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$431+ Cheap flights from San Antonio (SAT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from San Antonio to Santiago

Cheapest flights from San Antonio to Santiago
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:45 pm
SAT
-
SCL
1 stop25h 30m
Multiple Airlines
Thu 3/195:21 am
SCL
-
SAT
2 stops30h 11m
Multiple Airlines
Deal found 1/26$800
This LATAM Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/234:29 pm
SAT
-
SCL
2 stops19h 36m
LATAM Airlines
Wed 4/18:45 am
SCL
-
SAT
2 stops17h 53m
LATAM Airlines
Deal found 1/27$820
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:10 pm
SAT
-
SCL
1 stop15h 40m
United Airlines
Wed 3/119:45 pm
SCL
-
SAT
1 stop17h 29m
United Airlines
Deal found 1/26$823
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/233:08 pm
SAT
-
SCL
1 stop13h 57m
American Airlines
Mon 3/211:55 pm
SCL
-
SAT
2 stops17h 30m
American Airlines
Deal found 1/25$825
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/234:45 pm
SAT
-
SCL
2 stops37h 05m
United Airlines
Mon 3/210:45 pm
SCL
-
SAT
2 stops21h 10m
United Airlines
Deal found 1/25$842
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:15 pm
SAT
-
SCL
1 stop15h 35m
United Airlines
Thu 11/510:45 pm
SCL
-
SAT
1 stop17h 18m
United Airlines
Deal found 1/25$845
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:52 pm
SAT
-
SCL
1 stop10h 58m
United Airlines
Sat 3/149:45 pm
SCL
-
SAT
1 stop15h 02m
United Airlines
Deal found 1/28$860
This KAYAK deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:30 am
SAT
-
SCL
2 stops22h 30m
LATAM Airlines
Fri 3/1312:20 am
SCL
-
SAT
2 stops35h 35m
LATAM Airlines
Deal found 1/28$865
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:10 pm
SAT
-
SCL
2 stops22h 55m
Delta
Fri 9/48:40 pm
SCL
-
SAT
1 stop19h 36m
Delta
Deal found 1/25$885

Find flight deals from San Antonio to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$800
(Kiwi.com)

One-way from

$431
(Kiwi.com)

Popular in

June

Cheapest in

September

Average price

$816
Provider with most accurate pricing for San Antonio-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Antonio-Santiago Arturo Merino Benitez flights.
Search Deals
From San Antonio to Santiago Arturo Merino Benitez
Search Deals
One-way flight from San Antonio to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($127 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.

Fly from

San Antonio

Fly to

Santiago

Route

Depart

Return

Price

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 3/23

12:24 pm-7:40 am

1 stop17h 16m

Santiago Arturo Merino Benitez

Tue 3/31

12:25 am-6:14 pm

2 stops19h 49m

$820

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 3/12

9:52 am-7:50 am

1 stop19h 58m

Santiago Arturo Merino Benitez

Thu 3/19

9:45 pm-10:47 am

1 stop15h 02m

$820

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 2/23

7:00 am-8:05 am

1 stop22h 05m

Santiago Arturo Merino Benitez

Mon 3/2

11:15 pm-5:04 pm

1 stop20h 49m

$820

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 2/26

2:10 pm-8:50 am

1 stop15h 40m

Santiago Arturo Merino Benitez

Wed 3/11

9:45 pm-1:14 pm

1 stop17h 29m

$823

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 2/23

4:45 pm-8:50 am

2 stops37h 05m

Santiago Arturo Merino Benitez

Mon 3/2

10:45 pm-4:55 pm

2 stops21h 10m

$842

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 3/5

6:52 pm-8:50 am

1 stop10h 58m

Santiago Arturo Merino Benitez

Sat 3/14

9:45 pm-10:47 am

1 stop15h 02m

$860

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 3/5

8:00 am-5:35 am

2 stops18h 35m

Santiago Arturo Merino Benitez

Fri 3/13

12:20 am-9:55 am

2 stops35h 35m

$865

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sat 3/7

7:37 pm-8:09 am

3 stops57h 32m

$431

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sat 3/7

5:30 am-5:35 am

2 stops21h 05m

$438

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sat 3/7

4:10 pm-8:50 am

1 stop13h 40m

$438

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Compare providers for flights from San Antonio to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Santiago in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Antonio-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Antonio-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Antonio to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Santiago

What is the cheapest month to book a flight from San Antonio to Santiago?

Currently, September is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $260). Flying from San Antonio to Santiago in December is currently the most expensive (average of $703). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from San Antonio to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated January 28, 2026.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,123 reviews

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,123 reviews
Delta
7.9
Good
8,123 reviews

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,915 reviews
Delta
7.9
Good
8,123 reviews

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,208 reviews
Delta
7.9
Good
8,123 reviews

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,201 reviews
Delta
7.9
Good
8,123 reviews

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Antonio to Santiago?

    A quick flight from San Antonio to Santiago can take about 17h 16m. LATAM Airlines provides one of the quickest options available for as low as $820. San Antonio and Santiago are separated by a distance of 4706 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Antonio to Santiago round-trip?

    United Airlines, at $566, was found to be the cheapest airline from San Antonio to Santiago.Alternate airlines to your destination round-trip include American Airlines and Delta. United Airlines is priced at 40% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Antonio to Santiago that include hotel bookings?

    Yes. In addition to deals on San Antonio to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Santiago.

  • Can I find deals for business class flights from San Antonio to Santiago?

    Yes. Cheapflights offers flight deals from San Antonio to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Santiago?

    Currently, September is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $260). Flying from San Antonio to Santiago in December is currently the most expensive (average of $703). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from San Antonio to Santiago

Discover the top 4 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$566Average$795FlexibilityNo cancel feeOn-time69%
DeltaCheapest$753Average$1,002FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$753Average$983FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$753Average$1,090FlexibilityNo cancel feeOn-time81%

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