$250+ Cheap flights from Santiago (SCL) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SDQ
Sep 3 — Sep 101
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santiago to Santo Domingo
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Cheapest flights from Santiago to Santo DomingoExplore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 4, 2026.
Explore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 4, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3112:43 am -
1 stop12h 30m
Wed 9/238:47 am -
1 stop20h 23m
Deal found 8/1![Copa Airlines logo]()
$574
This Arajet deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/199:25 am -
1 stop13h 15m
Sun 1/103:55 pm -
1 stop12h 00m
Deal found 8/2![Multiple Airlines logo]()
$586
This Arajet deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:00 am -
1 stop12h 20m
Tue 2/231:40 pm -
1 stop12h 55m
Deal found 7/31![Multiple Airlines logo]()
$617
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:06 am -
1 stop10h 49m
Sat 9/52:16 pm -
1 stop14h 54m
Deal found 7/31![Copa Airlines logo]()
$620
This Avianca deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:30 am -
1 stop11h 20m
Fri 9/412:45 pm -
1 stop10h 35m
Deal found 8/1![Avianca logo]()
$624
This Arajet deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/199:25 am -
1 stop13h 15m
Sat 1/91:40 pm -
1 stop12h 10m
Deal found 7/30![Multiple Airlines logo]()
$626
This Copa Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:48 am -
1 stop10h 26m
Thu 12/178:55 am -
1 stop14h 23m
Deal found 7/30![Copa Airlines logo]()
$627
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:40 am -
1 stop11h 15m
Thu 9/249:00 pm -
2 stops17h 00m
Deal found 7/30![Multiple Airlines logo]()
$638
This Copa Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:19 am -
1 stop13h 54m
Thu 1/77:05 pm -
1 stop9h 52m
Deal found 7/30![Copa Airlines logo]()
$650
This Avianca deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:25 am -
1 stop10h 25m
Mon 1/1112:45 pm -
1 stop15h 45m
Deal found 7/31![Avianca logo]()
$657
This Copa Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:57 am -
1 stop10h 15m
Sat 10/1012:12 pm -
1 stop14h 44m
Deal found 7/30![Copa Airlines logo]()
$658
Best flights from Santiago to Santo DomingoDiscover carefully curated flight deals from Santiago to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 4, 2026.
Discover carefully curated flight deals from Santiago to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 4, 2026.
This Copa Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:15 am -
1 stop10h 57m
Wed 10/2812:48 pm -
1 stop13h 54m
Deal found 7/30![Copa Airlines logo]()
$574
This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:40 am -
1 stop11h 15m
Sat 9/267:20 am -
3 stops44h 57m
Deal found 7/31![Multiple Airlines logo]()
$702
This Copa Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:23 pm -
1 stop23h 31m
Sat 10/246:41 pm -
1 stop28h 41m
Deal found 8/3![Copa Airlines logo]()
$574
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3112:43 am -
1 stop12h 30m
Wed 9/238:47 am -
1 stop20h 23m
Deal found 8/1![Copa Airlines logo]()
$574
This Copa Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:06 am -
1 stop13h 07m
Sun 8/166:42 pm -
1 stop28h 01m
Deal found 8/2![Copa Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:45 pm -
2 stops41h 21m
Mon 11/24:18 pm -
2 stops63h 32m
Deal found 7/30![United Airlines logo]()
$1,856
This Copa Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:14 am -
1 stop12h 01m
Sun 9/206:41 pm -
1 stop24h 51m
Deal found 7/30![Copa Airlines logo]()
$757
Last-minute flights from Santiago to Santo DomingoDiscover last-minute flight deals from Santiago to Santo Domingo. Data last updated August 4, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to Santo Domingo. Data last updated August 4, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/212:43 am -
1 stop10h 59m
Wed 9/28:47 am -
1 stop20h 23m
Deal found 8/1![Copa Airlines logo]()
$703
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/811:22 am -
1 stop24h 20m
Sun 8/166:42 pm -
1 stop28h 44m
Deal found 7/31![Copa Airlines logo]()
$680
This Copa Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:06 am -
1 stop13h 07m
Sun 8/166:42 pm -
1 stop28h 01m
Deal found 8/3![Copa Airlines logo]()
$700
This Avianca deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:30 am -
1 stop11h 20m
Fri 9/412:45 pm -
1 stop10h 35m
Deal found 8/1![Avianca logo]()
$624
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3112:43 am -
1 stop12h 30m
Wed 9/238:47 am -
1 stop20h 23m
Deal found 8/1![Copa Airlines logo]()
$574
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:06 am -
1 stop10h 49m
Sat 9/52:16 pm -
1 stop14h 54m
Deal found 7/31![Copa Airlines logo]()
$620
This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:20 pm -
1 stop26h 35m
Sat 9/267:45 am -
2 stops20h 23m
Deal found 7/31![Multiple Airlines logo]()
$691
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:06 am -
1 stop10h 49m
Thu 9/176:06 am -
1 stop13h 26m
Deal found 7/31![Copa Airlines logo]()
$681
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:56 am -
1 stop10h 17m
Fri 9/188:47 am -
1 stop10h 45m
Deal found 8/1![Copa Airlines logo]()
$704
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:40 am -
1 stop11h 15m
Thu 9/249:00 pm -
2 stops17h 00m
Deal found 7/30![Multiple Airlines logo]()
$638
One-way flights from Santiago to Santo DomingoSearch for one-way flight options from Santiago to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated August 4, 2026.
Search for one-way flight options from Santiago to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated August 4, 2026.
