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$180+ Cheap flights from Orlando Sanford Intl (SFB) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
SFB — SCL
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Orlando Sanford Intl to Santiago

Cheapest flights from Orlando Sanford Intl to Santiago
Explore the most affordable flight options available from Orlando Sanford Intl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:05 pmSFB - SCL
1 stop11h 50mMultiple Airlines
Sat 12/139:10 pmSCL - SFB
2 stops18h 25mMultiple Airlines
Deal found 10/27$618
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/284:40 pmSFB - SCL
2 stops26h 04mMultiple Airlines
Sun 11/307:25 amSCL - SFB
3 stops38h 28mMultiple Airlines
Deal found 10/27$1,174
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/214:40 pmSFB - SCL
1 stop26h 55mMultiple Airlines
Fri 11/2811:10 pmSCL - SFB
2 stops41h 34mMultiple Airlines
Deal found 10/27$1,445

Cheap flight deals from Orlando Sanford Intl to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Orlando Sanford Intl (SFB) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$618
(Mytrip)

One-way from

$180
(Orbitz)

Popular in

December

Cheapest in

August

Average price

$567
Provider with most accurate pricing for Orlando Sanford Intl-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Orlando Sanford Intl-Santiago Arturo Merino Benitez flights.
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From Orlando Sanford Intl to Santiago Arturo Merino Benitez
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One-way flight from Orlando Sanford Intl to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($59 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Orlando Sanford Intl to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Orlando Sanford Intl Airport to Santiago that are best for you.

Fly from

Orlando Sanford Intl

Fly to

Santiago

Route

Depart

Return

Price

OrlandoSantiago

SFB - SCL

SFBSCL

Orlando Sanford Intl

Sun 12/7

3:05 pm-4:55 am

1 stop11h 50m

Santiago Arturo Merino Benitez

Sat 12/13

9:10 pm-1:35 pm

2 stops18h 25m

$618

OrlandoSantiago

SFB - SCL

SFBSCL

Orlando Sanford Intl

Fri 11/28

4:40 pm-8:44 pm

2 stops26h 04m

Santiago Arturo Merino Benitez

Sun 11/30

7:25 am-7:53 pm

3 stops38h 28m

$1,174

OrlandoSantiago

SFB - SCL

SFBSCL

Orlando Sanford Intl

Fri 11/21

4:40 pm-9:35 pm

1 stop26h 55m

Santiago Arturo Merino Benitez

Fri 11/28

11:10 pm-2:44 pm

2 stops41h 34m

$1,445

OrlandoSantiago

SFB - SCL

SFBSCL

Orlando Sanford Intl

Sun 11/16

3:05 pm-4:55 am

1 stop11h 50m

$180

OrlandoSantiago

SFB - SCL

SFBSCL

Orlando Sanford Intl

Tue 11/11

2:15 pm-4:00 am

1 stop11h 45m

$195

OrlandoSantiago

SFB - SCL

SFBSCL

Orlando Sanford Intl

Sun 11/9

3:05 pm-4:55 am

1 stop11h 50m

$206

OrlandoSantiago

SFB - SCL

SFBSCL

Orlando Sanford Intl

Sun 11/23

3:05 pm-4:55 am

1 stop11h 50m

$260

OrlandoSantiago

SFB - SCL

SFBSCL

Orlando Sanford Intl

Sun 11/16

3:05 pm-5:25 pm

2 stops24h 20m

$297

OrlandoSantiago

SFB - SCL

SFBSCL

Orlando Sanford Intl

Tue 11/11

2:15 pm-12:15 pm

3 stops44h 00m

$300

OrlandoSantiago

SFB - SCL

SFBSCL

Orlando Sanford Intl

Tue 12/23

2:15 pm-4:00 am

1 stop11h 45m

$366

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 14 results
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Compare providers for flights from Orlando Sanford Intl to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Orlando Sanford Intl to Santiago in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Orlando Sanford Intl Airport-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Orlando Sanford Intl Airport-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Orlando Sanford Intl Airport-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Orlando Sanford Intl Airport-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Orlando Sanford Intl Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Orlando Sanford Intl to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Orlando Sanford Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Orlando Sanford Intl to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Orlando Sanford Intl?

    Most people fly into Santiago Arturo Merino Benitez (SCL) if they book a flight to Santiago from Orlando Sanford Intl. On average, Arturo Merino Benitez has 0 inbound flights from Orlando Sanford Intl per day from 0 airlines. Santiago Arturo Merino Benitez is conveniently located just 8.4 mi from Santiago’s city center.

  • Can I find deals for flights from Orlando Sanford Intl to Santiago that include hotel bookings?

    Yes. In addition to deals on Orlando Sanford Intl to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Orlando Sanford Intl to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Orlando Sanford Intl to Santiago.

  • Can I find deals for business class flights from Orlando Sanford Intl to Santiago?

    Yes. Cheapflights offers flight deals from Orlando Sanford Intl to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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