What is the most punctual flight time for Cusco to Santiago flights?

Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Friday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Cusco to Santiago flights?

Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 4% of flights being delayed.

How often are flights from Cusco to Santiago delayed?

About 4% of weekly flights between Cusco and Santiago have experienced delays in the past year, with the average delay time being 175 minutes.

How long is the flight from Cusco to Santiago?

A quick flight from Cusco to Santiago can take about 27h 10m. Sky Airline provides one of the quickest options available for as low as $279. The distance from Cusco to Santiago is about 1373 mi.

What is the cheapest airline to fly from Cusco to Santiago round-trip?

Flying on LATAM Airlines is currently your cheapest option to Santiago, with prices starting at $275. Users have found that LATAM Airlines is 12% cheaper than the other options available to this destination.

What are the cheapest airlines to fly from Cusco to Santiago one-way?

To fly one-way, consider booking your trip with JetSMART, which is currently one of the cheapest options available, starting at $100. Sky Airline flights start at $108 while deals on LATAM Airlines start at $145 one-way.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

What are the cheapest flights from Cusco to Santiago?

While on average a flight from Cusco to Santiago is generally $261, our data shows the cheapest flight currently is $105. When looking at the most popular route, (Cusco Velazco Astete - Santiago Arturo Merino Benitez), you can expect to pay $274 for that flight.

Most accurate provider : When it comes to deals on Cusco-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Cusco-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Cusco-Santiago flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Cusco-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cusco-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Cuzco to Santiago that include hotel bookings?

Yes. In addition to deals on Cuzco to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Cuzco to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cuzco to Santiago.

Can I find deals for business class flights from Cuzco to Santiago?

Yes. Cheapflights offers flight deals from Cuzco to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$119+ Flights from Cusco to Santiago

Q: How much does it cost to fly round-trip from Cusco to Santiago?

Airfare is typical for this route at the moment. Cusco to Santiago flights typically cost between $237 and $384 in April. The cheapest round-trip price found within the last 3 days was $251 on Multiple Airlines (Apr 9-Apr 12).

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Cheap flight deals from Cuzco to Santiago

Cheapest flights from Cuzco to Santiago
Explore the most affordable flight options available from Cuzco to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.

Fri 12/264:45 pmCUZ - SCL

2 stops17h 30mSky Airline

Fri 1/212:35 pmSCL - CUZ

1 stop11h 20mSky Airline

Deal found 12/5

$642

Best flights from Cuzco to Santiago
Discover carefully curated flight deals from Cuzco to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 7, 2025.

Thu 4/94:42 pmCUZ - SCL

1 stop10h 19mMultiple Airlines

Sun 4/128:15 pmSCL - CUZ

1 stop12h 05mMultiple Airlines

Deal found 12/5

$251

Thu 4/97:05 amCUZ - SCL

2 stops27h 10mSky Airline

Sun 4/128:15 pmSCL - CUZ

1 stop21h 00mSky Airline

Deal found 12/5

$279

Wed 1/219:45 pmCUZ - SCL

1 stop14h 55mSky Airline

Wed 1/2811:05 pmSCL - CUZ

1 stop9h 20mSky Airline

Deal found 12/7

$282

Last-minute flights from Cuzco to Santiago
Discover last-minute flight deals from Cuzco to Santiago. Data last updated December 7, 2025 and is based on user searches.

