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$283+ Cheap flights from Columbus to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — SCL
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Columbus to Santiago

Cheapest flights from Columbus to Santiago
Explore the most affordable flight options available from Columbus to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:00 amCMH - SCL
1 stop21h 10mLATAM Airlines
Fri 1/212:20 amSCL - CMH
2 stops25h 53mLATAM Airlines
Deal found 12/17$2,299
This Air Canada deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/199:30 amCMH - SCL
3 stops34h 29mMultiple Airlines
Sat 1/34:25 pmSCL - CMH
2 stops30h 31mMultiple Airlines
Deal found 12/16$8,222

Find flight deals from Columbus to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Round-trip from

$748
(Mytrip)

One-way from

$283
(Avianca Connect)

Popular in

December

Cheapest in

April

Average price

$1,342
From Columbus to Santiago Arturo Merino Benitez
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One-way flight from Columbus to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 9% potential increase in price ($108 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Columbus to Santiago that are best for you.

Fly from

Columbus

Fly to

Santiago

Route

Depart

Return

Price

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 5/13

7:00 am-6:50 am

1 stop23h 50m

Santiago Arturo Merino Benitez

Wed 5/20

8:40 pm-11:36 am

1 stop14h 56m

$787

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 6/1

12:05 pm-6:50 am

1 stop18h 45m

Santiago Arturo Merino Benitez

Mon 6/22

11:05 pm-6:49 pm

2 stops19h 44m

$787

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 1/19

12:57 pm-6:55 am

1 stop15h 58m

Santiago Arturo Merino Benitez

Sat 3/21

10:30 pm-11:57 am

1 stop14h 27m

$788

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Tue 6/9

10:05 am-7:15 am

1 stop21h 10m

Santiago Arturo Merino Benitez

Wed 7/15

8:40 pm-1:00 pm

1 stop16h 20m

$804

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Thu 5/7

12:50 pm-7:15 am

1 stop18h 25m

Santiago Arturo Merino Benitez

Thu 5/14

8:40 pm-2:30 pm

1 stop17h 50m

$804

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 6/1

2:20 pm-7:15 am

1 stop16h 55m

Santiago Arturo Merino Benitez

Mon 6/22

8:40 pm-1:00 pm

1 stop16h 20m

$804

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 6/8

7:00 am-6:00 am

2 stops23h 00m

Santiago Arturo Merino Benitez

Tue 7/14

11:05 pm-6:49 pm

2 stops19h 44m

$804

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 6/8

10:05 am-7:15 am

1 stop21h 10m

Santiago Arturo Merino Benitez

Mon 7/13

11:05 pm-6:49 pm

2 stops19h 44m

$804

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 4/8

6:00 am-4:15 am

2 stops22h 15m

$283

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 4/8

7:11 am-6:50 am

1 stop23h 39m

$498

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 11 results
1
2

Best time to book a flight from Columbus to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Santiago

What is the cheapest month to book a flight from Columbus to Santiago?

Currently, January is the cheapest month in which you can book a flight from Columbus to Santiago (average of $753). Flying from Columbus to Santiago in March is currently the most expensive (average of $920). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SCL?

Find hourly flight availability from Columbus to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

When flying from Columbus to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 25% versus a flight in the evening.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 18, 2025.
See what other customers who have flown with Delta and LATAM Airlines from Columbus to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,009 reviews

Crew

8.5

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,009 reviews
Delta
7.9
Good
8,009 reviews

Crew

8.5

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,893 reviews
Delta
7.9
Good
8,009 reviews

Crew

8.5

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Columbus?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Columbus. Booking flights from Columbus to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Columbus from 2 different airlines.

  • How long is the flight from Columbus to Santiago?

    Airlines like LATAM Airlines fly from Columbus to Santiago in about 23h 50m. The time it takes to get you to your destination can typically vary by up to . The distance from Columbus to Santiago is about 5126 mi.

  • What are the cheapest airlines flying from Columbus to Santiago round-trip?

    According to our current data, LATAM Airlines ($748), and Delta ($768) offers the cheapest pricing from Columbus to Santiago. LATAM Airlines is currently priced 27% below the average price you’ll pay for this route.

  • Can I find deals for flights from Columbus to Santiago that include hotel bookings?

    Yes. In addition to deals on Columbus to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Santiago.

  • Can I find deals for business class flights from Columbus to Santiago?

    Yes. Cheapflights offers flight deals from Columbus to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Santiago?

    Currently, January is the cheapest month in which you can book a flight from Columbus to Santiago (average of $753). Flying from Columbus to Santiago in March is currently the most expensive (average of $920). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Columbus to Santiago

Discover the top 2 airlines that operate flights from Columbus to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$748Average$1,037FlexibilityNo cancel feeOn-time81%
DeltaCheapest$768Average$929FlexibilityNo cancel feeOn-timeN/A

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