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$273+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SCL
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Detroit to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$640
(Kiwi.com)

One-way from

$273
(Mytrip)

Popular in

December

Cheapest in

October

Average price

$969
From Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
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One-way flight from Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 1% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($36 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Detroit to Santiago

Cheapest flights from Detroit to Santiago
Explore the most affordable flight options available from Detroit to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/206:17 amDTW - SCL
2 stops31h 28mMultiple Airlines
mié. 11/1211:25 pmSCL - DTW
1 stop16h 44mMultiple Airlines
Deal found 9/10$640
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/246:17 amDTW - SCL
3 stops29h 03mMultiple Airlines
mié. 11/1211:25 pmSCL - DTW
1 stop16h 44mMultiple Airlines
Deal found 9/10$641
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/206:17 amDTW - SCL
3 stops29h 03mMultiple Airlines
mar. 11/1111:25 pmSCL - DTW
1 stop16h 44mMultiple Airlines
Deal found 9/11$643
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/206:17 amDTW - SCL
2 stops31h 28mMultiple Airlines
lun. 11/1010:50 amSCL - DTW
1 stop29h 19mMultiple Airlines
Deal found 9/10$644
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/246:17 amDTW - SCL
3 stops29h 03mMultiple Airlines
lun. 11/1010:50 amSCL - DTW
1 stop29h 19mMultiple Airlines
Deal found 9/10$645
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/246:17 amDTW - SCL
3 stops29h 03mMultiple Airlines
mar. 11/1111:25 pmSCL - DTW
1 stop16h 44mMultiple Airlines
Deal found 9/10$654
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/206:17 amDTW - SCL
2 stops31h 28mMultiple Airlines
jue. 11/1311:25 pmSCL - DTW
1 stop16h 44mMultiple Airlines
Deal found 9/11$655

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santiago that are best for you.

Fly from

Detroit

Fly to

Santiago

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mié. 10/22

6:43 am-5:15 am

2 stops21h 32m

Santiago Arturo Merino Benitez

mié. 11/12

4:25 pm-2:09 pm

2 stops23h 44m

$670

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

jue. 10/23

6:17 am-3:35 am

2 stops20h 18m

Santiago Arturo Merino Benitez

lun. 11/10

10:50 am-2:09 pm

1 stop29h 19m

$711

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mié. 10/15

9:30 am-5:15 am

2 stops18h 45m

Santiago Arturo Merino Benitez

jue. 10/16

12:55 am-8:00 pm

2 stops20h 05m

$758

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mar. 9/23

6:41 am-5:15 am

2 stops21h 34m

Santiago Arturo Merino Benitez

jue. 9/25

12:55 am-10:40 pm

2 stops22h 45m

$808

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mié. 9/24

7:35 pm-7:00 am

1 stop34h 25m

Santiago Arturo Merino Benitez

sáb. 9/27

11:00 am-8:14 pm

1 stop34h 14m

$834

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mié. 10/22

12:38 pm-6:45 am

2 stops17h 07m

Santiago Arturo Merino Benitez

lun. 11/10

12:55 am-6:43 pm

2 stops19h 48m

$914

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

jue. 10/23

1:31 pm-6:50 am

1 stop16h 19m

Santiago Arturo Merino Benitez

lun. 11/10

11:10 pm-12:57 pm

1 stop15h 47m

$914

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mar. 10/21

1:31 pm-6:50 am

1 stop16h 19m

Santiago Arturo Merino Benitez

lun. 11/10

11:25 pm-11:09 am

1 stop13h 44m

$914

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mié. 10/22

7:45 pm-2:25 pm

2 stops17h 40m

Santiago Arturo Merino Benitez

mar. 11/11

12:55 am-6:43 pm

2 stops19h 48m

$914

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

lun. 10/27

6:17 am-12:15 pm

3 stops28h 58m

$273

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Detroit to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Santiago

What is the cheapest time of day to fly from DTW to SCL?

Find hourly flight availability from Detroit to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 19% on flights from Detroit Metropolitan Wayne County Airport to Santiago by exploring options for tickets in the evening.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated septiembre 11, 2025.
Peruse reviews from past customers who have flown with Delta, LATAM Airlines, and American Airlines from Detroit Metropolitan Wayne County Airport to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air Canada
7.1
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Santiago round-trip?

    According to our current data, Air Canada ($684), LATAM Airlines ($733), and Delta ($768) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Santiago. Users have found that Air Canada is 39% cheaper than the other options available to this destination.

  • Can I find deals for flights from Detroit to Santiago that include hotel bookings?

    Yes. In addition to deals on Detroit to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Santiago.

  • Can I find deals for business class flights from Detroit to Santiago?

    Yes. Cheapflights offers flight deals from Detroit to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Santiago (average of $752). Flying from Detroit Metropolitan Wayne County Airport to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Detroit to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Detroit to Easter Island flights

Top 4 airlines flying from Detroit to Santiago

Discover the top 4 airlines that operate flights from Detroit to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air CanadaCheapest$684Average$946FlexibilityNo cancel feeOn-time67%
LATAM AirlinesCheapest$733Average$1,272FlexibilityNo cancel feeOn-time81%
DeltaCheapest$768Average$1,267FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$822Average$1,047FlexibilityNo cancel feeOn-time71%

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