This Arajet deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:00 am -
1 stop11h 55m
Deal found 7/31![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:01 am -
1 stop27h 44m
Deal found 7/31![Multiple Airlines logo]()
$288
This Avianca deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:25 am -
1 stop29h 25m
Deal found 7/30![Avianca logo]()
$312
This Avianca deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:40 am -
1 stop11h 15m
Deal found 7/31![Avianca logo]()
$331
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1511:22 am -
1 stop15h 03m
Deal found 7/31![Copa Airlines logo]()
$343
This Copa Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:43 am -
1 stop12h 30m
Deal found 8/3![Copa Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:40 pm -
2 stops56h 17m
Deal found 7/31![Multiple Airlines logo]()
$395
This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:35 am -
2 stops17h 20m
Deal found 7/31![Multiple Airlines logo]()
$425
Find flight deals from Santiago to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $574 (Copa Airlines) |
One-way from | $250 (Arajet) |
Popular in | January |
Cheapest in | October |
Average price | $663 |
Good one-way deal | $261 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
SantiagoSanto Domingo
SCL - SDQ
SCLSDQ
Santiago Arturo Merino Benitez
Tue 10/20
3:15 am-1:12 pm
1 stop10h 57m
Santo Domingo Las Americas
Wed 10/28
12:48 pm-3:42 am
1 stop13h 54m
$574
SantiagoSanto Domingo
SCL - SDQ
SCLSDQ
Santiago Arturo Merino Benitez
Mon 10/12
12:23 pm-10:54 am
1 stop23h 31m
Santo Domingo Las Americas
Sat 10/24
6:41 pm-12:22 am
1 stop28h 41m
$574
SantiagoSanto Domingo
SCL - SDQ
SCLSDQ
Santiago Arturo Merino Benitez
Mon 8/31
12:43 am-1:13 pm
1 stop12h 30m
Santo Domingo Las Americas
Wed 9/23
8:47 am-6:10 am
1 stop20h 23m
$574
SantiagoSanto Domingo
SCL - SDQ
SCLSDQ
Santiago Arturo Merino Benitez
Wed 8/12
12:06 am-1:13 pm
1 stop13h 07m
Santo Domingo Las Americas
Sun 8/16
6:42 pm-10:43 pm
1 stop28h 01m
$680
SantiagoSanto Domingo
SCL - SDQ
SCLSDQ
Santiago Arturo Merino Benitez
Fri 9/4
6:40 am-5:55 pm
1 stop11h 15m
Santo Domingo Las Americas
Sat 9/26
7:20 am-5:17 am
3 stops44h 57m
$702
SantiagoSanto Domingo
SCL - SDQ
SCLSDQ
Santiago Arturo Merino Benitez
Fri 9/11
5:14 am-4:15 pm
1 stop12h 01m
Santo Domingo Las Americas
Sun 9/20
6:41 pm-8:32 pm
1 stop24h 51m
$757
SantiagoSanto Domingo
SCL - SDQ
SCLSDQ
Santiago Arturo Merino Benitez
Thu 10/29
9:45 pm-2:06 pm
2 stops41h 21m
Santo Domingo Las Americas
Mon 11/2
4:18 pm-8:50 am
2 stops63h 32m
$1,856
Cheapest one-way
SantiagoSanto Domingo
SCL - SDQ
SCLSDQ
Santiago Arturo Merino Benitez
Wed 9/23
5:00 am-3:55 pm
1 stop11h 55m
$268
SantiagoSanto Domingo
SCL - SDQ
SCLSDQ
Santiago Arturo Merino Benitez
Mon 9/28
6:00 am-4:55 pm
1 stop11h 55m
$268
SantiagoSanto Domingo
SCL - SDQ
SCLSDQ
Santiago Arturo Merino Benitez
Sun 8/16
5:01 am-8:45 am
1 stop27h 44m
$288
Showing 1-10 of 17 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santiago-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Santiago with our price prediction graph.
SCL-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Santo Domingo
Prices
Delays
How far ahead should I book a flight from Santiago to Santo Domingo?
Booking 41 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Santo Domingo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Santiago to Santo Domingo?
Currently, October is the cheapest month in which you can book a flight from Santiago to Santo Domingo (average of $537). Flying from Santiago to Santo Domingo in January is currently the most expensive (average of $704). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to Santo Domingo?
Airfare is below average for this route at the moment.
Santiago to Santo Domingo flights typically cost between $587 and $699 in August.The cheapest round-trip price found within the last 5 days was $574 on Copa Airlines (Aug 31-Sep 23).
How often are flights from Santiago to Santo Domingo delayed?
About 100% of weekly flights between Santiago and Santo Domingo have experienced delays in the past year, with the average delay time being 411 minutes.
What is the most punctual flight time for Santiago to Santo Domingo flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated August 4, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Santiago to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Food
6.9
Entertainment
6.8
Comfort
7.4
Boarding
7.8
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Crew
8.1
Food
6.9
Entertainment
6.8
Comfort
7.4
Boarding
7.8
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Crew
8.1
Food
6.9
Entertainment
6.8
Comfort
7.4
Boarding
7.8
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Santiago to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Complete your trip
Complete your trip to Santo Domingo by adding a car rental and/or hotel reservation to your travel itinerary.
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Santiago and Santo Domingo flights
Browse other Santiago and Santo Domingo flight options. Last updated on August 4, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on August 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santo Domingo
Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 4, 2026.
Top 2 airlines flying from Santiago to Santo Domingo
Discover the top 2 airlines that operate flights from Santiago to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$517 | Average$613 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$536 | Average$719 | FlexibilityNo cancel fee | On-time71% |