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$337+ Cheap flights from Indianapolis (IND) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
IND — SCL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Indianapolis to Santiago

Cheapest flights from Indianapolis to Santiago
Explore the most affordable flight options available from Indianapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:25 amIND - SCL
1 stop22h 20mAmerican Airlines
Sun 1/1810:35 pmSCL - IND
1 stop13h 26mAmerican Airlines
Deal found 12/11$894
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:45 pmIND - SCL
2 stops35h 05mUnited Airlines
Sun 1/1810:45 pmSCL - IND
1 stop19h 06mUnited Airlines
Deal found 12/11$914
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:48 amIND - SCL
1 stop20h 07mMultiple Airlines
Fri 1/912:45 amSCL - IND
2 stops46h 58mMultiple Airlines
Deal found 12/10$1,059
This KAYAK deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:00 amIND - SCL
2 stops20h 35mLATAM Airlines
Wed 12/3112:20 amSCL - IND
2 stops25h 52mLATAM Airlines
Deal found 12/11$1,186
This KAYAK deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:00 amIND - SCL
3 stops35h 50mLATAM Airlines
Sun 1/184:35 pmSCL - IND
2 stops27h 15mLATAM Airlines
Deal found 12/10$1,201
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:56 amIND - SCL
2 stops16h 39mDelta
Sat 1/1011:25 pmSCL - IND
2 stops26h 41mDelta
Deal found 12/10$1,517
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:21 amIND - SCL
2 stops20h 04mAmerican Airlines
Thu 1/111:55 pmSCL - IND
1 stop26h 04mAmerican Airlines
Deal found 12/11$1,714

Find flight deals from Indianapolis to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$732
(LATAM Airlines)

One-way from

$337
(Kiwi.com)

Popular in

October

Cheapest in

March

Average price

$1,389
Provider with most accurate pricing for Indianapolis-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Santiago Arturo Merino Benitez flights.
Search Deals
From Indianapolis to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Indianapolis to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($162 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($83 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Indianapolis to Santiago that are best for you.

Fly from

Indianapolis

Fly to

Santiago

Route

Depart

Return

Price

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Fri 12/26

7:25 am-7:45 am

1 stop22h 20m

Santiago Arturo Merino Benitez

Sun 1/18

10:35 pm-10:01 am

1 stop13h 26m

$894

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Thu 1/8

5:05 pm-8:50 am

1 stop13h 45m

Santiago Arturo Merino Benitez

Thu 1/15

10:45 pm-10:48 am

1 stop14h 03m

$942

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Mon 1/26

11:40 am-8:50 am

1 stop19h 10m

Santiago Arturo Merino Benitez

Thu 1/29

10:45 pm-3:51 pm

1 stop19h 06m

$972

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Fri 12/26

7:45 pm-8:50 am

2 stops35h 05m

Santiago Arturo Merino Benitez

Sun 1/18

10:45 pm-5:52 pm

2 stops21h 07m

$994

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Thu 1/8

6:55 am-6:40 am

3 stops21h 45m

Santiago Arturo Merino Benitez

Wed 1/14

1:35 am-10:48 pm

3 stops23h 13m

$997

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Mon 1/26

4:24 pm-7:40 am

1 stop13h 16m

Santiago Arturo Merino Benitez

Thu 1/29

11:10 pm-5:50 pm

1 stop20h 40m

$1,074

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Mon 2/2

8:26 pm-9:55 pm

2 stops47h 29m

$337

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Sat 1/31

8:26 pm-9:59 am

2 stops35h 33m

$359

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Mon 2/2

3:29 pm-8:15 am

1 stop14h 46m

$543

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Sat 1/31

2:30 pm-7:40 am

1 stop15h 10m

$581

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 11 results
1
2

Compare providers for flights from Indianapolis to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Santiago in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
OvagoPrice Accuracy2 starsTrust Score*2 stars
ExpediaPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Indianapolis-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Indianapolis-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Indianapolis-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Indianapolis-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Santiago

What is the cheapest month to book a flight from Indianapolis to Santiago?

Currently, November is the cheapest month in which you can book a flight from Indianapolis to Santiago (average of $549). Flying from Indianapolis to Santiago in June is currently the most expensive (average of $930). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to SCL?

Find hourly flight availability from Indianapolis to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from Indianapolis to Santiago is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 20% on airfare.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 12, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Indianapolis to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,889 reviews
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,008 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indianapolis to Santiago?

    A quick flight from Indianapolis to Santiago can take about 13h 45m. American Airlines provides one of the quickest options available for as low as $942. The distance between Indianapolis and Santiago is about 5144 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Indianapolis to Santiago round-trip?

    According to our current data, LATAM Airlines ($811), Delta ($842), and American Airlines ($864) offers the cheapest pricing from Indianapolis to Santiago. LATAM Airlines is 28% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Indianapolis to Santiago that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Santiago.

  • Can I find deals for business class flights from Indianapolis to Santiago?

    Yes. Cheapflights offers flight deals from Indianapolis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Indianapolis to Santiago (average of $549). Flying from Indianapolis to Santiago in June is currently the most expensive (average of $930). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Indianapolis to Santiago

Discover the top 3 airlines that operate flights from Indianapolis to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$811Average$1,015FlexibilityNo cancel feeOn-time81%
DeltaCheapest$842Average$1,039FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$864Average$1,169FlexibilityNo cancel feeOn-time71%

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