$274+ Cheap flights from O'Hare Intl (ORD) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — SCL
Jul 2 — Jul 91
Round-trip
1 adult, Economy
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Cheapest flights from O'Hare Intl to SantiagoExplore the most affordable flight options available from O'Hare Intl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 2, 2026.
Explore the most affordable flight options available from O'Hare Intl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:30 pm
ORD
- SCL
2 stops32h 26m
Multiple Airlines
Tue 9/1510:55 pm
SCL
- ORD
1 stop20h 18m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$619
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:49 pm
ORD
- SCL
2 stops49h 43m
Multiple Airlines
Mon 10/512:23 pm
SCL
- ORD
1 stop14h 34m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$625
This Kiwi.com deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:30 pm
ORD
- SCL
2 stops28h 09m
Multiple Airlines
Tue 9/1510:55 pm
SCL
- ORD
1 stop20h 18m
Multiple Airlines
Deal found 5/28![Multiple Airlines logo]()
$628
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:13 pm
ORD
- SCL
2 stops32h 07m
Multiple Airlines
Thu 8/2010:55 pm
SCL
- ORD
1 stop19h 11m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$631
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:26 am
ORD
- SCL
2 stops16h 30m
Multiple Airlines
Mon 10/512:23 pm
SCL
- ORD
1 stop14h 34m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$632
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:05 am
ORD
- SCL
2 stops22h 05m
Multiple Airlines
Sun 10/2512:23 pm
SCL
- ORD
1 stop14h 42m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$644
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:26 am
ORD
- SCL
2 stops16h 30m
Multiple Airlines
Sun 10/48:40 pm
SCL
- ORD
1 stop15h 29m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$645
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:13 pm
ORD
- SCL
2 stops32h 07m
Multiple Airlines
Fri 8/2111:22 am
SCL
- ORD
1 stop14h 40m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$647
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:05 am
ORD
- SCL
2 stops19h 11m
Multiple Airlines
Fri 10/2312:23 pm
SCL
- ORD
1 stop14h 34m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$649
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:13 pm
ORD
- SCL
2 stops35h 01m
Multiple Airlines
Tue 8/2511:22 am
SCL
- ORD
1 stop14h 40m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$652
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:13 pm
ORD
- SCL
2 stops32h 07m
Multiple Airlines
Tue 8/1812:43 am
SCL
- ORD
1 stop14h 16m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$653
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:49 pm
ORD
- SCL
2 stops25h 43m
Multiple Airlines
Sat 10/1012:23 pm
SCL
- ORD
1 stop14h 34m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$657
Best flights from O'Hare Intl to SantiagoDiscover carefully curated flight deals from O'Hare Intl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 2, 2026.
Discover carefully curated flight deals from O'Hare Intl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 2, 2026.
This LATAM Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:40 am
ORD
- SCL
2 stops17h 10m
LATAM Airlines
Tue 11/1011:05 pm
SCL
- ORD
2 stops21h 29m
LATAM Airlines
Deal found 5/28![LATAM Airlines logo]()
$700
This Copa Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/281:20 am
ORD
- SCL
1 stop23h 30m
Copa Airlines
Sat 8/811:22 am
SCL
- ORD
1 stop14h 40m
Copa Airlines
Deal found 6/1![Copa Airlines logo]()
$723
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2910:35 am
ORD
- SCL
1 stop18h 50m
Delta
Wed 7/1511:25 pm
SCL
- ORD
1 stop19h 10m
Delta
Deal found 6/1![Delta logo]()
$729
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:25 am
ORD
- SCL
1 stop20h 25m
United Airlines
Sun 11/110:45 pm
SCL
- ORD
1 stop13h 40m
United Airlines
Deal found 6/1![United Airlines logo]()
$735
This LATAM Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/141:50 pm
ORD
- SCL
2 stops16h 05m
LATAM Airlines
Sat 8/2911:05 pm
SCL
- ORD
2 stops20h 44m
LATAM Airlines
Deal found 5/28![LATAM Airlines logo]()
$717
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:35 am
ORD
- SCL
1 stop21h 00m
Delta
Tue 6/2311:05 pm
SCL
- ORD
1 stop19h 06m
Delta
Deal found 6/1![Delta logo]()
$735
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/221:46 pm
ORD
- SCL
1 stop16h 29m
Delta
Sat 6/278:40 pm
SCL
- ORD
1 stop18h 49m
Delta
Deal found 6/2![Delta logo]()
$735
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:00 am
ORD
- SCL
1 stop23h 15m
Delta
Tue 8/410:55 pm
SCL
- ORD
1 stop23h 57m
Delta
Deal found 6/1![Delta logo]()
$735
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2711:23 am
ORD
- SCL
1 stop18h 52m
Delta
Sat 7/47:55 pm
SCL
- ORD
2 stops19h 34m
Delta
Deal found 5/28![Delta logo]()
$735
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:00 pm
ORD
- SCL
1 stop16h 25m
Delta
Sun 7/128:40 pm
SCL
- ORD
2 stops22h 49m
Delta
Deal found 5/30![Delta logo]()
$740
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:03 am
ORD
- SCL
1 stop22h 12m
Delta
Fri 7/248:40 pm
SCL
- ORD
2 stops18h 06m
Delta
Deal found 6/2![Delta logo]()
$740
Last-minute flights from O'Hare Intl to SantiagoDiscover last-minute flight deals from O'Hare Intl to Santiago. Data last updated June 2, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to Santiago. Data last updated June 2, 2026 and is based on user searches.
