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$282+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SCL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Detroit to Santiago

Cheapest flights from Detroit to Santiago
Explore the most affordable flight options available from Detroit to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:00 amDTW - SCL
2 stops21h 25mAmerican Airlines
Mon 12/2911:55 pmSCL - DTW
2 stops18h 34mAmerican Airlines
Deal found 12/11$919
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:35 amDTW - SCL
1 stop25h 50mAmerican Airlines
Wed 12/3111:15 pmSCL - DTW
1 stop25h 42mAmerican Airlines
Deal found 12/11$987
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amDTW - SCL
2 stops24h 50mUnited Airlines
Mon 12/2910:45 pmSCL - DTW
2 stops20h 32mUnited Airlines
Deal found 12/10$1,089
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:35 amDTW - SCL
1 stop25h 50mAmerican Airlines
Tue 12/3010:25 pmSCL - DTW
1 stop27h 32mAmerican Airlines
Deal found 12/11$1,110
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amDTW - SCL
2 stops24h 50mUnited Airlines
Wed 12/3110:45 pmSCL - DTW
1 stop26h 58mUnited Airlines
Deal found 12/10$1,153

Find flight deals from Detroit to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$629
(Mytrip)

One-way from

$282
(Kiwi.com)

Popular in

July

Cheapest in

October

Average price

$1,284
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Santiago Arturo Merino Benitez flights.
Search Deals
From Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($103 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santiago that are best for you.

Fly from

Detroit

Fly to

Santiago

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 4/12

12:22 pm-11:15 am

3 stops22h 53m

Santiago Arturo Merino Benitez

Mon 4/13

12:55 am-11:41 pm

3 stops22h 46m

$629

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 3/4

9:10 pm-3:20 pm

2 stops40h 10m

Santiago Arturo Merino Benitez

Wed 3/11

11:25 pm-10:03 pm

1 stop23h 38m

$642

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 1/29

6:35 am-5:30 am

2 stops20h 55m

Santiago Arturo Merino Benitez

Sat 2/14

4:25 pm-9:11 am

2 stops18h 46m

$775

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 1/29

12:15 pm-9:00 am

1 stop18h 45m

Santiago Arturo Merino Benitez

Tue 2/10

10:30 pm-4:32 pm

1 stop20h 02m

$864

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 3/24

5:05 am-5:30 am

2 stops23h 25m

Santiago Arturo Merino Benitez

Sat 4/4

7:10 am-11:41 pm

2 stops17h 31m

$891

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 1/29

1:23 pm-8:15 am

1 stop16h 52m

Santiago Arturo Merino Benitez

Sat 2/14

10:00 pm-12:06 pm

1 stop16h 06m

$904

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 1/15

11:20 am-8:15 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Sat 1/31

10:30 pm-8:44 pm

1 stop24h 14m

$904

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 1/15

7:00 am-8:15 am

1 stop23h 15m

Santiago Arturo Merino Benitez

Sat 1/24

11:55 pm-11:30 am

1 stop13h 35m

$904

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 1/18

2:47 pm-2:40 pm

2 stops45h 53m

$282

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 1/19

4:21 pm-6:40 am

2 stops36h 19m

$293

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 14 results
1
2

Compare providers for flights from Detroit to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Santiago in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Detroit Metropolitan Wayne County Airport-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Santiago

What is the cheapest time of day to fly from DTW to SCL?

Find hourly flight availability from Detroit to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 18% on flights from Detroit Metropolitan Wayne County Airport to Santiago by exploring options for tickets in the evening.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 12, 2025.
Peruse reviews from past customers who have flown with Delta, LATAM Airlines, and American Airlines from Detroit Metropolitan Wayne County Airport to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,889 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Santiago?

    Departing from Detroit Metropolitan Wayne County Airport to Santiago will take you 18h 45m. Airlines will cover a distance of 5281 mi.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Santiago round-trip?

    According to our current data, LATAM Airlines ($733), American Airlines ($822), and Delta ($873) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Santiago. Users have found that LATAM Airlines is 37% cheaper than the other options available to this destination.

  • Can I find deals for flights from Detroit to Santiago that include hotel bookings?

    Yes. In addition to deals on Detroit to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Santiago.

  • Can I find deals for business class flights from Detroit to Santiago?

    Yes. Cheapflights offers flight deals from Detroit to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Detroit to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Detroit to Easter Island flights

Top 3 airlines flying from Detroit to Santiago

Discover the top 3 airlines that operate flights from Detroit to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$733Average$1,418FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$822Average$1,108FlexibilityNo cancel feeOn-time71%
DeltaCheapest$873Average$1,383FlexibilityNo cancel feeOn-timeN/A

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