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$417+ Cheap flights from Indianapolis (IND) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
IND — SCL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Indianapolis to Santiago

Cheapest flights from Indianapolis to Santiago
Explore the most affordable flight options available from Indianapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:00 am
IND
-
SCL
3 stops41h 30m
Multiple Airlines
Tue 3/2412:35 pm
SCL
-
IND
3 stops35h 40m
Multiple Airlines
Deal found 1/27$668
This LATAM Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:52 pm
IND
-
SCL
1 stop17h 58m
LATAM Airlines
Tue 6/308:40 pm
SCL
-
IND
1 stop16h 08m
LATAM Airlines
Deal found 1/28$790
This Mytrip deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/93:12 pm
IND
-
SCL
3 stops35h 48m
Multiple Airlines
Mon 3/167:25 am
SCL
-
IND
3 stops40h 50m
Multiple Airlines
Deal found 1/28$806
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1712:16 pm
IND
-
SCL
1 stop16h 39m
LATAM Airlines
Tue 3/2410:40 pm
SCL
-
IND
1 stop14h 33m
LATAM Airlines
Deal found 1/27$821
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:18 pm
IND
-
SCL
2 stops30h 56m
Multiple Airlines
Tue 3/1710:40 pm
SCL
-
IND
1 stop25h 35m
Multiple Airlines
Deal found 1/29$835
This KAYAK deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/912:16 pm
IND
-
SCL
1 stop16h 39m
LATAM Airlines
Mon 3/165:15 am
SCL
-
IND
2 stops20h 05m
LATAM Airlines
Deal found 1/29$839

Find flight deals from Indianapolis to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$668
(Mytrip)

One-way from

$417
(American Airlines)

Popular in

February

Cheapest in

March

Average price

$1,119
Provider with most accurate pricing for Indianapolis-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Santiago Arturo Merino Benitez flights.
Search Deals
From Indianapolis to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Indianapolis to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($41 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Indianapolis to Santiago that are best for you.

Fly from

Indianapolis

Fly to

Santiago

Route

Depart

Return

Price

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Tue 3/17

6:00 am-12:30 am

3 stops41h 30m

Santiago Arturo Merino Benitez

Tue 3/24

12:35 pm-11:15 pm

3 stops35h 40m

$668

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Mon 3/9

3:12 pm-4:00 am

3 stops35h 48m

Santiago Arturo Merino Benitez

Mon 3/16

7:25 am-11:15 pm

3 stops40h 50m

$806

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Tue 3/17

12:16 pm-5:55 am

1 stop16h 39m

Santiago Arturo Merino Benitez

Tue 3/24

10:40 pm-12:13 pm

1 stop14h 33m

$821

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Mon 3/2

6:22 pm-2:05 pm

2 stops17h 43m

Santiago Arturo Merino Benitez

Tue 3/17

10:40 pm-12:13 pm

1 stop14h 33m

$839

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Mon 3/9

12:16 pm-5:55 am

1 stop16h 39m

Santiago Arturo Merino Benitez

Mon 3/16

5:15 am-12:20 am

2 stops20h 05m

$839

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Wed 3/11

12:16 pm-5:55 am

1 stop16h 39m

Santiago Arturo Merino Benitez

Wed 3/18

12:20 am-5:58 pm

2 stops18h 38m

$858

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Tue 3/10

12:16 pm-5:55 am

1 stop16h 39m

Santiago Arturo Merino Benitez

Tue 3/17

11:55 pm-4:18 pm

1 stop17h 23m

$858

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Mon 3/2

7:37 am-8:05 am

1 stop22h 28m

$417

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Sun 2/15

6:10 pm-8:50 am

2 stops36h 40m

$490

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Mon 3/2

1:44 pm-2:30 pm

3 stops22h 46m

$828

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Compare providers for flights from Indianapolis to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Santiago in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Indianapolis-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Indianapolis-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Indianapolis-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Indianapolis-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Santiago

What is the cheapest month to book a flight from Indianapolis to Santiago?

Currently, November is the cheapest month in which you can book a flight from Indianapolis to Santiago (average of $549). Flying from Indianapolis to Santiago in June is currently the most expensive (average of $930). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Indianapolis to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated January 29, 2026.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Indianapolis to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,128 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,917 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,205 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Indianapolis to Santiago round-trip?

    According to our current data, LATAM Airlines ($803), Delta ($844), and American Airlines ($864) offers the cheapest pricing from Indianapolis to Santiago. LATAM Airlines is 29% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Indianapolis to Santiago that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Santiago.

  • Can I find deals for business class flights from Indianapolis to Santiago?

    Yes. Cheapflights offers flight deals from Indianapolis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Indianapolis to Santiago (average of $549). Flying from Indianapolis to Santiago in June is currently the most expensive (average of $930). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Indianapolis to Santiago

Discover the top 3 airlines that operate flights from Indianapolis to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$803Average$1,026FlexibilityNo cancel feeOn-time81%
DeltaCheapest$844Average$1,063FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$864Average$1,164FlexibilityNo cancel feeOn-time71%

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