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$126+ Cheap flights from Cusco (CUZ) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
CUZ — SCL
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheapflights Tip: The best prices from Cusco Velazco Astete to Santiago Arturo Merino Benitez are usually found in December or October, booked 16 days in advance, depart on a Monday or Thursday and return on a Saturday

Cheap flight deals from Cuzco to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Cuzco (CUZ) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$289
(Booking.com)

One-way from

$126
(Mytrip)

Popular in

January

Cheapest in

December

Average price

$272

Good one-way deal

$234 or less
Provider with most accurate pricing for Cusco Velazco Astete-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cusco Velazco Astete-Santiago Arturo Merino Benitez flights.
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From Cusco Velazco Astete to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Cusco Velazco Astete to Santiago Arturo Merino Benitez
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals
Price to beat on a one-way flight from Cusco Velazco Astete to Santiago Arturo Merino Benitez.
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Find flight deals from Cuzco to Santiago

Cheapest flights from Cuzco to Santiago
Explore the most affordable flight options available from Cuzco to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This Booking.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1110:40 pmCUZ - SCL
1 stop16h 45mMultiple Airlines
Sun 5/1810:10 pmSCL - CUZ
1 stop22h 45mMultiple Airlines
Deal found 4/27$289
This CheapOair deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:40 pmCUZ - SCL
1 stop16h 05mSky Airline
Sun 5/1810:10 pmSCL - CUZ
2 stops12h 00mSky Airline
Deal found 4/27$312
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1111:55 pmCUZ - SCL
1 stop12h 10mLATAM Airlines
Sun 5/182:40 pmSCL - CUZ
Nonstop3h 35mLATAM Airlines
Deal found 4/27$375
This Avianca deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/112:15 pmCUZ - SCL
1 stop24h 10mAvianca
Sat 6/216:10 amSCL - CUZ
1 stop29h 50mAvianca
Deal found 4/29$1,034

Cheapflights Fare Finder

Customize your flight search to find flights from Cuzco to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Cusco to Santiago that are best for you.

Fly from

Cuzco

Fly to

Santiago

Route

Depart

Return

Price

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Sun 5/11

10:40 pm-4:25 pm

1 stop16h 45m

Santiago Arturo Merino Benitez

Sun 5/18

10:10 pm-7:55 pm

1 stop22h 45m

$289

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Sun 5/11

8:40 pm-1:45 pm

1 stop16h 05m

Santiago Arturo Merino Benitez

Sun 5/18

10:10 pm-9:10 am

2 stops12h 00m

$312

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Sun 5/11

11:55 pm-1:05 pm

1 stop12h 10m

Santiago Arturo Merino Benitez

Sun 5/18

2:40 pm-5:15 pm

Nonstop3h 35m

$375

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Sun 6/1

12:15 pm-1:25 pm

1 stop24h 10m

Santiago Arturo Merino Benitez

Sat 6/21

6:10 am-11:00 am

1 stop29h 50m

$1,034

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Tue 6/10

7:25 am-9:25 am

2 stops25h 00m

$126

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Sun 5/11

4:17 pm-4:01 am

1 stop10h 44m

$141

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Fri 6/6

9:30 am-1:50 pm

Nonstop3h 20m

$156

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Compare providers for flights from Cuzco to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Cuzco to Santiago in April.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Cusco-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Cusco-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Cusco-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cusco-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cusco-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cuzco to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cuzco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cusco to Santiago

How far ahead should I book a flight from Cusco to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Cuzco to Santiago. Price data was last updated on April 25, 2025.

To ensure you get the cheapest price possible for a flight from Cusco to Santiago, you should look to book at least 16 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cusco to Santiago?

Currently, April is the cheapest month in which you can book a flight from Cusco to Santiago (average of $752). Flying from Cusco to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CUZ to SCL?

Find hourly flight availability from Cuzco to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

When flying from Cusco to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 24% versus a flight at noon.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 29, 2025.
LATAM Airlines
7.5
Good
1,767 reviews

Entertainment

7.0

Boarding

7.6

Comfort

7.4

Food

6.7

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
LATAM Airlines
7.5
Good
1,767 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Entertainment

7.0

Boarding

7.6

Comfort

7.4

Food

6.7

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Avianca
6.7
Okay
2,317 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Entertainment

7.0

Boarding

7.6

Comfort

7.4

Food

6.7

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
JetSMART
6.6
Okay
186 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Entertainment

7.0

Boarding

7.6

Comfort

7.4

Food

6.7

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Related info for your journey

Find useful and relevant information for your journey from Cuzco to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Cusco to Santiago round-trip?

    Flying on Sky Airline is currently your cheapest option to Santiago, with prices starting at $312. Additional round-trip tickets that might be worth considering are offered by LATAM Airlines and Avianca, with the lowest prices starting at $375 and $1,034, respectively.

  • What are the cheapest airlines to fly from Cusco to Santiago one-way?

    To fly one-way, consider booking your trip with Sky Airline, which is currently one of the cheapest options available, starting at $126. JetSMART flights start at $141 while deals on LATAM Airlines start at $156 one-way.

  • What are the cheapest flights from Cusco to Santiago?

    While on average a flight from Cusco to Santiago is generally $269, our data shows the cheapest flight currently is $160. When looking at the most popular route, (Cusco Velazco Astete - Santiago Arturo Merino Benitez), you can expect to pay $273 for that flight.

  • Can I find deals for flights from Cuzco to Santiago that include hotel bookings?

    Yes. In addition to deals on Cuzco to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cuzco to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cuzco to Santiago.

  • Can I find deals for business class flights from Cuzco to Santiago?

    Yes. Cheapflights offers flight deals from Cuzco to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cusco to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Cusco to Santiago (average of $752). Flying from Cusco to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Cuzco to Santiago

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Top airline flying from Cuzco to Santiago

Discover the top airline that operate flights from Cuzco to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$275Average$414FlexibilityNo cancel feeOn-time81%

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