This LATAM Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/151:00 pm
ORD
- SCL
1 stop16h 25m
LATAM Airlines
Mon 7/610:55 pm
SCL
- ORD
1 stop19h 11m
LATAM Airlines
Deal found 5/29![LATAM Airlines logo]()
$704
This LATAM Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/169:48 am
ORD
- SCL
2 stops18h 47m
LATAM Airlines
Tue 7/710:55 pm
SCL
- ORD
1 stop19h 11m
LATAM Airlines
Deal found 5/29![LATAM Airlines logo]()
$678
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/169:55 am
ORD
- SCL
1 stop20h 10m
American Airlines
Tue 7/79:00 pm
SCL
- ORD
1 stop23h 53m
American Airlines
Deal found 6/2![American Airlines logo]()
$720
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1410:05 am
ORD
- SCL
1 stop19h 55m
American Airlines
Tue 7/289:00 pm
SCL
- ORD
1 stop18h 58m
American Airlines
Deal found 6/2![American Airlines logo]()
$705
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:05 pm
ORD
- SCL
1 stop13h 55m
American Airlines
Tue 7/219:00 pm
SCL
- ORD
1 stop14h 59m
American Airlines
Deal found 5/30![American Airlines logo]()
$707
This Despegar deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/143:22 pm
ORD
- SCL
1 stop14h 53m
LATAM Airlines
Tue 7/2111:00 pm
SCL
- ORD
2 stops20h 45m
LATAM Airlines
Deal found 5/30![LATAM Airlines logo]()
$712
This Copa Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/281:20 am
ORD
- SCL
1 stop23h 30m
Copa Airlines
Sat 8/811:22 am
SCL
- ORD
1 stop14h 40m
Copa Airlines
Deal found 5/31![Copa Airlines logo]()
$661
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:13 pm
ORD
- SCL
2 stops31h 37m
Multiple Airlines
Mon 8/102:56 am
SCL
- ORD
1 stop23h 06m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$680
One-way flights from O'Hare Intl to SantiagoSearch for one-way flight options from O'Hare Intl to Santiago. Find affordable one-way fares based on user searches. Data last updated June 2, 2026.
