$500+ Cheap flights from Madrid, Spain (MAD) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
Jun 11 — Jun 181
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Madrid to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or May, booked 72 days in advance, depart on a Monday or Wednesday and return on a Sunday
Cheap flight deals from Madrid to Santiago
Cheapest
Best
Last-minute
One-way
Cheapest flights from Madrid to SantiagoExplore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3112:20 pm
MAD
- SCL
2 stops48h 55m
Delta
Tue 6/98:40 pm
SCL
- MAD
2 stops51h 40m
Delta
Deal found 5/11![Delta logo]()
$864
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:50 am
MAD
- SCL
1 stop27h 25m
Delta
Tue 6/28:40 pm
SCL
- MAD
2 stops33h 30m
Delta
Deal found 5/11![Delta logo]()
$867
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:35 pm
MAD
- SCL
2 stops46h 40m
Delta
Mon 11/2311:10 pm
SCL
- MAD
2 stops40h 25m
Delta
Deal found 5/10![Delta logo]()
$868
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
MAD
- SCL
2 stops31h 15m
Delta
Sun 10/48:40 pm
SCL
- MAD
2 stops33h 40m
Delta
Deal found 5/9![Delta logo]()
$869
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:55 am
MAD
- SCL
1 stop23h 45m
Delta
Tue 11/2411:10 pm
SCL
- MAD
1 stop30h 45m
Delta
Deal found 5/8![Delta logo]()
$872
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:59 pm
MAD
- SCL
Nonstop13h 26m
Iberia
Fri 6/1210:20 pm
SCL
- MAD
Nonstop12h 40m
Iberia
Deal found 5/7![Iberia logo]()
$873
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:50 am
MAD
- SCL
1 stop27h 25m
Delta
Mon 8/178:40 pm
SCL
- MAD
1 stop33h 35m
Delta
Deal found 5/11![Delta logo]()
$874
This Cheapflightsfares deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:15 pm
MAD
- SCL
Nonstop13h 20m
LATAM Airlines
Mon 6/297:10 am
SCL
- MAD
1 stop23h 05m
LATAM Airlines
Deal found 5/9![LATAM Airlines logo]()
$875
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:20 pm
MAD
- SCL
Nonstop13h 20m
Iberia
Sun 6/1410:40 am
SCL
- MAD
Nonstop12h 40m
Iberia
Deal found 5/11![Iberia logo]()
$877
This British Airways deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:59 pm
MAD
- SCL
Nonstop13h 26m
Iberia
Tue 6/910:40 am
SCL
- MAD
Nonstop12h 40m
Iberia
Deal found 5/8![Iberia logo]()
$878
This Expedia deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:59 pm
MAD
- SCL
Nonstop13h 26m
Iberia
Mon 6/2910:40 am
SCL
- MAD
Nonstop12h 40m
Iberia
Deal found 5/11![Iberia logo]()
$879
This British Airways deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:59 pm
MAD
- SCL
Nonstop13h 26m
Iberia
Sun 6/1410:40 am
SCL
- MAD
Nonstop12h 40m
Iberia
Deal found 5/11![Iberia logo]()
$880
Best flights from Madrid to SantiagoDiscover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
Discover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
This Turkish Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:25 pm
MAD
- SCL
2 stops54h 58m
Multiple Airlines
Mon 6/294:09 am
SCL
- MAD
2 stops48h 16m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$920
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/269:50 am
MAD
- SCL
1 stop27h 25m
Delta
Sun 9/208:40 pm
SCL
- MAD
2 stops28h 40m
Delta
Deal found 5/11![Delta logo]()
$944
This Turkish Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:00 pm
MAD
- SCL
3 stops47h 03m
Turkish Airlines
Tue 6/1610:15 am
SCL
- MAD
2 stops42h 10m
Turkish Airlines
Deal found 5/11![Turkish Airlines logo]()
$974
This Turkish Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:40 am
MAD
- SCL
2 stops45h 03m
Multiple Airlines
Sun 11/1511:40 am
SCL
- MAD
2 stops45h 40m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$934
This Turkish Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:25 pm
MAD
- SCL
2 stops43h 35m
Multiple Airlines
Sat 11/2812:28 pm
SCL
- MAD
2 stops44h 52m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$958
This Turkish Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:40 am
MAD
- SCL
3 stops51h 19m
Turkish Airlines
Tue 11/311:40 am
SCL
- MAD
2 stops24h 45m
Turkish Airlines
Deal found 5/11![Turkish Airlines logo]()
$1,066
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:50 am
MAD
- SCL
1 stop27h 25m
Delta
Sun 11/111:10 pm
SCL
- MAD
1 stop30h 45m
Delta
Deal found 5/11![Delta logo]()
$1,119
This Turkish Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:40 am
MAD
- SCL
3 stops51h 30m
Multiple Airlines
Tue 6/912:01 am
SCL
- MAD
2 stops52h 24m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$962
This Turkish Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/122:40 pm
MAD
- SCL
3 stops44h 23m
Multiple Airlines
Sun 6/219:15 am
SCL
- MAD
3 stops43h 10m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$1,038
This Turkish Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:25 pm
MAD
- SCL
3 stops40h 38m
Multiple Airlines
Sun 9/209:15 am
SCL
- MAD
3 stops44h 10m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$1,154
This Turkish Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:25 pm
MAD
- SCL
3 stops40h 38m
Multiple Airlines
Fri 6/1211:17 am
SCL
- MAD
2 stops41h 08m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$1,177
Last-minute flights from Madrid to SantiagoDiscover last-minute flight deals from Madrid to Santiago. Data last updated May 12, 2026 and is based on user searches.
