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Santo Domingo

$292+ Cheap flights from Santiago (SCL) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SDQ
May 15 — May 221
Fri 5/15
Fri 5/22
1 adult, Economy
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Cheap flight deals from Santiago to Santo Domingo

Cheapest flights from Santiago to Santo Domingo
Explore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2026.

This Arajet deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:00 am
SCL
-
SDQ
1 stop11h 55m
Multiple Airlines
Fri 5/298:55 am
SDQ
-
SCL
1 stop14h 00m
Multiple Airlines
Deal found 4/15$464
This Arajet deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:00 am
SCL
-
SDQ
1 stop11h 55m
Multiple Airlines
Tue 7/141:45 pm
SDQ
-
SCL
1 stop12h 50m
Multiple Airlines
Deal found 4/15$474
This Arajet deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:35 am
SCL
-
SDQ
1 stop12h 10m
Multiple Airlines
Fri 6/58:55 am
SDQ
-
SCL
1 stop14h 00m
Multiple Airlines
Deal found 4/14$503
This Arajet deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:35 am
SCL
-
SDQ
1 stop12h 20m
Multiple Airlines
Tue 5/121:45 pm
SDQ
-
SCL
1 stop12h 50m
Multiple Airlines
Deal found 4/11$576
This Arajet deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:00 am
SCL
-
SDQ
1 stop11h 55m
Multiple Airlines
Fri 6/128:55 am
SDQ
-
SCL
1 stop14h 00m
Multiple Airlines
Deal found 4/12$594
This Arajet deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:35 am
SCL
-
SDQ
1 stop12h 10m
Multiple Airlines
Fri 5/298:55 am
SDQ
-
SCL
1 stop14h 00m
Multiple Airlines
Deal found 4/13$595
This Arajet deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:35 am
SCL
-
SDQ
1 stop12h 10m
Multiple Airlines
Sun 8/163:25 pm
SDQ
-
SCL
1 stop12h 30m
Multiple Airlines
Deal found 4/13$615
This Avianca deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/121:30 am
SCL
-
SDQ
1 stop11h 20m
Avianca
Sun 10/186:50 pm
SDQ
-
SCL
1 stop9h 55m
Avianca
Deal found 4/14$637
This Avianca deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:30 am
SCL
-
SDQ
1 stop11h 20m
Avianca
Thu 5/216:50 pm
SDQ
-
SCL
1 stop9h 55m
Avianca
Deal found 4/15$648

Find flight deals from Santiago to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$464
(Arajet)

One-way from

$292
(Trip.com)

Popular in

January

Cheapest in

August

Average price

$575

Good one-way deal

$261 or less
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Santo Domingo Las Americas flights.
Search Deals
From Santiago Arturo Merino Benitez to Santo Domingo Las Americas
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($89 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Santo Domingo Las Americas.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2026.
Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 8/3

5:00 am-4:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Sun 8/16

3:25 pm-3:55 am

1 stop12h 30m

$464

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 8/10

5:00 am-4:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Thu 8/20

1:45 pm-2:35 am

1 stop12h 50m

$474

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 5/28

3:35 am-3:45 pm

1 stop12h 10m

Santo Domingo Las Americas

Fri 6/5

8:55 am-10:55 pm

1 stop14h 00m

$562

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sun 7/19

2:27 am-10:56 pm

1 stop20h 29m

Santo Domingo Las Americas

Fri 7/31

2:17 pm-3:00 am

1 stop12h 43m

$660

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 10/6

1:44 am-10:54 am

1 stop10h 10m

Santo Domingo Las Americas

Wed 10/7

2:16 pm-3:16 am

1 stop12h 00m

$660

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 8/4

12:06 am-1:13 pm

1 stop13h 07m

Santo Domingo Las Americas

Sun 8/9

6:07 am-10:43 pm

1 stop16h 36m

$660

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 8/3

2:56 am-10:56 pm

1 stop20h 00m

Santo Domingo Las Americas

Sun 8/9

6:07 am-7:23 pm

1 stop13h 16m

$660
Quickest round-trip

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 8/3

11:22 am-10:56 pm

1 stop11h 34m

Santo Domingo Las Americas

Sat 8/8

8:48 am-7:23 pm

1 stop10h 35m

$660
Cheapest one-way

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 7/2

3:35 am-3:45 pm

1 stop12h 10m

$312

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 10/6

7:40 am-5:55 pm

1 stop11h 15m

$326

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/11

Showing 1-10 of 15 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Santiago-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Santo Domingo

How far ahead should I book a flight from Santiago to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Santo Domingo. Price data was last updated on April 10, 2026.

Booking 42 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Santo Domingo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to Santo Domingo?

Currently, October is the cheapest month in which you can book a flight from Santiago to Santo Domingo (average of $253). Flying from Santiago to Santo Domingo in April is currently the most expensive (average of $509). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santiago to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated April 15, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Santiago to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,575 reviews

Comfort

7.4

Food

6.8

Overall

7.5

Crew

8.1

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,575 reviews
Copa Airlines
7.5
Good
1,575 reviews

Comfort

7.4

Food

6.8

Overall

7.5

Crew

8.1

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Avianca
6.5
Okay
2,509 reviews
Copa Airlines
7.5
Good
1,575 reviews

Comfort

7.4

Food

6.8

Overall

7.5

Crew

8.1

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Santo Domingo?

    Departing from Santiago to Santo Domingo will take you 12h 30m. There are 3579 mi between Santiago and Santo Domingo.

  • What are the cheapest airlines flying from Santiago to Santo Domingo round-trip?

    Flying on Avianca is currently your cheapest option to Santo Domingo, with prices starting at $502. Another option worth looking into is Copa Airlines, starting at $515 round trip. Avianca is 13% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Santiago to Santo Domingo?

    The cheapest flight price from Santiago to Santo Domingo is $261. On average you can expect to pay $261. The most popular route, (Santiago Arturo Merino Benitez - Santo Domingo Las Americas), can usually be booked for $649.

  • Can I find deals for flights from Santiago to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Santiago to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Santo Domingo.

  • Can I find deals for business class flights from Santiago to Santo Domingo?

    Yes. Cheapflights offers flight deals from Santiago to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Santo Domingo?

    Currently, October is the cheapest month in which you can book a flight from Santiago to Santo Domingo (average of $253). Flying from Santiago to Santo Domingo in April is currently the most expensive (average of $509). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Santiago to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
Santiago to Punta Cana flights

Top 2 airlines flying from Santiago to Santo Domingo

Discover the top 2 airlines that operate flights from Santiago to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$502Average$587FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$515Average$613FlexibilityNo cancel feeOn-time70%

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