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$493+ Cheap flights from Madrid, Spain (MAD) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or April, booked 88 days in advance, depart on a Tuesday or Sunday and return on a Wednesday

Cheap flight deals from Madrid to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$865
(Iberia)

One-way from

$493
(United Airlines)

Popular in

December

Cheapest in

March

Average price

$1,061

Good round-trip deal

$1,240 or less

Good one-way deal

$687 or less
From Madrid Barajas to Santiago Arturo Merino Benitez
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One-way flight from Madrid Barajas to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 5% potential increase in price ($59 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($27 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Madrid Barajas to Santiago Arturo Merino Benitez.
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Price to beat on a one-way flight from Madrid Barajas to Santiago Arturo Merino Benitez.
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Find flight deals from Madrid to Santiago

Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/211:05 amMAD - SCL
1 stop24h 35mDelta
Sat 11/811:10 pmSCL - MAD
1 stop30h 05mDelta
Deal found 9/15$867
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:05 amMAD - SCL
2 stops49h 45mUnited Airlines
Sun 12/710:45 pmSCL - MAD
2 stops53h 20mUnited Airlines
Deal found 9/16$869
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3010:00 amMAD - SCL
2 stops25h 40mDelta
Sun 11/2311:10 pmSCL - MAD
2 stops40h 00mDelta
Deal found 9/17$870
This British Airways deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1611:45 amMAD - SCL
1 stop28h 45mBritish Airways
Tue 10/281:05 pmSCL - MAD
1 stop18h 50mBritish Airways
Deal found 9/15$871
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/411:15 amMAD - SCL
1 stop24h 25mDelta
Mon 11/1711:10 pmSCL - MAD
1 stop30h 05mDelta
Deal found 9/17$873
This LATAM Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1711:05 amMAD - SCL
Nonstop13h 25mLATAM Airlines
Sun 11/301:40 pmSCL - MAD
1 stop22h 45mLATAM Airlines
Deal found 9/15$874
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:00 amMAD - SCL
2 stops29h 40mDelta
Sun 11/2311:10 pmSCL - MAD
2 stops32h 20mDelta
Deal found 9/15$875
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:00 amMAD - SCL
2 stops29h 40mDelta
Tue 11/2511:10 pmSCL - MAD
2 stops32h 20mDelta
Deal found 9/16$876
This Iberia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/177:10 pmMAD - SCL
1 stop19h 00mIberia
Tue 12/1611:55 pmSCL - MAD
Nonstop12h 40mIberia
Deal found 9/17$878
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1011:15 amMAD - SCL
1 stop24h 25mDelta
Sun 1/1811:15 pmSCL - MAD
1 stop29h 45mDelta
Deal found 9/15$880
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:00 amMAD - SCL
2 stops48h 10mDelta
Thu 1/2911:15 pmSCL - MAD
2 stops28h 45mDelta
Deal found 9/16$881
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1211:15 amMAD - SCL
1 stop24h 25mDelta
Sun 1/1811:15 pmSCL - MAD
1 stop29h 45mDelta
Deal found 9/16$885

