$355+ Cheap flights from Madrid, Spain (MAD) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
mag 16 — mag 231
Round-trip
1 adult, Economy
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Find cheap flights from Madrid to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or May, booked 72 days in advance, depart on a Thursday or Sunday and return on a Sunday
Cheap flight deals from Madrid to Santiago
Cheapest
Best
Last-minute
One-way
Cheapest flights from Madrid to SantiagoExplore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on aprile 16, 2026.
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on aprile 16, 2026.
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 9/142:35 pm
MAD
- SCL
2 stops46h 40m
Delta
mer 9/308:40 pm
SCL
- MAD
2 stops41h 55m
Delta
Deal found 4/11![Delta logo]()
$862
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/2112:45 pm
MAD
- SCL
2 stops24h 30m
Delta
gio 5/288:40 pm
SCL
- MAD
2 stops33h 30m
Delta
Deal found 4/12![Delta logo]()
$863
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 5/119:50 am
MAD
- SCL
1 stop27h 25m
Delta
gio 5/288:40 pm
SCL
- MAD
2 stops33h 30m
Delta
Deal found 4/12![Delta logo]()
$864
This Booking.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/71:15 pm
MAD
- SCL
Nonstop13h 20m
LATAM Airlines
dom 7/57:00 pm
SCL
- MAD
Nonstop12h 55m
LATAM Airlines
Deal found 4/14![LATAM Airlines logo]()
$865
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 10/2910:00 am
MAD
- SCL
2 stops25h 40m
Delta
mar 11/1711:10 pm
SCL
- MAD
2 stops34h 10m
Delta
Deal found 4/15![Delta logo]()
$867
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 9/169:50 am
MAD
- SCL
1 stop27h 25m
Delta
dom 10/48:40 pm
SCL
- MAD
1 stop34h 35m
Delta
Deal found 4/13![Delta logo]()
$870
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 10/296:00 am
MAD
- SCL
2 stops29h 40m
Delta
gio 11/1211:10 pm
SCL
- MAD
2 stops38h 30m
Delta
Deal found 4/15![Delta logo]()
$871
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 11/511:55 am
MAD
- SCL
1 stop23h 45m
Delta
dom 11/1511:10 pm
SCL
- MAD
1 stop30h 45m
Delta
Deal found 4/14![Delta logo]()
$880
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 5/1112:45 pm
MAD
- SCL
2 stops48h 30m
Delta
dom 5/318:40 pm
SCL
- MAD
2 stops51h 40m
Delta
Deal found 4/13![Delta logo]()
$881
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 11/410:00 am
MAD
- SCL
2 stops49h 40m
Delta
mar 12/111:10 pm
SCL
- MAD
2 stops28h 50m
Delta
Deal found 4/12![Delta logo]()
$882
Best flights from Madrid to SantiagoDiscover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated aprile 16, 2026.
Discover carefully curated flight deals from Madrid to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated aprile 16, 2026.
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 9/169:50 am
MAD
- SCL
1 stop27h 25m
Delta
mer 9/308:40 pm
SCL
- MAD
2 stops41h 55m
Delta
Deal found 4/11![Delta logo]()
$862
This Turkish Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 5/136:25 pm
MAD
- SCL
3 stops40h 45m
Multiple Airlines
mer 5/2711:17 am
SCL
- MAD
2 stops44h 18m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$888
This Turkish Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 6/1212:00 pm
MAD
- SCL
3 stops47h 03m
Turkish Airlines
mar 7/2810:15 am
SCL
- MAD
2 stops42h 10m
Turkish Airlines
Deal found 4/16![Turkish Airlines logo]()
$911
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 8/279:50 am
MAD
- SCL
1 stop27h 25m
Delta
mar 10/68:40 pm
SCL
- MAD
2 stops28h 40m
Delta
Deal found 4/13![Delta logo]()
$881
This Turkish Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 8/277:40 am
MAD
- SCL
3 stops51h 23m
Multiple Airlines
lun 10/53:57 am
SCL
- MAD
2 stops37h 38m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$900
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 5/412:45 pm
MAD
- SCL
1 stop24h 30m
Delta
dom 5/248:40 pm
SCL
- MAD
2 stops27h 40m
Delta
Deal found 4/15![Delta logo]()
$945
This Turkish Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 5/267:40 am
MAD
- SCL
3 stops51h 30m
Multiple Airlines
mar 6/211:17 am
SCL
- MAD
2 stops29h 18m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$1,013
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 9/89:50 am
MAD
- SCL
1 stop27h 25m
Delta
mer 9/238:40 pm
SCL
- MAD
1 stop34h 35m
Delta
Deal found 4/14![Delta logo]()
$986
This Turkish Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 6/122:40 pm
MAD
- SCL
3 stops44h 23m
Multiple Airlines
mar 7/289:15 am
SCL
- MAD
3 stops43h 10m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$1,077
Last-minute flights from Madrid to SantiagoDiscover last-minute flight deals from Madrid to Santiago. Data last updated aprile 16, 2026 and is based on user searches.
