HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$376+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SCL
fev 25 — mar 41
qua 2/25
qua 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Detroit to Santiago

Cheapest flights from Detroit to Santiago
Explore the most affordable flight options available from Detroit to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on janeiro 26, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 2/19:10 pm
DTW
-
SCL
2 stops30h 20m
Multiple Airlines
qui 2/510:35 am
SCL
-
DTW
1 stop13h 37m
Multiple Airlines
Deal found 1/25$703
This Mytrip deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 3/410:59 pm
DTW
-
SCL
2 stops26h 36m
Multiple Airlines
qua 3/119:05 pm
SCL
-
DTW
2 stops23h 41m
Multiple Airlines
Deal found 1/26$723
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 3/124:50 pm
DTW
-
SCL
3 stops42h 10m
Multiple Airlines
qui 3/1910:35 am
SCL
-
DTW
1 stop14h 24m
Multiple Airlines
Deal found 1/26$743
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 1/276:35 am
DTW
-
SCL
2 stops20h 55m
Multiple Airlines
dom 3/17:15 am
SCL
-
DTW
2 stops28h 31m
Multiple Airlines
Deal found 1/25$776
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 3/46:00 am
DTW
-
SCL
1 stop24h 05m
American Airlines
qua 3/1110:15 pm
SCL
-
DTW
1 stop24h 04m
American Airlines
Deal found 1/26$858

Find flight deals from Detroit to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated janeiro 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$746
(Kiwi.com)

One-way from

$376
(Kiwi.com)

Popular in

July

Cheapest in

October

Average price

$1,113
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Santiago Arturo Merino Benitez flights.
Search Deals
From Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($78 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated janeiro 26, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santiago that are best for you.

Fly from

Detroit

Fly to

Santiago

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

qua 3/4

10:59 pm-3:35 am

2 stops26h 36m

Santiago Arturo Merino Benitez

qua 3/11

4:25 pm-7:46 pm

3 stops28h 21m

$730

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

qui 3/12

12:22 pm-10:15 pm

3 stops32h 53m

Santiago Arturo Merino Benitez

qui 3/19

9:05 pm-11:59 pm

2 stops27h 54m

$767

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

qui 3/12

10:55 am-7:50 am

1 stop19h 55m

Santiago Arturo Merino Benitez

qui 3/19

9:45 pm-4:01 pm

1 stop19h 16m

$858

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

qua 3/4

6:00 am-8:05 am

1 stop24h 05m

Santiago Arturo Merino Benitez

qua 3/11

10:15 pm-9:19 pm

1 stop24h 04m

$858

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

qua 4/1

6:00 pm-7:50 am

1 stop12h 50m

Santiago Arturo Merino Benitez

qua 4/22

8:30 pm-5:27 pm

1 stop20h 57m

$858

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

ter 5/5

5:57 pm-6:50 am

1 stop12h 53m

Santiago Arturo Merino Benitez

ter 5/12

8:30 pm-5:27 pm

1 stop20h 57m

$858

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

sáb 1/31

3:16 pm-4:55 am

2 stops35h 39m

$376

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

dom 2/22

7:28 am-8:50 am

2 stops47h 22m

$445

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

dom 2/22

10:35 am-11:02 am

3 stops22h 27m

$1,622

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Compare providers for flights from Detroit to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Santiago in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Santiago

How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated janeiro 26, 2026.
Peruse reviews from past customers who have flown with Delta and LATAM Airlines from Detroit Metropolitan Wayne County Airport to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,112 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,112 reviews
Delta
7.9
Good
8,112 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,912 reviews
Delta
7.9
Good
8,112 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Santiago?

    Departing from Detroit Metropolitan Wayne County Airport to Santiago will take you 12h 50m. Airlines will cover a distance of 5281 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Santiago round-trip?

    According to our current data, Delta ($563), and LATAM Airlines ($733) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Santiago. Users have found that Delta is 53% cheaper than the other options available to this destination.

  • Can I find deals for flights from Detroit to Santiago that include hotel bookings?

    Yes. In addition to deals on Detroit to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Santiago.

  • Can I find deals for business class flights from Detroit to Santiago?

    Yes. Cheapflights offers flight deals from Detroit to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Detroit to Easter Island flights

Top 2 airlines flying from Detroit to Santiago

Discover the top 2 airlines that operate flights from Detroit to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated janeiro 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$563Average$1,188FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$733Average$1,368FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.