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$662+ Cheap flights from Indianapolis (IND) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
IND — SCL
nov. 27 — dic. 41
jue. 11/27
jue. 12/4
1 adult, Economy
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Find flight deals from Indianapolis to Santiago

Cheapest flights from Indianapolis to Santiago
Explore the most affordable flight options available from Indianapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 28, 2025.

This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/197:00 amIND - SCL
3 stops21h 25mMultiple Airlines
lun. 12/19:10 pmSCL - IND
3 stops25h 58mMultiple Airlines
Deal found 10/26$662
This LATAM Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/912:57 pmIND - SCL
1 stop15h 58mLATAM Airlines
mar. 12/1611:25 pmSCL - IND
2 stops15h 43mLATAM Airlines
Deal found 10/28$720
This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/34:48 pmIND - SCL
1 stop12h 52mLATAM Airlines
lun. 11/1711:30 pmSCL - IND
1 stop14h 46mLATAM Airlines
Deal found 10/26$748
This eDestinos deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/1912:56 pmIND - SCL
1 stop15h 59mLATAM Airlines
lun. 12/111:10 pmSCL - IND
1 stop13h 18mLATAM Airlines
Deal found 10/26$754
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/182:20 pmIND - SCL
2 stops16h 30mUnited Airlines
lun. 12/110:45 pmSCL - IND
2 stops20h 59mUnited Airlines
Deal found 10/26$761
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/31:41 pmIND - SCL
2 stops17h 19mAmerican Airlines
lun. 11/1710:25 pmSCL - IND
2 stops17h 41mAmerican Airlines
Deal found 10/26$769
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/207:00 amIND - SCL
3 stops29h 40mMultiple Airlines
lun. 12/112:30 pmSCL - IND
3 stops34h 38mMultiple Airlines
Deal found 10/26$775
This Expedia deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2010:05 amIND - SCL
1 stop19h 35mLATAM Airlines
lun. 12/110:25 pmSCL - IND
2 stops28h 01mLATAM Airlines
Deal found 10/26$789

Cheap flight deals from Indianapolis to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated octubre 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$662
(Mytrip)

Popular in

December

Cheapest in

October

Average price

$847
Provider with most accurate pricing for Indianapolis-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Santiago Arturo Merino Benitez flights.
Search Deals
From Indianapolis to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($79 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 28, 2025.
Use the filters below to find and compare flights from Indianapolis to Santiago that are best for you.

Fly from

Indianapolis

Fly to

Santiago

Route

Depart

Return

Price

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

mar. 12/9

12:57 pm-6:55 am

1 stop15h 58m

Santiago Arturo Merino Benitez

mar. 12/16

11:25 pm-1:08 pm

2 stops15h 43m

$720

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

mar. 11/25

6:45 am-8:50 am

1 stop24h 05m

Santiago Arturo Merino Benitez

mar. 12/2

10:45 pm-10:53 am

1 stop14h 08m

$761

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

jue. 11/20

6:00 am-7:40 am

1 stop23h 40m

Santiago Arturo Merino Benitez

mar. 12/2

11:30 pm-4:06 pm

1 stop18h 36m

$761

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

lun. 11/24

5:22 pm-8:50 am

1 stop13h 28m

Santiago Arturo Merino Benitez

lun. 12/1

10:45 pm-8:04 pm

1 stop23h 19m

$761

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

jue. 11/20

6:00 am-7:40 am

1 stop23h 40m

Santiago Arturo Merino Benitez

lun. 12/1

11:10 pm-10:28 am

1 stop13h 18m

$761

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

lun. 11/24

11:45 am-8:50 am

1 stop19h 05m

Santiago Arturo Merino Benitez

mar. 12/2

10:45 pm-3:46 pm

1 stop19h 01m

$761

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

mar. 11/18

5:22 pm-8:50 am

1 stop13h 28m

Santiago Arturo Merino Benitez

lun. 12/1

10:45 pm-1:33 pm

2 stops16h 48m

$761

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

lun. 3/2

11:41 am-6:35 am

2 stops16h 54m

$1,501

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

lun. 3/2

9:00 am-8:50 am

1 stop21h 50m

$2,118

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Compare providers for flights from Indianapolis to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Santiago in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Indianapolis-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Indianapolis-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Indianapolis-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Indianapolis-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Santiago

What is the cheapest month to book a flight from Indianapolis to Santiago?

Currently, November is the cheapest month in which you can book a flight from Indianapolis to Santiago (average of $549). Flying from Indianapolis to Santiago in June is currently the most expensive (average of $930). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to SCL?

Find hourly flight availability from Indianapolis to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 28, 2025.

One of the essential ways to save on airfare from Indianapolis to Santiago is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 20% on airfare.

How much does it cost to fly round-trip from Indianapolis to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated octubre 28, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Indianapolis to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,995 reviews

Overall

7.9

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,995 reviews
Delta
7.9
Good
7,995 reviews

Overall

7.9

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
LATAM Airlines
7.5
Good
1,871 reviews
Delta
7.9
Good
7,995 reviews

Overall

7.9

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,995 reviews

Overall

7.9

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indianapolis to Santiago?

    A quick flight from Indianapolis to Santiago can take about 15h 58m. LATAM Airlines provides one of the quickest options available for as low as $720. The distance between Indianapolis and Santiago is about 5144 mi.

  • What are the cheapest airlines flying from Indianapolis to Santiago round-trip?

    According to our current data, Delta ($693), LATAM Airlines ($811), and American Airlines ($864) offers the cheapest pricing from Indianapolis to Santiago. Delta is 30% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Indianapolis to Santiago that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Santiago.

  • Can I find deals for business class flights from Indianapolis to Santiago?

    Yes. Cheapflights offers flight deals from Indianapolis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Indianapolis to Santiago (average of $549). Flying from Indianapolis to Santiago in June is currently the most expensive (average of $930). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Indianapolis to Santiago

Discover the top 3 airlines that operate flights from Indianapolis to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$693Average$1,006FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$811Average$979FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$864Average$1,199FlexibilityNo cancel feeOn-time71%

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