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$540+ Cheap flights from Madrid, Spain (MAD) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or May, booked 72 days in advance, depart on a Monday or Sunday and return on a Sunday

Cheap flight deals from Madrid to Santiago

Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Air Canada deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/21:35 pm
MAD
-
SCL
2 stops50h 40m
Air Canada
Mon 2/168:55 pm
SCL
-
MAD
2 stops55h 05m
Air Canada
Deal found 1/29$794
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:45 pm
MAD
-
SCL
1 stop24h 30m
Delta
Sun 4/268:40 pm
SCL
-
MAD
1 stop33h 35m
Delta
Deal found 1/27$829
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/311:15 am
MAD
-
SCL
1 stop24h 25m
Delta
Mon 2/1611:10 pm
SCL
-
MAD
2 stops28h 50m
Delta
Deal found 1/27$830
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/310:00 am
MAD
-
SCL
2 stops49h 40m
Delta
Sun 2/1511:10 pm
SCL
-
MAD
1 stop30h 05m
Delta
Deal found 1/28$834
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:45 pm
MAD
-
SCL
1 stop24h 30m
Delta
Tue 4/288:40 pm
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 1/28$836
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/311:15 am
MAD
-
SCL
1 stop24h 25m
Delta
Thu 2/1911:10 pm
SCL
-
MAD
1 stop30h 05m
Delta
Deal found 1/29$837
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:50 am
MAD
-
SCL
1 stop27h 25m
Delta
Sun 10/188:40 pm
SCL
-
MAD
1 stop34h 35m
Delta
Deal found 1/29$839
This Air Canada deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/51:35 pm
MAD
-
SCL
1 stop21h 15m
Air Canada
Wed 2/188:55 pm
SCL
-
MAD
2 stops31h 05m
Air Canada
Deal found 1/27$844
This Air Canada deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/51:35 pm
MAD
-
SCL
1 stop21h 15m
Air Canada
Tue 2/178:55 pm
SCL
-
MAD
2 stops31h 05m
Air Canada
Deal found 1/28$847
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/110:00 am
MAD
-
SCL
2 stops25h 40m
Delta
Sun 2/1511:10 pm
SCL
-
MAD
2 stops38h 30m
Delta
Deal found 1/27$850
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/210:00 am
MAD
-
SCL
2 stops25h 40m
Delta
Sun 2/1511:10 pm
SCL
-
MAD
2 stops38h 30m
Delta
Deal found 1/27$854
This British Airways deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:50 am
MAD
-
SCL
1 stop31h 35m
British Airways
Fri 11/131:05 pm
SCL
-
MAD
1 stop18h 50m
British Airways
Deal found 1/27$861

Find flight deals from Madrid to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$829
(Delta)

One-way from

$540
(FlightHub)

Popular in

July

Cheapest in

March

Average price

$1,035

Good round-trip deal

$1,347 or less

Good one-way deal

$596 or less
Provider with most accurate pricing for Madrid Barajas-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Madrid Barajas-Santiago Arturo Merino Benitez flights.
Search Deals
From Madrid Barajas to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Madrid Barajas to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($142 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Madrid Barajas to Santiago Arturo Merino Benitez.
Search Deals
Price to beat on a one-way flight from Madrid Barajas to Santiago Arturo Merino Benitez.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Madrid

