
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $655 (Delta) |
One-way from | $289 (Kiwi.com) |
Popular in | August |
Cheapest in | May |
Average price | $1,041 |
Fly from
Fly to
Route
Depart
Return
Price
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 1/12
3:55 pm-9:00 am
1 stop14h 05m
Santiago Arturo Merino Benitez
Mon 1/26
10:35 pm-11:35 am
2 stops16h 00m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sat 1/17
3:53 pm-8:50 am
1 stop13h 57m
Santiago Arturo Merino Benitez
Sat 1/24
10:45 pm-10:07 am
1 stop14h 22m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Thu 1/22
4:50 pm-8:50 am
1 stop13h 00m
Santiago Arturo Merino Benitez
Sat 2/14
10:45 pm-9:17 am
1 stop13h 32m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 2/2
10:35 am-7:40 am
2 stops18h 05m
Santiago Arturo Merino Benitez
Tue 2/17
11:10 pm-4:41 pm
2 stops20h 31m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sun 12/7
10:20 pm-3:20 pm
1 stop14h 00m
Santiago Arturo Merino Benitez
Mon 12/8
1:35 am-8:20 pm
1 stop21h 45m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sun 12/7
7:20 am-5:30 am
2 stops19h 10m
Santiago Arturo Merino Benitez
Mon 12/8
1:35 am-8:20 pm
1 stop21h 45m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Tue 1/27
11:15 am-7:40 am
1 stop17h 25m
Santiago Arturo Merino Benitez
Sat 1/31
8:15 am-11:56 pm
2 stops18h 41m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Fri 1/16
7:05 am-6:10 am
1 stop20h 05m
Santiago Arturo Merino Benitez
Thu 1/22
6:30 pm-10:07 am
2 stops18h 37m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Fri 1/16
11:05 am-6:10 am
2 stops16h 05m
Santiago Arturo Merino Benitez
Fri 1/23
11:25 pm-2:24 pm
2 stops17h 59m
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Thu 1/8
6:57 pm-10:15 pm
2 stops24h 18m
Santiago Arturo Merino Benitez
Mon 1/12
12:35 pm-11:22 am
2 stops25h 47m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy3 stars | Trust Score*2 stars |
The price you pay for your flight from Chicago O'Hare Intl Airport to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 12 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Currently, February is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santiago (average of $452). Flying from Chicago O'Hare Intl Airport to Santiago in August is currently the most expensive (average of $889). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s optimal to fly from Chicago O'Hare Intl Airport to Santiago in the evening. By choosing this option you can save up to 11% on the cost of your flight, compared to a flight in the afternoon.
Panama City (PTY) – chosen by Cheapflights users on 80% of 1-stop itineraries from Chicago O'Hare Intl Airport to Santiago on Cheapflights.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $667.
Flights via Bogotá (BOG) have the shortest average one-way travel time for 1-stop routes: 12h 40m.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 24m.
Food
Overall
Crew
Entertainment
Boarding
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Food
Overall
Crew
Entertainment
Boarding
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Food
Overall
Crew
Entertainment
Boarding
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Food
Overall
Crew
Entertainment
Boarding
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Food
Overall
Crew
Entertainment
Boarding
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Food
Overall
Crew
Entertainment
Boarding
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$484 | Average$951 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$564 | Average$738 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$626 | Average$869 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$626 | Average$890 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$639 | Average$1,028 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$641 | Average$851 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$684 | Average$911 | FlexibilityNo cancel fee | On-time81% |