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$483+ Cheap flights from San Antonio (SAT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from San Antonio to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$736
(Kiwi.com)

One-way from

$483
(FlightHub)

Popular in

December

Cheapest in

November

Average price

$1,192
From San Antonio to Santiago Arturo Merino Benitez
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One-way flight from San Antonio to Santiago Arturo Merino Benitez
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High demand for flights, 8% potential price rise
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Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Antonio to Santiago

Cheapest flights from San Antonio to Santiago
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/265:55 pmSAT - SCL
1 stop35h 35mMultiple Airlines
Sun 11/27:25 amSCL - SAT
2 stops31h 38mMultiple Airlines
Deal found 9/10$736
This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:15 amSAT - SCL
2 stops21h 45mLATAM Airlines
Wed 11/265:15 amSCL - SAT
2 stops22h 18mLATAM Airlines
Deal found 9/10$761
This SmartFares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/266:21 pmSAT - SCL
1 stop35h 19mLATAM Airlines
Sun 11/211:10 pmSCL - SAT
1 stop15h 18mLATAM Airlines
Deal found 9/10$807
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:00 pmSAT - SCL
1 stop11h 50mUnited Airlines
Sat 11/2910:45 pmSCL - SAT
1 stop13h 03mUnited Airlines
Deal found 9/11$819
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/195:23 amSAT - SCL
1 stop24h 37mAmerican Airlines
Sat 11/2911:15 pmSCL - SAT
1 stop26h 40mAmerican Airlines
Deal found 9/10$841
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/195:15 amSAT - SCL
2 stops22h 20mDelta
Fri 11/2812:55 amSCL - SAT
2 stops22h 26mDelta
Deal found 9/10$874

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.

Fly from

San Antonio

Fly to

Santiago

Route

Depart

Return

Price

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sun 10/26

5:55 pm-7:30 am

1 stop35h 35m

Santiago Arturo Merino Benitez

Sun 11/2

7:25 am-12:03 pm

2 stops31h 38m

$736

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 1/22

7:00 am-7:00 am

1 stop21h 00m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-11:33 pm

2 stops28h 18m

$756

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sat 11/22

3:30 pm-7:40 am

1 stop13h 10m

Santiago Arturo Merino Benitez

Wed 11/26

11:10 pm-10:40 am

1 stop14h 30m

$774

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

7:00 am-2:05 pm

2 stops28h 05m

Santiago Arturo Merino Benitez

Sun 2/1

4:40 pm-11:33 pm

2 stops33h 53m

$791

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 1/20

10:45 am-7:00 am

1 stop17h 15m

Santiago Arturo Merino Benitez

Sun 2/1

6:30 pm-1:26 pm

2 stops21h 56m

$794

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 3/5

5:30 am-6:35 am

2 stops22h 05m

Santiago Arturo Merino Benitez

Sat 3/14

11:55 pm-2:40 pm

1 stop16h 45m

$794

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 1/22

7:00 am-7:00 am

1 stop21h 00m

Santiago Arturo Merino Benitez

Sun 2/1

6:30 pm-3:31 pm

2 stops24h 01m

$794

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Wed 1/14

5:30 am-5:35 am

2 stops21h 05m

$483

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 2/2

10:45 am-7:00 am

2 stops17h 15m

$518

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Wed 1/14

11:00 am-7:50 am

1 stop17h 50m

$518

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 14 results
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Best time to book a flight from San Antonio to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Santiago

What is the cheapest month to book a flight from San Antonio to Santiago?

Currently, April is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $752). Flying from San Antonio to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from San Antonio to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Antonio to Santiago?

    A quick flight from San Antonio to Santiago can take about 21h. LATAM Airlines provides one of the quickest options available for as low as $756. San Antonio and Santiago are separated by a distance of 4706 mi.

  • What are the cheapest airlines flying from San Antonio to Santiago round-trip?

    United Airlines, at $566, was found to be the cheapest airline from San Antonio to Santiago.Alternate airlines to your destination round-trip include Delta and American Airlines. United Airlines is priced at 44% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Antonio to Santiago that include hotel bookings?

    Yes. In addition to deals on San Antonio to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Santiago.

  • Can I find deals for business class flights from San Antonio to Santiago?

    Yes. Cheapflights offers flight deals from San Antonio to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Santiago?

    Currently, April is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $752). Flying from San Antonio to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from San Antonio to Santiago

Discover the top 4 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$566Average$950FlexibilityNo cancel feeOn-time69%
DeltaCheapest$702Average$866FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$753Average$1,078FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$753Average$1,090FlexibilityNo cancel feeOn-time81%

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