Fri 12/264:45 pmCUZ - SCL

2 stops17h 30mSky Airline

Fri 1/212:35 pmSCL - CUZ

1 stop11h 20mSky Airline

Deal found 12/5

$642

Mon 1/56:30 pmCUZ - SCL

2 stops15h 45mSky Airline

Sun 1/181:35 amSCL - CUZ

2 stops21h 40mSky Airline

Deal found 12/5

$662

Mon 1/197:05 amCUZ - SCL

2 stops27h 10mSky Airline

Mon 1/269:05 pmSCL - CUZ

1 stop12h 15mSky Airline

Deal found 12/5

$286

Mon 1/196:35 pmCUZ - SCL

1 stop10h 05mMultiple Airlines

Mon 1/263:45 pmSCL - CUZ

Nonstop3h 30mMultiple Airlines

Deal found 12/5

$415

Wed 1/219:45 pmCUZ - SCL

1 stop14h 55mSky Airline

Wed 1/2811:05 pmSCL - CUZ

1 stop9h 20mSky Airline

Deal found 12/7

$282

Wed 1/219:45 pmCUZ - SCL

1 stop14h 55mMultiple Airlines

Wed 1/283:45 pmSCL - CUZ

Nonstop3h 30mMultiple Airlines

Deal found 12/7

$310

Wed 1/219:30 amCUZ - SCL

Nonstop3h 15mLATAM Airlines

Wed 1/283:45 pmSCL - CUZ

Nonstop3h 30mLATAM Airlines

Deal found 12/7

$426

One-way flights from Cuzco to Santiago
Search for one-way flight options from Cuzco to Santiago. Find affordable one-way fares based on user searches. Data last updated December 7, 2025.

Thu 4/94:42 pmCUZ - SCL

1 stop10h 19mJetSMART

Deal found 12/5

$119

Fri 5/295:17 pmCUZ - SCL

1 stop9h 44mJetSMART

Deal found 12/6

$121

Thu 4/911:10 amCUZ - SCL

2 stops23h 05mSky Airline

Deal found 12/5

$137

Fri 5/112:05 pmCUZ - SCL

2 stops22h 10mSky Airline

Deal found 12/7

$138

Wed 3/117:05 amCUZ - SCL

2 stops27h 10mSky Airline

Deal found 12/5

$141

Sun 4/55:17 pmCUZ - SCL

1 stop9h 44mJetSMART

Deal found 12/5

$144

Thu 4/99:30 amCUZ - SCL

Nonstop3h 20mLATAM Airlines

Deal found 12/7

$145

Thu 1/159:45 pmCUZ - SCL

1 stop14h 55mSky Airline

Deal found 12/6

$146

Sun 4/57:05 amCUZ - SCL

2 stops27h 10mSky Airline

Deal found 12/5

$155

Thu 1/157:12 amCUZ - SCL

1 stop11h 32mJetSMART

Deal found 12/7

$158

Find flight deals from Cuzco to Santiago

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$251 (Trip.com)
One-way from	$119 (FlightHub)
Popular in	June
Cheapest in	October
Average price	$276
Good one-way deal	$188 or less

Provider with most accurate pricing for Cusco Velazco Astete-Santiago Arturo Merino Benitez flight deals.

Search Deals

Provider most trusted by Cheapflights users for Cusco Velazco Astete-Santiago Arturo Merino Benitez flights.

Search Deals

From Cusco Velazco Astete to Santiago Arturo Merino Benitez

Search Deals

One-way flight from Cusco Velazco Astete to Santiago Arturo Merino Benitez

Search Deals

Highest demand for flights based on searches. 14% potential increase in price ($52 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a one-way flight from Cusco Velazco Astete to Santiago Arturo Merino Benitez.

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

4:42 pm-4:01 am

1 stop10h 19m

Santiago Arturo Merino Benitez

Sun 4/12

8:15 pm-7:20 am

1 stop12h 05m

$251

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

7:05 am-11:15 am

2 stops27h 10m

Santiago Arturo Merino Benitez

Sun 4/12

8:15 pm-4:15 pm

1 stop21h 00m

$279

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Wed 1/21

9:45 pm-2:40 pm

1 stop14h 55m

Santiago Arturo Merino Benitez

Wed 1/28

11:05 pm-6:25 am

1 stop9h 20m

$282

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

4:42 pm-4:01 am

1 stop10h 19m

$119

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Fri 5/29

5:17 pm-4:01 am

1 stop9h 44m

$121

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

11:10 am-11:15 am

2 stops23h 05m

$137

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Sat 5/30

9:20 pm-1:45 pm

1 stop15h 25m

$137

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Fri 5/1

12:05 pm-11:15 am

2 stops22h 10m

$138

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Wed 3/11

7:05 am-12:15 pm

2 stops27h 10m

$141

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Sun 4/5

5:17 pm-4:01 am

1 stop9h 44m

$144

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Compare providers for flights from Cuzco to Santiago

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Cuzco to Santiago in December.

Provider	Price Accuracy	Trust Score*
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Cusco-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Cusco-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Cusco-Santiago flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Cusco-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cusco-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cuzco to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cuzco with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cusco to Santiago

Prices

Delays

How far ahead should I book a flight from Cusco to Santiago?

