
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $550 (Copa Airlines) |
One-way from | $298 (Mytrip) |
Popular in | August |
Cheapest in | June |
Average price | $673 |
Fly from
Fly to
Route
Depart
Return
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sat 4/25
8:06 am-11:26 pm
1 stop14h 20m
Santiago Arturo Merino Benitez
Sat 5/2
11:17 am-1:15 am
1 stop14h 58m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sun 5/17
8:02 am-10:43 pm
1 stop13h 41m
Santiago Arturo Merino Benitez
Sun 5/24
11:17 am-1:15 am
1 stop14h 58m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sun 4/19
8:06 am-11:26 pm
1 stop14h 20m
Santiago Arturo Merino Benitez
Sat 4/25
11:25 am-1:13 am
1 stop14h 48m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sat 4/25
8:06 am-11:26 pm
1 stop14h 20m
Santiago Arturo Merino Benitez
Mon 5/4
11:17 am-1:15 am
1 stop14h 58m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Fri 6/5
8:02 am-1:50 am
1 stop16h 48m
Santiago Arturo Merino Benitez
Fri 6/12
11:17 am-4:00 am
1 stop17h 43m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Fri 5/15
8:02 am-10:43 pm
1 stop13h 41m
Santiago Arturo Merino Benitez
Sun 5/24
11:17 am-1:15 am
1 stop14h 58m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Thu 5/28
8:02 am-10:43 pm
1 stop13h 41m
Santiago Arturo Merino Benitez
Mon 6/1
11:17 am-4:00 am
1 stop17h 43m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Thu 4/30
3:05 pm-5:10 am
1 stop13h 05m
Santiago Arturo Merino Benitez
Tue 5/5
2:22 am-1:15 am
1 stop23h 53m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Thu 5/28
3:21 pm-5:10 am
1 stop12h 49m
Santiago Arturo Merino Benitez
Mon 6/1
12:38 am-2:06 pm
1 stop14h 28m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 6/15
8:02 am-10:43 pm
1 stop13h 41m
Santiago Arturo Merino Benitez
Mon 7/6
11:22 am-4:00 am
1 stop17h 38m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*2 stars |
The price you pay for your flight from Chicago O'Hare Intl Airport to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Currently, May is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santiago (average of $326). Flying from Chicago O'Hare Intl Airport to Santiago in August is currently the most expensive (average of $767). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
About 0% of weekly flights between Chicago and Santiago have experienced delays in the past year, with the average delay time being 0 minutes.
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
Panama City (PTY) – chosen by Cheapflights users on 80% of 1-stop itineraries from Chicago O'Hare Intl Airport to Santiago on Cheapflights.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $667.
Flights via Bogotá (BOG) have the shortest average one-way travel time for 1-stop routes: 12h 40m.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 24m.
Entertainment
Crew
Food
Comfort
Overall
Boarding
Reviews
Katerine,Mar 2026
LAX - PTY
Entertainment
Crew
Food
Comfort
Overall
Boarding
Reviews
Katerine,Mar 2026
LAX - PTY
Entertainment
Crew
Food
Comfort
Overall
Boarding
Reviews
Katerine,Mar 2026
LAX - PTY
Entertainment
Crew
Food
Comfort
Overall
Boarding
Reviews
Katerine,Mar 2026
LAX - PTY
Entertainment
Crew
Food
Comfort
Overall
Boarding
Reviews
Katerine,Mar 2026
LAX - PTY
Entertainment
Crew
Food
Comfort
Overall
Boarding
Reviews
Katerine,Mar 2026
LAX - PTY
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$513 | Average$709 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$539 | Average$744 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$540 | Average$740 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$568 | Average$844 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$597 | Average$895 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$626 | Average$788 | FlexibilityNo cancel fee | On-time69% |