Discover last-minute flight deals from Madrid to Santiago. Data last updated May 12, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:50 am
MAD
- SCL
1 stop27h 25m
Delta
Tue 6/28:40 pm
SCL
- MAD
2 stops27h 40m
Delta
Deal found 5/9![Delta logo]()
$884
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:50 am
MAD
- SCL
1 stop27h 25m
Delta
Tue 6/28:40 pm
SCL
- MAD
2 stops33h 30m
Delta
Deal found 5/11![Delta logo]()
$867
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:45 pm
MAD
- SCL
2 stops48h 30m
Delta
Tue 6/98:40 pm
SCL
- MAD
2 stops51h 40m
Delta
Deal found 5/11![Delta logo]()
$886
This British Airways deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:59 pm
MAD
- SCL
Nonstop13h 26m
Iberia
Tue 6/910:40 am
SCL
- MAD
Nonstop12h 40m
Iberia
Deal found 5/8![Iberia logo]()
$878
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3112:20 pm
MAD
- SCL
2 stops48h 55m
Delta
Tue 6/98:40 pm
SCL
- MAD
2 stops51h 40m
Delta
Deal found 5/11![Delta logo]()
$864
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:50 am
MAD
- SCL
1 stop27h 25m
Delta
Mon 8/178:40 pm
SCL
- MAD
1 stop33h 35m
Delta
Deal found 5/11![Delta logo]()
$874
This British Airways deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:59 pm
MAD
- SCL
Nonstop13h 26m
Iberia
Sun 6/1410:40 am
SCL
- MAD
Nonstop12h 40m
Iberia
Deal found 5/11![Iberia logo]()
$880
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:59 pm
MAD
- SCL
Nonstop13h 26m
Iberia
Fri 6/1210:20 pm
SCL
- MAD
Nonstop12h 40m
Iberia
Deal found 5/7![Iberia logo]()
$873
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:20 pm
MAD
- SCL
Nonstop13h 20m
Iberia
Sun 6/1410:40 am
SCL
- MAD
Nonstop12h 40m
Iberia
Deal found 5/11![Iberia logo]()
$877
This Cheapflightsfares deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:15 pm
MAD
- SCL
Nonstop13h 20m
LATAM Airlines
Mon 6/297:10 am
SCL
- MAD
1 stop23h 05m
LATAM Airlines
Deal found 5/9![LATAM Airlines logo]()
$875
This Expedia deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:59 pm
MAD
- SCL
Nonstop13h 26m
Iberia
Mon 6/2910:40 am
SCL
- MAD
Nonstop12h 40m
Iberia
Deal found 5/11![Iberia logo]()
$879
One-way flights from Madrid to SantiagoSearch for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
Search for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:20 pm
MAD
- SCL
Nonstop13h 20m
Iberia
Deal found 5/7![Iberia logo]()
$500
This Trip.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:20 pm
MAD
- SCL
Nonstop13h 20m
Iberia
Deal found 5/7![Iberia logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:55 am
MAD
- SCL
3 stops40h 04m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$540
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:00 pm
MAD
- SCL
Nonstop13h 20m
Iberia
Deal found 5/7![Iberia logo]()
$558
This Avianca deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/178:10 am
MAD
- SCL
1 stop21h 10m
Avianca
Deal found 5/8![Avianca logo]()
$559
This Avianca deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:20 am
MAD
- SCL
1 stop17h 55m
Avianca
Deal found 5/7![Avianca logo]()
$562
This Avianca deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:05 am
MAD
- SCL
1 stop23h 40m
Avianca
Deal found 5/11![Avianca logo]()
$564
This Avianca deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/308:05 pm
MAD
- SCL
2 stops33h 15m
Avianca
Deal found 5/8![Avianca logo]()
$570
This Avianca deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:05 am
MAD
- SCL
1 stop18h 15m
Avianca
Deal found 5/8![Avianca logo]()
$571
Find flight deals from Madrid to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $864 (Delta) |
One-way from | $500 (Kiwi.com) |
Popular in | July |
Cheapest in | March |
Average price | $967 |
Good round-trip deal | $989 or less |
Good one-way deal | $383 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 6/16
6:25 pm-7:23 pm
2 stops54h 58m
Santiago Arturo Merino Benitez
Mon 6/29
4:09 am-10:25 am
2 stops48h 16m
$920
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Sat 10/24
7:40 am-11:43 pm
2 stops45h 03m
Santiago Arturo Merino Benitez
Sun 11/15
11:40 am-1:20 pm
2 stops45h 40m
$934
Quickest round-trip
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 8/26
9:50 am-7:15 am
1 stop27h 25m
Santiago Arturo Merino Benitez
Sun 9/20
8:40 pm-6:20 am
2 stops28h 40m
$944
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 11/6
