
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $570 (Kiwi.com) |
One-way from | $260 (Kiwi.com) |
Popular in | February |
Cheapest in | May |
Average price | $843 |
Fly from
Fly to
Route
Depart
Return
Price
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Tue 4/21
3:21 pm-5:03 am
1 stop12h 42m
Santiago Arturo Merino Benitez
Tue 4/28
11:25 am-1:13 am
1 stop14h 48m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 3/2
1:15 pm-8:05 am
1 stop15h 50m
Santiago Arturo Merino Benitez
Sun 3/8
9:20 pm-6:28 pm
1 stop23h 08m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Fri 5/1
2:35 pm-4:15 am
1 stop12h 40m
Santiago Arturo Merino Benitez
Sun 5/17
11:55 pm-1:15 pm
1 stop14h 20m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 3/9
3:22 pm-6:00 am
1 stop12h 38m
Santiago Arturo Merino Benitez
Wed 3/18
1:17 am-1:31 pm
1 stop14h 14m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Tue 3/10
8:34 am-11:49 pm
1 stop13h 15m
Santiago Arturo Merino Benitez
Sun 3/15
5:21 am-1:04 am
1 stop21h 43m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 4/6
8:06 am-5:03 am
1 stop19h 57m
Santiago Arturo Merino Benitez
Sat 4/11
12:46 am-1:58 pm
1 stop14h 12m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 3/2
5:53 pm-2:05 pm
2 stops17h 12m
Santiago Arturo Merino Benitez
Sun 3/8
11:25 pm-5:10 pm
2 stops19h 45m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Tue 5/19
1:30 pm-6:50 am
1 stop16h 20m
Santiago Arturo Merino Benitez
Tue 5/26
8:40 pm-12:09 pm
1 stop16h 29m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 2/2
4:50 pm-8:50 am
1 stop13h 00m
Santiago Arturo Merino Benitez
Wed 3/11
9:45 pm-2:44 pm
1 stop18h 59m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Thu 5/7
6:10 pm-2:05 pm
2 stops18h 55m
Santiago Arturo Merino Benitez
Sat 5/16
8:40 pm-10:04 am
1 stop14h 24m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*2 stars |
The price you pay for your flight from Chicago O'Hare Intl Airport to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 38 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Currently, February is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santiago (average of $408). Flying from Chicago O'Hare Intl Airport to Santiago in August is currently the most expensive (average of $890). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
About 0% of weekly flights between Chicago and Santiago have experienced delays in the past year, with the average delay time being 0 minutes.
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
Panama City (PTY) – chosen by Cheapflights users on 80% of 1-stop itineraries from Chicago O'Hare Intl Airport to Santiago on Cheapflights.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $667.
Flights via Bogotá (BOG) have the shortest average one-way travel time for 1-stop routes: 12h 40m.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 24m.
Entertainment
Food
Crew
Boarding
Overall
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Entertainment
Food
Crew
Boarding
Overall
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Entertainment
Food
Crew
Boarding
Overall
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Entertainment
Food
Crew
Boarding
Overall
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Entertainment
Food
Crew
Boarding
Overall
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Entertainment
Food
Crew
Boarding
Overall
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$484 | Average$951 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$558 | Average$728 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$615 | Average$811 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$626 | Average$856 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$626 | Average$887 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$630 | Average$1,003 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$637 | Average$901 | FlexibilityNo cancel fee | On-time81% |