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$420+ Cheap flights from Columbus to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — SCL
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheap flight deals from Columbus to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 15, 2025.

Round-trip from

$753
(Avianca Connect)

One-way from

$420
(Air Canada)

Popular in

December

Cheapest in

October

Average price

$907
From Columbus to Santiago Arturo Merino Benitez
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One-way flight from Columbus to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 5% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Columbus to Santiago

Cheapest flights from Columbus to Santiago
Explore the most affordable flight options available from Columbus to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This Avianca Connect deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/45:15 amCMH - SCL
2 stops23h 00mMultiple Airlines
vie. 10/1012:55 amSCL - CMH
2 stops18h 43mMultiple Airlines
Deal found 9/14$753
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/1912:14 pmCMH - SCL
1 stop16h 41mLATAM Airlines
vie. 11/2811:10 pmSCL - CMH
1 stop15h 42mLATAM Airlines
Deal found 9/14$788
This LATAM Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/217:00 amCMH - SCL
2 stops21h 35mLATAM Airlines
dom. 11/3010:25 pmSCL - CMH
2 stops27h 53mLATAM Airlines
Deal found 9/14$804
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/47:07 amCMH - SCL
1 stop21h 38mLATAM Airlines
sáb. 10/1110:50 pmSCL - CMH
1 stop19h 50mLATAM Airlines
Deal found 9/14$817
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/2911:12 amCMH - SCL
1 stop20h 13mAmerican Airlines
lun. 1/1210:15 pmSCL - CMH
1 stop15h 00mAmerican Airlines
Deal found 9/14$868

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Columbus to Santiago that are best for you.

Fly from

Columbus

Fly to

Santiago

Route

Depart

Return

Price

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

sáb. 10/4

5:15 am-5:15 am

2 stops23h 00m

Santiago Arturo Merino Benitez

vie. 10/10

12:55 am-6:38 pm

2 stops18h 43m

$753

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

mié. 11/19

12:14 pm-6:55 am

1 stop16h 41m

Santiago Arturo Merino Benitez

vie. 11/28

11:10 pm-12:52 pm

1 stop15h 42m

$788

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

sáb. 10/4

7:07 am-5:45 am

1 stop21h 38m

Santiago Arturo Merino Benitez

sáb. 10/11

10:50 pm-5:40 pm

1 stop19h 50m

$817

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

lun. 12/29

11:12 am-9:25 am

1 stop20h 13m

Santiago Arturo Merino Benitez

lun. 1/12

10:15 pm-11:15 am

1 stop15h 00m

$868

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

vie. 1/23

9:30 am-7:00 am

2 stops43h 30m

$420

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

jue. 12/25

9:21 am-11:41 pm

3 stops36h 20m

$477

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

jue. 12/25

4:00 pm-3:30 pm

2 stops21h 30m

$530

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

jue. 12/25

8:05 am-7:40 am

1 stop21h 35m

$543

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

jue. 12/25

7:00 am-7:45 am

1 stop22h 45m

$543

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

vie. 1/23

9:55 am-11:05 am

3 stops23h 10m

$583

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Columbus to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Santiago

What is the cheapest month to book a flight from Columbus to Santiago?

Currently, April is the cheapest month in which you can book a flight from Columbus to Santiago (average of $752). Flying from Columbus to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SCL?

Find hourly flight availability from Columbus to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

When flying from Columbus to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 17% versus a flight in the afternoon.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated septiembre 15, 2025.
See what other customers who have flown with Delta and LATAM Airlines from Columbus to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Columbus to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Columbus?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Columbus. Booking flights from Columbus to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Columbus from 2 different airlines.

  • How long is the flight from Columbus to Santiago?

    Airlines like LATAM Airlines fly from Columbus to Santiago in about 16h 41m. The time it takes to get you to your destination can typically vary by up to . The distance from Columbus to Santiago is about 5126 mi.

  • What are the cheapest airlines flying from Columbus to Santiago round-trip?

    According to our current data, Delta ($732), and LATAM Airlines ($732) offers the cheapest pricing from Columbus to Santiago. Delta is currently priced 24% below the average price you’ll pay for this route.

  • Can I find deals for flights from Columbus to Santiago that include hotel bookings?

    Yes. In addition to deals on Columbus to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Santiago.

  • Can I find deals for business class flights from Columbus to Santiago?

    Yes. Cheapflights offers flight deals from Columbus to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Columbus to Santiago (average of $752). Flying from Columbus to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Columbus to Santiago

Discover the top 2 airlines that operate flights from Columbus to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$732Average$1,026FlexibilityNo cancel feeOn-time81%
DeltaCheapest$732Average$1,009FlexibilityNo cancel feeOn-timeN/A

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