Discover last-minute flight deals from Madrid to Santiago. Data last updated aprile 16, 2026 and is based on user searches.
This Turkish Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 4/222:40 pm
MAD
- SCL
3 stops44h 30m
Multiple Airlines
lun 5/411:17 am
SCL
- MAD
2 stops47h 38m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$890
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 5/212:45 pm
MAD
- SCL
1 stop24h 30m
Delta
lun 5/118:40 pm
SCL
- MAD
2 stops27h 40m
Delta
Deal found 4/14![Delta logo]()
$880
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 5/412:45 pm
MAD
- SCL
1 stop24h 30m
Delta
lun 6/18:40 pm
SCL
- MAD
2 stops27h 40m
Delta
Deal found 4/12![Delta logo]()
$882
This Avianca deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 5/411:05 am
MAD
- SCL
1 stop23h 40m
Avianca
dom 5/243:20 pm
SCL
- MAD
1 stop16h 45m
Avianca
Deal found 4/13![Avianca logo]()
$889
This Booking.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/71:15 pm
MAD
- SCL
Nonstop13h 20m
LATAM Airlines
dom 7/57:00 pm
SCL
- MAD
Nonstop12h 55m
LATAM Airlines
Deal found 4/14![LATAM Airlines logo]()
$865
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 5/119:50 am
MAD
- SCL
1 stop27h 25m
Delta
gio 5/288:40 pm
SCL
- MAD
2 stops33h 30m
Delta
Deal found 4/12![Delta logo]()
$864
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 5/119:50 am
MAD
- SCL
1 stop27h 25m
Delta
dom 5/318:40 pm
SCL
- MAD
2 stops51h 40m
Delta
Deal found 4/13![Delta logo]()
$881
This Avianca deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 5/1111:05 am
MAD
- SCL
1 stop18h 15m
Avianca
gio 5/286:40 am
SCL
- MAD
1 stop20h 25m
Avianca
Deal found 4/14![Avianca logo]()
$888
This Turkish Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 5/117:40 am
MAD
- SCL
3 stops51h 30m
Multiple Airlines
mer 5/274:41 am
SCL
- MAD
2 stops50h 54m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$891
This Avianca deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 5/135:20 pm
MAD
- SCL
1 stop17h 25m
Avianca
mer 5/276:40 am
SCL
- MAD
1 stop17h 30m
Avianca
Deal found 4/12![Avianca logo]()
$886
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/2112:45 pm
MAD
- SCL
2 stops24h 30m
Delta
gio 5/288:40 pm
SCL
- MAD
2 stops33h 30m
Delta
Deal found 4/12![Delta logo]()
$863
One-way flights from Madrid to SantiagoSearch for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated aprile 16, 2026.
Search for one-way flight options from Madrid to Santiago. Find affordable one-way fares based on user searches. Data last updated aprile 16, 2026.
This Avianca deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 4/298:10 am
MAD
- SCL
1 stop21h 10m
Avianca
Deal found 4/12![Avianca logo]()
$355
This Avianca deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/18:10 am
MAD
- SCL
1 stop21h 10m
Avianca
Deal found 4/13![Avianca logo]()
$356
This Trip.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 4/291:15 pm
MAD
- SCL
Nonstop13h 20m
LATAM Airlines
Deal found 4/12![LATAM Airlines logo]()
$369
This Trip.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 5/121:15 pm
MAD
- SCL
Nonstop13h 20m
LATAM Airlines
Deal found 4/15![LATAM Airlines logo]()
$370
This Trip.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 5/131:15 pm
MAD
- SCL
Nonstop13h 20m
LATAM Airlines
Deal found 4/14![LATAM Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 4/2912:40 pm
MAD
- SCL
2 stops26h 05m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 5/116:35 am
MAD
- SCL
2 stops32h 10m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$390
This FlightHub deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 6/511:05 am
MAD
- SCL
1 stop18h 15m
Avianca
Deal found 4/14![Avianca logo]()
$397
This deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/172:20 am
MAD
- SCL
1 stop17h 55m
Avianca
Deal found 4/13![Avianca logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 5/136:25 am
MAD
- SCL
3 stops28h 20m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$404
This Trip.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 5/27:05 am
MAD
- SCL
2 stops37h 10m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$408
This LATAM Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 5/91:15 pm
MAD
- SCL
Nonstop13h 20m
LATAM Airlines
Deal found 4/14![LATAM Airlines logo]()
$440
Find flight deals from Madrid to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated aprile 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $862 (Delta) |
One-way from | $355 (Avianca) |
Popular in | July |
Cheapest in | March |
Average price | $1,035 |
Good one-way deal | $588 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated aprile 16, 2026.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
mer 9/16
9:50 am-8:15 am
1 stop27h 25m
Santiago Arturo Merino Benitez
mer 9/30
8:40 pm-7:35 pm
2 stops41h 55m
$862