To ensure you get the cheapest price possible for a flight from Cusco to Santiago, you should look to book at least 51 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cusco to Santiago?

Currently, October is the cheapest month in which you can book a flight from Cusco to Santiago (average of $113). Flying from Cusco to Santiago in July is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CUZ to SCL?

When flying from Cusco to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Cusco to Santiago?

Reviews of airlines servicing Santiago

Read through reviews of airlines operating flights from Cusco to Santiago, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

LATAM Airlines

7.5

Good

1,889 reviews

Reviews

1 / 20

8.0

Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

LATAM Airlines

7.5

Good

1,889 reviews

LATAM Airlines

7.5

Good

1,889 reviews

Reviews

1 / 20

8.0

Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

Related info for your journey

How long is the flight from Cusco to Santiago?
A quick flight from Cusco to Santiago can take about 27h 10m. Sky Airline provides one of the quickest options available for as low as $279. The distance from Cusco to Santiago is about 1373 mi.
What is the cheapest airline to fly from Cusco to Santiago round-trip?
Flying on LATAM Airlines is currently your cheapest option to Santiago, with prices starting at $275. Users have found that LATAM Airlines is 12% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from Cusco to Santiago one-way?
To fly one-way, consider booking your trip with JetSMART, which is currently one of the cheapest options available, starting at $100. Sky Airline flights start at $108 while deals on LATAM Airlines start at $145 one-way.
What are the cheapest flights from Cusco to Santiago?
While on average a flight from Cusco to Santiago is generally $261, our data shows the cheapest flight currently is $105. When looking at the most popular route, (Cusco Velazco Astete - Santiago Arturo Merino Benitez), you can expect to pay $274 for that flight.
Can I find deals for flights from Cuzco to Santiago that include hotel bookings?
Yes. In addition to deals on Cuzco to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Cuzco to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cuzco to Santiago.
Can I find deals for business class flights from Cuzco to Santiago?
Yes. Cheapflights offers flight deals from Cuzco to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Cusco to Santiago?
Currently, October is the cheapest month in which you can book a flight from Cusco to Santiago (average of $113). Flying from Cusco to Santiago in July is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Cuzco to Santiago

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Lima to Punta Arenas flights

Arequipa to Santiago flights

Other flights to Santiago

Top airline flying from Cuzco to Santiago

Airline	Cheapest	Average	Flexibility	On-time
LATAM Airlines	Cheapest$275	Average$414	FlexibilityNo cancel fee	On-time81%

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$119+ Cheap flights from Cusco (CUZ) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/9. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Cuzco to Santiago with Cheapflights

1. Tell us where you want to go

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Cheap flight deals from Cuzco to Santiago

Cheapest flights from Cuzco to SantiagoExplore the most affordable flight options available from Cuzco to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.

Explore the most affordable flight options available from Cuzco to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.

Find flight deals from Cuzco to Santiago

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Cusco to Santiago that are best for you.

Compare providers for flights from Cuzco to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Cuzco to Santiago in December.

Best time to book a flight from Cuzco to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cuzco with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Cusco to Santiago

How far ahead should I book a flight from Cusco to Santiago?

What is the cheapest month to book a flight from Cusco to Santiago?

What is the cheapest time of day to fly from CUZ to SCL?

How much does it cost to fly round-trip from Cusco to Santiago?

How often are flights from Cusco to Santiago delayed?

What is the most punctual flight time for Cusco to Santiago flights?

What day of the week experiences the fewest flight delays on this route?

Which airline has the best punctuality record on Cusco to Santiago flights?

Reviews of airlines servicing Santiago

Read through reviews of airlines operating flights from Cusco to Santiago, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Cuzco to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Cusco to Santiago?

What is the cheapest airline to fly from Cusco to Santiago round-trip?

What are the cheapest airlines to fly from Cusco to Santiago one-way?

What are the cheapest flights from Cusco to Santiago?

Can I find deals for flights from Cuzco to Santiago that include hotel bookings?

How can I find direct flights from Cuzco to Santiago?

Can I find deals for business class flights from Cuzco to Santiago?

What is the cheapest month to book a flight from Cusco to Santiago?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Cuzco to Santiago

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Top airline flying from Cuzco to Santiago

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Cheapest flights from Cuzco to Santiago
Explore the most affordable flight options available from Cuzco to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.