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$377+ Cheap flights from San Antonio (SAT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
Apr 29 — May 61
Wed 4/29
Wed 5/6
1 adult, Economy
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Cheap flight deals from San Antonio to Santiago

Cheapest flights from San Antonio to Santiago
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 30, 2026.

This Mytrip deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:12 pm
SAT
-
SCL
2 stops32h 08m
Multiple Airlines
Wed 4/226:40 am
SCL
-
SAT
3 stops42h 11m
Multiple Airlines
Deal found 3/29$795
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:22 am
SAT
-
SCL
3 stops35h 58m
Multiple Airlines
Thu 4/163:20 pm
SCL
-
SAT
3 stops33h 31m
Multiple Airlines
Deal found 3/30$813
This Mytrip deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:12 pm
SAT
-
SCL
2 stops23h 03m
Multiple Airlines
Fri 5/112:30 am
SCL
-
SAT
2 stops24h 21m
Multiple Airlines
Deal found 3/28$853
This KAYAK deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:30 pm
SAT
-
SCL
1 stop13h 45m
LATAM Airlines
Mon 4/201:30 pm
SCL
-
SAT
2 stops22h 51m
LATAM Airlines
Deal found 3/26$890

Find flight deals from San Antonio to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$795
(Mytrip)

One-way from

$553
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$875
Provider with most accurate pricing for San Antonio-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Antonio-Santiago Arturo Merino Benitez flights.
Search Deals
From San Antonio to Santiago Arturo Merino Benitez
Search Deals
One-way flight from San Antonio to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($147 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($37 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 4/20

2:12 pm-2:15 pm

2 stops23h 03m

Santiago Arturo Merino Benitez

Wed 4/22

3:20 pm-11:51 pm

2 stops33h 31m

$811

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 4/13

4:30 pm-1:25 pm

3 stops19h 55m

Santiago Arturo Merino Benitez

Mon 4/20

6:45 pm-11:21 am

2 stops17h 36m

$895

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sun 5/10

6:21 pm-6:00 am

2 stops34h 39m

Santiago Arturo Merino Benitez

Sun 5/17

7:55 pm-11:03 am

2 stops16h 08m

$944

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 6/1

7:55 am-6:00 am

2 stops21h 05m

Santiago Arturo Merino Benitez

Wed 6/10

7:45 pm-11:10 am

2 stops16h 25m

$985
Quickest round-trip

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Wed 6/10

2:29 pm-7:15 am

1 stop15h 46m

Santiago Arturo Merino Benitez

Wed 6/17

8:40 pm-9:52 am

1 stop14h 12m

$985

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sat 5/9

5:00 pm-7:15 am

1 stop13h 15m

Santiago Arturo Merino Benitez

Sat 5/16

11:05 pm-8:28 pm

2 stops22h 23m

$986

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sat 5/9

1:32 pm-7:05 am

2 stops16h 33m

Santiago Arturo Merino Benitez

Sat 5/16

8:35 pm-11:15 pm

1 stop27h 40m

$990

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sun 5/10

7:55 am-6:00 am

2 stops21h 05m

Santiago Arturo Merino Benitez

Sun 5/17

8:40 pm-3:06 pm

1 stop19h 26m

$990

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Fri 5/29

12:24 pm-7:05 am

2 stops17h 41m

Santiago Arturo Merino Benitez

Fri 6/5

9:00 pm-5:45 pm

1 stop21h 45m

$995

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Fri 5/29

10:16 pm-4:11 am

3 stops28h 55m

Santiago Arturo Merino Benitez

Thu 6/4

3:35 am-9:05 am

3 stops30h 30m

$1,013

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from San Antonio to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Santiago in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Antonio-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Antonio-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Antonio to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Santiago

What is the cheapest month to book a flight from San Antonio to Santiago?

Currently, September is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $260). Flying from San Antonio to Santiago in December is currently the most expensive (average of $703). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from San Antonio to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated March 30, 2026.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,360 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,360 reviews
Delta
7.9
Good
8,360 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.4
Good
1,902 reviews
Delta
7.9
Good
8,360 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,517 reviews
Delta
7.9
Good
8,360 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,529 reviews
Delta
7.9
Good
8,360 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from San Antonio to Santiago round-trip?

    United Airlines, at $566, was found to be the cheapest airline from San Antonio to Santiago.Alternate airlines to your destination round-trip include American Airlines and Delta. United Airlines is priced at 42% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Antonio to Santiago that include hotel bookings?

    Yes. In addition to deals on San Antonio to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Santiago.

  • Can I find deals for business class flights from San Antonio to Santiago?

    Yes. Cheapflights offers flight deals from San Antonio to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Santiago?

    Currently, September is the cheapest month in which you can book a flight from San Antonio to Santiago (average of $260). Flying from San Antonio to Santiago in December is currently the most expensive (average of $703). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Antonio to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to Santiago flights
Austin to Santiago flights
George Bush Intcntl to Santiago flights

Top 4 airlines flying from San Antonio to Santiago

Discover the top 4 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$566Average$875FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$753Average$1,116FlexibilityNo cancel feeOn-time71%
DeltaCheapest$778Average$1,273FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$796Average$1,090FlexibilityNo cancel feeOn-time81%

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