$434+ Cheap flights from San Antonio (SAT) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
Nov 23 — Nov 301
Round-trip
1 adult, Economy
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Find cheap flights from San Antonio to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Santiago
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Cheapest flights from San Antonio to SantiagoExplore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
This Mytrip deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:47 pm -
2 stops30h 21m
Mon 12/149:55 pm -
2 stops23h 06m
Deal found 10/23![Multiple Airlines logo]()
$976
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:45 pm -
1 stop12h 05m
Mon 12/1410:45 pm -
1 stop12h 44m
Deal found 10/23![United Airlines logo]()
$999
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/711:47 am -
1 stop18h 03m
Thu 12/1010:45 pm -
1 stop21h 52m
Deal found 10/21![United Airlines logo]()
$1,008
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:01 am -
1 stop25h 14m
Fri 12/1110:30 pm -
1 stop18h 42m
Deal found 10/21![American Airlines logo]()
$1,010
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/62:05 pm -
1 stop15h 10m
Sun 12/1311:15 pm -
1 stop22h 07m
Deal found 10/22![American Airlines logo]()
$1,011
This LATAM Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/161:44 pm -
3 stops22h 16m
Mon 11/237:05 pm -
2 stops17h 54m
Deal found 10/19![LATAM Airlines logo]()
$1,012
This LATAM Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/71:45 pm -
3 stops22h 15m
Mon 12/147:05 pm -
2 stops20h 35m
Deal found 10/23![LATAM Airlines logo]()
$1,088
This eDestinos deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:47 pm -
2 stops30h 21m
Fri 12/115:01 am -
3 stops34h 39m
Deal found 10/21![Multiple Airlines logo]()
$1,089
Best flights from San Antonio to SantiagoDiscover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
Discover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:45 pm -
1 stop12h 05m
Mon 12/1410:45 pm -
1 stop12h 44m
Deal found 10/23![United Airlines logo]()
$999
This LATAM Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:16 am -
1 stop23h 24m
Thu 12/1011:10 pm -
1 stop16h 30m
Deal found 10/19![LATAM Airlines logo]()
$1,008
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:30 am -
1 stop23h 10m
Mon 11/2311:55 pm -
1 stop17h 55m
Deal found 10/19![Delta logo]()
$1,008
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:53 pm -
2 stops59h 02m
Fri 12/119:35 am -
1 stop30h 31m
Deal found 10/20![Multiple Airlines logo]()
$1,008
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/512:46 pm -
2 stops17h 19m
Fri 4/168:35 pm -
2 stops20h 03m
Deal found 10/22![American Airlines logo]()
$1,070
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:38 am -
2 stops20h 52m
Mon 12/1411:10 pm -
1 stop19h 24m
Deal found 10/23![Delta logo]()
$1,008
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/711:47 am -
1 stop18h 03m
Thu 12/1010:45 pm -
1 stop21h 52m
Deal found 10/21![United Airlines logo]()
$1,008
This LATAM Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/115:30 am -
2 stops23h 00m
Sat 4/104:50 pm -
2 stops21h 32m
Deal found 10/22![LATAM Airlines logo]()
$1,077
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/76:45 am -
1 stop23h 30m
Thu 4/1511:25 pm -
1 stop16h 14m
Deal found 10/21![Delta logo]()
$1,066
Last-minute flights from San Antonio to SantiagoDiscover last-minute flight deals from San Antonio to Santiago. Data last updated October 24, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Santiago. Data last updated October 24, 2026 and is based on user searches.
