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$450+ Cheap flights from Cleveland (CLE) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — SCL
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Cleveland to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$707
(Kiwi.com)

One-way from

$450
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$958
From Cleveland Hopkins Intl to Santiago Arturo Merino Benitez
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One-way flight from Cleveland Hopkins Intl to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 5% potential increase in price ($53 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Cleveland to Santiago

Cheapest flights from Cleveland to Santiago
Explore the most affordable flight options available from Cleveland to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/98:20 amCLE - SCL
2 stops43h 55mMultiple Airlines
Sat 8/1611:00 amSCL - CLE
1 stop31h 30mMultiple Airlines
Deal found 7/27$707
This Rumbo deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1812:29 pmCLE - SCL
1 stop18h 16mLATAM Airlines
Mon 9/17:15 amSCL - CLE
2 stops17h 25mLATAM Airlines
Deal found 7/28$787
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/186:29 pmCLE - SCL
1 stop12h 31mDelta
Mon 9/18:40 pmSCL - CLE
1 stop16h 03mDelta
Deal found 7/28$794
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/186:20 amCLE - SCL
1 stop24h 35mAmerican Airlines
Mon 9/19:55 pmSCL - CLE
1 stop26h 26mAmerican Airlines
Deal found 7/28$803
This Copa Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/316:05 amCLE - SCL
2 stops17h 03mCopa Airlines
Sat 8/211:29 amSCL - CLE
2 stops22h 24mCopa Airlines
Deal found 7/27$1,224

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Cleveland to Santiago that are best for you.

Fly from

Cleveland

Fly to

Santiago

Route

Depart

Return

Price

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Sat 8/9

8:20 am-4:15 am

2 stops43h 55m

Santiago Arturo Merino Benitez

Sat 8/16

11:00 am-6:30 pm

1 stop31h 30m

$707

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Mon 8/18

12:29 pm-6:45 am

1 stop18h 16m

Santiago Arturo Merino Benitez

Mon 9/1

7:15 am-12:40 am

2 stops17h 25m

$787

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Mon 8/18

6:29 pm-7:00 am

1 stop12h 31m

Santiago Arturo Merino Benitez

Mon 9/1

8:40 pm-12:43 pm

1 stop16h 03m

$794

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Mon 8/18

6:20 am-6:55 am

1 stop24h 35m

Santiago Arturo Merino Benitez

Mon 9/1

9:55 pm-12:21 am

1 stop26h 26m

$803

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Mon 8/18

6:05 am-10:44 pm

2 stops16h 39m

Santiago Arturo Merino Benitez

Thu 8/21

12:24 am-8:14 pm

2 stops19h 50m

$1,460

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Fri 9/12

7:19 pm-6:45 am

3 stops34h 26m

$450

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Fri 9/12

8:12 am-7:00 am

1 stop21h 48m

$583

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Cleveland to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to Santiago

What is the cheapest month to book a flight from Cleveland to Santiago?

Currently, April is the cheapest month in which you can book a flight from Cleveland to Santiago (average of $752). Flying from Cleveland to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLE to SCL?

Find hourly flight availability from Cleveland to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

It’s optimal to fly from Cleveland to Santiago at noon. By choosing this option you can save up to 7% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Cleveland to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 29, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and Copa Airlines from Cleveland to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,822 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,493 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Cleveland to Santiago round-trip?

    Currently priced at $787, LATAM Airlines will fly you from Cleveland to Santiago and back. In addition to LATAM Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and American Airlines - these airlines can fly you to your destination from $794 and $803, respectively. LATAM Airlines is priced at 14% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Cleveland to Santiago that include hotel bookings?

    Yes. In addition to deals on Cleveland to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Santiago.

  • Can I find deals for business class flights from Cleveland to Santiago?

    Yes. Cheapflights offers flight deals from Cleveland to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Cleveland to Santiago (average of $752). Flying from Cleveland to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Cleveland to Santiago

Discover the top 3 airlines that operate flights from Cleveland to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$758Average$937FlexibilityNo cancel feeOn-time81%
DeltaCheapest$763Average$860FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$782Average$1,037FlexibilityNo cancel feeOn-time71%

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