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$226+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SCL
ago 3 — ago 101
dom 8/3
dom 8/10
1 adult, Economy
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Cheap flight deals from Detroit to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julho 29, 2025.

Round-trip from

$574
(Kiwi.com)

One-way from

$226
(Avianca Connect)

Popular in

June

Cheapest in

October

Average price

$1,227
From Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
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One-way flight from Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 7% potential increase in price ($88 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Detroit to Santiago

Cheapest flights from Detroit to Santiago
Explore the most affordable flight options available from Detroit to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julho 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 10/206:05 amDTW - SCL
2 stops31h 20mMultiple Airlines
sex 11/1410:50 amSCL - DTW
1 stop29h 19mMultiple Airlines
Deal found 7/27$574
This LATAM Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 10/221:31 pmDTW - SCL
1 stop15h 29mLATAM Airlines
qua 11/1211:25 pmSCL - DTW
1 stop23h 24mLATAM Airlines
Deal found 7/29$855
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/811:05 amDTW - SCL
2 stops19h 45mUnited Airlines
sex 12/1910:45 pmSCL - DTW
1 stop19h 04mUnited Airlines
Deal found 7/28$884

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julho 29, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santiago that are best for you.

Fly from

Detroit

Fly to

Santiago

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

seg 10/20

6:05 am-2:25 pm

2 stops31h 20m

Santiago Arturo Merino Benitez

sex 11/14

10:50 am-2:09 pm

1 stop29h 19m

$574

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

qua 10/22

1:31 pm-6:00 am

1 stop15h 29m

Santiago Arturo Merino Benitez

qua 11/12

11:25 pm-8:49 pm

1 stop23h 24m

$855

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

seg 12/8

11:05 am-8:50 am

2 stops19h 45m

Santiago Arturo Merino Benitez

sex 12/19

10:45 pm-3:49 pm

1 stop19h 04m

$884

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

qua 11/12

7:00 am-5:10 am

2 stops20h 10m

$226

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

qui 11/13

10:30 am-6:35 am

3 stops18h 05m

$863

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Best time to book a flight from Detroit to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Santiago

What is the cheapest time of day to fly from DTW to SCL?

Find hourly flight availability from Detroit to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julho 29, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 19% on flights from Detroit Metropolitan Wayne County Airport to Santiago by exploring options for tickets in the evening.

How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated julho 29, 2025.
Peruse reviews from past customers who have flown with LATAM Airlines and United Airlines from Detroit Metropolitan Wayne County Airport to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,821 reviews

Comfort

7.4

Boarding

7.6

Crew

8.1

Entertainment

7.0

Food

6.7

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
LATAM Airlines
7.5
Good
1,821 reviews
LATAM Airlines
7.5
Good
1,821 reviews

Comfort

7.4

Boarding

7.6

Crew

8.1

Entertainment

7.0

Food

6.7

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
United Airlines
7.4
Good
8,899 reviews
LATAM Airlines
7.5
Good
1,821 reviews

Comfort

7.4

Boarding

7.6

Crew

8.1

Entertainment

7.0

Food

6.7

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

Related info for your journey

Find useful and relevant information for your journey from Detroit to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Santiago round-trip?

    According to our current data, LATAM Airlines ($855), and United Airlines ($884) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Santiago. Users have found that LATAM Airlines is 23% cheaper than the other options available to this destination.

  • Can I find deals for flights from Detroit to Santiago that include hotel bookings?

    Yes. In addition to deals on Detroit to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Santiago.

  • Can I find deals for business class flights from Detroit to Santiago?

    Yes. Cheapflights offers flight deals from Detroit to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Santiago (average of $752). Flying from Detroit Metropolitan Wayne County Airport to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Detroit to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Detroit to Easter Island flights

Top 4 airlines flying from Detroit to Santiago

Discover the top 4 airlines that operate flights from Detroit to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julho 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air CanadaCheapest$684Average$946FlexibilityNo cancel feeOn-time67%
LATAM AirlinesCheapest$733Average$1,172FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$822Average$1,079FlexibilityNo cancel feeOn-time71%
DeltaCheapest$873Average$1,264FlexibilityNo cancel feeOn-timeN/A

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