This Orbitz deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:23 pm -
1 stop29h 52m
Fri 10/3011:10 pm -
1 stop22h 38m
Deal found 10/21![Multiple Airlines logo]()
$1,489
This Orbitz deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:41 pm -
2 stops26h 19m
Fri 10/308:15 am -
3 stops37h 33m
Deal found 10/21![LATAM Airlines logo]()
$1,595
This Cheapflightsfares deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:30 am -
1 stop23h 10m
Wed 11/1111:10 pm -
1 stop16h 29m
Deal found 10/20![LATAM Airlines logo]()
$1,111
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:50 am -
2 stops21h 40m
Wed 11/1111:55 pm -
1 stop17h 55m
Deal found 10/20![Delta logo]()
$1,112
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:47 pm -
3 stops35h 33m
Tue 11/102:10 am -
3 stops32h 51m
Deal found 10/20![Multiple Airlines logo]()
$1,435
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:30 am -
1 stop23h 10m
Mon 11/2311:55 pm -
1 stop17h 55m
Deal found 10/19![Delta logo]()
$1,008
This LATAM Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/161:44 pm -
3 stops22h 16m
Mon 11/237:05 pm -
2 stops17h 54m
Deal found 10/19![LATAM Airlines logo]()
$1,012
This Mytrip deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:47 pm -
3 stops33h 03m
Mon 11/234:15 pm -
3 stops30h 08m
Deal found 10/19![Multiple Airlines logo]()
$1,478
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:47 pm -
3 stops21h 13m
Mon 12/79:55 pm -
3 stops27h 02m
Deal found 10/21![Multiple Airlines logo]()
$1,440
One-way flights from San Antonio to SantiagoSearch for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
Search for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:29 pm -
3 stops54h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$434
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:00 am -
2 stops30h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$461
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:25 am -
3 stops31h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$493
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:00 am -
2 stops30h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$510
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:45 pm -
2 stops28h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$512
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:11 pm -
3 stops49h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:00 am -
2 stops30h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$524
This oojo deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:01 pm -
1 stop29h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Aeromexico logo]()
$526
Find flight deals from San Antonio to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 24, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $976 (Mytrip) |
One-way from | $434 (Kiwi.com) |
Popular in | December |
Cheapest in | March |
Average price | $1,322 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Tue 11/10
1:01 pm-9:15 pm
1 stop29h 14m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$526
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Tue 11/10
8:53 pm-3:38 am
3 stops27h 45m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$548
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Tue 11/10
2:20 pm-8:50 am
1 stop15h 30m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$745
Quickest round-trip
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Wed 11/11
1:44 pm-7:40 am
1 stop14h 56m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$745
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Thu 11/12
5:30 am-7:40 am
1 stop23h 10m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$745
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Sat 11/7
7:50 am-7:40 am
1 stop20h 50m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$775
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Mon 12/7
5:45 pm-8:50 am
1 stop12h 05m
Santiago Arturo Merino Benitez
Mon 12/14
10:45 pm-8:29 am
1 stop12h 44m
$999
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Mon 12/7
5:16 am-7:40 am
1 stop23h 24m
Santiago Arturo Merino Benitez
Thu 12/10
11:10 pm-12:40 pm
1 stop16h 30m
$1,008
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Mon 11/16
5:30 am-7:40 am
1 stop23h 10m
Santiago Arturo Merino Benitez
Mon 11/23
11:55 pm-2:50 pm
1 stop17h 55m
$1,008
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Fri 12/4
8:53 pm-10:55 am
2 stops59h 02m
Santiago Arturo Merino Benitez
Fri 12/11
9:35 am-1:06 pm
1 stop30h 31m
$1,008
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Santiago in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Antonio-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Antonio-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
SAT-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Santiago
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated October 24, 2026.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentStacey-Ann,Aug 2023
IAH - ATL
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentStacey-Ann,Aug 2023
IAH - ATL
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentStacey-Ann,Aug 2023
IAH - ATL
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentStacey-Ann,Aug 2023
IAH - ATL
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentStacey-Ann,Aug 2023
IAH - ATL
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for San Antonio to Santiago
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Antonio to Santiago by cabin class
Find flights from San Antonio to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Antonio and Santiago flights
Browse other San Antonio and Santiago flight options. Last updated on October 24, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on October 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 24, 2026.
Top 4 airlines flying from San Antonio to Santiago
Discover the top 4 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$637 | Average$1,219 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$754 | Average$900 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$805 | Average$1,414 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$995 | Average$1,256 | FlexibilityNo cancel fee | On-time81% |