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$420+ Cheap flights from Columbus to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — SCL
Dec 2 — Dec 91
Tue 12/2
Tue 12/9
1 adult, Economy
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Cheap flight deals from Columbus to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 2, 2025.

Round-trip from

$771
(Mytrip)

One-way from

$420
(Air Canada)

Popular in

December

Cheapest in

October

Average price

$896
From Columbus to Santiago Arturo Merino Benitez
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One-way flight from Columbus to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 8% potential increase in price ($94 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Columbus to Santiago

Cheapest flights from Columbus to Santiago
Explore the most affordable flight options available from Columbus to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2025.

This KAYAK deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:08 amCMH - SCL
2 stops19h 22mLATAM Airlines
Sun 11/3011:10 pmSCL - CMH
1 stop20h 24mLATAM Airlines
Deal found 11/2$1,008
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:00 amCMH - SCL
1 stop23h 40mDelta
Sun 11/3011:10 pmSCL - CMH
1 stop20h 24mDelta
Deal found 11/2$1,249
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:28 pmCMH - SCL
3 stops32h 46mMultiple Airlines
Mon 1/53:37 pmSCL - CMH
2 stops27h 56mMultiple Airlines
Deal found 11/2$1,475
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:14 amCMH - SCL
2 stops25h 26mMultiple Airlines
Fri 1/212:35 pmSCL - CMH
2 stops30h 58mMultiple Airlines
Deal found 11/1$1,486
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amCMH - SCL
3 stops44h 55mMultiple Airlines
Sun 1/44:25 pmSCL - CMH
3 stops33h 32mMultiple Airlines
Deal found 11/2$1,591

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from Columbus to Santiago that are best for you.

Fly from

Columbus

Fly to

Santiago

Route

Depart

Return

Price

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 3/11

12:05 pm-5:55 am

1 stop16h 50m

Santiago Arturo Merino Benitez

Tue 3/31

10:55 pm-6:00 pm

1 stop20h 05m

$732

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Thu 1/1

11:14 am-6:40 am

2 stops17h 26m

Santiago Arturo Merino Benitez

Thu 1/8

11:24 am-9:55 am

2 stops24h 31m

$773

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Thu 3/26

8:10 am-7:00 am

1 stop21h 50m

Santiago Arturo Merino Benitez

Sun 4/5

11:25 pm-11:57 pm

2 stops24h 32m

$784

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Sun 1/4

1:11 pm-7:40 am

1 stop16h 29m

Santiago Arturo Merino Benitez

Fri 1/16

6:30 pm-11:59 am

2 stops19h 29m

$844

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Sat 1/24

6:45 am-10:39 am

2 stops25h 54m

Santiago Arturo Merino Benitez

Sat 1/31

8:15 am-9:55 am

3 stops27h 40m

$856

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Tue 3/17

9:30 am-11:15 am

1 stop24h 45m

Santiago Arturo Merino Benitez

Thu 3/19

7:55 pm-8:56 pm

1 stop26h 01m

$883

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 1/23

9:30 am-6:50 am

2 stops43h 20m

$420

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 1/23

7:05 am-6:55 am

1 stop21h 50m

$569

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/31

Best time to book a flight from Columbus to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Santiago

What is the cheapest month to book a flight from Columbus to Santiago?

Currently, March is the cheapest month in which you can book a flight from Columbus to Santiago (average of $732). Flying from Columbus to Santiago in June is currently the most expensive (average of $1,073). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SCL?

Find hourly flight availability from Columbus to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 2, 2025.

When flying from Columbus to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 25% versus a flight in the evening.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated November 2, 2025.
See what other customers who have flown with Delta and LATAM Airlines from Columbus to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,999 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Delta
7.9
Good
7,999 reviews
Delta
7.9
Good
7,999 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
LATAM Airlines
7.5
Good
1,874 reviews
Delta
7.9
Good
7,999 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Columbus?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Columbus. Booking flights from Columbus to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Columbus from 2 different airlines.

  • How long is the flight from Columbus to Santiago?

    Airlines like LATAM Airlines fly from Columbus to Santiago in about 16h 50m. The time it takes to get you to your destination can typically vary by up to . The distance from Columbus to Santiago is about 5126 mi.

  • What are the cheapest airlines flying from Columbus to Santiago round-trip?

    According to our current data, Delta ($732), and LATAM Airlines ($732) offers the cheapest pricing from Columbus to Santiago. Delta is currently priced 26% below the average price you’ll pay for this route.

  • Can I find deals for flights from Columbus to Santiago that include hotel bookings?

    Yes. In addition to deals on Columbus to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Santiago.

  • Can I find deals for business class flights from Columbus to Santiago?

    Yes. Cheapflights offers flight deals from Columbus to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Santiago?

    Currently, March is the cheapest month in which you can book a flight from Columbus to Santiago (average of $732). Flying from Columbus to Santiago in June is currently the most expensive (average of $1,073). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Columbus to Santiago

Discover the top 2 airlines that operate flights from Columbus to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$732Average$1,033FlexibilityNo cancel feeOn-time81%
DeltaCheapest$732Average$929FlexibilityNo cancel feeOn-timeN/A

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