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$420+ Cheap flights from Columbus (CMH) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — SCL
Nov 12 — Nov 191
Wed 11/12
Wed 11/19
1 adult, Economy
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Cheap flight deals from Columbus to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$799
(Avianca Connect)

One-way from

$420
(Air Canada)

Popular in

December

Cheapest in

October

Average price

$824
Provider with most accurate pricing for Columbus-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Columbus-Santiago Arturo Merino Benitez flights.
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From Columbus to Santiago Arturo Merino Benitez
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One-way flight from Columbus to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 5% potential increase in price ($59 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Columbus to Santiago

Cheapest flights from Columbus to Santiago
Explore the most affordable flight options available from Columbus to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2025.

This Avianca Connect deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:25 amCMH - SCL
2 stops22h 05mMultiple Airlines
Mon 11/171:35 amSCL - CMH
2 stops23h 35mMultiple Airlines
Deal found 10/11$799
This CheapOair deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:03 amCMH - SCL
1 stop21h 52mLATAM Airlines
Tue 11/1811:30 pmSCL - CMH
1 stop20h 10mLATAM Airlines
Deal found 10/11$802
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/712:17 pmCMH - SCL
2 stops14h 13mDelta
Tue 11/1811:10 pmSCL - CMH
1 stop20h 24mDelta
Deal found 10/11$804
This LATAM Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1712:18 pmCMH - SCL
2 stops17h 07mLATAM Airlines
Fri 10/245:15 amSCL - CMH
2 stops19h 44mLATAM Airlines
Deal found 10/10$844
This Trip.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1712:28 pmCMH - SCL
2 stops25h 23mMultiple Airlines
Thu 10/2312:05 amSCL - CMH
2 stops18h 11mMultiple Airlines
Deal found 10/10$847
This CheapOair deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:39 pmCMH - SCL
2 stops33h 56mLATAM Airlines
Sun 11/3010:25 pmSCL - CMH
2 stops27h 49mLATAM Airlines
Deal found 10/12$1,073
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1712:18 pmCMH - SCL
2 stops16h 27mDelta
Fri 10/2410:50 pmSCL - CMH
1 stop19h 41mDelta
Deal found 10/10$1,074
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:00 amCMH - SCL
1 stop23h 00mAmerican Airlines
Sun 11/3010:25 pmSCL - CMH
1 stop22h 34mAmerican Airlines
Deal found 10/12$1,094

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
Use the filters below to find and compare flights from Columbus Airport to Santiago that are best for you.

Fly from

Columbus

Fly to

Santiago

Route

Depart

Return

Price

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 11/7

5:25 am-5:30 am

2 stops22h 05m

Santiago Arturo Merino Benitez

Mon 11/17

1:35 am-11:10 pm

2 stops23h 35m

$799

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 11/7

7:03 am-6:55 am

1 stop21h 52m

Santiago Arturo Merino Benitez

Tue 11/18

11:30 pm-5:40 pm

1 stop20h 10m

$802

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 11/7

7:03 am-6:55 am

1 stop21h 52m

Santiago Arturo Merino Benitez

Mon 11/17

12:50 am-5:34 pm

2 stops18h 44m

$804

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Tue 3/17

9:30 am-11:15 am

1 stop24h 45m

Santiago Arturo Merino Benitez

Thu 3/19

7:55 pm-8:56 pm

1 stop26h 01m

$883

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 11/21

6:39 pm-6:35 am

2 stops33h 56m

Santiago Arturo Merino Benitez

Sun 11/30

10:25 pm-12:14 am

2 stops27h 49m

$1,073

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 11/21

7:00 am-8:00 am

1 stop23h 00m

Santiago Arturo Merino Benitez

Sun 11/30

10:25 pm-6:59 pm

1 stop22h 34m

$1,094

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Tue 3/17

11:05 am-6:35 am

2 stops18h 30m

Santiago Arturo Merino Benitez

Thu 3/19

8:50 am-11:57 pm

2 stops16h 07m

$1,094

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 1/23

9:30 am-7:00 am

2 stops43h 30m

$420

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 1/23

4:35 pm-2:30 pm

3 stops19h 55m

$569

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/11

Compare providers for flights from Columbus to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Santiago in October.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbus Airport-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbus Airport-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbus Airport-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbus Airport-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbus to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Santiago

What is the cheapest month to book a flight from Columbus Airport to Santiago?

Currently, March is the cheapest month in which you can book a flight from Columbus Airport to Santiago (average of $732). Flying from Columbus Airport to Santiago in June is currently the most expensive (average of $1,073). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SCL?

Find hourly flight availability from Columbus to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 13, 2025.

When flying from Columbus Airport to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 25% versus a flight in the evening.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated October 13, 2025.
Get a feel of what it's like to fly with Delta and LATAM Airlines from Columbus Airport to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,971 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,971 reviews
Delta
8.0
Very good
7,971 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
LATAM Airlines
7.5
Good
1,864 reviews
Delta
8.0
Very good
7,971 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Columbus?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Columbus. Booking flights from Columbus to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Columbus from 2 different airlines.

  • How long is the flight from Columbus Airport to Santiago?

    For as low as $802, LATAM Airlines can have you in Santiago from Columbus Airport in 21h 52m. Columbus Airport and Santiago are separated by a distance of 5126 mi.

  • What are the cheapest airlines flying from Columbus Airport to Santiago round-trip?

    According to our current data, Delta ($732), and LATAM Airlines ($732) offers the cheapest pricing from Columbus Airport to Santiago. Delta is currently priced 24% below the average price you’ll pay for this route.

  • Can I find deals for flights from Columbus to Santiago that include hotel bookings?

    Yes. In addition to deals on Columbus to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Santiago.

  • Can I find deals for business class flights from Columbus to Santiago?

    Yes. Cheapflights offers flight deals from Columbus to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Santiago?

    Currently, March is the cheapest month in which you can book a flight from Columbus Airport to Santiago (average of $732). Flying from Columbus Airport to Santiago in June is currently the most expensive (average of $1,073). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
Temuco car rentals
Lastarria car rentals

Top 2 airlines flying from Columbus to Santiago

Discover the top 2 airlines that operate flights from Columbus to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$732Average$1,026FlexibilityNo cancel feeOn-time81%
DeltaCheapest$732Average$929FlexibilityNo cancel feeOn-timeN/A

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