$291+ Cheap flights from O'Hare Intl (ORD) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — SCL
Sep 8 — Sep 151
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from O'Hare Intl to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from O'Hare Intl to Santiago
Cheapest
Best
Last-minute
One-way
Cheapest flights from O'Hare Intl to SantiagoExplore the most affordable flight options available from O'Hare Intl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
Explore the most affordable flight options available from O'Hare Intl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:27 am -
2 stops23h 13m
Sun 11/812:15 pm -
1 stop14h 56m
Deal found 8/8![Multiple Airlines logo]()
$608
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:59 pm -
2 stops30h 51m
Sat 10/247:40 am -
1 stop15h 40m
Deal found 8/5![Multiple Airlines logo]()
$653
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:59 pm -
2 stops30h 51m
Wed 10/287:25 am -
1 stop15h 55m
Deal found 8/5![Multiple Airlines logo]()
$655
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:26 am -
2 stops17h 20m
Tue 11/2412:15 pm -
1 stop14h 56m
Deal found 8/8![Multiple Airlines logo]()
$670
This Mytrip deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:45 am -
1 stop15h 10m
Sat 10/314:25 pm -
1 stop30h 55m
Deal found 8/9![Multiple Airlines logo]()
$676
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/223:50 pm -
2 stops54h 32m
Tue 9/2912:22 pm -
1 stop14h 40m
Deal found 8/8![Multiple Airlines logo]()
$678
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:44 pm -
2 stops49h 55m
Sun 9/205:14 am -
1 stop21h 48m
Deal found 8/5![Multiple Airlines logo]()
$690
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:44 pm -
2 stops32h 30m
Sat 10/247:40 am -
1 stop15h 40m
Deal found 8/5![Multiple Airlines logo]()
$693
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:44 pm -
2 stops32h 30m
Thu 10/297:25 am -
1 stop15h 55m
Deal found 8/5![Multiple Airlines logo]()
$695
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:59 pm -
2 stops30h 51m
Wed 9/24:14 am -
1 stop21h 48m
Deal found 8/9![Multiple Airlines logo]()
$696
Best flights from O'Hare Intl to SantiagoDiscover carefully curated flight deals from O'Hare Intl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
Discover carefully curated flight deals from O'Hare Intl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:35 am -
1 stop17h 03m
Mon 11/1612:15 pm -
1 stop14h 56m
Deal found 8/8![Copa Airlines logo]()
$744
This Arajet deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 am -
1 stop21h 53m
Thu 11/1910:00 am -
1 stop15h 40m
Deal found 8/8![Arajet logo]()
$747
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:29 pm -
1 stop12h 31m
Thu 9/249:30 pm -
2 stops17h 24m
Deal found 8/9![American Airlines logo]()
$761
This FlightHub deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:50 pm -
2 stops16h 05m
Wed 9/25:40 am -
2 stops19h 17m
Deal found 8/6![LATAM Airlines logo]()
$764
This Copa Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:13 pm -
1 stop31h 06m
Wed 11/181:22 am -
1 stop14h 24m
Deal found 8/8![Copa Airlines logo]()
$744
This FlightHub deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:30 am -
2 stops17h 25m
Sat 11/148:13 am -
2 stops18h 46m
Deal found 8/6![LATAM Airlines logo]()
$796
This Copa Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:01 am -
1 stop13h 38m
Sat 9/195:14 am -
1 stop21h 48m
Deal found 8/9![Copa Airlines logo]()
$780
This FlightHub deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:00 pm -
1 stop16h 25m
Wed 9/210:55 pm -
1 stop19h 06m
Deal found 8/7![LATAM Airlines logo]()
$813
This Copa Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:02 am -
1 stop14h 24m
Fri 10/3012:23 pm -
1 stop14h 42m
Deal found 8/6![Copa Airlines logo]()
$791
This Copa Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:01 am -
1 stop14h 21m
Tue 9/85:14 am -
1 stop21h 48m
Deal found 8/8![Copa Airlines logo]()
$803
Last-minute flights from O'Hare Intl to SantiagoDiscover last-minute flight deals from O'Hare Intl to Santiago. Data last updated August 9, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to Santiago. Data last updated August 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:59 pm -
2 stops30h 51m
Wed 9/24:14 am -
1 stop21h 48m
Deal found 8/9![Multiple Airlines logo]()
$696
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:05 am -
2 stops19h 55m
Wed 9/24:14 am -
1 stop21h 48m
Deal found 8/9![Multiple Airlines logo]()
$719
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:30 am -
2 stops31h 05m
Wed 9/28:20 pm -
2 stops28h 27m
Deal found 8/7![Multiple Airlines logo]()
$707
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:59 pm -
2 stops30h 51m
Sat 10/247:40 am -
1 stop15h 40m
Deal found 8/5![Multiple Airlines logo]()
$653
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:59 pm -
2 stops30h 51m
Wed 10/287:25 am -
1 stop15h 55m
Deal found 8/5![Multiple Airlines logo]()
$655
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:44 pm -
2 stops32h 30m
Sat 10/247:40 am -
1 stop15h 40m
Deal found 8/5![Multiple Airlines logo]()
$693
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:44 pm -
2 stops32h 30m
Wed 10/287:25 am -
1 stop15h 55m
Deal found 8/5![Multiple Airlines logo]()
$695
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:44 pm -
2 stops30h 16m
Sat 10/247:40 am -
1 stop15h 40m
Deal found 8/5![Multiple Airlines logo]()
$720
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:44 pm -
2 stops49h 55m
Sun 9/205:14 am -
1 stop21h 48m
Deal found 8/5![Multiple Airlines logo]()
$690
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/223:50 pm -
2 stops54h 32m
Tue 9/2912:22 pm -
1 stop14h 40m
Deal found 8/8![Multiple Airlines logo]()
$678
One-way flights from O'Hare Intl to SantiagoSearch for one-way flight options from O'Hare Intl to Santiago. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
Search for one-way flight options from O'Hare Intl to Santiago. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:01 pm -
3 stops39h 34m
Deal found 8/6![Multiple Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:05 am -
2 stops19h 55m
Deal found 8/7![Multiple Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:44 pm -
2 stops49h 55m
