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$348+ Cheap flights from Columbus (CMH) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — SCL
Dec 14 — Dec 211
Sun 12/14
Sun 12/21
1 adult, Economy
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Cheap flight deals from Columbus to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 14, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$715
(FlightHub)

One-way from

$348
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$896
Provider with most accurate pricing for Columbus-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Columbus-Santiago Arturo Merino Benitez flights.
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From Columbus to Santiago Arturo Merino Benitez
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One-way flight from Columbus to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 8% potential increase in price ($99 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Columbus to Santiago

Cheapest flights from Columbus to Santiago
Explore the most affordable flight options available from Columbus to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2025.

This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:08 pmCMH - SCL
1 stop12h 52mAmerican Airlines
Sun 11/3011:15 pmSCL - CMH
1 stop25h 15mAmerican Airlines
Deal found 11/13$915
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:48 pmCMH - SCL
1 stop12h 52mLATAM Airlines
Fri 12/2611:10 pmSCL - CMH
1 stop20h 16mLATAM Airlines
Deal found 11/11$921
This Ovago deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:39 pmCMH - SCL
1 stop35h 01mLATAM Airlines
Sat 12/2711:10 pmSCL - CMH
1 stop15h 00mLATAM Airlines
Deal found 11/11$978
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2510:00 amCMH - SCL
2 stops16h 30mDelta
Sun 11/3011:10 pmSCL - CMH
1 stop18h 34mDelta
Deal found 11/12$1,030
This Mytrip deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:00 amCMH - SCL
3 stops20h 30mMultiple Airlines
Sun 11/304:50 pmSCL - CMH
3 stops33h 01mMultiple Airlines
Deal found 11/13$1,046
This Orbitz deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/251:47 pmCMH - SCL
1 stop15h 53mLATAM Airlines
Sat 11/294:35 pmSCL - CMH
2 stops42h 20mLATAM Airlines
Deal found 11/13$1,068
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:00 amCMH - SCL
1 stop23h 00mAmerican Airlines
Sun 11/3011:15 pmSCL - CMH
1 stop21h 38mAmerican Airlines
Deal found 11/12$1,114

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 14, 2025.
Use the filters below to find and compare flights from Columbus Airport to Santiago that are best for you.

Fly from

Columbus

Fly to

Santiago

Route

Depart

Return

Price

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Tue 1/20

12:55 pm-6:55 am

1 stop16h 00m

Santiago Arturo Merino Benitez

Tue 2/3

6:30 pm-11:59 am

2 stops19h 29m

$732

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 2/2

4:33 pm-7:40 am

1 stop13h 07m

Santiago Arturo Merino Benitez

Tue 2/24

11:30 pm-12:01 pm

1 stop14h 31m

$754

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 2/2

5:33 am-10:39 am

3 stops27h 06m

Santiago Arturo Merino Benitez

Mon 2/23

4:57 am-9:40 am

3 stops30h 43m

$782

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 4/27

12:05 pm-6:00 am

1 stop17h 55m

Santiago Arturo Merino Benitez

Tue 5/5

4:15 am-11:58 pm

2 stops19h 43m

$787

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 5/13

7:55 pm-12:25 pm

2 stops16h 30m

Santiago Arturo Merino Benitez

Wed 5/20

10:55 pm-6:02 pm

1 stop19h 07m

$787

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 5/13

12:50 pm-6:00 am

2 stops17h 10m

Santiago Arturo Merino Benitez

Wed 5/20

4:55 pm-11:36 am

2 stops18h 41m

$804

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 12/1

8:06 pm-5:30 am

2 stops31h 24m

$348

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 1/23

9:30 am-6:50 am

2 stops43h 20m

$420

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Tue 11/25

6:00 am-5:30 am

2 stops21h 30m

$420

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 1/23

7:05 am-6:55 am

1 stop21h 50m

$517

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/13

Showing 1-10 of 11 results
1
2

Compare providers for flights from Columbus to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Santiago in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbus Airport-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Columbus Airport-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Columbus Airport-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbus Airport-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbus to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Santiago

What is the cheapest month to book a flight from Columbus Airport to Santiago?

Currently, March is the cheapest month in which you can book a flight from Columbus Airport to Santiago (average of $732). Flying from Columbus Airport to Santiago in June is currently the most expensive (average of $1,073). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SCL?

Find hourly flight availability from Columbus to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 14, 2025.

When flying from Columbus Airport to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 25% versus a flight in the evening.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated November 14, 2025.
Get a feel of what it's like to fly with Delta and LATAM Airlines from Columbus Airport to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,009 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,009 reviews
Delta
7.9
Good
8,009 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,876 reviews
Delta
7.9
Good
8,009 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Columbus?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Columbus. Booking flights from Columbus to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Columbus from 2 different airlines.

  • How long is the flight from Columbus Airport to Santiago?

    For as low as $732, LATAM Airlines can have you in Santiago from Columbus Airport in 16h. Columbus Airport and Santiago are separated by a distance of 5126 mi.

  • What are the cheapest airlines flying from Columbus Airport to Santiago round-trip?

    According to our current data, Delta ($732), and LATAM Airlines ($732) offers the cheapest pricing from Columbus Airport to Santiago. Delta is currently priced 28% below the average price you’ll pay for this route.

  • Can I find deals for flights from Columbus to Santiago that include hotel bookings?

    Yes. In addition to deals on Columbus to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Santiago.

  • Can I find deals for business class flights from Columbus to Santiago?

    Yes. Cheapflights offers flight deals from Columbus to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Santiago?

    Currently, March is the cheapest month in which you can book a flight from Columbus Airport to Santiago (average of $732). Flying from Columbus Airport to Santiago in June is currently the most expensive (average of $1,073). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
Temuco car rentals
Lastarria car rentals

Top 2 airlines flying from Columbus to Santiago

Discover the top 2 airlines that operate flights from Columbus to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$732Average$1,033FlexibilityNo cancel feeOn-time81%
DeltaCheapest$732Average$929FlexibilityNo cancel feeOn-timeN/A

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