Search for one-way flight options from O'Hare Intl to Santiago. Find affordable one-way fares based on user searches. Data last updated June 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:30 pm
ORD
- SCL
2 stops34h 44m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:30 pm
ORD
- SCL
2 stops32h 26m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$295
This deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:45 am
ORD
- SCL
1 stop15h 05m
Arajet
Deal found 6/1![Arajet logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:13 pm
ORD
- SCL
3 stops36h 42m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:29 pm
ORD
- SCL
3 stops36h 31m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:30 pm
ORD
- SCL
2 stops34h 44m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:26 am
ORD
- SCL
2 stops35h 10m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:13 pm
ORD
- SCL
2 stops52h 30m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:55 am
ORD
- SCL
3 stops35h 28m
Multiple Airlines
Deal found 5/28![Multiple Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/179:48 pm
ORD
- SCL
3 stops28h 12m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$369
Find flight deals from O'Hare Intl to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $631 (Kiwi.com) |
One-way from | $274 (Kiwi.com) |
Popular in | August |
Cheapest in | June |
Average price | $688 |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 2, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Tue 11/3
10:40 am-6:50 am
2 stops17h 10m
Santiago Arturo Merino Benitez
Tue 11/10
11:05 pm-5:34 pm
2 stops21h 29m
$700
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Fri 8/14
1:50 pm-6:55 am
2 stops16h 05m
Santiago Arturo Merino Benitez
Sat 8/29
11:05 pm-6:49 pm
2 stops20h 44m
$717
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Tue 7/28
1:20 am-1:50 am
1 stop23h 30m
Santiago Arturo Merino Benitez
Sat 8/8
11:22 am-1:02 am
1 stop14h 40m
$723
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 6/29
10:35 am-6:25 am
1 stop18h 50m
Santiago Arturo Merino Benitez
Wed 7/15
11:25 pm-5:35 pm
1 stop19h 10m
$729
Quickest round-trip
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Wed 10/28
9:25 am-7:50 am
1 stop20h 25m
Santiago Arturo Merino Benitez
Sun 11/1
10:45 pm-9:25 am
1 stop13h 40m
$735
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sat 6/20
7:35 am-5:35 am
1 stop21h 00m
Santiago Arturo Merino Benitez
Tue 6/23
11:05 pm-5:11 pm
1 stop19h 06m
$735
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 6/22
1:46 pm-7:15 am
1 stop16h 29m
Santiago Arturo Merino Benitez
Sat 6/27
8:40 pm-2:29 pm
1 stop18h 49m
$735
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sat 7/25
7:00 am-7:15 am
1 stop23h 15m
Santiago Arturo Merino Benitez
Tue 8/4
10:55 pm-9:52 pm
1 stop23h 57m
$735
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sat 6/27
11:23 am-7:15 am
1 stop18h 52m
Santiago Arturo Merino Benitez
Sat 7/4
7:55 pm-2:29 pm
2 stops19h 34m
$735
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Wed 7/8
1:00 pm-6:25 am
1 stop16h 25m
Santiago Arturo Merino Benitez
Sun 7/12
8:40 pm-6:29 pm
2 stops22h 49m
$740
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from O'Hare Intl to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Santiago in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from O'Hare Intl to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from O'Hare Intl with our price prediction graph.
ORD-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to Santiago
Prices
Delays
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How far ahead should I book a flight from Chicago O'Hare Intl Airport to Santiago?
The price you pay for your flight from Chicago O'Hare Intl Airport to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 37 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Santiago?
Currently, June is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santiago (average of $688). Flying from Chicago O'Hare Intl Airport to Santiago in August is currently the most expensive (average of $1,003). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to Santiago?
How often are flights from Chicago to Santiago delayed?
About 0% of weekly flights between Chicago and Santiago have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for Chicago to Santiago flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What’s the top layover airport for flights from Chicago O'Hare Intl Airport to Santiago?
Share of 1-stop round-trip flights from Chicago O'Hare Intl Airport to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 80% of 1-stop itineraries from Chicago O'Hare Intl Airport to Santiago on Cheapflights.
What’s the cheapest layover airport for flights from Chicago O'Hare Intl Airport to Santiago?
Average round-trip fare for 1-stop flights from Chicago O'Hare Intl Airport to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $667.
What’s the fastest layover option from Chicago O'Hare Intl Airport to Santiago?
Shortest average travel time for 1-stop one-way flights from Chicago O'Hare Intl Airport to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Bogotá (BOG) have the shortest average one-way travel time for 1-stop routes: 12h 40m.
Which airport typically offers the quickest layover for flights from Chicago O'Hare Intl Airport to Santiago?
Average layover duration for 1-stop one-way flights from Chicago O'Hare Intl Airport to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 24m.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 2, 2026.
See what other customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Chicago O'Hare Intl Airport to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Boarding
8.1
Overall
7.9
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Overall
7.9
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Overall
7.9
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Overall
7.9
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Overall
7.9
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Overall
7.9
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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O'Hare Intl and Santiago flights
Browse other O'Hare Intl and Santiago flight options. Last updated on June 2, 2026.
Other flights from O'Hare Intl
Browse through other flights departing from O'Hare Intl. Flights are based on user searches made on Cheapflights and were last updated on June 2, 2026.
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Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 2, 2026.
Top 6 airlines flying from O'Hare Intl to Santiago
Discover the top 6 airlines that operate flights from O'Hare Intl to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$537 | Average$680 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$540 | Average$744 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$567 | Average$790 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$568 | Average$844 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$597 | Average$906 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$626 | Average$796 | FlexibilityNo cancel fee | On-time69% |