copa Airlines logo]()
$582
This Copa Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/281:26 am -
1 stop22h 32m
Sun 12/612:43 pm -
1 stop10h 40m
Deal found 10/29![Copa Airlines logo]()
$597
One-way flights from Santiago to Santo DomingoSearch for one-way flight options from Santiago to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Santiago to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:30 am -
1 stop11h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Avianca logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1511:03 am -
2 stops21h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$313
This Arajet deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:25 am -
1 stop13h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$327
This Trip.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/305:56 am -
1 stop27h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$328
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:30 am -
1 stop11h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Avianca logo]()
$331
This Gotogate deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:15 pm -
1 stop26h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Avianca logo]()
$332
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/252:10 am -
1 stop16h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Avianca logo]()
$333
This FlightHub deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:15 pm -
1 stop26h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Avianca logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1910:12 pm -
1 stop33h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/2610:12 pm -
1 stop33h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:07 am -
1 stop26h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$345
Find flight deals from Santiago to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $539 (Avianca) |
One-way from | $301 (Avianca) |
Popular in | January |
Cheapest in | November |
Average price | $614 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Tue 11/10
7:30 am-11:50 am
1 stop29h 20m
Santo Domingo Las Americas
Wed 12/31
12:00 am-1:30 am
Nonstop0h 00m
$323
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Mon 11/23
6:00 am-4:45 pm
1 stop11h 45m
Santo Domingo Las Americas
Wed 12/31
12:00 am-1:30 am
Nonstop0h 00m
$347
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Fri 11/6
12:15 pm-1:10 pm
1 stop25h 55m
Santo Domingo Las Americas
Wed 12/31
12:00 am-1:30 am
Nonstop0h 00m
$368
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Mon 11/23
12:15 pm-1:10 pm
1 stop25h 55m
Santo Domingo Las Americas
Wed 12/31
12:00 am-1:30 am
Nonstop0h 00m
$368
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Thu 11/19
5:07 am-10:58 pm
1 stop18h 51m
Santo Domingo Las Americas
Wed 12/31
12:00 am-1:30 am
Nonstop0h 00m
$368
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Sun 12/13
12:20 pm-10:58 pm
1 stop11h 38m
Santo Domingo Las Americas
Wed 12/31
12:00 am-1:30 am
Nonstop0h 00m
$368
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Fri 11/27
12:15 pm-11:45 am
1 stop24h 30m
Santo Domingo Las Americas
Wed 12/31
12:00 am-1:30 am
Nonstop0h 00m
$368
Quickest round-trip
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Wed 11/25
1:26 am-11:07 am
1 stop10h 41m
Santo Domingo Las Americas
Wed 12/31
12:00 am-1:30 am
Nonstop0h 00m
$368
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Sat 11/14
1:02 am-10:58 pm
1 stop22h 56m
Santo Domingo Las Americas
Wed 12/31
12:00 am-1:30 am
Nonstop0h 00m
$391
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Mon 12/14
3:48 am-10:58 pm
1 stop20h 10m
Santo Domingo Las Americas
Wed 12/31
12:00 am-1:30 am
Nonstop0h 00m
$391
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Santiago to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Santo Domingo in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santiago-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Santiago with our price prediction graph.
SCL-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Santo Domingo
How far ahead should I book a flight from Santiago to Santo Domingo?
Booking 66 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Santo Domingo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Santiago to Santo Domingo?
Currently, November is the cheapest month in which you can book a flight from Santiago to Santo Domingo (average of $565). Flying from Santiago to Santo Domingo in January is currently the most expensive (average of $710). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to Santo Domingo?
Airfare is typical for this route at the moment.
Santiago to Santo Domingo flights typically cost between $508 and $602 in February.The cheapest round-trip price found within the last 5 days was $539 on Avianca (Feb 23-Mar 2).
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated October 30, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Santiago to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Entertainment
6.9
Overall
7.6
Boarding
7.8
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Food
7.0
Entertainment
6.9
Overall
7.6
Boarding
7.8
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Food
7.0
Entertainment
6.9
Overall
7.6
Boarding
7.8
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Santiago to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Top 2 airlines flying from Santiago to Santo Domingo
Discover the top 2 airlines that operate flights from Santiago to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$536 | Average$886 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$545 | Average$629 | FlexibilityNo cancel fee | On-time70% |