Deal found 8/6![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:44 pm -
2 stops33h 16m
Deal found 8/7![Multiple Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:50 pm -
2 stops32h 56m
Deal found 8/5![Multiple Airlines logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:44 pm -
2 stops32h 26m
Deal found 8/5![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:59 pm -
2 stops30h 51m
Deal found 8/7![Multiple Airlines logo]()
$325
Find flight deals from O'Hare Intl to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $608 (Kiwi.com) |
One-way from | $291 (Kiwi.com) |
Popular in | July |
Cheapest in | June |
Average price | $955 |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Fri 11/6
7:35 am-3:38 am
1 stop17h 03m
Santiago Arturo Merino Benitez
Mon 11/16
12:15 pm-12:11 am
1 stop14h 56m
$744
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Sat 11/7
2:13 pm-12:19 am
1 stop31h 06m
Santiago Arturo Merino Benitez
Wed 11/18
1:22 am-12:46 pm
1 stop14h 24m
$744
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Fri 11/6
5:45 am-6:38 am
1 stop21h 53m
Santiago Arturo Merino Benitez
Thu 11/19
10:00 am-10:40 pm
1 stop15h 40m
$747
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Sat 9/12
5:29 pm-8:00 am
1 stop12h 31m
Santiago Arturo Merino Benitez
Thu 9/24
9:30 pm-12:54 pm
2 stops17h 24m
$761
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Thu 8/27
1:50 pm-6:55 am
2 stops16h 05m
Santiago Arturo Merino Benitez
Wed 9/2
5:40 am-11:57 pm
2 stops19h 17m
$764
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Wed 9/16
8:01 am-11:39 pm
1 stop13h 38m
Santiago Arturo Merino Benitez
Sat 9/19
5:14 am-1:02 am
1 stop21h 48m
$780
Quickest round-trip
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Fri 8/28
8:02 am-11:26 pm
1 stop14h 24m
Santiago Arturo Merino Benitez
Fri 10/30
12:23 pm-1:05 am
1 stop14h 42m
$791
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Thu 11/5
10:30 am-6:55 am
2 stops17h 25m
Santiago Arturo Merino Benitez
Sat 11/14
8:13 am-11:59 pm
2 stops18h 46m
$796
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Tue 9/1
8:01 am-11:22 pm
1 stop14h 21m
Santiago Arturo Merino Benitez
Tue 9/8
5:14 am-1:02 am
1 stop21h 48m
$803
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Mon 8/24
1:00 pm-6:25 am
1 stop16h 25m
Santiago Arturo Merino Benitez
Wed 9/2
10:55 pm-5:01 pm
1 stop19h 06m
$813
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from O'Hare Intl to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Santiago in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from O'Hare Intl to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from O'Hare Intl with our price prediction graph.
ORD-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to Santiago
Prices
Delays
More
How far ahead should I book a flight from Chicago O'Hare Intl Airport to Santiago?
The price you pay for your flight from Chicago O'Hare Intl Airport to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 37 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Santiago?
Currently, June is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santiago (average of $638). Flying from Chicago O'Hare Intl Airport to Santiago in July is currently the most expensive (average of $1,093). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to Santiago?
Airfare is below average for this route at the moment.
Chicago O'Hare Intl Airport to Santiago flights typically cost between $864 and $1,067 in October.The cheapest round-trip price found within the last 5 days was $608 on Multiple Airlines (Oct 31-Nov 8).
How often are flights from Chicago to Santiago delayed?
About 0% of weekly flights between Chicago and Santiago have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for Chicago to Santiago flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What’s the top layover airport for flights from Chicago O'Hare Intl Airport to Santiago?
Share of 1-stop round-trip flights from Chicago O'Hare Intl Airport to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 80% of 1-stop itineraries from Chicago O'Hare Intl Airport to Santiago on Cheapflights.
What’s the cheapest layover airport for flights from Chicago O'Hare Intl Airport to Santiago?
Average round-trip fare for 1-stop flights from Chicago O'Hare Intl Airport to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $667.
What’s the fastest layover option from Chicago O'Hare Intl Airport to Santiago?
Shortest average travel time for 1-stop one-way flights from Chicago O'Hare Intl Airport to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 12h 58m.
Which airport typically offers the quickest layover for flights from Chicago O'Hare Intl Airport to Santiago?
Average layover duration for 1-stop one-way flights from Chicago O'Hare Intl Airport to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 24m.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated August 9, 2026.
See what other customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Chicago O'Hare Intl Airport to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from O'Hare Intl
Popular flights
Santiago flight routes
Alternative routes for O'Hare Intl to Santiago
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from O'Hare Intl to Santiago by cabin class
Find flights from O'Hare Intl to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
O'Hare Intl and Santiago flights
Browse other O'Hare Intl and Santiago flight options. Last updated on August 9, 2026.
Other flights from O'Hare Intl
Browse through other flights departing from O'Hare Intl. Flights are based on user searches made on Cheapflights and were last updated on August 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 9, 2026.
Top 6 airlines flying from O'Hare Intl to Santiago
Discover the top 6 airlines that operate flights from O'Hare Intl to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$537 | Average$700 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$540 | Average$777 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$546 | Average$895 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$595 | Average$879 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$597 | Average$890 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$626 | Average$788 | FlexibilityNo cancel fee | On-time69% |