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$260+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SCL
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Detroit to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$722
(Avianca Connect)

One-way from

$260
(Mytrip)

Popular in

June

Cheapest in

October

Average price

$1,512
From Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
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One-way flight from Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 9% potential increase in price ($113 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($38 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Detroit to Santiago

Cheapest flights from Detroit to Santiago
Explore the most affordable flight options available from Detroit to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Avianca Connect deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/45:40 amDTW - SCL
2 stops21h 45mMultiple Airlines
Mon 11/1012:45 amSCL - DTW
2 stops20h 49mMultiple Airlines
Deal found 6/10$722
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2210:31 amDTW - SCL
2 stops20h 34mAmerican Airlines
Wed 11/1210:15 pmSCL - DTW
1 stop20h 33mAmerican Airlines
Deal found 6/12$798
This Cheapflightsfares deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/224:10 pmDTW - SCL
2 stops20h 45mLATAM Airlines
Wed 11/1210:50 pmSCL - DTW
1 stop14h 20mLATAM Airlines
Deal found 6/10$800
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/218:25 amDTW - SCL
1 stop20h 35mDelta
Tue 11/1111:15 pmSCL - DTW
1 stop15h 19mDelta
Deal found 6/10$804
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/310:59 amDTW - SCL
1 stop19h 51mUnited Airlines
Tue 11/1110:45 pmSCL - DTW
1 stop19h 14mUnited Airlines
Deal found 6/10$824
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/76:00 amDTW - SCL
2 stops23h 04mCopa Airlines
Sun 8/1712:12 amSCL - DTW
2 stops21h 53mCopa Airlines
Deal found 6/10$959
This Air Canada deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/58:55 pmDTW - SCL
1 stop13h 15mAir Canada
Tue 11/118:50 pmSCL - DTW
1 stop15h 01mAir Canada
Deal found 6/10$963
This Iberia deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/218:53 pmDTW - SCL
2 stops34h 27mIberia
Mon 11/109:10 pmSCL - DTW
2 stops51h 39mIberia
Deal found 6/11$2,315

Cheapflights Fare Finder

Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santiago that are best for you.

Fly from

Detroit

Fly to

Santiago

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 11/4

5:40 am-5:25 am

2 stops21h 45m

Santiago Arturo Merino Benitez

Mon 11/10

12:45 am-7:34 pm

2 stops20h 49m

$722

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 10/22

10:31 am-8:05 am

2 stops20h 34m

Santiago Arturo Merino Benitez

Wed 11/12

10:15 pm-4:48 pm

1 stop20h 33m

$798

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 10/22

4:10 pm-1:55 pm

2 stops20h 45m

Santiago Arturo Merino Benitez

Wed 11/12

10:50 pm-11:10 am

1 stop14h 20m

$800

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 10/21

8:25 am-6:00 am

1 stop20h 35m

Santiago Arturo Merino Benitez

Tue 11/11

11:15 pm-12:34 pm

1 stop15h 19m

$804

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 11/3

10:59 am-8:50 am

1 stop19h 51m

Santiago Arturo Merino Benitez

Tue 11/11

10:45 pm-3:59 pm

1 stop19h 14m

$824

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 8/7

6:00 am-5:04 am

2 stops23h 04m

Santiago Arturo Merino Benitez

Sun 8/17

12:12 am-10:05 pm

2 stops21h 53m

$959

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 11/5

8:55 pm-12:10 pm

1 stop13h 15m

Santiago Arturo Merino Benitez

Tue 11/11

8:50 pm-9:51 am

1 stop15h 01m

$963

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 10/21

8:53 pm-8:20 am

2 stops34h 27m

Santiago Arturo Merino Benitez

Mon 11/10

9:10 pm-10:49 pm

2 stops51h 39m

$2,315

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 11/5

3:49 pm-3:35 am

2 stops33h 46m

$260

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 11/5

8:25 am-6:55 am

1 stop20h 30m

$539

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Showing 1-10 of 12 results
1
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Best time to book a flight from Detroit to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Santiago

What is the cheapest time of day to fly from DTW to SCL?

Find hourly flight availability from Detroit to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 19% on flights from Detroit Metropolitan Wayne County Airport to Santiago by exploring options for tickets in the evening.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,785 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Santiago round-trip?

    According to our current data, American Airlines ($798), LATAM Airlines ($800), and Delta ($804) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Santiago. Users have found that American Airlines is 29% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Detroit Metropolitan Wayne County Airport to Santiago one-way?

    The cheapest airlines for a one-way flight from Detroit Metropolitan Wayne County Airport to Santiago are LATAM Airlines ($539), American Airlines ($543), and Delta ($558).

  • Can I find deals for flights from Detroit to Santiago that include hotel bookings?

    Yes. In addition to deals on Detroit to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Santiago.

  • Can I find deals for business class flights from Detroit to Santiago?

    Yes. Cheapflights offers flight deals from Detroit to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Santiago (average of $752). Flying from Detroit Metropolitan Wayne County Airport to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Detroit to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Detroit to Easter Island flights

Top 4 airlines flying from Detroit to Santiago

Discover the top 4 airlines that operate flights from Detroit to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air CanadaCheapest$789Average$946FlexibilityNo cancel feeOn-time67%
American AirlinesCheapest$822Average$1,126FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$832Average$1,272FlexibilityNo cancel feeOn-time81%
DeltaCheapest$873Average$1,251FlexibilityNo cancel feeOn-timeN/A

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