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Madrid

Fly to

Santiago

Route

Depart

Return

Price

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 11/10

6:00 am-7:40 am

2 stops29h 40m

Santiago Arturo Merino Benitez

Sun 11/23

11:10 pm-5:40 pm

2 stops38h 30m

$867

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 11/11

6:00 am-7:40 am

2 stops29h 40m

Santiago Arturo Merino Benitez

Tue 11/25

11:10 pm-7:10 pm

2 stops40h 00m

$881

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 1/14

10:00 am-6:10 am

2 stops48h 10m

Santiago Arturo Merino Benitez

Sun 1/25

11:15 pm-8:00 am

2 stops28h 45m

$886

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 1/14

10:00 am-6:10 am

2 stops48h 10m

Santiago Arturo Merino Benitez

Wed 1/21

11:15 pm-8:00 am

2 stops28h 45m

$886

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 11/5

10:00 am-7:40 am

2 stops25h 40m

Santiago Arturo Merino Benitez

Sat 11/15

11:10 pm-9:15 am

1 stop30h 05m

$886

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Fri 10/31

6:00 am-7:40 am

2 stops29h 40m

Santiago Arturo Merino Benitez

Fri 11/7

11:10 pm-9:15 am

1 stop30h 05m

$903

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 12/7

6:00 am-7:40 am

2 stops29h 40m

Santiago Arturo Merino Benitez

Sat 1/24

9:30 pm-8:00 am

2 stops30h 30m

$904

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 1/13

10:00 am-7:00 am

2 stops25h 00m

Santiago Arturo Merino Benitez

Sun 1/25

11:15 pm-8:00 am

2 stops28h 45m

$945

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 11/17

6:00 am-7:40 am

2 stops29h 40m

Santiago Arturo Merino Benitez

Sun 11/30

11:10 pm-12:10 pm

2 stops33h 00m

$953

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 11/13

11:15 am-7:40 am

1 stop24h 25m

Santiago Arturo Merino Benitez

Sat 3/21

11:15 pm-10:15 am

2 stops31h 00m

$986

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 20 results
1
2

Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Madrid to Santiago. Price data was last updated on September 12, 2025.

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, April is the cheapest month in which you can book a flight from Madrid to Santiago (average of $752). Flying from Madrid to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

It’s optimal to fly from Madrid to Santiago at noon. By choosing this option you can save up to 13% on the cost of your flight, compared to a flight in the morning.

How much does it cost to fly round-trip from Madrid to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown LATAM Airlines, Iberia, and Avianca from Madrid to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,849 reviews

Boarding

7.6

Crew

8.0

Overall

7.5

Food

6.7

Comfort

7.4

Entertainment

7.0

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.
LATAM Airlines
7.5
Good
1,849 reviews
LATAM Airlines
7.5
Good
1,849 reviews

Boarding

7.6

Crew

8.0

Overall

7.5

Food

6.7

Comfort

7.4

Entertainment

7.0

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.
Iberia
7.0
Good
2,925 reviews
LATAM Airlines
7.5
Good
1,849 reviews

Boarding

7.6

Crew

8.0

Overall

7.5

Food

6.7

Comfort

7.4

Entertainment

7.0

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.
Avianca
6.7
Okay
2,436 reviews
LATAM Airlines
7.5
Good
1,849 reviews

Boarding

7.6

Crew

8.0

Overall

7.5

Food

6.7

Comfort

7.4

Entertainment

7.0

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.
British Airways
6.7
Okay
7,367 reviews
LATAM Airlines
7.5
Good
1,849 reviews

Boarding

7.6

Crew

8.0

Overall

7.5

Food

6.7

Comfort

7.4

Entertainment

7.0

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Madrid to Santiago?

    Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Madrid Barajas. Booking flights from Barajas (MAD) to Arturo Merino Benitez (SCL) should be relatively easy as there are 14 daily flights to Santiago from 4 different airlines. 13h 15m is how long a flight from Madrid to Santiago Arturo Merino Benitez will take if you book a nonstop flight.

  • How long is the flight from Madrid to Santiago?

    A quick flight from Madrid to Santiago can take about 29h 40m. Delta provides one of the quickest options available for as low as $867. Airlines will cover a distance of 6656 mi.

  • What are the cheapest airlines flying from Madrid to Santiago round-trip?

    Our cheapest airline available from Madrid to Santiago is Iberia. Our recent data shows that you can find tickets from as low as $706 on this airline. Additional options worth looking into are British Airways and LATAM Airlines, starting at $714 and $719 round-trip. Iberia is priced at 34% lower than the current average price of a flight leaving 3 months from now.

  • What are the most reliable airlines from Madrid to Santiago?

    Consider Finnair (95%), Japan Airlines (92%) or EL AL (92%) when booking your flight. These represent the most reliable airlines when flying from Madrid to Santiago.

  • What are the cheapest flights from Madrid to Santiago?

    Looking at all options, your cheapest flight can be booked for $582. While the most popular route (Madrid Barajas - Santiago Arturo Merino Benitez) can be booked for $821 on average, our data indicates $1,140 when flying from Madrid to Santiago.

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Madrid to Santiago (average of $752). Flying from Madrid to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
Temuco car rentals
Lastarria car rentals

Top 4 airlines flying from Madrid to Santiago

Discover the top 4 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest$706Average$1,122FlexibilityNo cancel feeOn-time77%
British AirwaysCheapest$714Average$968FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$719Average$1,319FlexibilityNo cancel feeOn-time81%
AviancaCheapest$804Average$1,427FlexibilityNo cancel feeOn-time71%

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