2:25 pm-6:00 am
2 stops43h 35m
Santiago Arturo Merino Benitez
Sat 11/28
12:28 pm-1:20 pm
2 stops44h 52m
$958
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 5/26
7:40 am-5:10 am
3 stops51h 30m
Santiago Arturo Merino Benitez
Tue 6/9
12:01 am-10:25 am
2 stops52h 24m
$962
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Tue 6/9
12:00 pm-5:03 am
3 stops47h 03m
Santiago Arturo Merino Benitez
Tue 6/16
10:15 am-10:25 am
2 stops42h 10m
$974
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Fri 6/12
2:40 pm-5:03 am
3 stops44h 23m
Santiago Arturo Merino Benitez
Sun 6/21
9:15 am-10:25 am
3 stops43h 10m
$1,038
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 9/16
7:40 am-5:59 am
3 stops51h 19m
Santiago Arturo Merino Benitez
Tue 11/3
11:40 am-4:25 pm
2 stops24h 45m
$1,066
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 9/16
9:50 am-8:15 am
1 stop27h 25m
Santiago Arturo Merino Benitez
Sun 11/1
11:10 pm-9:55 am
1 stop30h 45m
$1,119
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
Wed 8/26
6:25 pm-5:03 am
3 stops40h 38m
Santiago Arturo Merino Benitez
Sun 9/20
9:15 am-10:25 am
3 stops44h 10m
$1,154
Showing 1-10 of 16 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Madrid-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Madrid-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Madrid-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Madrid-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Madrid to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
MAD-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Santiago
Prices
Airlines
Delays
How far ahead should I book a flight from Madrid to Santiago?
The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 71 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of $941). Flying from Madrid to Santiago in July is currently the most expensive (average of $1,423). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to SCL?
Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 12, 2026.
It’s optimal to fly from Madrid to Santiago in the afternoon. By choosing this option you can save up to 48% on the cost of your flight, compared to a flight in the evening.
How often are flights from Madrid to Santiago delayed?
About 16% of weekly flights between Madrid and Santiago have experienced delays in the past year, with the average delay time being 126 minutes.
What is the most punctual flight time for Madrid to Santiago flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Madrid to Santiago flights?
Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 13% of flights being delayed.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated May 12, 2026.
Read reviews from past customers who have flown LATAM Airlines,Iberia, andAvianca from Madrid to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Overall
7.4
Food
6.7
Crew
8.0
Entertainment
7.0
Comfort
7.3
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Boarding
7.5
Overall
7.4
Food
6.7
Crew
8.0
Entertainment
7.0
Comfort
7.3
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Boarding
7.5
Overall
7.4
Food
6.7
Crew
8.0
Entertainment
7.0
Comfort
7.3
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Boarding
7.5
Overall
7.4
Food
6.7
Crew
8.0
Entertainment
7.0
Comfort
7.3
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Related info for your journey
Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Complete your trip
Flights by cabin class
Other flight options
Other flights from Madrid
Popular flights
Santiago flight routes
Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Madrid to Santiago by cabin class
Find flights from Madrid to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Madrid and Santiago flights
Browse other Madrid and Santiago flight options. Last updated on May 12, 2026.
Other flights from Madrid
Browse through other flights departing from Madrid. Flights are based on user searches made on Cheapflights and were last updated on May 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 12, 2026.
Top 3 airlines flying from Madrid to Santiago
Discover the top 3 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$502 | Average$922 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$755 | Average$1,296 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$878 | Average$1,284 | FlexibilityNo cancel fee | On-time81% |