Fly to

Santiago

Route

Depart

Return

Price

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 4/16

12:45 pm-7:15 am

1 stop24h 30m

Santiago Arturo Merino Benitez

Sun 4/26

8:40 pm-12:15 pm

1 stop33h 35m

$829

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 4/13

2:35 pm-7:15 am

2 stops46h 40m

Santiago Arturo Merino Benitez

Tue 4/28

8:40 pm-9:55 am

2 stops31h 15m

$836

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 4/13

2:35 pm-7:15 am

2 stops46h 40m

Santiago Arturo Merino Benitez

Sun 4/26

8:40 pm-9:55 am

2 stops31h 15m

$836

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 4/16

12:45 pm-7:15 am

1 stop24h 30m

Santiago Arturo Merino Benitez

Wed 4/29

8:40 pm-9:55 am

2 stops55h 15m

$836

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 5/6

5:30 pm-1:25 pm

1 stop25h 55m

Santiago Arturo Merino Benitez

Fri 5/15

2:30 pm-2:05 pm

1 stop17h 35m

$886

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 4/13

2:35 pm-7:15 am

2 stops46h 40m

Santiago Arturo Merino Benitez

Mon 4/27

8:40 pm-9:55 am

2 stops31h 15m

$890

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 4/14

2:35 pm-7:15 am

2 stops46h 40m

Santiago Arturo Merino Benitez

Mon 4/27

8:40 pm-9:55 am

2 stops31h 15m

$890

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 2/8

10:00 am-7:40 am

2 stops25h 40m

Santiago Arturo Merino Benitez

Fri 3/6

11:10 pm-7:00 am

2 stops51h 50m

$897

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 3/12

6:00 am-7:50 am

2 stops29h 50m

Santiago Arturo Merino Benitez

Mon 3/16

9:45 pm-9:15 am

2 stops31h 30m

$911

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 4/15

12:45 pm-7:15 am

1 stop24h 30m

Santiago Arturo Merino Benitez

Wed 4/29

8:40 pm-12:15 pm

1 stop33h 35m

$937

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 21 results
1
2
3
  • Most accurate provider: When it comes to deals on Madrid-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Madrid-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Madrid-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Madrid-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Madrid to Santiago. Price data was last updated on January 23, 2026.

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 72 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of $516). Flying from Madrid to Santiago in July is currently the most expensive (average of $958). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

It’s optimal to fly from Madrid to Santiago in the afternoon. By choosing this option you can save up to 47% on the cost of your flight, compared to a flight in the evening.

How much does it cost to fly round-trip from Madrid to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown LATAM Airlines and Iberia from Madrid to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,918 reviews

Boarding

7.5

Crew

8.0

Entertainment

7.0

Overall

7.5

Comfort

7.3

Food

6.7

Reviews

1 / 20
2.0
Mediocre

JC,Jan 2026

FLN - GRU

Plane was late in FLN and missed connection in GRU. No alternative was given to me until 6 hours later and I was delayed by over 12 hours total.
LATAM Airlines
7.5
Good
1,918 reviews
LATAM Airlines
7.5
Good
1,918 reviews

Boarding

7.5

Crew

8.0

Entertainment

7.0

Overall

7.5

Comfort

7.3

Food

6.7

Reviews

1 / 20
2.0
Mediocre

JC,Jan 2026

FLN - GRU

Plane was late in FLN and missed connection in GRU. No alternative was given to me until 6 hours later and I was delayed by over 12 hours total.
Iberia
7.0
Good
3,100 reviews
LATAM Airlines
7.5
Good
1,918 reviews

Boarding

7.5

Crew

8.0

Entertainment

7.0

Overall

7.5

Comfort

7.3

Food

6.7

Reviews

1 / 20
2.0
Mediocre

JC,Jan 2026

FLN - GRU

Plane was late in FLN and missed connection in GRU. No alternative was given to me until 6 hours later and I was delayed by over 12 hours total.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Madrid to Santiago?

    Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Madrid Barajas. Booking flights from Barajas (MAD) to Arturo Merino Benitez (SCL) should be relatively easy as there are 12 daily flights to Santiago from 2 different airlines. 13h 15m is how long a flight from Madrid to Santiago Arturo Merino Benitez will take if you book a nonstop flight.

  • How long is the flight from Madrid to Santiago?

    A quick flight from Madrid to Santiago can take about 24h 30m. Delta provides one of the quickest options available for as low as $829. Airlines will cover a distance of 6656 mi.

  • What are the cheapest airlines flying from Madrid to Santiago round-trip?

    Our cheapest airline available from Madrid to Santiago is Iberia. Our recent data shows that you can find tickets from as low as $756 on this airline. An additional option worth looking into is LATAM Airlines, starting at $910. Iberia is priced at 31% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Madrid to Santiago one-way?

    One-way options have recently been found by users for as low as $420 on Iberia. Other airlines that offer cheap prices include Avianca from $474 and LATAM Airlines from $570 one-way.

  • What are the most reliable airlines from Madrid to Santiago?

    Consider Japan Airlines (88%), Finnair (88%) or EL AL (88%) when booking your flight. These represent the most reliable airlines when flying from Madrid to Santiago.

  • What are the cheapest flights from Madrid to Santiago?

    Looking at all options, your cheapest flight can be booked for $584. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for $886 on average, our data indicates $1,499 when flying from Madrid to Santiago.

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of $516). Flying from Madrid to Santiago in July is currently the most expensive (average of $958). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
Lastarria car rentals

Top 2 airlines flying from Madrid to Santiago

Discover the top 2 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest$756Average$1,193FlexibilityNo cancel feeOn-time77%
LATAM AirlinesCheapest$910Average$1,284FlexibilityNo cancel feeOn-time81%

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