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
gio 8/27
9:50 am-7:15 am
1 stop27h 25m
Santiago Arturo Merino Benitez
mar 10/6
8:40 pm-6:20 am
2 stops28h 40m
$881
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
mer 5/13
6:25 pm-5:10 am
3 stops40h 45m
Santiago Arturo Merino Benitez
mer 5/27
11:17 am-1:35 pm
2 stops44h 18m
$888
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
gio 8/27
7:40 am-5:03 am
3 stops51h 23m
Santiago Arturo Merino Benitez
lun 10/5
3:57 am-10:35 pm
2 stops37h 38m
$900
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
ven 6/12
12:00 pm-5:03 am
3 stops47h 03m
Santiago Arturo Merino Benitez
mar 7/28
10:15 am-10:25 am
2 stops42h 10m
$911
Quickest round-trip
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
lun 5/4
12:45 pm-7:15 am
1 stop24h 30m
Santiago Arturo Merino Benitez
dom 5/24
8:40 pm-6:20 am
2 stops27h 40m
$945
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
mar 9/8
9:50 am-8:15 am
1 stop27h 25m
Santiago Arturo Merino Benitez
mer 9/23
8:40 pm-12:15 pm
1 stop34h 35m
$986
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
mar 5/26
7:40 am-5:10 am
3 stops51h 30m
Santiago Arturo Merino Benitez
mar 6/2
11:17 am-10:35 pm
2 stops29h 18m
$1,013
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
ven 6/12
2:40 pm-5:03 am
3 stops44h 23m
Santiago Arturo Merino Benitez
mar 7/28
9:15 am-10:25 am
3 stops43h 10m
$1,077
Cheapest one-way
Quickest one-way
MadridSantiago
MAD - SCL
MADSCL
Madrid Barajas
dom 5/17
1:00 pm-8:20 pm
Nonstop13h 20m
$498
Showing 1-10 of 18 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Madrid-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Madrid-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Madrid-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Madrid-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Madrid to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
MAD-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Santiago
Prices
Airlines
Delays
How far ahead should I book a flight from Madrid to Santiago?
Use this chart to determine the optimal time to book a round-trip flight from Madrid to Santiago. Price data was last updated on April 10, 2026.
The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 72 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Santiago?
Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of $503). Flying from Madrid to Santiago in July is currently the most expensive (average of $1,085). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to SCL?
Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated aprile 16, 2026.
It’s optimal to fly from Madrid to Santiago in the afternoon. By choosing this option you can save up to 47% on the cost of your flight, compared to a flight in the evening.
How often are flights from Madrid to Santiago delayed?
About 15% of weekly flights between Madrid and Santiago have experienced delays in the past year, with the average delay time being 133 minutes.
What is the most punctual flight time for Madrid to Santiago flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Madrid to Santiago flights?
Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 12% of flights being delayed.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated aprile 16, 2026.
Read reviews from past customers who have flown LATAM Airlines,Iberia, andAvianca from Madrid to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Overall
7.4
Entertainment
7.0
Boarding
7.5
Crew
8.0
Food
6.7
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Comfort
7.3
Overall
7.4
Entertainment
7.0
Boarding
7.5
Crew
8.0
Food
6.7
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Comfort
7.3
Overall
7.4
Entertainment
7.0
Boarding
7.5
Crew
8.0
Food
6.7
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Comfort
7.3
Overall
7.4
Entertainment
7.0
Boarding
7.5
Crew
8.0
Food
6.7
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Related info for your journey
Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Find flights from Madrid to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Madrid and Santiago flights
Browse other Madrid and Santiago flight options. Last updated on aprile 16, 2026.
Other flights from Madrid
Browse through other flights departing from Madrid. Flights are based on user searches made on Cheapflights and were last updated on aprile 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on aprile 16, 2026.
Top 3 airlines flying from Madrid to Santiago
Discover the top 3 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated aprile 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$502 | Average$922 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$755 | Average$1,261 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$910 | Average$1,316 | FlexibilityNo cancel fee | On-time81% |